Alignment of the gene Family HOG000111412 of HOGENOM

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Isoforms are ON
AILMEGL192861_1_1_PE2 NOISO ------------------MDTIFP-PGGDSGLTNSQSEFQKMLIDERVRCAHHKTNYQTL ANOCA45_5_PE11 NOISO ---------------MDTLPNVLSPVGGNADVASSHAEVQKLLIDERIRCEHHKTNYQTL CALJA9_90_PE1 NOISO -----------------------------------------MLIDERLRCEHHKANYQTL CANFA15_38_PE5 NOISO ---------------MDTFPPIFP-PGGDSELTGSQSELQKMLIDERLRCEHHKSNYQTL CAVPO9_7_PE5 NOISO VS--------SSLTNMDTFTNIFP-PGGDSGINS-ESELQRMLADERLRCEHHKTNYQTL CHICK1_PE561 NOISO ---------------MDSLGSLLPPVVGNGDA-ANSQELQKLLIDEKMRCEHHKANYQTI DANRE4_20_PE23 NOISO ---------------------ATVLLGGSTGLTSSDMEFQKMLIDERMRCENHKTNYQTL DASNOGS_3227_PE2 NOISO VV--------SSLTNMDAFPNLFP-PGGDSGLTSSPSEFQKMLIDERLRCEHHKTNYQTL DIPORGS_3028_PE2 NOISO ----------------------FP-SGGDSR--QNEEELQKVLIDERVRCENHKTNYQ-L ECHTEGS_9098_PE3 NOISO ------------------------------------------------------------ FUGRU168_PE55 NOISO -----------------------------------------MLIDERIKSENFRTQYQSL FUGRU3595_PE2 NOISO ------------------------------------------------------------ GASACGROUPIV_23_PE9 NOISO ------------------------MLGLSAGLGGAELELQKMLIDERMKCENHRTNYQTL GORGO12_98_PE3 ENSGGOG00000026256 ---------------MDTFPNNFP-PGGDSGLTGSQSEFQKMLIDERLRCEHHKANYQTL GORGO12_98_PE4 ISOFORMIN VV--------STFTDMDTFPNNFP-PGGDSGLTGSQSEFQKMLIDERLRCEHHKANYQTL HORSE28_21_PE2 ENSECAG00000008428 VV--------SSLTSMDTFPTTFP-PGGDSGLTSSQSDFQKLLIDERLRCEHHKTNYQTL HS12_PE1898 ENSG00000173588 VV--------STFTDMDTFPNNFP-PGGDSGLTGSQSEFQKMLIDERLRCEHHKANYQTL HS12_PE1899 ISOFORMIN VV--------STFTDMDTFPNNFP-PGGDSGLTGSQSEFQKMLIDERLRCEHHKANYQTL HS12_PE1900 ISOFORMIN -----------------------------------------MLIDERLRCEHHKANYQTL LAMPAGS_1526_PE2 NOISO VV--------SSFTNMDTFPTIFP-PGGDSGLTSSQSEFQKMLIDERLRCEHHKTNYQTL LOXAF2_91_PE3 NOISO ---------------MDTFPNIFP-PAGDSGLTSSQSEFQKMLIDERLRCEHHKTNYQTL MACEUGS_4559_PE2 NOISO ------------------------------------------------------------ MACMU11_99_PE2 NOISO ------------------------------------------------------------ MICMUGS_1998_PE2 NOISO ------------------------------------------------------------ MONDO8_74_PE3 NOISO ---------------MDAFANIFP-PGGDTGLTSSQSEFQKMLIDERFRCEHHKTNYQTL MOUSE10_PE1708 NOISO ---------------MDTFPSLFP-PGGDSRLNP-EPEFQNMLIDERVRCEHHKHNYQAL MYOLUGS_2580_PE2 NOISO ------------------------------------------------------------ OCHPRGS_3935_PE2 NOISO ------------------------------------------------------------ ORNANULTRA443_9_PE18 NOISO ---------------MDTSSNIFP-LGGDSGPTCSQLEFQKMLIDERMRCEHHKANYQTL ORYLA23_2_PE19 NOISO TSPTPGWSVPPVQGLEPGVGKHAAVLGLSVGLEGAEKELHKMLIDERMKSETHKTNYQTL OTOGAGS_2326_PE2 NOISO ------------------------------------------------------------ PANTR12_99_PE3 ENSPTRG00000005302 VV--------STFTDMDTFPNNFP-PGGDSGLTASQSEFQKMLIDERLRCEHHKANYQTL POEGU1A_46_PE9 NOISO ---------------MDDLGNLLPLVGESGEA-ANSQEILKLLMDEKMRSEHHKANYQTL PONPY12_100_PE2 NOISO VA--------STFTDMDTFPNNFP-PAGDSGLTGSQSEFQKMLIDERLRCEHHKANYQTL PROCAGS_3333_PE2 NOISO VV--------SSLTNMDAFPNIFP-PAGDSRLTSSQSEFQNMLIDERLRCEHHKTNYQTL PTEVAGS_1643_PE2 NOISO VV--------SSPTNMDTFPTNFP-PSGDSGLTSSQAEFQKMLIDERLRCDHHKTNYQTL RABIT4_75_PE3 ISOFORMIN II--------RLPTKMDTFPNIFP-PGGDSGLTSSQSEFQKVLIDERLRCEHHKTNYQTL RABIT4_75_PE4 ENSOCUG00000016919 ---------------MDTFPNIFP-PGGDSGLTSSQSEFQKVLIDERLRCEHHKTNYQTL RAT7_PE675 NOISO ---------------MDTFPSIFP-PGGDSRLNP-EPEFQSMLIDERVRCEHHKHNYQAL SORARGS_3223_PE2 NOISO ------------------------------------------------------------ SPETRGS_2549_PE2 NOISO ------------------------------------------------------------ TARSYGS_3736_PE2 NOISO VF--------GSFPQLGPFPNIFF-LGGEGGLPNFPFDSQK-KLDERFRCTS---KYQTL TETNG19_PE371 NOISO ---------------------------------GREGELQKMLIEERIHSENFRTKYYSL TUPGBGS_2489_PE2 NOISO ------------------------------------------------------------ TURTRGS_1422_PE2 NOISO VV--------SSLTNMDTFPTIFP-PGGDSGLTSSQSEFQKMLIDERLRCEHHKTNYQTL XENTR144_2_PE26 NOISO -------------------MEILPQMSSTLAVSAADTELQKLLIDEQMRCEHHKTNYQTL MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192861_1_1_PE2 NOISO KAEHTRI-RLQDEYIKSQHELKRLLKEKQTHQEKFQLLLEELRGELVEKTKDLEEMKLQ- ANOCA45_5_PE11 NOISO KAEHTR---LLDEYTKLQNELKQLLHEKQTVHEKFQLLLAELREELLAKTREIEELKMQ- CALJA9_90_PE1 NOISO KAEHTRI-RLQNEYVKLQNELKHLLNEKQIHQEKLQLLLQELREELVEKTKDLEEMKLQ- CANFA15_38_PE5 NOISO KAEHTRI-RLQDEYIKLQNELKRLLNEKQTHQEKFQLLLQELRGELVEKTKDLEEMKLQ- CAVPO9_7_PE5 NOISO KVEHTR---LQDEYIKSQNELKRLSNEKQTNQEKFQLMFEELREELLAKTKDLEELKGQ- CHICK1_PE561 NOISO KAEHIR---LQEEYTKSQDELKRLLVEKQTVHDKFQLLLAEYREELLGKTQELEKLKMQ- DANRE4_20_PE23 NOISO KVEHTR---LQDQYTRAQNELKRLLSDRQVTQEKQQLLLAELRGELLDKTRDLEELKLQK DASNOGS_3227_PE2 NOISO KAEHTRL---Q--------DEKRLLNEKQTHQEKFQLLLEELRGELVEKTKDLEEMKLQ- DIPORGS_3028_PE2 NOISO KGEHTR---LQNEYINSQNELKRLLNEKQTSQEHFRQLCEELKEQLVEKSKELEKAKLQ- ECHTEGS_9098_PE3 NOISO ------------------------------------------------------------ FUGRU168_PE55 NOISO KEETTR---LQDEFLQAQNEIRHLLSDKQTLQHQMKLQAADFQKSLLAKSKRLEELQQQ- FUGRU3595_PE2 NOISO ------------------------------------------------------------ GASACGROUPIV_23_PE9 NOISO KAEHAS---LQDEFTQAQGELKRLLSDRQTQQEKLQLLLAELRGDLLDKTRELEELRLQ- GORGO12_98_PE3 ENSGGOG00000026256 KAEHTRKNRLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQ- GORGO12_98_PE4 ISOFORMIN KAEHT---RLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQ- HORSE28_21_PE2 ENSECAG00000008428 KVEHTR---LQDEYIKSQNELKRLLNEKQTHQEKFQLLLEELRGELVEKTKDLEEMKLQ- HS12_PE1898 ENSG00000173588 KAEHT---RLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQ- HS12_PE1899 ISOFORMIN KAEHT---RLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQ- HS12_PE1900 ISOFORMIN KAEHT---RLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQ- LAMPAGS_1526_PE2 NOISO KTEHTR---LQDEYIKLQNELKRLLNEKQTHQEKFQQLLEELRGELVEKTKVLEEMKLQ- LOXAF2_91_PE3 NOISO KAEHTR---LQDEYIKSQNELKRLLNEKQTHQEKFQLLLQELREELVEKTKDLEEMKLQ- MACEUGS_4559_PE2 NOISO ------------------------------------------------------------ MACMU11_99_PE2 NOISO ------------------------------------------------------------ MICMUGS_1998_PE2 NOISO ------------------------------------------------------------ MONDO8_74_PE3 NOISO KAEHTR---LQNEYIKSQNELKQLLSEKQSLQEKFQLLLAELRGELVEKTKELEELKLQ- MOUSE10_PE1708 NOISO KIEHKR---LQEEYVKSQNELKRVLIEKQASQEKFQLLLEDLRGELVEKARDIEKMKLQ- MYOLUGS_2580_PE2 NOISO ------------------------------------------------------------ OCHPRGS_3935_PE2 NOISO ------------------------------------------------------------ ORNANULTRA443_9_PE18 NOISO KAEHTRKIRLQDEYTKSQNELKRLLNEKQTLQEKFQFLLAEVRGELLDKTKHLEELKMQ- ORYLA23_2_PE19 NOISO KAEHTS---LQDEFVRAQTELKRLLSDRQSLQEKTQLLQAELRGQLLDKSRELDQLRLK- OTOGAGS_2326_PE2 NOISO ------------------------------------------------------------ PANTR12_99_PE3 ENSPTRG00000005302 KAEHT---RLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQ- POEGU1A_46_PE9 NOISO RAEHLR---LQEDYTKSQDELKRLLVEKQAVHDKFQQLLADFQEQLLAKTQELEQVKQQ- PONPY12_100_PE2 NOISO KAEHT---RLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQ- PROCAGS_3333_PE2 NOISO KAEHTR---LQNEYMKSQNEIRRLLNEKQTHEEKFQLLLEELKEELLKKTTELEEMKPQ- PTEVAGS_1643_PE2 NOISO KAEHTR---LQDEYTKSQNELKRLLIEKQRNQEKLQLLLEELRGELVEKTKDLEEMKMQ- RABIT4_75_PE3 ISOFORMIN KAEHT---RLQDEYMKSQNELKRLLSEKQTNQEKFQLLLEELRGELVQKTKDLEEMKLR- RABIT4_75_PE4 ENSOCUG00000016919 KAEHTRT-RLQDEYMKSQNELKRLLSEKQTNQEKFQLLLEELRGELVQKTKDLEEMKLR- RAT7_PE675 NOISO KIEHKR---LQEEYVKSQNELKRVLNEKQTNQEKFQLLLEELRGELVEKVKDMEAMKLQ- SORARGS_3223_PE2 NOISO ------------------------------------------------------------ SPETRGS_2549_PE2 NOISO ------------------------------------------------------------ TARSYGS_3736_PE2 NOISO KEH-T---KLQNEYMKLQNELRRLSNEKQTYQEKLQLMLEELRGELVEKVNHLEEMKQQ- TETNG19_PE371 NOISO KEETTR---LQEEFIQAQDEIKHLLSDRQSLQDTMSLQMVELQRSLLAKTKEAEELRQQ- TUPGBGS_2489_PE2 NOISO ------------------------------------------------------------ TURTRGS_1422_PE2 NOISO KAEHTR---LQDEYIKSQNELKRLLNEKQTHQEKFQLLLEELRGELVEKTKDLEEMKLQ- XENTR144_2_PE26 NOISO KAEHTR---LQDEYIKSQNECKRLLMEKQNTQEKVQLMLAELRGELLDKTREAEELKLK- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192861_1_1_PE2 NOISO VLTPQKLELL-------RAQIQQELETPVRERFRNLDEEVEKYRTEYNKLRYEHTFLKSE ANOCA45_5_PE11 NOISO VITPQKLELL-------KVQIQQDLETPMRERFRKLDEEVEKYRAEYNKLRYEHTFLKSE CALJA9_90_PE1 NOISO ILTPQKLELL-------RAQIQQELETPMRERFRTLDEEVEKYRAVYNKLRYEHTFLKSE CANFA15_38_PE5 NOISO VLTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRSEYNKLRYEHTFLKSE CAVPO9_7_PE5 NOISO VLNRQNLELL-------RAQIQQELETPMRERCRNLDEEAEKYRTEYNKLRYEHTFLKSE CHICK1_PE561 NOISO VLTPQKLELL-------KAQIQQELESPMAERYRKLENEMEKYRTEYNKLRYEHTFLKSE DANRE4_20_PE23 NOISO VLTPQRLELL-------RAQVQQELEAPIRERFNKLQEEAENYRSEYNKLRYDLTFLKSE DASNOGS_3227_PE2 NOISO XXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXEVEKYRAEYNKLRYEHTFLKSE DIPORGS_3028_PE2 NOISO VLNPQHLELL-------KAQIQQELEAPMREHFQNLDQEVEKYRAEYNKLRYEHTFLKSE ECHTEGS_9098_PE3 NOISO --------------------------------------EVEKYRSEYNKLRYEHTFLKSE FUGRU168_PE55 NOISO TMSPLQQEML-------KAQMQQEMDAPVREMRLQLEEEIEKYKAEYYKLRYECLRLQSQ FUGRU3595_PE2 NOISO -------------------------------------QEIEKYKAEYYKLRYECLRLQSQ GASACGROUPIV_23_PE9 NOISO VMTPQRLELL-------RAQVQQEMEAPVRERFNKLEEETEKYRSEYNKLRYEFTFLKSQ GORGO12_98_PE3 ENSGGOG00000026256 ILTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSE GORGO12_98_PE4 ISOFORMIN ILTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSE HORSE28_21_PE2 ENSECAG00000008428 VLTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAEYNKLRYEHTFLKSE HS12_PE1898 ENSG00000173588 ILTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSE HS12_PE1899 ISOFORMIN ILTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSE HS12_PE1900 ISOFORMIN ILTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSE LAMPAGS_1526_PE2 NOISO VLTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAGYNKLRYEHTFLKSE LOXAF2_91_PE3 NOISO VLTPQKLELL-------RAEIQQELETPMRERFRNLDEEVEKYRAEYNKLRYEHTFLKSE MACEUGS_4559_PE2 NOISO VLTPQKLELL-------RTEIQQELETPMRERFRNLDEEAEKYRGEYNKLRYEHTFLKSE MACMU11_99_PE2 NOISO ----------------------------MRERFRNLDEEVEKYRAAYNKLRYEHTFLKSE MICMUGS_1998_PE2 NOISO --------------------------------------EVEKYRAEYNKLRYEHTFLKSE MONDO8_74_PE3 NOISO VLTPQKLELL-------RTQIQQELETPMRERFRNLDEEVEKYRAEYNKLRYEHTFLKSE MOUSE10_PE1708 NOISO VLTPQKLELV-------KAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEYTFLKSE MYOLUGS_2580_PE2 NOISO ----------------------------MRERFRSLDEEVEKYRAEYNKLRYENTFLKSE OCHPRGS_3935_PE2 NOISO VLTPQKLELL-------RTEIQQELEAPMRERFRTLDEEVEKYRAEYNKLRYEHTFLKSE ORNANULTRA443_9_PE18 NOISO VLTPQKLELL-------KAQIQQESEALMRERFQNLDEEVEKYRAEYNKLRYEHTLLKSE ORYLA23_2_PE19 NOISO VMTPERLELL-------RAQVQQEMEAPVRERFNKLEEEAEKYRSEYNKLRYDYTFLQSQ OTOGAGS_2326_PE2 NOISO ----------------------------MRERFHNLDEEVEKYRAEYNKLRYEHTFLKSE PANTR12_99_PE3 ENSPTRG00000005302 ILTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSE POEGU1A_46_PE9 NOISO VLTPQKLERL-------KAKIYEELESPMRERYQKLENEVEKYRTLYNKLRYDHTFLKSE PONPY12_100_PE2 NOISO ILTPQKLELL-------RAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSE PROCAGS_3333_PE2 NOISO VLTPQKLELL-------RAEIQQELETPMRERFRNLDEEVEKYRAEYNKLRYEHTFLKSE PTEVAGS_1643_PE2 NOISO XXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXEVEKYRAEYNKLRYEHTFLKSE RABIT4_75_PE3 ISOFORMIN VLTPQKLESL-------RAEIRQELETPMRERFRNLDEEVEKYRAEYNKLRYEHTFLKSE RABIT4_75_PE4 ENSOCUG00000016919 VLTPQKLESL-------RAEIRQELETPMRERFRNLDEEVEKYRAEYNKLRYEHTFLKSE RAT7_PE675 NOISO ILTPQKLELV-------KAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEHTFLKSE SORARGS_3223_PE2 NOISO ----------------------------MREQFRNLDEEVEKYRAEYNKLRYEHTFLKSE SPETRGS_2549_PE2 NOISO ----------------------------MRERLRNLDEEVEKYRAEYNKLRYEHTFLKSE TARSYGS_3736_PE2 NOISO ILTPQKLELL-------RAQIQQELETPMRERFQNLDEEVEKYRADYNKLRYEHTFLKSE TETNG19_PE371 NOISO TMSPLQQEMLKVEQEMLKAGLQQEINLLLREMCRQLEEEVEKYRSGYNQVRYECIGLQSQ TUPGBGS_2489_PE2 NOISO ----------------------------MKERFRNLDEEVEKYRAEYNKLRYEHTFLKSE TURTRGS_1422_PE2 NOISO VLSPQKLELL-------RAEIQQELETPMRECFRHLDEEVEKYRAEYNKLRYEHTFLKSE XENTR144_2_PE26 NOISO VLSPQKLELL-------KIQILEEQEAPIKERYRQLEEEAEKYRGDYNKLRYELTLLRAE MATCH * *.*: * ::**: *::: CONSENSUS ?????????????????????????????RE????L?EEVEKYR??YNKLRYEHTFLKSE

AILMEGL192861_1_1_PE2 NOISO FEHQKEEFARILEEEKIKYESEIASLEKDKEELHNQQLKVDPGKDSKRIEQLVREKLHLS ANOCA45_5_PE11 NOISO FEHQREEHARILEENKLKYESEITRLDKDKEELHNQLLSVDPTRDNKRVETLLREKTHLL CALJA9_90_PE1 NOISO FEHQKEEFARVLEEGKIKYQSEIARLEEDKEELRNQLLNGDLTRDSKRVEQLTREKVYLH CANFA15_38_PE5 NOISO FEHQKEEHARILEEEKIKYESEIARLEKDKEEIHNQLLSVDPTKDSKRMEQLVREKVHLS CAVPO9_7_PE5 NOISO FEHQKEEFARILEEEKMKHESEVARLEKDKEELHSRLLAVDPTRHMKRVEQLLQEKAHLG CHICK1_PE561 NOISO FEHQKEEHEHVLEEEKIKYEAEIARLEKDKEELHNQLVSVDPTRDSKRVEVLSREKAQLC DANRE4_20_PE23 NOISO FDHQKEEHARVLEERRIRHEADVARLEHDKEDLATQLQSGDPARDGKRVEALLREKAQLH DASNOGS_3227_PE2 NOISO FEHQKEEFSRILEEEKIKYESEIARLEKDKEELHNQLLSVDPTRDSKRVEQLVREKVHLC DIPORGS_3028_PE2 NOISO FEHQKEEFVRISQEEKMKYESEVARLERDKEELHNQLLKVDLTKDSKRMEQLVREKTHLC ECHTEGS_9098_PE3 NOISO FEHQKAECSRILQEEKIKYESEVARLEKDKEELYNQLFSTDPTKESRRVEQLTREKVHLC FUGRU168_PE55 NOISO ADQQREEHARALESQRLRYQAEMSCLEADKEALAARLQSSDQRSNDKKLEALMKERVQLK FUGRU3595_PE2 NOISO ADQQREEHARALESQRLRYQAEMSCLQTDKEALAARLQSSDQRSNDKKLEALMKERVQLK GASACGROUPIV_23_PE9 NOISO FDHQREEHAHTLEERRLRYEAEISRLEKDREDLMAHYQGSDQLRDGKRVEALLREKTQLH GORGO12_98_PE3 ENSGGOG00000026256 FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC GORGO12_98_PE4 ISOFORMIN FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC HORSE28_21_PE2 ENSECAG00000008428 FEHQKEEFARILEEEKIKCESEIARLEKDKEELHNQLLSVDPTRDSKRMEQLVREKVHLC HS12_PE1898 ENSG00000173588 FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC HS12_PE1899 ISOFORMIN FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC HS12_PE1900 ISOFORMIN FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC LAMPAGS_1526_PE2 NOISO FEHQKEKARXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXEQLVRKKVHLC LOXAF2_91_PE3 NOISO FEHQKEEFGRILEEEKIKNESEIARLEKDKEELHNQLLSVDPTRDSKRVEQLVREKVHLC MACEUGS_4559_PE2 NOISO FEHQKEEYMRILEEQKIKYDAEVSRLEKDKEEIHNQLLNIDPTRDSKRVEKLVREKAQLC MACMU11_99_PE2 NOISO FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTRDSKRVEQLAREKVYLC MICMUGS_1998_PE2 NOISO FEHQKEEFAHILEEEKIKYESEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MONDO8_74_PE3 NOISO FEHQKEEYMRILEEMKIKYEAEVTRLEKDKEEVHNQLLNVDPTKDSKRVEKLIREKVQLC MOUSE10_PE1708 NOISO FEHQKEEFTRVSEEEKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRMEQLVREKTHLL MYOLUGS_2580_PE2 NOISO FEHQKGEFARTLEEEKIKYESEIARLEKDKEELRNQLLSLDPTRDSKRVQQLTREKVHLA OCHPRGS_3935_PE2 NOISO FEHQKEEFARILEEEKIKYESEIARLEKDKEELHSQLLSVDPAKDSKRVEQLIGEKVRLC ORNANULTRA443_9_PE18 NOISO FEHQKEEHAHILEEKKIKYESEIARLDRDKEELHNQLLSVDPIRENKRIEKLLREKAQLY ORYLA23_2_PE19 NOISO WEQQREEHSRVLEERRICYEAEIARLEKDREELMAQRRDSDRLQDGQRVEALLREKAQLH OTOGAGS_2326_PE2 NOISO FEHQKEEFAHILEEEKIKHEAENVRLEKDKEELRTLYLLSDLTRDSKRVEQLVREKVQLC PANTR12_99_PE3 ENSPTRG00000005302 FEHQKEEYARILDEGKIRYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC POEGU1A_46_PE9 NOISO FEHQKEEHAHILEEKKIKYEAEIARLDKDKEELHNQLLSIDPTRDSKRVEALSREKAQLC PONPY12_100_PE2 NOISO FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC PROCAGS_3333_PE2 NOISO FKHQKEQYERILEEEKIKHESEIARLEEDKEELYKKLVSVNSTGDSKQAEKLVQEKVHLC PTEVAGS_1643_PE2 NOISO FEHQKEEFARILGEEKIKYESEIVRLEEDKEELHKQLLSVDPTRDSKRTEQLLREKVQLC RABIT4_75_PE3 ISOFORMIN FEHQKEEFARVLEEEKIKHESEIARLEKDKEELHNQLLSVDPAKDSKQVEQLIGEKVRLC RABIT4_75_PE4 ENSOCUG00000016919 FEHQKEEFARVLEEEKIKHESEIARLEKDKEELHNQLLSVDPAKDSKQVEQLIGEKVRLC RAT7_PE675 NOISO FEHQKEELTRISEEEKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRVEQLVREKTHLL SORARGS_3223_PE2 NOISO FEHQKEEFARLLEEEKIKYESEIARLEKDKEELHKQLLSVDPSRESKRIQQLIQDKLHLC SPETRGS_2549_PE2 NOISO FEHQKEEFARISEEEKIKYESEIARLEKDKEELHNQLFSVDLTRDTKRMEQLVREKVHLS TARSYGS_3736_PE2 NOISO FEHQKEESARILEEEKIKYESKIARLEEDKEELRQQLFAVDPTRDSKRAEQLLQEKVHLC TETNG19_PE371 NOISO LEQQRGEHAHGLESQRLLHQAETSVLQKDKEELVARLQGFLLRSDEKKLEALLKERVQLK TUPGBGS_2489_PE2 NOISO FEHQKEEFARILEEEKIKYESEVARLEKDKEELHNQMLSVDPTRDSKRVEQLMREKVHLC TURTRGS_1422_PE2 NOISO FEHQKEECARILEEEKIKYESEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XENTR144_2_PE26 NOISO FDHQKEEHERVLQERRIKYEAEILQLEREKKELHDQIMSVDPTRDSKRVEVLLREKAQLY MATCH .:*: : CONSENSUS FEHQKEE??R?L?E?K?K?E?E??RLE?DKEEL???L???D???D?KR?E?L??EK??L?

AILMEGL192861_1_1_PE2 NOISO QKLKSLEAEVAELRAEKENSGAQVENVQRTQVRQLAEMQATVRSLE--AEKQSAKLQAER ANOCA45_5_PE11 NOISO QKVKGLEAEVAEIRAQREDSSVQADNVQRLQLRQLAEMQGTIRSLE--AEKQSVKLLLER CALJA9_90_PE1 NOISO QKLKGLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQTTVRSLE--AEKQSAKLRAEH CANFA15_38_PE5 NOISO QKLKGLEAEVAELRAEKENFGAQVENVQRIQVRQLAEMQATVRSLE--AEKQSAKLQAER CAVPO9_7_PE5 NOISO QKLKGLETEVAELRAEKENSGAQVESVQRIQVRQLAEMQATVRSLE--AEKQSVKLQAER CHICK1_PE561 NOISO QKLKGLEAEVAELRAERDNCGVQAENVQRVQVRQLAELQSLARSLE--AEKKSAEQHIGR DANRE4_20_PE23 NOISO QRLRGLEAEVTELRAERNNSGAQAENVQRIQIRQLAESQAAVKALE--AEKQSIRMQLDR DASNOGS_3227_PE2 NOISO QKLKGLETEVAELRTEKENSGTQVENVQRIQVRQLAEMQATVRSLEXXXXXXXXXXXXXX DIPORGS_3028_PE2 NOISO QKLKSLEAEIAELRAEKENSGAQVENVQRIQVRQLAEMQATVRSLE--AEKQSAKLQAER ECHTEGS_9098_PE3 NOISO QKLKGLETEVAELRAEKENSGAQVESVQRIQVRQMADMQATVRSLE--XXXXXXXXXXXX FUGRU168_PE55 NOISO VRIQGLEAEVAELLAQKESLSQQAEKTQSIQNRRLTESQAALKSLE--AERESVRLQLEK FUGRU3595_PE2 NOISO VRIQGLEAEVAELLAQKESLSQQAEKTQSIQNRRLTESQAALKSLE--AERESVRLQLEK GASACGROUPIV_23_PE9 NOISO LRLKGLETEMAELRAQKDNSGQQADSVQRIQIRQLTESQSAVKSLE--AERQSLRLQLER GORGO12_98_PE3 ENSGGOG00000026256 QKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLE--SDYFQGKLRAER GORGO12_98_PE4 ISOFORMIN QKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLE---------LRAER HORSE28_21_PE2 ENSECAG00000008428 QKLKGLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATVRSLE--AEKQSAKLQAER HS12_PE1898 ENSG00000173588 QKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLE--AEKQSANLRAER HS12_PE1899 ISOFORMIN QKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLE--AEKQSANLRAER HS12_PE1900 ISOFORMIN QKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLE--AEKQSANLRAER LAMPAGS_1526_PE2 NOISO QEIKGLQAEVEEGGVKKENFGVQVESAQRIQVRQLVEMQIPFRSLD--AEKQSAKLQAER LOXAF2_91_PE3 NOISO QKLKGLEAEVAELRAEKENSGAQVESVQRIQVRQLAEMQATVRSLE--AEKQSAKLQSER MACEUGS_4559_PE2 NOISO QKLKGLEAEVTELRAERENFGTQAENVQRIQVRQLAEMQATVRSLE--AEKQSAKLQYDR MACMU11_99_PE2 NOISO QKLKGLEAEVAELRAEKENSDAQVENAQRIQVRQLAEMQATVRSLE--AEKQSANLRAER MICMUGS_1998_PE2 NOISO XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAEKQSAKLQAER MONDO8_74_PE3 NOISO QKLKGLEAEVTELRAERENCGIQAENVQRIQVRQLAEMQATVRSLE--AEKQSAKLQYDR MOUSE10_PE1708 NOISO QKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLE--AEKQSAKLQAER MYOLUGS_2580_PE2 NOISO QKLKELEAEVAELRAEKENSDARVENVQRIQVQQLAGMQATIRSLE--AEKQSVKLHVER OCHPRGS_3935_PE2 NOISO QKLKCLETEVAELRAEKENSGAQAENIQRIQVRQLAEMQATVRSLE--AEKQSAKLQAEH ORNANULTRA443_9_PE18 NOISO QKLKGLDAEVAELRAERENSGAQLENVQRIQVRQMTEMQATLRSLE--AEKQSAKQQSDR ORYLA23_2_PE19 NOISO LRMRGLEAEVAELRALKENSGQQAESVQRIQTRQLTESQAAVKSLE--AERQSLRLQLER OTOGAGS_2326_PE2 NOISO QKLKGLEAEVTELRAEKENSDAQVESAQRIQVRQLAEMQATIRSLEXXXXXXXXXXXXXX PANTR12_99_PE3 ENSPTRG00000005302 QKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLE--AEKQSANLRAER POEGU1A_46_PE9 NOISO QKLKALEAEVEELRAERHNCVVQAENVQRVQARQLAEMQTMMRSLE--AEKKSAELQVDR PONPY12_100_PE2 NOISO QKLKGLEAEVVELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLE--AEKQSANLRAER PROCAGS_3333_PE2 NOISO QILKGLEAEVAELRAEKENSVAQV-STQRIQVRQLAEMQATVRSLE--AEKQSAKLQSER PTEVAGS_1643_PE2 NOISO QKLKGLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLE--AEKQSAKLQAER RABIT4_75_PE3 ISOFORMIN QKLKCLETEVAELRAEKENSGAQVENIQRIQVRQLAEMQATVRSLE--AEKQSAKLHAEH RABIT4_75_PE4 ENSOCUG00000016919 QKLKCLETEVAELRAEKENSGAQVENIQRIQVRQLAEMQATVRSLEQKAEKQSAKLHAEH RAT7_PE675 NOISO QKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLE--AEKQSAKLQAER SORARGS_3223_PE2 NOISO QKLKSLEEEVAELRAEKENSGAQVESVQRIQVRQLAEMQATVRSLE--AEKQSAKLQTEH SPETRGS_2549_PE2 NOISO QKLKGLEAEVAELRAEKENSGAQIENVQRIQVRQLAEMQATVRSLE--AEKQSAKLQAER TARSYGS_3736_PE2 NOISO QKLKDLTAEVAELRAEKENSGAQIESVQRIQVRQLTEMQATVRSLEAKQ---SAQLXXXX TETNG19_PE371 NOISO VRLQGLEAEVAELHAQKESLSQQAENAQSVQNRQLTESQALLKSLE--AERESMRLQLEK TUPGBGS_2489_PE2 NOISO QKLKGLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATMRSLE--XXXXXXXXXAEH TURTRGS_1422_PE2 NOISO XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAEKQSAKLQAER XENTR144_2_PE26 NOISO QKLKSLEAETTELRAERENYGSQAENVQRIQVRQMAENQATIRSLE--AEKQSMKLQLER MATCH CONSENSUS Q?LK?LE?EV?EL?AE?EN???Q?E??QRIQ?RQL?E?QA??RSLE??AE??S??L????

AILMEGL192861_1_1_PE2 NOISO LEKELQSSSEQNTVLISKLHKAEREVNTLTSKVKELKHSNKLEITDIKLEAARAKSELER ANOCA45_5_PE11 NOISO VEKELQMSNEQNTLLTGKLHKAEREINGLATKVEELKHSHKLEVTNIKLESARARSEIER CALJA9_90_PE1 NOISO LEKDLQSSNEQNTCLINKLHKAEREINSLSSKVKELKHSNKLEITDIKLEAARAKSELEK CANFA15_38_PE5 NOISO LEKELQSSSEQNTVLISKLHKAEREINTLTSNVKELKHSNKLEITDIKLEAARAKSELER CAVPO9_7_PE5 NOISO LEKELQSTSEQNMSLISKLHKADQEISTLTSTIKELKHSKKLEITDIKLEAARAKSELER CHICK1_PE561 NOISO IEEELQMCREQNFLLTSKLHKSEQEVNSLAAKVEELKQSHKLEVTNVKLEAARTKNEVER DANRE4_20_PE23 NOISO TESELRLSQEQNTLLTGKLHKAEREINSLNSQVEEMKHTHKLELSNVKLECVRSKGELER DASNOGS_3227_PE2 NOISO XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXVKELKHSNKLEITDIKLEAARAKSELER DIPORGS_3028_PE2 NOISO LEKELQSSNEQNTCLISKLHKADREINTLTSKVKELKHSNKLEITDIKLEAARAKSDLER ECHTEGS_9098_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX FUGRU168_PE55 NOISO MQKELHLSNEESCQLTKRLHGAERQVTSLTCQVESLKFSHKQEVNNIKLEFTLSQGELEK FUGRU3595_PE2 NOISO MQKELHLSNEESCQLTKRLHGAERQVTSLTCQVESLKFSHKQEVNNIKLEFTLSQGELEK GASACGROUPIV_23_PE9 NOISO MGSELHLTHEQNSQLSGRLNKAEREVNSLTSQIDSLKHSHKLEAASIKLECARSKGELER GORGO12_98_PE3 ENSGGOG00000026256 LEKELQSSSEQNTFLINKLHKAEREINTLSSKVFHFQNANKISIIVVSLKMSSHFSKFQG GORGO12_98_PE4 ISOFORMIN LEKELQSSSEQNTFLINKLHKAEREINTLSSK---------------------------- HORSE28_21_PE2 ENSECAG00000008428 LEKELQSSSEQNTVLISKLHKAEREINTLTSKVKELKHSNKLEITDIKLEAARAKSELER HS12_PE1898 ENSG00000173588 LEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELER HS12_PE1899 ISOFORMIN LEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELER HS12_PE1900 ISOFORMIN LEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELER LAMPAGS_1526_PE2 NOISO L-KELQSSNEQNTTLISKLHKAEREINTL---VKELKHSSKLEITDIRLEAARAKSELER LOXAF2_91_PE3 NOISO LEKELQSSNEQNTLLISKLHKAEREVNTLTSKVKELKHSNKLEITDIKLEAARAKSELER MACEUGS_4559_PE2 NOISO VEKELQSTNEQNTLLISKLHKAEREVTSLTSKXXXXXXXXXXXXXXXXXXXXXX-XXXXX MACMU11_99_PE2 NOISO LEKELQSSSEQNTFLINKLHKAEREVNTLSSKVKELKHSNKLEITDIKLETARAKSELER MICMUGS_1998_PE2 NOISO LEKELQSSSEQNTFLNSKLHKAEREISTLTST-------AKLEITALKLGAARVRSEVVK MONDO8_74_PE3 NOISO VEKELQSTNEQNTLLISKLHKAERETTALTSEVQELKHSNKLEIADIKLEAARAKSEIER MOUSE10_PE1708 NOISO LEKELQSSNEQNTCLISKLHRADREISTLASEVKELKHANKLEITDIKLEAARAKSELER MYOLUGS_2580_PE2 NOISO LEKELQSSNEQNTVLITKLHKAEREINALSSKXXXXXXXXXXXXXXXXXXXXX-XXXXXX OCHPRGS_3935_PE2 NOISO LEKELQSNSEQNTLLIGQLHKAERDINTLTSQVKELKHSNKLEITDIKLEAARAKSELER ORNANULTRA443_9_PE18 NOISO MEKELQSANEQNTLLISKLHKAEREINEWNRKVEELKHSSKLEITDIKLEAARAKSEIER ORYLA23_2_PE19 NOISO TEGELHQSLEQSDQLTGRLHKAEREVSALSCQMESLKHSHKLEVDRVRLECARSKAELER OTOGAGS_2326_PE2 NOISO XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXVKELKHSNKLEITDIKLEAARAKSELER PANTR12_99_PE3 ENSPTRG00000005302 LEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELER POEGU1A_46_PE9 NOISO IEKELQTSHEQNILLTSKLHKCEREVNSLTAQVKELKHSHKLEVTNVKLEAARTKSEIER PONPY12_100_PE2 NOISO LEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELER PROCAGS_3333_PE2 NOISO LEKELQSSSEQNTLLISKLFKAEREVNILTSKVKELKHSNKLEITDIKLEAARAKSELER PTEVAGS_1643_PE2 NOISO LERELQSSNEQNTVLISKLHKAEREINTLTSKVKELKHSNKLEITDIKLEAARAKSELER RABIT4_75_PE3 ISOFORMIN LEKELQSNSEQNTLLISKLHKAEGEITTLTSKVKELKHSNKLEITDIKLEAARAKSELER RABIT4_75_PE4 ENSOCUG00000016919 LEKELQSNSEQNTLLISKLHKAEGEITTLTSKVKELKHSNKLEITDIKLEAARAKSELER RAT7_PE675 NOISO LEKELQSSNEQNTCLISKLHKADREISTLTSQVKELKHANKLEITDVKLEAARAKSELER SORARGS_3223_PE2 NOISO LEKELQSSNEQNTILITKMHKAEREINTLASQVKELKHSNKLEITDIKLEAARAKSELER SPETRGS_2549_PE2 NOISO LEKELQSSNEQNTFLTSKLHKADREINTLTSKXXXXXXXXXXXXXXXXXXXXXXXXXXXX TARSYGS_3736_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVKELKHSNKLEITDIKLEAARAKSELER TETNG19_PE371 NOISO VREELELSNEENCQLSRQLHGAERQVSSLTCQIENLRFSHKQEVNSIKVDFTLSQGELEK TUPGBGS_2489_PE2 NOISO L-EELQSSSEQNTVLISKLHKAEREINTLTSKVKELKHSNKLEITDIKLEAARAKSELER TURTRGS_1422_PE2 NOISO LEKELQSSNEQNTTLISKLHKAEREINTLTSKVKELKHSNKLEITDIKLEAARAKSELER XENTR144_2_PE26 NOISO LEKELHESTEQNTILTAKLHKMEREVNALSSRTGELKYSHKMEISNIKLEAAKTKNEVER MATCH CONSENSUS ???EL????EQN??L???LHKAERE???L??????LK???K?E????KLE??????E?E?

AILMEGL192861_1_1_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-SAVEHHKALLVEKDRELIRKVQAAKEEGYQKLVVL ANOCA45_5_PE11 NOISO ER-NKIQSEMD---GLRSDNEILK-TTLERHKVILTEKDRELIRKVQAAKEEEFQKLAML CALJA9_90_PE1 NOISO ER-NKIQSELD---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL CANFA15_38_PE5 NOISO ER-NKIQSELD---GLQSDNEILK-SAVEHHKALLVEKDRELIRKVQAAKEEGYKKLVVL CAVPO9_7_PE5 NOISO ER-NKIQSELD---GLQSDNEILK-SAVEHHKTLLVEKDRELVRKVQAAKEEGYQKLVVL CHICK1_PE561 NOISO ER-NKIQSEMD---GLLSDKEVLK-EAVERHKVLLVEKDQELVRKVQAAKEEVFGKIAAL DANRE4_20_PE23 NOISO ER-DMLQCQVE---GLQSDIEVMK-SALERNKELISEKEREMVRRVQAAREEEIHKMATL DASNOGS_3227_PE2 NOISO ER-NKIQSELD---GLQADNEILK-SAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVAI DIPORGS_3028_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-SAIEHHKMVLVEKDRELIRKVQAAKEEGYQKLVLL ECHTEGS_9098_PE3 NOISO XX-XXXXXXXX---XLQSDNEVLK-SAVEYHKVLLVEKDRELIRKVQAAKEEGYQKLVAL FUGRU168_PE55 NOISO ER-NKLQALIE---GFQTEVELLR-AEITQLKAALVEKEREMCRKVQSVRDEEFRRTVEL FUGRU3595_PE2 NOISO ER-NKLQALIE---GKTQLRE------------VLMEKEEEMCRKVHWVHEEGLHKAAQV GASACGROUPIV_23_PE9 NOISO ER-DALHGQID---GLQADMEVLK-AAVERHKDVLVEKERELVRKVQSAREEEFHKIATL GORGO12_98_PE3 ENSGGOG00000026256 EMNKKVKKKTL---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL GORGO12_98_PE4 ISOFORMIN ---------------LQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL HORSE28_21_PE2 ENSECAG00000008428 ER-NKIQSELD---GLQSDNEILK-SAVEHHKTLLVEKDRELIRKVQAAKEEGYQKLVVL HS12_PE1898 ENSG00000173588 ER-NKIQSELD---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL HS12_PE1899 ISOFORMIN ER-NKIQSELD---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL HS12_PE1900 ISOFORMIN ER-NKIQSELD---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL LAMPAGS_1526_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-SAVEHHKVLLVEKDRELIRKVQAARDEGYQKLVVL LOXAF2_91_PE3 NOISO ER-NKIQSELD---GLQSDNEILK-SAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVAL MACEUGS_4559_PE2 NOISO XXXXXXXXXXX---XLQSDNE-LK-SAIERYKTLLLEKDRELVRKVQAAKEEGYQKLAAL MACMU11_99_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL MICMUGS_1998_PE2 NOISO ET-NQLQSALD---GLQSDNEILK-SAVEHHKALLVEKDRELIRKVQAAKEEGYQKLVVL MONDO8_74_PE3 NOISO EK-NKIQSQVD---GLQSDNEILK-SAIERHKMLLLEKDRELVRKIQAAKEEGYQKLAAL MOUSE10_PE1708 NOISO ER-NKIQSELD---GLQSDNEILK-STVEHHKALLVEKDRELIRKVQAAKEEGYQKLMVL MYOLUGS_2580_PE2 NOISO XXXXXXXXXXX---XLQSDNEILK-SAVEQHKVLLAEKDRELIRKVQAAKEEGYQKLVVL OCHPRGS_3935_PE2 NOISO ER-NKIQSELN---GLQSDNEILT-SAVEHHKMLLVEKDRELIRKVQAAKEEGYQKLAVL ORNANULTRA443_9_PE18 NOISO ER-NKIQSQMDEKTVLQSDSEILK-STVERQKMLLVEKDRELIRKVQAAKEDGFQKLAAL ORYLA23_2_PE19 NOISO ER-DTLQGQND---GLQTDVEVLK-AAVSRSKEVLMEKERDAVKRVQSAREEEQRRTAAL OTOGAGS_2326_PE2 NOISO XXXXXX----XXXXXSQSDNEILK-STIEHHKMLLVEKDRELIRKVQAAKEEGYQKLVVL PANTR12_99_PE3 ENSPTRG00000005302 ER-NKIQSELD---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL POEGU1A_46_PE9 NOISO ER-NKIQSEMD---GLLSDKEILT-AAVERHKVLLVEKDRELIRKVQAAKEEVFDNIAAL PONPY12_100_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-AAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL PROCAGS_3333_PE2 NOISO ER-NKIQSELD---GLQSDNVILK-SAVEHHKALLVEKDRELIRKVQAAKEEGYQKLVAV PTEVAGS_1643_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-SAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVAL RABIT4_75_PE3 ISOFORMIN ER-NKIQSELD---GLQSDNEILT-SAVEHHKMLLVEKDRELIRKVQAAKEEGYQKLVAL RABIT4_75_PE4 ENSOCUG00000016919 ER-NKIQSELD---GLQSDNEILT-SAVEHHKMLLVEKDRELIRKVQAAKEEGYQKLVAL RAT7_PE675 NOISO ER-NKIQSELD---GLQSDNEILK-STVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL SORARGS_3223_PE2 NOISO ER-NRIQSELD---GLQSDNEILK-STVEHHKMLLVEKDRELVRKVQAAKEEGYQKLVVL SPETRGS_2549_PE2 NOISO XX-XXXXXXXX---XLQSDNEILK-SAVEYHKVLLVEKDRELIRKVQAAKEEGYQKLVVL TARSYGS_3736_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-SAVEHHKMLLVEKDRELIRKVQATREEGYQKLVAL TETNG19_PE371 NOISO ER-NKLQGQIE---GGSHLTEIITRSNVIAPPVLLHLFEREMCRKVQSVRDEEFRKTVQL TUPGBGS_2489_PE2 NOISO ER-NKIQSELD---GLQSDNEILK-SAIEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL TURTRGS_1422_PE2 NOISO ER-NKIQSELD---GLQSDNEILT-SAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVL XENTR144_2_PE26 NOISO ER-DKVQSQLD---VMQTENGILK-ATLDRQKEILAEKDRELIRKVQAAKEAGFQQIVTL MATCH : :.: :::: .:: . : CONSENSUS ER????Q???????GLQSDNEILK????E?HK?LLVEKDREL?RKVQAAKEEG?QKL??L

AILMEGL192861_1_1_PE2 NOISO QDEKIELENRLADLEKMKVEHDVWRQSEKDQCEEKLRASQMAEESARRELQSIRLKLQQQ ANOCA45_5_PE11 NOISO QEEKLELETTLAELKKEIVEQDTQKQSQKDQYEKKLSTLQLAEESSKREIQNLRLKLQQQ CALJA9_90_PE1 NOISO QDEKLELENKLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSI------- CANFA15_38_PE5 NOISO QDEKIELENRLADLEKMKVERDVWRQSEKEQCEEKLRASQMAEESARRELQSIRLKLQQQ CAVPO9_7_PE5 NOISO QDEKLELENRLADLEKMKVEHDIWRQSEKDQHEEKLRASQMAEEAARRELQSIRLKLQQQ CHICK1_PE561 NOISO QDEKLELESRLAHLEKVKLEQDAWRQTEKDQYEEKLRVVQLAEESSKRELQCLRLKIQQQ DANRE4_20_PE23 NOISO QEEKLELENRLSELEQQKALQEVTGNSQKEEWEERLRAAQLGEESVRKELQNLRTKVQQQ DASNOGS_3227_PE2 NOISO QDEKLELENRLADLEKTKVEHDVWRQSEKNECEEKLRASQXXXXXXXXXXXXXXLKLQQQ DIPORGS_3028_PE2 NOISO QDEKLELENKLADLEKMKVEHDVWRQSEKDQCEEKLRAAQMSEESARRELQSIRLKLQQQ ECHTEGS_9098_PE3 NOISO DEXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXLKLKQQ FUGRU168_PE55 NOISO QEEKLELEHHLSSMQQQTSLKEAAAREQMADWEERLSSAKLREESASGELQRLRTELQQQ FUGRU3595_PE2 NOISO QKERLELEKHMTQ-------TDAAVKDQLGKWLECLNQAKHREESMSKELKDLRTELQQQ GASACGROUPIV_23_PE9 NOISO HEEKLEVENRLASLEQQRALQVAADHSQKEEWEERLRISQQGEESVRRELQNLRSKLQQQ GORGO12_98_PE3 ENSGGOG00000026256 QDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMTEEITRKELQSVRLKLQQQ GORGO12_98_PE4 ISOFORMIN QDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMTEEITRKELQSVRLKLQQQ HORSE28_21_PE2 ENSECAG00000008428 QDEKLELENRLADLEKMKVEHDVWRQSEKDQCEQKLRASQMAEESARRELQSIRLKLQQQ HS12_PE1898 ENSG00000173588 QDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQ HS12_PE1899 ISOFORMIN QDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQ HS12_PE1900 ISOFORMIN QDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQ LAMPAGS_1526_PE2 NOISO QDEKLELESRLADLEKMKVEHDVWRQSERDQCEEKLRASQMAEESARRELQSIRLKLQQQ LOXAF2_91_PE3 NOISO QDEKLELENRLADLEKMKVEHDVWRQSEKDQCEEKLRASQMAEESARRELQSIRLKLQQQ MACEUGS_4559_PE2 NOISO QDEKLELENKLADLEKTKVEQDVWRQSEKDQCEEKVRVSQMAEEVAKRELQTIRMKLQQQ MACMU11_99_PE2 NOISO QDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQ MICMUGS_1998_PE2 NOISO QEEKLELENRLADLEKMKVEHDVLRQSEKDQYAEKLRASQMAEESARRELQSIXXXXXXX MONDO8_74_PE3 NOISO QDEKLELENKLADLEKIKVEQDVWRQSEKDQYEEKVRASQMAEESAKRELQSIRMKLQQQ MOUSE10_PE1708 NOISO QDEKLELENRLSDLEKMKVERDVWRQSEKEQCEEKLRASQMAEEAARRELQSTRLKLQQQ MYOLUGS_2580_PE2 NOISO QDEKLELENKLADLEKMKVEYDVWRQSEKDQCEEKFRAXXXXXXXXXXXXXXXXLKLQQQ OCHPRGS_3935_PE2 NOISO QNEKLELENRLADLEKMKEERDVR--QEKDQCEEKLRASQAAEEAARRELQSARLKLQQQ ORNANULTRA443_9_PE18 NOISO HDEKIELENKLADLEKTKVEQDVWRQSEKDECEEKLRVSQMAEESARRELQSIRLKLQQQ ORYLA23_2_PE19 NOISO HEEKLEMENRLSALEQQRALQDASEQALREEWEERVHSAQQGEELARRELQNLRMKLQQQ OTOGAGS_2326_PE2 NOISO QEEKLELESRLADLEKMKVEQDVLKQSEKDQCEEKLRASQMAEESARRELQSIRLKLQQQ PANTR12_99_PE3 ENSPTRG00000005302 QDEKLELENRLADLEKMKVEHEVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQ POEGU1A_46_PE9 NOISO QNEKLELENRLADLEKMKLEQDSWRQSEKDQYEEKLRAVQMAEESSKKELQRLRLKIQQQ PONPY12_100_PE2 NOISO QDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQ PROCAGS_3333_PE2 NOISO QDEKLELENRLADLEKMKVEHDVWRQSEKNHCEEKLRASQMAEELARRELQSIRLKLQQQ PTEVAGS_1643_PE2 NOISO QDEKLELENRLTDLEKMKVEYGVWRQSEKDQCEEKLRASQMAEESARRELQSIRLKLQQQ RABIT4_75_PE3 ISOFORMIN QNEKLELENKLADLEKMKAEHDVWRQSEKDQCEEKLRASQMAEELARRELQSIRLKLQQQ RABIT4_75_PE4 ENSOCUG00000016919 QNEKLELENKLADLEKMKAEHDVWRQSEKDQCEEKLRASQMAEELARRELQSIRLKLQQQ RAT7_PE675 NOISO QDEKLELENRLSDLEKMKVEHDVWRQSEKDQCEEKLRASQAAEEAARRELQSIRLKLQQQ SORARGS_3223_PE2 NOISO QDEKLELESRLSDLEKVKVDHDVWRQSEKDQCEEKLRASQMAEEAARRELQNIRLKLQQQ SPETRGS_2549_PE2 NOISO QGEKLELENRLADLEKMKLEHDVWRQSEKDQCEEKLRASQMAEESARRELQSIRLKLQQQ TARSYGS_3736_PE2 NOISO QDEKLELENRLAELENMKVERDVWRQSERDQCEERLRSMQMAEVWARKGRESVRLKLQQQ TETNG19_PE371 NOISO QQEKLDLENRLSSVQQQTSLKAAATKERLAEWEERLSDAKHREVSASQELQDLRTKVQQQ TUPGBGS_2489_PE2 NOISO QDEKLELENRLADLEKMKVERDVWRQSEKDQCEEKLRASQMAEESARRELQSIRLKFQQQ TURTRGS_1422_PE2 NOISO QNEKLELESRLADLEKMKVEHDVRRQSEKDQCEERLRASQMAEESARRELQSIRLKLQQQ XENTR144_2_PE26 NOISO QDERLQLENRIAELERYKVEHDSQKQTEISQIEEKLHIAQTAEESTRRELQSLRSKHQQQ MATCH . CONSENSUS Q?EKLELEN?L??LEK?K?E?D???QSEK???EEKLR??Q??EE????ELQ??R?KLQQQ

AILMEGL192861_1_1_PE2 NOISO IVNIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-ELLNSNQMLKEMVERLKQECRNL ANOCA45_5_PE11 NOISO ASNSEELERERSENADLKQRNHDLQLQVASFSQSEN-DLLDSNQKLKELLERLKIECRNA CALJA9_90_PE1 NOISO ------------------------------------------------------------ CANFA15_38_PE5 NOISO MVNIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-ELLNSNQILKEMVERLKQECRNF CAVPO9_7_PE5 NOISO IVNIENAEKEKNENSDLKQQISSLQIQVTSLTQSEN-ELLNSNQMLKEMVERLKQECRHL CHICK1_PE561 NOISO AIQTEELEEKKRERDDLKQQIQDMQLQVASLSQSEN-DLLEYNQKLKETVERLRQECQNA DANRE4_20_PE23 NOISO GQQLEELETLKAENADLRQQIAELNLQVGTLSHSES-ELLDTNNRLRESLERVREDLRSA DASNOGS_3227_PE2 NOISO FVNMENAEKEKNENSELKQQIGSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF DIPORGS_3028_PE2 NOISO IVNVENAEKQKNENSDLKQQVSHLQIQVTSLTQSEN-DLLNSNEMLKETVERLKQECRSL ECHTEGS_9098_PE3 NOISO FMNIENAEKEKKENSDLREQISSLQIQMTSLAQSES-DLLNSNQLLKEMVERLKEECRNL FUGRU168_PE55 NOISO RSQILEHQSHKVQMGELQQ----------------------------------------- FUGRU3595_PE2 NOISO RSQILEHQSHKVQMGELQQRNNKLEEELRNVSNSQE-QLRETNKQLQGSLERVREELRTT GASACGROUPIV_23_PE9 NOISO SSHVEELERQKAELADLQQQNQELGVQLGTLSHSER-DLMETNQRLKETLDRIREDLRTA GORGO12_98_PE3 ENSGGOG00000026256 IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF GORGO12_98_PE4 ISOFORMIN IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF HORSE28_21_PE2 ENSECAG00000008428 IVDIENAEKEKNENSALKQQISSLQIQVTSLTQSEN-ELLNSNQMLKEMVERLKQECRNL HS12_PE1898 ENSG00000173588 IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF HS12_PE1899 ISOFORMIN IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF HS12_PE1900 ISOFORMIN IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF LAMPAGS_1526_PE2 NOISO IVDIENAEKEKIESSDLKKQISSLQIQVTSLAQSEN-ELLNSNQILKEMVERLKQECRSL LOXAF2_91_PE3 NOISO FVNIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNL MACEUGS_4559_PE2 NOISO MMANEDAEKEKIENADLKHQISGLQIQVTSLTRSET-ELVDSNQKLKDLVERLKQECRNA MACMU11_99_PE2 NOISO IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF MICMUGS_1998_PE2 NOISO XXXXXXXXXXXXXXXXXXXQISRLQIQVTSLTQSEN-DLLNSNQMLKEXXXXXXXXXXXX MONDO8_74_PE3 NOISO MIANENAEKEKVENVDLKQQISGLQIQVTSLTQSET-ELVDSNRMLKEMVEKLKQECRSA MOUSE10_PE1708 NOISO IVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSEN-DLLNSNHMLKDMVERLKQECRNL MYOLUGS_2580_PE2 NOISO IVNIENAEKEKNENSDLKQQISSLQIQVTSLTQSEN-ELLNSNQILKEMVERLKQECRNL OCHPRGS_3935_PE2 NOISO IVDIEKAEKEKNENSDLKQQVSSLQIQLTSLTQSEN-ELLNSNQMLKEMVERLKQECRDL ORNANULTRA443_9_PE18 NOISO SIYTENIEKEKTENSDLKQQINDLQLQVTSLTQSQS-DLLNSNQMLKEMVERLKQECRNA ORYLA23_2_PE19 NOISO SLQLEEQERRRAELSDLQQQTQELLAKVGVLSDAES-DLTEANRRLRESLERTREELRAA OTOGAGS_2326_PE2 NOISO IAIIENAEKEKNENADLKQXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX-XXXXXXXXX PANTR12_99_PE3 ENSPTRG00000005302 IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF POEGU1A_46_PE9 NOISO AMQAEELEEKKCENANLKQQINDIQLQLASLSQSEK-DLLESNQKLKEIIERLKQECQHA PONPY12_100_PE2 NOISO IVTIENVEKEKNENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNF PROCAGS_3333_PE2 NOISO FVDIEKAEKEKNENSDLKQQISSLQIQVTSLTQSEN-DLLNSNQMLKEMVERLKQECRNL PTEVAGS_1643_PE2 NOISO IVNIENAEKEKNENSDLKQQIRSLQIQVTSLSQSEN-ELLNSNQILKEMVERLKQECRNL RABIT4_75_PE3 ISOFORMIN IVDIEKAEKEKNENSDLKQQVSSLQIQVASLARSEN-ELLNSNQMLKEMVERLKQECQNL RABIT4_75_PE4 ENSOCUG00000016919 IVDIEKAEKEKNENSDLKQQVSSLQIQVASLARSEN-ELLNSNQMLKEMVERLKQECQNL RAT7_PE675 NOISO IVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSEN-DLLNSNQMLKDMVERLKQECRHL SORARGS_3223_PE2 NOISO ALNIENAEKEKSENLDLKEQISNLQMQVTSLTQSEN-ELLNSNQLLKETVERLKHECRHL SPETRGS_2549_PE2 NOISO IVNIENAEKEKSENSDLKQQISSLQIQVTSLAQSEN-DLLNSNQMLKEMVERLKQECRNL TARSYGS_3736_PE2 NOISO IVTIENAEKEKHENSDLKQQISSLQIQVASLAQSES-ELLNSNQMLKETVERLKQECRSS TETNG19_PE371 NOISO SSQILELERFKGDLVELQRRNDRLDEQLRKASSSEEEQRKRSNKELQETLERVREELKTT TUPGBGS_2489_PE2 NOISO IVNIENAEKEKNENSDLKQQINNLQIQVTSLAQSEN-DLLNSNQILKQMVERSKQECRNF TURTRGS_1422_PE2 NOISO IVNIENAEKEKNENSDLKQQISSLQIQVTSLAQSEN-ELLNSNQTLKEMVERLKQECRNL XENTR144_2_PE26 NOISO VSYIEQLQKEKRDEEDLKQQINDLKIQVTSLSESEN-SLLLANEKLRQLVEQLKQENRST MATCH CONSENSUS ????E??E??K?E???LKQQ???LQ?QV?SL??SE???LL?SN??LKE??ER???E?R??

AILMEGL192861_1_1_PE2 NOISO RSQAEKAQLEVE-RT-LEEKQIQWLEEKHKLQERITDREEKYNQAKEK----LQRAAIAQ ANOCA45_5_PE11 NOISO RSQAERAQLDSE-KH-LEEKRVEWLEEKHKLIQHTTEMEEYT--RREK----IARAAVLK CALJA9_90_PE1 NOISO ------------------------------------------------------------ CANFA15_38_PE5 NOISO RSQAEKAQLEVE-RT-LEEKQIQWLEEKHKLQERITDREEKYNQAKEK----LQRAAIAQ CAVPO9_7_PE5 NOISO KSQAEKLQLEVE-KT-LEEKQIQWLEEKHKLQERITDREEKYNQAKEK----LQRAATAQ CHICK1_PE561 NOISO RTQAEKAQLETE-KT-LEYKRIEWLEEKHMLTQRITEKEEKYNEVKNK----LCRAAVAQ DANRE4_20_PE23 NOISO RTQMERTQQEAE-RL-VEERRVEWLEEKHKLQDIEAELREKYSQAKER----LQRAAFAQ DASNOGS_3227_PE2 NOISO KSQAEKTQLEVE-KT-LEEKQVQWLEEKHKLHERITDREEKYNQAKEK----LQRAAVAQ DIPORGS_3028_PE2 NOISO RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERIKDREEKYNQAKEK----LQRAATAQ ECHTEGS_9098_PE3 NOISO RSQAEKAQLEVE-KX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX FUGRU168_PE55 NOISO ------------------------------------------------------------ FUGRU3595_PE2 NOISO QVQAERSQQEAERSQLLQHSQNQSLEEKRKLQ-------QKYAEAKEK----MQRAAAAQ GASACGROUPIV_23_PE9 NOISO RTQAERSQHEAE-RL-VEDHRVEWLEEKHKLL-------EKYSQVKER----LQRAAVAQ GORGO12_98_PE3 ENSGGOG00000026256 RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ GORGO12_98_PE4 ISOFORMIN RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ HORSE28_21_PE2 ENSECAG00000008428 RSQAEKAQLEVE-KT-LEEKQILWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ HS12_PE1898 ENSG00000173588 RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ HS12_PE1899 ISOFORMIN RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ HS12_PE1900 ISOFORMIN RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ LAMPAGS_1526_PE2 NOISO RSQAEKAQLEVE-KT-LEERQIQWMEEKHKLHERITDREERYNQAKEK----LQRAAIAQ LOXAF2_91_PE3 NOISO RSQAEKARLEVE-KT-LEEKQLQWLEEKHKLHERITDREEKYNQAREK----LQRAAVAQ MACEUGS_4559_PE2 NOISO RAQAEKTQLEAE-NS-LEEKRVEWLEEKRMLHDRLKEKEEKYSQAKEK----LQRAARAQ MACMU11_99_PE2 NOISO RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERITEREEKCNQAKEK----LQRAAIAQ MICMUGS_1998_PE2 NOISO XXXX-XXXXXXXXXT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAATAQ MONDO8_74_PE3 NOISO RTQADKAQLEAE-NA-LEEKRIEWLEEKHKLHERIQEKEEKYKQAKEK----LQRASLAQ MOUSE10_PE1708 NOISO RSQAEKAQLDVE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAATAQ MYOLUGS_2580_PE2 NOISO RSQAEKAQLEVE-KT-LEEKQIQWLEEKQKLHERITDREEKYNQAKEK----LQRAAIAQ OCHPRGS_3935_PE2 NOISO RSQTEKTQLAAE-KT-LEEKHMQWLEEKHRLQEHITDREEQYKQAKEK----LQRAALAQ ORNANULTRA443_9_PE18 NOISO RSQAEKAQLDAE-KI-LEEKQIVWLEEKHKFHERVTEREEKYKHIKDK----LQRAAIAQ ORYLA23_2_PE19 NOISO RVQAERNQHDAE-RA-EEDRRVEWLEEKHKLQEREAGLQQKYSQLKEK----LQRAAVAQ OTOGAGS_2326_PE2 NOISO XXXXXXXXXXXXXXT-LEERQIQWLEEKHKLHERIAEREEKYNQAKEK----LQRAAIAQ PANTR12_99_PE3 ENSPTRG00000005302 RSQAEKVQLEAE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ POEGU1A_46_PE9 NOISO RAQAEKAQLETE-KT-SEYQRMEWLQEKHMLTQRITEFEEKYKQMKNK----LSRAAVAQ PONPY12_100_PE2 NOISO RSQAEKAQLEAE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ PROCAGS_3333_PE2 NOISO RSQAEKAQLEAE-KT-LEEKQVQWLEEKHKLHERITDREEKCNQAKEK----LQRAAIAQ PTEVAGS_1643_PE2 NOISO RSQAEKAQLEVE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAAIAQ RABIT4_75_PE3 ISOFORMIN RDQAENAQRTV-KKT-MDEKNTEWLKEKRKLQEHITEREEKYNQAKEK----LQRAAIAQ RABIT4_75_PE4 ENSOCUG00000016919 RDQAENAQRTDEKGT-MDEKNTEWLKEKRKLQEHITEREEKYNQAKEK----LQRAAIAQ RAT7_PE675 NOISO RSQAEKVQLEVE-KT-LEEKQIQWLEEKHKLHERITDREEKYNQAKEK----LQRAATAQ SORARGS_3223_PE2 NOISO RSQAEKAQMEVE-KT-VKEKQIQWLEEKHKLHERITDREEKYSQAKAN----LQRAAMAQ SPETRGS_2549_PE2 NOISO RSQAEKVQVEVE-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TARSYGS_3736_PE2 NOISO RSQAEQAQLGVE-KT-LEEKQIQWLAEKHQLHERLEDREEKYHQVKEK----LQRAAIAQ TETNG19_PE371 NOISO QVQAERVQQEAERK--LQDCQTEWTEERRNLR-------QKYSEAKEK----MQRAAAAQ TUPGBGS_2489_PE2 NOISO RSLSEKAELEVE-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TURTRGS_1422_PE2 NOISO RSQAEKAQLEVE-KA-LEEKQIQWLEEKHRLHERITDREEKYNQAKEK----LQRAAIAQ XENTR144_2_PE26 NOISO RNQVEKTQHNAE-KE-LESNRIEWLQEKHKLQETLSELQDKYSQAKEK----LQRAAAAQ MATCH CONSENSUS R?QAE??Q???E???????????WL?EK??L????????EKY???KEK????LQRAA?AQ

AILMEGL192861_1_1_PE2 NOISO KK--RKSLHENKLK--RLQEKVEVLEAKREELETENQVLNRQNVPFEEYTRLQKRLKDIQ ANOCA45_5_PE11 NOISO KG--IKTLNDNKQK--KLMKKIELLEAKREELETENQVLNRQNVPFEEHIRLQKRLKDLQ CALJA9_90_PE1 NOISO ------------------------------------------------------------ CANFA15_38_PE5 NOISO KK--RKSLHENKLK--RLQEKVEILEAKREELETENQVLNRQNVPFEEYTRLQKRLRDIQ CAVPO9_7_PE5 NOISO KK--RKSLHENKLK--RLQEKVDVLEAKREELEAENQVLTRQNVPFEEYTRLQKRLKDIQ CHICK1_PE561 NOISO KK--RKTLNDNKQR--RMQEKLQLLEAKIEELEKENQVLNRQNVSYEEYARLQKRLKDLQ DANRE4_20_PE23 NOISO KK--RKTMTELKEN--KLKDKIQLLEAKIAELEIEASAEKKKSSYSXEHAQLSKRLRELQ DASNOGS_3227_PE2 NOISO KK--RKSLHENKLR--RLQEKVEVLEAKREELETEN----QQNVPFEEYTRLQKRLKDLQ DIPORGS_3028_PE2 NOISO KKXXXXXXXXXXXX--XXXX--XXXXXXXXXXXXXXXXXXXQNVPFEEYTRLQKRLKDIQ ECHTEGS_9098_PE3 NOISO RKSLHE----NKLK--RLQEKVELLEAKREELETENQVLNRQNVPFEEYTRIQKRLKDIQ FUGRU168_PE55 NOISO ------------------------------------------------------------ FUGRU3595_PE2 NOISO KK--VE------------------------------------------------------ GASACGROUPIV_23_PE9 NOISO KK--RKTLTENREK--KMQYKIQLREARIEELELEAA-SKRRPLLSEEQAPVNRRLKELQ GORGO12_98_PE3 ENSGGOG00000026256 KK--RRSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQ GORGO12_98_PE4 ISOFORMIN KK--RRSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQ HORSE28_21_PE2 ENSECAG00000008428 KK--RKSLHENKLK--RLQEKVEILEAKREELETENQVLNRQSVPFEDYTRLQKRLKDIQ HS12_PE1898 ENSG00000173588 KK--RKSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQ HS12_PE1899 ISOFORMIN KK--RKSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQ HS12_PE1900 ISOFORMIN KKLEQDLELGCPSVTDTYRESVFPPPPLKRD------LLK-------------------- LAMPAGS_1526_PE2 NOISO KK--RKSLHENKLK--RLQEKVEVLEAKREELETENQVLNRQNVPFEEYTRLQKRLKDIQ LOXAF2_91_PE3 NOISO KK--RKSLHENKLK--RLQEKIEVLEAKREELETENQVLNRQNVPFEEYTRIQKRLKDIQ MACEUGS_4559_PE2 NOISO KK--RKSLYENKLK--KLQKKVELLEAKKEELETENQVLNRQNVPYEDYTKLQKRLKDIQ MACMU11_99_PE2 NOISO KKAIRKSLHENKLK--RLQEKVEVLEAKKEELETENQV---------------------- MICMUGS_1998_PE2 NOISO KKAXRKSLHENKLK--RLQEKVEVLEAKKEELETENQALNRQNVPFEEYTRLQKRLKDIQ MONDO8_74_PE3 NOISO KK--RKSLFENKLK--KLQEKVELLEAKNEELETEKQVLNRQNVPHEDYTKLQKRLKDIQ MOUSE10_PE1708 NOISO KK--RKSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQ MYOLUGS_2580_PE2 NOISO KK-ARKSLHENKLK--RLHEKVEVLEAKREELETENQVLNRQNVPFEEYTRLQKRLKDIQ OCHPRGS_3935_PE2 NOISO KK--RKALYENKLK--RLQEKVEILEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQ ORNANULTRA443_9_PE18 NOISO KK--RKSLHENKLK--RLQDKVELLEAKKEELETENQVLNRQNVPYEDYTRLQKRLKDIQ ORYLA23_2_PE19 NOISO KK--RKHQTENREK--RLRDRIQLLEAKLEELELEAAAAKKRPALSEEHAQLHRRLRELQ OTOGAGS_2326_PE2 NOISO KKAXXXXXXXXXX--XXXXXXXEVLEAKKEELETENQVLNXXXXXXXXXXXXXXXXXXXX PANTR12_99_PE3 ENSPTRG00000005302 KK--RKSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQ POEGU1A_46_PE9 NOISO KK--ASTLNDNKQR--RMHEKIELLEAKMEELEKENQVLNRQNVSSEEYARLQKRLKDLQ PONPY12_100_PE2 NOISO KK--RKSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQ PROCAGS_3333_PE2 NOISO KKXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXQNVPFEEYTRIQKRLKDIQ PTEVAGS_1643_PE2 NOISO KK--RKSLHENKLK--RLQEKVEVLEAKREELETENQVLNRQHVPFEDYTRLQKRLKDIQ RABIT4_75_PE3 ISOFORMIN KK--RKSLHENKLK--RMQDKVEVLEAKKEELETENQVLKRQNVPFEEYTRLQKRLKDIQ RABIT4_75_PE4 ENSOCUG00000016919 KK--RKSLHENKLK--RMQDKVEVLEAKKEELETENQVLKRQNVPFEEYTRLQKRLKDIQ RAT7_PE675 NOISO KK--RKSLHENKLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQ SORARGS_3223_PE2 NOISO NKAXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXQNVPFEEYTRLQKRLKDIQ SPETRGS_2549_PE2 NOISO RKSLHEN----KLR--RLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQ TARSYGS_3736_PE2 NOISO KK--RKSL--NKLK--RLQDKVEILEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQ TETNG19_PE371 NOISO KK--RKTLTETKER--KLQNKIQLLEAQLETLELEVSAAKR-NLSFCEQA-HKRKIKDLL TUPGBGS_2489_PE2 NOISO RKSLYEN----KLK--RLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQ TURTRGS_1422_PE2 NOISO KK--RKSLHENKLK--RMQEKVEVLEAKREELETENQVLNRQNVPFEEHTRLQKRLKDIQ XENTR144_2_PE26 NOISO KK--RKTLNENKCI--KLQKKIELLEATKEELEAQKHVLNRQNVPHEEFGRLQKRLKDLQ MATCH CONSENSUS KK??????????????????K???LEA??EELE?E???????????E??????KRLKD?Q

AILMEGL192861_1_1_PE2 NOISO RRHNEFRSLILVPNIPPTASINPVSFQS-SAMVPGTDLSFPPHMQEEQHQRELSLLRKRL ANOCA45_5_PE11 NOISO RRHNEFRRIILFPNIPI---LNPVSLLS-STLIPGPEASFP-LLQEEQHQKEVSLLRKRL CALJA9_90_PE1 NOISO ------------------------------------------------------------ CANFA15_38_PE5 NOISO RRHNEFRSLILVPNIPPAASINPVSFQS-SGTFPGMDLSFPAHMQEEQHQRELSLLRKRL CAVPO9_7_PE5 NOISO RRHNEFRSLILVPNIPPPASINPVSFQA-SAMAPGVELCFPPLVQEEQHQRELSLLRKRL CHICK1_PE561 NOISO RRHNEFRSLILNPGIPS---LNPISATS-APVPPPGPDVPFLFLQEEQHQRELSVLRKRL DANRE4_20_PE23 NOISO RRHNEFRRLLLGNQMTSSTP-------L-AQSLLIPNESIFSNIQEEQHQRELCVLRRRL DASNOGS_3227_PE2 NOISO RRHNEFRSLILVPNMPPKASINPVSFQS-STVVPGIELAFPPHLQXXXXXXXXXXXXXRL DIPORGS_3028_PE2 NOISO RRHNEFRSLILVPHMPPTAPTNPVNLQS-SAMVPGMDLAFPPHVQEEQHQRELSLLRKRL ECHTEGS_9098_PE3 NOISO RRHNEFRSLILIPNVPPTTPLNPVSFQS-SDMGPGVELSFPPHLQ--------------- FUGRU168_PE55 NOISO ------------------------------------------------------------ FUGRU3595_PE2 NOISO ------------------------------------------------------------ GASACGROUPIV_23_PE9 NOISO RRHNEFRRLLLGGQGPYSAGPAFLTSSP-APFVFLGSERPLGTIPEEQQQRELSLLRRRL GORGO12_98_PE3 ENSGGOG00000026256 RRHNEFRSLILVPNMPPTASINPVSFQS-SAMVPSMELPFPPHMQEEQHQRELSLLRKRL GORGO12_98_PE4 ISOFORMIN RRHNEFRSLILVPNMPPTASINPVSFQS-SAMVPSMELPFPPHMQEEQHQRELSLLRKRL HORSE28_21_PE2 ENSECAG00000008428 RRHNEFRSLILVPNIPPTASINPVSFQS-STMVPGMELSFPPHMQEEQHQRELSLLRKRL HS12_PE1898 ENSG00000173588 RRHNEFRSLILVPNMPPTASINPVSFQS-SAMVPSMELPFPPHMQEEQHQRELSLLRKRL HS12_PE1899 ISOFORMIN RRHNEFRSLILVPNMPPTASINPVSFQS-SAMVPSMELPFPPHMQEEQHQRELSLLRKRL HS12_PE1900 ISOFORMIN ------------------------------------------------------------ LAMPAGS_1526_PE2 NOISO RRHNEFRSLILVPNLPPTASINPVSFQS-STVIPGMELSFSPHMQEEQHQRELSLLRKRL LOXAF2_91_PE3 NOISO RRHNEFRSLILVPNMPPTASINPVSFQS-SNMGPGMELSFPPHLQEEQHQRELSLLRKRL MACEUGS_4559_PE2 NOISO RRHNEFRTLILVPNVPPATSFNSVSLLS-APLPSGVETSFPPHLPEEEHQRELSLLRKRL MACMU11_99_PE2 NOISO ------------------------------------------------------------ MICMUGS_1998_PE2 NOISO RRHNEFRSLILVPNMPPTASINPASFQS-SAMVLGMETCFP-HMQEEQHQRELSLLRKRL MONDO8_74_PE3 NOISO RRHDEFRTLILVPNMPPTKSFNPVSFLS-GPLPPDVEPSFPTHLPEEEHQRELSLLRKRL MOUSE10_PE1708 NOISO RRHNEFRSLILVPNMPPTASISPANFQS-AVTVPGAELSFPPHLQEEQHQRELSLLRKRL MYOLUGS_2580_PE2 NOISO RRHNEFRSLILVPNIPPTASINPVSLQS-SNIIPGMELAFPPHMQEEQHQRELSLLRKRL OCHPRGS_3935_PE2 NOISO RRHNEFRSLILVPNVPAAASINPLNFQP-SAVVPGTDLSFPPQIQEEQHQRELSLLRRRL ORNANULTRA443_9_PE18 NOISO RRHNEFRTLILVPDMPSATSHNPISFLSSSSLVPGVEAAFPPHLQEEQHQKELSLLRKRL ORYLA23_2_PE19 NOISO RRHNEFRRLLLGSQGVFGGGPALLTSSA-AAAPLLLSERLPSN---DPQDADFSVLRRRL OTOGAGS_2326_PE2 NOISO XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEEQHQRELSLLRKRL PANTR12_99_PE3 ENSPTRG00000005302 RRHNEFRSLILVPNMPPTASINPVSFQS-SAMVPSMELPFPPHMQEEQHQRELSLLRKRL POEGU1A_46_PE9 NOISO RRHNEFRSIILNPNIPS---LNPVGISA-NVFLPDAPLFFPLNFKEEQHQRELALLGKRL PONPY12_100_PE2 NOISO RRHNEFRSLILVPNMPPTASINPVSFQS-SAMVPSMELPFPPHMQEEQHQRELSLLRKRL PROCAGS_3333_PE2 NOISO RRHNEFRSLILLPNMPLTASINPLSFQS-SNMGPGMELSFPPHLQ--------------- PTEVAGS_1643_PE2 NOISO RRHNEFRSLILVPNIPPTSSINPVSFQS-STMVPGMELAFPPHMQEEQHQRELSLLRKRL RABIT4_75_PE3 ISOFORMIN RRHNEFRSLILVPSMPPTASINPVSFQS-SAMVPAMELSFPPHMQEEQHQRELSLLRKRL RABIT4_75_PE4 ENSOCUG00000016919 RRHNEFRSLILVPSMPPTASINPVSFQS-SAMVPAMELSFPPHMQEEQHQRELSLLRKRL RAT7_PE675 NOISO RRHNEFRSLILVPNMPPAASVNPANFQS-SAIVPGVELSFPPHLQEEQHQRELSLLRKRL SORARGS_3223_PE2 NOISO RRHNEFRSLILIPNIPPTASINPVSFPS-SSMVPGMELSFPPHMQEEQHQRELSVLRKRL SPETRGS_2549_PE2 NOISO RRHNEFRSLILVPNMPPTASVNPVSIQS-SAVVPGMELSFPPHMQEEQHQRELSLLRKRL TARSYGS_3736_PE2 NOISO RRHNEFRSLILAPNIPTAAPLPPSGFPL-SAMLPGLELAFPPHMQEEQHQRELSLLRKRL TETNG19_PE371 NOISO RRHREFQSVLFEGGFKDVPRITTSSI---RPFDPR-AEELPPNTPAEQHQEIDELWRRT- TUPGBGS_2489_PE2 NOISO RRHNEFRSLILVPNVPPTASLNPVSFPS-SAMVPGIELSFPPHMQ--------------- TURTRGS_1422_PE2 NOISO RRHNEFRSLILGPNIPSTASINPGSFQS-PTVIPGMELSFPPHMQEEQHQRELSLLRKRL XENTR144_2_PE26 NOISO RRHNEFRSLILGPNISASGLLNPVSFLS-STVVPGADLSFI-NAQEEQHQRELSLLRKRL MATCH CONSENSUS RRHNEFR?L?L???????????????????????????????????????????????RL

AILMEGL192861_1_1_PE2 NOISO EELETTQRKQLEELGSPGE--------------------------- ANOCA45_5_PE11 NOISO EELETSQRKQLRELAPSTE--------------------------- CALJA9_90_PE1 NOISO ---------------------------------------------- CANFA15_38_PE5 NOISO EELETTQRKQLEELGSTGE--------------------------- CAVPO9_7_PE5 NOISO EELETTQRRQLEELGSPGE--------------------------- CHICK1_PE561 NOISO EDLETTQRKQLQELGPAGERLPARARRELTSSRGAEGAAVQSEDST DANRE4_20_PE23 NOISO EELENSQQQQLEELAAPLDRDR------------------------ DASNOGS_3227_PE2 NOISO EELETTQRRQLEELGSPGE--------------------------- DIPORGS_3028_PE2 NOISO EELETTQRKQLEELGSSGE--------------------------- ECHTEGS_9098_PE3 NOISO ---------------------------------------------- FUGRU168_PE55 NOISO ---------------------------------------------- FUGRU3595_PE2 NOISO ---------------------------------------------- GASACGROUPIV_23_PE9 NOISO EDLESAQQLQLEELGSLVHGE------------------------- GORGO12_98_PE3 ENSGGOG00000026256 EELETTQRKQLEELGSSGE--------------------------- GORGO12_98_PE4 ISOFORMIN EELETTQRKQLEELGSSGE--------------------------- HORSE28_21_PE2 ENSECAG00000008428 EELETTQRKQLEELGSPGE--------------------------- HS12_PE1898 ENSG00000173588 EELETTQRKQLEELGSSGE--------------------------- HS12_PE1899 ISOFORMIN EELETTQRKQLEELGSSGE--------------------------- HS12_PE1900 ISOFORMIN ---------------------------------------------- LAMPAGS_1526_PE2 NOISO EELETTQRKQLEELGSPGE--------------------------- LOXAF2_91_PE3 NOISO EELETTQRKQLEELGSPGE--------------------------- MACEUGS_4559_PE2 NOISO EELETTQRKQLEELGPPGE--------------------------- MACMU11_99_PE2 NOISO ---------------------------------------------- MICMUGS_1998_PE2 NOISO EELETTQRKQLEELGPPGE--------------------------- MONDO8_74_PE3 NOISO EELETTQRKQLEELGPPGE--------------------------- MOUSE10_PE1708 NOISO EELETTQRKQLEELGSPGE--------------------------- MYOLUGS_2580_PE2 NOISO EELETTQRKQLEELGSPGE--------------------------- OCHPRGS_3935_PE2 NOISO EELETTQRKQLEELGSLGE--------------------------- ORNANULTRA443_9_PE18 NOISO EDLETTQRKQLQELGPPGE--------------------------- ORYLA23_2_PE19 NOISO ESLESAQQQQLEELG------------------------------- OTOGAGS_2326_PE2 NOISO EELETTQRKQLEEFGSPGD--------------------------- PANTR12_99_PE3 ENSPTRG00000005302 EELETTQRKQLEELGSSGE--------------------------- POEGU1A_46_PE9 NOISO EELETRQRKQLEDLGPSRE--------------------------- PONPY12_100_PE2 NOISO EELETTQRKQLEELGSSGE--------------------------- PROCAGS_3333_PE2 NOISO ---------------------------------------------- PTEVAGS_1643_PE2 NOISO EELETTQRKQLEELGSPGE--------------------------- RABIT4_75_PE3 ISOFORMIN EELETTQRKQLEELGSLGE--------------------------- RABIT4_75_PE4 ENSOCUG00000016919 EELETTQRKQLEELGSLGE--------------------------- RAT7_PE675 NOISO EELETTQRKQLEELGSPGE--------------------------- SORARGS_3223_PE2 NOISO EELETTQRKQLEELGSPGE--------------------------- SPETRGS_2549_PE2 NOISO EELETTQRKQLEELGSPGE--------------------------- TARSYGS_3736_PE2 NOISO EELETTQRKQLEELGSPGE--------------------------- TETNG19_PE371 NOISO -----DHPEQLEELATVPA--------------------------- TUPGBGS_2489_PE2 NOISO ---------------------------------------------- TURTRGS_1422_PE2 NOISO EELETTQRKQLEELGFPGE--------------------------- XENTR144_2_PE26 NOISO EDLETTQRKQLEELGPP----------------------------- MATCH CONSENSUS E?LE??Q??QL?EL????????????????????????????????


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