Alignment of the gene Family HOG000111441 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL193899_1_PE4 NOISO DTPLRRSRRLEGLNPESPETPS--SVLS--ARRALVEVKSDSEETREAGSP-S------- BOVIN29_40_PE9 NOISO DTPLRRSRRLEGLKPESPENPT--SVLR--VRRALVEFESNPKETGEPRSP--------- CALJA11_121_PE13 ENSCJAG00000016483 DTPLRRSRRLEGLRPECSESLT--LVSR--ARRALVEFASNPEETRESGSPPS------- CALJA2_61_PE1 NOISO -VHL--RRGLETLCLVRGSHGRRASVPQ--RRLALVEFKTIPEETRKPRSPPN------- CALJA2_62_PE30 NOISO ----------------PKSHGRRASVPQ--RRLALVEFETIPEETRKPRSPPN------- CANFA18_60_PE1 NOISO --------------------------AP--PRRPHVSWGSG------------------- CAVPO65_10_PE4 NOISO DTPLRRSRRLEGLTPEAAESFA--SAGQ--SRQAFVEIAAGPEEAQEPGQGSLPRP---- DASNOGS_1756_PE1 NOISO ------------------------------------------------------------ DIPORGS_5019_PE2 NOISO DAPLRRSRRLGGLNPESAATVA--SASR--ARRALVQSETNEEGK--------------- ERIEUGS_2141_PE1 NOISO DTPLRRSRRLSGLKPESPDSSA--PVLR--ARRALVEFEPTPEEAQGLGSPRS------- FELCAGS_3606_1_PE4 NOISO DTPLRRSRRLEGLNPESPDTPS--SVLQ--ARRALVEFRSDPEETREPGSPRS------- GORGO11_60_PE14 NOISO DTPLRRSRRLGGLRPESPESLT--SVSR--TRRALVEFESNPEETREPGSPPS------- HORSE12_21_PE14 NOISO DTPLRRSRRLEGLRPESPERSA--SVLR--AKRALVEFDPNPEETREPGSPRS------- HS11_PE1518 ENSG00000110104 DTPLRRSRRLGGLRPESPESLT--SVSR--TRRALVEFESNPEETREPGSPPS------- LOXAF71_10_PE3 ENSLAFG00000009449 DTPLRRSRRLGGLKPESPASPS--SVLQ--ARRALVEFESNPEETKEPGSPRSP------ LOXAF71_10_PE4 ISOFORMIN DTPLRRSRRLGGLKPESPASPS--SVLQ--ARRALVEFESNPEETKEPGSPRSP------ MACMU14_14_PE27 NOISO DTPLRRSRRLGGLRPESPESLT--SVSR--VRRALVELQSNPEETREPGSPPS------- MICMUGS_3331_PE3 NOISO DTPLRRSRRLEGLEPESPESPT--TVSR--ARRALVEFESNPEETREPGSPRSV------ MONDO5_307_PE8 ISOFORMIN ------------------------------------------------------------ MONDO5_307_PE9 ENSMODG00000020334 ETPRRRSRRLEGLEAESPATPATPSRGPRKARRALLGSK--AEAALEPSQSLDV----GT MOUSE19_PE549 NOISO DTPLRRSRRLEGLKPLSPENLPVPEVSR--AKRALVDFKSNSEETGELKSTRVPPLSLPS OCHPRGS_4480_PE6 NOISO DTPLRRSRRLGGLKPESTEKRT--SVSQ--VRRALVEVETNGEDTRPPGSLED------- OTOGAGS_3910_PE4 NOISO DTPLRRSRRLEGLEPESRESLT--PVSR--VKRALVEFESNPEETREPGSSQS------- PANTR11_62_PE6 ENSPTRG00000003721 DTPLRRSRRLGGLRPESPESLT--SVSR--TRRALVEFESNPEETREPGSPPS------- PIG2_10_PE18 NOISO DTPLRRSRRLEGLKPESPENPT--PVLQ--ARRALVELESHPEEAREPGSPRN------- PONPY11_16_PE22 NOISO DTPLRRSRRLGGLRPECPESLT--SVSR--TRRALVELESNPEETREPGSPPS------- PROCAGS_6033_PE2 NOISO DTPVRRSRRLEGLKPESPENPT--SVLR--ARRALVEIKSNPEEPKEPGSPQSP------ PTEVAGS_901_PE1 NOISO DTPLRRSRRLEGLNPESSESST--SLLQ--AKRALLEFESNPEETKEPGS-RS------- RABIT1_198_PE11 NOISO DTPLRRSRRLGGLNPESTGRLT--SLSQ--VRRALVEVESIGGETREPESLQG------- RAT1_PE3545 NOISO GTPLRRSRRLEGLNPLSLENLPDPEVSR--AKRALVDFKSNPEETRELESPRVPPLDLVS TUPGBGS_4118_PE3 NOISO DTPLRRSRRLGGLEPESSENYT--AVSR--VRRALVALDSNPEQTREPGSPRRV------ TURTRGS_774_PE1 NOISO DTPLRRSRRLEGLKPESPENPT--SVLR--ARRALVEFESNPEERREPGSPRS------- MATCH CONSENSUS ?TPLRRSRRL?GL?P?????????????????RALV??????E??????S??????????

AILMEGL193899_1_PE4 NOISO ------------------------------------------------------------ BOVIN29_40_PE9 NOISO ------------------------------------------------------------ CALJA11_121_PE13 ENSCJAG00000016483 ------------------------------------------------------------ CALJA2_61_PE1 NOISO ------------------------------------------------------------ CALJA2_62_PE30 NOISO ------------------------------------------------------------ CANFA18_60_PE1 NOISO ------------------------------------------P--------SGRAMDARP CAVPO65_10_PE4 NOISO ------------------------------------------------------------ DASNOGS_1756_PE1 NOISO ------------------------------------------------------------ DIPORGS_5019_PE2 NOISO ------------------------------------------------------------ ERIEUGS_2141_PE1 NOISO ------------------------------------------------------------ FELCAGS_3606_1_PE4 NOISO ------------------------------------------------------------ GORGO11_60_PE14 NOISO ------------------------------------------------------------ HORSE12_21_PE14 NOISO ------------------------------------------------------------ HS11_PE1518 ENSG00000110104 ------------------------------------------------------------ LOXAF71_10_PE3 ENSLAFG00000009449 ------------------------------------------------------------ LOXAF71_10_PE4 ISOFORMIN ------------------------------------------------------------ MACMU14_14_PE27 NOISO ------------------------------------------------------------ MICMUGS_3331_PE3 NOISO ------------------------------------------------------------ MONDO5_307_PE8 ISOFORMIN PKKR-------------------------------------------------------- MONDO5_307_PE9 ENSMODG00000020334 PKKR-------------------------------------------------------- MOUSE19_PE549 NOISO PGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPS OCHPRGS_4480_PE6 NOISO ------------------------------------------------------------ OTOGAGS_3910_PE4 NOISO ------------------------------------------------------------ PANTR11_62_PE6 ENSPTRG00000003721 ------------------------------------------------------------ PIG2_10_PE18 NOISO ------------------------------------------------------------ PONPY11_16_PE22 NOISO ------------------------------------------------------------ PROCAGS_6033_PE2 NOISO ------------------------------------------------------------ PTEVAGS_901_PE1 NOISO ------------------------------------------------------------ RABIT1_198_PE11 NOISO ------------------------------------------------------------ RAT1_PE3545 NOISO PQPQPETSPESPC----------------------------------------------- TUPGBGS_4118_PE3 NOISO ------------------------------------------------------------ TURTRGS_774_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193899_1_PE4 NOISO -------------ARQPGLESPRRQPEPTPGSP---------ILRQGAGLGSPVREPEPD BOVIN29_40_PE9 NOISO ----------------PGLGSPSRQPETSPGSP---------SLPNGPALGSPRKQPELD CALJA11_121_PE13 ENSCJAG00000016483 -------------VQQAGLGSPERPPETSPGSP---------SLQRGAGLESPQGHPEPG CALJA2_61_PE1 NOISO ------------------GAPPQRHPETSPGSP---------SLQQGAGLGSPQRQPEPS CALJA2_62_PE30 NOISO ------------------GAPPQRHPETSPGSP---------SLQQGAGLGSPQRQPEPS CANFA18_60_PE1 NOISO EGPDAESGSDPRDAREPGRPGSVRQPEPGPGAP---------ALRRDAGRRPPPMAPG-- CAVPO65_10_PE4 NOISO -------------------------SESSAGPLT--------REQRGADAGSPRG----- DASNOGS_1756_PE1 NOISO ------------------------------------------------------------ DIPORGS_5019_PE2 NOISO -------------EQPHGLESAPRPPETSPGSP---------SPRQDADLGSPRGHSEPN ERIEUGS_2141_PE1 NOISO -------------EPRPGPESPRSQPETSPGSP---------SQPQGAGLGCPRRQLEPG FELCAGS_3606_1_PE4 NOISO -------------ARQPGLESPRRQPETSPGSP---------ILPQGAGLGSPRREPEPG GORGO11_60_PE14 NOISO -------------VQRAGLGSPERPPKTSPGSP---------RLQQDAGLEFPQGQPEPG HORSE12_21_PE14 NOISO -------------ALPPGLESPRGQPETSPGSP---------GLRQGTDLGSPRKEPELG HS11_PE1518 ENSG00000110104 -------------VQRAGLGSPERPPKTSPGSP---------RLQQGAGLESPQGQPEPG LOXAF71_10_PE3 ENSLAFG00000009449 -------------PRQPGLGSPQRQQETSPGSL---------SLRQDVELGSPQRLPEPG LOXAF71_10_PE4 ISOFORMIN -------------PRQPGLGSPQRQQETSPGSL---------SLRQDVELGSPQRLPEPG MACMU14_14_PE27 NOISO -------------VQQAGLGSPERPPETSPGSP---------RLQQGAGLESPQVQPEPG MICMUGS_3331_PE3 NOISO --------------QQAGLRSPQRQPETCPGSP---------SRQQSAALGSPQREPEPG MONDO5_307_PE8 ISOFORMIN ---ADDLGSPQ--RQARGPKSPQNQSGPFLGSPKNKNKDLGSARRKDQLPGSPRNHPQPG MONDO5_307_PE9 ENSMODG00000020334 ---ADDLGSPQ--RQARGPKSPQNQSGPFLGSPKNKNKDLGSARRKDQLPGSPRNHPQPG MOUSE19_PE549 NOISO PGPQPET-SPGSPCPPLSLPSPGPQPEASPGSP---------GPRQDADDGSPQRQPEPH OCHPRGS_4480_PE6 NOISO -------------VWQLGPSSPGHQQETNTESP---------SLREKAGLGSPQGQPDPD OTOGAGS_3910_PE4 NOISO -------------VLQAGPESLQSLPETRPRSG---------SLQQGTDLGSPEREPEPG PANTR11_62_PE6 ENSPTRG00000003721 -------------VQRAGLGSPERPPKTSPGSP---------RLQQDAGLESPQGQPEPG PIG2_10_PE18 NOISO -------------VQPPGLGSPRRQSETAPVSP---------SLQEGAGLGSSQRQPEPG PONPY11_16_PE22 NOISO -------------VQRAGLGSPERPPKTSPGSP---------RLQQGSGLESPQGQPEPG PROCAGS_6033_PE2 NOISO -------------SRQPGVESSRRQPETSPVSL---------SPRQDAGQGSPRRQPEPG PTEVAGS_901_PE1 NOISO -------------VRQPGLGSPGRQPETCPGSP---------SLRQGAGLESPRKEPDPG RABIT1_198_PE11 NOISO -------------VLQPGPSSPRLRQETSPGSP---------SPRQDEGLGR----PEPG RAT1_PE3545 NOISO -------------------------------------------PKQDAGFGSPQRQPEPH TUPGBGS_4118_PE3 NOISO -----------------------QLREPSPGSP---------VLRQETDLKFPPREPEPG TURTRGS_774_PE1 NOISO -------------VRPPGLESPRHQPETSPESP---------SLREGAGLGSPREQPEPG MATCH CONSENSUS ?????????????????????????????P?S???????????????????SP???P?P?

AILMEGL193899_1_PE4 NOISO LGSLERQQDPGLESPQTLPESGPESPGFQPKPSGESAEFSQAQEEL-------------- BOVIN29_40_PE9 NOISO SGSPEGHRDPGLNFPQNQPESSPESHLLQPKPSEESPKFSQNQGEA-------------- CALJA11_121_PE13 ENSCJAG00000016483 PSSPQRQQDLHPESPQRQPESSPESPRCQPKPSEEAPKCSQGQGVL-------------- CALJA2_61_PE1 NOISO PGSPQHYQ----QSPQRQPESSPESPQYQPKPSEEAPKCSQCHGELASEWAQSP------ CALJA2_62_PE30 NOISO PGSPQH------QSPQRQPESSPESPQYQPKPSEEAPKCSQCHGELASEWAQSP------ CANFA18_60_PE1 NOISO ------PADPGPELPQTPPEAAPEPPGLQPGPRGESAGFPQARRELDS------------ CAVPO65_10_PE4 NOISO ------QRGPGPETPPRRPEARPEAPQHVDLPG--------------------------- DASNOGS_1756_PE1 NOISO ------------GSPQKQPESGLESPRRQPKPSGELPEFSQAQREP-------------- DIPORGS_5019_PE2 NOISO QGSPQQDGV--PESSPSQPEPRPEPPRCE-----ESPRASQ------------------- ERIEUGS_2141_PE1 NOISO PPSPQRQQDAGEVSPRGQREPSPESPRLQPEPSEASPKAPQDLENPTPDLARR------- FELCAGS_3606_1_PE4 NOISO PGSLQRQQDPGPESPPILPESGPESPGFHPKLSGESAESSQAQEEL-------------- GORGO11_60_PE14 NOISO AASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVL-------------- HORSE12_21_PE14 NOISO PGSPQHQQDPGLESPRRQPESSPEPLRLQPKPSGGSPKCSQDQEEA-------------- HS11_PE1518 ENSG00000110104 AASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVL-------------- LOXAF71_10_PE3 ENSLAFG00000009449 PGSPHCQQDPGLESPRRQPESSPKSPLRQPKPCEES-KFSQCQGELDPELSKSKEEPGPG LOXAF71_10_PE4 ISOFORMIN PGSPHCQQDPGLESPRRQPESSPKSPLRQPKPCEES-KFSQCQGELDPELSKSKEEPGP- MACMU14_14_PE27 NOISO PGSPQRQQDLHLESPQRQPESRPESPRCQPKSSEEASKCSQDQGVL-------------- MICMUGS_3331_PE3 NOISO AGSPQRQQDLGLESLQRQPEANPESPRRQATPNEESPKFSQGLGEL-------------- MONDO5_307_PE8 ISOFORMIN LGTPKRQQNQQARGTPDEKRHGPESSQSPKKPRLGSPKTLEAQGSGGEPFSRPPPE---- MONDO5_307_PE9 ENSMODG00000020334 LGTPKRQQNQQARGTPDEKRHGPESSQSPKKPRLGSPKTLEAQGSGGEPFSRPPPE---- MOUSE19_PE549 NOISO PGSLQPHQDLGLESPAGQTESSPESPQREQP-----SKLPPPQGEL-------------- OCHPRGS_4480_PE6 NOISO PQSPPRLQDPGVESPQRQPEITPESPQRQPEPCAKTPEVSRGQGELDVLAQSTE------ OTOGAGS_3910_PE4 NOISO PRSPHRQQDLSLVSPQRWPESSPASPRRRPNPSEKSPNFSEDLREL-------------- PANTR11_62_PE6 ENSPTRG00000003721 AASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVL-------------- PIG2_10_PE18 NOISO PGSPQRQRDPGLESSQRQPESSPETPGLQSKPNGESPKFSQDQE-A-------------- PONPY11_16_PE22 NOISO AGSPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEVPKCSQDQGVL-------------- PROCAGS_6033_PE2 NOISO PLSPERQQDPGLESPRRQPESSPTSPLRQPKPSEESLKSI--PGEQ-------------- PTEVAGS_901_PE1 NOISO PGFPQSQQHPGQESPQRQPESSPETPQCQPKPSGESPKYFQSQDEP-------------- RABIT1_198_PE11 NOISO PQSPPRQQEAGLESPRRQPELNPEPPQRQPKPCGKAPGFPQGQGELDLTLARNS------ RAT1_PE3545 NOISO PGSLQLHQDLGLDSPAGQTESNPESPQREQS-----SKLSPTQ----------------- TUPGBGS_4118_PE3 NOISO PGSPQHQPDPGQASPQRLPESNPXXXXXXXXXXXXXXXXXXXXXXXX------------- TURTRGS_774_PE1 NOISO PGSPQRQRDPGLESPQRQPESSPEFSRLQPQPSGESPKFSQDREEA-------------- MATCH . CONSENSUS ??S??????????SP???PE??PE?P?????P????????????????????????????

AILMEGL193899_1_PE4 NOISO ----------------------DSELALSKKELAPGSPRHQVPLGPGSPEPYPGQQAPGP BOVIN29_40_PE9 NOISO ----------------------DSELPKSKEEPTPGCPRHQLQQDSGSLEPFPGQKAPGP CALJA11_121_PE13 ENSCJAG00000016483 ----------------------ASELAQNKEELTPGFPQHQLPPGPESPEPYPGQQAPGP CALJA2_61_PE1 NOISO ------------------------------EELPRGGGW-----VPS--NSYT------- CALJA2_62_PE30 NOISO ------------------------------EELPRGGGW-----VPS--NSYT------- CANFA18_60_PE1 NOISO -------------------------------EPAPGSPRHQPGLGP--PEPHP------- CAVPO65_10_PE4 NOISO ------------------------------------S----PKSGPGSPEPEP------- DASNOGS_1756_PE1 NOISO ----------------------NLELAQSKEEPTPGSPIHQLQPGPGSAEPYPGQQAPGP DIPORGS_5019_PE2 NOISO ----------------------DSEAAEGQEELSSGSPPGQLQPGPGSPEPYLAQQAPGP ERIEUGS_2141_PE1 NOISO ----------------------------------KEEPVHQPQPGPTSPEPHPASQAPGP FELCAGS_3606_1_PE4 NOISO ----------------------DSELALNKKELAPGSPRHQLQPGPASPEPYLGQQAPGP GORGO11_60_PE14 NOISO ----------------------ASELAQSKEELTPGAPQHQLPPVPGSPEPYPGQQASGP HORSE12_21_PE14 NOISO ----------------------DSELAQRKEKLAPGSPRHQLQPGPGSSEPYPGQPALGP HS11_PE1518 ENSG00000110104 ----------------------ASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGP LOXAF71_10_PE3 ENSLAFG00000009449 SPQRQPEPGADAPTPFRSQTGPDLELAQSKEEQAPESPRHHLQPGLGSPEPFRGQQATGP LOXAF71_10_PE4 ISOFORMIN -------------------------------------------PGLGSPEPFRGQQATGP MACMU14_14_PE27 NOISO ----------------------ASELAQSKEELTPGAPQHQLPPGPGSPEPYPGQQAPGP MICMUGS_3331_PE3 NOISO ----------------------ASDLAQSKEEPSPEAPQNQLQPGPGSPEPYPGQQAPGP MONDO5_307_PE8 ISOFORMIN --------------------------------ASPASPQSPRDKG--------------- MONDO5_307_PE9 ENSMODG00000020334 --------------------------------ASPASPQSPRDKG--------------- MOUSE19_PE549 NOISO ----------------------DSEAAHAKE-----------EVIPGSPEPCPGQQAPGP OCHPRGS_4480_PE6 NOISO ------------------------------------------ETAQGSPEPRLGQPAPGP OTOGAGS_3910_PE4 NOISO ----------------------ASELPLKKEGVPPEASLDQLQPGPRSREHSLGK-PRGL PANTR11_62_PE6 ENSPTRG00000003721 ----------------------ASELAQSKEELTPGAPQHQLPPVPGSPEPYPGQQAPGP PIG2_10_PE18 NOISO ----------------------DSELAGSKAEQTPESPQHQLQLGPGSLEPYPGQQAPDL PONPY11_16_PE22 NOISO ----------------------ASELAQSKEELTPGAPQHQLPPVPGSPEPYPGQQAPGP PROCAGS_6033_PE2 NOISO ----------------------DPELADSKEEPVQGSPRYQPEPVPGSPEPCPGQQATGP PTEVAGS_901_PE1 NOISO ----------------------DAELAQSKEKLAPGAPRYQLHPGPGLPEPYLGQLAPGP RABIT1_198_PE11 NOISO ------------------------------------------DRSRYQPH--L------- RAT1_PE3545 NOISO ----------------------DSEVAHAKE-----------EVIPRSPEPCPGQQAPGP TUPGBGS_4118_PE3 NOISO -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGQQAPGP TURTRGS_774_PE1 NOISO ----------------------DSESPKSKEEPTPGSPRHQLQPSPGSLEPYPGRQAPGP MATCH CONSENSUS ?????????????????????????????????????????????????E??????????

AILMEGL193899_1_PE4 NOISO EPSRPLQE-----PTAQSPGSPRGQHEPSKPPPAVETVRSCPG------AKKRKSSSAHA BOVIN29_40_PE9 NOISO EPSKPLQE-----LTPRSPGSPRDQHEPSKPPAAGEPAREGPA------PKKREGSSAQA CALJA11_121_PE13 ENSCJAG00000016483 EPSQPLLE-----LTPETPGSPRGQHEPSKPPPAGETVTGVFG------AKKRKGSSSQA CALJA2_61_PE1 NOISO ----------------------WAQ-DHQSLTPVSKCQGEVRGSHG---AKKQKGSSAQA CALJA2_62_PE30 NOISO ----------------------WAQ-DHQSLTPVSKCQGEVRGSHG---AKKQKGSSAQA CANFA18_60_PE1 NOISO ----------------------------------ARTGSSDLG------AKKRTGPAAHA CAVPO65_10_PE4 NOISO --VQPGEE-----PTPRIPGPSRSQQGPSEPRPAAETVPGGGGDDS---AEKRHRPSGRS DASNOGS_1756_PE1 NOISO EPSRPPQE-----LTPLSPDSLRDQQEPSKPLPFVETVTGDLG------AKKRRGSSAQA DIPORGS_5019_PE2 NOISO EPSQPQQE-----LTPQAPCSPERQQEPHKPPVAGPTVTGSLG------AKKRKGSSAQT ERIEUGS_2141_PE1 NOISO EPSRPLQE-----LAPRSPGSP------GRPPATGETARDGPG------AQKRKGAAAQA FELCAGS_3606_1_PE4 NOISO EPSRPLQE-----LTAQSPGSPRGQHEPSKPPPAGETVRSGLG------AKKRTSSSAQA GORGO11_60_PE14 NOISO EPSQPLLE-----LTPRAPGSPRGQHEPSKPPPAGETVTGGFG------AKKRKGSSSQA HORSE12_21_PE14 NOISO EPSPPLQE-----LTPRSPGSPWGRHEPSKPPAAGEP-------------KKRRGSSPQA HS11_PE1518 ENSG00000110104 EPSQPLLE-----LTPRAPGSPRGQHEPSKPPPAGETVTGGFG------AKKRKGSSSQA LOXAF71_10_PE3 ENSLAFG00000009449 EPSQPLQE-----LTPQSPGSPRGPHDPSKPTLAGETVPGGVG------AKKRRGSSAQA LOXAF71_10_PE4 ISOFORMIN EPSQPLQE-----LTPQSPGSPRGPHDPSKPTLAGETVPGGVG------AKKRRGSSAQA MACMU14_14_PE27 NOISO EPSQPLLE-----LTPKAPGSPRGQHEPSKPPPAGETVTGGLG------AKKRKGSSSQA MICMUGS_3331_PE3 NOISO EPSRPLQE-----LTPEAPGSPQGQHEPSKPPPVGETVTGGLG------EKKRKSSSAQD MONDO5_307_PE8 ISOFORMIN ------------------SGSQKGQPEPGTESSLGQPEPDGAAENLAPKTKKRGGSPSPT MONDO5_307_PE9 ENSMODG00000020334 ------------------SGSQKGQPEPGTESSLGQPEP------------KRGGSPSPT MOUSE19_PE549 NOISO EPSQPAQE-----LTVQAPSSPERQLEPGKLPPAGETVTESLN------LKKRVIASPQA OCHPRGS_4480_PE6 NOISO EPSRPPVP-----------------LEPRRPLPAGRTVASRPR------AKEPHDSCAQT OTOGAGS_3910_PE4 NOISO EPSHPLEE-----LNTDALGSPRGQXXXXXXXXXXXXXXXXXX------XXXXXXXXXXX PANTR11_62_PE6 ENSPTRG00000003721 EPSQPLLE-----LTPRAPGSPRGQHEPSKPPPAGETVTGGFG------AKKRKGSSSQA PIG2_10_PE18 NOISO EPSQPLQELPLQELPLQSPGSPQDQNEPSKPAPSRERGRDVLG------PKKRESSSVQA PONPY11_16_PE22 NOISO EPSQPLLE-----LTPRAPGSPRGQHEPSKPPPAGETVTGGFG------AKKRKGSSSQA PROCAGS_6033_PE2 NOISO EPSQPLQE-----LTPQSPGSLRGQHEPSKPTPGWETVPGGDG------AKKRRSSLAQA PTEVAGS_901_PE1 NOISO EPSPPLQD-----LSPPSPDYPRGEHEPNKPPPAREPVSDGLG------PKKRKGSSAQA RABIT1_198_PE11 NOISO --------------------------ETRM----------------------QSSVSMES RAT1_PE3545 NOISO EPSQPAQE-----LAFQAPSSPERQLEPSKLPPAGESVTGSLD------LKKRVIASPQA TUPGBGS_4118_PE3 NOISO EPSKPPHE-----LTPRAPVFPRGQQEPSKLPLTGETVTGGLG------AEKRKDSKAQA TURTRGS_774_PE1 NOISO EPSQPLQE-----LTPQSPGSPRDQREPSKPPPPGQPERDGLG------PKKREGSSAQA MATCH CONSENSUS ????P??????????????????????P??????????????????????KKR???????

AILMEGL193899_1_PE4 NOISO PASKKLKEGEE--VPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQQKMKERQERK BOVIN29_40_PE9 NOISO PASKKPKE--E--IPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKDRQERK CALJA11_121_PE13 ENSCJAG00000016483 PASKKLKEE-K--LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLHTSWQRKMKERQERK CALJA2_61_PE1 NOISO PVSKKLKEA-EEEFPIIQKGRPKLGWVWKDHSKERFSQMVQDKHLHTCWQRKMKEQQERK CALJA2_62_PE30 NOISO PVSKKLKEG-EEEFPIIQKGRPKLGWVWKDHSKERFSQMVQDKHLHTCWQRKMKEQQERK CANFA18_60_PE1 NOISO AASKKLKEVE--AALVIPKGKPQSGRLWKDGSKKRFSQMVQSKPLRTSWQQKMKERQERK CAVPO65_10_PE4 NOISO PAPKKRKGEREEALPVIPKGRPKSGRVWKDRAKKRFSHMVQDKPLHTSWQRKMKERQERK DASNOGS_1756_PE1 NOISO PASKKLKEE-EEEVPMIPKGKPKSGRVWKDRSKKXXXXXXXXXXXXXXXXXXXXXXXXXX DIPORGS_5019_PE2 NOISO PASKILKKE-EEECPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK ERIEUGS_2141_PE1 NOISO PPSKKLKEEVE--VPIIPRGKPSRGRVWNDRXXXXFSQMVQDKPLRTSWQRKMKERQERK FELCAGS_3606_1_PE4 NOISO PASKKLKEVEE--VPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKDRQERK GORGO11_60_PE14 NOISO LASKKLNKE-E--LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERK HORSE12_21_PE14 NOISO PASKKLK-E-E--VPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK HS11_PE1518 ENSG00000110104 PASKKLNKE-E--LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERK LOXAF71_10_PE3 ENSLAFG00000009449 PASKMLKKEVEEVPMMIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK LOXAF71_10_PE4 ISOFORMIN PASKMLKKEVEEVPMMIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK MACMU14_14_PE27 NOISO PASKKLNKE-E--LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERK MICMUGS_3331_PE3 NOISO PVCKKLKEE-KEELPVIPKGKPKSGRVWKDRSKKXXXXXXXXXXXXXXXXXXXXXXXXXX MONDO5_307_PE8 ISOFORMIN SAPKK---PKPKEVPVIPKGKPKSGRVWKDPKKKRFSQMVQDKPLKTSWERKMKERQERK MONDO5_307_PE9 ENSMODG00000020334 SAPKK---PKPKEVPVIPKGKPKSGRVWKDPKKKRFSQMVQDKPLKTSWERKMKERQERK MOUSE19_PE549 NOISO PASKKLKEKEE--LPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK OCHPRGS_4480_PE6 NOISO PAFKKLKKE-EEEVPVIPMGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERR OTOGAGS_3910_PE4 NOISO ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSQMVQDKPLHTSQK----MKRQRK PANTR11_62_PE6 ENSPTRG00000003721 LASKTLNKE-E--LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERK PIG2_10_PE18 NOISO PASKKQKKE-E--VPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK PONPY11_16_PE22 NOISO PASKKLNKE-E--LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERK PROCAGS_6033_PE2 NOISO PGSKKLKKE-AEEFPMIPKGKPKSGRVWKDRSKKXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_901_PE1 NOISO PASKTLKEEVA--IPTIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK RABIT1_198_PE11 NOISO EVXK--KLK-KEQIPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK RAT1_PE3545 NOISO PASKKLK--EE--LPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK TUPGBGS_4118_PE3 NOISO PASKKLKKE-EEELPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERK TURTRGS_774_PE1 NOISO AASKKPXXXXXXXXXX---XXXXXXXXXXXXXXXXFSQMVQDKPLRTSWQQKMKDRQERK MATCH CONSENSUS ???K??????????P?IPKGKPKSGRVWKD?SKKRFSQM?QDKPL?TSWQ?KMK?RQERK

AILMEGL193899_1_PE4 NOISO LAKDYARHLEEEKEKRRQEKKQRRAENLKRRLENERRAEVVQVIRNPAKLKRAKKKQLRS BOVIN29_40_PE9 NOISO LAKDFARHLEEEKERRRQEKKKRRAENLRRRLENERKAEIVQVIRNPAKLKRAKKKQLRS CALJA11_121_PE13 ENSCJAG00000016483 LAKDFARRLEEEKERRRQEKKQRRAENLKRRLENERKAEIVQVIRNPAKLKRAKKKQLRS CALJA2_61_PE1 NOISO MAKDSAPHRRKGATRRR----NSTAKNVKRRLKNERKAEIVQVIQNPTKLKLVKQKQLHS CALJA2_62_PE30 NOISO MAKDSAPHRRKGAARRR----NAPAKNVKRRLKNERKAEIVQVIQNPTKLKPGKQKQLHS CANFA18_60_PE1 NOISO LAKDLARHLEEEKEKRQQEKKQRRAENLKRRLENERRAEVVQVIRNPAKLKRAKKKQLRS CAVPO65_10_PE4 NOISO LARDFARHLEEEKARRRQEKKQRRAENLRRRQENERRAEVVQVIRNPAKLKRAKKKQLRS DASNOGS_1756_PE1 NOISO XXXXXXXXXXXXXXXXXXEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS DIPORGS_5019_PE2 NOISO LAKDFARHLKEEKERRRQEKKQRRAENIKRRLENERKAEIVQVIRNPAKLKRAKKKQLRT ERIEUGS_2141_PE1 NOISO LAKDFARHLEEEKERRRQEKKQRRAENLRRRLENERKAEVVQVIRNPTKLKRAKKKQLRS FELCAGS_3606_1_PE4 NOISO LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENARRAEVVQVIRNPAKLKRAKKKQLRS GORGO11_60_PE14 NOISO LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS HORSE12_21_PE14 NOISO LAREFARHLDEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS HS11_PE1518 ENSG00000110104 LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS LOXAF71_10_PE3 ENSLAFG00000009449 LAKDFARHLEEEKERRRQEKKQRRAENLRRRLENERRAEVVQVIRNPAKLKRAKKKQLRT LOXAF71_10_PE4 ISOFORMIN LAKDFARHLEEEKERRRQEKKQRRAENLRRRLENERRAEVVQVIRNPAKLKRAKKKQLRT MACMU14_14_PE27 NOISO LAKDFARHLEEEKERRRQEKKQRKAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS MICMUGS_3331_PE3 NOISO XXXXXXXXXXXXXXXXXXEKKQRRAENLKRRLENERKAEIVQVIRNPAKLKRAKKKQLRS MONDO5_307_PE8 ISOFORMIN LAKDFARHLEEEKQRCKEDKKRRRAENLKRRLENERKAEIVQVIRNPAKLKRAKKKQLRR MONDO5_307_PE9 ENSMODG00000020334 LAKDFARHLEEEKQRCKEDKKRRRAENLKRRLENERKAEIVQVIRNPAKLKRAKKKQLRR MOUSE19_PE549 NOISO LAKDFARHLEEEKQRRRQEKKERRAENLRRRLENERKAEIVQVIRNPAKLKKAKKKQLRS OCHPRGS_4480_PE6 NOISO LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKIKRAKKKQLRS OTOGAGS_3910_PE4 NOISO LAKDFARHLEEEKQRRRQEK-QCRAENLKRRLENERKAEIVQVIRNPAKLKRAKKKQLRS PANTR11_62_PE6 ENSPTRG00000003721 LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS PIG2_10_PE18 NOISO LTKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS PONPY11_16_PE22 NOISO LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS PROCAGS_6033_PE2 NOISO XXXXXXXXXXXXXXXXXXEKKQRRAENLRRRLENERKAEVVQVIRNPAKLKRAKKKQLRG PTEVAGS_901_PE1 NOISO LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS RABIT1_198_PE11 NOISO LTKEFARHLEEEKEQRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRS RAT1_PE3545 NOISO LAKDFARHLEEEKQRRRQEKKERRAENLRRRLENERKAEIVQVIRNPAKLKKAKKKQLRS TUPGBGS_4118_PE3 NOISO LAKDFARHLEEEKERRRQEKKQRRAENLRRRLENERKAEVVQVIRNPAKIKRAKKKQLRS TURTRGS_774_PE1 NOISO QAKDFARHLQEEKERRRQEKKQRRAENLKRRLENERKAEIVQXIRNPAKLRRAKKQQLRS MATCH . *:*::** :* *:**:** *:**:*:: *::**: CONSENSUS LAKD?ARHL?EEK?RRR?EKK?RRAENL?RRLENERKAE?VQVIRNPAKLKRAKKKQLRS

AILMEGL193899_1_PE4 NOISO IQKRDTLALLQKQPPQWPAAKI BOVIN29_40_PE9 NOISO IEKRDTLAQLQKQPPQRPATKV CALJA11_121_PE13 ENSCJAG00000016483 VEKRDTLALLQKQPPPQPATKI CALJA2_61_PE1 NOISO TEKQDTLALLQKQEPQQPAAKI CALJA2_62_PE30 NOISO TEKQDTLALLQKQDPRQPAAKI CANFA18_60_PE1 NOISO IQKRDTLALLQKQPSQQPAAKI CAVPO65_10_PE4 NOISO IMKRDTLALLQKQPPRQLAANT DASNOGS_1756_PE1 NOISO VEKRDTLALLQKQPPQRPAAKI DIPORGS_5019_PE2 NOISO IAKRDTLTLLQKQPPQQQV--- ERIEUGS_2141_PE1 NOISO IQKRDTLTLLQKTPPQRPPPKV FELCAGS_3606_1_PE4 NOISO IEKRDTLALLQKQPPQRPAAKV GORGO11_60_PE14 NOISO IEKRDTLALLQKQPPQQPAAKI HORSE12_21_PE14 NOISO IEKRDTLALLQKQPPQRPAAKV HS11_PE1518 ENSG00000110104 IEKRDTLALLQKQPPQQPAAKI LOXAF71_10_PE3 ENSLAFG00000009449 IEKRDTLVLLQKQPPQRAAAKN LOXAF71_10_PE4 ISOFORMIN IEKRDTLVLLQKQPPQRAAAKN MACMU14_14_PE27 NOISO IEKRDTLALLQKQPPQRPAAKI MICMUGS_3331_PE3 NOISO IEKRDTLALLQKQPPQRPTAKI MONDO5_307_PE8 ISOFORMIN IEKRDTLALLQKQPPQRPVAK- MONDO5_307_PE9 ENSMODG00000020334 IEKRDTLALLQKQPPQRPVAKE MOUSE19_PE549 NOISO IEKRDTLALLQKQPPQRPVAKV OCHPRGS_4480_PE6 NOISO IEKRDTLALLQKQPPQRPAVQV OTOGAGS_3910_PE4 NOISO IEKRDTLALLQKQPPQQPAAKI PANTR11_62_PE6 ENSPTRG00000003721 IEKRDTLALLQKQPPQQPAAKI PIG2_10_PE18 NOISO IEKRDTLAQLQKQPPQRPAAKI PONPY11_16_PE22 NOISO IEKRDTLALLQKQPPQRPAAKI PROCAGS_6033_PE2 NOISO IEKRDTLVLLQKQPPQQPAAKN PTEVAGS_901_PE1 NOISO IEKRDTLALLHKQPPQRPAAGV RABIT1_198_PE11 NOISO IEKRDTLALLQKQPPQRPAAKV RAT1_PE3545 NOISO IQKRDTLALLQKQPPQRPVAKV TUPGBGS_4118_PE3 NOISO IQKRDTLALLQKQPPQRPAAKV TURTRGS_774_PE1 NOISO IEKRDTLAQLQEQPPRRPAAKV MATCH *:***. *:: . CONSENSUS I?KRDTLALLQKQPPQ?P?AK?


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