Alignment of the gene Family HOG000112367 of HOGENOM

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Threshold: 50% 80% 100%
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Isoforms are OFF
AILMEGL192678_1_1_PE11 NOISO ------------------------------------------------------------ BOVIN6_91_PE10 NOISO ------------------------------------------------------------ CALJA3_131_PE14 ENSCJAG00000014627 ------------------------------------------------------------ CANFA13_64_PE23 NOISO ------------------------------------------------------------ CAVPO47_4_PE5 NOISO ------------------------------------------------------------ DASNO2495_PE3 NOISO ------------------------------------------------------------ DIPORGS_2762_PE1 NOISO ------------------------------------------------------------ ERIEUGS_3624_PE1 NOISO ------------------------------------------------------------ GORGO4_82_PE22 NOISO ------------------------------------------------------------ HORSE3_67_PE10 NOISO ------------------------------------------------------------ HS4_PE1449 NOISO ------------------------------------------------------------ LAMPAGS_3260_1_PE3 NOISO ------------------------------------------------------------ LOXAF30_28_PE11 NOISO ------------------------------------------------------------ MACMU5_61_PE10 NOISO ------------------------------------------------------------ MICMUGS_4254_PE3 NOISO ------------------------------------------------------------ MONDO5_19_PE8 NOISO ------------------------------------------------------------ MOUSE5_PE1333 NOISO ------------------------------------------------------------ MYOLUGS_5518_PE3 NOISO ------------------------------------------------------------ OCHPR4304_PE3 NOISO ------------------------------------------------------------ ORNANULTRA362_3_PE5 ENSOANG00000013692 ------------------------------------------------------------ OTOGAGS_5066_PE4 NOISO ------------------------------------------------------------ PANTR4_62_PE8 NOISO ------------------------------------------------------------ PIG8_59_PE8 ENSSSCG00000008938 ------------------------------------------------------------ PONPY4_76_PE4 NOISO ------------------------------------------------------------ PROCA5980_PE1 NOISO ------------------------------------------------------------ PTEVAGS_3629_PE3 NOISO ------------------------------------------------------------ RABIT15_81_PE10 NOISO ------------------------------------------------------------ RAT14_PE303 NOISO CLAPWLSVASAVCSHFYHRLLRTYFKDRLTRFKFTFYIVQLLSGIGSHPNLKAPKIKLDC SORARGS_2951_PE1 NOISO ------------------------------------------------------------ SPETR123914_PE1 NOISO ------------------------------------------------------------ TARSYGS_3427_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5264_PE3 NOISO ------------------------------------------------------------ TURTRGS_3203_1_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192678_1_1_PE11 NOISO --------------MLLLQYRHGASLPKLDNLVPSGKMKILLVFLGLLGNSVAMPF-QMQ BOVIN6_91_PE10 NOISO --------------KMLLQCRHEASSPKLDYLVPSGKMKILLVFLSLLGYSIAMPL-QMH CALJA3_131_PE14 ENSCJAG00000014627 -----------------MLVLHGASFPKLDNLVPNGKMKILLVFLGLLGNSVAMPM---H CANFA13_64_PE23 NOISO --------------MLLFQYRHGASLPKLDNLVPTGKMKILLVFLGLLGNSFAMPY-QMQ CAVPO47_4_PE5 NOISO --------------MRLLHCRKGASFPKLYNLVPNGKMKMLLVFLGLLGNSAAMPM---Y DASNO2495_PE3 NOISO ------------------------------------------------------------ DIPORGS_2762_PE1 NOISO --------------MLLLQCRNRISFPKLHNLVPSGKMKILVXXXXXXXXXXXXXX---X ERIEUGS_3624_PE1 NOISO ------------------------------------------------------------ GORGO4_82_PE22 NOISO --------------MLVLRCRLGTSFPKLDNLVPKGKMKILLVFLGLLGNSVAMPM---H HORSE3_67_PE10 NOISO ------------------------------------------------------------ HS4_PE1449 NOISO --------------MLVLRCRLGTSFPKLDNLVPKGKMKILLVFLGLLGNSVAMPM---H LAMPAGS_3260_1_PE3 NOISO --------------------------------VPSGKMKILLVFLGLLGYSAAMP---MQ LOXAF30_28_PE11 NOISO --------------MLLLQCRPGASFSKLDNLASNGKMKILLVFLGLLGNSIAMPF-QMQ MACMU5_61_PE10 NOISO --------------MLVLRCRDGTSFPKLDNLVPKGKMKILLVFLGLLGNSVAMPM---H MICMUGS_4254_PE3 NOISO --------------------------------VPRGKMKILLVFLGLLGNSIAMAX---X MONDO5_19_PE8 NOISO --------------------------------VPRGKMKTLLMFLSLFSCSIAMPM---Q MOUSE5_PE1333 NOISO --------------MLLLQCRNPTSPPKPCGLVPNVKMS-LLVFLGLLGVSAAMPF-QMP MYOLUGS_5518_PE3 NOISO ------------------------------------------------------------ OCHPR4304_PE3 NOISO ------------------------------------------------------------ ORNANULTRA362_3_PE5 ENSOANG00000013692 --------------SILLKSRLFDGFPCIA-RIARGKMKSFLLFLGLFGASTAMP---MH OTOGAGS_5066_PE4 NOISO ------------------------------------------------------------ PANTR4_62_PE8 NOISO -------------------------------------------------------M---H PIG8_59_PE8 ENSSSCG00000008938 --------------KMLLSCRHGASSPKLDNLVPSGKMKILLVFLGLLCYSAAMPD-DLK PONPY4_76_PE4 NOISO --------------MLVLRCRLGTSFPKLDNLVPKGKMKILLVFLGLLGNSVAMPM---H PROCA5980_PE1 NOISO -----------------------------------SSKMKLLVFLGLLGNSIAMP---MQ PTEVAGS_3629_PE3 NOISO ---------------MLLQCRHGASSSKLDNLVPSGKMKILLIFLGLLGNSIAMP---MQ RABIT15_81_PE10 NOISO --------------MLLLWYRNGASFPELDNLVPSGKMKILLTFLGLLGNAMAMPM---H RAT14_PE303 NOISO EDPLIRAYESFGENMLLLQCRNTASPPKPCDM---VKMS-LLVFLGLLGVSAAMPV-SIL SORARGS_2951_PE1 NOISO --------------MLLLPCRYGASCPKLDHFVPSGNMKILLVFLGLLGYSTAMP---MQ SPETR123914_PE1 NOISO ------------------------------------------------------------ TARSYGS_3427_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5264_PE3 NOISO ------------------------------------------------------------ TURTRGS_3203_1_PE1 NOISO ---------------MLLHCRHEASSPKLDNLVPSGKMKSVLVFLGLLCYSIAMP---MQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192678_1_1_PE11 NOISO MPRM-PGFSSKSEEMMRYGQFNFMNSPHMA-QLGPLYGNGM------PPVFPQYQM-PMW BOVIN6_91_PE10 NOISO MPRI-PGFSSKSEEMMRYGHFNFMNFPHLA-HLSPFYGNGIQL----PQLFPQYQM-PMW CALJA3_131_PE14 ENSCJAG00000014627 MPRM-PGFSSKSEEMMRYNQFNFMNSPHMA-HLGPFFGNGLQL----PQQFPQYQM-PMW CANFA13_64_PE23 NOISO MPRM-PGFSSKSEEMMRYGQFNFMNSPHMA-QLGPLYGNSM------PQLFPQYQM-PMW CAVPO47_4_PE5 NOISO MPRM-PGFSSKSEEMMRYGQFNYMHPPPLGNKIVPFSGNGYQI----PPPYPQYPMPPMW DASNO2495_PE3 NOISO ----------------------------MG-HLGPVYGNGIQF----PQLFPQYQM-PMW DIPORGS_2762_PE1 NOISO XXXX-XXXXXXXXXMMRYGQFNFMSPPYMA-L---SYGNGLQF----PQQFPQFQM-PMW ERIEUGS_3624_PE1 NOISO ------------------------------------------------------------ GORGO4_82_PE22 NOISO MPRM-PGFSSKSEEMMRYNQFNFMNGPHMA-HLGPFFGNG--L----PQQFPQYQM-PMW HORSE3_67_PE10 NOISO ------------------------------------------------------------ HS4_PE1449 NOISO MPRM-PGFSSKSEEMMRYNQFNFMNGPHMA-HLGPFFGNG--L----PQQFPQYQM-PMW LAMPAGS_3260_1_PE3 NOISO MPRI-PGFSSKSEEMMRYGHFNFMNSPHXX-XXXXXXXXXXXX----XXXXXXXXX-XXX LOXAF30_28_PE11 NOISO MPRM-PGFSSKSEEMMRYGQFHFMNSPHMS-QLGPLYGNGLQH----PQPFPQYQV-PMW MACMU5_61_PE10 NOISO MPRM-PGFSSKSEEMMRYNQFNFMTLPHLA-HLGPFFGNS--L----PQQFPQYQM-PMW MICMUGS_4254_PE3 NOISO XXXX-XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX----XXXXXXXXX-XXX MONDO5_19_PE8 NOISO MPRM-GGFGSKSEEMMRYGQYSFMNMPHMA-HLGPLYGYNIRL----PQQFPQIQM-PVW MOUSE5_PE1333 NOISO MPRM-PGFSSKSEEMMRYNQFNFMNAPPMM-PMGP-YGNGMPMPPHMPPQYPPYQM-PMW MYOLUGS_5518_PE3 NOISO ----------------------------MT-QLGPSYGYGMQP----PQLFPQYQM-PMW OCHPR4304_PE3 NOISO -------------------------MPP----MG-PYGNGFPF----PQQFPPYQM-PMW ORNANULTRA362_3_PE5 ENSOANG00000013692 MPRM-PGFGSKSEEMMPYGQYNFMNSPHMA-QLGPLYGYGLQL----PQFFQPPQM-PPW OTOGAGS_5066_PE4 NOISO ------------------------------------------------------------ PANTR4_62_PE8 NOISO MPRM-PGFSSKSEEMMRYNQFTFMNGPHMA-HLGPFFGNG--L----PQQFPQYQM-PVW PIG8_59_PE8 ENSSSCG00000008938 EERTLTLKLSSQGKMMRYGHFNFMNAPHMA-HLGTLYGNGMQL----PQFFPQYQM-PMW PONPY4_76_PE4 NOISO MPRM-PGFSSKSEEMMRYNQFNFMNGPHMA-HLGPFFGNG--L----PQQFPQYQM-PMW PROCA5980_PE1 NOISO MPRM-PGFSSKSEEMMRYGHFSFMNSPHMS-QLGPMYGNGLQL----PQPFPQ--M-PMW PTEVAGS_3629_PE3 NOISO MPRM-PGFSSKSEEMMQYSQFNFMNSPHLA-QLGPLYGNGLQL----PQLFPQYQM-PMW RABIT15_81_PE10 NOISO MPRM-PGFSSKSEEMMRYGPFPFMNYPHMS-PMGP-YGNGFQF----PQQFPPYQM-PMW RAT14_PE303 NOISO --SV-LGISFVPREMMRYNQFNFMNAPPMM-HMGP-WQNGLPMPPHMPPQYPPYQM-PMW SORARGS_2951_PE1 NOISO MPRM-RGFSSKSEEMMRFNQF-FMNSPHMS-QLGPMYGDGM------PQLFPQYHM-PMW SPETR123914_PE1 NOISO ------------------------------------------------------------ TARSYGS_3427_PE1 NOISO ----------------------------MA-HLNPMYGN---V----PQQFPQYQM-PMW TUPGBGS_5264_PE3 NOISO ----------------------------LA-HLGPMYGNGLQL----PPQFPQYQM-PMW TURTRGS_3203_1_PE1 NOISO MPRM-PGFSSKSEE-MRYGHFNFMS-PPMV-HLGPLYGNGMQL----PQLFLPYQM-PMW MATCH CONSENSUS ???????????????????????????????????????????????P?????????P?W

AILMEGL192678_1_1_PE11 NOISO PQPPPNMGHPQKPSTPSAPKRQKSKTDQVPETQNPNQPQPKKP----PPKQPLKQPPPTP BOVIN6_91_PE10 NOISO PQPPPNKKSPQKPSSPAAPK----QTDQAPETPSPNQPQPTDS----PPNQHLKQPSTTT CALJA3_131_PE14 ENSCJAG00000014627 PHPPPNTLNPQKPSGPK----RHNKTDQTQETQKPNQTQSKKP----PQKRPLKQPSHTP CANFA13_64_PE23 NOISO PQPPPNTGHPQKS--PSALKRQKSKTDQAPETQKPNQPQPKKP----PPKRPLKQPPPTP CAVPO47_4_PE5 NOISO PHPLPSGWQN--PPVPQ----HQTKTDQNQETQKPNQTQPQKP----PEKQPSNQPPENP DASNO2495_PE3 NOISO PHPPPNTWHPQKPSPPSAPKHH-SKTGQAQGTQKTNQPESKKP----PPKRPLKQPLHAP DIPORGS_2762_PE1 NOISO PQPPPSAWQN--PPTPK----HQGNNDHTPDTQKPNQTETNTP----TQKQPSTSPPHEP ERIEUGS_3624_PE1 NOISO ------------------------------------------------------------ GORGO4_82_PE22 NOISO PQPPPNTWHPRKSSAPK----RHNKTDQTQETQKPNQTQSKKP----PQKRPLKQPSHNQ HORSE3_67_PE10 NOISO ---------------------------------------PKKS----PPKQ------PAQ HS4_PE1449 NOISO PQPPPNTWHPRKSSAPK----RHNKTDQTQETQKPNQTQSKKP----PQKRPLKQPSHNQ LAMPAGS_3260_1_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX-----XXXXXX----XXXXXXXXXXXXX LOXAF30_28_PE11 NOISO PQPPPNTWRPKKPSGPSGLKRQ-SKTNQIQETPKPNQPQPKMP----SPKQPLKQPTQDP MACMU5_61_PE10 NOISO PQPP--PWHPQKPSAQK----RHNKTDQTQETQKPNQTQSKKP----PQKRPLKQPSHTP MICMUGS_4254_PE3 NOISO XXXX--XXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXX MONDO5_19_PE8 NOISO PQPPPNAWLPRMPPNLP---RPQIKAGEGQEIPRPSQPLPTKPPT--TPKPPTKQSPEGP MOUSE5_PE1333 NOISO PPPVPNGWQQ--PPMPN----FPSKTDQTQETAKPNQTNPQEP-Q--PQKQPLKEPPNEA MYOLUGS_5518_PE3 NOISO PQPPPNTGRPKKPSSPPASKRQ-GKTDLAPETPKPNQPQPKRS----PPKRPLKQPTPAP OCHPR4304_PE3 NOISO PQPPPNMWPPPKPAGFR----RQSNTDQAQDTGNPNQPPTEKP----PVKDPAQQPT-TP ORNANULTRA362_3_PE5 ENSOANG00000013692 PQPPPNGWPAQNPGPPQGGK-PQAKPGQSQNTKQPNPSQPKKPPQQQPPKQAAKQPAPGP OTOGAGS_5066_PE4 NOISO ------------------------------------------------------------ PANTR4_62_PE8 NOISO PQPPPNTWHPRKSSAPK----RHNKTDQTQETQKPNQTQSKKP----PQKRPLKQPSHNQ PIG8_59_PE8 ENSSSCG00000008938 PQPPPNKKHPQKPSAS----KQQSKTDPAPESQKPNQPQPKTP----TPKQPLNEPSPTP PONPY4_76_PE4 NOISO PQPAPNTWHPRKSSAPK----RHNKTDQTQETQKPKQTQSKKP----PQKQPLKQPSHNQ PROCA5980_PE1 NOISO PQPPPNTWRPKKPSFPSGLRRR-NKADQIQETPKPNPSSPKRP----LPKQLTKQPPQDP PTEVAGS_3629_PE3 NOISO PQPPLNTRHPRKPSSPSAPKHQ-SKTDQAPESQKPNQPQPKKP----SPKRPLKQPTPAP RABIT15_81_PE10 NOISO PQPPPNMWLPPKPAGFR----RQSNTDQAQETQKPNETQTKTE----Q--QPVNQPP-TP RAT14_PE303 NOISO PPPVPNGWQQ--PPMPN----FPSKTEQTQETAKPNQTDPQEP-Q--PQKQPLKEPPNEA SORARGS_2951_PE1 NOISO PQPPPHMGHPPKSPTPH------HKTDQTQETPKPTQSPPPKT----SKQPAQQSQTTTP SPETR123914_PE1 NOISO ------------------------------------------------------------ TARSYGS_3427_PE1 NOISO PQPPPNTWHLQKPLGPK----RQNKTDPTQETQKPNQTPPKKP----PQKRPLKQPPRAP TUPGBGS_5264_PE3 NOISO PQPPPKMWPPQKPSGPK----RQSKTDQAQETQKPNQSPPKKP----PQKRPVKQPPSAP TURTRGS_3203_1_PE1 NOISO PQPPPNKKRPQKPSSPSAPKHQ-SKTDQAPETQKPNQPQLKQP----LPEHPLKQPSPTP MATCH CONSENSUS P?P?????????????????????????????????????????????????????????

AILMEGL192678_1_1_PE11 NOISO AQPE-EETQPPQAFPPFGNGLFPPFSNGLYQQPPWQVPHRVP--PGYGRPPGSNEE-GGN BOVIN6_91_PE10 NOISO AQPQEEETQTPQAFPPFGNGLFP------YQQPPWHIPHKIP--PGFGRPPGSNEE-GGN CALJA3_131_PE14 ENSCJAG00000014627 AQPK-EEDQPPQAFPPFGNGLFP------YQQPPWQIPQRVP-PPGYGRPPISNEE-GGN CANFA13_64_PE23 NOISO AQPE-EEGQPPQAFPPFGNGLF------LYQQPPWQVPHRVP--PGYGRPPASNEE-GGN CAVPO47_4_PE5 NOISO PKDK-ADAQPPQPFPPFNNGLFP------FQQPPWPIPQRMP-PPGYGRPPLSNED-GGN DASNO2495_PE3 NOISO TQPQ-EEPSPPQEFPPFANGLFP------YQQPPWQMPQRIP--PGYGRPPISNEE-GGN DIPORGS_2762_PE1 NOISO TQGK-EEAPPPQPFPPFGNGLFP------FQQPPWPIPQRVP-PPGFGRPPLSSEDGGGN ERIEUGS_3624_PE1 NOISO ---------------------------------------RIP--PGFGRPPGSNEE-GGN GORGO4_82_PE22 NOISO PQPE-EEAQPPQAFPPFGNGLFP------YQQPPWQIPQRLP-PPGYGRPPISNEE-GGN HORSE3_67_PE10 NOISO TQAE-EEAQPPQAFPPFGNGLFP------YHQPPWQVPHRLP--PGYGRPLGSNEE-GGN HS4_PE1449 NOISO PQPE-EEAQPPQAFPPFGNGLFP------YQQPPWQIPQRLP-PPGYGRPPISNEE-GGN LAMPAGS_3260_1_PE3 NOISO XXXXXXXXXXXXAFLPFGNGLFP------YQQPPWHVPHRVP--TGYGRPPVSNEE-GGN LOXAF30_28_PE11 NOISO PQPT-EETQPARAFPPFQNGLFP------YQRPPWQVGQRVP--PGYGRPPISNEE-GGN MACMU5_61_PE10 NOISO AQPE-EEAQPPQAFPPFGNGLFL------YP-PPWQIPQRLP-PPGYGRPPASNEE-GGN MICMUGS_4254_PE3 NOISO XXXX-XXXXXXXAFPSFGNGLFP------YHQPPWQIPQRLPPPPGYGRPPASNEE-GGX MONDO5_19_PE8 NOISO PRPK-EEDQQPPQYPPFGNGMFP------FHQPPWHIPQRMP--PGYGRPPVSNEE-GGN MOUSE5_PE1333 NOISO ARAK-DDAQPPQPFPPFGNGLYP------YPQPPWPIPQRGP-PTAFGRPKFSNEE--GN MYOLUGS_5518_PE3 NOISO TPPQ-EEAQPPQAFPPFGNGIFP------YQQPPWQVPHRVP--PGYGRPPVSNEE-GGN OCHPR4304_PE3 NOISO TPAK-EETQPTQAYPPFNNGLFP------YQQPPWPFPPRMP-PPGYGR--LSNEE-SGN ORNANULTRA362_3_PE5 ENSOANG00000013692 SKPT-EETRQPQMYPPFGNGFFP------FQLQPWQIPPQMP--PGYGRPPGSNEE-GGN OTOGAGS_5066_PE4 NOISO ---------------------------------------RGP-PPGYGRPPVSNEE-GGN PANTR4_62_PE8 NOISO PQPE-EEAQPPQAFPPFGNGLFP------YQQPPWQIPQRLP-PPGYGRPPMSNEE-GGN PIG8_59_PE8 ENSSSCG00000008938 TQPE-EETQTPQAFPPFGNGLFP------YQQPLWHVPHRIP--PGYGRPPTSNEE-GGN PONPY4_76_PE4 NOISO AQPK-EEAQPPQAFPPFGNGLFP------YQQPPWQIPQRLP-PPGYGRPPISNEE-GGN PROCA5980_PE1 NOISO PQPT-EETQPTQAFPPFPNGLFP------YHPPPWQVGQRVP--PGYGRPPNSNEE-GGN PTEVAGS_3629_PE3 NOISO TQPQ-EEAQTPQAFSPFGNGLFP------YQQPPWQVPHRVP--PGYGRPPVSNEE-GGN RABIT15_81_PE10 NOISO TPAK-EETPPTQTFPPFNNGLFP------YQQPPWPFPQRMP-PPGYGR--LSNEE-GGN RAT14_PE303 NOISO ARAK-DEAQPPQPFPPFGNGLYP------YQQPPWPIPQTGP-PTGFGRPKFSNEE--GN SORARGS_2951_PE1 NOISO SKPK-EELPQHQAYPPFGYPF----------PPLWPIPHRMP--PGFGRPPSSNEE-GGN SPETR123914_PE1 NOISO ---------------------------------------RVP-PPRYGRLPLSNEE--GN TARSYGS_3427_PE1 NOISO PEPK-EETQPPQAFPPFNNGLFP------YQQPPWQIPQRMP-PPGYGRPPVSNEE-GGN TUPGBGS_5264_PE3 NOISO TEPK-EEAQPPQVFPPFNSGLFP------YQQPPWQIPQXXX-XXXXXXXXXXXXX-XXN TURTRGS_3203_1_PE1 NOISO TQPQ-EETQTPQAFPPFGNGLFP------YQQLPWHVPHRVP--PGYGRPPVSNEE-GGN MATCH CONSENSUS ??????????????PPF?NG?FP?????????PPW??P?R?P??PG?GRPP?SNEE?GGN

AILMEGL192678_1_1_PE11 NOISO PYFG-YFGYQGFGGRPPYYSEEMFEQDFEKPKE-EDPPKKESP-----AAEPSGNSTGPE BOVIN6_91_PE10 NOISO PFFG-FFGYHGFGGRPPYYSEEMFE-DFEKPKE-EDPPKTETP-----ATDPSVNSTVPE CALJA3_131_PE14 ENSCJAG00000014627 PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKAESP-----GTEPTANST--- CANFA13_64_PE23 NOISO PYFG-YFGYQGFGGRPPYYSEEMFEQDFEKPKE-KDPPKAESP-----AAEPSGNSTGPE CAVPO47_4_PE5 NOISO PYFG-FFGYPGFGGR-PYYSEEMFE-DYEKPKE-EDPPKPEDP-----PSEPSANSTVPE DASNO2495_PE3 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQNFEKPKE-KDPPKTESP-----AAEPTTNSTVPA DIPORGS_2762_PE1 NOISO PYFG-FFGYHGFGGR-PYYSEEMFD-DYEKPKE-KDPPKEESP-----ATETSANSTLTE ERIEUGS_3624_PE1 NOISO PYFG-YFGFHGFGGRPPYYSEEMFEQDFEKPKE-KDPPKTESP-----ATEPSPNSTTPE GORGO4_82_PE22 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKAESP-----GTEPTANSTVTE HORSE3_67_PE10 NOISO PYFG-YFGYHGFGGRPPYYSEEMFE-DFEKPKE-EDPPKAESP-----ATEPSSNSTVPE HS4_PE1449 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKAESP-----GTEPTANSTVTE LAMPAGS_3260_1_PE3 NOISO PFFG-YFGFHGFGGR-PYYSEEMFE-DFEKPKE-EDPPKTESP-----ATEPSTNSTVPE LOXAF30_28_PE11 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-KDPPKAESP-----ATEPTVNSTAPE MACMU5_61_PE10 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKAESP-----GTEPTANSTVTE MICMUGS_4254_PE3 NOISO XXXXXXXXXNAFGGCPPFFPEEIFGQGPGKPEGRGDPPKGEGP-----GPKPRPTSTVPG MONDO5_19_PE8 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKVEST-----TAAPPTNSTVPE MOUSE5_PE1333 NOISO PYYA-FFGYHGFGGR-PYYSEEMFE-DYEKPKE-KDPPKPEDPPPDDPPPEASTNSTVPD MYOLUGS_5518_PE3 NOISO PYFG-YFGYQGFGGRPPYYSEEMFEQDFEKPKE-KDPPKTESP-----ATEPSSNSTVPE OCHPR4304_PE3 NOISO PYFG-YFGYHGFGGRPPYYSEEMYD-DIEKPKE-EDPPKAESP-----STEPSANATVNE ORNANULTRA362_3_PE5 ENSOANG00000013692 PYFG-YFGHQGFGGRPPYYSEEMKEEEKESPKE-------DSP-----SPEPTANSTVAE OTOGAGS_5066_PE4 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKAESP-----GTEPTANTTATG PANTR4_62_PE8 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKAESP-----GTEPTANSTVTE PIG8_59_PE8 ENSSSCG00000008938 PYFG-FFGYHGFGGRPPYYSEEMFEQDFEKPKE-KDPPKTETP-----ATEPSVNTTVPE PONPY4_76_PE4 NOISO PYFG-YFGYHGFGGRAPYYSEEMFEQDFEKPKE-EDPPKAESP-----GTEPTANSTVTE PROCA5980_PE1 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-KDPPKTESP-----ATDPTPNTTVPE PTEVAGS_3629_PE3 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKEEEDPPKTEKP-----ATEPSSNSTVSE RABIT15_81_PE10 NOISO PYFG-FFGYHGFGGRPPYYSEEMYD-DIEKPKE-EDPPKAESP-----ATETSANATVNE RAT14_PE303 NOISO PYYA-YFGYHGFGGR-PYYSEEMFE-DYEKPKE-KDPPKPEDPPPDDPPPEASTNSTVPD SORARGS_2951_PE1 NOISO PYFG-FFGFHGFGGR-PYYSEEMFE-DYEKPKE-KDPPKAESP-----ATEPTSNSTVPE SPETR123914_PE1 NOISO PYFG-YFGYHGFGGHPPYYSEEMFD-DIEKPKE-KDPPKAESP-----PAEPSANSTVTE TARSYGS_3427_PE1 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-EDPPKKESP-----GTEPTANSTVTE TUPGBGS_5264_PE3 NOISO PYFG-YFGYHGFGGRPPYYSEEMFEQDFEKPKE-KDPPKAESP-----ATEPTANSTVTE TURTRGS_3203_1_PE1 NOISO YYLE-------HDGRPPLYSEEMQ--DFEKEKDPKE-----SP-----ATDHG-NSTVE- MATCH ..* * :.**: . : . . .:* CONSENSUS PYFG??FGY?GFGGR?PYYSEEMFE?D?EKPKE??DPPK?E?P???????EP??NST???

AILMEGL192678_1_1_PE11 NOISO -TNSTQSNAPNPGGSQGGNDTSPT---GP----------NMAQNGVNSPPTINVSGQGVP BOVIN6_91_PE10 NOISO -TNSTQPGAPSPRAGQGGNDTSPA---GNNGQDPNTVSNPTVQN----NPVVNVSGQGVP CALJA3_131_PE14 ENSCJAG00000014627 -TNSTQP---NPRGSQGGNDTSPT---VNSTPGPNTGNNPPGQNGIGPVPAVNASGQRGP CANFA13_64_PE23 NOISO -TNSTQS---NPGGSQSGNDTSPT---GNSGPGPNTVSNPTAQNGVISPATVNISGQGVP CAVPO47_4_PE5 NOISO -TNSTQL------TNQGKNDTGPT---LNSIPGLNTGNNPTVQNGIFPLPTVNFSGQVIP DASNO2495_PE3 NOISO -TNSSQPNTPGTGGSQGGNGTSPT---GNSAHVPNPGNNPTAQNVATPSPPIYVSGQEMP DIPORGS_2762_PE1 NOISO -TNSTQP---NAGGNQGGNDTNTT---GNSAPGQNPGSNPTPQNRVFPLPRVNVSGQAVT ERIEUGS_3624_PE1 NOISO -TNSTQPNAPNPRGNQPGNDTIQL---GNGGPGSNTVNNPAVQN---PSSTVNISGQGIP GORGO4_82_PE22 NOISO -TNSTQP---NPKGSQGGNDTSPT---GNSTPGLNTGNNPPVQNGIGPLPAVNASGQGGP HORSE3_67_PE10 NOISO -NNSTQPNAPNPRGSQGGNDTSPT---GNSGYGPNTVSNRTVQNGVILPPTVNISGQGIP HS4_PE1449 NOISO -TNSTQP---NPKGSQGGNDTSPT---GNSTPGLNTGNNPPAQNGIGPLPAVNASGQGGP LAMPAGS_3260_1_PE3 NOISO -TNSTQPNAPNPRGSQSGNDTSPS---GNSGQGPNTVSNPTAQNG----PVVNVSGQGVP LOXAF30_28_PE11 NOISO -TNSTQANVPGPGGSKGGNDTTPT---GNS-QGPNPGNNPTAQNGI-SPPTVNVSNQGVA MACMU5_61_PE10 NOISO -TNSTQS---NPKGSQGGNDTSPT---GNSIPGPNTGNNPPAQNGIVPLPAVNTSGQGGP MICMUGS_4254_PE3 NOISO GLTSPQP---SPKGGRGANGPTPP---GAGGP-------RARGAGGGPQPAGNASGPAVP MONDO5_19_PE8 NOISO -TNSTQATVPVSGGSQGGNETSTT---GNEAEVQNP--------GINLAPAVNVSGQDGP MOUSE5_PE1333 NOISO -ANATQS---IPEG---GNDTSPI---GNTGPGPNAGNNPTVQNGVFPPPKVNVSGQGVP MYOLUGS_5518_PE3 NOISO -TNSTQPNAPNPGGRPGGNDTSPT---GNSGHGPNTGGNPTAQNGVNPHPAVNVSGQGPP OCHPR4304_PE3 NOISO -TNSTQP---------GGNDTSPT---GNGAPGQNTGGNPTAQNGVNPSPTVNISGQGAS ORNANULTRA362_3_PE5 ENSOANG00000013692 -TNSTQPSGPSQAGSQGGNATDPGQSAGNGSPAQTPGHGTVPDNGEPPGPLLNASDHGGA OTOGAGS_5066_PE4 NOISO -TNSTQP---SPRGSPGGNDTNPA---GNGGPGPSTGGSPATPNGVTPPPAVNASGQGVP PANTR4_62_PE8 NOISO -TNSTQP---NPKGSQGGNDTSPT---GNSTPGLNTGNNPPAQNGIGPLPAVNASGQGGP PIG8_59_PE8 ENSSSCG00000008938 -TNSTQPNAPH------GNDTSPT---GTSGQGPNPRSNPTQ-----NGPAVNVSGQGVP PONPY4_76_PE4 NOISO -TNSTQP---NPKGSQGGNDTSPT---GNSTPGLNTGNNPPAQNGIGPLPAVNASGQGGP PROCA5980_PE1 NOISO -TNSTQSNVPGSGGNHGGNDTTLT---GNS-HGPNLGSNPTAQNGVISPSTANVSNQGVP PTEVAGS_3629_PE3 NOISO -TNSTQPNAPSPGGNQGGNDTSPT---GNSAHGPNTVSGPTAQNGAIPPPAVNVSGQGAQ RABIT15_81_PE10 NOISO -TNSTQP---NAGGSQGGNDTSPV---GNGAPGQNTGSNPTAQNGVNPSPAVNTSGQGAP RAT14_PE303 NOISO -ANATQS---IPGGGQGGNDSSPV---GNTGPGPNAGNNPTVLNGVFPLPKVNVSGQGVP SORARGS_2951_PE1 NOISO -SNSTQPNAASPR-----NDTITT---GNPAN--------NPQSGIIPSPTVNISGQGVS SPETR123914_PE1 NOISO -TNSTQP---NPGRSQGGNETFSI---GNNAPVPNTGSNPTAQNGVFPPPSVNVSGQGGP TARSYGS_3427_PE1 NOISO -TNSTQP---NTRGSQAGNDTSPT---GN------AGSNPTVQNGVIPPPTVNASGQGVP TUPGBGS_5264_PE3 NOISO -TNSTQP---NPGGSQGGNDTSPR----NSGPGPNTGSNPTAQNGGITPPPVNTSRQGVL TURTRGS_3203_1_PE1 NOISO -----TNTQSNPRGSQGGNDTSPT---GNSVQGSNTVSNPTAQN----SPAVNVSGQGVP MATCH * . . * CONSENSUS ?TNSTQ???????G???GNDT?P????GN?????N????P??QNG????P?VN?SGQG??

AILMEGL192678_1_1_PE11 NOISO RTQITWG--PSQPNIHENYPNPN-NRNFPVGRQWR------------PTGTIMGHRQNGP BOVIN6_91_PE10 NOISO RSQTPWR--PSQTNIHENYPYPN-IRNFPAGRQWH------------PTGTSMGNRRNGP CALJA3_131_PE14 ENSCJAG00000014627 GSQIPWR--PSQPNIRVNHPNPN-IRSFPSGRQWY------------PT--TMGHRQNGP CANFA13_64_PE23 NOISO RTQISWG--PNQPNIHENYPNPN-IRNFPAGRQWR------------PTGTFMGHRQNGP CAVPO47_4_PE5 NOISO GSQIPWK--PNQPNIYGSYPKPN-IRNSPSGRQSN------------PTHTATGQRPPGP DASNO2495_PE3 NOISO RSQIPWR--PSQSNIHEKYPNPN-IRDFPARRPWH------------PSGNVMGHRENGP DIPORGS_2762_PE1 NOISO RNQIPWR--SGQPNIYKNYPNPN-IRNFPSGKQWH------------PTGTVTDHRQFGP ERIEUGS_3624_PE1 NOISO RSQIPLG--RRQPNFHGNYPNPN-IRNYPAGRQWR------------PTGTILGHRQNWP GORGO4_82_PE22 NOISO GSQIPWR--PSQPNIHENHPYPN-IRNFPSGTQWY------------FTGTVMGHRQNRP HORSE3_67_PE10 NOISO RRQIPWR--PSQPKIHENYPNPN-IRNFPARRQWR------------PTGTATGNRQNGP HS4_PE1449 NOISO GSQIPWR--PSQPNIRENHPYPN-IRNFPSGRQWY------------FTGTVMGHRQNRP LAMPAGS_3260_1_PE3 NOISO RSQTPWG--PSQTNFHENYPNPN-IRSFPARRQWR------------PTGTAMGHRQNL- LOXAF30_28_PE11 NOISO RSQIPWR--QSHPNIHENYPHPS-VRGFPTGRQWR------------PTGTAMGHRQNGP MACMU5_61_PE10 NOISO GSQIPWR--PSQPNIRENHPNPN-IRNFPSGRRWY------------PTGTAMGHRQNGP MICMUGS_4254_PE3 NOISO GAQTPRR--PSQPTLRESYPSPN-ARNVPWVRQWY------------PAGTAVGRRQNGP MONDO5_19_PE8 NOISO GSQVPPG--PYQPTILENSPNPN-LRGFPISRQWS------------QTSFPVGPRLMGP MOUSE5_PE1333 NOISO KSQIPWR--PSQPNIYENYPYPN----YPSERQWQ------------TTGT-QGPRQNGP MYOLUGS_5518_PE3 NOISO RSQIPWG--SGQPNIRENYPNPN-FPSFPVGRQWR------------PTGTTVGHRQNGP OCHPR4304_PE3 NOISO RSQFPWR--PSQPNIYENYPNHN-TRNFPSGRQWH------------QTGTAVGQRPNGP ORNANULTRA362_3_PE5 ENSOANG00000013692 RGPKPTGPGPGQPPFRGRPANPNAAPGFPAGRQRRPFVHPFGRPFDRPVGRPVGRRDHGP OTOGAGS_5066_PE4 NOISO GSQSPWR--PSQPNIRENYPNPN-VRRFPSGRQWY------------PTGTAMGHRQTGP PANTR4_62_PE8 NOISO GSQIPWR--PSQPNIRENHPYPN-VRNFPSGRQWY------------FTGTVMGHRQNRP PIG8_59_PE8 ENSSSCG00000008938 RSQSPWG--PRQTIIHENYPNPN-IRGFPARRQWR------------PPGPAMGHRRNGP PONPY4_76_PE4 NOISO GSQIPWR--PSQPNIHENRPNPN-IRKFPSGRQWY------------LTGTVTGHRRNGP PROCA5980_PE1 NOISO RSQNPWG--PSYPNIHENYPYPG-AQGSPIARQWR------------PIGTAMGHRQNGP PTEVAGS_3629_PE3 NOISO RSQIPWG--PSQPNIRENYPNPN-LQSFPVGRQWR------------PTGTAMGHGQNGP RABIT15_81_PE10 NOISO RSQFPWR--PSQPNIYENYPNHN-TRNFPSERQWH------------HTGTAVGHRPNGP RAT14_PE303 NOISO KNQIPWR--PSQPNIYENYPYPN----YPSERQWQ------------TTDT-QGPKQNGP SORARGS_2951_PE1 NOISO RNQIPLG--PRH-NFYENYPNPN-VRNVPAGRQWR------------PTGTDTWQRQNVP SPETR123914_PE1 NOISO RSQIPWK--PSQPKIHEIYPNPN-IRNPPTGRQWH------------PTGTAMGHRQYGP TARSYGS_3427_PE1 NOISO GSQIPWR--PSQPNIRENYPNPN-VRRFPSGRPWY------------PTGTVTGHRQNGP TUPGBGS_5264_PE3 NOISO GNQIPWR--PSQPNI---HPNPN-IRNFPSGRQWH------------STGTAMGNRQTRP TURTRGS_3203_1_PE1 NOISO RSQTPQG--PSQTNIHENYPNPN-IRSFPAGRQWR------------PTGTATGHKRNGP MATCH . : . . * CONSENSUS ??Q?PW???P?QPNI?EN?P?PN??R??P??RQW??????????????TGT??G?R???P

AILMEGL192678_1_1_PE11 NOISO FYRNQQFQRGP-RWNSFALERKQA-VRPGNPIYRKAYASTAR-GNSPNHAGNLGNFRRKP BOVIN6_91_PE10 NOISO FYRNQQIQRAP-RWNSFVLEGKQA-IRLGYPIYRRAYASTVR-GNYPNYAGNPVNFRRKP CALJA3_131_PE14 ENSCJAG00000014627 FYRNRQVQRGL-RWNSFPWEGKQV-ARPRNPVYHIAYPSTSR-GNYPNYAGNPANLRRKP CANFA13_64_PE23 NOISO FYRNQQVQRGP-RWNSFALERKQA-MRPGNPIYRKAYASTAR-GNSPNHAGNLGNVRRKP CAVPO47_4_PE5 NOISO SYRNQPGQWDA-QGNSFAWEGKQA-AGPKNPTYHKAYTPTSR-KNYPSYAGNPANFRRKL DASNO2495_PE3 NOISO FYRN-QVQRGP-RWNSFALESKKA-VLLGNPAYHKVCPSISR-GSLPKHAGNPANFRRKP DIPORGS_2762_PE1 NOISO FYRNQQGQRGP-QWNSFAWEGKQA-ARPGNPIYRKSYPPTSR-VNYPNYVGNPANFKRKP ERIEUGS_3624_PE1 NOISO FYRTQQVQGSP-RWHSFALENKQA-LRPGTPFYRKAYASTAR-GNSPNQAGNPANFKRKP GORGO4_82_PE22 NOISO FYRNQQVQRGP-RWNSFAWEGKQV-ARPGNPVYHKAYPPTSR-GNYPNYAGNPANLRRKP HORSE3_67_PE10 NOISO FYRN-QVQRDP-QWNSFAWEGKRT-VHPGNPIYRKSYTPTTR-GNSPNNAGNPANIRRKP HS4_PE1449 NOISO FYRNQQVQRGP-RWNFFAWERKQV-ARPGNPVYHKAYPPTSR-GNYPNYAGNPANLRRKP LAMPAGS_3260_1_PE3 NOISO -YESQQ---RG-LW-SFALRKQAH-----EYPYRKAMLS----SNAFNYA-GPVNFRRK- LOXAF30_28_PE11 NOISO FYRNQQVQRGA-RWNSFTLEGKQA-ARPGNPAYRKAYPSISR-GNYLNHAGNPANFRRKP MACMU5_61_PE10 NOISO FYRNRQVQRGP-QWNSFAWEGKQV-VRPGNPVYHKVYPSISR-GNYPNYAGNPANLRRKP MICMUGS_4254_PE3 NOISO LYRSQQFQRVP-RWHSFALESKQV-ARPVNPPYRRAYPSTSG-GHYPNYAGNPANLRRKP MONDO5_19_PE8 NOISO FYRNYPNQRSY-QWPSLAYVSKQI-VRPGNTAYQKVYPYISK-SNSPNHVSNPANNRRKP MOUSE5_PE1333 NOISO GYRNPQVERGP-QWNSFAWEGKQA-TRPGNPTYGKPPSPTSG-VN---YAGNPVHFGRNL MYOLUGS_5518_PE3 NOISO FYRN-PVQRGP-RWNSYAWEGKQA-VRPGNPIYHRPYASTAR-GNSPNLAGNPANFRRKP OCHPR4304_PE3 NOISO FYRNQQVQKNS-QWNSFAWENKQA-TNPGNPASHKTFLSTSR-GYYTNNAGNPVNFRKRP ORNANULTRA362_3_PE5 ENSOANG00000013692 TYGNTPKARGPLRWNAVTSEGKRV-ARPGYPMYRRPFPVAAPGRGFPNRAGNPLNLRKNP OTOGAGS_5066_PE4 NOISO FYRNQQFQRGP-RWNSFV----QV-ARAGNPTYHKAYPSTSR-GNYPNYSGNPANLRRKP PANTR4_62_PE8 NOISO FYRNQQVQRGP-RWNSFAWEGKQV-ARPGNPVYHKAYPPTSR-GNYPNYAGNPANLRRKP PIG8_59_PE8 ENSSSCG00000008938 FYRNQQIQRGP-RWNSFTLEGKQA-VRPGYPTYRRVYGSTAR-SNPPNYAGNSANLRRKP PONPY4_76_PE4 NOISO FYRNQQVQRGP-RWNFFAWEGKQV-ARPGNPVYHKAYPSTSR-GNYPNYAGNPANLRRKP PROCA5980_PE1 NOISO LYRNQQVQRGP-RWNSFTLEGKPA-ARPGNPAYQKAYPSISR-GNSLNYARNPANFRRKP PTEVAGS_3629_PE3 NOISO FYRNQQVQRGP-RWNSFALEDRQT-VRPGNPIYRKPYASTAR-GNSPSHAGNPANFRRKP RABIT15_81_PE10 NOISO FYRNQQVQRGT-QWNSFAWESKQA-TRPENPTYRKTFHSTTR-GYYTNYAGNPANFRRRP RAT14_PE303 NOISO GYQNPQIQRGP-QWNSFAWEGKQATTHPGNPTYHKPSPPTSR-VNYPNYAGNPVNFGRKL SORARGS_2951_PE1 NOISO FYRNQLYQRGP-RWNSFTLENKQA-IRPGIPFYSKAYASTAR-GNSPNQAGNPTNFKRKP SPETR123914_PE1 NOISO LYRNQQVQRGP-RWNSLAWEGKQA-TRPGNPTYRKAYPPTSR-VNYPNYAGNPANFRRKP TARSYGS_3427_PE1 NOISO FYRTQQVQRGP-RWNSYAWENKQA-ARPGNPTYHRAYPSTSR-GNYPNYARNLAHSRRKP TUPGBGS_5264_PE3 NOISO FYRNQQVQRGP-SWNSFALESKQA-AHPRTPTYRKAYSSISR-GNYANYAGNPANLRRKP TURTRGS_3203_1_PE1 NOISO FYRNQQIQRGP-RWNSFVLEGKQA-VRPGYPIYRRAYASTAR-GNSPNYAGNPANFRRKP MATCH * . . : :. CONSENSUS ?YRN?Q?QR????WNSF??E?KQ????PG?P?Y????????R??N??N?AGNP?N?RRKP

AILMEGL192678_1_1_PE11 NOISO QGPNK------------------------------------------------------- BOVIN6_91_PE10 NOISO EGPSK------------------------------------------------------- CALJA3_131_PE14 ENSCJAG00000014627 QGPNK------------------------------------------------------- CANFA13_64_PE23 NOISO QAPNK------------------------------------------------------- CAVPO47_4_PE5 NOISO QGPNK------------------------------------------------------- DASNO2495_PE3 NOISO QGLNK------------------------------------------------------- DIPORGS_2762_PE1 NOISO QGPNK------------------------------------------------------- ERIEUGS_3624_PE1 NOISO QTPNK------------------------------------------------------- GORGO4_82_PE22 NOISO QGPNK------------------------------------------------------- HORSE3_67_PE10 NOISO QGPNK------------------------------------------------------- HS4_PE1449 NOISO QGPNK------------------------------------------------------- LAMPAGS_3260_1_PE3 NOISO QGPNK------------------------------------------------------- LOXAF30_28_PE11 NOISO QWPNK------------------------------------------------------- MACMU5_61_PE10 NOISO QGPNK------------------------------------------------------- MICMUGS_4254_PE3 NOISO QEPNK------------------------------------------------------- MONDO5_19_PE8 NOISO QGPTK------------------------------------------------------- MOUSE5_PE1333 NOISO PGPNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNK MYOLUGS_5518_PE3 NOISO QGPNK------------------------------------------------------- OCHPR4304_PE3 NOISO QGPNK------------------------------------------------------- ORNANULTRA362_3_PE5 ENSOANG00000013692 QAPAKHP----------------------------------------------------- OTOGAGS_5066_PE4 NOISO QELNK------------------------------------------------------- PANTR4_62_PE8 NOISO QGPNK------------------------------------------------------- PIG8_59_PE8 ENSSSCG00000008938 EGPNK------------------------------------------------------- PONPY4_76_PE4 NOISO QGPNK------------------------------------------------------- PROCA5980_PE1 NOISO QLPNK------------------------------------------------------- PTEVAGS_3629_PE3 NOISO QRPQK------------------------------------------------------- RABIT15_81_PE10 NOISO QGPNK------------------------------------------------------- RAT14_PE303 NOISO PGPKKPFMGANPASNKPFVGANPASNKPFVGTNPASNKPFVGANPASNKPFVGANPASNK SORARGS_2951_PE1 NOISO QNPNK------------------------------------------------------- SPETR123914_PE1 NOISO QAPNK------------------------------------------------------- TARSYGS_3427_PE1 NOISO QGPNK------------------------------------------------------- TUPGBGS_5264_PE3 NOISO QGPNK------------------------------------------------------- TURTRGS_3203_1_PE1 NOISO EGPNK------------------------------------------------------- MATCH * CONSENSUS Q?PNK???????????????????????????????????????????????????????

AILMEGL192678_1_1_PE11 NOISO ------------------------------------------------------------ BOVIN6_91_PE10 NOISO ------------------------------------------------------------ CALJA3_131_PE14 ENSCJAG00000014627 ------------------------------------------------------------ CANFA13_64_PE23 NOISO ------------------------------------------------------------ CAVPO47_4_PE5 NOISO ------------------------------------------------------------ DASNO2495_PE3 NOISO ------------------------------------------------------------ DIPORGS_2762_PE1 NOISO ------------------------------------------------------------ ERIEUGS_3624_PE1 NOISO ------------------------------------------------------------ GORGO4_82_PE22 NOISO ------------------------------------------------------------ HORSE3_67_PE10 NOISO ------------------------------------------------------------ HS4_PE1449 NOISO ------------------------------------------------------------ LAMPAGS_3260_1_PE3 NOISO ------------------------------------------------------------ LOXAF30_28_PE11 NOISO ------------------------------------------------------------ MACMU5_61_PE10 NOISO ------------------------------------------------------------ MICMUGS_4254_PE3 NOISO ------------------------------------------------------------ MONDO5_19_PE8 NOISO ------------------------------------------------------------ MOUSE5_PE1333 NOISO PYVGANPASNKPFIGANPAANKPSIGTNPAANKPSIGTNPAANKPFVRNNVGAN------ MYOLUGS_5518_PE3 NOISO ------------------------------------------------------------ OCHPR4304_PE3 NOISO ------------------------------------------------------------ ORNANULTRA362_3_PE5 ENSOANG00000013692 ------------------------------------------------------------ OTOGAGS_5066_PE4 NOISO ------------------------------------------------------------ PANTR4_62_PE8 NOISO ------------------------------------------------------------ PIG8_59_PE8 ENSSSCG00000008938 ------------------------------------------------------------ PONPY4_76_PE4 NOISO ------------------------------------------------------------ PROCA5980_PE1 NOISO ------------------------------------------------------------ PTEVAGS_3629_PE3 NOISO ------------------------------------------------------------ RABIT15_81_PE10 NOISO ------------------------------------------------------------ RAT14_PE303 NOISO PFVGANPASNKPFVGANPASNKPFMGTNPAANKPSIGTNAASNKPFVGTNAGTNKPFMGI SORARGS_2951_PE1 NOISO ------------------------------------------------------------ SPETR123914_PE1 NOISO ------------------------------------------------------------ TARSYGS_3427_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5264_PE3 NOISO ------------------------------------------------------------ TURTRGS_3203_1_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192678_1_1_PE11 NOISO --------------------------------------------------HPMGTNV--- BOVIN6_91_PE10 NOISO --------------------------------------------------QPEGT-I--- CALJA3_131_PE14 ENSCJAG00000014627 --------------------------------------------------HPVRTNV--- CANFA13_64_PE23 NOISO --------------------------------------------------HPMGTNV--- CAVPO47_4_PE5 NOISO --------------------------------------------------PFVGTNV--- DASNO2495_PE3 NOISO --------------------------------------------------HTVGTNV--- DIPORGS_2762_PE1 NOISO --------------------------------------------------QPVGTNA--- ERIEUGS_3624_PE1 NOISO --------------------------------------------------QPIGTSV--- GORGO4_82_PE22 NOISO --------------------------------------------------HPVGTTV--- HORSE3_67_PE10 NOISO --------------------------------------------------PPVVTN---- HS4_PE1449 NOISO --------------------------------------------------HPVGTTV--- LAMPAGS_3260_1_PE3 NOISO --------------------------------------------------YM-G-NN--- LOXAF30_28_PE11 NOISO --------------------------------------------------YPVGANV--- MACMU5_61_PE10 NOISO --------------------------------------------------HPMGTNV--- MICMUGS_4254_PE3 NOISO --------------------------------------------------HPVGTNV--- MONDO5_19_PE8 NOISO --------------------------------------------------QPEEING--- MOUSE5_PE1333 NOISO ----------------KPFVGTNPSSNQPFLRSNQASNKPFMRSNQASNKPFVGTNV--- MYOLUGS_5518_PE3 NOISO --------------------------------------------------HPMGTNV--- OCHPR4304_PE3 NOISO --------------------------------------------------NVVVTNV--- ORNANULTRA362_3_PE5 ENSOANG00000013692 ----------------------------------------------------GEANS--G OTOGAGS_5066_PE4 NOISO --------------------------------------------------HPLGAST--- PANTR4_62_PE8 NOISO --------------------------------------------------HPVGTTV--- PIG8_59_PE8 ENSSSCG00000008938 --------------------------------------------------NPMVTNV--- PONPY4_76_PE4 NOISO --------------------------------------------------QPVGTNV--- PROCA5980_PE1 NOISO --------------------------------------------------YPTGANA--- PTEVAGS_3629_PE3 NOISO --------------------------------------------------HLMGTNI--- RABIT15_81_PE10 NOISO --------------------------------------------------NVIGTNV--- RAT14_PE303 NOISO NVASNKPFMGTNPASNKPFVGTNPASNKPFVRSNHASNKPFVGANAASNKPFVGTNV--- SORARGS_2951_PE1 NOISO --------------------------------------------------QPLGPNTAQN SPETR123914_PE1 NOISO --------------------------------------------------HLMGTNV--- TARSYGS_3427_PE1 NOISO --------------------------------------------------HPMGTSA--- TUPGBGS_5264_PE3 NOISO --------------------------------------------------HPMGTNV--- TURTRGS_3203_1_PE1 NOISO --------------------------------------------------HPVGTNV--- MATCH CONSENSUS ?????????????????????????????????????????????????????G??????

AILMEGL192678_1_1_PE11 NOISO APLGPKQGTVVHNEKIQNPAEKPVGPKERIVIPTRDPSGPWRNSQDY-GVNKSNYKLP-- BOVIN6_91_PE10 NOISO APLGPKHGTTGHNENIQNPKEKPVSQKERIVIPTRDPNGPWRNSQDY-GVTKSNYKLP-- CALJA3_131_PE14 ENSCJAG00000014627 APLGPKHDPVVQNEKIQNPREKPLSPKEQIIVPTKTPTSPWRNSQQY-EVNKSNYKLP-- CANFA13_64_PE23 NOISO APLGPKHGTVVHNEKIQNPGEKPVGPKERIVIPTRDPSGPWRNSQDY-GVNKSNYKLS-- CAVPO47_4_PE5 NOISO TPMSPKQGTIGRNEKIQNPKEKSLGQKESTINPTKGMSGSWRNSQYP-GVNKPNYGWP-- DASNO2495_PE3 NOISO ALLGPSHGTVGHSEKFQNPRENSVSQKETIGSPTRDPTDPWRNSHDN-GANKSNYKLP-- DIPORGS_2762_PE1 NOISO ASLGPKQGIVGRNEKIQNPKSPGPQ-----TPSTQATPAPWRNSQHY-RINKPNYKVP-- ERIEUGS_3624_PE1 NOISO APVAPKRDPVGHNEKIQNPRENSLGQKERIVIPTRDPTGPWRNSQDY-GINKSNFKPS-- GORGO4_82_PE22 NOISO APLGPKPGPVVRNEKIQNPREKPLGPKEQIIVPTKNPTSPWRNSQQY-EVNKSNYKLP-- HORSE3_67_PE10 NOISO VPLGPKHDTVDLNEKVQNPREKPPDQK-EIVIPTRDPPGPWRNSEDY-GINKPNYKLP-- HS4_PE1449 NOISO APLGPKPGPVVRNEKIQNPKEKPLGPKEQIIVPTKNPTSPWRNSQQY-EVNKSNYKLP-- LAMPAGS_3260_1_PE3 NOISO VALDPKHGTVGGNENIQNPRENPVSQKERTVTPTMDPNGPWRNSQDY-GVNKSNYKLP-- LOXAF30_28_PE11 NOISO APLGTKHSTAGRSEKIQNPREKTLGQKERVVVPTRDPPGPWKNSQDY-GLNKSNYKLP-- MACMU5_61_PE10 NOISO APVGPKHGPVVHNEKIQNPREKHLGPKEQIIVPTKNPTSPGRNSQQY-EVNKSNYKLP-- MICMUGS_4254_PE3 NOISO ATLGPKHSTVNRNEKVQNPREKPLGQKQRVAVPTKEPSGPWRNSQHY-GVNKSNYKLP-- MONDO5_19_PE8 NOISO GLAGPKLGTAHKEEQIQNPKENSVTQRERITFPTRDPTSTWRNSQGY-ETNKSNYKLT-- MOUSE5_PE1333 NOISO ASVGPKQVTVSHNMKTQNPKEKSLGQKERTVTPTKDASNPWRSAKQY-GINNPNYNLP-- MYOLUGS_5518_PE3 NOISO APLGPKHGTVGRNEKIQNPREKPLGQKERVVIPTRDPTGPWRNSQDN-EANKSNYKLP-- OCHPR4304_PE3 NOISO VPLDPNQGTVGYSEKVQNPGEKQVGQKERTVVPTKDTVSLWRNSHPYGGVNKPNYKLP-- ORNANULTRA362_3_PE5 ENSOANG00000013692 PVYSQRGGLMAPREPVASPQENPPSPREKPSFPTRGPAVPWRKPQNY-GPGKPVYRPP-- OTOGAGS_5066_PE4 NOISO APLGPKPSTVSPSEKVQNPKEKPLGQKERIVVPTKDPTGPWRKSQQY-GVNKSNYKLP-- PANTR4_62_PE8 NOISO APLGPKPGPVVRNEKIQNPREKPLGPKEQIIVPTKNPTSPWRNSQQY-EVNKSNYKLP-- PIG8_59_PE8 ENSSSCG00000008938 APPGPKHGTVDQNENIQNPREKQVSQKERTVIPTRDPSGPWRNSQDY-GINKSNYKLP-- PONPY4_76_PE4 NOISO APLGPKHGPVVRNEKIQNPGEKPLGPKEQIIVPTKNPTSPWRNSQQY-EVNKSNYKLP-- PROCA5980_PE1 NOISO APLGTKQGTVGRNEKIQSPGEKSPAQKERIVVPTREPTGLRKNSQDF-GVSKPNYKLP-- PTEVAGS_3629_PE3 NOISO VPLGSKHGTVSPSEKIQNPREKPLGQKERIVIPTRDPTGPWRNSQDY-EVNKLNYKLP-- RABIT15_81_PE10 NOISO ASLGPKQGSVGHNEKVQNPKEKSIGQKERTVVPTKDTTGPWKNSQSY-GVNKRYYKLP-- RAT14_PE303 NOISO PSVGPKQVTVSHNMKTQNPKEKSLGQKERTVTPTKDTGNPWRSSKQY-GINNPNYNLP-- SORARGS_2951_PE1 NOISO VPLGPKNDIAGRNEKTQNPKEKPVGQKERIVTPTRDPTGPWRNSQDL-GVNKSNYKPPNP SPETR123914_PE1 NOISO IPLGPKQATVGRNEKIQNPQEKSLGQKDRMISPTKDTAGVWKTSQHY-GVNKPNYKSP-- TARSYGS_3427_PE1 NOISO APLSPKPGTVDRNEKTQTPREKPLGQKERVVIPTKIPTGPWRNSQHY-EVNKSNYKPP-- TUPGBGS_5264_PE3 NOISO APLGPKHGTVGHNEKIQNPKEKSPGQKERIVVPTKAPTGPWRNTQNY-GVNKPNYKLP-- TURTRGS_3203_1_PE1 NOISO APLGPKHGTVGHNENIQNPREKPVSQKEGIVIPTRDPSGPWRNSQDY-GVNKSNYKLP-- MATCH .* . .* :... : : . CONSENSUS ???GPK???V???EK?QNP?EK????KE????PT?????PWRNSQ?Y???NK?NYK?P??

AILMEGL192678_1_1_PE11 NOISO HPESNMLVPNFNSIDQHENSYYPRGDS--RRAPNSDGQTQTQNLPKGIILEPRRNPYESE BOVIN6_91_PE10 NOISO HPEGNILVPNFNSIDQHENSYYPRGDS--RGTPNSNGQTQSQNLPKGIILEPRRIPYESE CALJA3_131_PE14 ENSCJAG00000014627 HSEGYTPVPNFNSVDQHENSYYPRGDS--RKVPNSDGQTQSQNLPKGIVLGPRRIPYESE CANFA13_64_PE23 NOISO PPESNVLVPNFNSVDQHENSYYSRGDS--RRAPNSDGQTQSQNLPKGIILEPRRNPYESE CAVPO47_4_PE5 NOISO HPEDNMLGPNFNSVNQYENSYYPRGEV--IKVPSSNAKTQSQNFPKRVALEPKRIPYESQ DASNO2495_PE3 NOISO DSEGNRPAPSFNSIDQQENSYYPRGDS--RRTSNSDGQTQSLHLPKGIVLEPRRIPHESE DIPORGS_2762_PE1 NOISO RPEGNMIGPNFNSVNQRENSYYPRGDS--KRAPSSKAQTQSHNLPKGIALEPKRIPYESE ERIEUGS_3624_PE1 NOISO RPEGNMPVPNFNSIDQHENSYYPRGDS--RRAPNSDGQAPSQNLPKGIVLEPKRIPYESE GORGO4_82_PE22 NOISO HSEGYMPVPNFNSVDQHENSYYPRGDS--RKVPNSDGQTQSQNLPKGIVLGSRRMPYESE HORSE3_67_PE10 NOISO HSEGNILVPNFNSVDQRENSYYPRGDI--IRAPNYDGQTQSQNLPKGIILEPRRIPYESE HS4_PE1449 NOISO HSEGYMPVPNFNSVDQHENSYYPRGDS--RKVPNSDGQTQSQNLPKGIVLGSRRMPYESE LAMPAGS_3260_1_PE3 NOISO HPEGNMLAPNFNSIDQ--NSYYPRGDS--KRAPNSEGQIQSQNLPKGIILEPRRIPYESE LOXAF30_28_PE11 NOISO HSEGNIQVPSFNSINQRENSYYPRGDP--RTVQNSDGQTHNKYLPKGIVLEPRRIPYESQ MACMU5_61_PE10 NOISO HSEGYTPVPNFNSVDQHENSYYPREDS--RKLPNSDGQTQSQILPKGMVLAPRRIPYESE MICMUGS_4254_PE3 NOISO PPESNMPVPSFNSVDQRENSYYQTGDS--TRIPNSNGQTQSQNLPKGIVLEPRRSPYESE MONDO5_19_PE8 NOISO PPQGSPSVPSVNSVDQPEN-YYPRVDS--RRFPAS---IQASNFPKGIVSEPRKGPSDSE MOUSE5_PE1333 NOISO RSEGSMVGPNFNSFDQQENSYFSKGAS--KRVPSPNIQIQSQNLPKGIALEPRRTPFQSE MYOLUGS_5518_PE3 NOISO PPEGNKQLPNFNSIDQRENSYYPRGDS--RRAPNSDGQAQSQNLPKGIILEPRRIPYESE OCHPR4304_PE3 NOISO RPIGNTPGPNFNSIGQQENPYSPTGDS--RRVPNSGVQIQSQNLPNGIILEPKITPYAPE ORNANULTRA362_3_PE5 ENSOANG00000013692 LSEGRPADPGPSPFDPRENPYYPRGDATDRRFLSSGGSAPGRHFPEGIVLKPED------ OTOGAGS_5066_PE4 NOISO HPERNTPVPNFNSIDQREN-YHQIGDS--TRLPNSNGQTQSQNLPKGIVLEPRRVPYESE PANTR4_62_PE8 NOISO HSEGYMPVPNFNSVDQHENSYYPRGDS--RKVPNSDGQTQSQNLPKGIVLGSRRMPYESE PIG8_59_PE8 ENSSSCG00000008938 QPEDNMLVPNFNSIDQRENSYYPRGES--KRAPNSDGQTQTQIIPKGIVLEPRRIPYESE PONPY4_76_PE4 NOISO HFEGYMPVPNFNSVDQYENSYYPRGDS--RKVPNSDGQTQSQNLPKGIVLGSRRMPYESE PROCA5980_PE1 NOISO GSEGNMQVPSFNTIDQHENSYYPREDS--RRVQNSDGQTPNQYLPKGVVLEPRRIPYESE PTEVAGS_3629_PE3 NOISO HPEGNRLIPNLNSIDQRENSYYPRGDS--RRAPNSDGQTQSQNLPKGIIVEPRRIPYESE RABIT15_81_PE10 NOISO WSEGNIQGPNFNSIGQQENSYNPRGDS--RRIPNSGVQIQSQNLPKGIVLQPKRTPYEPQ RAT14_PE303 NOISO HPEGSMVGPNFNSFDQQENTYFSRGDS--RKVASPNRQIQSQNLPKGIALEPRRTPFESE SORARGS_2951_PE1 NOISO HPSGNRLIPNFNSVDQRENPYYPRGDT--RRAPNSDGQTQSQNLPKGIALDPKRIPYEPE SPETR123914_PE1 NOISO RPEDNMLGPNFNSINQRENSYFPRGDS--RKAPSSDVQTQSQNLPKGIALEPRRIPYESE TARSYGS_3427_PE1 NOISO PPESNTRVPNFNSIDQRENSYYPREDS--RRIPNSDGPTQSQNLPKGIVLEPRRIPYGSE TUPGBGS_5264_PE3 NOISO HPEDNTEIPTFNSIDQHVNSYYPRGDS--KRVQNSDGQIQNQNLPKGIVLEPRRNPYESE TURTRGS_3203_1_PE1 NOISO HPEDNMLVPNFNSIGQRENSYYLRGDS--RRAPNSNGQTQSQNLLKGIILEPRRIPYESE MATCH * .... * * : : : .. CONSENSUS ??E?????P?FNS??Q?ENSYYPRGDS?????P?S??Q?Q?QNLPKGI?L?P?R?PYESE

AILMEGL192678_1_1_PE11 NOISO TNQPELKHSTYQPVYP-------EEIPSPAREHFPAGRNTWNHQEISPSFKEDPGRQEEH BOVIN6_91_PE10 NOISO INQPEIKHSTHQPVYP-------EGSPSPARERFPAGRNTWNQQEISPPFKEDPGRKEEH CALJA3_131_PE14 ENSCJAG00000014627 TNQPKLKHSSYQPVYLEEKPVYPEEIPSSAKEDFPARRNSWNHQEISPPFKEDPGRQEEH CANFA13_64_PE23 NOISO TNRPELKHSTYQPVFP-------EEIPPPAREHFPAGRNTWHHQEISPSFKEDPGRQEEL CAVPO47_4_PE5 NOISO TMQPELKHSTHQPIYP-------EVIPSPKREHFPAGRNTWSHHEIPPPFKEDPGKQDKH DASNO2495_PE3 NOISO TSWPELKHSTFHPVYP-------EEIPSSARENFPAGRNIWNHQEISPNFGKDPGRQDGH DIPORGS_2762_PE1 NOISO TKQHEPKHNTHQPVYP-------KEIPSPTREHFPAGRNTWNHQGIPPSFKEDPGRQEKH ERIEUGS_3624_PE1 NOISO TNGPELKQNTYPPVYL-------EEIPPPERELFPVGRNTWNHQEISPPFKEDPRRQEEH GORGO4_82_PE22 NOISO TNQPELKHSSYQPA------VYPEEIPSPAKEHFPAGRNTWDHQEISPPFKEDPGRQEEH HORSE3_67_PE10 NOISO TNQPELKHSTYQPVYP-------EETPSPAREHFPTERNTWNHQEISPHFKEDPGRQEEH HS4_PE1449 NOISO TNQSELKHSSYQPA------VYPEEIPSPAKEHFPAGRNTWDHQEISPPFKEDPGRQEEH LAMPAGS_3260_1_PE3 NOISO TKQPELTQNTYQPVYP-------EGIPSPARERFPTGRNTWNQQEISPPFKEDPGRQEEH LOXAF30_28_PE11 NOISO TNRPELKHGTYHPVYP-------EEIPSPAREHFPAGRNHWNNQELSPTLEEDPGRQEEP MACMU5_61_PE10 NOISO TNQPELKHSAYQPA------VHPEEIPS-AKEHFPAGRNTWDHQEISPPFKEHPGRQEEH MICMUGS_4254_PE3 NOISO TQQPELKHRTYQPGYP-------EEIPSPARGHFPAGKNTWNPQEISPPFKEDLGRQEEH MONDO5_19_PE8 NOISO INPPEIKHGTHQT----------DEGPYPPKESFFLRSNTWNLQKGSPIFEDEPTKQEGS MOUSE5_PE1333 NOISO TKKPELKHGTHQPAYP-------KKIPSPTRKHFPAERNTWNRQKILPPLKEDYGRQDEN MYOLUGS_5518_PE3 NOISO TNQPELKHSTYQPAYP-------EDIPSPAGERFPAGRNTWNHQDISPPFKEDPNRQEEH OCHPR4304_PE3 NOISO TSQPKLKYKTYQPVYP-------EGIPAPTREHPPAGRNTWNHQDISPPFKGNSRWQEEH ORNANULTRA362_3_PE5 ENSOANG00000013692 -DQPPSKQKPFHPVTSERTPR----EPSPTK-------PQRTSPEPPPPLEEGPGRQDKS OTOGAGS_5066_PE4 NOISO TNQPELKHSTYQPVY-------PEEIPSPAREHFPAGKNTWNHQEISPPFKEDPVRQEEH PANTR4_62_PE8 NOISO TNQPELKHSSYQPA------VYPEEIPSPAKEHFPAGRNTWDHQEISPPFKEDPGRQEEH PIG8_59_PE8 ENSSSCG00000008938 TNQPELKHSAYQPVYT-------EGIPSPAKEHFPAGRNTWNQQEISPPFKEDPGRQEEH PONPY4_76_PE4 NOISO TNQPELKHSSYQPA------VYPEEIPSPAKEHFPAGRNTWDHQEISPPFKEDPGRQEEH PROCA5980_PE1 NOISO TNGPELKHSTYHPVYP-------EEIPSPAREHFPAERKHWNQ-QISPTLEEDPGKQVRP PTEVAGS_3629_PE3 NOISO TNQPELKHSTHQSVYP-------EEIPSPAREHFPAGRNTWNRQEISPPFKEDPGRQEEH RABIT15_81_PE10 NOISO TNQPELKHRTYQPAYP-------KEIPTSTREHFPTGRNTWNHQEISPRFKEDPRWQAKR RAT14_PE303 NOISO TKRPELKHSTNMPVYP-------KKNPSPTRGHFPAGRNNWNHQKTLPPLKEGHGRKEEN SORARGS_2951_PE1 NOISO TNGPEIKANTYQPAYP-------AEIPSSAREQFPAGRNNWNHQEISPSFKDELGRQEGQ SPETR123914_PE1 NOISO TNQPELKHSTQQPVYP-------EEIPSTTREHFPTGRNTWSNKEIPPYFKEDPGRQEEH TARSYGS_3427_PE1 NOISO TNQPELKPSTYQPVYLE-------EIPSPAREHFPTGRNTWTHQETPPPFREDPRRREEH TUPGBGS_5264_PE3 NOISO TNRPELKHSTYQPAYPE-------EIP-PVKEHFPAGRNTWNHQEISPPFKEDPGRQ-EH TURTRGS_3203_1_PE1 NOISO INQPELKHSIYQPVYP-------EGFPSPAREHFNAGRNTWNQQEISPPFKEDPGRHEEH MATCH . . * * : : CONSENSUS T??PELKH???QP????????????IPSP??E?FP?GRN?W??Q?I?P?FKEDP?RQ???

AILMEGL192678_1_1_PE11 NOISO LP---HPSHGSRGGVYYPDSYYHNSYDPRENSPYPRSNTWDERD-DSPNTI---GQPKNS BOVIN6_91_PE10 NOISO LP---HPSLGSRGRIYYTD---YNPYDRRENPPYLRSNSWDERN-DPPNTM---GQSENP CALJA3_131_PE14 ENSCJAG00000014627 LP---HSSHGSRGSVFYPE---YNPYDPRENSPYRRSNTWDERE-DSPNTM---GEKESP CANFA13_64_PE23 NOISO LP---PPSQGSRGGVYYPDY---NSYDPRENSPYLRSNRWDERD-DSPNTI---GQPRNS CAVPO47_4_PE5 NOISO LP---HVSPGSQDSVFYHK---YNSFYTRENSPYTGSNTWEKRA-DSPKT-----QAKTP DASNO2495_PE3 NOISO LP---QSSHGSRGSVFYPE---YNPYDPRENSPYLRGNTWDE-D-DSPNTM---GQPEHP DIPORGS_2762_PE1 NOISO LP---HLSHGSNRNVFYPN---YSPYYPRENSLYIGGNIWDERVDDTPKTV---RQPENS ERIEUGS_3624_PE1 NOISO LP---RPSQGSRGGVYYPD---YNPYTPRENVPYQRSNTWDERD-DSPNTV---RQAENP GORGO4_82_PE22 NOISO LP---HPSHGSRGSVFYPE---YNPYDPRENSPYLRGNTWDERD-DSPNTM---GQKESP HORSE3_67_PE10 NOISO LP---HPSLGSRGGVYYPD---YYPYDPRENSPYFRGNAWDERN-YSPNTM---GRLKNP HS4_PE1449 NOISO LP---HPSHGSRGSVFYPE---YNPYDPRENSPYLRGNTWDERD-DSPNTM---GQKESP LAMPAGS_3260_1_PE3 NOISO LS---HPSHGSRGRVYYPD---YRPYDPRGNSPYLRSNTWGERD-DSPNTV---RQPENP LOXAF30_28_PE11 NOISO LP---HPSHGSRGSVFYSE---YNPYDPRENSPYLRSNTWDERG-DSLNTM---RQPENP MACMU5_61_PE10 NOISO LP---HPSHGSRGRVFYPE---YNPYDPRENSPYRRSNTWDERD-DSPNTM---GQKESS MICMUGS_4254_PE3 NOISO LP---HPSHGYRGSVFYPE---YNPYGPRENSPYLRNNMWDERD-DSPNTM---GPQENP MONDO5_19_PE8 NOISO LL---YPALGARENVPYPE---YVPYDPQRSSLYARGNMWDEGD-EFPGTFRPAGQPGNP MOUSE5_PE1333 NOISO LR---HPSYGSRGNIFYHE---YTNPYHNEKSQYIKSNPWDKS---SPSTM---MRPENP MYOLUGS_5518_PE3 NOISO LP---HPSHGSRADVYYPD---YNPYDPRENSPYIRSNTWDERD-DSPNNA---GLPEDP OCHPR4304_PE3 NOISO LP---PPSHGSRGSVFFHE---YRPYNPRENPPYLSSNTWGEIV-DSPSSI---RQPEHP ORNANULTRA362_3_PE5 ENSOANG00000013692 LT---YPPISPRSGIPYPD---HH--------PYDPKGTWDEGNEPTPSS-GPAEQPGRQ OTOGAGS_5066_PE4 NOISO LP---YPSHGTRGHVFYPE---YNSYTPQENSPYLRSSVWDERE-DSPNTM---GQQENP PANTR4_62_PE8 NOISO LP---HPSHGSRGSVFYPE---YNPYDPRENSPYLRGNTWDERD-DSPNTM---GQKESP PIG8_59_PE8 ENSSSCG00000008938 LP---HLSHGSRVHVYYPD---YNPYDPRENSPYLRSNTWYERD-DSPNTM---GQPENP PONPY4_76_PE4 NOISO LP---HPSHGSRGSVFYPE---YNPYDPRENSPYLRSNTWDERD-DSPNTM---GQKESP PROCA5980_PE1 NOISO LP---YPSHGTRGSVFYPE---YNSYDPREN-SYLRSNTCDERD-NSPNTI---RRPETS PTEVAGS_3629_PE3 NOISO LP---HPSRSSRGGMYYPY---YNPYDPRENSPYLRSNTWDERD-DSPNTV---GQPKNP RABIT15_81_PE10 NOISO LPPSPPPSHGSRGSVFFQK---YSPYDPRENPPYRRSNMWGEIV-DPPSTM---RQPENP RAT14_PE303 NOISO LR---HPPYGSRGNVFYHE---YNNPYPNEKSPYLRGNTWDKRI-STPGTM---MQPENP SORARGS_2951_PE1 NOISO VL---PPSHGSRGTMYYPD---YNPYDPRENPPYLRSNIWDERY-SPPNTM---GQPESS SPETR123914_PE1 NOISO LP---QPSQGSRGSVFYHE---YNPYYPRENLPYIRSNIWDERI-DSPNTI---RQPENP TARSYGS_3427_PE1 NOISO LP---HPS-GSRGNVFYPE---YTPYDPRENSPYLRSNTWDERD-DSPNTM---RQQENP TUPGBGS_5264_PE3 NOISO LP---HPSHGSRGSVFYPE---YNPYEPRESSPFPRSNTWDDRN-VSPNTM---GQPENP TURTRGS_3203_1_PE1 NOISO LP---HPSHGSGGRVYYPD---YNPYDPRENSPYPRSNTXXXXX-XXXXXX---XXXXXX MATCH : . . : : : . CONSENSUS LP????PS?GSRG?V?Y?????Y??Y?PREN?PY?R?N?WDE?????P?T??????????

AILMEGL192678_1_1_PE11 NOISO LYPINTPE-LKETVPYNEQDPVDAT-GDESFPGQSRWGMEETSFKEGPTVRHYEGEQYT- BOVIN6_91_PE10 NOISO HYPMNTPD-PKETIPYNEEGPADPT-GDETFPGQTRWSVDESNFKTAPTA-RYEGKQYT- CALJA3_131_PE14 ENSCJAG00000014627 LYPINTPD-QKETVPYNEEDPIDPT-GDEYFPGQYRWGE-ELSFKGSPTVRHYEGEQYT- CANFA13_64_PE23 NOISO LYPINTPE-LKETVPYNEEDPIDPT-GDETFPGQNRWGMEEPSFKEGPTVRHYEGEQYT- CAVPO47_4_PE5 NOISO QYPLKNTD-QKETIQYNEKDPSDPT-RHGPFPGLSRWGEEVLSFNERPMGRHNDGKQYA- DASNO2495_PE3 NOISO LYPMNTPD-QKKRIPYNEEDPADPT-GDETFPGQSRWGEEESNFKGDPTIRHYEGKQYT- DIPORGS_2762_PE1 NOISO QYVMNALD-QKATVHYMDKNP-DPT-GDE-FTEQNKWGEDEMDYKGGSKIRLFKGKQYA- ERIEUGS_3624_PE1 NOISO LYPMNTPD-PKDTVPYNEEDAADPT-GDVTYLRRSQWCMEESNFKGGPTVRQYEREQFT- GORGO4_82_PE22 NOISO LYPINTPD-QKETVPYNEEDPVDPT-GDEVFPGQNRWGE-ELSFKGGPTVRHYEGEQYT- HORSE3_67_PE10 NOISO LYPVNTPD-VKETVLYNEEDPTDPT-GGEAFPGQSRWGVEESSLKQGPTVRHYEGEQYT- HS4_PE1449 NOISO LYPINTPD-QKEIVPYNEEDPVDPT-GDEVFPGQNRWGE-ELSFKGGPTVRHYEGEQYT- LAMPAGS_3260_1_PE3 NOISO HYPMNTPH-PQETIHYNEEDPTDPT-GDEPFPGQSRWGAEESSFKGGPSVTIYEGQQYT- LOXAF30_28_PE11 NOISO LYPVNTPN-QKETVPYDEEDPIDPT-GDEHFPGPGRWAKEESSFKVSPTVRHYEGQQYA- MACMU5_61_PE10 NOISO LYPINTPD-HKETVPYNEEDPIDPT-GDEVFPGQNRWGE-ELSFKGGPTVRHYEGEQYT- MICMUGS_4254_PE3 NOISO LYPINTPD-QKGTVPYNEEDPIDPT-GDEPFPEQNRWGE-ELSFKGGPTVRHYEGEQHT- MONDO5_19_PE8 NOISO LHSLNSPSGQRHRSTDNEEDPIDPT-GDEFYRGPDAGG-KESNFKGSQ-VRYRERYPYAP MOUSE5_PE1333 NOISO QYTMTSLD-QKETEQYNEEDPIDPN-EDESFPGQSRWGDEEMNFKGNPTVRQYEGEHYA- MYOLUGS_5518_PE3 NOISO LYPMNTPD-PKETVPYNEEDPIDPT-GDEPFPGQSRWDVEESRFKEGAPVRHYKDEQYT- OCHPR4304_PE3 NOISO QYPLNTPE-QKKIVPYNEKDPIDPN-GDEIFQRQSTWDEEESSLKRAPTGRQYEGKQHT- ORNANULTRA362_3_PE5 ENSOANG00000013692 PSPCSPRMGQRGEVPYNEEDPVDPT-GDEPNLGPGPWEETA-NGKEDP-SRYHKSPQYPQ OTOGAGS_5066_PE4 NOISO LYPINTPD-QKGTVPYNEEDPIDPT-GDEPFPGQNRWGE-DLSFKEGPTTRHYEGERYT- PANTR4_62_PE8 NOISO LYPINTPD-QKETVPYNEEDPVDPT-GDEVFPGQNRWGE-ELSFKGGPTVRHYEGEQYT- PIG8_59_PE8 ENSSSCG00000008938 HYPMNTPD-PKETIPYNEEDPIDPT-GDEHFPGQSRWDMEELSFKEDPTVRHYEGEQYT- PONPY4_76_PE4 NOISO LYPINTPD-QKETIPYNEEDPIDPA-GDEVFPGQNRWGE-ELSFKGGPTVRHYEGEQYT- PROCA5980_PE1 NOISO LYPMNTPD-QKETVPYNEDDPTDPT-GDETFLDQGRWGKEESSFKESPQIRQYEGQRYA- PTEVAGS_3629_PE3 NOISO LYPTNTPD-PKE-TPYNEEDPMDPT-GVESFPGQRRWGVEESSFKEDPTVRHYEGEHYT- RABIT15_81_PE10 NOISO KYPMNTPD-QKET--YNEEDPIDPT-GDEIFPGQSTWGEEELSFKRDPTVRQYGGGQYA- RAT14_PE303 NOISO QYTMSSLD-QKETEQYNEEDPIDPN-EDESFPGQSRWGDDELSFKGNPTLRQYEGEQYT- SORARGS_2951_PE1 NOISO LFPMNTPD-PKETSPYNEEDPTDPTDGDESFTGQSRWGMEETRFKGGPSIKQYEGEQYN- SPETR123914_PE1 NOISO RYSMNTLV-QKETVHYNEEDPRDPT-GDESFPARSKWGEEELSFKGSPTVRLYEGEQYA- TARSYGS_3427_PE1 NOISO LYPINIPD-QKETVPYNEEDPVDPI-GDESFPGRNRWGE-ELRFKGGPTARYYEGEQYT- TUPGBGS_5264_PE3 NOISO LYPMNTPD-IKETVPYNEEDPTDPT-GDEPFPGQNRWGEEELSFKEGPTIRHYEGEQYT- TURTRGS_3203_1_PE1 NOISO XXXXXXXX-XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- MATCH CONSENSUS ?YP?N?????K????YNEEDP?DPT?GDE?F?????W???E??FK??P??R?YEG?QY??

AILMEGL192678_1_1_PE11 NOISO --SNQPKEYLPYSLDNPSKPREDFPYGEFYPWNPDEIFPSYNTAPTVPPPVESRGYY-AN BOVIN6_91_PE10 NOISO --SNQPKEYSPYSLDNLPKPREYFPYGEFYPWSPDENFPSYNTAPTIPLLVENRGYY-PT CALJA3_131_PE14 ENSCJAG00000014627 --SNQPKEYLPYSLDNPSKPKEDFYYSEFYPWSLDENIPSYNTAPTMSPPIESRGYY-LN CANFA13_64_PE23 NOISO --VNQPKEYLPYSLDNPSKTREDFPYGEFYPWNPDENFPSYNTAPTVPPPVESRGYY-AN CAVPO47_4_PE5 NOISO --SNQPKEYLPYPLDNPSKPREESPYTDFYPWSLDETFPSYSPGPTVSPPGKNRGHQ-VN DASNO2495_PE3 NOISO --PNQPKEYLHHSLDNPSKPREDFPYGEFYPWGPDENFPSYNTASTVPPPVESRGYY-VN DIPORGS_2762_PE1 NOISO --SNQPKEYFPYSLGNPSKPREDILYGELYPWNPDETFPSNSPGPTLSPPVENGDYY-LT ERIEUGS_3624_PE1 NOISO --SNQAKDYLPYPLDNPSKPREDFRYNEFYTH-RDETFPSYNTVPSVPPPVESRGYY-AS GORGO4_82_PE22 NOISO --SNQPKEYLPYSLDNPSKPREDFYYSEFYPWSPDENFPSYNTAPTMPPPIESRGYY-VN HORSE3_67_PE10 NOISO --SNQQKEYLPYSLDNPSKPREDFPYGEFYPWNPDENFLSYDTAPTVLPPVENKGYY-TS HS4_PE1449 NOISO --SNQPKEYLPYSLDNPSKPREDFYYSEFYPWSPDENFPSYNTASTMPPPIESRGYY-VN LAMPAGS_3260_1_PE3 NOISO --LNQPKEYLPYYLDNPSKPREDLPYGEFYPWNPDENFLSYNIAPTVPPPVESRGYY-VN LOXAF30_28_PE11 NOISO --SNQPKEYLPYSLDNPSKPKEDFPYGEFYHWGPDENFPPYNTAPTIPPPVESRGYF-VD MACMU5_61_PE10 NOISO --SNQPKEYPPYSLDNPSKPREDFYYSEFYPWNPDENFPSYSTAPTMSPPTESRGYY-VN MICMUGS_4254_PE3 NOISO --SNPPKEYLPYSLDNPSKPREDFPYGEFYPWSPDENFPSYNTAPTLPPPIESRGYY-AN MONDO5_19_PE8 NOISO SHPSKPKEYPQHSTDNLER-QRNPSYGEYYPWH----FPPYNFAPPLTPPRENSGYYYPP MOUSE5_PE1333 NOISO --STLAKEYLPYSLSNPPKPSEDFPYSEFYPWNPQETFPIYNPGPTIAPPVDPRSYY-VN MYOLUGS_5518_PE3 NOISO --SSRPKEYLPYSLDNPSKPREDFPYGEFYPWNADENFPSYNTIPTVPPPVENRGYY-AN OCHPR4304_PE3 NOISO --SNQPKQYLPYPVDRPSKPREDFPSNRFYPWNPDENFSSYNTGFTVSPPVETKGY--TN ORNANULTRA362_3_PE5 ENSOANG00000013692 SRATEPQDYPPYPEGGLEK-HRDFPYGDFYPRGPEDNLQPYNGADQL--PVEGRGYY-TH OTOGAGS_5066_PE4 NOISO --SNQPKEYLPYSLDNPPKPREDFPYSELYPWSPDENFPPYNTAPTGSPPIESRGYY-AN PANTR4_62_PE8 NOISO --SNQPKEYLPYSLDNPSKPREDFYYSEFYPWSPDENFPSYNTAPTMPPPIESRGYY-VN PIG8_59_PE8 ENSSSCG00000008938 --SNQPKEYLPYSLDNPSKPREDFLYGEFYPWNPEENFPSYNTAPTVSSPVESRGYY-AN PONPY4_76_PE4 NOISO --SNQPKEYLPYSLDNPSKPREDFYYSEFYPWSPDENFPSYNTAPTMSPPIESRGYY-VN PROCA5980_PE1 NOISO --SNQPKEYLHYSLDNPSKPREDFPYGEFYPWGPDENFPSYNTAPTLPPPVEGRGYY-IN PTEVAGS_3629_PE3 NOISO --SNQPKEYLPYSLDNPLKPTEDFPYGEYYPWNPDENFLSYNTVPTVPPPAENRGYY-AN RABIT15_81_PE10 NOISO --LNQPKEIFPYPADNPSKPKEDFPYNDFYPWSPDENFPSYNTGPTVTPPMQNKGYY-TT RAT14_PE303 NOISO --STLAKEYLPYSLSNPPKPSEDFPYSEFYPWNPHETFPIYNPGPTIAPPVDPRSYY-VN SORARGS_2951_PE1 NOISO --SNQPKEYLPYSFDNPLKPREDFPY-EFYPWNPEENFPSYTTVPSVLPPVENRGYY-TN SPETR123914_PE1 NOISO --SNQPKQYLPSSLDNPSKPREDFPYSEFYPWSPEETFPSYNPGPTISPPVENRGYY-GN TARSYGS_3427_PE1 NOISO --SNQPKEYLPYALDNPTKPREDFPYSEFSPWNPDENFLSYNTAPTMSPPIESRGYY-MN TUPGBGS_5264_PE3 NOISO --PNQPKEYLPYSLDNPSKPREDFPYREFYPWNPDDNFPSYNTAPTLSPPVESRGYY-AN TURTRGS_3203_1_PE1 NOISO --XXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX MATCH CONSENSUS ???N?PKEY?PY?LDNP?KP?EDF?Y?EFYPW?P?E?F??YN??PT??PP?E?RGYY???

AILMEGL192678_1_1_PE11 NOISO NAVGQEESTLFPSWNSWDHRIQTQGQNERQPYFNRNFWNQPTTLHKAPPSPPHQKENQPY BOVIN6_91_PE10 NOISO NAVGQEENTMFPSWNSWDHMVQVQGQKERRPYFTRTFWGQPTNLPKAPASPPYHKENQPY CALJA3_131_PE14 ENSCJAG00000014627 NAIGPEESTLFPSWNSWDHRIQAQGQKEIRPYFNRNTWDQATHLQKAPARPPDQKGNQPY CANFA13_64_PE23 NOISO NAVRQEESPLIPSWNSWDHRVQAQGQKERQPYFNRNYWDQPTTLHKAPPSPPHQKENQPY CAVPO47_4_PE5 NOISO NAMRQEGSALFPSPNSWDQGIQVQGQQESEPQFHRNYWDQATNLHEV--GPPNQRRNYPY DASNO2495_PE3 NOISO NAVGQEESTLFPSWNTWYNRIQAHGQKEGRPYVKENFWDEVPNLQKAPAISPDWKKNQHY DIPORGS_2762_PE1 NOISO NAIGQEESTLFPSWSSWDHRIQTQEQKEREPYFNKDFWEQSANLHTA--NLPDQNENYLY ERIEUGS_3624_PE1 NOISO NAIGQEESSPFPSWNSWTNRIQAQGQKERDPYFNRNFWDQSTNVYNAPTNPPHQKENQPY GORGO4_82_PE22 NOISO NAAGPEESTLFPSRNSWDHRIQAQGQRERRPYFNRKIWDQATHLQKAPARPPDQKGNQPY HORSE3_67_PE10 NOISO DVIGQEENTPFPSWNSWDHRIQAQGQKEIRPYFNINFWDQPTNLHKAPANPPHQKENQPY HS4_PE1449 NOISO NAAGPEESTLFPSRNSWDHRIQAQGQRERRPYFNRNIWDQATHLQKAPARPPDQKGNQPY LAMPAGS_3260_1_PE3 NOISO NAVEQEESTRFPHWNSWDHRIQAQGQKEIRPYFNRNFWDQPTNLHKVPTSSLH-QENKPY LOXAF30_28_PE11 NOISO NADEREESTLFPSWNSWDHRIQAQGPNERGPYFNRNFWDQTTNLHKAPASLPDYKESQPY MACMU5_61_PE10 NOISO NAVRPEESNLFPSWNSWDHRIQAHGQKERRPYFNRNIWDQATHLQKAPARPPDQKGNQPY MICMUGS_4254_PE3 NOISO SAVRQEESPLFPSQNSWDHRIQAQGQKERGPYFYRNFWDQATNLHRAPASPPEQKENQPY MONDO5_19_PE8 NOISO NALEQEESTPSPSWGSWDQKNYVPAKKGRIPYYNRYFWDQATNLHKSAASALEQREHQPH MOUSE5_PE1333 NOISO NAIGQEESTLFPSWTSWDHRNQAERQKESEPYFNRNVWDQSINLHKSNI------PNHPY MYOLUGS_5518_PE3 NOISO RPVGQEENSLFPSWNSWDHRIETQGQKERRPYFNRNFWDRPTNLHKAPASPPHQKENPHY OCHPR4304_PE3 NOISO NGVGQEGSTVFPSWNSWDYSIQTQGQKEKEPYYNRNFWNQATNLHEVPTTVPNLKETQLF ORNANULTRA362_3_PE5 ENSOANG00000013692 DAVGQGGPLQFPSRDSWDWGLRSAAQERRAPYDERDSWDHAINSPKSTAGAT---ETLSP OTOGAGS_5066_PE4 NOISO SAAGQEEGTLFPSWNSWDHRIQAQGQKERGPYFSRNFWDRAVNLDKAPASPPDQKEKHPY PANTR4_62_PE8 NOISO NAAGPEESTLSPSRNSWDHRIQAQGQRERRPYFNRNIWDQATHIQKAPARPPDQKGNQPY PIG8_59_PE8 ENSSSCG00000008938 NAVGQEESTMFPSWSSWDPRIQAQGQKEGRPYLNRNFWDQSTNLYKTPTSSPHQKENQPY PONPY4_76_PE4 NOISO NAAGPEESTLFPSRNSWDHRIQAQGQKERRPYFNRNIWDQATHLQKAPARPPDQKGNQPY PROCA5980_PE1 NOISO NAVEREVGPLFPSWNSWDHRIQAQGPEEKGPYFSRNFWDQTTNLHKAPAVLPDHNEIQPY PTEVAGS_3629_PE3 NOISO SAIGQEESTLLPSWNSWDQRIQAQGQEERRPYFNGNFGDQTTNLHKAPARPPHQKENQPY RABIT15_81_PE10 NOISO SAAEQEESTLFPSWNSWDYSFQAQEEKEKQPYYNRNYWDQATNLQQTPASIPDLKETQLY RAT14_PE303 NOISO NAVGQEESTLFPSWTSWDHRNQAERQKESEPYFNRNVWDQSMSLHKSNI----QNPNHPY SORARGS_2951_PE1 NOISO NAIGQEENSLFPSWSSWDHKTQGQGQKERGSYFNRNFWDQSTNLHKAPTSPPHQKENQPY SPETR123914_PE1 NOISO NAIGEEESTFFPSWNSWDHRIQPQGQKERESYFNRNFWDQATNSQKA--SLPDQKQNNPY TARSYGS_3427_PE1 NOISO NAVGKEESTLFPSSNSWDHRIQVQRQRERRPYFNRNFWDQGTYLQKTPVSPPDRKENQPY TUPGBGS_5264_PE3 NOISO NAIGQEESTLFPSWNSWDRRIQDQRQKEGGSYFNSNFWDRATNLHKVPPSPPDQKENQRY TURTRGS_3203_1_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXEQERPYFNRNFWDHATNLHKAPASSPYQKENKPY MATCH . . . CONSENSUS ?A???EE???FPS??SWD???Q???Q?E??PYF?RN?WDQ?T?L?K?????P???????Y

AILMEGL192678_1_1_PE11 NOISO PSNSPAGLQKNPTWHEGENLNYGM-QITRLNSPDGEHLAFPDLIPPNYPAGQKEAHVF-H BOVIN6_91_PE10 NOISO FSNSPTGLQKDPTWHEGENLNYGM-QITRLNSPEGGHLAFPDLIPPHYPGSQKETRLF-H CALJA3_131_PE14 ENSCJAG00000014627 SSNTPAGLQKNPIWHEGENLNYGM-QITRINSPEREHSSFRDFIPQSYPSGQKEAHLF-H CANFA13_64_PE23 NOISO PSNSPAGLQKNPTWREGENLNYGM-QITRLNSPEGEHLAFPDLIPPSYPAGQKEAHVF-H CAVPO47_4_PE5 NOISO PSQPHVGLQKTPTWQEGKNLNYDM-QMTRLYSPERSHLAFPDVMPQSYPLGQTESHLF-H DASNO2495_PE3 NOISO FSNYPNRLQKNPKWHEDGNLNYGM-QITRLNSPEGKHLAFPELIPQNYPTGQDEANLF-H DIPORGS_2762_PE1 NOISO PKNSPVGLQKNPPWHEDENLNYDL-QITRLTLPEREHLAFPDLIPQIYPSSQKEAHLF-H ERIEUGS_3624_PE1 NOISO SSNYPAGLQKNPTWNEGENLNYGM-QNTRLNSPEREHSSFPDLIPSNHPAGQKEPHSF-H GORGO4_82_PE22 NOISO YSNTPAGLQKNPIWHEGENLNYGM-QITRTNSPEREHSSFPNFIPPSYPSGQKEAHLF-H HORSE3_67_PE10 NOISO SSNSPAGLQKNPTWPEGENLNYGM-QITRLNSPEGEHVAFPDSIPLSYPAGQKEAHLF-H HS4_PE1449 NOISO YSNTPAGLQKNPIWHEGENLNYGM-QITRMNSPEREHSSFPNFIPPSYPSGQKEAHLF-H LAMPAGS_3260_1_PE3 NOISO SSNSPAGLQKNPTWHEGENLNYDI-QITRLNSPQREYLAFPELIPPSYPAGQKEAHLF-H LOXAF30_28_PE11 NOISO SSNSPAGLQKNPTWHDSENLNYGM-QITRLNSPEGDHLAFPDLIPQSYPADQEEANLF-H MACMU5_61_PE10 NOISO SSNTPVGLQKNPMWHEGEDLNYGM-QMTRMNSPEREYSSFPDFIPQSYPSGQKEAHLF-H MICMUGS_4254_PE3 NOISO SSHSPAGLQKNPTWHEDENLNYGM-QITRLNSPERKHLSFPDVIPQSYPSHQKEAHLF-H MONDO5_19_PE8 NOISO SSSFPAGLRGSLTYQETENLNYDSVHNNRINTPEKGQFPVTDSVIQNNLIYQGEVYSYSP MOUSE5_PE1333 NOISO STTSPARFPKDPTWFEGENLNYDL-QITSLSPPEREQLAFPDFLPQSYPTGQNEAHLF-H MYOLUGS_5518_PE3 NOISO SSNSPAGLQKNPIWREGENLNYGM-QNTRLNSPDNEHLAFQDLIPPSYSAGQKEAHLF-H OCHPR4304_PE3 NOISO YSNSLTRLQKNPTWHEGKHLNYGM-QIAGLNSPGREYLAYPDLITQSDPSSQKEIYVF-H ORNANULTRA362_3_PE5 ENSOANG00000013692 SHSVPAGIRGKPH-EESVDWSYRGGQVSDLGVPEAEGPALMEPVARSDPADPREASSYPV OTOGAGS_5066_PE4 NOISO SNNSPAGLQKNPVWREGDSWNYGM-QITRLNSPERKQVAFPDLIPQSYPSHQKEAHLV-H PANTR4_62_PE8 NOISO YSNTPAGLQKNPIWHEGENLNYGM-QITRMNSPEREHSSFPNFIPPSYPSGQKEAHLF-H PIG8_59_PE8 ENSSSCG00000008938 SNNSPAGLQKNPTWHEGENLNYGM-QITRLNSPERDHLAFPDLIPPDYPGGQKESHVF-H PONPY4_76_PE4 NOISO YSNTPAGLQKNPIWHEGENLNYGM-QITRTNSPEREHSSFPNFIPQSYPSGQKEAHLF-H PROCA5980_PE1 NOISO SSNSPVGLQKNPTWRDSENLNYGM-QITRLNSPEGERLAFPDLIPPSYSIDQKETNLF-H PTEVAGS_3629_PE3 NOISO FSNSPAGLQKNPTWREGENLNYGM-QITRLNSPEGEHLAFQDLIPPSYPAAQKEAHLF-H RABIT15_81_PE10 NOISO YTSSPAGLQKNPVWHEDENLNYGM-QITSLNSPDRDYLTYSDLITQNYPSSQKEIHLY-H RAT14_PE303 NOISO STTSPAGFPKDPTWLEGENLNYDL-QITSLSQPEREQLAFPDLRPQSYPTGQNEDHLF-H SORARGS_2951_PE1 NOISO SNNSPAGLQKNPIWQEGENVNYGM-EITRLNPTEGEHPSFPSLISQSLPAGQNEAHSF-N SPETR123914_PE1 NOISO SSNTPAGLQKNPTWQEGQNLNYDM-QITSLNSPERQHLAFPDFIPQSYPSGQKEAHLF-H TARSYGS_3427_PE1 NOISO FSNYPAGLQKNPTWHDGENLNYGV-QITRLNSPERERLAYPDIIRQSYPSGQKEAHLF-H TUPGBGS_5264_PE3 NOISO PSNSPAGLQKNPTWHDGEDFNYGM-QITRLNSPDREHLAFPDLIPQSYPPSQKEAHLF-H TURTRGS_3203_1_PE1 NOISO SSDSPAGLQKNPIWHEGENLNYGM-QTTRLNSPEREHLVFPDLIPPSYPAVQKGAHLF-H MATCH : : .* . . . CONSENSUS ????P?GLQKNP?W?E?ENLNY???Q?TR?NSPE?????FP??IP??YP??Q?E???F?H

AILMEGL192678_1_1_PE11 NOISO LSQRGPCCAGGSTGHKDN--ALALQDYTPSFGPASGENQDTSPLYTEDSHTKHARHTISP BOVIN6_91_PE10 NOISO LSQRGPCCAGGSIGPKDN--PLALQDYTLFFGLAPGENQDTSPLYTEDSHTKHERYTISP CALJA3_131_PE14 ENSCJAG00000014627 LSQRGSCCAGSSTGPKDN--PLALQDYTPSYGLAPGENQDTSPLYTEGSHTKHTRHIVSP CANFA13_64_PE23 NOISO LSQRGSCCAGGSPGHKDN--PLALQDYTPPFDLAPGENEDTSPLYTEDSHANHARDTISP CAVPO47_4_PE5 NOISO PNPSSSCCVGGAAGPHKN--PLALQDYTPSYGLAPGENHNTNPTYTESSHTTHTRPNVSP DASNO2495_PE3 NOISO LSQRSSCCAV--TRPKDN--PLALQEYTPSFSLVPGENKDTSPLNTEGTHTKHARHIISL DIPORGS_2762_PE1 NOISO QGQRGSCCIGGPIGPKDN--PMALQDYTPSYSLALGEKQDTNPMYTESSNTKYTRSVVSP ERIEUGS_3624_PE1 NOISO QTQRGPCCASDPTRHKDN--PLALQDYTPSFDLAPEENQDTSPMYTEDSHTKHARHTISP GORGO4_82_PE22 NOISO LSQRGSCCAGSSTGPKDN--PLALQDYTPSYGLAPGENQDTSPLYTDGSHTKQTRDIISP HORSE3_67_PE10 NOISO LSQRSPCCVGGSIGPEDN--PLALQDYTPSFGLLPGENQDTSLLYMEDSHTNHARDTISP HS4_PE1449 NOISO LSQRGSCCAGSSTGPKDN--PLALQDYTPSYGLAPGENQDTSPLYTDGSHTKQTRDIISP LAMPAGS_3260_1_PE3 NOISO LSQKSPCCAGASIGLKNN--LLALQDYTPSFGLAPGENQDTSPVYTEDSHTKHARYTTSP LOXAF30_28_PE11 NOISO LSQRGPCCAGGPTGPKDN--PLALQDYTPSFGLAPGENQDTSPLYTEGSHTKHARHIISP MACMU5_61_PE10 NOISO LSQRGSCCTGSSTGPKDN--PLALQDYTPSYGLAPGENQDTSPLYTEGSHSKHTRHIISP MICMUGS_4254_PE3 NOISO LSQRGSCCGSGSPGPKDD--PLALQVYTPSYSLAPGENQDTSPLYTEGGHTKHARHVVSP MONDO5_19_PE8 NOISO ASQRSPCCAGESPGPRES--PLISLDYSPPFGLVSGDDGERNPPTTEGIHMKHARHIIYS MOUSE5_PE1333 NOISO QSQRGSCCIGGSTGHKDN--VLALQDYTSSYGLPPRKNQETSPVHTESSYIKYARPNVSP MYOLUGS_5518_PE3 NOISO QRQRSPCCAGGSVGHKDN--PLALQDYTPSFGLAPGENQDTSPLYTKDSHTKHARHTISP OCHPR4304_PE3 NOISO QSQGSPCCTGGSTXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ORNANULTRA362_3_PE5 ENSOANG00000013692 AVARSSCCAGGSPGPRDV--PLAPPDYPPLARLSLWELQVGGPRSPGGSRSRHVQQAASP OTOGAGS_5066_PE4 NOISO LHHRGPCCAGGPTGPKDD--PLALQDYTPSYGLAPGEKQDASPLYTEGSHAKHARHVISP PANTR4_62_PE8 NOISO LSQRGSCCAGSSTGPKDN--PLALQDYTPSYGLAPGENQDTSPLYTDGSHTKQTRDIVSP PIG8_59_PE8 ENSSSCG00000008938 LSQRGPCCAGGSMWPKNN--PLALQDYTQSFGLAPGENPDTSTGYAEDSHIKYARQTVSP PONPY4_76_PE4 NOISO LSQRGSCCAGSSTGPKDN--PLALQDYTPSYGLAPGENQDTSPLYTEGSHTKQTRDTISP PROCA5980_PE1 NOISO PRQRGPCCAGGSTGPKDN--LLALQDYTPSLGLAPGENQDTSPLYTESSHTKHARHSISP PTEVAGS_3629_PE3 NOISO LSHRSPCCAGGSMGLKDN--LLAPQDYTPSFGLAPGEDRDISPVYTKDSH---VRHTISP RABIT15_81_PE10 NOISO QSQRGPCCTGGSTGPKDN--PLSLQAYTSSYGLAPEEKQDTNPLYTESSHTNNPSPIVSP RAT14_PE303 NOISO QSQRGSCCIGGSTGHKEN--VLALHDYTSSYGLPPRKTQEISPVHTESSYTKYAKPNVSP SORARGS_2951_PE1 NOISO PNHRGSCCVGGSMGQKDN--PLALQDYTPSFDVIPGENQDISLLYSEDIHTKHPRHTISP SPETR123914_PE1 NOISO HSPRGSCCVSGSTGHKDN--PLALQDYTSSYDLAPGENQATNPMYTESSLTKHTRPIVSP TARSYGS_3427_PE1 NOISO LSQRRPCCSGGSPGPKDN--PLALQDYTPSYGL--GENQDTSPLYTEDSHTQHARHIISP TUPGBGS_5264_PE3 NOISO LTQRGSCCTGGSTGPKDN--PLALQDYTPSYGLAPGENQDTSPQYTEGSHTKHARHVISP TURTRGS_3203_1_PE1 NOISO LSQRGPCCAGGSTGPKDN--PLALQDYTPSFGLALGENQDTSPVYIEDSQTTHVRHTISP MATCH .** CONSENSUS ??QR??CC?G?S?G?KDN???LALQDYT?S??L??GE?????P?YT??S?????R???SP

AILMEGL192678_1_1_PE11 NOISO TSNLPDQRNSSEQRLPGESQNPSPFRDDVSTLRRNTPCSMKNQLSQRGIMPFPEATSLQS BOVIN6_91_PE10 NOISO TSILPGQRNSSEKRLPGESQNPSPFRDDVSTLRRNTPCSINNQLSQRGIRPLPEASSLQS CALJA3_131_PE14 ENSCJAG00000014627 TNILPVQRNSSEKR---ESQNPSPFRDDVSTLRRNTPCSIKNQLDQKEIMPFPEAGSLQS CANFA13_64_PE23 NOISO ASNLPGQRNSSEKRMPAESQNLSPFRDDVSTLRRNTPCSMKNQLSQRGIMPFPEAGSLQS CAVPO47_4_PE5 NOISO TSILPGQRNSSEKKLPGESTKPSTLRDNVSSLK-NAPCSAKTQQGTGGVRSFPKASAPQS DASNO2495_PE3 NOISO VSTLSSQTNSSEKRLPGESQNPSPFRDYVSTLRRNTPYSINNQQGQREIMPLLEASSLQS DIPORGS_2762_PE1 NOISO TSILTDQRNNSEKELPGESQSPSLFRDHMSTMRRNTPCSIKNQLGQIGSMSFPDASTLQS ERIEUGS_3624_PE1 NOISO TSSLPGQRNSSEKRPPTESQNPSPFREDVSTPRRNTPCSMKNQLGQRGIMPFPEASSLQS GORGO4_82_PE22 NOISO TSILPGQRNSSEKR---ENQN--PFRDDVSTLRRNTPCSIKNQLGQKEIMPFPEASSLQS HORSE3_67_PE10 NOISO TIIPPVEGNSSEKRLPGESQNPSPFGDDVSPLRRNIPCSIKNQLGQRGIMPIPEASSLQP HS4_PE1449 NOISO TSILPGQRNSSEKR---ESQN--PFRDDVSTLRRNTPCSIKNQLGQKEIMPFPEASSLQS LAMPAGS_3260_1_PE3 NOISO MSILPGQRNSSEKRLPGESQNPSPFRDDVSTLRRNTPCSVKNQLSQRGIMPFPEASSLQS LOXAF30_28_PE11 NOISO TSILPDPRNSSEKTLPGESQNPSPFRDDVSTLRRNAPCSIKNQLGQRGMMPLPETSSLQ- MACMU5_61_PE10 NOISO TSTLPGQRNSSEKM---ENEN--PFRDDVSTLRRNTPCSINNQLGQKGIMPFPEVGSLQA MICMUGS_4254_PE3 NOISO TSILPGQRNSSEKRLPGESQDPSPLRDDTSTLRRSTPCSMKNQLAQRGLMPLPEASSLQS MONDO5_19_PE8 NOISO TDIQPNQRNSSEKNLSEKGANPDPFRADTAMLKKSSPCSKRSPAGQTESVPFSEADSLQ- MOUSE5_PE1333 NOISO ASILPSQRNISENKLTAESPNPSPFGDGVPTVRKNTPYSGKNQLE-TGIVAFSEASSSQP MYOLUGS_5518_PE3 NOISO TSSLPSQRNSSEKRQPGESQNPSPFRDDVSTLRRNIPCSIKNQLGQRGIMPFSEASSLQS OCHPR4304_PE3 NOISO XXXXXXXXXXXXXX---XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX ORNANULTRA362_3_PE5 ENSOANG00000013692 VGYPAIRRNGTEEAPPTRREEPAPSRDGLAP-GRSPPCSLRPRASPRAGLAFPEAGLPPA OTOGAGS_5066_PE4 NOISO AGVLPDQRNSSEKR---ESQSPSPVRDDVSILRRNTPCSSKNPVGQRGVVPFPEASSLQS PANTR4_62_PE8 NOISO TSILPGQRNSSEKR---ESQN--PFRDDVSTLRRNTPCAIKNQLGQKEIMPFPEASSLQS PIG8_59_PE8 ENSSSCG00000008938 TSIVPGQRNSSEKILPGESQNPSPFKDDVSTLRRSTPCSVKSQLSQRGIMPLPEANSLQS PONPY4_76_PE4 NOISO TSIIPGQRNSSEKR---ESQN--PFRDDVSTLRRNTPCSIKNQLGQKEIMPFPEASSLQS PROCA5980_PE1 NOISO TSILPDQRNSSEKRMPGESQNSSPFRDDVSTLRRNTPCSVKSQLGQMGMMPLPETSSLQ- PTEVAGS_3629_PE3 NOISO ASILPSQRNSSEKGLPGESQNPNPFRNDMSTLRRNIPCSIKNQPDQRESTPFPEASSLHS RABIT15_81_PE10 NOISO TSILPGQRNSSENRLPGEIQSPISFRDDVSTLRRNIPCSMKNQLSQLEIMS----NSPQS RAT14_PE303 NOISO ASILPNQRNISENKLTAESPNPSPFGDDVPTVRKNTPNSGKNQLE-TGIIALSEASSSQP SORARGS_2951_PE1 NOISO TGIIPSQRNSSDNGLPGESENLSHFGDDVSNMRKDTPCSLKSHLGHKGGAPSPEASPLHS SPETR123914_PE1 NOISO TNILPGQRNSSEKKLPGESQNTSPFREDVSTLRRNTPCSVKNQLDQTGMMSSSETSSPQS TARSYGS_3427_PE1 NOISO TSIIPGQRNSSEKRLPGESQSPSPFRDDVSTLRRNTPCSIKNQLGQRGIMPFPEAGSLQS TUPGBGS_5264_PE3 NOISO TSILPGQRNSSEKRVPGESQNASPFRDDVSTLRRNTPCSMKNQQGQRGVLPIPEASTLQP TURTRGS_3203_1_PE1 NOISO TSILAGQRNSSEKRLPGESQNPSPFRDDMSTLKRNTPRSI-NQLGQRGIMPFPETSSLQS MATCH CONSENSUS ????P?QRNSSE?????ES????PFRDD?S??RRN?PCS???Q??Q???????E??S?Q?

AILMEGL192678_1_1_PE11 NOISO KNMPCLTSDLGGDGNN-VLEQIFDDNQFNERTVDLTPEQLVIGTPDEGPQPEGIQSEV-Q BOVIN6_91_PE10 NOISO KNIPCLKSDLE-DGNH-VLEQTLEGNQLNERPVDLTPEQLVMDTPDEGPKPEGIPSEV-Q CALJA3_131_PE14 ENSCJAG00000014627 KNTPCLKNDLGGDGNN-ILEQIFEDNQLNERTTDLTPEQLVIGTPDEGSDPEGIQSQI-Q CANFA13_64_PE23 NOISO KNTPCLTSDLGGDGNN-VLEEIFEDNQLSERTVDLTPEQLVIGTPDEGPEPEGIQSEV-Q CAVPO47_4_PE5 NOISO -NTLCLSNDLGGDGNS-VLEQIFEGNHLSERTVNLTPEQLFIGTLNEGLKPPGIQKEM-Q DASNO2495_PE3 NOISO KNTHCLKIGLGGDGNN-VLGQIFEGNPINQRTAELTPEQLVISTPDKGPKPEGIQSKV-Q DIPORGS_2762_PE1 NOISO KNTPCLKNDLGEDRNN-DLEQIFESNQPDKRTVDLTPEQLVIGTPDKDPKPEGIQNEM-E ERIEUGS_3624_PE1 NOISO KNIPCLKSDIVGDGNNLVLEQIFEDNQLN---VGLTPEQLVMDTAADK--PEGIXXXX-X GORGO4_82_PE22 NOISO KNTPCLKNDLGGDGNN-ILEQVFEDNQLNERTVDLTPEQLVIGTPDEGSNPEGIQSQV-Q HORSE3_67_PE10 NOISO KNTPCLKSDLGGDGNN-VLERIFEGNQLNERTVDLTPEQLVIDIPDEGPKPEGIQSEV-Q HS4_PE1449 NOISO KNTPCLKNDLGGDGNN-ILEQVFEDNQLNERTVDLTPEQLVIGTPDEGSNPEGIQSQV-Q LAMPAGS_3260_1_PE3 NOISO KNIPCLKHDLGGDGNN-VLEQIFEGNQLNERTVDLTPEQLVIGTPEEVPKPEGIPGEV-Q LOXAF30_28_PE11 NOISO LNAPCLKSDLGGDENN-VKEQMFEDNQPNERTVDLIPEQLVIGTPDEDPTPEAIQSEV-L MACMU5_61_PE10 NOISO KNTPCLKNDLGGDGNN-ILEQIFEDNQLNERTVDLTPEQLVIGTPDEGSNPEGIQSQV-Q MICMUGS_4254_PE3 NOISO KNTPCLKSDLGGEGNN-VLEQIFEDNQLHERTVDLTPEQLVIGSPDEGPDPEGFQSEV-Q MONDO5_19_PE8 NOISO ANMPCRKSNLRGEGNN-VLAKILGVNQFNARTSNLIPEELE--APEENLGPENIQSEG-G MOUSE5_PE1333 NOISO KNTPCLKSDLGGDRRD-VLKQFFEGSQLSERTAGLTPEQLVIGIPDKGSGPDSIQSEV-Q MYOLUGS_5518_PE3 NOISO KNTPCLKNDLGGDGNN-ALEPIFEGNQLNERTVDLTPEQLVISTPDEGPKPEEIQSEV-Q OCHPR4304_PE3 NOISO XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ORNANULTRA362_3_PE5 ENSOANG00000013692 KPAPCFKSRLRGDVDS-VPEQILDPDPPVAGNDGPAPGDLAVVVPERDPGPVGIRGDPEP OTOGAGS_5066_PE4 NOISO KSTPCLKSDLGGDGSK-VLEQTFEDNQLNGRTVGLIPEQLVIGAPDEGPSPEGIQSEVVQ PANTR4_62_PE8 NOISO KNTPCLKNDLGGDGNN-ILEQVFEDNQLNERTIDLTPEQLV</