Alignment of the gene Family HOG000112590 of HOGENOM

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Isoforms are ON
BOVIN3_21_PE4 NOISO TNLLRSVVTVIDTFYKYTKQDGECGTLSKDELKELLEKEFRPILKNPDDPDTVDVIMHIL CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO PKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSL GORGO1_135_PE28 NOISO TDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKEF-------------------- HS1_PE4563 NOISO PKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSL HS1_PE4568 NOISO TDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKELHPVLKNPDDPDTVDVIMHML LOXAF11_42_PE2 ISOFORMIN TDLLRSVVTIIDIFYKYTRQDGECGTLSKEELKELLEKEFHPILKNPDDPDTVDVIMHML LOXAF11_42_PE3 ENSLAFG00000023048 TDLLRSVVTIIDIFYKYTRQDGECGTLSKEELKELLEKEFHPILKNPDDPDTVDVIMHML MOUSE3_PE1152 NOISO AYLLRSVVTIIDVFYKYTKQDEECGTLSKDELKELLEKEFRPILKNPDDPDTVDVIMHML MOUSE3_PE1159 ISOFORMIN PKLLESIVTVIDVFYQYATEYGNCDMLSKEEMKELLVTEFHQILKNPDDPDTVDIIMQNL MOUSE3_PE1160 ENSMUSG00000041991 PKLLESIVTVIDVFYQYATEYGNCDMLSKEEMKELLVTEFHQILKNPDDPDTVDIIMQNL MOUSE3_PE1161 ISOFORMIN PKLLESIVTVIDVFYQYATEYGNCDMLSKEEMKELLVTEFHQILKNPDDPDTVDIIMQNL OCHPR19810_PE1 NOISO SKLLQSIITTIDVFYQYAIQKGECDMLNKTELKELLENEFHQILKNPDDPDTVDVIMQSL PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO TDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKEFHPILKNPDDPDTVDVIMHML PANTR1_137_PE9 NOISO PKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSL TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO SKLIQCITTIIDIFYQYATPDGECEMLNKAELRELLENEFHQILKNPDDPDTVDVIMQNL MATCH CONSENSUS ??L?????T?ID?FY?Y?????????L?K?E??ELL??E?????????????????????

BOVIN3_21_PE4 NOISO DRDHDRRLDFTEFLLMVFKLAMACNKVLSKEYCKASGSKKHRHSHRHQEEESETEGEEED CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO DQDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQASGSKLRDDTHQHQEEQEETEKEENK GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO DRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENK HS1_PE4568 NOISO DRDHDRRLDFTEFLLMIFKLTMACNKVLSKEYCKASGSKKHRRGHRHQEEESETEEDEED LOXAF11_42_PE2 ISOFORMIN DRDHDRRLDFTEFLLMVFKLAMACNKVLSKEYCQASGSKKHRHGHQHQEEESETEEEEEE LOXAF11_42_PE3 ENSLAFG00000023048 DRDHDRRLDFTEFLLMVFKLAMACNKVLSKEYCQASGSKKHRHGHQHQEEESETEEEEEE MOUSE3_PE1152 NOISO DRDHDRRLDFTEFILMIFKLALACNKVLGKEYCKASGSKKHRRGHQHQEEESETEEE-EE MOUSE3_PE1159 ISOFORMIN DRDHNHKVDFTEYLLMILKLTKACNKIIGKDYCQASGSKQKNHSHQHQEEQSKKETENKE MOUSE3_PE1160 ENSMUSG00000041991 DRDHNHKVDFTEYLLMILKLTKACNKIIGKDYCQASGSKQKNHSHQHQEEQSKKETENKE MOUSE3_PE1161 ISOFORMIN DRDHNHKVDFTEYLLMILKLTKACNKIIGKDYCQASGSKQKNHSHQHQEEQSKKETENKE OCHPR19810_PE1 NOISO DRDHNKKVSFTEYLLMIYRLAHACNKIIGKDYCQASGSKQRDHSHQHQEEQNETEEREEN PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO DRDHDRRLDFTEFLLMIFKLTMACNKVLSKEYCKASGSKKHRRGHRHQEEESETEEDEED PANTR1_137_PE9 NOISO DRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENK TUPGB77060_PE1 NOISO --------------------SSSY-GHHGSTWGQSSGCEQSGSS---------------- TUPGBGS_5501_PE1 NOISO DHDHNKKVNFTEYLIMIFKLAKAFNKIMGKDYCQAAGSKQKGHSYQHQEEQSETEEEDGE MATCH CONSENSUS ????????????????????????????????????G???????????????????????

BOVIN3_21_PE4 NOISO ASGQNSGYRYSSWSEGEEHGYSSEGSRGTPKHRHESGSRRLRRQGGLSSSENQKRSGKRH CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO --WQESSFSHSSWSAGENDSYSR-NVRGSLKPGTESISRRLSFQRDFSGQHNS------- GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO --RQESSFSHSSWSAGENDSYSR-NVRGSLKPGTESISRRLSFQRDFSGQHNS------- HS1_PE4568 NOISO TPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRY LOXAF11_42_PE2 ISOFORMIN TLGQKSGHRYSSWSEREKHGYGSGGSSGTVKHRRGSKSRRLGRRDGLSSSENEEGSEKRS LOXAF11_42_PE3 ENSLAFG00000023048 TLGQKSGHRYSSWSEREKHGYGSGGSSGTVKHRRGSKSRRLGRRDGLSSSENEEGSEKRS MOUSE3_PE1152 NOISO TPRQKSGFRFSSWSEGEEHGHSSGGSRGPAKHRRGSNSKRLERQDELSSSEE---SRKKH MOUSE3_PE1159 ISOFORMIN --QKG----SLSSSAGENDSYSR-GSRGSNKSKSKKLRKGKEQSSKQTTKSNSSDHENSE MOUSE3_PE1160 ENSMUSG00000041991 --QKG----SLSSSAGENDSYSR-GSRGSNKSKSKKLRKGKEQSSKQTTKSNSSDHENSE MOUSE3_PE1161 ISOFORMIN --QKG----SLSSSAGENDSYSR-GSRGSNKSKSKKLRKGKEQSSKQTTKSNSSDHENSE OCHPR19810_PE1 NOISO --EQESSSRYSSSSAGEKDSYSR-GSRGNQKQT-ESSSRKLRHQRGLSSSGHRQSSEERT PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO TPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRY PANTR1_137_PE9 NOISO --RQESSFSHSSWSAGENDSYSR-NVRGSLKPGTESISRRLSFQRDFSGQHNS------- TUPGB77060_PE1 NOISO --------------SGRSSGY--------------------GHQESSSG----------- TUPGBGS_5501_PE1 NOISO --QE-SSPSYSRGRAGEDDSYNK-GSRYL-KHRPRSSSQRKGHQEDLPS----------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO H----GSSSGYSWSNGKERHGSSSEELEASYAR--------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ------------------------------------------------------------ HS1_PE4568 NOISO H----RSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGH LOXAF11_42_PE2 ISOFORMIN H----GSHSGHFWSSGKERHGSRSEELGERRNKSSVSPS---GEEYEYGSGSKSRGRKAH LOXAF11_42_PE3 ENSLAFG00000023048 H----GSHSGHFWSSGKERHGSRSEELGERRNKSSVSPS---GEEYEYGSGSKSRGRKAH MOUSE3_PE1152 NOISO H----GSIFGHSWSSNKEKDGSRSEELGEKGDKSYDSPSRESEEEYESGYRLNHQGREGH MOUSE3_PE1159 ISOFORMIN DYEQGQHESGFSNSSGNGRP----------SSR--------------------------- MOUSE3_PE1160 ENSMUSG00000041991 DYEQGQHESGFSNSSGNGRP----------SSR--------------------------- MOUSE3_PE1161 ISOFORMIN DYEQGQHESGFSNSSGNGRP----------SSR--------------------------- OCHPR19810_PE1 NOISO DSSLG----HFKNSEKNKH----------------------------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO H----RSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGH PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------QKHGSSSKGSEDGGRESHACGSSNSGGCGRQKN--- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ------------------------------------------------------------ HS1_PE4568 NOISO GGLSCGLETSGHESNSTQSRIR-EQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQN--- LOXAF11_42_PE2 ISOFORMIN GGLSHGLEASGHESSSTQSRSG-GQSLRSSSGGSGDCGRQSHTCNSSNSEGYGRSQN--- LOXAF11_42_PE3 ENSLAFG00000023048 GGLSHGLEASGHESSSTQSRSG-GQSLRSSSGGSGDCGRQSHTCNSSNSEGYGRSQN--- MOUSE3_PE1152 NOISO SGLSCGLEKNKYELNYIQLRKGGEQKLGYNTSSSGNSKIQSHVYGFSNSSGCCRPKN--- MOUSE3_PE1159 ISOFORMIN ------------------------KASGFPQPGSEPGQSSS--SSTKGSGECYSSGNGKH MOUSE3_PE1160 ENSMUSG00000041991 ------------------------KASGFPQPGSEPGQSSS--SSTKGSGECYSSGNGKH MOUSE3_PE1161 ISOFORMIN ------------------------KASGFPQPGSEPGQSSS--SSTKGSGECYSSGNGKH OCHPR19810_PE1 NOISO ---------------------------GSQQ-------------HESGSGQNYLNR--RH PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO GGLSCGLETSGHESNSTQSRIR-EQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQN--- PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO --------TSSSCQAGRFGEQGNQSSYTQSGYQSGSS-GEGHRCISGGWAS--------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ----------CSGQSSSYGEKNSDSHQS----------------------S--------- GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ----------YSGQSSSYGEQNSDSHQS----------------------S--------- HS1_PE4568 NOISO --------ASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPE--- LOXAF11_42_PE2 ISOFORMIN --------ASSSCQAGRFGGLGNQSSCTQSGYESGSSEGQGHGGISGGQSSGCQFSGYSQ LOXAF11_42_PE3 ENSLAFG00000023048 --------ASSSCQAGRFGGLGNQSSCTQSGYESGSSEGQGHGGISGGQSSGCQFSGYSQ MOUSE3_PE1152 NOISO --------ASSSCQASRSQGQGNQSCRTQSNCQSGTSGGQGYGCVSEGQSSRCCQPK--- MOUSE3_PE1159 ISOFORMIN GSSSGGSAVSGSGHSNTYGKQGTGSRHSSSNRRSRS---------TSRESS--------- MOUSE3_PE1160 ENSMUSG00000041991 GSSSGGSAVSGSGHSNTYGKQGTGSRHSSSNRRSRS---------TSRESS--------- MOUSE3_PE1161 ISOFORMIN GSSSGGSAVSGSGHSNTYGKQGTGSRHSSSNRRSRS---------TSRESS--------- OCHPR19810_PE1 NOISO E--------STSSEHSGYGKHRSHSGQSSTQRTQES---------N----S--------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --------ASSSCQSHRFGGQGNQFSYIQSGCQSGINGGQGHGCVSGGQPSGCGQPE--- PANTR1_137_PE9 NOISO ----------YSCQSSSYGEQNSDSHQS----------------------S--------- TUPGB77060_PE1 NOISO -------------HSSRQGRHRSSSGSS----------------------S--------- TUPGBGS_5501_PE1 NOISO -------------QSFSSDQEWSDSKDS----------------------V--------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ----------GQKGYGSRTCGQPQNCGG-QQGTGSCQSSCCGQYGSGVSQSSTYGQHGSG CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ----------GH--------------------------SQCG---SGSGQSPNYGQHG-- GORGO1_135_PE28 NOISO --------------HPILKENFPQNCGG-QWRTGSSQS-SCGQYGSGGSQSCSNDQHEYG HS1_PE4563 NOISO ----------GR--------------------------GQCG---SGSGQSPNYGQHG-- HS1_PE4568 NOISO --SNPCSQSYSQRGYGARENGQPQNCGG-QWRTGSSQSSCCGQYGSGGSQSCSNGQHEYG LOXAF11_42_PE2 ISOFORMIN HNSGSSSQSSSHRGHESRARGQPQNSRGRQQGTGSSQSSCYEQYGSGVSQSSSYGQYEYG LOXAF11_42_PE3 ENSLAFG00000023048 HNSGSSSQSSSHRGHESRARGQPQNSRGRQQGTGSSQSSCYEQYGSGVSQSSSYGQYEYG MOUSE3_PE1152 NOISO --PRSCSQSSSQRGYGSKQCGQPQNCGR-QQRMGSSHSSCCGPYGSGATQSSGCGQQRMS MOUSE3_PE1159 ISOFORMIN ----------GSQEYSSG---SSEEPGF-THGSGRKNSSTCGKNGSYSGQSTGRHQQGFG MOUSE3_PE1160 ENSMUSG00000041991 ----------GSQEYSSG---SSEEPGF-THGSGRKNSSTCGKNGSYSGQSTGRHQQGFG MOUSE3_PE1161 ISOFORMIN ----------GSQEYSSG---SSEEPGF-THGSGRKNSSTCGKNGSYSGQSTGRHQQGFG OCHPR19810_PE1 NOISO ----------RQ--------------------------TTHG---SGSGRSSTFEECG-- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --SNSCSQSYSQRGYGARENGQPQNCGG-QWRTGSSQSSCCGQYGSGGSQSCSNGQHEYG PANTR1_137_PE9 NOISO ----------GR--------------------------SQCG---SGSGQSPNYGQHS-- TUPGB77060_PE1 NOISO ----------SY--------------------------GQHG---SHSGQPSGHGQHG-- TUPGBGS_5501_PE1 NOISO ----------EN--------------------------RQHK---KKSEKSANKRDER-- MATCH CONSENSUS ?????????????????????????????????????????????S????S?????????

BOVIN3_21_PE4 NOISO SCGYSSNSHQKRCGSNETSKCGQRRSSSGQSSGFGQHESGSGQYSGFGHC---------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ----T--------GSGQSSSNGPHGSGSGQSSGFGHHESGSGQSSGYSQHGSGSGHSS-- GORGO1_135_PE28 NOISO SCGRFSNSS----SSNEFSKCDQYGSGSGQSTSFEQHGTGLSQSSGFEQHVRGSGQT--- HS1_PE4563 NOISO ----S--------GSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSS-- HS1_PE4568 NOISO SCGRFSNSS----SSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQT--- LOXAF11_42_PE2 ISOFORMIN SCGSSSTSSQKRSGSNEFSKRGQLDPGSGHFSS--------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 SCGSSSTSSQKRSGSNEFSKRGQLDPGSGHFSS--------------------------- MOUSE3_PE1152 NOISO SCGHSSSSHQKGCSSNGFSKGDQRASGSGHSSCCEQHGTNSSQSSGFKQHGHESGQSC-- MOUSE3_PE1159 ISOFORMIN SSHEL--------ESGQSITSANHGSHSNQSSCSGTRECGSSESSMKKTHVSGSGHSSST MOUSE3_PE1160 ENSMUSG00000041991 SSHEL--------ESGQSITSANHGSHSNQSSCSGTRECGSSESSMKKTHVSGSGHSSST MOUSE3_PE1161 ISOFORMIN SSHEL--------ESGQSITSANHGSHSNQSSCSGTRECGSSESSMKKTHVSGSGHSSST OCHPR19810_PE1 NOISO ----S--------GLGQSTSNGQHSSTSGQSSCYDQHGSSSGQSSGYGQQGSGLGQSS-- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO SCGRFSNSS----SSNEFSKCGQYGSGSGQSTSFEQHGTGLSQSSGFEQHVCGSGQT--- PANTR1_137_PE9 NOISO ----S--------GSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHYS-- TUPGB77060_PE1 NOISO ----S--------ESGQSSRHSQHGSGEGQSSRHGRHESGSGQSSSYGHQGSTSGQSS-- TUPGBGS_5501_PE1 NOISO ----F--------SAGQSSRHSQHGSGEGQSSRHGRHESGSGQSSSYSHQGSTSGQSS-- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ----------------GCGSGQSSGFGHHESTSGQSCY-GQHGSGSCQYSGAGQYGSGSA CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------SYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSH GORGO1_135_PE28 NOISO -------------------------CGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSG HS1_PE4563 NOISO ------------------------GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSR HS1_PE4568 NOISO -------------------------CGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSG LOXAF11_42_PE2 ISOFORMIN ---------------------------QHRSSSSQSSGQHGSG---PSQSSYGQHGSGSH LOXAF11_42_PE3 ENSLAFG00000023048 ---------------------------QHRSSSSQSSGQHGSG---PSQSSYGQHGSGSH MOUSE3_PE1152 NOISO -------------------------CGQHGTASSQSSGYSQHRVGSGQSCHYGQHGSSSG MOUSE3_PE1159 ISOFORMIN GKYTSTSGQNYNSTRQGCGQGKSSGSEQYGASSGQSSGC-----SSGQSTRYGEQGSGSR MOUSE3_PE1160 ENSMUSG00000041991 GKYTSTSGQNYNSTRQGCGQGKSSGSEQYGASSGQSSGC-----SSGQSTRYGEQGSGSR MOUSE3_PE1161 ISOFORMIN GKYTSTSGQNYNSTRQGCGQGKSSGSEQYGASSGQSSGC-----SSGQSTRYGEQGSGSR OCHPR19810_PE1 NOISO ------------------------SYGHHSSTSGQSC-CGQHGSSSGQSSSYGQHGSGSS PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO -------------------------CGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSG PANTR1_137_PE9 NOISO ------------------------GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSC TUPGB77060_PE1 NOISO ------------------------GHSQHGSRSGQSSACGKPRSGSGSGSGSV-SGSG-- TUPGBGS_5501_PE1 NOISO ------------------------GHSQHGSRSGQSSACGKPRSGSGSGSG--------- MATCH CONSENSUS ????????????????????????????????S?QS???????????????????GS???

BOVIN3_21_PE4 NOISO QSSGFGHQ-------------------------------KSISGQ-STCVQHGSGSGQSS CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO QSSAHGRQ-------------------------------GSGPGQSPSHIRHGSGSGHSS GORGO1_135_PE28 NOISO QSSGFGQC------------------GPGSGQSPGFGQHASVSGQSSGFEQHGSVSGQSS HS1_PE4563 NOISO QSLGHGRQ-------------------------------GSGSRQSPSHVRHGSGSGHSS HS1_PE4568 NOISO QSSGFGQC------------------GSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSS LOXAF11_42_PE2 ISOFORMIN QSSGQHGSFTGQSSSQHRSSSSQSSSQHGSGTAQFSGQHGS-GSSQSSFNQHGSGSGQSS LOXAF11_42_PE3 ENSLAFG00000023048 QSSGQHGSFTGQSSSQHRSSSSQSSSQHGSGTAQFSGQHGS-GSSQSSFNQHGSGSGQSS MOUSE3_PE1152 NOISO QSSSSGRHGS------------------GSGQSSSSRHNRSGSSQSSGLEEHGSSSHQSH MOUSE3_PE1159 ISOFORMIN NSSTQSRG-------------------------------RSTSRESSTSQQFGSGSGRSS MOUSE3_PE1160 ENSMUSG00000041991 NSSTQSRG-------------------------------RSTSRESSTSQQFGSGSGRSS MOUSE3_PE1161 ISOFORMIN NSSTQSRG-------------------------------RSTSRESSTSQQFGSGSGRSS OCHPR19810_PE1 NOISO QSSSYGQH-------------------------------GSSSRQSSSHRQHGY------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO QSSGFGQC------------------GSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSS PANTR1_137_PE9 NOISO QSSGHGRQ-------------------------------GSGSRQSPSHVRHGSGSGHSS TUPGB77060_PE1 NOISO ---------------------------------------------------SSSGS---- TUPGBGS_5501_PE1 NOISO -----------------------------------------------------SGS---- MATCH CONSENSUS ?????????????????????????????????????????????????????S?S????

BOVIN3_21_PE4 NOISO SFGQPGS-------------S--------------------SGQSSGFEHHERR-SQQSG CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO SHGQHGSGSSCSSGRGHYESG--------------------SGQTSGFGQHESGSGQSSG GORGO1_135_PE28 NOISO GFGQHESRSRQSSYG-QHGSGSSQSSGYGQYGS---------RETSGFGQHGLGSGQSTG HS1_PE4563 NOISO SHGQHGSGSSYSYSRGHYESG--------------------SGQTSGFGQHESGSGQSSG HS1_PE4568 NOISO GFGQHESRSRQSSYG-QHGSGSSQSSGYGQYGS---------RETSGFGQHGLGSGQSTG LOXAF11_42_PE2 ISOFORMIN GFGQHGSGLSQSSYG-QHGSGSSQSSGQHGSCTGQSSSQHRSSSSQSSGQHGSGTGQFSG LOXAF11_42_PE3 ENSLAFG00000023048 GFGQHGSGLSQSSYG-QHGSGSSQSSGQHGSCTGQSSSQHRSSSSQSSGQHGSGTGQFSG MOUSE3_PE1152 NOISO S----------------------------------------------------------- MOUSE3_PE1159 ISOFORMIN GFSQGGSGQGRSSRGGQQGSF--------------------SGQTEGSQQHGSCCGQSSG MOUSE3_PE1160 ENSMUSG00000041991 GFSQGGSGQGRSSRGGQQGSF--------------------SGQTEGSQQHGSCCGQSSG MOUSE3_PE1161 ISOFORMIN GFSQGGSGQGRSSRGGQQGSF--------------------SGQTEGSQQHGSCCGQSSG OCHPR19810_PE1 NOISO --------------------E--------------------SGQSSGFGQQASRSRQSTG PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO GFGQHESRSRQSSYG-QHGSGSSQSSGYGQYGS---------RETSGFGQHGLGSGQSTG PANTR1_137_PE9 NOISO SHGQHGSGSSYSSSRGHYESG--------------------SGQTSGFGQHESGSGQSSG TUPGB77060_PE1 NOISO ---------GQSSGRGRHGSG--------------------SGRSPSPGHHGSGSGQSTG TUPGBGS_5501_PE1 NOISO ---------GQSSGRGRHSSG--------------------SGRSPSPGHHGSGSRQSTG MATCH CONSENSUS ????????????????????????????????????????????????????????Q??G

BOVIN3_21_PE4 NOISO YGHHELGSGQSSGFGQHGSTSNQSSGFGQH-RSGSCQSSGFGHHEIGSDQSSSDSERHSE CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO YSQHGFGSGDSSSQGQHGSMSGQASSSGQH-GSSSHQTSSYGQHESASHHSSGRGQHSSG GORGO1_135_PE28 NOISO FGQYGSGSGQSSGFGQHGSSSGQSSGFGQHESR-S-GQSSYGQHSSGSSQSSGYGQHGCR HS1_PE4563 NOISO YSKHGSGSGHSSSQGQHGSTSGQASSSGQH-GSSSRQSSSYGQHESASRHSSGRGQHSSG HS1_PE4568 NOISO FGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESR-S-GQSSYGQHSSGSSQSSGYGQHGSR LOXAF11_42_PE2 ISOFORMIN --QHGSGS-SQSSFGQHGSGSGQSSGFGQHGSG--------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 --QHGSGS-SQSSFGQHGSGSGQSSGFGQHGSG--------------------------- MOUSE3_PE1152 NOISO SGHHGSGSRQSSGSEQHGAVSGQS------------------------------------ MOUSE3_PE1159 ISOFORMIN YGQNEYGSGHSASSGQQGSHYSQSSSYGTH--------------NSGGSPSSSQRGHGSR MOUSE3_PE1160 ENSMUSG00000041991 YGQNEYGSGHSASSGQQGSHYSQSSSYGTH--------------NSGGSPSSSQRGHGSR MOUSE3_PE1161 ISOFORMIN YGQNEYGSGHSASSGQQGSHYSQSSSYGTH--------------NSGGSPSSSQRGHGSR OCHPR19810_PE1 NOISO SSQHGSGLSQSSSYGQQGST---------------------------TRQ---------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO FGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESR-S-GQSSYGQHSSGSSQSSGYGQHGSR PANTR1_137_PE9 NOISO YSQHGSGSGHSSSQGRHGSTSGQASSSGQH-GSSSRQSSSYGQHESASRHSSGRDQHSSG TUPGB77060_PE1 NOISO LERHGSGSGHSSSSSQHGSRSGQSSTYP-QGGSGSGQSSGYGQHGSGSGQSSGLGRHHSG TUPGBGS_5501_PE1 NOISO LDRHGSGSGHSSSSSQHGSRSGQSSTYGHKGGSGSGQSSGYGQHGSGSGQSSGLGRHHSG MATCH CONSENSUS ??????GS???????Q?GS???Q?????????????????????????????????????

BOVIN3_21_PE4 NOISO VSQRHSRSAHGQAGSQHGESGTTVRGRHGTGHGQLGDTSRHGHSRQGQSTRSGSRQRHS- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO SG---QSPGHGQHGSGSGQS--PSYGQHGSGFGRSSSSGPYVSG-SGYSSGLGHHES--- GORGO1_135_PE28 NOISO QT-----SGFGQHGSGSSQS--TGFGQYGSGSGQYSGFGQHVSG-SGQSCGFGEHESRSG HS1_PE4563 NOISO SG---QSPGHGQRGSGSGQS--PSSGQHGTGFGRSSSSGPYVSG-SGYSSGFGHHES--- HS1_PE4568 NOISO QT-----SGFGQHGSGSSQS--TGFGQYGSGSGQSSGFGQHVSG-SGQSSGFGQHESRSG LOXAF11_42_PE2 ISOFORMIN ----------------------------------------------------------LS LOXAF11_42_PE3 ENSLAFG00000023048 ----------------------------------------------------------LS MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN SG---RSSGLGQYGSPSGQT--SSSTRQGSGQGQASGSGRYGAS-SGQTSGCGSGQS--- MOUSE3_PE1160 ENSMUSG00000041991 SG---RSSGLGQYGSPSGQT--SSSTRQGSGQGQASGSGRYGAS-SGQTSGCGSGQS--- MOUSE3_PE1161 ISOFORMIN SG---RSSGLGQYGSPSGQT--SSSTRQGSGQGQASGSGRYGAS-SGQTSGCGSGQS--- OCHPR19810_PE1 NOISO -------SCCGQHGSSSGQS--SNYGQQGSGFN--------------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO QT-----SGFGQHGSGSSQS--TGFGQYGSGSGQSSGFGQHVSG-SGQSSGFGQHESRSG PANTR1_137_PE9 NOISO SG---QSPGHGQRRSGSEQS--PSSGQHGTGFGRSSSSGPYVSG-SGYSSGFGHHES--- TUPGB77060_PE1 NOISO SG---ESSGTGEYGSGSGQS--SSYGHHGSTWG--------------------------- TUPGBGS_5501_PE1 NOISO SG---ESSGTGEYGSGSGQS--SSYGHHGSTWG--------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO GSTHGQAGSQHGESGATVRGRHRTAHGQSGDTTRHGHSSHSGSTHGQAGSQHGESGTTVR CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------SSGHSSGYTQHGSDSGHSSGHGQQGCRSGQSS--RG GORGO1_135_PE28 NOISO HSSYGQHGFGSSQSS--GCGQRGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQS----- HS1_PE4563 NOISO ------------------------SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSS--RG HS1_PE4568 NOISO HSSYGQHGFGSSQSS--GYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQS----- LOXAF11_42_PE2 ISOFORMIN QSSYGQHGTSSSQSS--GQ--LGSCTGQSSS----QHRSSSSQSSGQHGSGTGQFSGQQG LOXAF11_42_PE3 ENSLAFG00000023048 QSSYGQHGTSSSQSS--GQ--LGSCTGQSSS----QHRSSSSQSSGQHGSGTGQFSGQQG MOUSE3_PE1152 NOISO -----------------------------SGSGKHETGPSQSSSSGHHGSGS-------- MOUSE3_PE1159 ISOFORMIN -TRYGEQGSGSRNSSTQSRGR--STSRESSTSQRYGSGSGESSGFSQGGSGQGRSS--RG MOUSE3_PE1160 ENSMUSG00000041991 -TRYGEQGSGSRNSSTQSRGR--STSRESSTSQRYGSGSGESSGFSQGGSGQGRSS--RG MOUSE3_PE1161 ISOFORMIN -TRYGEQGSGSRNSSTQSRGR--STSRESSTSQRYGSGSGESSGFSQGGSGQGRSS--RG OCHPR19810_PE1 NOISO ----------------------------------------QSSSYGEHGCASGQFF--QH PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO HSSYGQHGFGSSQSS--GYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQS----- PANTR1_137_PE9 NOISO ------------------------GSGHSSGYTQHGSGSGHSSGHGQHGSRSGQSS--RG TUPGB77060_PE1 NOISO ---------------------------QSSGCEQSGSSSGRSSGYGHQESGSGHSS--RQ TUPGBGS_5501_PE1 NOISO ---------------------------QSSGCEQSGSSSGRSSGYGHQESGSGHSS--RQ MATCH CONSENSUS ?????????????????????????????????????????S??????????G???????

BOVIN3_21_PE4 NOISO GRHRTAHGQSGDTSRHDHS------------SQGQSTWSGSSQERRQGSSHSEATDSGRH CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ERHRSSSGSPSSYGQHG------------------------------------------- GORGO1_135_PE28 NOISO ----------SGFGQHGSGSGQSSGFGQHESRSGQSSY-GQHSS-----GSSQSSGYGQ- HS1_PE4563 NOISO ERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPS-----PSR-----------GRH HS1_PE4568 NOISO ----------SGFGQHGSGSGQSSGFGQHESRSGQSSY-GQHSS-----GSSQSSGYGQ- LOXAF11_42_PE2 ISOFORMIN -----SGSSQSSFGQHGSGSGQSSG--QHVSGSSQSSY-SHHGS-----GSSQSSGFGQ- LOXAF11_42_PE3 ENSLAFG00000023048 -----SGSSQSSFGQHGSGSGQSSG--QHVSGSSQSSY-SHHGS-----GSSQSSGFGQ- MOUSE3_PE1152 NOISO -------------QQHGGGSGQSTGFGEHESSSGHSSSSGQHRS-----GSRHSSGSGK- MOUSE3_PE1159 ISOFORMIN GQQGSFSGQTSGRSQHQSGSR-------HGSGSGQFPI-----SGQQGSHHGHSSSSGTH MOUSE3_PE1160 ENSMUSG00000041991 GQQGSFSGQTSGRSQHQSGSR-------HGSGSGQFPI-----SGQQGSHHGHSSSSGTH MOUSE3_PE1161 ISOFORMIN GQQGSFSGQTSGRSQHQSGSR-------HGSGSGQFPI-----SGQQGSHHGHSSSSGTH OCHPR19810_PE1 NOISO RRHGSCSKRISGFSQHE------------------------------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ----------SGFGQHGSGSGQSSGFGQHESRSGQSSY-GQHSS-----GSSQSSGYGQ- PANTR1_137_PE9 NOISO ERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSDQSPS-----PSR-----------GHL TUPGB77060_PE1 NOISO GRHRSSSGSSSSYGQHGSHSGQASGHGQHGSESGQSSR-----H---------------- TUPGBGS_5501_PE1 NOISO GRHRSSSGSSSSYGQHGSHSGQASGHGQHGSESGQSSR-----H---------------- MATCH CONSENSUS ??????????????QH????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SHVSQSHSGSTHGQAGSQHGES-----------GTTVRGRHGTAHGQLGD---------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO -HGSR--QTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGHHESKSHQ HS1_PE4563 NOISO ESGSRQ-S-SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQ------------------- HS1_PE4568 NOISO -HGSR--QTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQ LOXAF11_42_PE2 ISOFORMIN -H---------------------------------------ESGSSQSS--GQHLSGSSQ LOXAF11_42_PE3 ENSLAFG00000023048 -H---------------------------------------ESGSSQSS--GQHLSGSSQ MOUSE3_PE1152 NOISO ----------------------------------------HESGRSQSSGSGHHGSG--- MOUSE3_PE1159 ISOFORMIN NSGSSQ-SSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASS-- MOUSE3_PE1160 ENSMUSG00000041991 NSGSSQ-SSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASS-- MOUSE3_PE1161 ISOFORMIN NSGSSQ-SSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASS-- OCHPR19810_PE1 NOISO ---------SSLGQSGSGSGQSSQYSQHVSGSSQSSSHSQQ------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO -HGSR--QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSHQ PANTR1_137_PE9 NOISO ESGSGQ-S-SSYGPHGSGSGRSSSRGPYESGSGHSSGLGHQ------------------- TUPGB77060_PE1 NOISO ------------SQHGSGEGQ-------------SSRHGRH------------------- TUPGBGS_5501_PE1 NOISO ------------SQHGSGEGQ-------------SSRHGRH------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------TTR---HGHSRHSGSTHGQAGSQHGESGATVRGRHRTAHGQSGDTTRH CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------SRHEHSADSS-- GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO SSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSG--FGQHGSGSGQSSGFGQH HS1_PE4563 NOISO ------ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS--CGQHGATSGQSSSHGQH HS1_PE4568 NOISO SSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSG--FGQHGSGSGQSSGFGQH LOXAF11_42_PE2 ISOFORMIN SSYGQHGSGSSQSSG--QHGSCTGQSSS--RHRS--SSSQS--SGQHGSGSSQSSGFGQN LOXAF11_42_PE3 ENSLAFG00000023048 SSYGQHGSGSSQSSG--QHGSCTGQSSS--RHRS--SSSQS--SGQHGSGSSQSSGFGQN MOUSE3_PE1152 NOISO --SQQHGGGSGNSTGFGEHGSSSHPLPSSGQNESSSGQSSR--SERHGTGSGQSSGFGQH MOUSE3_PE1159 ISOFORMIN --GQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESST--SQRYGSGSGGSSGFSQG MOUSE3_PE1160 ENSMUSG00000041991 --GQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESST--SQRYGSGSGGSSGFSQG MOUSE3_PE1161 ISOFORMIN --GQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESST--SQRYGSGSGGSSGFSQG OCHPR19810_PE1 NOISO ------GSGLGQSFRYGQHGSGSGHSSSHSQQGSISGQSSR--YGRHRSGSSQSSSHSQQ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------SRHQQSADSS-- PANTR1_137_PE16 NOISO SSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSG--FGQHGSGSGQSSGFGQH PANTR1_137_PE9 NOISO ------ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS--CGQHGATSGQSSRHGQH TUPGB77060_PE1 NOISO ------ESGSGQSSSYGHQGSTSGQSSGHSQHGSRSGQSSA--CGKPRSGSGSGS---GS TUPGBGS_5501_PE1 NOISO ------EFGSGQSSSYGHQGSTSGQSSGHSQHGSRSGQSSA--CGKPRSGSGSGS----- MATCH CONSENSUS ???????????????????G?????????????S???????????????????S??????

BOVIN3_21_PE4 NOISO GHSRQGQSTRSGSSQSHSGSTHGQAGSQHGESGTTVRGRHRTAHGQSGDTSRHDHSSQGQ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO -GTGSGQYSGFGQHESRS------------------------------------------ HS1_PE4563 NOISO -GSGSSQSSRYGQQGSGSGQS-------------PSRGRHGSDFGHSSSYGQHGS----G HS1_PE4568 NOISO -GTGSGQYSGFGQHESRS------------------------------------------ LOXAF11_42_PE2 ISOFORMIN -GSSSSQSSG--QHGYGI------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 -GSSSS------------------------------------------------------ MOUSE3_PE1152 NOISO -GSGSHQSSSSGHNEYGS------------------------------------------ MOUSE3_PE1159 ISOFORMIN -GSGQGRSSRGGQQGSFSGQT-------------EGSQQHGSCCGQSSGYGQNEY----G MOUSE3_PE1160 ENSMUSG00000041991 -GSGQGRSSRGGQQGSFSGQT-------------EGSQQHGSCCGQSSGYGQNEY----G MOUSE3_PE1161 ISOFORMIN -GSGQGRSSRGGQQGSFSGQT-------------EGSQQHGSCCGQSSGYGQNEY----G OCHPR19810_PE1 NOISO -GSGLGQSSRYSQHGSGSGHS-------------SSHSQQGSGLGTSSRYGQHGS----G PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO -GTGSGQYSGFGQHESRS------------------------------------------ PANTR1_137_PE9 NOISO -GSGSSQSSRHGQQGSGSGQS-------------PSRSRHGSDFGHSSSYGQHGS----G TUPGB77060_PE1 NOISO -GSGSGQSSGRGRHGSGSGRS-------------PSPGHHGSSWGQSTGLDRHGS----G TUPGBGS_5501_PE1 NOISO -GSGSGQSSGRGRHGSGSGRS-------------LSPGHHGSGSGQSTGLDRHGS----G MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO STWSGSSQERRQGSSHSEATDSGRHSHVSQSHSGSTHGQAGSQHGE--SGTTVRGRHGTA CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------GHSGTG GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO -----------------HQSSYGQH------GSGSSQSSGYGQHGSSSGQTFGFGQHRSG HS1_PE4563 NOISO SGWSSSNG--PHGSVSGQSSGFGHK-------SGSGQSSGYSQHGSGSSHSSGYRKHGSR HS1_PE4568 NOISO -----------------HQSSYGQH------GSGSSQSSGYGQHGSSSGQTFGFGQHRSG LOXAF11_42_PE2 ISOFORMIN -----------------GQSSYGQH------GSQSSQFS---------------EQHGSG LOXAF11_42_PE3 ENSLAFG00000023048 ------------------QSSYGQH------GSQSSQFS---------------EQHGSG MOUSE3_PE1152 NOISO -----------------------------------GQTSSSWPHGKGSGQESGYGEQESG MOUSE3_PE1159 ISOFORMIN SGHSASSG--QQGSHYSQSSSYGTH------NSGGSPSSSQRGHGSRSGRSSGLGQYGSP MOUSE3_PE1160 ENSMUSG00000041991 SGHSASSG--QQGSHYSQSSSYGTH------NSGGSPSSSQRGHGSRSGRSSGLGQYGSP MOUSE3_PE1161 ISOFORMIN SGHSASSG--QQGSHYSQSSSYGTH------NSGGSPSSSQRGHGSRSGRSSGLGQYGSP OCHPR19810_PE1 NOISO SGHSSSHS--QQGSISGQSSRYGQH------RSGSSQSSSHSQQGSGLGQSSRYGRHGSG PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------RHSGIG PANTR1_137_PE16 NOISO -----------------HQSSYGQH------GSGLSQSSGYGQHGSSSGQTFGFGQHRSG PANTR1_137_PE9 NOISO SCWSSSNG--PHGSVSGQSSSFGHK-------SGSGQSSGYSQHGSGSSHSSGYGNHGSR TUPGB77060_PE1 NOISO SGHSSSSS--QHGSRSGQSSTYGHK-------GGS------------------------- TUPGBGS_5501_PE1 NOISO SGHSSSSS--QHGSRSGQSSTYGHK-------GGS------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO HGQLGDTTRHGHSRQGQSTRSGSSQEGRRGYSHSEASDSERHAGVSERHSGSTHGQAGSQ CALJA18_7_PE23 ENSCJAG00000006405 RGQSSSAV---------------GHHAHTESSGSQASDSQAHSEDSDSQSVSGHRQAGHS GORGO1_135_PE25 NOISO ----------------------------------------------------------S- GORGO1_135_PE28 NOISO SGQS-----------------------------------------------SGFGQHGS- HS1_PE4563 NOISO SGQSSRSEQHG-----------------------------SSSGLSSS-----YGQHGS- HS1_PE4568 NOISO SGQS-----------------------------------------------SGFGQHGS- LOXAF11_42_PE2 ISOFORMIN SGQF-----------------------------------------------SGFGQHGS- LOXAF11_42_PE3 ENSLAFG00000023048 SGQF-----------------------------------------------SGFGQHGS- MOUSE3_PE1152 NOISO HGQSSSSWQHGTGPGQSSSSEE--EE--------------SRPGQ-----SSSSWQHGK- MOUSE3_PE1159 ISOFORMIN SGQTSSSTRQGSGQ-GQ--ASG---SGR--YGASSGQTSGCGSGQSTR-----YGEQGS- MOUSE3_PE1160 ENSMUSG00000041991 SGQTSSSTRQGSGQ-GQ--ASG---SGR--YGASSGQTSGCGSGQSTR-----YGEQGS- MOUSE3_PE1161 ISOFORMIN SGQTSSSTRQGSGQ-GQ--ASG---SGR--YGASSGQTSGCGSGQSTR-----YGEQGS- OCHPR19810_PE1 NOISO SSQSSSHSQQG-----------------------------SISGQSSR-----YGRHRS- PANTR1_137_PE12 ENSPTRG00000001312 HGQASSAV---------------RDSGHRGYSGSQASDSEGHSEDSDTQSVSAHGQAGSH PANTR1_137_PE16 NOISO SGQS-----------------------------------------------SGFGQHGS- PANTR1_137_PE9 NOISO SGQSSRSEQHR-----------------------------SSSGLSSS-----YGQRGS- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ??Q?????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO HGESGATVRGRHRTAHGQSG---------------------DTTRHGHSSHSGSTHGQAG CALJA18_7_PE23 ENSCJAG00000006405 QQSHHESAWGQSGERSGRSGPFLYQV---------------------------TTHEQSE GORGO1_135_PE25 NOISO -GSRQSSGHGRQGSGSGQSP---------------------SRGRHGSGSGHSSSHGQHR GORGO1_135_PE28 NOISO -GSGQSSGFGQHESGSGQSSGFGQ---------HESRSSQSNYGQHGSGSSQSSGYGQHG HS1_PE4563 NOISO -GSHQSSGHGRQGSGSGHSP---------------------SRVRHGSSSGHSSSHGQHG HS1_PE4568 NOISO -GSGQSSGFGQHESGSGKSSGFGQ---------HESRSSQSNYGQHGSGSSQSSGYGQHG LOXAF11_42_PE2 ISOFORMIN -GSGQSSGFKQYESRSSQSSGQHRSGSCQSSRQQGYGSSQSSYGQHGSGSGQS-SYGQHG LOXAF11_42_PE3 ENSLAFG00000023048 -GSGQSSGFKQYESRSSQSSGQHRSGSCQSSRQQGYGSSQSSYGQHGSGSGQS-SYGQHG MOUSE3_PE1152 NOISO -GSGQESGYGEQEAGHGQSSSSWQ----------------------------------HG MOUSE3_PE1159 ISOFORMIN -GSRNSSTQSRGRSTS-------------------------------------------- MOUSE3_PE1160 ENSMUSG00000041991 -GSRNSSTQSRGRSTS-------------------------------------------- MOUSE3_PE1161 ISOFORMIN -GSRNSSTQSRGRSTS-------------------------------------------- OCHPR19810_PE1 NOISO -GSSQSSSHSQQGSGLGQSS---------------------RYSQHGSGSGHSSGFGQSS PANTR1_137_PE12 ENSPTRG00000001312 QQSHQESARGRSGERSGRSGSFLYQV---------------------------STHEQSE PANTR1_137_PE16 NOISO -GSGQSSGFGQHESGSGKSSGFGQ---------HESRSSQSNYGQHGSGSSQSSGYGQHG PANTR1_137_PE9 NOISO -GSHQSSGHSRQGSGSGHSP---------------------SHVRNGSSSGHSSSHGQHR TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ??S???S?????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SQHGESGTTVRGRHGTAHGQSGDTSQHGHSRQGQSTWSG---SSQEGRQGSSHSETRDS- CALJA18_7_PE23 ENSCJAG00000006405 SAHGHSGRGTGGRQGSRHEHARDGSRHSASHEGQDTTGGQPGSSRGGRQGSHHEQSGDSS GORGO1_135_PE25 NOISO ----------------------SGSS--CSSSRGHYESG---SGQASGFGQHESGSG--- GORGO1_135_PE28 NOISO S-SSGQ--------TTGFGQH--RSSSGQYSGFGQHGSA---SGQSSGFGQHGTGSGQSS HS1_PE4563 NOISO ----------------------SGTS--CSSSCGHYESG---SGQASGFGQHESGSG--- HS1_PE4568 NOISO S-SSGQ--------TTGFGQH--RSSSGQYSGFGQHGSG---SDQSSGFGQHGTGSGQSS LOXAF11_42_PE2 ISOFORMIN C-RSSQ--------S-------------------------------S--GQHGPGISQ-S LOXAF11_42_PE3 ENSLAFG00000023048 C-RSSQ--------S-------------------------------S--GQHGPGISQ-S MOUSE3_PE1152 NOISO TGAGNQ--------SSGYGEH--KSGPSHSSRSWHHGTG---SGQSLGFGQHGKGSHQSE MOUSE3_PE1159 ISOFORMIN -------------------------R--ESSTSQRYGSG---SGESSGFSQGGSGQGRSS MOUSE3_PE1160 ENSMUSG00000041991 -------------------------R--ESSTSQRYGSG---SGESSGFSQGGSGQGRSS MOUSE3_PE1161 ISOFORMIN -------------------------R--ESSTSQRYGSG---SGESSGFSQGGSGQGRSS OCHPR19810_PE1 NOISO GLGKSS----------GHGQLGSGSN--QS--SNHSWQE---SNHSSGFSPQRSGSGQ-- PANTR1_137_PE12 ENSPTRG00000001312 SSHGWTGPSTRGRQGSRHEQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGYHHEQSVDSS PANTR1_137_PE16 NOISO S-SSGQ--------TTGFGQH--RSSSGQYSGFGQHGSG---SGQSSGFGQHGTGSGQSS PANTR1_137_PE9 NOISO ----------------------SGTS--CSSSCGHYESG---SGQASDFGQHESGSGQ-- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO --------------------ERHSEVSQSHSGSTHG-------QAGSQHG--E------- CALJA18_7_PE23 ENSCJAG00000006405 GHSGSHHRHSASQGRSDASRGHSGSRSASRQTRTQERSGDGFGHSGSHHHEASTRADSSR GORGO1_135_PE25 NOISO -------------------------------------------QGYSQHGSGS------- GORGO1_135_PE28 NOISO ------------------GFGQYESR-------SRQ-------S---------------- HS1_PE4563 NOISO -------------------------------------------QGYSQHGSAS------- HS1_PE4568 NOISO ------------------GFGQYESR-------SRQ-------S---------------- LOXAF11_42_PE2 ISOFORMIN ------------------SYGQHRS--------SSS-------Q---------------- LOXAF11_42_PE3 ENSLAFG00000023048 ------------------SYGQHRS--------SSS-------Q---------------- MOUSE3_PE1152 NOISO ------------------SSGHYESV-------SEP-------S---------------- MOUSE3_PE1159 ISOFORMIN ------------------RGGQQGSFSGQTSGRSQH-------QSGSRHGSGS------- MOUSE3_PE1160 ENSMUSG00000041991 ------------------RGGQQGSFSGQTSGRSQH-------QSGSRHGSGS------- MOUSE3_PE1161 ISOFORMIN ------------------RGGQQGSFSGQTSGRSQH-------QSGSRHGSGS------- OCHPR19810_PE1 NOISO -----------------------------------S-------SGYGQQGSGF------- PANTR1_137_PE12 ENSPTRG00000001312 GHSGSHHSHITSQGSSHASHGQSGSRSASRTTRNDEQSVDGSRHSGSRHHEASTHADISR PANTR1_137_PE16 NOISO ------------------GFGQYESR-------SRQ-------S---------------- PANTR1_137_PE9 NOISO -----------------------------------S-------SGYSQHGSGS------- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ----SGTT-----VRGRHGTAHGQSASCPGQTGDSSR-----------HSESHQGRHNSG CALJA18_7_PE23 ENSCJAG00000006405 HSQSGQEPSVGSRASRRRGSSVSQESDSEGHSE-----------------DSQRW----- GORGO1_135_PE25 NOISO ----GHFS-----SQGRHGSTSGQSSSSGQHGSSSGQSSSYGQHESASHHALGRGRHGSG GORGO1_135_PE28 NOISO -------------SYGQHGSGSIQSSGYGQHGSNSGQTSGFGQHRSGSGQSSGFGQYGSG HS1_PE4563 NOISO ----GHFS-----SQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSG HS1_PE4568 NOISO -------------SYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSG LOXAF11_42_PE2 ISOFORMIN -------------SSGQHGYGSSQSSGFSQHGSGSGQTSGFGQHELGSRQSSHSGQHSSG LOXAF11_42_PE3 ENSLAFG00000023048 -------------SSGQHGYGSSQSSGFSQHGSGSGQTSGFGQHELGSRQSSHSGQHSSG MOUSE3_PE1152 NOISO -------------------------SSSWQHGNGSGESYGYGEHESGHGQSSSAWNHGNE MOUSE3_PE1159 ISOFORMIN ----GQFP-----ISGQQGSHHGHSSSSGTHNSGSSQSS------------STQWSHGSG MOUSE3_PE1160 ENSMUSG00000041991 ----GQFP-----ISGQQGSHHGHSSSSGTHNSGSSQSS------------STQWSHGSG MOUSE3_PE1161 ISOFORMIN ----GQFP-----ISGQQGSHHGHSSSSGTHNSGSSQSS------------STQWSHGSG OCHPR19810_PE1 NOISO ----SQSS-----SYGQHGSTSGQSSCCGQHESSSG------------------------ PANTR1_137_PE12 ENSPTRG00000001312 HSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSE-----------------DSERW----- PANTR1_137_PE16 NOISO -------------SYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRSGSGQSSGFGQYGSG PANTR1_137_PE9 NOISO ----GHSS-----SQGQCGSMSGQSSSYGQHGSSSGQSSSYGQHESASRHASGCGRHGSG TUPGB77060_PE1 NOISO -----------------------------------------------------------G TUPGBGS_5501_PE1 NOISO -----------------------------------------------------------G MATCH CONSENSUS ??????????????????G??????S????H?????????????????????????????

BOVIN3_21_PE4 NOISO RQSVTTHGRPGSSSRNQHGSSHGQTGDSSRHSESHQRSHSEAVHESSRNQHGSSHGQSGD CALJA18_7_PE23 ENSCJAG00000006405 ---------SGSGSREHHGSAREQSRDGSRHRGSHHGD-------------RAGHGHSAE GORGO1_135_PE25 NOISO SGQSPGHG--------QHGSGSGQSPSYGRH--------------------GSGSGQSS- GORGO1_135_PE28 NOISO LGQSSGFG--------QHGSGTGKSSGFAQH--------------------EYRSGQSS- HS1_PE4563 NOISO SGQSPGHG--------QRGSGSGQSPSYGRH--------------------GSGSGRSS- HS1_PE4568 NOISO SGQSSGFG--------QHGSGTGKSSGFAQH--------------------EYRSGQSS- LOXAF11_42_PE2 ISOFORMIN SGQSPSFE--------PQGSSSGKLSSSGQH--------------------RS------- LOXAF11_42_PE3 ENSLAFG00000023048 SGQSPSFE--------PQGSSSGKLSSSGQH--------------------RS------- MOUSE3_PE1152 NOISO SGQSNGFG--------ENESGPDQRHSGSGH--------------------GHGQGQGQ- MOUSE3_PE1159 ISOFORMIN SEQSSGLG--------HYGSTSGQTASSTRH--------------------RSGQGQAS- MOUSE3_PE1160 ENSMUSG00000041991 SEQSSGLG--------HYGSTSGQTASSTRH--------------------RSGQGQAS- MOUSE3_PE1161 ISOFORMIN SEQSSGLG--------HYGSTSGQTASSTRH--------------------RSGQGQAS- OCHPR19810_PE1 NOISO -----------------------ETPSYNQH--------------------GSASGQFS- PANTR1_137_PE12 ENSPTRG00000001312 ---------SGSASRNHRGSAQEQSRDGSRHPRSHHED-------------RAGHGHSAD PANTR1_137_PE16 NOISO SGQSSGFG--------QHGSGTGKSSGFAQH--------------------EYRSGQSS- PANTR1_137_PE9 NOISO SGQSPGHG--------QRGYGSGQSPSYGRH--------------------GSGSGRSS- TUPGB77060_PE1 NOISO SGQSSGYG--------QHGSGSGQSSGLGRH--------------------HSGSGESS- TUPGBGS_5501_PE1 NOISO SGQSSGYG--------QHGSGSGQSSGLGRH--------------------HSGSGESS- MATCH : . * CONSENSUS ??????????????????GS??????????H????????????????????????G????

BOVIN3_21_PE4 NOISO SSRHSESHQ-----ERHSESVHGRSGSSTGQRQGSHHEQSRDSSRHSGTRHGQTSAESGN CALJA18_7_PE23 ENSCJAG00000006405 PSGRSGARHAETSSRGRAASSQQQATSSPGGRHGSRHEHSADSSGHSGTGRGQSSSAVGH GORGO1_135_PE25 NOISO --------------------SNGPHGSGSGQSSGFGHHE--------------------- GORGO1_135_PE28 NOISO ---------------------YGQHGTGSSQSSGCGQHE--------------------- HS1_PE4563 NOISO --------------------SSGRHGSGSGQSSGFGHKS--------------------- HS1_PE4568 NOISO ---------------------YGQHGTGSSQSSGCGQHE--------------------- LOXAF11_42_PE2 ISOFORMIN ---------------------------SISGKGSCGPTS--------------------- LOXAF11_42_PE3 ENSLAFG00000023048 ---------------------------SISGKGSCGPTS--------------------- MOUSE3_PE1152 NOISO ---------------------AGHQQ----RESVHGQRG--------------------- MOUSE3_PE1159 ISOFORMIN --------------------GSGRCGASSGQTSGCG------------------------ MOUSE3_PE1160 ENSMUSG00000041991 --------------------GSGRCGASSGQTSGCG------------------------ MOUSE3_PE1161 ISOFORMIN --------------------GSGRCGASSGQTSGCG------------------------ OCHPR19810_PE1 NOISO --------------------NHSRHVSGSRESSGFSQHE--------------------- PANTR1_137_PE12 ENSPTRG00000001312 SSRQSGTHHAETSSGGQAASSREQARSSPGERHGSRHQQSADSSRHSGIRRGQASSAVRD PANTR1_137_PE16 NOISO ---------------------YGQHGTGSSQSSGCGQHE--------------------- PANTR1_137_PE9 NOISO --------------------SSGRHGSGSGRSSGFGHNS--------------------- TUPGB77060_PE1 NOISO --------------------GTGEYGSGSGQSSSYGHHG--------------------- TUPGBGS_5501_PE1 NOISO --------------------GTGEYRSGSGQSSSYGHHG--------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO GRHRESSVSQASDSEGHTRDSGRHSETTHGRPGSSSRNQHGSSQGQTGDSSRYSSRNQHG CALJA18_7_PE23 ENSCJAG00000006405 HAHTESSGSQASDSQAHSEDSDSQSVSGHRQAGHSQQSHHESVRGQSGERSGRS-----G GORGO1_135_PE25 NOISO -----------------------------------------S---SSRQSSGYTQH---G GORGO1_135_PE28 NOISO ------------SGSGPTTGFGQHVSGSDNFSSSGQHI---S---DSG------------ HS1_PE4563 NOISO ---------------------------------------------SSGQSSGYTQH---G HS1_PE4568 NOISO ------------SGSGPTTSFGQHVSGSDNFSSSGQHI---S---DSG------------ LOXAF11_42_PE2 ISOFORMIN ------------G---------------KNYPKSGRTI---S---DSSHSQARSSSQERT LOXAF11_42_PE3 ENSLAFG00000023048 ------------D---------------HEVPSHEK------------------------ MOUSE3_PE1152 NOISO ------------RPQGPSQDSSRQPQASQGQPS------------Q-------------- MOUSE3_PE1159 ISOFORMIN ----------------------------------------------SGQSTRYDEQ---G MOUSE3_PE1160 ENSMUSG00000041991 ----------------------------------------------SGQSTRYDEQ---G MOUSE3_PE1161 ISOFORMIN ----------------------------------------------SGQSTRYDEQ---G OCHPR19810_PE1 NOISO -----------------------------------------S---GLGQSDRYGQQ---G PANTR1_137_PE12 ENSPTRG00000001312 SGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDRSGGRSGRS-----G PANTR1_137_PE16 NOISO ------------SGSGPTTGFGQHVSGSDNFSSSGQHI---S---YSG------------ PANTR1_137_PE9 NOISO ---------------------------------------------SSGQSSGYSQH---G TUPGB77060_PE1 NOISO -----------------------------------------S---TWGQSSGCEQS---G TUPGBGS_5501_PE1 NOISO -----------------------------------------S---TWGQSSGCEQS---G MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SVH----------------------------GQTRDSPRHSESHQERHSESVHGSSRNQH CALJA18_7_PE23 ENSCJAG00000006405 PFLYQVTTHEQSESAHGHSGRGTGGRQGSRHEHSRDGSRHSASHEGQD------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO -----------------------------------------------------------Q HS1_PE4563 NOISO ------------------------------------------------------------ HS1_PE4568 NOISO -----------------------------------------------------------Q LOXAF11_42_PE2 ISOFORMIN KQGDSERSQGHSISGS---ESEDHDSTHQHRQQRQGSNEEGRVPGRQETRYSQTSDSEGQ LOXAF11_42_PE3 ENSLAFG00000023048 ------------------------------------------------------------ MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN ------------------------------------------------------------ MOUSE3_PE1160 ENSMUSG00000041991 ------------------------------------------------------------ MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 SFLYQVSTHEQSESTHGQTGTSTGGRQGSHHEQARDSSRHSASQEGQD------------ PANTR1_137_PE16 NOISO -----------------------------------------------------------Q PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO GSSQGQTGSGTGHGHASAGSGINRHRESSVSQASDREGHARDSGRQSVTTHGRPGSSSRN CALJA18_7_PE23 ENSCJAG00000006405 -TTGGQPGS---------SRGGRQG--SHHEQSGDSSGHSGSHHRH-TTSQGRSD----- GORGO1_135_PE25 NOISO --------SGS------------------------------------------------- GORGO1_135_PE28 NOISO STGFGQYGSGSGQ-----STG-----------------------------LGQGE--SQQ HS1_PE4563 NOISO --------SGS------------------------------------------------- HS1_PE4568 NOISO STGFGQYGSGSGQ-----STG-----------------------------LGQGE--SQQ LOXAF11_42_PE2 ISOFORMIN SDNWERYSASPHT-----SSRIDQRQQSSQRQSSDSEWQSEDSQRHSGSTHGQSG--SQQ LOXAF11_42_PE3 ENSLAFG00000023048 -------------------SGSSRRQQSSQRQSSDSEWQSEDSQRHSGSTHGQSG--SQQ MOUSE3_PE1152 NOISO ------------S-----GSGSSPRRSPVHPESSEGEEHSVVPQRHSGSGHGQGQAGHQQ MOUSE3_PE1159 ISOFORMIN --------SGSRNSS-TQSRGRSTSRESSTSQ---RFG--SGSGGSSGFSQGRSG----Q MOUSE3_PE1160 ENSMUSG00000041991 --------SGSRNSS-TQSRGRSTSRESSTSQ---RFG--SGSGGSSGFSQGRSG----Q MOUSE3_PE1161 ISOFORMIN --------SGSRNSS-TQSRGRSTSRESSTSQ---RFG--SGSGGSSGFSQGRSG----Q OCHPR19810_PE1 NOISO --------FGS------------------------------------------------- PANTR1_137_PE12 ENSPTRG00000001312 -TIHAHPGS---------SRGGRQGQGSHHKQSVDRSGHSGSHHSH-TTSQGRSD----- PANTR1_137_PE16 NOISO SSGFGQYGSGSGQ-----STG-----------------------------LGQGE--SQQ PANTR1_137_PE9 NOISO --------SGS------------------------------------------------- TUPGB77060_PE1 NOISO --------SSS------------------------------------------------- TUPGBGS_5501_PE1 NOISO --------SSS------------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO QHVSSHGQIGDSS--SHSETNQRSGSSTGQRQGSHHEQ--SRDSSRHSGTGHGQTS-AGS CALJA18_7_PE23 ENSCJAG00000006405 ---VSRGHSGSRSASRQTRTQERSGDGSGHSGSHHHEASTQADSSRHSQSGQE--PSVGS GORGO1_135_PE25 NOISO GHSSSYGQHGSRS--GQSSRGERHGYSSGSSSRYGQHG--S---GSCQSSGHGRQG-SGS GORGO1_135_PE28 NOISO ---------------------VESGSTVHGRQETTHGQ--TVNTTRHSQSGQGQSTQIGS HS1_PE4563 NOISO GHSSSYEQHGSRS--GQSSRSEQHGSSSGSSSSYGQHG--S---GSRQSLGHGQHG-SGS HS1_PE4568 NOISO ---------------------VESGSTVHGRQETTHGQ--TINTTRHSQSGQGQSTQTGS LOXAF11_42_PE2 ISOFORMIN ---------------------GESG--SSRRQGTSHEQ--SGDITRHASSGHGQLTESGS LOXAF11_42_PE3 ENSLAFG00000023048 ---------------------GESG--SSRRQGTSHEQ--SGDITRHASSGHGQLTESGS MOUSE3_PE1152 NOISO ---------------------R---ESVHGQRGRPQGP--SQDSSRQPQAGQGQPSQSGS MOUSE3_PE1159 ISOFORMIN GRSSRGGQQGSFS--GQTEGSQQHGSCCGQSSGYGQNE--Y---GSGHSASSGQQG-SHY MOUSE3_PE1160 ENSMUSG00000041991 GRSSRGGQQGSFS--GQTEGSQQHGSCCGQSSGYGQNE--Y---GSGHSASSGQQG-SHY MOUSE3_PE1161 ISOFORMIN GRSSRGGQQGSFS--GQTEGSQQHGSCCGQSSGYGQNE--Y---GSGHSASSGQQG-SHY OCHPR19810_PE1 NOISO NQSSSHSQQGSGL--GQSSRYGQHGSGSGHSSGFGQNQ--S---GLGQSSGHGQLG-SGS PANTR1_137_PE12 ENSPTRG00000001312 ---ASRGQSGSRSASRQTHDKEQSGDGSRHSGSRHHEASSWADSSRHSQAGQG--QSEGS PANTR1_137_PE16 NOISO ---------------------VESGSTVHGRQETTHGQ--TINTTRHSQSGQGQSTQTGS PANTR1_137_PE9 NOISO GHSSGYGQHGSRS--GQSSRSEQHGSSSGSSSSYGQHG--S---GSRQSLGHGQHG-SGS TUPGB77060_PE1 NOISO GRSSGYGHQESGS--GHSSRQGRHRSSSGSSSSYGQHG--S---HSGQASGHGQHG-SES TUPGBGS_5501_PE1 NOISO GRSSGYGHQESSS--GHSSRQGRHRSSSGSSSSYGQHG--S---HSGQASGHGQHG-SES MATCH : . CONSENSUS ????????????????????????G?????????????????????????G?GQ?????S

BOVIN3_21_PE4 NOISO GSSRHRESSVSQASDSEGHSEDSGRQNVTTHGRPGSSS----------RNQHGSSQGQTG CALJA18_7_PE23 ENSCJAG00000006405 RASRRRGSSVSQESDSEGHSEDSQRWSGSGS-----------------REHHGSAREQSR GORGO1_135_PE25 NOISO GQ-------------------------------SPSPS----------HGRHGSGSGQSS GORGO1_135_PE28 NOISO RVTRRRRSSQSENSDSEVHSRVSHRHSEHIHTQAGSHYP---KSGSTVRRRQGTTHGQRG HS1_PE4563 NOISO GQ-------------------------------SPSPS----------RGRHGSGSGQSS HS1_PE4568 NOISO RVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYP---KSGSTVRRRQGTTHGQRG LOXAF11_42_PE2 ISOFORMIN GTTRRRDSSHSQSSDSEQHSGDSQRHSESTHGQSGSQHG---ESGS--SRRQGSSHGHSG LOXAF11_42_PE3 ENSLAFG00000023048 GTTRRRDSSHSQSSDSEQHSGDSQRHSESTHGQSGSQHG---ESGS--SRRQGSSHGHSG MOUSE3_PE1152 NOISO GRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGHGQGQGQAGHQQRESVHGQRGRPQGPSQ MOUSE3_PE1159 ISOFORMIN SQS-----------------SSYG---THNSGGSPSSS----------QRGHGSRSGRSS MOUSE3_PE1160 ENSMUSG00000041991 SQS-----------------SSYG---THNSGGSPSSS----------QRGHGSRSGRSS MOUSE3_PE1161 ISOFORMIN SQS-----------------SSYG---THNSGGSPSSS----------QRGHGSRSGRSS OCHPR19810_PE1 NOISO NQ-------------------------------SSNHS---------------------- PANTR1_137_PE12 ENSPTRG00000001312 RTSRRQGSSFSQDSDSEGHSEDSERRSGSAS-----------------RNHRGSAQEQSR PANTR1_137_PE16 NOISO RVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYP---KSGSTVRRRQGTTHGQRG PANTR1_137_PE9 NOISO GQ-------------------------------SPSPS----------RGRHGSGSGQSS TUPGB77060_PE1 NOISO GQ-------------------------------SSRNS------------QHGSGEGQS- TUPGBGS_5501_PE1 NOISO GQ-------------------------------SSRHS------------QHGSGEGQS- MATCH CONSENSUS ????????????????????????????????????????????????????G???G???

BOVIN3_21_PE4 NOISO DSSRYSASHQGRH------------------------SESVHER---------------- CALJA18_7_PE23 ENSCJAG00000006405 DGSRHRGSHHGDRAGHGH------------SAEPSGRSGARHA---ETSSRGRAAS-SQQ GORGO1_135_PE25 NOISO SYGPHGSGS-GR------------------------------------------------ GORGO1_135_PE28 NOISO DTTRHGHSGHGQSTQTGSRTSGRQRFSYSDATDNEVHSGVSHRPHSQEQTHSQAGSQHGE HS1_PE4563 NOISO SYGPYRSGS-GW------------------------------------------------ HS1_PE4568 NOISO DTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGE LOXAF11_42_PE2 ISOFORMIN ETTRHDQSGHGQLTQSGSRTTERRDSSHSQSSDSEWQSEDSQRH--SGSTHAQSGSQQGE LOXAF11_42_PE3 ENSLAFG00000023048 ETTRHDQSGHGQLTQSGSRTTERRDSSHSQSSDSEWQSEDSQRH--SGSTHAQSGSQQGE MOUSE3_PE1152 NOISO DSSRQPQAGQGQPSQSGSGRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGHGQGQGQAGH MOUSE3_PE1159 ISOFORMIN GLGQYGSPS-GQ------------------------------------------------ MOUSE3_PE1160 ENSMUSG00000041991 GLGQYGSPS-GQ------------------------------------------------ MOUSE3_PE1161 ISOFORMIN GLGQYGSPS-GQ------------------------------------------------ OCHPR19810_PE1 NOISO -----------W------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 DGSRHPRSHHEDRAGHGH------------SADSSRQSGTHHA---QNSSGGQAAS-FHE PANTR1_137_PE16 NOISO DTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHEE PANTR1_137_PE9 NOISO SYGPYGSAS-GW------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO -STSRTGQRQGSHHEQSRDSSRQSGTGHGHASA-GSGI-NRHRESSVSQASDSEGHSED- CALJA18_7_PE23 ENSCJAG00000006405 QATSSPGGRHGSRHEHSADSSGHSGTGRGQSSSAVGHH-A-HTESSGSQASDSQAHSEDS GORGO1_135_PE25 NOISO -SSSRG----------------PYESGSGHS----SGL-GHR----------------E- GORGO1_135_PE28 NOISO S-ESTVHERHETTYGQTGEATGHGHSGHGQSTQTGSRTTGRQRTSHSES-TDSEVHSGVS HS1_PE4563 NOISO -SSSRG----------------PYESGSGHS----SGL-GHR----------------E- HS1_PE4568 NOISO S-ESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSES-SDSEVHSGGS LOXAF11_42_PE2 ISOFORMIN S-GS--SRRQGTSHEQSGDITRHASSGHGQLTESGSGTTGRRGSSHSQQSSDSEQHSGDS LOXAF11_42_PE3 ENSLAFG00000023048 S-GS--SRRQGTSHEQSGDITRHASSGHGQLTESGSGTTGRRGSSHSQQSSDSEQHSGDS MOUSE3_PE1152 NOISO QQRESVHGQRGRPQGPSQDSSRQPQAGQGQPSQSGSGRSPRRSPVHPESS-EGEEHSVVP MOUSE3_PE1159 ISOFORMIN -TSSST----------------RQGSGQGQA----SGS-GRYGA--------SSGQTSG- MOUSE3_PE1160 ENSMUSG00000041991 -TSSST----------------RQGSGQGQA----SGS-GRYGA--------SSGQTSG- MOUSE3_PE1161 ISOFORMIN -TSSST----------------RQGSGQGQA----SGS-GRYGA--------SSGQTSG- OCHPR19810_PE1 NOISO -Q----------------------ESQSQQS----SGF-SPQ----------------R- PANTR1_137_PE12 ENSPTRG00000001312 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDS-G-HRGSSGSQASDSEGHSEDS PANTR1_137_PE16 NOISO S-ESTVPERHETTYGQTGD--------HGQSTQRGCRTTGRRGSGHSES-SDSEVHSGGS PANTR1_137_PE9 NOISO -SSSRG----------------PYESGSGHS----SGL-GHR----------------E- TUPGB77060_PE1 NOISO -----------------------------------SRH-GRH----------------E- TUPGBGS_5501_PE1 NOISO -----------------------------------SRH-GRH----------------E- MATCH CONSENSUS ????????????????????????????G??????S????????????????????????

BOVIN3_21_PE4 NOISO -------SGRQNVTTHGR----PGSSSSNQHGSSHGQTGDSSRHSE-----SHQGSHGES CALJA18_7_PE23 ENSCJAG00000006405 DSQ--------SVSGHRQAGHSQQS----HHESARGQSGERSGRSGPFLYQVTTHEQSES GORGO1_135_PE25 NOISO -------SRSGQSSGYGQ----HGSSSG--HSSTHGQHGSTSGQS--------------S GORGO1_135_PE28 NOISO HRTHSREHTYGQARS--QHG-EPEFTVHERHGTTHGQTGDTTRHAH-----YHHGVTTQT HS1_PE4563 NOISO -------SRSGQSSGYGQ----HGSSSG--HSSTHGQHGSTSGQS--------------S HS1_PE4568 NOISO HRPQSQEQTHGQAGS--QHG-ESGSTVHGRHGTTHGQTGDTTRHAH-----YHHGKSTQR LOXAF11_42_PE2 ISOFORMIN QR--HSESTHGRSRS--QHG-ESGS--SRRQGSSHGQSGETTRHAN-----SGHGQLTQS LOXAF11_42_PE3 ENSLAFG00000023048 QR--HSESTHGRSRS--QHG-ESGS--SRRQGSSHGQSGETTRHAN-----SGHGQLTQS MOUSE3_PE1152 NOISO QRHSGSGHGHGQGQGQGQAGHQQRESVHGQRGRPQGPSQDSSRQPQ-----AGQGQPSQS MOUSE3_PE1159 ISOFORMIN -------CGSGQSTRYGE----QGSGSR--NSSTQSRGRSTSRES--------------S MOUSE3_PE1160 ENSMUSG00000041991 -------CGSGQSTRYGE----QGSGSR--NSSTQSRGRSTSRES--------------S MOUSE3_PE1161 ISOFORMIN -------CGSGQSTRYGE----QGSGSR--NSSTQSRGRSTSRES--------------S OCHPR19810_PE1 NOISO -------SGSGQSSGYRQ----HGSGFS--QSSSYGQHGSTTGQ---------------S PANTR1_137_PE12 ENSPTRG00000001312 DTQ--------SVSAHGQAGPHQQS----HQESTRGRSAERSGRSGSFLYQVSTHEQSES PANTR1_137_PE16 NOISO HRPQSQEQTHGQAGS--QHG-ESGSTVHGRHGTTHGQTGDTTRHAH-----YHHGKSTQR PANTR1_137_PE9 NOISO -------TRSGQSSGYGQ----HGSSSS--HSSTHGQHGSTSGQS--------------S TUPGB77060_PE1 NOISO -------SGSGQSSSYGH----QGSTSG--QSSGHSQHGSRSGQS--------------S TUPGBGS_5501_PE1 NOISO -------FGSGQSSSYGH----QGSTSG--QSSGHSQHGSRSGQS--------------S MATCH . . . . : . CONSENSUS ??????????G?????????????S??????????????????????????????????S

BOVIN3_21_PE4 NOISO VHQRSGSSTGQRQGSHHEQSRDSSRHSGTGHGETSTGSGSSRHRESSVSQSSDSKGHSRG CALJA18_7_PE23 ENSCJAG00000006405 AHGHSGRGTGGRQGSRHEHARDGSRHSASHEGQDTTGGQP---------------GSSRE GORGO1_135_PE25 NOISO SCGQHGASSGQS-----------S-----SHGQ--HGSG--------------------- GORGO1_135_PE28 NOISO -----GSRTTGRRGSGHSEYSDSEGYSRVSHTHSGHTHGQ-------------------- HS1_PE4563 NOISO SCGQHGASSGQS-----------S-----SHGQ--HGSG--------------------- HS1_PE4568 NOISO -----GSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQ-------------------- LOXAF11_42_PE2 ISOFORMIN -----GSRTTGRRDSSHSQSSDIEQHSGNSYRHSRSGHDQ-------------------- LOXAF11_42_PE3 ENSLAFG00000023048 -----GSRTTGRRDSSHSQSSDIEQHSGNSYRHSRSGHDQ-------------------- MOUSE3_PE1152 NOISO -----GSGRSPRRSPVHPESSEGEEHSVVPQRHSGSGHGH-------------------- MOUSE3_PE1159 ISOFORMIN TSQRYGSGSGES-----------S-----GFSQ--GGSGQGR--------------SSRG MOUSE3_PE1160 ENSMUSG00000041991 TSQRYGSGSGES-----------S-----GFSQ--GGSGQGR--------------SSRG MOUSE3_PE1161 ISOFORMIN TSQRYGSGSGES-----------S-----GFSQ--GGSGQGR--------------SSRG OCHPR19810_PE1 NOISO CCGQHGSSSGQS-----------S-----NYGQ--QGSG--------------------- PANTR1_137_PE12 ENSPTRG00000001312 AHGRTGPSTGGRQGSRHEQARDSSRHSASQEGQDTIHGHP---------------GSRRG PANTR1_137_PE16 NOISO -----GSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHSQ-------------------- PANTR1_137_PE9 NOISO SCGQHGASSGQS-----------S-----SHSQ--HGSG--------------------- TUPGB77060_PE1 NOISO ACGNALHTSGSS-----------S--------------G--------------------- TUPGBGS_5501_PE1 NOISO ACGKPRSGSGSG-----------S--------------G--------------------- MATCH . CONSENSUS ?????G??????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SEDQSFSFAQNWSDSNESLGNRQHKKKPSQSPSKEHHGFISGSCGGQDHWSNSSEPAGYG CALJA18_7_PE23 ENSCJAG00000006405 GRQGSHHEQS--GDSSGH-SGSHHRH----TVSQGRYDASRGHSGSRSA----------- GORGO1_135_PE25 NOISO --------------SSQSSGYGQQGSGSGQSPSRGRHGSSS-----------EHSSSYGQ GORGO1_135_PE28 NOISO -------------------ARSQHGES--ESIVHERHGTIHGQ----------------- HS1_PE4563 NOISO --------------SSQSSGYGRQGSGSGQSPGHGQRGSGS-----------RQSPSYGR HS1_PE4568 NOISO -------------------SGSQHGES--ESIIHDRHRITHGQ----------------- LOXAF11_42_PE2 ISOFORMIN -------------------SGSQHGES--GPS--RRQENFHGQ----------------- LOXAF11_42_PE3 ENSLAFG00000023048 -------------------SGSQHGES--GPS--RRQENFHGQ----------------- MOUSE3_PE1152 NOISO -------------------GQGQG------QAGHQQRESVHGQ----------------- MOUSE3_PE1159 ISOFORMIN GQQGSFS--GQTSGRSQHQSGSRHGSGSGQFPISGQQGSHH-----------GHSSSSGT MOUSE3_PE1160 ENSMUSG00000041991 GQQGSFS--GQTSGRSQHQSGSRHGSGSGQFPISGQQGSHH-----------GHSSSSGT MOUSE3_PE1161 ISOFORMIN GQQGSFS--GQTSGRSQHQSGSRHGSGSGQFPISGQQGSHH-----------GHSSSSGT OCHPR19810_PE1 NOISO --------------FNQSSSYGEHGCASGQFSSHRRH----------------------- PANTR1_137_PE12 ENSPTRG00000001312 GRQGSYHEQS--VDRSGH-SGSHHSH----TTSQGRSDASHGQSGSRSA----------- PANTR1_137_PE16 NOISO -------------------GGSQHGES--ESIVHDRHRITHGQ----------------- PANTR1_137_PE9 NOISO --------------SSQSSGYGRQGSGSGQSPGHGQRGSGS-----------RQSPSYGR TUPGB77060_PE1 NOISO --------------SGLSSGCGRHVSGSGWSLGQG------------------------- TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO HGYGSGQPSQQRWH-ESNSSEVSSYGQHR-SGSEQPSSSIQHGFGSGQSSGYGQHRSSSG CALJA18_7_PE23 ENSCJAG00000006405 ----S-RQTRTQERSGDGFGH-SGLHHHEASTRADSSRHSQSG--QEPSVGSRASRR--- GORGO1_135_PE25 NOISO HGSGSGCS-SSNGPHGSGSGQSSGFGHHE-SGSGQSSGYSQHGSGSGHSSGYGQHGSRSG GORGO1_135_PE28 NOISO -------T-------------------------GDTTRHAHSGHGQSTQTGSRTT----- HS1_PE4563 NOISO HGSGSGRS-SSSGQHGSGLGESSGFGHHE-SSSGQSSSYSQHGSGSGHSSGYGQHGSRSG HS1_PE4568 NOISO -------T-------------------------GDTTRHSYSGHEQTTQTGSRTT----- LOXAF11_42_PE2 ISOFORMIN -------S-------------------------GDTTKQAQSSHGQRTESGSRTA----- LOXAF11_42_PE3 ENSLAFG00000023048 -------S-------------------------GDTTKQAQSSHGQRTESGSRHT----- MOUSE3_PE1152 NOISO -------PVRPEVPT------------------QDSSRQPQADQGQPSQSGSGRS----- MOUSE3_PE1159 ISOFORMIN HNSGSSQSSSTQWSHGSGSEQSSGLGHYG-STSGQTASSTRQGSGQGQASGSGRCGASSG MOUSE3_PE1160 ENSMUSG00000041991 HNSGSSQSSSTQWSHGSGSEQSSGLGHYG-STSGQTASSTRQGSGQGQASGSGRCGASSG MOUSE3_PE1161 ISOFORMIN HNSGSSQSSSTQWSHGSGSEQSSGLGHYG-STSGQTASSTRQGSGQGQASGSGRCGASSG OCHPR19810_PE1 NOISO ---------------GSGSRESSGFSQHE-SSLGQ------SGSGSGQSSQYGQHGSGSS PANTR1_137_PE12 ENSPTRG00000001312 ----S-RQTRNEQQSGDGSRH-SGSSHHEASTQADSSRHSQSG--QGESAGSRRSRR--- PANTR1_137_PE16 NOISO -------T-------------------------GDTTRHSYSGHEQTTQTGSRTT----- PANTR1_137_PE9 NOISO HGSGSGRS-SSSGQHGSGLGKSSGFGHHE-SSSGQSSSYSQHRSGSGHSSGSGQHGSRSG TUPGB77060_PE1 NOISO -------------HCASRSCXXXXXXRHE-SGSGQSSSYSHQGSTSGQSSGHSQHGSRSG TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ??????????????????????????????????????????????????G?????????

BOVIN3_21_PE4 NOISO QSSGFSHHGTGIGQSSSYEQHSATSRQPPNCSQHGPSLGHSTSCGQYGSGSGQSSSCGQH CALJA18_7_PE23 ENSCJAG00000006405 -------RGSSVSQESDSE----------------------------------------- GORGO1_135_PE25 NOISO QSSRGERHRSSSGSPSSYGQHGSGSRQSSGHGRQGSGSGQSPSRGRRGSGSGHSSSHG-- GORGO1_135_PE28 NOISO --------------GRRSSGHSEYSDSEGHSG----------F-SQRPH-------SRGH HS1_PE4563 NOISO QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHG-- HS1_PE4568 NOISO --------------GRQRTSHSESTDSEVHSG----------G-SHRPH-------SREH LOXAF11_42_PE2 ISOFORMIN --------------ERRDSS---------------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 --------------ASTYGQSGSSSKQSVSNS----------T-RTYES-------SNEH MOUSE3_PE1152 NOISO --------------QRRSPVHPESSEGEEHSV----------V-PQRNS-----ESCHCH MOUSE3_PE1159 ISOFORMIN Q-----TSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFS-- MOUSE3_PE1160 ENSMUSG00000041991 Q-----TSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFS-- MOUSE3_PE1161 ISOFORMIN Q-----TSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFS-- OCHPR19810_PE1 NOISO QSSSHSQQGSGLGQSSRYGQHGSGSGHSSGFGQNQSGLGQSSG-------------HG-- PANTR1_137_PE12 ENSPTRG00000001312 -------QGSSVSQDSDSE----------------------------------------- PANTR1_137_PE16 NOISO --------------GRQRASHSESTDSEVHSG----------G-SHRPH-------SREH PANTR1_137_PE9 NOISO QSSRGERHGSSSGSSSRYGQHGSGSRQSSGH----------------------------- TUPGB77060_PE1 NOISO QSSACGKPRSGSGSG-----SGSGSGQSSGRGRHSSGSGRSPSPGHHGSGS--------- TUPGBGS_5501_PE1 NOISO ---------SGSGSG-----SSSGSGQSSGRGRHGSGSGRSPSPGHHGSSS--------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO STGSSQSLNHGQHRSESSQTSSYGQQRTVSGQSSGYRQHRSGSGESSGFNQHRTGLGQSS CALJA18_7_PE23 ENSCJAG00000006405 -----------------------------------------------GHSEDSQRWSGSG GORGO1_135_PE25 NOISO -----------QHRSGSSCSSSRGHYESGSGQASGFGQHESGSGQSSGYSQNSSGSGHSS GORGO1_135_PE28 NOISO THSQA----------------------------------------GSQHGES-----ESI HS1_PE4563 NOISO -----------QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFC HS1_PE4568 NOISO TYGQA----------------------------------------GSQHEEP-----EFT LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 SEDIP--------------------KHSVSHQ-----------RQTSPYGQS-----GYR MOUSE3_PE1152 NOISO CHDQ-------------------------------------------------------- MOUSE3_PE1159 ISOFORMIN -----------QGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSA MOUSE3_PE1160 ENSMUSG00000041991 -----------QGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSA MOUSE3_PE1161 ISOFORMIN -----------QGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSA OCHPR19810_PE1 NOISO -----------QLGSGSNQSSNHSWQESQSQQSSGFSPQRSGSGQSSGFNQQGSGLGQSS PANTR1_137_PE12 ENSPTRG00000001312 -----------------------------------------------AYPEDSERRSESA PANTR1_137_PE16 NOISO TYGQA----------------------------------------GSQHEEP-----EFT PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO -------------------------------------------RQSTGLDRHGSGSGHSS TUPGBGS_5501_PE1 NOISO -------------------------------------------GQSTGLDRHGSGSGHSS MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SYEQHGSTSGQSQNCGQH-GSNLGQSSSYGQHGSSQY--SGHSQH--------------- CALJA18_7_PE23 ENSCJAG00000006405 SREHHGSAREQSRDGSRHRGSHHGDRAGHGSSSSVFSDSSTSKEHVHCSSLSEDSEYWSG GORGO1_135_PE25 NOISO SQGQHGSMSGQSSSYGQHG-SSSGQSSSYGQHESASCHASGRGRHGSGS------GQSPG GORGO1_135_PE28 NOISO VDERHRTTHGQTGDTSGHS-----------Q--------SGHGQSTQSG------SS--- HS1_PE4563 NOISO SQGQHGSTSGQSSTFDQEG-SSTGQSSSYGHRGSGSSQSSGYGRHGAGS------GQSPS HS1_PE4568 NOISO VHERHGTTHGQIGDTTGHS-----------H--------SGHGQSTQRG------SR--- LOXAF11_42_PE2 ISOFORMIN --------HSQS------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 TSGRQGSPHVQRGDRSTHSGSIHGQSGSRTI--------SSSSHHQPGA------NH--- MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN SSGQQGSHYSQSSSYGT--------------HNSGGSPSSSQRGHGSRS------GRSSG MOUSE3_PE1160 ENSMUSG00000041991 SSGQQGSHYSQSSSYGT--------------HNSGGSPSSSQRGHGSRS------GRSSG MOUSE3_PE1161 ISOFORMIN SSGQQGSHYSQSSSYGT--------------HNSGGSPSSSQRGHGSRS------GRSSG OCHPR19810_PE1 NOISO SYGHHSSTSGQSCC-GQ-HGSSSGQSSSYGQHGSGSSQSSSYG----------------- PANTR1_137_PE12 ENSPTRG00000001312 SRNRHGSSREQSRDGSRHPGSSHRDTTRHVQSSPVQSDSSTAKEHGHFSSLSQDSAYRSG PANTR1_137_PE16 NOISO VHERHGTTHGQIGDTTGHS-----------H--------SGHGQSTQRG------SR--- PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO SSSQHGSRSGQSSTYGHKGGSGSGQSSGYGQHGSGSGQSSGL------------------ TUPGBGS_5501_PE1 NOISO SSSQHGSRSGQSSTYGHKGGSGSGQSSGYGQHGSGSGQSSGL------------------ MATCH CONSENSUS ??????????Q????????????????????????????S????????????????????

BOVIN3_21_PE4 NOISO -------------------------RSGSSQSSGHSRHGSGSGQSASFGQ--------HG CALJA18_7_PE23 ENSCJAG00000006405 IQPRGSDDISCSHTFYSDTTERHGGQSGSVWRHGSY-------------GSADYDYGQSG GORGO1_135_PE25 NOISO HGQRGSES--------GQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGH--------KS GORGO1_135_PE28 NOISO ------TT--------GR-RSGHSESSDSEVHSGGS--H----------THSGHPHSQAR HS1_PE4563 NOISO RGRHGSGS--------GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH--------HE HS1_PE4568 NOISO ------TT--------GRQRSSHSESSDSEVHSGVS--H----------THTGHTHGQAG LOXAF11_42_PE2 ISOFORMIN --------------------------NDSEWHSGVS--E----------RHTASTYGQSG LOXAF11_42_PE3 ENSLAFG00000023048 ------SQ--------SWSSQRQRHGSGQGWKHGSY--G----------R-AAYDYGESG MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN LGQYGSPS--------GQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQG MOUSE3_PE1160 ENSMUSG00000041991 LGQYGSPS--------GQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQG MOUSE3_PE1161 ISOFORMIN LGQYGSPS--------GQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQG OCHPR19810_PE1 NOISO -----------------------QHGSSSRQSSSHRQHGYESGQSSGFGQ--------QA PANTR1_137_PE12 ENSPTRG00000001312 IQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSY-------------GSADYDYGESG PANTR1_137_PE16 NOISO ------TT--------GRQRSSHSESSDSEVHSGVS--H----------THTGHTHGQAG PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ----------------------GRHHSGSGESSGTGEYGSGSGQSSSYGH--------HG TUPGBGS_5501_PE1 NOISO ----------------------GRHHSGSGESSGTGEYGSGSGQSSSYGH--------HG MATCH CONSENSUS ??????????????????????????S?????????????????????????????????

BOVIN3_21_PE4 NOISO S--------------STRESSGFGQHGSGLSQSSSYGQHG----------------STSR CALJA18_7_PE23 ENSCJAG00000006405 FSHSQDGSVHFNSNPEV------FKERYKIRKASSFVEDHPR--FHATYINRYPG--LYG GORGO1_135_PE25 NOISO S---------------SGQSSGYTQHGSGSGHSSSYGQHG----------------SRSG GORGO1_135_PE28 NOISO SQHG----------------------------------------ESESTVHKRHQTTH-G HS1_PE4563 NOISO S--------------SSWQSSGCTQHGSGSGHSSSYEQHG----------------SRSG HS1_PE4568 NOISO SQHG----------------------------------------QSESIVPERHGTTH-G LOXAF11_42_PE2 ISOFORMIN -----SSSKQ------------SGN-----------------------MVSERHGTTQHG LOXAF11_42_PE3 ENSLAFG00000023048 YGPSGGSRASN-HNSNQEDSSRVGNHKCVSGQSFTYSSIGGTSERHHQNKELRHGWRRQG MOUSE3_PE1152 NOISO ----------------------------------------------------------AG MOUSE3_PE1159 ISOFORMIN SGSRNSSTQSR-GRSTSRESSTSQRYGSGSGESSGFSQGG----------------SGQG MOUSE3_PE1160 ENSMUSG00000041991 SGSRNSSTQSR-GRSTSRESSTSQRYGSGSGESSGFSQGG----------------SGQG MOUSE3_PE1161 ISOFORMIN SGSRNSSTQSR-GRSTSRESSTSQRYGSGSGESSGFSQGG----------------SGQG OCHPR19810_PE1 NOISO S--------------RSRQSTGSSQHGSGLSQSSSYGQHG----------------STTG PANTR1_137_PE12 ENSPTRG00000001312 FRHSQHGSVSYNSNPVV------FKERSDICKASAFGKDHPR--YYATYINKDPG--LCG PANTR1_137_PE16 NOISO SQHG----------------------------------------QSESIVPERHGTTH-G PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO S--------------TWGQSSGCEQSGSSSGRSSGYGHQE----------------SSSG TUPGBGS_5501_PE1 NOISO S--------------TWGQSSGCEQSGSSSGRSSGYGHQE----------------SGSG MATCH CONSENSUS ???????????????????????????????????????????????????????????G

BOVIN3_21_PE4 NOISO QSSSCGQQRSNLGQSSSYGQHGSSSSQSSGHSQHGSGSGQSSSCGQ--H----------- CALJA18_7_PE23 ENSCJAG00000006405 HSRDTSKQ---------------------------------------------------- GORGO1_135_PE25 NOISO QSSRSEQHGSSSGSPSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH----------- GORGO1_135_PE28 NOISO QTGDTT------------------------------------------------------ HS1_PE4563 NOISO QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH----------- HS1_PE4568 NOISO QTGDTT------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN Q------------------------------------------TGK-------------K LOXAF11_42_PE3 ENSLAFG00000023048 QTSRPVRHGNATRPAGQYSIHGRNSRQESGHGRQASGTQQSGPPGTNHNGFTHHQSRGTR MOUSE3_PE1152 NOISO HQQRESVHGQRGRPEGP------------------------------------------- MOUSE3_PE1159 ISOFORMIN RSSRGGQQGSFSGQTSGRSQHQSGSR-------HGSGSGQFPISGQ--Q----------- MOUSE3_PE1160 ENSMUSG00000041991 RSSRGGQQGSFSGQTSGRSQHQSGSR-------HGSGSGQFPISGQ--Q----------- MOUSE3_PE1161 ISOFORMIN RSSRGGQQGSFSGQTSGRSQHQSGSR-------HGSGSGQFPISGQ--Q----------- OCHPR19810_PE1 NOISO QSCC-GQHGSSSGQSSNYGQQGSGFNQSSNYGEHGCASGQFSSHRR--H----------- PANTR1_137_PE12 ENSPTRG00000001312 HSSDISKQ---------------------------------------------------- PANTR1_137_PE16 NOISO QTGDTT------------------------------------------------------ PANTR1_137_PE9 NOISO -------------------------------GQHGSGSG----QSRGRH----------- TUPGB77060_PE1 NOISO HSSRQGRHRSSSGSSSSYGQHGSHSGQASGHGQHGSESGQSSRHSQ--H----------- TUPGBGS_5501_PE1 NOISO HSSRQGRHRSSSGSSSSYGQHGSHSGQASGHGQHGSESGQSSRHSQ--H----------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------GSS--------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------GSGSGQSSSYGPYG---------------- GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ------------------------------GSGSGQSSSYSPYG---------------- HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN --------R--------------------------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 HSGSNQEHRSDSQQSHSTHKYSLSAARGRQGSRHGHSVDSPTHSGSDQGEISSHGQSRSS MOUSE3_PE1152 NOISO ------------------------------------SQDSSRHPQAGQ------------ MOUSE3_PE1159 ISOFORMIN ------------------------------GSHHGHSSSSGTHN---------------- MOUSE3_PE1160 ENSMUSG00000041991 ------------------------------GSHHGHSSSSGTHN---------------- MOUSE3_PE1161 ISOFORMIN ------------------------------GSHHGHSSSSGTHN---------------- OCHPR19810_PE1 NOISO ------------------------------GSGSRESSGF-------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO ------------------------------GSGSGQSSSYGPYG---------------- TUPGB77060_PE1 NOISO ------------------------------GSGEG------------------------- TUPGBGS_5501_PE1 NOISO ------------------------------GSGEG------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO -------------------------------------SRESSGFGQHGSGLGQSSSYGQQ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO -------------------SGSGWSSSCGP-YESGSGSGHSSGLGHRESCSGQSSGYGQH GORGO1_135_PE28 NOISO ----EHGHPSHGQTTQTGSRTTG-RRGS--GHSEYSDSEGHSGVSHTHSGH--------- HS1_PE4563 NOISO -------------------SGSGWSSSRGP-YESG--SSHSSGLGHRESRSGQSSGYGQH HS1_PE4568 NOISO ----RHAHYHHGLTTQTGSRTTG-RRGS--GHSEYSDSEGYSGVSHTHSGH--------- LOXAF11_42_PE2 ISOFORMIN ----RNKHLKH-K-PKKGSRRTGRHRGS--SVSQASDSEGQSEDSHRQSGYTATH---YH LOXAF11_42_PE3 ENSLAFG00000023048 TKSTQESHQEHAA-DHPRHSGTGRHRGS--SVSQASDSEGQSEDSHRQSGYTATH---YH MOUSE3_PE1152 NOISO --------------GQPSQSGSGRSPRSSPVHPESSEGEEHSVVPQRHSGSGH-----GH MOUSE3_PE1159 ISOFORMIN -------------------SGSS-QSSSTQ-WSHGSGSEQSSGLGHYGSTSGQTASSTRQ MOUSE3_PE1160 ENSMUSG00000041991 -------------------SGSS-QSSSTQ-WSHGSGSEQSSGLGHYGSTSGQTASSTRQ MOUSE3_PE1161 ISOFORMIN -------------------SGSS-QSSSTQ-WSHGSGSEQSSGLGHYGSTSGQTASSTRQ OCHPR19810_PE1 NOISO -------------------------------------SQHESSLGQSGSGSGQSSQYGQH PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ----RHAHYHHGLTTQTGSRTTG-RRGS--GHSEYSDSEGYSGVSHTHSGH--------- PANTR1_137_PE9 NOISO -------------------SGSGWSSSRGP-YESG--SGHSSGLGHRESRSGQSSGYSQH TUPGB77060_PE1 NOISO ---------------------------------------QSSRHGRHEFGSGQSSSYGHQ TUPGBGS_5501_PE1 NOISO ---------------------------------------QSSRHGRHESGSGQSSSYGHQ MATCH CONSENSUS ?????????????????????????????????????????S??????S???????????

BOVIN3_21_PE4 NOISO GSTSGQ-----------------------------SSSCGQEGSNLGQSSSYGQHGSSQH CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO GSSSNH-----------------------------SSTHGQHGSTSGQSSSCGQHGASSG GORGO1_135_PE28 NOISO --THGQAGSH--------------------YPESGSSVHERHRTTHGQTADTTRHGHS-- HS1_PE4563 NOISO GSSSGH-----------------------------SSTHGQHGSTSGQSSSCGQHGASSG HS1_PE4568 NOISO --THGQARSQ--------------------HGESESIVHERHGTIHGQTGDTTRHAHS-- LOXAF11_42_PE2 ISOFORMIN GSTHGQ--------------------SHPAHGHSDSTARGRQSSSHGQSVDSSRHSSS-- LOXAF11_42_PE3 ENSLAFG00000023048 GSTHGQSRDSSRHLGSHQGRRADAPQSHPAHGHSDSTARGRQSSSHGQSVDSSRHSSS-- MOUSE3_PE1152 NOISO GQGQGQAGHQ-----------------------QRESVHGQRGRPQGPTQDSSRKPQA-- MOUSE3_PE1159 ISOFORMIN GSGQGQ-----------------------------ASGSGRCGASSGQTSGC-------- MOUSE3_PE1160 ENSMUSG00000041991 GSGQGQ-----------------------------ASGSGRCGASSGQTSGC-------- MOUSE3_PE1161 ISOFORMIN GSGQGQ-----------------------------ASGSGRCGASSGQTSGC-------- OCHPR19810_PE1 NOISO GSGSSQ-----------------------------SSSHSQQGSGLGQSSRYGQHGSGSG PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --THGQARSQ--------------------HGESES-IHERHGTIHGQTSDTTRHAHS-- PANTR1_137_PE9 NOISO GSSSGH-----------------------------SSTHGQHGSTSGQSSSCGQHGASSG TUPGB77060_PE1 NOISO GSTSGQ-----------------------------SSGHSQHGSRSGQSSACGKPRSGSG TUPGBGS_5501_PE1 NOISO GSTSGQ-----------------------------SSGHSQHGSRSGQSSACGKPRSGSG MATCH CONSENSUS ??????????????????????????????????????????????GQ????????????

BOVIN3_21_PE4 NOISO GSSQSSRNSQHRSGSSQSSSFGQHGFSSRESSGFGQHGSGLGQSSSYGQQGSTSGQSSSC CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO QSSSHGQ---HGSGSSQSSGYGRQGSGSGQSPGHGQHGSGSRQSPSYGRHGSGSGRSSSS GORGO1_135_PE28 NOISO -------------GHGQSTQRG-SRTTGRRASGHSE-------------YSDSEGHSGVS HS1_PE4563 NOISO QSSSHGQ---HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS HS1_PE4568 NOISO -------------GHGQSTQTG-SRTTGRRSSGHSE-------------YSDSEGHSGFS LOXAF11_42_PE2 ISOFORMIN -------------HQGETSPQEESRSST-------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 -------------HQGETSPQEESRSSTRGRQETQQ-------------EHSADHSRHSV MOUSE3_PE1152 NOISO -------------GQGQPSQSGSGRSPRRS-PVHPE-------------SSEGE--EHSV MOUSE3_PE1159 ISOFORMIN -------------GSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGGSSGF MOUSE3_PE1160 ENSMUSG00000041991 -------------GSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGGSSGF MOUSE3_PE1161 ISOFORMIN -------------GSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGGSSGF OCHPR19810_PE1 NOISO HSSSHSQ---QGSISGQSSRYGRHRSGSSQSSSHSQQGSISGQSSRYSQHGSGSGHSSGF PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO -------------GHGQSTQTG-SRTTGRRSSGHSE-------------YSDSEGHSGFS PANTR1_137_PE9 NOISO QSSSHGQ---HGSGSSQSSGY--------------------------------------- TUPGB77060_PE1 NOISO SGSGSGSGSGSSSGSGQSSGRGRHGSGSGRSPSPGHHGSSSGQSTGLDRHGSGSGHSSSS TUPGBGS_5501_PE1 NOISO SGSGSGS------GSGQSSGRGRHGSGSGRSPSPGHHGSGSGQSTGLDRHGSGSGHSSSS MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO GQEGSNLGQSSSYGQHGSSQ-------------------------HGSSQSSRNSQHRSG CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO GQHGSGLGESSG------------------------------------------------ GORGO1_135_PE28 NOISO HT--H-SG-----------------HAHGQAGSQHG------------------------ HS1_PE4563 NOISO GQHGSGLGESSG------------------------------------------------ HS1_PE4568 NOISO QRPHS-RG-----------------HTHGQAGSQHG------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 AEHGR-SLSESGAGRHRGSSVSQASDSEGQSEDSHR------------------------ MOUSE3_PE1152 NOISO VPQRH-SGSGHGHGH-----------GQGQGQAGHQ------------------------ MOUSE3_PE1159 ISOFORMIN SQGGSGQG---------------------------------------------------- MOUSE3_PE1160 ENSMUSG00000041991 SQGGSGQG---------------------------------------------------- MOUSE3_PE1161 ISOFORMIN SQGGSGQG---------------------------------------------------- OCHPR19810_PE1 NOISO GQNQSGLGQSCGYG-----------------------------------------QLRSG PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO QRPHS-RG-----------------HTHGQAGSQHG------------------------ PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO SQHGSRSGQSSTYGHKGGSG-SGQSSGYGQHGSGSGQSSGLGRHHSGSGESSGTGEYGSG TUPGBGS_5501_PE1 NOISO SQHGSRSGQSSTYGHKGGSG-SGQSSGYGQHGSGSGQSSGLGRHHSGSGESSGTGEYGSG MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SSQSSSFGQHGFSSRESSGFGQHGSGLGQSSSYGQHGSTSGQSSSCGQQRSNLGQSSS-- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------FGHHESSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGEQHRSSSGLSSS-- GORGO1_135_PE28 NOISO EPEFTVHERHGTTHGQTGDTTR-------HAHSGHGQSTQRGSRTAGRRGSGHSESSDSE HS1_PE4563 NOISO ------FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR-- HS1_PE4568 NOISO ESESIVDERHGTTHGQTGDTSG-------HSQSGHGQSTQSGSSTTGRRRSGHSESSDSE LOXAF11_42_PE2 ISOFORMIN -----RGHHHGSNHGQSRDSSR-------HSGYHQGHRA--------------------- LOXAF11_42_PE3 ENSLAFG00000023048 QSGSASGHHHGSNHGQSRDSSR-------HSGYHQGHRA--------------------- MOUSE3_PE1152 NOISO QRE-SVHGQRGRPQGPSQDSSR-------QPQAGQGQPSQSGSGRSPGRSPVHPESSEGE MOUSE3_PE1159 ISOFORMIN --RSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSS-- MOUSE3_PE1160 ENSMUSG00000041991 --RSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSS-- MOUSE3_PE1161 ISOFORMIN --RSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSS-- OCHPR19810_PE1 NOISO SNQSSCHSRQESQSQHSSGFSPQRSGTGQSSGYGQQASRSGQSSHSNQQGSGFGQSSS-- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ESESIVDERHGTTHGQTGDTSG-------HSQSGHGQSTQSGSSTTGRRRSGHSESSDSE PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO SGQSSSYGHHGSTWGQSSGCEQSGSSSGRSSGYGHQESSSGHSSRQGRHRSSSGSSSS-- TUPGBGS_5501_PE1 NOISO SGQSSSYGHHGSTWGQSSGCEQSGSSSGRSSGYGHQESGSGHSSRQGRHRSSSGSSSS-- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ---YGQHGSSQYGSSQSYSHSRHRSGSSQSSGHSQQGLGSSQSSSFGQH-GSSSRESSGF CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ---YGQHAS-----G---S--------HQSSGHGQQGSGSGHSPSRVRH-GSGSGHSSSH GORGO1_135_PE28 NOISO VHSGVSHTHS----GHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQT HS1_PE4563 NOISO ---YGQHGS-----G---S--------RQSSGHGRQGSGSGQSPSRGRH-GSGLGHSSSH HS1_PE4568 NOISO VHSGGSHTHS----GHTHSQARSQHGESESTVHKRHQTTHGQTG---------------- LOXAF11_42_PE2 ISOFORMIN ----------------DGPQSHSAHGQTDSTARGRQGPSYGHSVDSSRHSGSHQGEISTH LOXAF11_42_PE3 ENSLAFG00000023048 ----------------DGPQSHSAHGQTDSTARGRQGPSYGHSVDSSRHSGSHQGEISTH MOUSE3_PE1152 NOISO EHSVVPQRHSGS--GHGYGQGQAGHQQ-RESVHGQRGRPQGPSQDSSRQPQAGQGQPSQS MOUSE3_PE1159 ISOFORMIN ---YGTHNSGGSPSS---SQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQ-GSGQG----- MOUSE3_PE1160 ENSMUSG00000041991 ---YGTHNSGGSPSS---SQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQ-GSGQG----- MOUSE3_PE1161 ISOFORMIN ---YGTHNSGGSPSS---SQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQ-GSGQG----- OCHPR19810_PE1 NOISO ---YGQPSYGGCSSG---S--------GHSSCHNQQGTSSGQSTGYGQP-GSFSGHYSSH PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO VHSGGSHTHS----GHTHSQARSQHGESESTVHKRHQTTHGQTR---------------- PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ---YGQHGS-----H---S--------GQPSGHGQHGSESGQSSRHSQH-GSGEG----- TUPGBGS_5501_PE1 NOISO ---YGQHGS-----H---S--------GQASGHGQHGSESGQSSRHSQH-GSGEG----- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO GQHGSGLGQSSSFGQHGSTSGQSSGCG--------------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO GQHGSGSSCSSSRGHYESGSGQASGF--------GQ------------------------ GORGO1_135_PE28 NOISO GSR-TT---------------------------------------GRQ------------ HS1_PE4563 NOISO GQHGSGSGRSSSRGPYESRSGHSSVF--------GQ------------------------ HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN GQSRSS---------------------------------------TR------------- LOXAF11_42_PE3 ENSLAFG00000023048 GQSRSS---------------------------------------TRSRQES-HQEHSAD MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN --------QASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTS MOUSE3_PE1160 ENSMUSG00000041991 --------QASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTS MOUSE3_PE1161 ISOFORMIN --------QASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTS OCHPR19810_PE1 NOISO SQHVSGSGQC-------------------------------------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO --HESGSG--QGYSQHGSGSGHFSSQGRHGSTSGQSSSSGQHGSSSGQSSSYGQHESASH GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO --HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN -----------------------------------------------------------S LOXAF11_42_PE3 ENSLAFG00000023048 RSRRSGPGHARPSSESGAGRHRGSSVSQASDSEGQSEDS------------HRQSGSA-S MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN QRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQT-------------S-------GRS MOUSE3_PE1160 ENSMUSG00000041991 QRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQT-------------S-------GRS MOUSE3_PE1161 ISOFORMIN QRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQT-------------S-------GRS OCHPR19810_PE1 NOISO ----------PNYEQYGS------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO HALGRGRHGSGSGQSPGHGQHGSGSGQSPSYGRHGSGSGQSS-SNGPHGSGSGQSSGFGH GORGO1_135_PE28 NOISO ----RSSHSESSDSEVHSEASPTNSGH--P------HSQ-A---GSRH--GQSGSSGHGR HS1_PE4563 NOISO QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS-SSGRHGSGSGQSSGFGH HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN RHYHDSTHGQSRDSSRHSG---SHQGHRAD------GPQ-S---HPAH--GHSDSTARGR LOXAF11_42_PE3 ENSLAFG00000023048 RHYHDSTHGQSRDSSRHSG---SHQGHRAD------GPQ-S---HPAH--GHSDSTARGR MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN QHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGH MOUSE3_PE1160 ENSMUSG00000041991 QHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGH MOUSE3_PE1161 ISOFORMIN QHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGH OCHPR19810_PE1 NOISO ------------------------------------GPCSSS-SSEQHNYGYGQCSSSEQ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO -----GRQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS-SNGPHGSGSGQSSGFGH TUPGB77060_PE1 NOISO ---------------------------------------QSS-RHGRHESGSGQSSSYGH TUPGBGS_5501_PE1 NOISO ---------------------------------------QSS-RHGRHESGSGQSSSYGH MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO HESSSRQSSGYTQHGSGSGHSS-------------------------------------- GORGO1_135_PE28 NOISO QGTTHGQTGDTTRHAHY------------HHGVTTQTGSRTTGRRGSGHSEYSDSE---- HS1_PE4563 NOISO HESSSWQSSGYTQHGSGSGHSS-------------------------------------- HS1_PE4568 NOISO ---------DTTEHGHP------------SHGQTIQTGSRTTGRRGSGHSEYSDSE---- LOXAF11_42_PE2 ISOFORMIN QSSSHGQSVDSSRHSSS------------HQGETSAHGESRSST---------------- LOXAF11_42_PE3 ENSLAFG00000023048 QSSSHGQSVDSSRHSSS------------HQGETSAHGESRSSTRGRQETQQEHSADHSR MOUSE3_PE1152 NOISO -------------------------------------GSGRSPRRSPVHPESSEDEEH-- MOUSE3_PE1159 ISOFORMIN YGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSR MOUSE3_PE1160 ENSMUSG00000041991 YGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSR MOUSE3_PE1161 ISOFORMIN YGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSR OCHPR19810_PE1 NOISO YVPCSY------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ---------DTTEHGHP------------SHGQXTQTTTRH------------------- PANTR1_137_PE9 NOISO HESSSQQSSGYTQHGSGSGHSF-------------------------------------- TUPGB77060_PE1 NOISO QGSTSGQSSGHSQHGSRSGQSS-------------------------------------- TUPGBGS_5501_PE1 NOISO QGSTSGQSSGHSQHGSRSGQSS-------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------SYGQHGSRSGQSSRGERHGSSSGSSSCYGQH--GSG GORGO1_135_PE28 NOISO -------------------------------G-Y--S----------------R-V--S- HS1_PE4563 NOISO ------------------------SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQH--GSG HS1_PE4568 NOISO -------------------------------G-P--S----------------G-V--S- LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 HSVA---EHRQSSFESGAGRHRGSSVSQASDSEGQSED--------------SQRQSGSA MOUSE3_PE1152 NOISO -SVI---P---------------------------------------------QRHSGS- MOUSE3_PE1159 ISOFORMIN GRSTSRESSTSQRYGSGSGGS--SGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQH----- MOUSE3_PE1160 ENSMUSG00000041991 GRSTSRESSTSQRYGSGSGGS--SGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQH----- MOUSE3_PE1161 ISOFORMIN GRSTSRESSTSQRYGSGSGGS--SGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQH----- OCHPR19810_PE1 NOISO ----------------------------PSS-SG--------QYSSGSGQCYGSEQCGSA PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO ------------------------SYGQHGSRSGQSSRGERHGSSSGSSSSYGEH--GSG TUPGB77060_PE1 NOISO ------------------------ACGKPRS-------------GSG-----SGS--GSG TUPGBGS_5501_PE1 NOISO ------------------------ACGKPRS-------------GSG-----SGS--GSG MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO SCQSSGHGRQGSGSGQSPSPS--------------------------HGQHG-------- GORGO1_135_PE28 NOISO -----H--T-H--S-G--H-T-H-G--Q-A-R-----------S-Q--H-G--------- HS1_PE4563 NOISO SRQSLGHGQHGSGSGQSPSPS--------------------------RGRHGSGSGQSSS HS1_PE4568 NOISO -----H--T-H--S-G--H-T-H-G--Q-A-G-----------S-H--Y-P--------- LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 -----SGHHHGSNRGQSRDSSRHSGYHQGHQAD----------APHSHSAHG-------- MOUSE3_PE1152 NOISO ------GHSHGQGQVHAEH----------------------------------------- MOUSE3_PE1159 ISOFORMIN ----QSGSRHGSGSGQFPISG-QQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSG MOUSE3_PE1160 ENSMUSG00000041991 ----QSGSRHGSGSGQFPISG-QQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSG MOUSE3_PE1161 ISOFORMIN ----QSGSRHGSGSGQFPISG-QQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSG OCHPR19810_PE1 NOISO SCPSSSAGQYGSGS--YPSS---------------------------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO SCQSSGHGRQGSVSGQSPSPS--------------------------RGRHGSGSGQSSS TUPGB77060_PE1 NOISO SGQSSGRGRHGSGSGRSPSPG----------------------------HHGSGSGQSTG TUPGBGS_5501_PE1 NOISO SGQSSGRGRHGSSSGRSPSPG----------------------------HHGSGSGQSTG MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO YGPYGSGSGWSSSRGPYESGSGHSSGLG--------HRESRSGQSSGYGQHGSSSGHSST HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 ---------HTDSTT----------RGG--------------RQGPSYGHSADSSRHSGS MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN LGQYGS------------------------------------------------------ MOUSE3_PE1160 ENSMUSG00000041991 LGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSST MOUSE3_PE1161 ISOFORMIN LGQYGS------------------------------------------------------ OCHPR19810_PE1 NOISO SGQYISGSSQCSSSQQYMSGKEDGNRCR--------HSNCSEGQRQG------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO YGPHGSGSGRSSSRGPYESGSGHSSGLG--------QQESCSGQSSCYGQHGSSSGYSST TUPGB77060_PE1 NOISO LD-----------------------------------------------RHGSGSGHSSS TUPGBGS_5501_PE1 NOISO LD-----------------------------------------------RHGSGSGHSSS MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO HGQHGSASGQSS-------------------------SCGQHGA-SSGQSSSHGQHGSGS HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 R------QGETS-------------------------VHGQSRSSTRGRQESHQEHSADS MOUSE3_PE1152 NOISO ------------------------------------------------------------ MOUSE3_PE1159 ISOFORMIN ------------------------------------------------------------ MOUSE3_PE1160 ENSMUSG00000041991 QSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCC MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO HGQHGSTSGQSP-------------------------SYGQHGA-SSGQSSSHGQHGSGS TUPGB77060_PE1 NOISO SSQHGSRSGQSS-------------------------TYGHKGGSGSGQSSGYGQHGSGS TUPGBGS_5501_PE1 NOISO SSQHGSRSGESS-------------------------TYGHKGGSGSGQSSGYGQHGSGS MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO -----------------------SGSRQSSSYGR-HGSGSGRSSSSGQHGSGLGESSGFG GORGO1_135_PE28 NOISO ----------------------------------------------------ESESIVHE HS1_PE4563 NOISO SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR-HGSGSGRSSSSGQHGPGLGESSGFG HS1_PE4568 NOISO ----------------------------------------------------ESGSSVHE LOXAF11_42_PE2 ISOFORMIN ---------------------------------------------------------RGH LOXAF11_42_PE3 ENSLAFG00000023048 SRRSGP-------GHARPSSESGAGRHRGSSVSQASDSEGQSEDSH-----RQSGSASGH MOUSE3_PE1152 NOISO ----------------------------------------------------QQRESVHG MOUSE3_PE1159 ISOFORMIN ------------------------------------------------------------ MOUSE3_PE1160 ENSMUSG00000041991 GQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGT-HNSGGSPSSSQRGHGSRSGRSSGLG MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ----GYR------------------------YQR-RGG---------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR-HGSGSGRSSSSGQHGSGLGESSGFG TUPGB77060_PE1 NOISO GQSSGLGRHHSGSGESSGTGEYGSGSGQSSSYG--------------------------- TUPGBGS_5501_PE1 NOISO GQSSGLGRHHSGSGESSGTGEYGSGSGQSSSYG--------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO -------------QQR-SNLGQSSSYGQHGS----------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO HHESSSEQSSSYS----------------------------------------------- GORGO1_135_PE28 NOISO RHGTIHGQTGDTTRHAHSGHGQST--------------------------QTGS------ HS1_PE4563 NOISO HHESSSGQSSSYSQHG-SGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSR HS1_PE4568 NOISO RHGTTHGQTADTTRHGHSGHGQST--------------------------QRGS------ LOXAF11_42_PE2 ISOFORMIN HHGSNHGQSR-------------------------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 HHGSNHGQSR-------------------------------------------------- MOUSE3_PE1152 NOISO QRGRPQGPSQDSSRQPQAGQGQPS--------------------------QSGS------ MOUSE3_PE1159 ISOFORMIN ----PSGQTSSSTRQG-SGQGQASGSGRYGASSGQ-----TSGCGSGQSTRYGEQGSGSR MOUSE3_PE1160 ENSMUSG00000041991 QYGSPSGQTSSSTRQG-SGQGQASGSGRYGASSGQ-----TSGCGSGQSTRYGEQGSGSR MOUSE3_PE1161 ISOFORMIN ----PSGQTSSSTRQG-SGQGQASGSGRYGASSGQ-----TSGCGSGQSTRYGEQGSGSR OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO -----------------GSGHQST--------------------------QRGS------ PANTR1_137_PE9 NOISO HHESSSGQSSSYSQHR-SGSGHSSGYGQHGSRSGQSSRCERHGSSSGSSSRYGQHGSGSR TUPGB77060_PE1 NOISO HHGSTWGQSSGCEQSG-SSSGRSSGYGHQESGSGHSSRQGRHRSSSGSSSSYGQHGSHSG TUPGBGS_5501_PE1 NOISO HHGSTWGQSSGCEQSG-SSSGRSSGYGHQESGSGHSSRQGRHRSSSGSSSSYGQYGSHSA MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO --------RTTGRRSSGHSEYSDSEGHS-------------------------------- HS1_PE4563 NOISO QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH HS1_PE4568 NOISO --------RTTGRRASGHSEYSDSEGHS-------------------------------- LOXAF11_42_PE2 ISOFORMIN ----------------------DSSRHS-------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 ----------------------DSSRHS-------------------------------- MOUSE3_PE1152 NOISO --------RRSPRRSPVHPESSEGEEHS-------------------------------- MOUSE3_PE1159 ISOFORMIN NSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTS----- MOUSE3_PE1160 ENSMUSG00000041991 NSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTS----- MOUSE3_PE1161 ISOFORMIN NSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTS----- OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --------RTIGRRASGHSEYSDSEGHS-------------------------------- PANTR1_137_PE9 NOISO QSSGHGQHGSGSG----------------------------------------------- TUPGB77060_PE1 NOISO QA-SHGQHGSESRQSSRHSKHGSQSGQC--------------------------TLFKQG TUPGBGS_5501_PE1 NOISO QSSGHGQHRSESRQSSRHSKHGSQS----------------------------------G MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO --SQYSSSQYSQYS----------------------------------GHSRHRSGSSQS CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO --------GFSQRPHSR----------------------------------GHTHS---- HS1_PE4563 NOISO ESGSGHSSAYSQHGSGSGHFCSQGQHGST-SGQSSTFDQEGSSTGQSSSHGQHGSGSSQS HS1_PE4568 NOISO --------GVSHT--HS----------------------------------GHAHG---- LOXAF11_42_PE2 ISOFORMIN --------GYHQGHRAD-------------------------------------GP---- LOXAF11_42_PE3 ENSLAFG00000023048 --------GYHQGHRAD-------------------------------------GP---- MOUSE3_PE1152 NOISO --------VVPQRHSGS----------------------------------SHGHG---- MOUSE3_PE1159 ISOFORMIN -------------------------------------------------------GRSQH MOUSE3_PE1160 ENSMUSG00000041991 -------------------------------------------------------GRSQH MOUSE3_PE1161 ISOFORMIN -------------------------------------------------------GRSQH OCHPR19810_PE1 NOISO -----------SYCEGESRFVSSTPFYEYVQEL-RTFGQ--------------------- PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --------GVSHT--HS----------------------------------GHAHG---- PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO S-DCGLENTY----AFSHKFCSSSPLYLYIHEQRRSFQT--------------------- TUPGBGS_5501_PE1 NOISO S-DCGLENIY----AFSHKFCSSSPLYLYIHEQRRSFQT--------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO S----------------------------------------GHSRHGSGSSQSSSCGQHG CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO -----------------QAGSQHGE----------------------------------- HS1_PE4563 NOISO SSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS-SSGRHGSGSGQSSGFGHHE HS1_PE4568 NOISO -----------------QAGSQHGE----------------------------------- LOXAF11_42_PE2 ISOFORMIN -----------------QSHPAHGH----------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 -----------------QSHPAHGH----------------------------------- MOUSE3_PE1152 NOISO -----------------QGQGQAGHQ---------------------------------- MOUSE3_PE1159 ISOFORMIN QSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYG MOUSE3_PE1160 ENSMUSG00000041991 QSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYG MOUSE3_PE1161 ISOFORMIN QSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYG OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO -----------------QAGSQHGE----------------------------------- PANTR1_137_PE9 NOISO ------------QPSRGRHGSGSGQSSSYGPYGSASGWSS-SRGHYESGSGQSSGFGHHE TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO FSSRESSGFGQHGSGLGQSSSYGQHGSTSGQSSSCGQQ-RSNLGQSSSYGQHGSSQYGSS CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ----------QHGSGSGHSSSYGQHGSRSGQSSRGERH-GSSSGSSSSYGQHGSGSRQ-- GORGO1_135_PE28 NOISO ----------------SESAIHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRR--- HS1_PE4563 NOISO SSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERH-GSSSGSSSSYGQHGSGSRQ-- HS1_PE4568 NOISO ----------------SGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRR--- LOXAF11_42_PE2 ISOFORMIN ----------------SDSTARGRQGSSHGQSVDSSRHSDSQQGETSARGQYRSSTRDRQ LOXAF11_42_PE3 ENSLAFG00000023048 ----------------SDSTARGRQGSSHGQSVDSSRHSDSQQGETSARGQYRSSTRDRQ MOUSE3_PE1152 NOISO ----------------QRESVHGQRGRPQGPSQDSSRQPQAGQGQPSQSGSGRSPGRSPV MOUSE3_PE1159 ISOFORMIN STSGQTASSTRQGSGQGQASGSGRCGAS-----SGQTS-GCGSGQSTRYGEQGSGSRN-- MOUSE3_PE1160 ENSMUSG00000041991 STSGQTASSTRQGSGQGQASGSGRCGAS-----SGQTS-GCGSGQSTRYGEQGSGSRN-- MOUSE3_PE1161 ISOFORMIN STSGQTASSTRQGSGQGQASGSGRCGAS-----SGQTS-GCGSG---------------- OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ----------------SGSSVHERHGTTHGQTGDTTRHAHSGLGQSTQRGSRTAGRR--- PANTR1_137_PE9 NOISO SSSGQSSSYSQHRSGSGHSSGYGQHGSRSGQSSRGERH-GSSSGSSSRYGQHGSGSRQ-- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO QSYS----HSRHRSGS-------------------------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO -SSG----HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPHESG----------------- GORGO1_135_PE28 NOISO --------------GSGHSESSDSEV---------------------------------- HS1_PE4563 NOISO -SLG----HGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG----------------- HS1_PE4568 NOISO --------------GSGHSESSDSEV---------------------------------- LOXAF11_42_PE2 ISOFORMIN ESHQDHSADQSRYSGAGNTQASDSEG---------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 ESHQDHSADQSRYSGAGNT----------------------------------------- MOUSE3_PE1152 NOISO -----------------HPESSEGEE---------------------------------- MOUSE3_PE1159 ISOFORMIN -SST----QSRGRSTS--RESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQT MOUSE3_PE1160 ENSMUSG00000041991 -SST----QSRGRSTS--RESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQT MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --------------GSGHSESSDSEV---------------------------------- PANTR1_137_PE9 NOISO -SSG----HGQHGSGSGQSPSPSRGRHVSGSGQSSSYGPHGSG----------------- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ----------SQSSGHSQQGLGSGQ--SSSFGQHGSSSRESSGFGQHSSGLGQSSSYGQH CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ---------SGRSSGRGPYESGSGH--SSGLGQQESHSGQSSGYGQHGSSSGHSSTHGQH GORGO1_135_PE28 NOISO ------------HSG-----VSHTH-SGHTYGQARSQ----------------------H HS1_PE4563 NOISO ---------SGWSSSRGPYESGSGH--SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH HS1_PE4568 NOISO ------------HSG-----VSHTH-SGHTYGQARSQ----------------------H LOXAF11_42_PE2 ISOFORMIN -----QSENSQKQSG-----YSSTHYHGSTHGQSRDNSRHSGSLQEHRADG-------PL LOXAF11_42_PE3 ENSLAFG00000023048 ----------QKQSG-----YSSTHYHGSTHGQSRDNSRHSGSLQEHRADG-------PL MOUSE3_PE1152 NOISO -----HSVVPQRHSG-----SGHGH--GQGQGQAGHQ----------------------- MOUSE3_PE1159 ISOFORMIN EGSQQHGSCCGQSSGYGQNEYGSGH--SASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGH MOUSE3_PE1160 ENSMUSG00000041991 EGSQQHGSCCGQSSGYGQNEYGSGH--SASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGH MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------HSG-----VSHTH-SGHTYGQARSQ----------------------H PANTR1_137_PE9 NOISO ---------SGRSSSRGTYESGSGH--SSGLGQQESCSGQSSGYGQHGSSSGHSSTHGQH TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO GSTSGQSSSCGQQGSNLGQSSSYGQHGSSQYGSS-------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO GSTSGQSLSCGQHGASSGQSSSHGQHGCGSSQSSGYGRQGSGS--------GQSPGYGQH GORGO1_135_PE28 NOISO --GESGSAIHGRQGTIHGQTGDTTRHGQS------------GHGQSTQTGS---RTTGRQ HS1_PE4563 NOISO GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS--------GQSPGHGQR HS1_PE4568 NOISO --GESGSAIHGRQGTIHGQTGDTTRHGQS------------GHGQSTQTGS---RTTGRQ LOXAF11_42_PE2 ISOFORMIN --SHSDSSARGRQGSSHGQSVDSSRHSGS------------HQGETSAHGESRSSTRGRQ LOXAF11_42_PE3 ENSLAFG00000023048 --SHSDSSARGRQGSSHGQSVDSSRHSGS------------HQGETSAHGESRSSTRGRQ MOUSE3_PE1152 NOISO ----QRESVHGQRGRPQGPSQDSSRQPQA------------GQGQPSQSGSGRSPRRSP- MOUSE3_PE1159 ISOFORMIN GSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQ MOUSE3_PE1160 ENSMUSG00000041991 GSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQ MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --RESGSAIHGRQGTIHGQTGDTTRHGQS------------GHGQSTQTGS---RTTGRQ PANTR1_137_PE9 NOISO GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGQQGSGS--------GQSPSRGRH TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO -----QSYSHSRHR---------------------------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO GSGSRQSPSYG------------------------------------------------- GORGO1_135_PE28 NOISO RSSHSESSDSEVHSETS------------------------------------------- HS1_PE4563 NOISO GSGSRQSPSYG------------------------------------------------- HS1_PE4568 NOISO RSSHSESSDSEVHSEAS------------------------------------------- LOXAF11_42_PE2 ISOFORMIN ETQQEHSAEHSRHSVAEH------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 ETQQEHSAEHSRHSVAEHVQSSHESEAGRHRG--SSVRQASD------------------ MOUSE3_PE1152 NOISO --VHPESSEGEEHSVVPQRHSGS----GHGHG--QG------------------------ MOUSE3_PE1159 ISOFORMIN GSGSRNSSTQSRGRSTSRES-STSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQT MOUSE3_PE1160 ENSMUSG00000041991 GSGSRNSSTQSRGRSTSRES-STSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQT MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO RSSHSQASDSEVHSEAS------------------------------------------- PANTR1_137_PE9 NOISO GSGSEHSSSYG------------------------------------------------- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SGSSQSSGHSRHGSGSGRS---SSFGQRGSSSRE--------------SSGFGQHGPGLG CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ----------RHG----------------------------------------------- GORGO1_135_PE28 NOISO ---PTNSGHPHSQA---------------------------------------GSRHGQS HS1_PE4563 NOISO ----------RHGSGSGRS---SSSGQ---------------------------HGSGLG HS1_PE4568 NOISO ---PTHSGHTHSQA---------------------------------------GSRHGQS LOXAF11_42_PE2 ISOFORMIN ---EGQSEHSRSQSGSASRQDRSTYSQSRDSSRHSGSHQGHRAEAP-----QSHSAHGHS LOXAF11_42_PE3 ENSLAFG00000023048 --QEGQSEHSRSQSGSASRQDRSTYSQSRDSSRHSGSHQGHRAEAP-----QSHSAHGHS MOUSE3_PE1152 NOISO ---QGQAGH-------------------------------------------------QQ MOUSE3_PE1159 ISOFORMIN SGRSQHQSGSRHGSGSGQF---PISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSE MOUSE3_PE1160 ENSMUSG00000041991 SGRSQHQSGSRHGSGSGQF---PISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSE MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ---PTHSGHTHSQA---------------------------------------GSRHGQS PANTR1_137_PE9 NOISO ----------QHGSGSSWS---SSNGP---------------------------HGSGSG TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO QSSSYGQHGSTSGQSSSCSQQ-GSNLGQSSSYGQCGSSQ--------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO GSSGHGRQGTTHGQT--------------------------------------------- HS1_PE4563 NOISO ESSGFGHHESSSGQSSSYSQH-GSGSGHSSGYGQHGSRS--------------------- HS1_PE4568 NOISO GSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSE----SSDSEVHSWG LOXAF11_42_PE2 ISOFORMIN YSTAIGTQDSSQGQSFDSSRHSGSHHGEASARGELRSSSRG------------------- LOXAF11_42_PE3 ENSLAFG00000023048 YSTAIGTQDSSQGQSFDSSRHSGSHHGEASARGELRSSSRGRQESH----QEHSADRSRH MOUSE3_PE1152 NOISO RESVHGQRGRPQGPSQDSSRQPQAGQGQPSQSSSGRSPRRSPVHPESSEGEEHSVVPQRH MOUSE3_PE1159 ISOFORMIN QSSGLGHYGSTSGQTASSTRQ-GSGQGQASGSGRCGASS--------------------- MOUSE3_PE1160 ENSMUSG00000041991 QSSGLGHYGSTSGQTASSTRQ-GSGQGQASGSGRCGASS--------------------- MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO GSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSE----SSDSEVHSWG PANTR1_137_PE9 NOISO QSSGFGHHESGSGQSSGYGQH-GSSSGHSSTHGQHGSTS--------------------- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ---------Y-------------------------------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ---------GQ---------------SSRGERHGSSSGSSSHY-GQHGSGSRQSSGHGRQ HS1_PE4568 NOISO --------------------SHTHSGHIQGQ-----AGSQQR---QPGSTVHGRLETTHG LOXAF11_42_PE2 ISOFORMIN ---------------RERASSVSQASDIEGQSEGS-VGQSTSYHGSSGFGSRNQPGSIHG LOXAF11_42_PE3 ENSLAFG00000023048 SGTGHGRSSFESGTGRERASSVSQASDIEGQSEGS-VGQSTSYHGSSGFGSRNQPGSIHG MOUSE3_PE1152 NOISO SGSGHGHG----------------------QGQGQ-AG-------------HQQRESLHG MOUSE3_PE1159 ISOFORMIN ---------G--------------------QTSGCGSGQSTRY-GEQGSGSRNSSTQSRG MOUSE3_PE1160 ENSMUSG00000041991 ---------G--------------------QTSGCGSGQSTRY-GEQGSGSRNSSTQSRG MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO --------------------SHTHSGHIQGQ-----AGSQQR---QPGSTVHGRLETTHG PANTR1_137_PE9 NOISO ---------GQ---------------SSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGQQ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ------------------------------------------------------------ CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ---------------------------SGSGRSSSRGPYKSRSGHSSVFGQHESGSGHSS GORGO1_135_PE28 NOISO --GDTTRHGH-----------------SSYG-QSTQTGSR----------SSRTSHFQSH HS1_PE4563 NOISO GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSS HS1_PE4568 NOISO QTGDTTRHGH-----------------SGYG-QSTQTGSR----------SSRASHFQSH LOXAF11_42_PE2 ISOFORMIN QSGDSLRHSG-----------------LHSG---QISTQR----------QSDSTHFYSV LOXAF11_42_PE3 ENSLAFG00000023048 QSGDSLRHSG-----------------LHSG---QISTQR----------QSDSTHVHQS MOUSE3_PE1152 NOISO QRGRSQSPFHPSHS-------------IHWQSKCTISKKSSRLSG-----HYGRNHFQST MOUSE3_PE1159 ISOFORMIN RST-------------------------------------SR--ESSCSQHDVSGSGESS MOUSE3_PE1160 ENSMUSG00000041991 RST-------------------------------------SR--ESSCSQHDVSGSGESS MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO QTGDTTRHGH-----------------SGYG-QSTQTGSR----------SSRTSHFQSH PANTR1_137_PE9 NOISO GSGSGQPPSHDRHWSGSGHSSSYGQHGSGSGRSSSHGPYESRSGHSSVFGQHESGSGHSS TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO ---------------------------------------GSSQSSGCRQHGSVSGQSSSF CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO AYSQHGSGSGHFCSQG--------------------------------QHGSTSGQSSTF GORGO1_135_PE28 NOISO SSERQRHGSSQVWKHGSYGP-----------------------------------AEYDY HS1_PE4563 NOISO AYSQHGSGSGHFCSQG--------------------------------QHGSTSGQSSTF HS1_PE4568 NOISO SSERQRHGSSQVWKHGSYGP-----------------------------------AEYDY LOXAF11_42_PE2 ISOFORMIN NNDRQRHDAGHCWRHGSYGS-----------------------------------SDYDY LOXAF11_42_PE3 ENSLAFG00000023048 QKADHG------------------------------------------------------ MOUSE3_PE1152 NOISO -ISGNQYDSSQSSRHGSYGP-----------------------------------QDYDY MOUSE3_PE1159 ISOFORMIN SFSQHRSCQSQASHNGQCGPFSGQSSGHIQHGPCFGQTEGSFQSSNCGQQGTTSYQSSGF MOUSE3_PE1160 ENSMUSG00000041991 SFSQHRSCQSQASHNGQCGPFSGQSSGHIQHGPCFGQTEGSFQSSNCGQQGTTSYQSSGF MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO SSERQRHGSSQVWKHGSYGP-----------------------------------AEYDY PANTR1_137_PE9 NOISO AYSQHGSGSEHFCSQG--------------------------------QHGSASGQSSTF TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO GQHGSSSRESSGFGQHGSG---LG-QSSTYG-HHGSTSGQSSSCGQNIS----------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO DQE-------------GSS---T------------------------------------- GORGO1_135_PE28 NOISO GHT--------GYGPSGGSRKSISNSHLSWSIDST-ANKQLSRH---------------- HS1_PE4563 NOISO DQE-------------GSS---T------------------------------------- HS1_PE4568 NOISO GHT--------GYGPSGGSRKSISNSHLSWSTDST-ANKQLSRH---------------- LOXAF11_42_PE2 ISOFORMIN GQS--------GFGQS-------------------------------------------- LOXAF11_42_PE3 ENSLAFG00000023048 ------------------------------------------------------------ MOUSE3_PE1152 NOISO GQS--------GYGPSGRLRSNSQSS-IPFSSAHRATNMEVLPCGQSFSPSDHVGTKANE MOUSE3_PE1159 ISOFORMIN DQQ-------------RSG---LH-QSFPCS-NHESTSQEYSSFGSCVSGSGECSGFGNQ MOUSE3_PE1160 ENSMUSG00000041991 DQQ-------------RSG---LH-QSFPCS-NHESTSQEYSSFGSCVSGSGECSGFGNQ MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO GHT--------GYGPSGGSRKSISNSHLSWSIDST-ANKQLSRH---------------- PANTR1_137_PE9 NOISO DQE-------------GSS---T------------------------------------- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO -GSGQSSSYGQCGSGSDQSSRYSQQRSGLGQSSGHVQCGTGPSQSSSCSQFGSGWSQSSS CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ---GQSSSYGHHGSGSSQSSGYGQHRAGSGQSLSHGRHRSGSGQSSSYGQHGSGSGQASG GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ---GQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSG HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 ------------------------------------------------------------ MOUSE3_PE1152 NOISO QIGELVFKYRESETGPDQSVDYYNLTESNSTT-RGHECS--------------------- MOUSE3_PE1159 ISOFORMIN VSRPSQSTYEHHESNRNQSSGYRQYNTASGQSYCGGQCGSNSNQSSSYREQGLGSNQSSQ MOUSE3_PE1160 ENSMUSG00000041991 VSRPSQSTYEHHESNRNQSSGYRQYNTASGQSYCGGQCGSNSNQSSSYREQGLGSNQSSQ MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO ---GQSSSYGHRGSGSSQSSGYGQHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSG TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO YGQHRSGSGQCSTQ---------------------------SQHGSGLGQCSTSEQHGPG CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO YSQHGSGSGQDG-----YSYCKGGSNHEGGSSGSY------------------------- GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO YSQHGSGSGQDG-----YSYCKGGSNHDGGSSGSY------------------------- HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 ------------------------------------------------------------ MOUSE3_PE1152 NOISO -------HGHSVVVPEHSDD--SDFNYGH----SYNGKQQICQSQPTVQSCFDDSQYILF MOUSE3_PE1159 ISOFORMIN YGQYRCPSSHYSSQSQHGVGCSHGFNTGQYGSGSYP-SSNSRQNCPGSGLCPTSEQYGSG MOUSE3_PE1160 ENSMUSG00000041991 YGQYRCPSSHYSSQSQHGVGCSHGFNTGQYGSGSYP-SSNSRQNCPGSGLCPTSEQYGSG MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO YSQHGSGSGQDG-----YSYCKGGGNHEGGSSGSY------------------------- TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SCHSSSSEQCGSGSGQCSSYDQYEL----------------------------------- CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ------------------------------------------------------------ HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 ------------------------------------------------------------ MOUSE3_PE1152 NOISO QKHL-----ESPSFGNQSGFSPNERQLYTCNESIDSYHLSSDSNNRNQIYSSNNSFPNLY MOUSE3_PE1159 ISOFORMIN SCQSFSPGSCGSGYGQYSNFEQPQS-NRRCGNQWESGCSSSNCNENQSIRVH-RQVE--- MOUSE3_PE1160 ENSMUSG00000041991 SCQSFSPGSCGSGYGQYSNFEQPQS-NRRCGNQWESGCSSSNCNENQSIRVH-RQVE--- MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO -----------------------------------QDNRQGGYYYQ-REGGHDGGRDTNS CALJA18_7_PE23 ENSCJAG00000006405 ------------------------------------------------------------ GORGO1_135_PE25 NOISO ------------------------------------------------------------ GORGO1_135_PE28 NOISO ------------------------------------------------------------ HS1_PE4563 NOISO ------------------------------------------------------------ HS1_PE4568 NOISO ------------------------------------------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------------------------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 ------------------------------------------------------------ MOUSE3_PE1152 NOISO CIGTEQCIYLPSATILGEGTEGQEPGYTQPGTICKYNQFLDGRKS--RTRGNHETGKMKS MOUSE3_PE1159 ISOFORMIN --TSSGCGFGQFSS-----QEQIRSDTTGKLSLCNVDNRQGNCKYQIIKGSNFGMRNTVS MOUSE3_PE1160 ENSMUSG00000041991 --TSSGCGFGQFSS-----QEQIRSDTTGKLSLCNVDNRQGNCKYQIIKGSNFGMRNTVS MOUSE3_PE1161 ISOFORMIN ------------------------------------------------------------ OCHPR19810_PE1 NOISO ------------------------------------------------------------ PANTR1_137_PE12 ENSPTRG00000001312 ------------------------------------------------------------ PANTR1_137_PE16 NOISO ------------------------------------------------------------ PANTR1_137_PE9 NOISO ------------------------------------------------------------ TUPGB77060_PE1 NOISO ------------------------------------------------------------ TUPGBGS_5501_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

BOVIN3_21_PE4 NOISO SFYKLRTSTPLYEYVQEQRC---- CALJA18_7_PE23 ENSCJAG00000006405 -----------LGFSESQRYYFYE GORGO1_135_PE25 NOISO -FLSFPSSTSPYEYVQEQRCYFYQ GORGO1_135_PE28 NOISO ------------------------ HS1_PE4563 NOISO -FLSFPSSTSPYEYVQEQRCYFYQ HS1_PE4568 NOISO ------------------------ LOXAF11_42_PE2 ISOFORMIN ------------------------ LOXAF11_42_PE3 ENSLAFG00000023048 ------------------------ MOUSE3_PE1152 NOISO GSAYLDSNTPLYTYVQEQKSYYFE MOUSE3_PE1159 ISOFORMIN GPHSFNSSTPLYEYVQEQRR---- MOUSE3_PE1160 ENSMUSG00000041991 GPHSFNSSTPLYEYVQEQRR---- MOUSE3_PE1161 ISOFORMIN ------------------------ OCHPR19810_PE1 NOISO ------------------------ PANTR1_137_PE12 ENSPTRG00000001312 -----------LGFSQSQRYYYYE PANTR1_137_PE16 NOISO ------------------------ PANTR1_137_PE9 NOISO -FLSFPSSTSPYEYVQEQRCYFYQ TUPGB77060_PE1 NOISO ------------------------ TUPGBGS_5501_PE1 NOISO ------------------------ MATCH CONSENSUS ????????????????????????


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