Alignment of the gene Family HOG000112647 of HOGENOM

JalView . Download . SRS . Tree .
Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL192926_1_1_PE8 NOISO -----------------------------SHVMQEE------SANAMEWEQLPAETLRQV BOVINUN_004_136_PE2 NOISO -----------------------------SHVMQEE------NANDMECEQLPAETLRQV CALJAX_98_PE17 NOISO ------------------------------------------------------------ CANFAX_86_PE1 NOISO ------------------------------------------------------------ CAVPO46_15_PE1 NOISO QSIISQVLVSGLLAVPGHSSPSGSQEPGAISCMQEE------STNDMECEHLPAEALRQV DANRE14_13_PE1 NOISO -----------------CYPPNKYYVLFLSSVMLED------GQDGMDSDSLTPGLTREV DASNOGS_4069_PE1 NOISO ESLDSRSVQVGLLAATGC--PSCPQEPFSIHVMQEE------STNDMECEELPAETVRQV ERIEUGS_4936_PE1 NOISO ---------------------------------------------------------RQV FUGRU89_1_PE126 NOISO -----------------------------SSAMLEE------SQDGMDSGTLSPASARQV GASACGROUPIV_13_PE18 NOISO ------------------------------------------------------------ GORGOX_108_PE1 NOISO ETLDSQRVQDRLLATPGCSSPSGQQELFSSHVMQEE------SANDMECEQLPAEILRQV HORSEX_87_PE3 ENSECAG00000024553 -----------------------------SHVMQEE------SANDMECEQLPAETLRQV HSX_PE1916 ENSG00000147234 ETLDSQRVQDRLLAAPGCSSPSGQQELFSSHVMQEE------SANDMECEQLPAEILRQV HSX_PE1917 ISOFORMIN ---------------------------------------------------------RQV LOXAF32_25_PE12 ISOFORMIN ------------------------------------------------------------ LOXAF32_25_PE13 ENSLAFG00000017551 ------------------------------------------------------------ MACEUGS_5651_PE1 NOISO ------------------------------------------------------------ MACMUX_108_PE18 NOISO ---------------------------------------------------------RQV MICMUGS_2482_PE1 NOISO ---------------------------------------------------------RQV MOUSEX_PE1762 ENSMUSG00000042425 ------------------------------------------------------------ OCHPRGS_2823_PE1 NOISO ---------------MKCTSISGPEP-FPXXXXXXXXXX------XXXXXXXXXXXXXXX ORYLA10_15_PE17 NOISO ---------------------------------------------------------RQV PANTRX_107_PE19 NOISO -----------MLAAPGCSSPSGQQELFSSHVMQEE------SANDMECEQLPAEILRQV PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO -----------------------------SHVMPEE-----RGGDDMECGQLPSDTLRQV PROCAGS_4183_PE1 NOISO --------GKALASLRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_2099_PE1 NOISO METNNQRVQARLLVATGGNSPSCPQEPFSSNVMQEE------STNDMECEQLPAETLRQV RABITX_58_PE1 NOISO -----------------------------SHVMQEE------SANDMECEQLPAETLRHV SORARGS_4009_PE1 NOISO ------------------------------------------------------------ SPETRGS_3185_PE1 NOISO ---------------------------------------------------------HQV TURTRGS_1847_PE1 NOISO -----------LPAATGGSSPSCPWEPLSSHVIQEE------SANDMECEQLPAETLRQV XENTR615_PE6 NOISO ---------------------------------------------------------RQV MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192926_1_1_PE8 NOISO TIHRDPIYGFGFVAGSERPMVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL BOVINUN_004_136_PE2 NOISO TIHRDPICGFGFVAGSERPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL CALJAX_98_PE17 NOISO ------------------------------------------------------------ CANFAX_86_PE1 NOISO ------------------------------------------------------------ CAVPO46_15_PE1 NOISO TIHRDPLYGFGFVAGSERPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL DANRE14_13_PE1 NOISO CIQRHPSHGFGFIAGSERPVVVRSVSADGPSSGKLYPGDQILAINQELVSDVPREKVIDL DASNOGS_4069_PE1 NOISO TIHRDPICDFGFVAGSEKPVV-RSVRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ERIEUGS_4936_PE1 NOISO TIHRDPIYGFGFVAGSERPVVVRSVRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX FUGRU89_1_PE126 NOISO AIQRHPTQGFGFVAGSQRPVIVRSVSADGPSFGKLLPGDQILAINEETVSDAPRERVIDL GASACGROUPIV_13_PE18 NOISO ------------------------------------------------------------ GORGOX_108_PE1 NOISO TVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIEL HORSEX_87_PE3 ENSECAG00000024553 TIHRDPIYGFGFVAGSERPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL HSX_PE1916 ENSG00000147234 TVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIEL HSX_PE1917 ISOFORMIN TVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIEL LOXAF32_25_PE12 ISOFORMIN ------------------------------------------------------------ LOXAF32_25_PE13 ENSLAFG00000017551 ------------------------------------------------------------ MACEUGS_5651_PE1 NOISO ------------------------------------------------------------ MACMUX_108_PE18 NOISO TVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIEL MICMUGS_2482_PE1 NOISO TIHRDPIYGFGFVAGSEKPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL MOUSEX_PE1762 ENSMUSG00000042425 ------------------------------------------------------------ OCHPRGS_2823_PE1 NOISO XXXXXXIYGFGFVAGSERPVVVRSVRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ORYLA10_15_PE17 NOISO TIQRHPTQGFGFIAGSQRPVIVRSVFADGPSFGKLLPGDQILAINEETVSDAPRERVIDL PANTRX_107_PE19 NOISO TVHRDPIYGFGFVAGSERPVVVRSVRPS-------------------------------- PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO TVQRHPLYGFGFVAGSERPVVVRSVAAGGPSEDKLLPRDQILAINDDDVSESPQIEEGTL PROCAGS_4183_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXGPSENRLPAGDQIV-INEEDRSEDPRERFIEL PTEVAGS_2099_PE1 NOISO TIHRDPIYGFGFVAGSERPVVVRSVRSGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEH RABITX_58_PE1 NOISO TIHRDPIYGFGFVAGSERPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL SORARGS_4009_PE1 NOISO ------------------------------------------------------------ SPETRGS_3185_PE1 NOISO TIHRDPIYGFGFVAGSERPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL TURTRGS_1847_PE1 NOISO TIHRDPIYGFGFVAGSERPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIEL XENTR615_PE6 NOISO TIIRRPGAGFGFVAGSARPVVVRSVIAGGPSENKLLAGDQILAINQEDVSEASRERFIEL MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192926_1_1_PE8 NOISO IRSAKEFIVLTVLHTHQSPKSAFISAAKKARLRSNPAKVRFSEQVAVGETDAKML-KK-- BOVINUN_004_136_PE2 NOISO IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- CALJAX_98_PE17 NOISO ------------------------------------------------------------ CANFAX_86_PE1 NOISO ------------MFFFQSPKSAFISAAKKARLRWNPAKVRFSEQVAVGDTDAKMM-KK-- CAVPO46_15_PE1 NOISO IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETHAKMM-KK-- DANRE14_13_PE1 NOISO VRCCRDSIVLTVLQPQQSPKSAFISAAKKARLRTNPPKVRFSEQVSISDPDSTMLK-D-- DASNOGS_4069_PE1 NOISO XXXXXXXXXXXXXXXXXSPKSAFISAAKKARLRSNPVKVRFSEQVAVGETDAKMM-KK-- ERIEUGS_4936_PE1 NOISO XXSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- FUGRU89_1_PE126 NOISO VRRCKDSIVLTVLQPHQSPKSAFISAAKKAQLRTNPPKVRFSEQVSISDPDPTMLK-D-- GASACGROUPIV_13_PE18 NOISO -------------SYPQSPKSAFISAAKKARLRTNPPKVRFSEQVSISDPDSTMLK-D-- GORGOX_108_PE1 NOISO IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDSKMM-KK-- HORSEX_87_PE3 ENSECAG00000024553 IRSAKEFPMLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- HSX_PE1916 ENSG00000147234 IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- HSX_PE1917 ISOFORMIN IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- LOXAF32_25_PE12 ISOFORMIN ----------------QSPKSAFISAAKKAKLRSKPVKVQFSEQAAFGETDTAKPLSK-- LOXAF32_25_PE13 ENSLAFG00000017551 ------------MFFFQSPKSAFISAAKKAKLRSKPVKVQFSEQAAFGETDTVMM-SR-- MACEUGS_5651_PE1 NOISO -----------------PLESAFISAAKKAERRSSPVKVQFKVT--ASKKDPDML-KK-- MACMUX_108_PE18 NOISO IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- MICMUGS_2482_PE1 NOISO IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSKPVKVRFSEQVAVGQTDAKMM-KK-- MOUSEX_PE1762 ENSMUSG00000042425 ------------MFFFQSPKSAFISAAKKAKLRSNPVKVRFSEQVTIGETDAKMM-KK-- OCHPRGS_2823_PE1 NOISO XXRAKEFIVLTVLHTHQSPKSAFISAAKKAQLRSHPVKVRFSEQVAVGETDAKMM-KK-- ORYLA10_15_PE17 NOISO VRHCKDTIVLTVLQPHQSPKSAFISAAKKARLRTNPPKVRFSEQVSISDPDSTMLK-D-- PANTRX_107_PE19 NOISO ---AKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO CASRAGWVIYPV-LSFQSPKSAFISAAKKAKLRSNPAKVRFSEQVTVGETDPDML-KK-- PROCAGS_4183_PE1 NOISO IRSA-EFIVLTVLHT-YSPKSAFISATKKAKLRSKPVKAEFSEKVAVGKTDAKMM-KK-- PTEVAGS_2099_PE1 NOISO IXXXXXXXXXXXXXXXXSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMM-KK-- RABITX_58_PE1 NOISO IRSRKLFICLNLLTSTKSPKSAFISAAKKAQLRSHPVKVRFSEQVAVGETDAKMM-KK-- SORARGS_4009_PE1 NOISO -----------------SPKSAFISAAKKAKLRSHPAKVRFSEQVAVGETDAKMM-KK-- SPETRGS_3185_PE1 NOISO IRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGEIDAKMM-KK-- TURTRGS_1847_PE1 NOISO IRNAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAIGETDAKMM-KK-- XENTR615_PE6 NOISO VRNAKESITLTVLHPHQSPKSAFISAAKKEKLRSNPGRVRFSELVTVGEAEADMLKMKDS MATCH CONSENSUS ?????????????????SPKSAFISAAKKA?LR??P?KVRFSEQV?????D??M??????

AILMEGL192926_1_1_PE8 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE BOVINUN_004_136_PE2 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE CALJAX_98_PE17 NOISO ------------------------------------------------------------ CANFAX_86_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRCIEHFALVLEYAGLE CAVPO46_15_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE DANRE14_13_PE1 NOISO DSLLLIPNVLKVFLEN-GQIKSFTFDSRTTVRDVISSLQDRLSLRYIEHFALVLESGGLA DASNOGS_4069_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKXXXXXXXXXXXXXXXXXXXXXXXXXXXX ERIEUGS_4936_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVIITLQDRLSLRYIEHFALVLEYAGPE FUGRU89_1_PE126 NOISO DSLLLIPNVLKVFLEN-GQIKSFTFDSRTTVRDVISSLQDRLSLRYIEHFALVLEAGALD GASACGROUPIV_13_PE18 NOISO DSLLLIPNVLKVFLEN-GQIKSFTFDSRTTVRDVISSLQDRLSLRYIEHFTLVLEAGGLD GORGOX_108_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMLTLQDRLSLRYIEHFALVLEYAGPE HORSEX_87_PE3 ENSECAG00000024553 EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE HSX_PE1916 ENSG00000147234 EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPE HSX_PE1917 ISOFORMIN EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPE LOXAF32_25_PE12 ISOFORMIN EQMALVPGGCKWFALKMQ-IYPYTLRLFSLPQDVMVTLQDRLSLRYIEHFALVLEYAGTE LOXAF32_25_PE13 ENSLAFG00000017551 EALGVVGRRRVVFLRSMGGAAVSLSGLFSLPQDVMVTLQDRLSLRYIEHFALVLEYAGTE MACEUGS_5651_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYASPE MACMUX_108_PE18 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE MICMUGS_2482_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE MOUSEX_PE1762 ENSMUSG00000042425 EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMATLQDRLSLRSIEHFALVLEYTGPE OCHPRGS_2823_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE ORYLA10_15_PE17 NOISO DSLLLIPNVLKVFLEN-GQIKSFTFDSRTTVRDVISSLQDRLSLRYIEHFALVLEAGGLD PANTRX_107_PE19 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVK---------------------------- PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRHIEHFALVLEYSSPE PROCAGS_4183_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_2099_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMMTLQDRLSLRYIEHFALVLEYVGPE RABITX_58_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE SORARGS_4009_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVIVTLQDRLSLRYIEHFALVLEYAGPE SPETRGS_3185_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRYIEHFALVLEYAGPE TURTRGS_1847_PE1 NOISO EALLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRXXXXXXXXXXXXXXX XENTR615_PE6 NOISO PPLLLIPNVLKVFLEN-GQIKSFTFDGRTTVKDVMVTLQDRLSLRHRDHFSLVLEYSATE MATCH CONSENSUS ??LLLIPNVLKVFLEN?GQIKSFTFD?RTTV?DV???LQDRLSLR???HF?LVLE?????

AILMEGL192926_1_1_PE8 NOISO QNHKFLLLQDKQPLAYVVQRTHYQGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND BOVINUN_004_136_PE2 NOISO QNQKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND CALJAX_98_PE17 NOISO ------------------------------------------------------------ CANFAX_86_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYQGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND CAVPO46_15_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND DANRE14_13_PE1 NOISO QNQRLHLLQENQPLSHVVHRTYFQGMKCLFRICFFPKDPSDLLRRDPAAFEYLYIQSRND DASNOGS_4069_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ERIEUGS_4936_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND FUGRU89_1_PE126 NOISO QNQRLHLLQDNQPLTHVVHRTYFQGMKCLFRVCFSPKDPADLLRRDPAAFEYLYIQSRND GASACGROUPIV_13_PE18 NOISO QNQRLHLLQDNQPLTHVVHRTYFQGMKCLFRICFFPKDPADLLRRDPAAFEYLYIQSRND GORGOX_108_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND HORSEX_87_PE3 ENSECAG00000024553 QNHKFLLLQDKQPLAYVVQRTHYQGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND HSX_PE1916 ENSG00000147234 QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND HSX_PE1917 ISOFORMIN QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND LOXAF32_25_PE12 ISOFORMIN QNHKFLLLQDKQPLAYVVQRTHYQGMKCLFRISFFPKDPVELLHRDPAAFEYLYIQSRND LOXAF32_25_PE13 ENSLAFG00000017551 QNHKFLLLQDKQPLAYVVQRTHYQGMKCLFRISFFPKDPVELLHRDPAAFEYLYIQSRND MACEUGS_5651_PE1 NOISO QSHKFLLLQDKQPLAHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRND MACMUX_108_PE18 NOISO QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND MICMUGS_2482_PE1 NOISO QNHKFLLLQDKQPLAYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRND MOUSEX_PE1762 ENSMUSG00000042425 QNHKFLILQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND OCHPRGS_2823_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRSD ORYLA10_15_PE17 NOISO QNQKLNLLQDNQPLTHVVHRTYFQGMKCLFRICYFPKDPADLLRRDPAAFEYLYIQSRND PANTRX_107_PE19 NOISO ----------------VVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO QSHRFLLLQDKQPLAHVVQRTHYHGMRCLFRVSFFPKDPVELLRRDPAAFEYLYIQSRND PROCAGS_4183_PE1 NOISO XXXXXXXXXXXXXXXXVVQRTHYQGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND PTEVAGS_2099_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYQGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQXXXX RABITX_58_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND SORARGS_4009_PE1 NOISO QNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND SPETRGS_3185_PE1 NOISO QSHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQXXXX TURTRGS_1847_PE1 NOISO XXXXXXXXXXXXXXXYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRND XENTR615_PE6 NOISO QFRKFLLLQDKLPLAHVVHRTHYQGMRCLFRVCFFPKDPVEILHTDPAAFEYLYIQSRND MATCH CONSENSUS Q??????LQ???PL??VV?RT???GM?CLFR??FFPKDP??LL?RDPAAFEYLYIQSRND

AILMEGL192926_1_1_PE8 NOISO VIRERFGMDPKPEMLLGLSALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK BOVINUN_004_136_PE2 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK CALJAX_98_PE17 NOISO ------------------------------------------------------------ CANFAX_86_PE1 NOISO VIRERFGMEPKPEMLLDLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK CAVPO46_15_PE1 NOISO VIRERFGMEPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK DANRE14_13_PE1 NOISO VIKERFGMDWKFDVTLRLAALHIYITVSIARPNQKISLKHVEKEWGLEPFLPLALLPTIK DASNOGS_4069_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEWGLEPFLPPSLLQGIK ERIEUGS_4936_PE1 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK FUGRU89_1_PE126 NOISO VIKERFSMDWKSDIMLRLAALHIYITVSSARPNQKISLKHVEKEWGLEPFLPLTLLPTVK GASACGROUPIV_13_PE18 NOISO VIKERFAMDWKSDITLRLAALHIYITVSSARPNQKISLKHVEKEWGLEPFLPPTLLPTVK GORGOX_108_PE1 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK HORSEX_87_PE3 ENSECAG00000024553 VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK HSX_PE1916 ENSG00000147234 VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIK HSX_PE1917 ISOFORMIN VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIK LOXAF32_25_PE12 ISOFORMIN VIRERFGMEPKPEMLLCLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK LOXAF32_25_PE13 ENSLAFG00000017551 VIRERFGMEPKPEMLLCLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK MACEUGS_5651_PE1 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSAARPSQKFSLKNVEKEWGLEPFLPPSLLQSIK MACMUX_108_PE18 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSTTRPSQKISLKNVEKEWGLEPFLPPSLLQGIK MICMUGS_2482_PE1 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK MOUSEX_PE1762 ENSMUSG00000042425 VIRERFGMEPKPEMLLGLAALHIYITVSATRPSQKITLKNVEKEWGLEPFLPPSLLQGIK OCHPRGS_2823_PE1 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK ORYLA10_15_PE17 NOISO VIKERFGMDWKSDVTLRLAALHIYITVSSARPNQKISLKHVEKEWGLEPFLPLTLLPTVK PANTRX_107_PE19 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO VIRERFGTDPKPEMLLGLAALHIYITVSATRPSQKVSLKNVEKEWGLEPFLPPSLLQLIK PROCAGS_4183_PE1 NOISO VIRERFGTDPRPEMLLGLAALHIHITVSATRPSQKVSLKNVEKEWGLEPFLPPSLLQGIK PTEVAGS_2099_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX RABITX_58_PE1 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQGIK SORARGS_4009_PE1 NOISO VIRERFGMDPKPEMLLGLAALHIYITVSATRPSQRISLKNVEKEWGLEPFLPPSLLQGIK SPETRGS_3185_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEWGLEPFLPPSLLQGIK TURTRGS_1847_PE1 NOISO VIRERFGMDSKPEMLLGLAALHIYITVSATRPSQKISLKNVXXXXXXXXXXXXXXXXXXX XENTR615_PE6 NOISO VIRDRLGTELKPELLLVLTALHIYISVSSSRPGQKISLRAVEKEWGLDPFLPPALLQGYK MATCH CONSENSUS VI?ERF????K????L?L?ALHIYITVS??RP?QK?SLK?VEKEWGLEPFLP??LL???K

AILMEGL192926_1_1_PE8 NOISO EKNLRKSLSQQLKAHQTHSPSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA BOVINUN_004_136_PE2 NOISO EKTLRKSLSQQLKAHQTHPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA CALJAX_98_PE17 NOISO ------------------------------------------------------------ CANFAX_86_PE1 NOISO EKNLRKSLSQQLKAHQMHPSSSTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA CAVPO46_15_PE1 NOISO EKNLRKSLSQQLKAHQTQPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA DANRE14_13_PE1 NOISO EKNVCKTLSQLLKTYQHPPPAGNKVSPLQGKLQYMRVLNDLPPFGGFLFHTVGLDEKQSA DASNOGS_4069_PE1 NOISO EKNLRKSLSQQLKAHQTHPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDDKQSA ERIEUGS_4936_PE1 NOISO EKTLRKSLSQQLKAHQTHPSCGTKGSAVQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA FUGRU89_1_PE126 NOISO EKNVCKTLSQLLKTYQHPPPSGNKVPPLQGKLQYMRVLNDLPPFGGILFQTVGLDEKQSA GASACGROUPIV_13_PE18 NOISO EKNVCKSLSQLLKTYQHPPPSGNKVPPLQGKLQYMRVLNDLPPFGGILFHTVGLDEKQSA GORGOX_108_PE1 NOISO EKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA HORSEX_87_PE3 ENSECAG00000024553 EKNLRKSLSQQLKAHQTHPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA HSX_PE1916 ENSG00000147234 EKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA HSX_PE1917 ISOFORMIN EKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA LOXAF32_25_PE12 ISOFORMIN EKNLRKSLSQQLKAHQTHPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLGEKQSA LOXAF32_25_PE13 ENSLAFG00000017551 EKNLRKSLSQQLKAHQTHPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLGEKQSA MACEUGS_5651_PE1 NOISO EKNLRKSLSQQLKAHQAHPPSGAKGSQMQAKLQYLRILNELPTFTGVLFNTVGLDEKHSA MACMUX_108_PE18 NOISO EKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA MICMUGS_2482_PE1 NOISO EKNLRKSLSQQLKAHQTHPSCGTKGSATQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA MOUSEX_PE1762 ENSMUSG00000042425 EKNLRKSLSQQLKAHQMHPSSSTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKHSA OCHPRGS_2823_PE1 NOISO EKNLRKSLSQQLKAHQTYPSSGSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ORYLA10_15_PE17 NOISO EKNVCKTLSQLLKTYQHPPPSGNKVPPLQGKLQYMRVLNDLPPFGGILFHTVGLDEKQPA PANTRX_107_PE19 NOISO EKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO EKSLRKSLSQQLKAHQHQP-GGTKVSTAQAKLQYLRILNELPTFAGVLFNTVGLDEKQAA PROCAGS_4183_PE1 NOISO EKNLRKSLSQQLKAHQTHPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA PTEVAGS_2099_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXGSAIQAKLQYLRILNELPTFTGVLFNTVGLXXXXXX RABITX_58_PE1 NOISO EKNLRKSLSQQLKAHQTHPSSGSKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA SORARGS_4009_PE1 NOISO EKSFRKSLSQQLKAHQTHPSSGTKGSSTQAKLQYLRILNELPPFTGVLFNTVGLXXXXXX SPETRGS_3185_PE1 NOISO EKNLRKSLSQQLKAHQMHPSSGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLXXXXXX TURTRGS_1847_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSA XENTR615_PE6 NOISO EKSLRKALAQNLKIHQNQL-SGSKASVLQAKLRYLRILNEVPTFAGVLFNTVAMDEKTQA MATCH CONSENSUS EK???K?LSQ?LK??Q??P??G?K?S??Q?KLQY?R?LN?LP?F?G?LF?TVGL??K??A

AILMEGL192926_1_1_PE8 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL BOVINUN_004_136_PE2 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL CALJAX_98_PE17 NOISO -------------------------------------------------------QPLVL CANFAX_86_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL CAVPO46_15_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSE-------QLFRENQGVARVETSIMDA--KPLVL DANRE14_13_PE1 NOISO TTLLVGPRHGISHVIDLKNNLTTVLAEFSRVAKVQLFREHHGVARVEVVILDA--KPLVL DASNOGS_4069_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL ERIEUGS_4936_PE1 NOISO TTLLVGPRHGISHVIDLRTNLTTVLSEFS-ISKIQLFRENQGVARVETSIMDA--KPLVL FUGRU89_1_PE126 NOISO TTLLVGPRHGISHVIDLKNNLTTVLAEFSRVAKIQLYRESQGVARVELTIHEA--KPLVL GASACGROUPIV_13_PE18 NOISO TTLLVGPRHGISHVIDLKNNLTTVLAEFSRVVKIQLYRESQGVARVEVTIHEA--KPLVL GORGOX_108_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL HORSEX_87_PE3 ENSECAG00000024553 TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL HSX_PE1916 ENSG00000147234 TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL HSX_PE1917 ISOFORMIN TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL LOXAF32_25_PE12 ISOFORMIN TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL LOXAF32_25_PE13 ENSLAFG00000017551 TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL MACEUGS_5651_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFQENQSVARVETSILDA--KPLVL MACMUX_108_PE18 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL MICMUGS_2482_PE1 NOISO TTLLVGPRHGISHVIDLKCNL---ITEFSKISKRQLFHEILGLGRIQKNGGDN--QPLVL MOUSEX_PE1762 ENSMUSG00000042425 TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL OCHPRGS_2823_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XPLVL ORYLA10_15_PE17 NOISO TTLLVGPRHGISHVIDLKNNLTTVLAEFCRVSKIQLYRESQGVARVEVTIHEA--KPLVL PANTRX_107_PE19 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL PIGX_88_PE2 NOISO ------------------------------------------------------------ POEGU4A_20_PE13 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKVSKIQLFRENQGVARVETSILDA--KPLVL PROCAGS_4183_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KLPVL PTEVAGS_2099_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XPLVL RABITX_58_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL SORARGS_4009_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XPLVL SPETRGS_3185_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XPLVL TURTRGS_1847_PE1 NOISO TTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDA--KPLVL XENTR615_PE6 NOISO TTLLVGPRHGISHVIDLRTNLTTVLFEFTQVSKVQLFRESQGVARVEISVTDTKRKALVL MATCH CONSENSUS TTLLVGPRHGISHVIDL??NL?????E???????QL??E?????R???????????PLVL

AILMEGL192926_1_1_PE8 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLLPPMIKADYMH--SAHRPVPG-G BOVINUN_004_136_PE2 NOISO LMEWPEATNFACLIAGYCRLLLDSKKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G CALJAX_98_PE17 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G CANFAX_86_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G CAVPO46_15_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPVSQPLPPPMIKADYMH--SAHRPVIG-G DANRE14_13_PE1 NOISO LMEWPDASNFACLISGYYKLFVDPKRTIYCRIPGQP---YVIKAVFRHFCHLDCRSSHA- DASNOGS_4069_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPITG-G ERIEUGS_4936_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SSHHPVAG-G FUGRU89_1_PE126 NOISO LMEWPDASNFACLISGYYKLFVDPKRNIYFRAPGQS---QLTKADYRSSYHVHPRSGAA- GASACGROUPIV_13_PE18 NOISO LMEWPEASNFACLISGYYKLFVDPKRTIYFRTPGQS---QLTKAGI-SSHHAHPRSAAT- GORGOX_108_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G HORSEX_87_PE3 ENSECAG00000024553 LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G HSX_PE1916 ENSG00000147234 LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G HSX_PE1917 ISOFORMIN LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G LOXAF32_25_PE12 ISOFORMIN LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPLPMIKADYMH--SAHRPVTG-G LOXAF32_25_PE13 ENSLAFG00000017551 LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPLPMIKADYMH--SAHRPVTG-G MACEUGS_5651_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMMFSKTPSQPPPPPMNKADYMQ--NAHHPVSG-G MACMUX_108_PE18 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G MICMUGS_2482_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMIFSRPASQPLPPPMIKADYMH--SAHRPVTG-G MOUSEX_PE1762 ENSMUSG00000042425 LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADHMH--SAHRPVTG-G OCHPRGS_2823_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SANRPVTG-G ORYLA10_15_PE17 NOISO LMEWPDASNFACLISGYYKLFVDPKRTIYFRNPGQS---QLTKADYRSSHHPHPRSVAS- PANTRX_107_PE19 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G PIGX_88_PE2 NOISO -----------------------------ASPTTKPLPPPLPPLDYMH--SAHRPVTG-G POEGU4A_20_PE13 NOISO LMEWPEATNFACLIAGYCRLLVDSKKMILSRAPSQPPPPQIIKADYINAHNFQRPATA-G PROCAGS_4183_PE1 NOISO SVEWPEATN-ACLIAGYCHLLQDSEEMVFSRPISQPLPTPMIKADYMH--SAYRPVTG-S PTEVAGS_2099_PE1 NOISO LMEWLEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G RABITX_58_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMIFSRPASQPLPPPMIKADYMH--SANRPVTG-G SORARGS_4009_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPSSQPLPPPMIKADYMH--SAHRPVTG-G SPETRGS_3185_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKAXXXX--XXXXXXXX-X TURTRGS_1847_PE1 NOISO LMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMH--SAHRPVTG-G XENTR615_PE6 NOISO LMEWPEATTFSCLVAGYYRLLVDSKKGIFYRAAG-HLPPQIIKAAYSDRLSLPTVSRMPS MATCH : CONSENSUS LMEWPEATNFACLIAGYCRLL?DS?KM?FSR??SQPLP?P?IKADY????????P?????

AILMEGL192926_1_1_PE8 NOISO HLGKKES---SYVGSMG-TSPRKSSRCTPQ-PADSELVSFCYLHMREQRK------EQES BOVINUN_004_136_PE2 NOISO HLGKKES---SYVGSVG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EQES CALJAX_98_PE17 NOISO HLGKKES---SYVGSVG-TSPRKSSRCTPP-PADSELVSFCYLHMREQREG-----EQES CANFAX_86_PE1 NOISO HLGKKES---SYVGSMG-ASPRKSNHCTPP-PADSELVSFCYLHMREQRK------EQES CAVPO46_15_PE1 NOISO HLGKKES---SYVGSVG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EQES DANRE14_13_PE1 NOISO QTRSGATVLSGSAREERETSSRETT-QKTSASPIPQHLGLCHIHLKEQQQLQEFQIQAEQ DASNOGS_4069_PE1 NOISO HLGKKES---SYVGSMG-TSPRKSSNCTPP-PANSELVSFCYLHMREQRK------EQES ERIEUGS_4936_PE1 NOISO HLGKKES---CYVGSVG-TSPRKSSSCTPP-PADSELVSFCYLHMREQRK------EQES FUGRU89_1_PE126 NOISO GLPSG-----GRRGDERESSHRELVSARAVVPPEPQHLGLCHVHLREK-QFQDLPTHAEA GASACGROUPIV_13_PE18 NOISO SLPSG-----GRRGDERESSHRESGSSRALVPAESQHLGLCHVHLREQQQFQELQTHGEA GORGOX_108_PE1 NOISO HLGKKES---SYVGSVG-TSPRKSSHCTPP-PADSELVSFCYLHMREQRK------EQES HORSEX_87_PE3 ENSECAG00000024553 HLGKKES---SYVGSVG-TSPRKSSRCTPP-PANSELVSFCYLHMREQRK------EQES HSX_PE1916 ENSG00000147234 HLGKKES---SYVGSVG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EQES HSX_PE1917 ISOFORMIN HLGKKES---SYVGSVG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EQES LOXAF32_25_PE12 ISOFORMIN HLGKKES---SYLGSVA-TSPRRSSHCTPP-PADSELVSFCYLHMREQRK------EQES LOXAF32_25_PE13 ENSLAFG00000017551 HLGKKES---SYLGSVA-TSPRRSSHCTPP-PADSELVSFCYLHMREQRK------EQES MACEUGS_5651_PE1 NOISO HLGKKES---SFVGSMV-SSPGKP--CRRPPTANSELVSFCYLHMREQRK------ERES MACMUX_108_PE18 NOISO HLGKKES---SYVGSVG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EQES MICMUGS_2482_PE1 NOISO HLGKKES---SYVGSMG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EQES MOUSEX_PE1762 ENSMUSG00000042425 HLGKKES---SYVGSVG-TSPRKSSRCTTP-PADSELVSFCYLHMREQRK------EQES OCHPRGS_2823_PE1 NOISO HLGKKES---SYVGSVG-TSPRKSSRCTPS-SADSELVSFCYLHMREQRK------EQES ORYLA10_15_PE17 NOISO GLQSG-----GRRGDEREISHRESGCSRPTVPAESQHLGLCHVHLREQHQFQKIQTQAET PANTRX_107_PE19 NOISO HLGKKES---SYVGSMG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EQES PIGX_88_PE2 NOISO HLGKKES---SYVGSVG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------EPES POEGU4A_20_PE13 NOISO HVGKKEN---GLVGGSA-TVTGAAG-ASATRASDSELIRFCYLHMREQRK------ERES PROCAGS_4183_PE1 NOISO HLGKKES---NYVGSMG-TSPRKSSHCTPPLPADSELVSFCYLHMREQRK------EQES PTEVAGS_2099_PE1 NOISO HLGKKES---SYVGGMG-TSPRKSSHCTPP-PANSELVSFCYLHMREQRK------EQES RABITX_58_PE1 NOISO HLGKKES---SYVGSVG-TSPRKSSRCTPS-PADSELVSFCYLHMREQRK------EPES SORARGS_4009_PE1 NOISO HLGKKES---SYVGSMG-TSPRKPSRSTSP-PADSELVSFCYLHMREQRK------EQES SPETRGS_3185_PE1 NOISO XXXXXXX---XXXXXXX-XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXK-----EQES TURTRGS_1847_PE1 NOISO HLGKKES---SYVGSMG-TSPRKSSRCTPP-PADSELVSFCYLHMREQRK------DQES XENTR615_PE6 NOISO SIKAPPS---SSTSSER-PHSKGPTSTSSVPLEDSEPVSLCYLNLRVKE----------- MATCH CONSENSUS HLGKKES??????G?????S?R?????????PA?SELVSFCYLHMREQR???????E?ES

AILMEGL192926_1_1_PE8 NOISO RTDVNENLIFFEE-TRPRTKSDPTSRSSGQGYNVIPDDFDAASLDHEPCASRARSYTLDN BOVINUN_004_136_PE2 NOISO RMDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEAIPDDFDAASLDHEPCASRARSYTLDN CALJAX_98_PE17 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN CANFAX_86_PE1 NOISO RDGCHENLIFFEE-TRPRTKSDPTSN-SGQGYEAIPDDFDAASLNHEPCTSRARSYTLDN CAVPO46_15_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYHVVPDDFDATSLDHEPCASRARSYTLDN DANRE14_13_PE1 NOISO ELDVNENLISQVQ-SRSRTKSDPTLKSTESVA-EHD------GPTEESSSFRNRAKTLEP DASNOGS_4069_PE1 NOISO RTDVNENLIIFEE-TRPRTKSDPTSKSSGQGYDVVPDDFDAASLDHGPCASRARSYTLDN ERIEUGS_4936_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYDVVPDDFDAASLDHEPCASRARSFTLDN FUGRU89_1_PE126 NOISO ELDINENFISQQSPRRLRTKSDTTQQNTTEIPVVVE------SSANENEVYRIRAQTVSQ GASACGROUPIV_13_PE18 NOISO ELDINENCISHEPPGRPRTKSDPIQQSTEEIAGVLE------IPPVENAGFRIRAQTLCQ GORGOX_108_PE1 NOISO QTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN HORSEX_87_PE3 ENSECAG00000024553 RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYTVVPDDFDAASLDHEPCASRARSYTLDN HSX_PE1916 ENSG00000147234 RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN HSX_PE1917 ISOFORMIN RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN LOXAF32_25_PE12 ISOFORMIN RMDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVIPDDFDVASLDHEPCASRARSYTLDN LOXAF32_25_PE13 ENSLAFG00000017551 RMDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVIPDDFDVASLDHEPCASRARSYTLDN MACEUGS_5651_PE1 NOISO QTDTNENLIFFEE-TRPRTKSDPTSKSSGQGYSEAANDYDTTRPVQVPCTSRARAYTIDN MACMUX_108_PE18 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN MICMUGS_2482_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYDVIPDDFDAASLDHEPCASRARSYTLDN MOUSEX_PE1762 ENSMUSG00000042425 RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVIPDDFDAASLDHEPCASRARSYTLDN OCHPRGS_2823_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN ORYLA10_15_PE17 NOISO ELDINENFISPEPPGRPRTKSDPTQESTEETAVVIE------CPVVENKEFRARAQTMNQ PANTRX_107_PE19 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN PIGX_88_PE2 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYDVIPDDFDAASLDHEPCASRARSYTLDN POEGU4A_20_PE13 NOISO GTDINENLIFFEE-TRPRTKSDPTSKSSGQGYNGVAKECDPDGLEQDRHASRARAHTIDT PROCAGS_4183_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYDVVPDDFEAASLDHEPCASRARSYTLDN PTEVAGS_2099_PE1 NOISO RPDVNENLIFFEE-TRPRTKSDPTSKSSGQGYNMVPDDFDAASLDHEPCASRSRSYTLDN RABITX_58_PE1 NOISO RADVNENLMFFEE-TRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDN SORARGS_4009_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYDVVPDDFDATSLDHEPCASRARSYTLDN SPETRGS_3185_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGYDVVPDDFDAASLDHEPCASRARSYTLDN TURTRGS_1847_PE1 NOISO RTDVNENLIFFEE-TRPRTKSDPTSKSSGQGY-VIPDDFDAASLDHEPCASRARSYTLDN XENTR615_PE6 NOISO GRDVNQNLV-TEE-GRPRTKSDPTPKVSSSQPVME-------EHREPSEVSRSRSFTMDT MATCH . ::* : * *****. . : . * *: *: CONSENSUS ??DVNENLIFFEE?TRPRTKSDPTSKSSGQGY?????D?D??SL??EPC?SRARS?TLDN

AILMEGL192926_1_1_PE8 NOISO SLGAEALNFYCDSCKAKLQEQLG-------PRKGGR-------PGSSRDNMVDLMSLPPP BOVINUN_004_136_PE2 NOISO SLGAEALNFYCDSCKAKLQEQLG-------PRKGGR-------SGSSRDNMVDLMSLPPP CALJAX_98_PE17 NOISO SLGAEALNFYCDSCKAKLQEQLG-------PRKGGK-------PGSSRDNIVDLMSLPPP CANFAX_86_PE1 NOISO SLGAEALNFYCDSCKAKLQEQLG-------PRKGGK-------PSSSRDNMVDLMSLPPP CAVPO46_15_PE1 NOISO SLGAEALNFYCDSCKTKLQEQLG-------PRKGGR-------PGSSRDNIVDLMSLPPP DANRE14_13_PE1 NOISO S-----QKFFCEFCKAKLQAEGIIQKTGETGRLILQQCTNACSS--REGGAVDLIALPLP DASNOGS_4069_PE1 NOISO SLGAEALNFYCDSCKAKLQEQLG-------PRKGGR-------PGSSHDNMIDLMSLPPP ERIEUGS_4936_PE1 NOISO SLGAEALNFYCDSCKAKLQEQVG-------PRKGGR-------PASSRDNMVDLMSLPPP FUGRU89_1_PE126 NOISO S--QKNTRFYCDSCKARHKTDNLSGA------VNGKRCSGSCAS--REGGAVDLTALPPP GASACGROUPIV_13_PE18 NOISO S--QKASQYFCDSCKARHRAEGQSTALNSSG-SSGKHCSSACAS--RDGGAVDLMALPPP GORGOX_108_PE1 NOISO SLGAEALNFYCDSCKTKLQEQLG-------PRKGGK-------PGSSRDNIVDLMSLPPP HORSEX_87_PE3 ENSECAG00000024553 SLGAEALNFYCDSCKAKLQEQLG-------PRKAGR-------PGSSRDNMVDLMSLPPP HSX_PE1916 ENSG00000147234 SLGAEALNFYCDSCKAKLQEQLG-------PRKGGK-------PGSSRDNIVDLMSLPPP HSX_PE1917 ISOFORMIN SLGAEALNFYCDSCKAKLQEQLG-------PRKGGK-------PGSSRDNIVDLMSLPPP LOXAF32_25_PE12 ISOFORMIN SLGAESLNFYCDSCKAKLQEQLG-------PRKGGR-------PGSCRDNMVDLMSLPPP LOXAF32_25_PE13 ENSLAFG00000017551 SLGAESLNFYCDSCKAKLQEQLG-------PRKGGR-------PGSCRDNMVDLMSLPPP MACEUGS_5651_PE1 NOISO TLGAEALNFYCDSCKAKLKNQLG-------SRKSRR-------PGTSCDNMVDLMSLPPP MACMUX_108_PE18 NOISO SLGADALNFYCDSCKAKLQEQLG-------PRKGGK-------PGSSRDNIVDLMSLPPP MICMUGS_2482_PE1 NOISO TLGAEALNFYCDSCKAKFQEQQG-------PRKGGR-------PGSSRDNIVDLMSLPPP MOUSEX_PE1762 ENSMUSG00000042425 SLGAEALNFYCDSCKVKLQEQMG-------PRKGGR-------PGSSRDNMVDLMSLPPP OCHPRGS_2823_PE1 NOISO SLGPEALNFYCDSCKAKLQEQLG-------PRQGGR-------PGSSHDNMVDLMSLPPP ORYLA10_15_PE17 NOISO S--QKATRYFCDSCKAKLRAEGLSNAVK-SG-SSGKHCSIACAS--RDAGAVDLTALPPP PANTRX_107_PE19 NOISO SLGAEALTFYCDSCKAKLQEQLG-------PRKGGK-------PGSSRDNIVDLMSLPPP PIGX_88_PE2 NOISO SLGAEALNFSCDSCKAKLQEQLG-------PRKGGR-------PGSSRDNMVDLMSLPPP POEGU4A_20_PE13 NOISO HLHSDSSHFYCESCQAKIRSRLA-------SGTGGK-------PGSTRDNMVDLTSLPPP PROCAGS_4183_PE1 NOISO SLGAESLNFYCDSCKAKLQEQLG-------PRKGGR-------PGSSRDNMVDLMSLPPP PTEVAGS_2099_PE1 NOISO SLGAEALNFYCDSCKAKLQEQLV-------PRKGGR-------PGSSRDNIVDLMSLPPP RABITX_58_PE1 NOISO SLGAEALNFYCDSCKAKLQEQLG-------PRKGGR-------PGSSRDNMVDLMSLPPP SORARGS_4009_PE1 NOISO SLGAEALNFYCDSCKAKYQEPPG-------PSKGRA-------SGSSRDNMVDLXXXXXX SPETRGS_3185_PE1 NOISO SLGAEALNFYCDSCKAKFQEQQG-------PRKGGR-------PGSSRDNMVDLMSLPPP TURTRGS_1847_PE1 NOISO SLGAEALNFYCDSCKAKLQEQLG-------PRKGGR-------SGSSRDNMVDLMSLPPP XENTR615_PE6 NOISO QVKGESSQFYCDSCKAKMKSRLG-------GGGGGVKCANTCGSSNCRDNTVDLMSLPPP MATCH : *: *:.: : . . :** CONSENSUS SLG?E?L?FYCDSCKAK?Q???G????????R?GG??????????S??DN?VDLMSLPPP

AILMEGL192926_1_1_PE8 NOISO GSEEEE---EEEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ BOVINUN_004_136_PE2 NOISO GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------AQSQEQ CALJAX_98_PE17 NOISO GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ CANFAX_86_PE1 NOISO GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ CAVPO46_15_PE1 NOISO GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDSKRRA------AQSQEQ DANRE14_13_PE1 NOISO GNEEDEEI----EDGGGKLQPPTHAAIAAPPPGFRDNSSDEDDPKKGRKGIKA------S DASNOGS_4069_PE1 NOISO GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ ERIEUGS_4936_PE1 NOISO GREEEE----EEEDQSTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ FUGRU89_1_PE126 NOISO GNEEDE-V----EIGVEKLQPP-PPAIAAPPPGFRDNSSDEDDSKRGRKARTNTSQAVAS GASACGROUPIV_13_PE18 NOISO GNEEEDEA----DGGVEKPPPPPPAAIAAPPPGFRDNSSDEDDPKRGRKSRTSASLGVAS GORGOX_108_PE1 NOISO GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ HORSEX_87_PE3 ENSECAG00000024553 GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ HSX_PE1916 ENSG00000147234 GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ HSX_PE1917 ISOFORMIN GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ LOXAF32_25_PE12 ISOFORMIN GS--------------TS----LLPAIAAPPPGFRDNSSDEDDTKRRA------VQSQEQ LOXAF32_25_PE13 ENSLAFG00000017551 GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDTKRRA------VQSQEQ MACEUGS_5651_PE1 NOISO GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRV------AQSQEQ MACMUX_108_PE18 NOISO GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ MICMUGS_2482_PE1 NOISO GSEEEE-----EEEDETS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ MOUSEX_PE1762 ENSMUSG00000042425 GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ OCHPRGS_2823_PE1 NOISO GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ ORYLA10_15_PE17 NOISO GNEEEEEEEEVVDGGGAKLQP-PQPAIAAPPPGFRDNSSDEEDPKRGRKARSSASVGLPS PANTRX_107_PE19 NOISO GSEEEE----EEENETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ PIGX_88_PE2 NOISO GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ POEGU4A_20_PE13 NOISO GNND------EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRAA-----AQGQEQ PROCAGS_4183_PE1 NOISO GSEEEX---XXXXXX-XX----XXXXXXXXPPGFRDNSSDEDDSKRRA------VQSQEQ PTEVAGS_2099_PE1 NOISO GSEEEE----EEEDESTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ RABITX_58_PE1 NOISO GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ SORARGS_4009_PE1 NOISO XXXXXX---XXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXX------XX-XXX SPETRGS_3185_PE1 NOISO GSEEEE----EEEDETTS----LLPAIAAPPPGFRDNSSDEDDPKRRA------VQSQEQ TURTRGS_1847_PE1 NOISO GSEEEE----EEEDESTS----LLPSIAAPPPGFRDNSSDEEDPKRRA------VQSQEQ XENTR615_PE6 NOISO ELEKGEEEQEEKEGKTTA----LLPAAAPPPPGFGDNSSDEDEPKQKIGKVQEKIKGPEK MATCH CONSENSUS G?EEEE??????E???T?????LLPAIAAPPPGFRDNSSDEDDPKRR????????Q?QEQ

AILMEGL192926_1_1_PE8 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P BOVINUN_004_136_PE2 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P CALJAX_98_PE17 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P CANFAX_86_PE1 NOISO GRHLCGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P CAVPO46_15_PE1 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P DANRE14_13_PE1 NOISO TA--VAQGQDEVPVTLIDNVTTRTVQDHAQELDDALVSTLQALEALAASEDYPHHQQQTP DASNOGS_4069_PE1 NOISO GRHLHGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P ERIEUGS_4936_PE1 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEXXXXXX---X FUGRU89_1_PE126 NOISO GK--LVQAKEDVPVTLIDNVSTRTVRDHAQELDDALVSTLQALEALAASEDFPHHPQQS- GASACGROUPIV_13_PE18 NOISO GK--LAQTKEAVPVTLIDNVATRTVRDHAQELDDALVSTLQALEALAASEDYPHHPQQP- GORGOX_108_PE1 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P HORSEX_87_PE3 ENSECAG00000024553 GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P HSX_PE1916 ENSG00000147234 GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P HSX_PE1917 ISOFORMIN GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P LOXAF32_25_PE12 ISOFORMIN GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P LOXAF32_25_PE13 ENSLAFG00000017551 GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P MACEUGS_5651_PE1 NOISO GRPLCGILYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAAAEDCPHPP---P MACMUX_108_PE18 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P MICMUGS_2482_PE1 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P MOUSEX_PE1762 ENSMUSG00000042425 GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P OCHPRGS_2823_PE1 NOISO GRHLR-LLYDEIPVTDS--V-----QTTRDHAEDDLVSTLQLLEALAASEDGPHPQ---P ORYLA10_15_PE17 NOISO GK--SLHANEDVPVTLIDNVATRTVRDHAQELDDALVSTLQALEALAASEDYPHHPQQP- PANTRX_107_PE19 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P PIGX_88_PE2 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P POEGU4A_20_PE13 NOISO GRHLCGILYDEIPVTLIDSVQPRTVRDHAQELDDALVSTLQALEALAASEDCPHPP---P PROCAGS_4183_PE1 NOISO GR-LRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P PTEVAGS_2099_PE1 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTL-ALEALTASEDGPHPP---P RABITX_58_PE1 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P SORARGS_4009_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X SPETRGS_3185_PE1 NOISO GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---P TURTRGS_1847_PE1 NOISO GRHLHGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP---A XENTR615_PE6 NOISO SRDALQPGYEDLPVTLIDSVQTRTVRDHARELDDALVSTLQALEALAASEDFPTPA---P MATCH CONSENSUS GR?L???LYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASED?PHPP???P

AILMEGL192926_1_1_PE8 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKESLLA BOVINUN_004_136_PE2 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA CALJAX_98_PE17 NOISO PQAAGLGAAAHISPGCAVFSATQEAE--ARESLEPGSEPRFHHPTPAWVTEIINKNVLAV CANFAX_86_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKESLLA CAVPO46_15_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNK----- DANRE14_13_PE1 NOISO QTTAGLIVLAAITPESSLDSGHETNSSELTDVSEMVSAMKQHQNQAYLLAHHINKERLFS DASNOGS_4069_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA ERIEUGS_4936_PE1 NOISO XXXXXLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA FUGRU89_1_PE126 NOISO TQTAGLIVLAAITPESSLDSGHETNSSELTDVSEMVSAMKQNQNQASFWAHHINKERILC GASACGROUPIV_13_PE18 NOISO TQTAGLIVLAAITPESSLDSGHETNSSELADVSEMVSAMKQNQNQAYLLAHHINKERILC GORGOX_108_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA HORSEX_87_PE3 ENSECAG00000024553 PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA HSX_PE1916 ENSG00000147234 PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA HSX_PE1917 ISOFORMIN PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA LOXAF32_25_PE12 ISOFORMIN PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA LOXAF32_25_PE13 ENSLAFG00000017551 PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA MACEUGS_5651_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMVSAMKQRQNATYFLAQHINKEGLMA MACMUX_108_PE18 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA MICMUGS_2482_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA MOUSEX_PE1762 ENSMUSG00000042425 PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA OCHPRGS_2823_PE1 NOISO HQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKESLLA ORYLA10_15_PE17 NOISO TQTAGLIVLAAITPESSLDSGHETNSSELTDVSEMVSAMKQNQNQAYLLAHHINKERILC PANTRX_107_PE19 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA PIGX_88_PE2 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA POEGU4A_20_PE13 NOISO QQTAGLIVLAAITPESSLDSGHETNSSELTDVSEMVSAMKQHQNAAYFLTQHINKENLLA PROCAGS_4183_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEVMSAMKQHQNTTYFLAQHLNKDSLLA PTEVAGS_2099_PE1 NOISO PQTA-LIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLKKDSLLA RABITX_58_PE1 NOISO PQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKESLLS SORARGS_4009_PE1 NOISO XXXXXLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLA SPETRGS_3185_PE1 NOISO PQTAPLGGARNLQKQSTRARGWAQGFE---------------------------SRXXXX TURTRGS_1847_PE1 NOISO PQTAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XENTR615_PE6 NOISO QPTTGLIVLAAITPESSLDSGHETNSSELTDVSEMVTAMKQHHNTTYILAHHLNKESLLS MATCH CONSENSUS ?QTAGLIVLA?ITPESSLDSGHETNSSELTD?SEM?SAMKQHQN??Y?LA?H?NK??LL?

AILMEGL192926_1_1_PE8 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---ALQPA---VTGQSPGPPGARRKLPP-- BOVINUN_004_136_PE2 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNS---SLQPV---VAGQSPGPPGARRKLPS-- CALJAX_98_PE17 NOISO ESKNTFPSLSPPLHSAHLQPCILTRPDCQP---SLTDM---SE-MMSXXPGARRKLPQ-- CANFAX_86_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYALGRPDPNP---ALQPT---VTGQSPGPPGTRRKLPT-- CAVPO46_15_PE1 NOISO --DLPFRIQSCAAQAVLTAPYSLGRPDPNT---SLQPA---VTGQSPGPPGARRKLPQ-- DANRE14_13_PE1 NOISO RRDFPLTIPGCTTQAIGGGAFSMSQIRGSCPPKPVILSKTLPLKISPNKEISHSDKSAEW DASNOGS_4069_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPA---VTGQSPGPPGARRKLPQ-- ERIEUGS_4936_PE1 NOISO CKDLPFRIQSCAAQAVLTAPYSLGRPDPNA---SLPPA---VTGQSPGPPGARRKLPQ-- FUGRU89_1_PE126 NOISO RRDFPLAIPGCTTKTIGTGAFSVGQIRAGCPPKQVILSKTVPFKVSPTQDSAELSVVTEQ GASACGROUPIV_13_PE18 NOISO RRDFPLAIPGCTAKTIGTGAFSVGQIRAGCPTKQVILSKTIPFKVSPCQDPAVLNVVTEQ GORGOX_108_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNT---SLQPI---ATGQSPGPPGARRKLPQ-- HORSEX_87_PE3 ENSECAG00000024553 RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPA---VTGQSPGPPGARRKLPQ-- HSX_PE1916 ENSG00000147234 RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPI---ATGQSPGPPGARRKLPQ-- HSX_PE1917 ISOFORMIN RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPI---ATGQSPGPPGARRKLPQ-- LOXAF32_25_PE12 ISOFORMIN RKDLPFRIQTCAAQAVLTAPYSLGRPDPNP---SRQPA---VTGQSPGPPGARRKLPQ-- LOXAF32_25_PE13 ENSLAFG00000017551 RKDLPFRIQTCAAQAVLTAPYSLGRPDPNP---SRQPA---VTGQSPGPPGARRKLPQ-- MACEUGS_5651_PE1 NOISO RKDLSFRIPSCTTQAVLTAPYPLGRQEASLASAALERQ---PPGQGSGPTGGRRRLDP-- MACMUX_108_PE18 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPI---ATGQSTGPTGARRKLPQ-- MICMUGS_2482_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNA---SLQPV---ITSQSPGPPGARRKLPQ-- MOUSEX_PE1762 ENSMUSG00000042425 RKDLPFRIQSCAAQAVLTAPYALGPPDPNP---SPQPA---VTGQSPAPTGARRKIPQ-- OCHPRGS_2823_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYSLGHPDPNP---SLQPA---VTGQSPGPPGARRKLPP-- ORYLA10_15_PE17 NOISO RRDFPLAIPGCTAKTIGTGAFSVGQIRAGCPPKQVILSKTVPFKVSPSQDSAILSVLADQ PANTRX_107_PE19 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPI---ATGQSPGPPGARRKLPQ-- PIGX_88_PE2 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPA---VTGQSPGPPGARRKLPP-- POEGU4A_20_PE13 NOISO RKDLPFRIQSCAAQAVLTSPYPLSRQDPSP---SLKPA---FSTQNPSLPNCKSKQEQ-- PROCAGS_4183_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYALGRPDPNP---SLQPA---VAGQSPGPPGARRKLPQ-- PTEVAGS_2099_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRSDPNP---SLQPA---IPGQSPGPPGTRRKLPQ-- RABITX_58_PE1 NOISO RKDLPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPA---VTGQSPGPPGARRKLPQ-- SORARGS_4009_PE1 NOISO RKDLPFRIQSCATQAVLTAPYSLGRPDSNS---SLQPA---VTGQSPGPPGARRKVPP-- SPETRGS_3185_PE1 NOISO XX-----X---------------------------------------------------- TURTRGS_1847_PE1 NOISO XXXXPFRIQSCAAQAVLTAPYSLGRPDPNP---SLQPA---VTGQSPGAPGARRKVPP-- XENTR615_PE6 NOISO RKDLPFRIQTCAAQAVLASPYTLGCQETSPLVKSTILQQSIATTVSKQEPTARSPSPL-- MATCH CONSENSUS R?D?PFRI??C?AQAVLT?PY?LG?????????????????????SP????AR???????

AILMEGL192926_1_1_PE8 NOISO SESQPPQRERTYALAVHPALSPQL---SEQKNL-SLLSPVPEDKGPGHMRAGLEMSLRAA BOVINUN_004_136_PE2 NOISO SEAQ-PQRERTYALAVHPALSPQL---SEPKNL-SLLSPVPEDKGPGHTRAGLEMSLRAA CALJAX_98_PE17 NOISO SEGQ-AQGERTYSLAVHPALSPQL---SEQKNL-SLLSPVPEDKGPGHTRAGLEMSLRTA CANFAX_86_PE1 NOISO SESQ-PQRERTYALAVHPALSPQL---SEQKNL-SLLSPVPEDKGPGHTRAGLEVSLRAA CAVPO46_15_PE1 NOISO SESQ-AQGERTYSLAVHPALSPQLSQLSEQKNL-SLLPPVPEDKGPGHTRAGMEMSLRAA DANRE14_13_PE1 NOISO GKSHEANGEKDIEITEKGLVTECLEE--------SKLQISEELKAPEHG----------S DASNOGS_4069_PE1 NOISO PEAQ-PQGERTYTLAVHPALSPQL---SEQKNL-SLLSPVPEDRGPGHTRAGLEMSLRAA ERIEUGS_4936_PE1 NOISO PEAQ-AQRERTYALAVHPALSPQL---SEPKNL-SLLSPVPEDKGPGHTRPGLEMSLRAA FUGRU89_1_PE126 NOISO AGKQ------DAVCTEQAASVKIRSESTKVNTPDTVSNSHEE-KAPDAS----------L GASACGROUPIV_13_PE18 NOISO GGNQ------ETQ-KEQKAEMKANPESTKANTPDDHSKSPDELKVSSAS----------L GORGOX_108_PE1 NOISO SEGQ-VQGERTYSLAVHPALSPQL---SEQKNL-SLLSPVPEDKGPGHTRAGLEMSLRAA HORSEX_87_PE3 ENSECAG00000024553 SEAQ-SQRERTYALAVHPALSPQL---SEQKNL-SLLSPVPED<