Alignment of the gene Family HOG000113022 of HOGENOM

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Threshold: 50% 80% 100%
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Isoforms are ON
AILMEGL192891_1_1_PE28 NOISO NMERELRQLSKAKAKAQRSGQLRDEAALCHQLGELLASHGRYAEALREHQHELQLLESVD ANOCA949_PE5 NOISO ------------------------------------------------------------ BOVIN14_1_PE29 NOISO SLERELRQLSKAKTKAQRSGQLREEASVCHQLGELLASHGCYAEALREHQQELQLLETTD CALJA16_53_PE31 ENSCJAG00000021411 SLERELRQLSKAKAKVQRAGHLREEAALCHQLGELLAGHGRYAEALQQHWQELQLRESVG CALJA16_53_PE32 ISOFORMIN ------------------------------------------------------------ CANFA13_42_PE31 NOISO SAERELRQLSKAKAKAQRSGQLREEAAACHQLGELLASSGRYAEALREHQHELQLLESVD CAVPO95_4_PE29 NOISO ------------------------------------------------------------ DANRE17_10_PE1 NOISO TSTKEIKQLQKAKSKAQSSNNLKEEASLCNQLGEVYAKTGDYQAAIEEHRQELALSEILH DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO ------------------------------------------------------------ ERIEUGS_7142_PE4 NOISO ------------------------------------------------------------ FELCAGS_5236_PE3 NOISO ------------------------------------------------------------ FUGRU10_1_PE41 ENSTRUG00000007494 SSTREIKQLQKAKSKAQNCSNLKEEANICNQLGELFSKSGDYKAAISEHRQELVLSEALN GASACGROUPXV_8_PE3 ISOFORMIN ------------------------------------------------------------ GASACGROUPXV_8_PE4 ENSGACG00000009209 ------------------------------------------------------------ GORGO8_150_PE69 ENSGGOG00000016222 -----------------------------------------Q------------------ GORGO8_150_PE70 ISOFORMIN SLERELRQLSKAKAKAQRAGQRREEAALCHQLGELLAGHGRY------------------ HORSE9_85_PE50 ENSECAG00000014231 SLERELRQLYKGKTKAQRSGQLREEAALCHQLGELLASHGRYAEALREHQQELQLLESAN HORSE9_85_PE51 ISOFORMIN ------------------------------------------------------------ HS8_PE3560 ENSG00000160949 SLERELRQLSKAKAKAQRAGQRREEAALCHQLGELLAGHGRYAEALEQHWQELQLRERAD HS8_PE3561 ISOFORMIN SLERELRQLSKAKAKAQRAGQRREEAALCHQLGELLAGHGRYAEALEQHWQELQLRERAD HS8_PE3562 ISOFORMIN ------------------------------------------------------------ LOXAF185_PE10 ISOFORMIN ------------------------------------------------------------ LOXAF185_PE9 ENSLAFG00000027120 SLERELRQLSKAKAKAQRNGQLREEAASCHQLGELLASHGRYAEALEEHQRELQLLESAD MACEUGS_6643_PE1 NOISO ------------------------------------------------------------ MACMU8_150_PE8 ENSMMUG00000002655 ------------------------------------------------------------ MACMU8_150_PE9 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE18 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE19 ENSMODG00000010893 ------------------------------------------------------------ MOUSE15_PE693 NOISO ------------------------------------------------------------ OCHPRGS_3363_PE1 NOISO ------------------------------------------------------------ ORYLA22_10_PE32 NOISO ----PLAELQKAKSKAQASNNLKEEANICNQLGELLSRNGDYEAAIREHQQELSLSESLD PANTR8_151_PE18 ENSPTRG00000020702 ------------------------------------------------------------ PONPY8_158_PE43 NOISO ------------------------------------------------------------ PROCAGS_4222_PE3 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE5 NOISO ------------------------------------------------------------ RAT7_PE1316 NOISO TLEQELRQLSKAKARAQRNGQLCEEAVCCHQLGELLASHGRFQEALEEHQQELHLLESVQ TETNG10_PE412 NOISO ------------------------------------------------------------ TURTRGS_2770_PE5 NOISO ------------------------------------------------------------ XENTR8389_PE1 ISOFORMIN ------------------------------------------------------------ XENTR8389_PE2 ENSXETG00000020475 ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192891_1_1_PE28 NOISO DPLGCAVAHRKIGERLAELEDYSAALKHQHRYLELAHSLSNHTEVQRAWATIGRTYLDIY ANOCA949_PE5 NOISO ------------------------------------------------------------ BOVIN14_1_PE29 NOISO DPLGCAVAHRKIGERLAEMEDYSAALQHQHRYLELACALSNHVEQQRAWATIGRTHLDIY CALJA16_53_PE31 ENSCJAG00000021411 DRLGCAVAHRKIGERLAEMEDYPAALQHQHRYLELARSLGNHTELQRAWATIGRTHLDIY CALJA16_53_PE32 ISOFORMIN ------------------------------------------------------------ CANFA13_42_PE31 NOISO DALGCAVAHRKIGERLAELEDYSAALKHQHRYLELACSLSNHTEQQRAWATIGRTYLDIY CAVPO95_4_PE29 NOISO ------------------------------------------------------------ DANRE17_10_PE1 NOISO DVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLF DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO ------------------------------------------------------------ ERIEUGS_7142_PE4 NOISO ------------------------------------------------------------ FELCAGS_5236_PE3 NOISO ------------------------------------------------------------ FUGRU10_1_PE41 ENSTRUG00000007494 DVIGRAVANRKIGECYAEMGNFKAALKHQRCHLDLARSVRDHAEEQRALATIGRTYLFRY GASACGROUPXV_8_PE3 ISOFORMIN ------------------MGNIEAALKNQQCHLDLARSVGDYAEEQRALATIGRTYLFRY GASACGROUPXV_8_PE4 ENSGACG00000009209 ------------------------------------------------------------ GORGO8_150_PE69 ENSGGOG00000016222 ---------------------------HQHQYLELAHSLRNHTELQRAWATIGRTHLDIY GORGO8_150_PE70 ISOFORMIN ---------------------------HQHQYLELAHSLRNHTELQRAWATIGRTHLDIY HORSE9_85_PE50 ENSECAG00000014231 DPLGCAVAHRKIGERLAEMEDYSAALQHQHHYLELARSLSNHIELQRAWATIGRTHLDIY HORSE9_85_PE51 ISOFORMIN ------------------------------------------------------------ HS8_PE3560 ENSG00000160949 DPLGCAVAHRKIGERLAEMEDYPAALQHQHQYLELAHSLRNHTELQRAWATIGRTHLDIY HS8_PE3561 ISOFORMIN DPLGCAVAHRKIGERLAEMEDYPAALQHQHQYLELAHSLRNHTELQRAWATIGRTHLDIY HS8_PE3562 ISOFORMIN ------------------------------------------------------------ LOXAF185_PE10 ISOFORMIN ------------------------------------------------------------ LOXAF185_PE9 ENSLAFG00000027120 DALGCAVAHRKIGERLAEMEDYSAALKHQQRYLELAYSLSNHVELQRAWATIGRTYLDIY MACEUGS_6643_PE1 NOISO ------------------------------------------------------------ MACMU8_150_PE8 ENSMMUG00000002655 ------------------------------------------------------------ MACMU8_150_PE9 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE18 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE19 ENSMODG00000010893 ------------------------------------------------------------ MOUSE15_PE693 NOISO ------------------------------------------------------------ OCHPRGS_3363_PE1 NOISO ------------------------------------------------------------ ORYLA22_10_PE32 NOISO DVIGRAVANRKIGECYAEMGNIKAALKHQQCHLDLAHSVGDHAEVQRALATIGRTYLFRY PANTR8_151_PE18 ENSPTRG00000020702 ------------------------------------------------------------ PONPY8_158_PE43 NOISO ------------------------------------------------------------ PROCAGS_4222_PE3 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE5 NOISO ------------------------------------------------------------ RAT7_PE1316 NOISO DTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLDVY TETNG10_PE412 NOISO ------------------------------------------------------------ TURTRGS_2770_PE5 NOISO ------------------------------------------------------------ XENTR8389_PE1 ISOFORMIN ------------------------------------------------------------ XENTR8389_PE2 ENSXETG00000020475 ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192891_1_1_PE28 NOISO DHCQSQDTLLQAQTAFEKSLAIVDEKLQ---GTLAKRELSEMRTRLYLNLGLTFESLRQM ANOCA949_PE5 NOISO -----------------------------------------MRARLYLNLGLVYDGLKDP BOVIN14_1_PE29 NOISO DHHQSQDALQQAQDAFEKSLAILDEKLQ---GSLPKRELSEMRTRIYLNLGLTCESLQQV CALJA16_53_PE31 ENSCJAG00000021411 DHCQSRDALLQAQAAFEKSLAIVDEELE---GTLAQGELNEMRARLYLNLGLTFESLQQT CALJA16_53_PE32 ISOFORMIN -----------------------------------------MRARLYLNLGLTFESLQQT CANFA13_42_PE31 NOISO DHCQSKDTLLQAQAAFEKSLAIVDEKLQ---GTLAKRELNEMRTRLYLNLGLTFESLQQM CAVPO95_4_PE29 NOISO -----------------------------------------MRTRLYLNLGLTFESLQQM DANRE17_10_PE1 NOISO DSDQSANSLKHAEDAFKKSLAIVDERLE---GTVSPREISEMKARLLLNLGCVYDGMKEP DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO -----------------------------------------MRTRLYLNLGLTFERLQQM ERIEUGS_7142_PE4 NOISO ------------------------------------------------------------ FELCAGS_5236_PE3 NOISO -----------------------------------------MRTRLYLNLGLTFESLQQM FUGRU10_1_PE41 ENSTRUG00000007494 ESDQSRSSLEQAEDAFRKSLAIVDDCLEVNTATVSVREISEMKARLFLNLGLVCDHLGEP GASACGROUPXV_8_PE3 ISOFORMIN ESDQSKNSLSQAEEVFKKSLCIVDEHLE---GTVPEREIREMKARLFLNLGLVCDHLGEH GASACGROUPXV_8_PE4 ENSGACG00000009209 -----------------------------------------MKARLFLNLGLVCDHLGEH GORGO8_150_PE69 ENSGGOG00000016222 DHCQSRDALLQAQAAFEKSLAIVDEELE---GTLAQGELNEMRTRLYLNLGLTFESLQQT GORGO8_150_PE70 ISOFORMIN DHCQSRDALLQAQAAFEKSLAIVDEELE---GTLAQGELNEMRTRLYLNLGLTFESLQQT HORSE9_85_PE50 ENSECAG00000014231 DHCQSQDALLQAQTAFGKSLAIVDEKLQ---GTLPKRELSEMRTRLYLNLGLTFESLQQM HORSE9_85_PE51 ISOFORMIN ---------------------------------MPKRELSEMRTRLYLNLGLTFESLQQM HS8_PE3560 ENSG00000160949 DHCQSRDALLQAQAAFEKSLAIVDEELE---GTLAQGELNEMRTRLYLNLGLTFESLQQT HS8_PE3561 ISOFORMIN DHCQSRDALLQAQAAFEKSLAIVDEELE---GTLAQGELNEMRTRLYLNLGLTFESLQQT HS8_PE3562 ISOFORMIN -----------------------------------------MRTRLYLNLGLTFESLQQT LOXAF185_PE10 ISOFORMIN ------------------------------------------------------------ LOXAF185_PE9 ENSLAFG00000027120 DHSQSRDALLQAQAAFEKSLAIVDEKLE---GAVARRELIEMRTRLYLNLGLTFDSLQQA MACEUGS_6643_PE1 NOISO -----------------------------------------MRTRLYLNLGLTFDSLKQP MACMU8_150_PE8 ENSMMUG00000002655 -----------------------------------------MRTRLYLNLGLTFESLQQT MACMU8_150_PE9 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE18 ISOFORMIN --------------------------------VLTQQELSEMRTRLYLNLGLTFDSLKQP MONDO3_446_PE19 ENSMODG00000010893 -----------------------------------------MRTRLYLNLGLTFDSLKQP MOUSE15_PE693 NOISO --------------------------------MLTQRELSEMRTRLYLNLGLTCESLQQT OCHPRGS_3363_PE1 NOISO -----------------------------------------MRTRLYLNLGLTFESLKQT ORYLA22_10_PE32 NOISO ESDQSKSSLKKAEDAFRKSLAIVDERLG---GTVPDREIAEMKARLFLNLGIVCDHLGES PANTR8_151_PE18 ENSPTRG00000020702 -----------------------------------------MRTRLYLNLGLTFESLQQT PONPY8_158_PE43 NOISO -----------------------------------------MRTRLYLNLGLTFESLQQT PROCAGS_4222_PE3 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE5 NOISO -----------------------------------------MRTRLYLNLGLTFESLQEV RAT7_PE1316 NOISO DHCQSRDSLLQAQAAFEKSLAIVDEKLE---GMLTQRELSEMRTRLYLNLGLTCESLQQT TETNG10_PE412 NOISO -----------------------------------------MKARLFLNLGLVYDHLGEP TURTRGS_2770_PE5 NOISO -----------------------------------------MRTRLYLNVGLTCDSLQQA XENTR8389_PE1 ISOFORMIN --------------------------------KVCVRELNEMRARLYLNLGLLYDQLRRT XENTR8389_PE2 ENSXETG00000020475 -----------------------------------------MRARLYLNLGLLYDQLRRT MATCH CONSENSUS ?????????????????????????????????????????M??RL?LNLGL????L???

AILMEGL192891_1_1_PE28 NOISO APCNDYFRKSIFLAEQNHLYEDLFRARYNLGAIHWRRGQHSQAMRCLEGARECARVLRKE ANOCA949_PE5 NOISO AKHTYYIKKSIYISEQTQLLEDLYRAYYNMGNIHLREGQHSKAMRCLERARECACKMKEK BOVIN14_1_PE29 NOISO ALCSAYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRRGQHSQAMRCLEGARECARVLKQA CALJA16_53_PE31 ENSCJAG00000021411 ALCNDYFRKSIFLSEQNHLYEDLFRARYNLGTVHWRAGQHSQAMRCLEGARECARTMKKR CALJA16_53_PE32 ISOFORMIN ALCNDYFRKSIFLSEQNHLYEDLFRARYNLGTVHWRAGQHSQAMRCLEGARECARTMKKR CANFA13_42_PE31 NOISO APCNDYFRKSIFLAEQNHLHEDLFRARYNLGAIHWRKGQHSQAMRCLEGARECARVLRKE CAVPO95_4_PE29 NOISO ALCNVEARKEQSICRHNHLYEDLYRARYNLGTIHWRAGQHSQAMRCLEGARECARAMKKR DANRE17_10_PE1 NOISO QRCSDLIRQSIYIAEKNNLLEDLYRANFNLGSIHFRNGQHSRAMRCFEQSKECARKMKDK DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO ALCNDYFKKSIFLAEQNHLYEDLFRARYNLGAIHWCAGQHSQAMRCLEGARECARAMKMR ERIEUGS_7142_PE4 NOISO ------------------------------------------------------------ FELCAGS_5236_PE3 NOISO APCNDYFRKSIFLAEQNRLYEDLFRARYNLGAIHWRRGQHSQAMRCLEGARECARALRKE FUGRU10_1_PE41 ENSTRUG00000007494 KRCSEFIRRSVFIAEKSQLLEDLFRANFNLGNIFYRNGQKSNAVRCLEQAKECARKMKDK GASACGROUPXV_8_PE3 ISOFORMIN KRCSEFIRRSVFIAEKSHLLEDLYRANFNLGNIYFRHGQWSKAVRCLEQAKECARKIKDK GASACGROUPXV_8_PE4 ENSGACG00000009209 KRCSEFIRRSVFIAEKSHLLEDLYRANFNLGNIYFRHGQWSKAVRCLEQAKECARKIKDK GORGO8_150_PE69 ENSGGOG00000016222 ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKR GORGO8_150_PE70 ISOFORMIN ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKR HORSE9_85_PE50 ENSECAG00000014231 ALCNDYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRRGQHSQAMRCLEGARECARIMKKE HORSE9_85_PE51 ISOFORMIN ALCNDYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRRGQHSQAMRCLEGARECARIMKKE HS8_PE3560 ENSG00000160949 ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKR HS8_PE3561 ISOFORMIN ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKR HS8_PE3562 ISOFORMIN ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKR LOXAF185_PE10 ISOFORMIN ------------------------------------------------------------ LOXAF185_PE9 ENSLAFG00000027120 ALCSNYFKKSIFLSEQNHLHEDLFRARYNLGTIHWRRGQHSKAMRCLEGARECARALKRG MACEUGS_6643_PE1 NOISO ALCSDYIKKSIFLSEQNHLYEDLFRARYNLGTIHWRGGQHSKAMRCLEGARECARVLKRK MACMU8_150_PE8 ENSMMUG00000002655 ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTVHWRAGQHSQAMRCLEGARECAHTMRKR MACMU8_150_PE9 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE18 ISOFORMIN ALCSDYIKKSIFLSEQNHLYEDLYRARYNLGTIHWRAGEHSKAMRCLEGARECARIMKRK MONDO3_446_PE19 ENSMODG00000010893 ALCSDYIKKSIFLSEQNHLYEDLYRARYNLGTIHWRAGEHSKAMRCLEGARECARIMKRK MOUSE15_PE693 NOISO ALCNNYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRGGQHSQAMRCLEGARECARAMKMR OCHPRGS_3363_PE1 NOISO TLCHDYFKKSIFLAEQNHLYEDLFRARYNLGAIHWREGHHSQAMRCLEGARECARTMKRR ORYLA22_10_PE32 NOISO KHCSEFIRRSVFIAVKSQLLEDLYRANFNLGNIYFRNGEHSNAVRCLEQAKECARKMKDK PANTR8_151_PE18 ENSPTRG00000020702 ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGKHSQAMRCLEGARECAHTMRKR PONPY8_158_PE43 NOISO ALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTVHWRAGQHSQAMRCLEGARECAHTMRKR PROCAGS_4222_PE3 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE5 NOISO ALCNSYFKKSIFLAEQNHLHEDLFRARY-LGAIHWRRGQHSQAMRCLEGARECARALRKG RAT7_PE1316 NOISO AQCNNYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRGGQHSQAMRCLEGARECARAMKMR TETNG10_PE412 NOISO KLCSEFIRRTVFIAEKSELLEDLYRANFNLGNIYFRNGQKPNAVRCLEQAKECARKMKDK TURTRGS_2770_PE5 NOISO ALCHAYFTKSIFLAEQNHLYEDLFRARYNLGAIHWRRGQHSQAMRCLEGARKCARTLKQG XENTR8389_PE1 ISOFORMIN DKCSFYIRKSVFISEQNQLYEDLYRANFTLAGIHMRNKEHSKAIRCWEAARECARRMRDK XENTR8389_PE2 ENSXETG00000020475 DKCSFYIRKSVFISEQNQLYEDLYRANFTLAGIHMRNKEHSKAIRCWEAARECARRMRDK MATCH CONSENSUS ??C??????S?F??E???L?EDL?RA??NLG????R?G??S?A?RCLE?A?ECA??????

AILMEGL192891_1_1_PE28 NOISO LMESECCMLISQ-ILQDLGDFLAAKRALKKAYRLGIQKPLQKAAVCRALKY-VLAVVRLQ ANOCA949_PE5 NOISO HMESECCAGIAQ-VLLSLGDFVAAKRSLKKAYRMGSQQPQQRESVCHNLRY-VSKVTRLQ BOVIN14_1_PE29 NOISO FLESECCLLLSQ-VLLDLGDFLAAKRALKKAYRLGSQKPLQKASVCRTLKY-VLAVVQLQ CALJA16_53_PE31 ENSCJAG00000021411 FMESECCMAIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRATICQNLQH-VLAVVRLQ CALJA16_53_PE32 ISOFORMIN FMESECCMAIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRATICQNLQH-VLAVVRLQ CANFA13_42_PE31 NOISO LMESECCVLVSQ-ILQDLGDFLAAKRALKKAYRLGFQKPLQKAAVCRTLKY-VLAVVQLQ CAVPO95_4_PE29 NOISO FMESECCVVVSQ-ILQDLGDFLAAKRALKKAYRLGSQKPAQRAAVCQSLKYAVLAVVQLQ DANRE17_10_PE1 NOISO FSESECFHSIGK-ILLHLGDFAAARRSLKKAFCLGSQQPSDREAVKKDFRHAI-RGCQLE DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO FMESECCVTISQ-ILQDLGDFLAAKRALKKAYRLGSQKHAQRAAVCQSLKY-VLAVIQLQ ERIEUGS_7142_PE4 NOISO ------------------------------------------------------------ FELCAGS_5236_PE3 NOISO LMESDCCVLISQ-IFQDLGDFLAAKRALKKAYRLGFQKPLQKAAICRTLKY-XXXXXXXX FUGRU10_1_PE41 ENSTRUG00000007494 FGESECFHCIGK-VQLSLGDFVAARRSLKKALLLGSQQTVDRQSVKKAFKYAD-RGCKLE GASACGROUPXV_8_PE3 ISOFORMIN FSESECFHCIGK-VQLSLADFVAARRSLKKAVLLGSQQPLDRQTVKRAFKYAD-LGCKLE GASACGROUPXV_8_PE4 ENSGACG00000009209 FSESECFHCIGK-VQLSLADFVAARRSLKKAVLLGSQQPLDRQTVKRAFKYAD-LGCKLE GORGO8_150_PE69 ENSGGOG00000016222 FMESECCVAIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQH-VLAVVRLQ GORGO8_150_PE70 ISOFORMIN FMESECCVAIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQH-VLAVVRLQ HORSE9_85_PE50 ENSECAG00000014231 FMESECCLLLSQ-VLQDLGDFLAAKRALKKAYRLGSQKPLQKAVICRTLKH-VLAVVQLQ HORSE9_85_PE51 ISOFORMIN FMESECCLLLSQ-VLQDLGDFLAAKRALKKAYRLGSQKPLQKAVICRTLKH-VLAVVQLQ HS8_PE3560 ENSG00000160949 FMESECCVVIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQH-VLAVVRLQ HS8_PE3561 ISOFORMIN FMESECCVVIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQH-VLAVVRLQ HS8_PE3562 ISOFORMIN FMESECCVVIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQH-VLAVVRLQ LOXAF185_PE10 ISOFORMIN ------------------------------------------------------------ LOXAF185_PE9 ENSLAFG00000027120 FMESECCLAISQ-ILQDLGDFLAAKRALKKAYRLGSQKPLQREVVCSNLKYAVLKVIRLQ MACEUGS_6643_PE1 NOISO FMESECCVVVAQ-ILQDLGDFVAAKRALKKAYRLGSQQPRQRHTVCRSLKY-VLKVVSLQ MACMU8_150_PE8 ENSMMUG00000002655 FMESECCVAIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAVCQNLQH-VLAVVRLQ MACMU8_150_PE9 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE18 ISOFORMIN FMESECCVVVAQ-ILQDLGDFVAAKRALKKAYRLGSQQPKQRHTICRNLKY-VLKVMSLK MONDO3_446_PE19 ENSMODG00000010893 FMESECCVVVAQ-ILQDLGDFVAAKRALKKAYRLGSQQPKQRHTICRNLKY-VLKVMSLK MOUSE15_PE693 NOISO FMESECCVLVSQ-VLQDLGDFLAAKRALKKAYRLGSQKPNQRVTVCQSLKY-VLAVIQLQ OCHPRGS_3363_PE1 NOISO FLESECCLLISQ-VLQDLGDFLAAKRALKKAFKLGSQKPSQGAVVLRSLKH-VLAVVQLQ ORYLA22_10_PE32 NOISO FIESECFHCIGKQVQLSLGDFVAARRSLKKALQLGSQQPQDRMAVKKAFKYAD-RGCKLE PANTR8_151_PE18 ENSPTRG00000020702 FMESECCVAIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQH-VLAVVRLQ PONPY8_158_PE43 NOISO FMESECCVAIAQ-VLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQH-VLAVVRLQ PROCAGS_4222_PE3 NOISO -----------------------------------------------------MKVVQLQ PTEVAGS_3119_PE5 NOISO FMESECCVLISQ-VLQDLGDFLAAKRVLKKACRLGFQKPLQKAAVHQTLKY-VLAVVRLQ RAT7_PE1316 NOISO FMESECCMLVSQ-VLQDLGDFLAAKRALKKAYRLGSQKPNQRVAICQSLKY-VLAVVRLQ TETNG10_PE412 NOISO YGESECFHCIGK-VQLSLGDFVAARRSLKKALLLGSQQNVDRQSVKKAFKYAD-RGCKLE TURTRGS_2770_PE5 NOISO SMESECCLLLSE-VLQDLGDFLAAKRALKKAYRLGSQKPLQKAVVCRTLKY-VLAVVRLQ XENTR8389_PE1 ISOFORMIN HMESECYSSIGQ-ALLTLGDLSAGKRSLKKSFLLGSRDLTDRDIVRRNLKYAI-RGCRLE XENTR8389_PE2 ENSXETG00000020475 HMESECYSSIGQ-ALLTLGDLSAGKRSLKKSFLLGSRDLTDRDIVRRNLKYAI-RGCRLE MATCH CONSENSUS ??ESEC???????????LGDF?AA?R?LKKA??LG?Q?????????????????????L?

AILMEGL192891_1_1_PE28 NOISO QQLQES-EGS-DPQGAMGICEQLGDLFS-----KAGDFPKAAEAYQKQLHFAELLGRPGP ANOCA949_PE5 NOISO QALEEA-EASCDRGAALALSEQLGDLFS-----KAGDYQRSLEAYKKQLGYAQALKRPPH BOVIN14_1_PE29 NOISO QRLEES-EES-DPEVAMGICEQLGDLFS-----KAGDFPKAAAAYQKQLRFAELLSRPGP CALJA16_53_PE31 ENSCJAG00000021411 QQLEEA-EGN-DPQGAMAICEQLGDLFS-----KAGDFPRAAEAYQKQLHFAELLDRPGA CALJA16_53_PE32 ISOFORMIN QQLEEA-EGN-DPQGAMAICEQLGDLFS-----KAGDFPRAAEAYQKQLHFAELLDRPGA CANFA13_42_PE31 NOISO RQLQES-EGS-DPQGAMAICEQLGDLFS-----KAGDFPKAAEAYQKQLHFAELLGRPGP CAVPO95_4_PE29 NOISO QQLEEA-ESS-DRQDAMAICEQLGDLFS-----KAGDFPKAAEAYQKQLYFAEQLNRPDP DANRE17_10_PE1 NOISO QTAAE--VTQKFSHEALDLSEQLGDLYC-----KVGCYSKALEAYQTQLACAEALAKPAR DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO QRLEEA-EGS-DPQGALAICEQLGDLFS-----KAGNFPKAAEAYQKQLRVAERLDRPDL ERIEUGS_7142_PE4 NOISO ------------------------------------------------------------ FELCAGS_5236_PE3 NOISO XXXXXX-XXX-XXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXLYFAELLSRPGP FUGRU10_1_PE41 ENSTRUG00000007494 EEFGDDQATGLSSHQAVGLAEQLGDLYC-----KVGCYSKALDAYQAQLKGAEALGKPAR GASACGROUPXV_8_PE3 ISOFORMIN EELGEDPVKGLGSHRAVGLAERLGDLYC-----KVGCYGKALDAYQAQLAGAEALGKPAR GASACGROUPXV_8_PE4 ENSGACG00000009209 EELGEDPVKGLGSHRAVGLAERLGDLYC-----KVGCYGKALDAYQAQLAGAEALGKPAR GORGO8_150_PE69 ENSGGOG00000016222 QQLEEA-EGS-DPQGAMVICEQLGDLFS-----KAGDFPRAAEAYQKQLRFAELLDRPGA GORGO8_150_PE70 ISOFORMIN QQLEEA-EGS-DPQGAMVICEQLGDLFS-----KAGDFPRAAEAYQKQLRFAELLDRPGA HORSE9_85_PE50 ENSECAG00000014231 QRLEEA-EGS-DPQGAMGICEQLGDLFS-----KAGDFPKAAKAYEKQLHFAELLNRPGP HORSE9_85_PE51 ISOFORMIN QRLEEA-EGS-DPQGAMGICEQLGDLFS-----KAGDFPKAAKAYEKQLHFAELLNRPGP HS8_PE3560 ENSG00000160949 QQLEEA-EGR-DPQGAMVICEQLGDLFS-----KAGDFPRAAEAYQKQLRFAELLDRPGA HS8_PE3561 ISOFORMIN QQLEEA-EGR-DPQGAMVICEQLGDLFS-----KAGDFPRAAEAYQKQLRFAELLDRPGA HS8_PE3562 ISOFORMIN QQLEEA-EGR-DPQGAMVICEQLGDLFS-----KAGDFPRAAEAYQKQLRFAELLDRPGA LOXAF185_PE10 ISOFORMIN ----------------------------------------------PQLHFAELLGRPGP LOXAF185_PE9 ENSLAFG00000027120 QQLEEA-KDC-DPESAMGICEQLGDLFS-----KAGDFPRAAKAYQKQLHFAELLGRPGP MACEUGS_6643_PE1 NOISO QKLEEA-EHS-DLHEALGICEQLGDLFS-----KSGDFPKAAEAYQKQLQFAKSLKIPTQ MACMU8_150_PE8 ENSMMUG00000002655 QQLEDA-EGS-DPQGAMAICEQLGDL---FSKA--GDFPRAAEAYQKQLRFAELLDRPGA MACMU8_150_PE9 ISOFORMIN --------GL-PEAG---VWPRLGGRPVRLARPGQGGSP-QPHWHCPQLRFAELLDRPGA MONDO3_446_PE18 ISOFORMIN QRLEEA-ESS-DLHGALSICEQLGDLFS-----KSGDFPKAVEAYQKQLQFAKSLKIPNQ MONDO3_446_PE19 ENSMODG00000010893 QRLEEA-ESS-DLHGALSICEQLGDLFS-----KSGDFPKAVEAYQKQLQFAKSLKIPNQ MOUSE15_PE693 NOISO QQLEEA-EGN-DLQGAMAICEQLGDLFS-----KAGDFPKAAEAYQKQLHLAELLNRPDL OCHPRGS_3363_PE1 NOISO QRLEEA-EGS-NPQDAMAICEQLGDLFS-----KAGDFPKAAQAYQKQLHLAELLQRPGP ORYLA22_10_PE32 NOISO EDLGEDQGKRLGPRQAVELAEQLGDLCC-----KVGCYSKAVDAYQAQLKGAEEMGKPAR PANTR8_151_PE18 ENSPTRG00000020702 QQLEEA-EGR-DPQGAMVICEQLGDLFS-----KAGDFPRAAEAYQKQLRFAELLDRPGA PONPY8_158_PE43 NOISO QQLEEA-EGS-DPQGAMAICEQLGDLFS-----KAGDFPRAAEAYQKQLRFAELLDRPGA PROCAGS_4222_PE3 NOISO QQLEET-KGR-DPESAVGICEKLGDLFS-----KAGDYPKAAEAYQKQLHFAELLGRPGP PTEVAGS_3119_PE5 NOISO QRLEES-EAS-DPQGAMGICEQLGDLFS-----KAGDFPKAAKAYQKQLQLAELLGRPGP RAT7_PE1316 NOISO QQLQEA-EGN-DLQGAMAICEQLGDLFS-----KADDFPKASEAYQKQLHFAELLNRPDL TETNG10_PE412 NOISO EELGEDQASRPSSHQAVGLAEQL-DLYC-----KVGCYSKALDAYQAQLKGAEALGKPAR TURTRGS_2770_PE5 NOISO QQLEES-EES-DPRGAMGICEQLGDLFS-----KAGDFPKAAAAYQKQLQFAELLNRPGP XENTR8389_PE1 ISOFORMIN ESLSE--LSEEDQQGALCLYEQLGDLYC-----KVGCYTRAIEDYRMQLNCAETLGRPER XENTR8389_PE2 ENSXETG00000020475 ESLSE--LSEEDQQGALCLYEQLGDLYC-----KVGCYTRAIEDYRMQLNCAETLGRPER MATCH CONSENSUS ??L?E??????????A????EQLGDL???????K?G????A??AY??QL??AE?L??P??

AILMEGL192891_1_1_PE28 NOISO ELAIIHVSLATTLGDMKDYRRAVSHYEQELRLRGGDALEEAKTWLNIALSREEAGDAYEL ANOCA949_PE5 NOISO ELAVIHVSLAATFGDLKDHAQALHHYQEELALRKGNLLEEGKTWLSIALAKEEAKESYEE BOVIN14_1_PE29 NOISO ELAVIHVSLAATLGDMKDHRQAVHHYEAELKLQEGNPLEEAKTWLNIALSREEAGDAYEV CALJA16_53_PE31 ENSCJAG00000021411 ERAIIHVSLATTLGDMKDHLGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL CALJA16_53_PE32 ISOFORMIN ERAIIHVSLATTLGDMKDHLGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL CANFA13_42_PE31 NOISO ELAIIHVSLATTLGDMKDHRRAVSHYEQELRLRGGDALEEAKTWLNIALSREEAGDAYEL CAVPO95_4_PE29 NOISO ELAIIHVSLATTLGDMKDHRQAVYHYEEELRLCKGNALEEAKTWLNIALSQEEAGDAYEL DANRE17_10_PE1 NOISO ELAVIHVSLAATYTDLRQHHRAVEHYRQELQLRKGNPKEECETWLNMAVCQEEMCQSMET DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO ELAIIHVSLATTLGDMKHR--QAVHYEEELRLRKGNALEEAKTWFNIAVSREEAGDAYEL ERIEUGS_7142_PE4 NOISO ---------ASIPGEIKDPQGAWHHYEEELRLRAGNAVEEAKTWLNIALSREEAGDAYEL FELCAGS_5236_PE3 NOISO ELAVIHVSLAATLGDMKDHRRAVSHYEQELRLRGGDALEEAKTWLNIALSREEAGDAYEL FUGRU10_1_PE41 ENSTRUG00000007494 ELAVIHVSLAETYTDLMQHSRAVEHYKRELALRQGSPAEECSTWLNVAAAQEEGGFPFED GASACGROUPXV_8_PE3 ISOFORMIN ELAVIHVSLAATYTDLRQHSKAVEHYRQELALRQGSPTEECGTWLNIAAAQEESGCSLEE GASACGROUPXV_8_PE4 ENSGACG00000009209 ELAVIHVSLAATYTDLRQHSKAVEHYRQELALRQGSPTEECGTWLNIAAAQEESGCSLEE GORGO8_150_PE69 ENSGGOG00000016222 ERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL GORGO8_150_PE70 ISOFORMIN ERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL HORSE9_85_PE50 ENSECAG00000014231 ELAVIHVSLAATLGDMKDHRRAVYHYEEELRLRDGNALEVRADGIQPCPAHTGEGGALEG HORSE9_85_PE51 ISOFORMIN ELAVIHVSLAATLGDMKDHRRAVYHYEEELRLRDGNALEGVATGAHPSCSRKAKTLEFTT HS8_PE3560 ENSG00000160949 ERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL HS8_PE3561 ISOFORMIN ERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL HS8_PE3562 ISOFORMIN ERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL LOXAF185_PE10 ISOFORMIN ELAVIHVSLATTWGDMKEPGRAVHHYEEELKLRSGNPLEEAKTWFNIALSREEAGDAYEL LOXAF185_PE9 ENSLAFG00000027120 ELAVIHVSLATTWGDMKEPGRAVHHYEEELKLRSGNPLEEAKTWFNIALSREEAGDAYEL MACEUGS_6643_PE1 NOISO ELAVIHVSLAATFGDLKNYSQAVEHYEEELRLQRGNPLEEAKTWLNIALSKEEAGKPYEE MACMU8_150_PE8 ENSMMUG00000002655 ERAIIHVSLAATLGDMKDHRGAVRHYEEELRLRSGNMLEEAKTWLNIALSREEAGDAYEL MACMU8_150_PE9 ISOFORMIN ERAIIHVSLAATLGDMKDHRGAVRHYEEELRLRSGNMLEEAKTWLNIALSREEAGDAYEL MONDO3_446_PE18 ISOFORMIN ELAVIHVSLAATFGDLKNYSQAVEHYEEELRLRRGNPLEEAKTWLNIALSKEEGGKPYEE MONDO3_446_PE19 ENSMODG00000010893 ELAVIHVSLAATFGDLKNYSQAVEHYEEELRLRRGNPLEEAKTWLNIALSKEEGGKPYEE MOUSE15_PE693 NOISO ELAVIHVSLATTLGDMKDHRKAVHHYEEELRLRKGNALEEAKTWFNIALSREEAGDAYEL OCHPRGS_3363_PE1 NOISO ELAVIHVSLATTLGDMKQYRQAEHHFQEELRLRNGNALEEAETWLNIALSREEAGDPYEV ORYLA22_10_PE32 NOISO ELAVIHVSLAATYTDLRRHGKAVEHYRKELALRQGNSVEECKTWLNIAASQEDSGCPLEG PANTR8_151_PE18 ENSPTRG00000020702 ERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL PONPY8_158_PE43 NOISO ERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYEL PROCAGS_4222_PE3 NOISO ELAVIHVSLATTWGDMKEPGRAVHHYEEELKLRSGNALEEAKTWYNIAVSREEAGGPYEL PTEVAGS_3119_PE5 NOISO ELAIIHVSLAATLGDMKDHRQAVHHYEEELRLRDGSALEEAKTWLNIALSREEAGDTYEE RAT7_PE1316 NOISO ELAVIHESLATTLGDMKDYHKAVHHYEEELRLRKGNALEEAKTWFNIGLAREEAGDAYEL TETNG10_PE412 NOISO ELAVIHVSLAATYTDLRQHGRAVEHYEQELALRQGSPAEDCSTWLNVAAAQEESGCPCEE TURTRGS_2770_PE5 NOISO ELAVIHVSLAATLGDMKDHRQAVRHYEEELRLRDGSALEEAKTWLNIALSREDAGDAYEV XENTR8389_PE1 ISOFORMIN ELAVIHVSLATTFTDLKDHVQAVKHYRAELELRKGNPSEECKTWMNIAQSYEEDGRRHTD XENTR8389_PE2 ENSXETG00000020475 ELAVIHVSLATTFTDLKDHVQAVKHYRAELELRKGNPSEECKTWMNIAQSYEEDGRRHTD MATCH CONSENSUS E?A?IHVSLA?T??D?K????AV?HY??EL?LR?G???EE??TW?NIA???EE?G???E?

AILMEGL192891_1_1_PE28 NOISO LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPV ANOCA949_PE5 NOISO LEPCFRKALQYAEKAFDPRLQHQ-ILQHLHACQQRAGRP-----------------EAAE BOVIN14_1_PE29 NOISO LALCFQKALGCAQLAGQPQLQRQ-ILQHLHAVQLRLQPQ-----------------EAPS CALJA16_53_PE31 ENSCJAG00000021411 LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRMQPQ-----------------EAPG CALJA16_53_PE32 ISOFORMIN LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRMQPQ-----------------EAPG CANFA13_42_PE31 NOISO LAPCFQKALGCAQQAQQPRLQRQ-VLRHLHTVQLRLQPQ-----------------EAPT CAVPO95_4_PE29 NOISO LAPCFQKALSCAQQAQQPQLQRQ-VLQHLHTVQLRLQPQ-----------------DAPG DANRE17_10_PE1 NOISO LDHCFASALNCAEKSGLNKLQRR-VLRVWLQAQRRCGSS-----------------QCDD DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO LAPCFQKAVSCAEQAQQPWLQRQ-VLQHLHAVQLRLQPQ-----------------EAPG ERIEUGS_7142_PE4 NOISO LAPCFQKALSCAQQAQRPQLQRQ-ILQHLHTVQLHLHPQ-----------------EAAS FELCAGS_5236_PE3 NOISO LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHSVQLRLQPQ-----------------EAPG FUGRU10_1_PE41 ENSTRUG00000007494 VHSSFSKASNCAQTSGQARLQKR-ALRIWLAFQRRRGPS-----------------VSGD GASACGROUPXV_8_PE3 ISOFORMIN IESSYGAAADCVQKAGQTRLQKR-ALRLWLAAQRRRGSS-----------------GAED GASACGROUPXV_8_PE4 ENSGACG00000009209 IESSYGAAADCVQKAGQTRLQKR-ALRLWLAAQRRRGSS-----------------GAED GORGO8_150_PE69 ENSGGOG00000016222 LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTMQLRLQPQ-----------------EAPE GORGO8_150_PE70 ISOFORMIN LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTMQLRLQPQ-----------------EAPE HORSE9_85_PE50 ENSECAG00000014231 PAHRLMTGGDSPSEEGQPMPVRQTEEGHVQGAGAVLGPS----------------GSAPP HORSE9_85_PE51 ISOFORMIN PMPALSQALDWSCQ---ARRERRRHTGCHSAAQHLLKPSRARSCMVSLMEGSAVQDSPSK HS8_PE3560 ENSG00000160949 LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPE HS8_PE3561 ISOFORMIN LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPE HS8_PE3562 ISOFORMIN LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPE LOXAF185_PE10 ISOFORMIN LAPCFQKALSCAQQAQQLRLQRR-ILQHFQVVQLRLQPQ-----------------EAPG LOXAF185_PE9 ENSLAFG00000027120 LAPCFQKALSCAQQAQQLRLQRR-ILQHFQVVQLRLQPQ-----------------EAPG MACEUGS_6643_PE1 NOISO LEPCFQSALHCSQEAKKPWLQRQ-VLQHLHAVQLKHQPL-----------------KAPS MACMU8_150_PE8 ENSMMUG00000002655 LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPG MACMU8_150_PE9 ISOFORMIN LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPG MONDO3_446_PE18 ISOFORMIN LEPCFQSALHCSQEAKKPWLQRQ-ILQHLHALQLKYQPH-----------------EAPN MONDO3_446_PE19 ENSMODG00000010893 LEPCFQSALHCSQEAKKPWLQRQ-ILQHLHALQLKYQPH-----------------EAPN MOUSE15_PE693 NOISO LAPCFQKAFCCAQQAQRFQLQRQ-ILQHLYTVQLKLQPQ-----------------EARD OCHPRGS_3363_PE1 NOISO LAPCFQKALGCAQEAQQPQLQRR-VLRLLHAVQLTLQPQ-----------------EAHA ORYLA22_10_PE32 NOISO VESSYSSALRCAQVAELKRLQKR-VLRLWLAYQRRSGAA-----------------TAGD PANTR8_151_PE18 ENSPTRG00000020702 LAPCFQKALSCAQQAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPE PONPY8_158_PE43 NOISO LAPCFQKALSCAQHAQRPQLQRQ-VLQHLHTVQLRLQPQ-----------------EAPD PROCAGS_4222_PE3 NOISO LAPCYQKALSCAQEAQQPWLQRR-ILQHLHTVQLRLQPQ-----------------EAPG PTEVAGS_3119_PE5 NOISO LAPCFQKALSCAQQAQQPQLQRQ-ILRHLHTVQLRLQHQ-----------------EAPG RAT7_PE1316 NOISO LAPCFQKAFGCAQQAQRYQLQRQ-ILQHLYTVQLKLQPQ-----------------EARD TETNG10_PE412 NOISO VDSSYTKASNCAQKSGQARLQKR-TLRLWLAFQRRHGVC-----------------LSKD TURTRGS_2770_PE5 NOISO LAPCFQKALSCAQQAQQPRLQRQ-VLRHLHAVQLRLQPQ-----------------EALG XENTR8389_PE1 ISOFORMIN IQSCLSNALQCAQRAGEAALQRK-VLRQLLAVQEKLGDP-----------------EVGD XENTR8389_PE2 ENSXETG00000020475 IQSCLSNALQCAQRAGEAALQRK-VLRQLLAVQEKLGDP-----------------EVGD MATCH CONSENSUS ???C???A??CAQ?A????LQR???L??????Q????????????????????????A??

AILMEGL192891_1_1_PE28 NOISO TAATLQELSVPRDQED---DDE---EEKEGDGDTPEASDVELSESEGDAEGRSQQLEEDE ANOCA949_PE5 NOISO TMGRLQDLRRMEGWHSDGEISE-EEEEEEESSEPLVESDLELSDSGKVTHGDFPDMLEDE BOVIN14_1_PE29 NOISO TETRLQELKAAGDE-D---EGDGEDEEDEEDDDALEATELELSESENEADAS-PPLEEDE CALJA16_53_PE31 ENSCJAG00000021411 TEIRLQELIVAEDEEE---EEE-EAAVATVDSGALEASEVELSESEDDTDGLTQQLEEDE CALJA16_53_PE32 ISOFORMIN TEIRLQELIV-----------------ATVDSGALEASEVELSESEDDTDGLTQQLEEDE CANFA13_42_PE31 NOISO TAARLQELSVPGDEEE---DEE---EEKEGDSDTPEASDVELSESEGDADGLSQQPEEDE CAVPO95_4_PE29 NOISO TESKLQELSVANEEEE---EEVEE-----EATEAVEIIELELSESEDDSDDPSREPEEHE DANRE17_10_PE1 NOISO TEARLMELCERDGLSLDQSEDED-EEDDVDNSEPLEDSDIQYSES-DD---------EDL DASNOGS_4799_PE2 NOISO ------------------------------------------------------------ DIPORGS_3810_PE3 NOISO TETKLQELSVAEGEEE---EEEEEAE----AGEALDTSELELSESEDDTTSLSRPL-EDE ERIEUGS_7142_PE4 NOISO TEAKLQELSRSGEEEE---EEEEEEAEKEGDADVLEPSEVELSESEEEANGWSPQRDEEE FELCAGS_5236_PE3 NOISO TEARLQELSVPRDQEE---DED---KEEEGDGDTPEASDVELSESEGDAEGWSQQPEEDE FUGRU10_1_PE41 ENSTRUG00000007494 TEAKLQELCAAEGWNPDGSDGED-DEEEMDNSEPLDDSDVILSES-D----------DDL GASACGROUPXV_8_PE3 ISOFORMIN TEARLQELCAAEGWCPDGSDGEGDEEEEMDNSEPLDDSDVVLSDS-D----------DDL GASACGROUPXV_8_PE4 ENSGACG00000009209 TEARLQELCAAEGWCPDGSDGEGDEEEEMDNSEPLDDSDVVLSDS-D----------DDL GORGO8_150_PE69 ENSGGOG00000016222 TETRLRELSVAEDEDE---EEEAEEAAATAESEALEAGEVELSESEDDADGLTPQLEEDE GORGO8_150_PE70 ISOFORMIN TETRLRELSVAEDEDE---EEEAEEAAATAESEALEAGEVELSESEDDADGLTPQLEEDE HORSE9_85_PE50 ENSECAG00000014231 KTLESQELVHKSSSEE---WDW-AENSWEELDADKRARSVQLQAWEGRALGS-PGDEMEE HORSE9_85_PE51 ISOFORMIN RSLWRERTESKSSSEE---WDW-AENSWEELDADKRARSVQ----------------MEE HS8_PE3560 ENSG00000160949 TETRLRELSVAEDEDE---EEEAEEAAATAESEALEAGEVELSEGEDDTDGLTPQLEEDE HS8_PE3561 ISOFORMIN TETRLRELSVAEDEDE---EEEAEEAAATAESEALEAGEVELSEGEDDTDGLTPQLEEDE HS8_PE3562 ISOFORMIN TETRLRELSVAEDEDE---EEEAEEAAATAESEALEAGEVELSEGEDDTDGLTPQLEEDE LOXAF185_PE10 ISOFORMIN TEARLQELDVDSQALE---ASE-----VELS-------ESAHTDTENEN------PEEDE LOXAF185_PE9 ENSLAFG00000027120 TEARLQELDVASQALE---ASE-----VELS-------E-----SENEN------PEEDE MACEUGS_6643_PE1 NOISO TNSKLQELSCAEGWSPSKDIMEEEEEEELENSEALEDSEVELSESENEDGGNLQSGEEEM MACMU8_150_PE8 ENSMMUG00000002655 TETRLQELSVDEDEDE---EE---EAAATAECKALEASEVELSESEDDADGLTPQLEEDE MACMU8_150_PE9 ISOFORMIN TETRLQELSVDEDEDE---EE---EAAATAECKALEASEVELSESEDDADGLTPQLEEDE MONDO3_446_PE18 ISOFORMIN TSSKLQELSSTEDGSPSKDISEEDEEEELENSEALEDSEVELSEK-NEDNDSLQPGEEEM MONDO3_446_PE19 ENSMODG00000010893 TSSKLQELSSTEDGSPSKDISEEDEEEELENSEALEDSEVELSEK-NEDNDSLQPGEEEM MOUSE15_PE693 NOISO TEIRLQELSMAKDTEE---EEEEEEEEEEEASEAPETSELELSESEDDADGLSQQLEEDE OCHPRGS_3363_PE1 NOISO TELRLQELGVAEDEEE---EEEEE---EAVASRALEDSEPDLSESEDDVDSRSQQ--EDE ORYLA22_10_PE32 NOISO TEARLQELCASEGWNPDGSDGEEEDEEEMDNSEPLDDSDVLLSDS-D----------EDL PANTR8_151_PE18 ENSPTRG00000020702 TETRLRELSVAEDEDE---EEEAEEAAATAESEALEAGEVELSESEDDADGLTPQLEEDE PONPY8_158_PE43 NOISO TETRLRELGVAEGEDE---EEEAEEAAATAESEALEAGEVELSESEDDADGLTPQLEEDE PROCAGS_4222_PE3 NOISO TEARLQELCVAGDGEE---EEE-----EEEDSEALEDSEMELSESENEA------P-EEG PTEVAGS_3119_PE5 NOISO TEARLQELGEGEDEGE---D------DGGEDSDAVEASEVELSDSDDEADSQ-SQ-RLQD RAT7_PE1316 NOISO TEIRLQELSMAKDTEE---EEEEEEEEEEEASEALETSEMELSESEDDADGLSQQLEEEE TETNG10_PE412 NOISO TEAKLLELCAAEGWNPDGSDGED-EEEEMDNSEPLEDSDVVLSDS-D----------DDL TURTRGS_2770_PE5 NOISO TEARLQELRAAEDEED---EGDEDDEDDEGESAALEAIEVELSESEDEVDGS-QRLE-EE XENTR8389_PE1 ISOFORMIN TEAKLQELCSGPGGE------SSEEEEEMENSEPLQESDLELSQSEDD---------EDL XENTR8389_PE2 ENSXETG00000020475 TEAKLQELCSGPGGE------SSEEEEEMENSEPLQESDLELSQSEDD---------EDL MATCH CONSENSUS T???L?EL?????????????????????????????????LS?????????????????

AILMEGL192891_1_1_PE28 NOISO EL--QGCLGQQRVNKWNRRNDVGETLLHRACIEGRLGRVQDLVRQG----HPLNPRDYCG ANOCA949_PE5 NOISO EF--DGFQKRRKGDNWNQRNDKGETLLHRACIDGNLRRVQFFVEKG----HPLNPRDYCG BOVIN14_1_PE29 NOISO EL--RGCLGRQRVNKWSRRNDVGETLLHRACIEGQLGRVQDLVRQG----HPLNPRDYCG CALJA16_53_PE31 ENSCJAG00000021411 EL--QGRLGQRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG-----HPNPRDYC- CALJA16_53_PE32 ISOFORMIN EL--QGRLGQRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQVVVTGPPQNPRDYC- CANFA13_42_PE31 NOISO EL--QGCLGQRRASKWNRRNDVGETLLHRACIEGRLARVQDLVRQG----HPLNPRDYCG CAVPO95_4_PE29 NOISO ER--QACLGRRKVNKWNRRNDMGETLLHRACIEGRLRRVQDLVKQG----HPLNPRDYCG DANRE17_10_PE1 NOISO EGYDKMVTGRRKTQRWNRRNEKGETVLHRACIEGNLRQVQYLIEQG----HPVNVRDYCG DASNOGS_4799_PE2 NOISO -------------------------------------------------GHPLNPRDYCG DIPORGS_3810_PE3 NOISO EL--QGYLGRRQVNKWNQRNDLGETLLHRACIEGHLRRVQDLVRRG----HPLNPRDYCG ERIEUGS_7142_PE4 NOISO P-----RGPRRKVDRWNRRNDVGETLLHRACIEGQLGRVQDLVRQG----HPLNPRDHCG FELCAGS_5236_PE3 NOISO EL--RACLGRQTVNKWNRRNDVGETLLHRACIEGRLGRVQDLVRQG----HPLNPRDYCG FUGRU10_1_PE41 ENSTRUG00000007494 EGYDKMVTGRRKTGRWNKRNEKGETSLHRACIDGNLKQVQYLVEQG----HPINPRDYCG GASACGROUPXV_8_PE3 ISOFORMIN EGYDKMVSGRRKAGRWNKRNEKGETTLHRACIDGNLKQVQYLVEQG----HPVNPRDNCG GASACGROUPXV_8_PE4 ENSGACG00000009209 EGYDKMVSGRRKAGRWNKRNEKGETTLHRACIDGNLKQVQYLVEQG----HPVNPRDNCG GORGO8_150_PE69 ENSGGOG00000016222 EL--QGHLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVKQG----HPLNPRDYCG GORGO8_150_PE70 ISOFORMIN EL--QGHLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVKQG----HPLNPRDYCG HORSE9_85_PE50 ENSECAG00000014231 EL--QSCRGRRRVTEWSRRNDVGETMLHRACIEGQLGRVQDLVRQG----HPLNPRDYCG HORSE9_85_PE51 ISOFORMIN EL--QSCRGRRRVTEWSRRNDVGETMLHRACIEGQLGRVQDLVRQG----HPLNPRDYCG HS8_PE3560 ENSG00000160949 EL--QGHLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG----HPLNPRDYCG HS8_PE3561 ISOFORMIN EL--QGHLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG----HPLNPRDYCG HS8_PE3562 ISOFORMIN EL--QGHLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG----HPLNPRDYCG LOXAF185_PE10 ISOFORMIN EL--RGCLGQQKMNKWNRRNDMGETLLHRACIEGQLRRIQDLVKQG----HPVNPRDYCG LOXAF185_PE9 ENSLAFG00000027120 EL--RGCLGQQKMNKWNRRNDMGETLLHRACIEGQLRRIQDLVKQG----HPVNPRDYCG MACEUGS_6643_PE1 NOISO ESYGQTGPGRRKVNKWNRRNDMGETMLHRACIDGQQRRVRDLVEQG----HPLNPRDYCG MACMU8_150_PE8 ENSMMUG00000002655 EL--QGCPGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG----HPLNPRDYCG MACMU8_150_PE9 ISOFORMIN EL--QGCPGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG----HPLNPRDYCG MONDO3_446_PE18 ISOFORMIN ESYGQTGPGRRKVNKWNRRNDMGETMLHRACIDGQQRRVRDLVEQG----HPLNPRDYCG MONDO3_446_PE19 ENSMODG00000010893 ESYGQTGPGRRKVNKWNRRNDMGETMLHRACIDGQQRRVRDLVEQG----HPLNPRDYCG MOUSE15_PE693 NOISO EL--QGCVGRRKVNKWNRRNDMGETLLHRACIEGQLRRVQDLVKQG----HPLNPRDYCG OCHPRGS_3363_PE1 NOISO EL--RGCLGRQKRDKWNRRNDMGETLLHRACIEGQLRRVQYLVKQG----HPVNPRDYCG ORYLA22_10_PE32 NOISO EGYEKMVSGKRRTGRWNKRNEKGETSLHRACIDGNLKQVQYLIEQG----HPVNPRDYCG PANTR8_151_PE18 ENSPTRG00000020702 EL--QGHLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG----HPLNPRDYCG PONPY8_158_PE43 NOISO EL--QGRLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQG----HPLNPRDYCG PROCAGS_4222_PE3 NOISO EL--RGCLGQRKGNKWNRRNDVGETPLHRACIEGQLRRVQGLVKQG----HPVNPRDYCG PTEVAGS_3119_PE5 NOISO EL--HGGLGRQRTGKWHRRNDVGETLLHRACIEGQLGRVQDLVRQG----HPLNPRDYCG RAT7_PE1316 NOISO EL--QGCVGRRKINKWNRRNDMGETLLHRACIEGQLRRVQDLVKQG----HPLNPRDYCG TETNG10_PE412 NOISO EGYDKMVSGRRKTGRWNKRNEKGETSLHRACIDGNLKQVQYLVEQG----HPVNPRDYCG TURTRGS_2770_PE5 NOISO EL--QGCLGRRRVSKWNRRNDVGETLLHRACIEGQLGRVQDLVRQG----HPLNPRDYCG XENTR8389_PE1 ISOFORMIN EGYEKLVPGKRRVNRWNRRNEKGETVLHRACIEGNAKLVKTLIEKG----HPLSPRDYCG XENTR8389_PE2 ENSXETG00000020475 EGYEKLVPGKRRVNRWNRRNEKGETVLHRACIEGNAKLVKTLIEKG----HPLSPRDYCG MATCH . ** * CONSENSUS E???????G?R????WNRRN??GET?LHRACI?G?L??VQ?LV?QG????HP?NPRDYCG

AILMEGL192891_1_1_PE28 NOISO WTPLHEACNYGHLDIVRFLLDHGAVVDDPGGPGCEGITPLHDALHCGHFEVAELLIERGA ANOCA949_PE5 NOISO WTPLHEACNHGHLEVVRLLLDHGAAVDDAGGPGCEGITPLHDALNCGHFDVAEMLVQRGA BOVIN14_1_PE29 NOISO WTPLHEACNYGHLDIVRFLLDHGAAVDDPGGQGCDGITPLHDALNCGHFEVAELLIERGA CALJA16_53_PE31 ENSCJAG00000021411 WTPLHEACNYGHLEIVRFLLDHGATVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA CALJA16_53_PE32 ISOFORMIN WTPLHEACNYGHLEIVRFLLDHGATVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA CANFA13_42_PE31 NOISO WTPLHEACNYGHLDIVRFLLDHGAVVDDPGGEGCEGITPLHDALTCGHFEVAELLIGRGA CAVPO95_4_PE29 NOISO WTPLHEACNYGHLEIVRFLLDHGASVDDPGGQGCEGITPLHDALTCGHFEVAELLIERGA DANRE17_10_PE1 NOISO WTPLHESCNYGHQEIVAFLLDRGANVNDPGGRECGGITPLHDTLNCGHFSVARLLVLRGA DASNOGS_4799_PE2 NOISO WTPLHEACNHGHWEIVRFLLDHGAAVDDPGGPGCEGLTPLHDALTCGHFEVAELLIERGA DIPORGS_3810_PE3 NOISO WTPLHEACNYGHLEIVRFLLDHGAAVNDPGGQGCDGITPLHDALNCGHFEVAELLIQRGA ERIEUGS_7142_PE4 NOISO WTPLHEACNYGHLEIVHFLLDHGASVDDPGGQGCEGITPLHDALNCGHFEVAELLIKRGA FELCAGS_5236_PE3 NOISO WTPLHEACNYGHLDIVRFLLDHGAVVDDPGGQGCEGITPLHDALNCGHFEVAELLIERGA FUGRU10_1_PE41 ENSTRUG00000007494 WTPLHEASNHGHYDIVAVLLDHGANINDTGGPLCEGVTPLHDALSCGNFKVAQILVERGA GASACGROUPXV_8_PE3 ISOFORMIN WTPLHEACNHGHYDIVSVLLEYGANINDPGGPSCEGVTPLHDALSCGHFTVARLLVERGA GASACGROUPXV_8_PE4 ENSGACG00000009209 WTPLHEACNHGHYDIVSVLLEYGANINDPGGPSCEGVTPLHDALSCGHFTVARLLVERGA GORGO8_150_PE69 ENSGGOG00000016222 WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA GORGO8_150_PE70 ISOFORMIN WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA HORSE9_85_PE50 ENSECAG00000014231 WTPLHEACNYGHLDIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLIERGA HORSE9_85_PE51 ISOFORMIN WTPLHEACNYGHLDIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLIERGA HS8_PE3560 ENSG00000160949 WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA HS8_PE3561 ISOFORMIN WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA HS8_PE3562 ISOFORMIN WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA LOXAF185_PE10 ISOFORMIN WTPLHEACNHGHLEIVRFLLDHGATVDDPGGSGCEGITPLHDALTCGHFEVAELLIERGA LOXAF185_PE9 ENSLAFG00000027120 WTPLHEACNHGHLEIVRFLLDHGATVDDPGGSGCEGITPLHDALTCGHFEVAELLIERGA MACEUGS_6643_PE1 NOISO WTPLHEACNHGHLEIVRFLLDHGAAVDDPGGPGCEGITPLHDALNCGHFEVAELLIERGA MACMU8_150_PE8 ENSMMUG00000002655 WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA MACMU8_150_PE9 ISOFORMIN WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA MONDO3_446_PE18 ISOFORMIN WTPLHEACNHGHLEIVRFLLDHGAAVDDPGGPGCEGITPLHDALNCGHFEVAELLVERGA MONDO3_446_PE19 ENSMODG00000010893 WTPLHEACNHGHLEIVRFLLDHGAAVDDPGGPGCEGITPLHDALNCGHFEVAELLVERGA MOUSE15_PE693 NOISO WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCDGITPLHDALNCGHFEVAELLIERGA OCHPRGS_3363_PE1 NOISO WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAALLIEQGA ORYLA22_10_PE32 NOISO WTPLHEACNHGHYDVVAVLLERGANINDAGGPLCEGVTPLHDALTCGNFRVARLLVERGA PANTR8_151_PE18 ENSPTRG00000020702 WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA PONPY8_158_PE43 NOISO WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGA PROCAGS_4222_PE3 NOISO WTPLHEACNHGHLEIVRFLLDHGATVDDPGGPGCEGITPLHDALTCGHFEVAELLIKRGA PTEVAGS_3119_PE5 NOISO WTPLHEACNYGHLDIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLIERGA RAT7_PE1316 NOISO WTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCDGITPLHDALNCGHFEVAELLIERGA TETNG10_PE412 NOISO WTPLHEASNHGHHEIVAVLLGHGANVNDAGGPLCEGVTPLHDALSCGNFKVAQLLVERGA TURTRGS_2770_PE5 NOISO WTPLHEACNYGHLDIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAQLLIERGA XENTR8389_PE1 ISOFORMIN WTPLHEAANHGHLEIVELLLEKGANINDPGGPLCEGITPLHDALSSGNFHVAQLLIRRGA XENTR8389_PE2 ENSXETG00000020475 WTPLHEAANHGHLEIVELLLEKGANINDPGGPLCEGITPLHDALSSGNFHVAQLLIRRGA MATCH ******:.*:** ::* .** ** ::*.** * *:*****:* .*:* ** :*: :** CONSENSUS WTPLHEACN?GHL?IV?FLLDHGA?V?DPGG?GCEGITPLHDAL?CGHF?VA?LL?ERGA

AILMEGL192891_1_1_PE28 NOISO SVTLRTMKGHSPLETLQQWVKLYGKDLDSETREKAGSMESLLRAAS---S--GQAPHS-- ANOCA949_PE5 NOISO STLLRDGKGQTPLDTLHQWMHLYGRDLDQETRERCKAMEGLLKKAM---A--GRAKHSQL BOVIN14_1_PE29 NOISO SVTLRTRKGHNPLETLQQWVKLYGKDLDSETQEKAAAMGRLLQAAS---L--GRAPHS-- CALJA16_53_PE31 ENSCJAG00000021411 SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAT---S--GQGKQDPH CALJA16_53_PE32 ISOFORMIN SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAT---S--G---QDPH CANFA13_42_PE31 NOISO SVTLRTSKGHSPLETLQQWVKLYGRDLDSETREKAGAMERLLRAAA---A--GQAP---- CAVPO95_4_PE29 NOISO SVTLQTKKGHSPLETLQNWVKLYCKDLDLETRQKAAAMERRLQAAS---L--GPASSS-- DANRE17_10_PE1 NOISO SVTVRNSKGHTPLDTLRQWFKTYSGQLDPETKQECLETEKLIKRALS-----GDVSVV-- DASNOGS_4799_PE2 NOISO SVSLRTSKGHSPLETLQQWVKLYDEDLDQETRQKAAAMERLLRTAS---T--GQAL---- DIPORGS_3810_PE3 NOISO SVTLRTKKGHSPLETLQHWVKLYQRDLDLETRQKAAAMQRKLQAAS---S--GSAPD--- ERIEUGS_7142_PE4 NOISO SVTLRTKKGLSPLETLQQWVQLYRKDLDYDTQAKARAMERLLRATSSDPG--KQGS---- FELCAGS_5236_PE3 NOISO SVTLRTTKGHSPLETLQQWVRLYGKDLDSETREKAGAMERLLRAAP---S--GRAPHG-- FUGRU10_1_PE41 ENSTRUG00000007494 SVTLHNSKGYTALDTLHQWQRTYRRELDQEARQACITTERLLRKALA-----GGVSAA-- GASACGROUPXV_8_PE3 ISOFORMIN SVT---QRGETVMDTLHKWQRTYRRELDEDTKQECVTTEAVLRKALA-----GGVTAA-- GASACGROUPXV_8_PE4 ENSGACG00000009209 SVT---QRGETVMDTLHKWQRTYRRELDEDTKQECVTTEAVLRKALA-----GGVTAA-- GORGO8_150_PE69 ENSGGOG00000016222 SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAA---S--GQDPH--- GORGO8_150_PE70 ISOFORMIN SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAA---S--GQDPH--- HORSE9_85_PE50 ENSECAG00000014231 SVTLRTRKGYSPLETLQQWVKLYYKDLDSETREKAGAMERLLQPHSQFCL--PTAPHS-- HORSE9_85_PE51 ISOFORMIN SVTLRTRKGYSPLETLQQWVKLYYKDLDSETREKAGAMERLLQVASLGQG--KQGP---- HS8_PE3560 ENSG00000160949 SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAA---S--GQDPH--- HS8_PE3561 ISOFORMIN SVTLRTRKASARWRRC-SSGKLYRRDLDLETRQKARAMEMLLQAAA---S--GQDPH--- HS8_PE3562 ISOFORMIN SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAA---S--GQDPH--- LOXAF185_PE10 ISOFORMIN SVTLRTTKGHSPLETLQEWVRLYSRDLDQETWQKAGAMERLLQTAA---A--GQAPQG-- LOXAF185_PE9 ENSLAFG00000027120 SVTLRTTKGHSPLETLQEWVRLYSRDLDQETWQKAGAMERLLQTAA---A--GQAPQG-- MACEUGS_6643_PE1 NOISO SVTACTRRGHSPRETLRQWIKLYGRDLDQETRQKAQAMEKLLQTA-----SLGQASQ--- MACMU8_150_PE8 ENSMMUG00000002655 SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAA---S--GQGKQGLP MACMU8_150_PE9 ISOFORMIN SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAA---S--GQGKQGLP MONDO3_446_PE18 ISOFORMIN SVTAKNSKGHNPRETLRQWVKLYSKDLDQETRQKAQDMEKLLLQTARQ-----QASQ--- MONDO3_446_PE19 ENSMODG00000010893 SVTAKNSKGHNPRETLRQWVKLYSKDLDQETRQKAQDMEKLLLQTAPFSNRFPWASQ--- MOUSE15_PE693 NOISO SVTLRTRKGLSPLETLQQWVKLYFRDLDLETRQKAATMEKRLQMAS---S--GQASRS-- OCHPRGS_3363_PE1 NOISO SVTLRTRKGHSPLETLQQWVKLYCRELDLETRQKAAATERLLQATA---A--GRGCHA-- ORYLA22_10_PE32 NOISO AVTLQNSKGETALDTLRKWQRTYSRELDDDTRQECAATEKLLRKALA-----GGA--A-- PANTR8_151_PE18 ENSPTRG00000020702 SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAVEMLLQAAA---S--GQDPH--- PONPY8_158_PE43 NOISO SVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAA---S--GQDPH--- PROCAGS_4222_PE3 NOISO SVTLQTAKGHSPLETLQWWVRLYSRDLDQETWQKACAMERLLQTVA---A--GRDPQG-- PTEVAGS_3119_PE5 NOISO SVTLRTRKGHSPLETLQQWVKLYCQDLDSETWEKAGAMERLLQAAS---T--GRAPHS-- RAT7_PE1316 NOISO SVTLRTRKGLSPLETLQQWVKLYFRDLDLETRQKAASMERRLQMAS---S--GQASHS-- TETNG10_PE412 NOISO AVTLQNSKGYTALDTLHQWQRMYSGELDQEARQDCVATEKLLRRALA-----GGGPAA-- TURTRGS_2770_PE5 NOISO SVTLRTRKGRSPLETLQQWVKLYCKDLDGETREKAAAMETLLQAAS---S--GQAPHS-- XENTR8389_PE1 ISOFORMIN SVTLKNAKGVAPLGSLQDWIGTYGKHLDQETRQNCKETESLLREALA-----GRVAAA-- XENTR8389_PE2 ENSXETG00000020475 SVTLKNAKGVAPLGSLQDWIGTYGKHLDQETRQNCKETESLLREALA-----GRVAAA-- MATCH :. :. * .** :: . : CONSENSUS SVTL???KG??PL?TL??W??LY???LD?ET???????E?LL??A???????G???????

AILMEGL192891_1_1_PE28 NOISO ----SLAPHILPRNHLFDPEISPPSSPCPGPP-------ETSQARAGV------SPGQAV ANOCA949_PE5 NOISO L---KNINNAYLFPHSFTLSPSPPFNPFLSFSFFV----------KCVVHKQISSFVSSV BOVIN14_1_PE29 NOISO ----SQAPQTLPSNHLFDPETSPPSSPCPGTP-------EVCEASTRV------SQGLAV CALJA16_53_PE31 ENSCJAG00000021411 S---SQASRTIPSSLLFDPETSPPLSPCPEPPSNTTRPPEASQARARV------SLGQVA CALJA16_53_PE32 ISOFORMIN S---SQASRTIPSSLLFDPETSPPLSPCPEPPSNTTRPPEASQARARV------SLGQVA CANFA13_42_PE31 NOISO --------HGLPRSHLFDPEISPPLSPCPGSP-------EP------------------- CAVPO95_4_PE29 NOISO ----TPGPRTVLSNHLFDPEISPPLSPCFKP--------LASPAHTRI------SLKQTA DANRE17_10_PE1 NOISO -CAAPRQQKELQDSQLFDAEYSEPLLRESPPSPPPITRPAATVPT----SKDS-APKHRS DASNOGS_4799_PE2 NOISO --PSPQAPGTVPRSHLFDPEVSPPLSPHPGPSSDASRPLEASLEQA-------------- DIPORGS_3810_PE3 NOISO ----GSLTSHVPSDHLFDPEISPPSSPCLCIPR----PAEAPLVPSRV------SPEQVT ERIEUGS_7142_PE4 NOISO ACPSSLNAQTFPSNHLFDSETSPPSSPCPSP--------GASQACARA------SWEQVA FELCAGS_5236_PE3 NOISO ----SQAPHALPRNQLFDPEVSPPSSPCPGPP-------ETSQARARV------SLGQTV FUGRU10_1_PE41 ENSTRUG00000007494 -PAPVTPFDALQDSQLFDAENSEPLSASGGDGSSSTCQSQTVAEQWLHAAAQAERNRERC GASACGROUPXV_8_PE3 ISOFORMIN -PTPAKAFGALQDSQLFDAEMSEPLLSSGTGCPSSQDRPRTNRS----------TEVKAA GASACGROUPXV_8_PE4 ENSGACG00000009209 -PTPAKAFGALQDSQLFDAEMSEPLLSSGTGCPSSQDRPRTNRS----------TEVKAA GORGO8_150_PE69 ENSGGOG00000016222 ----SSQAFHAPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHARV------SPGQAA GORGO8_150_PE70 ISOFORMIN ----SSQAFHAPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHARV------SPGQAA HORSE9_85_PE50 ENSECAG00000014231 ----SLAPQTFLSNHLFDPETSPPSSPCPEPP-------ETSQASARV------SQGQAV HORSE9_85_PE51 ISOFORMIN ----LTPRDTFLSNHLFDPETSPPSSPCPEPP-------ETSQASARV------SQGQAV HS8_PE3560 ENSG00000160949 ----SSQAFHTPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHVRV------SPGQAA HS8_PE3561 ISOFORMIN ----SSQAFHTPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHVRV------SPGQAA HS8_PE3562 ISOFORMIN ----SSQAFHTPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHVRV------SPGQAA LOXAF185_PE10 ISOFORMIN ----SQVPQAFPSNPLFDPETSPPSSPCPGSPSCDLRPSEASKACARL------SPRQAA LOXAF185_PE9 ENSLAFG00000027120 ----SQVPQAFPSNPLFDPETSPPSSPCPGSPSCDLRPSEASKACARL------SPRQAA MACEUGS_6643_PE1 NOISO ---GSLTSQTIQTNSLFDPETSPSSSPSGLPPGHIRA----PASXXXXXXXX-XXXXXXX MACMU8_150_PE8 ENSMMUG00000002655 HPHSSQDSLTIPSSLLFDPETSPPLSPCPKPPSNSTRPPEASQARARV------SPGQAA MACMU8_150_PE9 ISOFORMIN HPHSSQDSLTIPSSLLFDPETSPPLSPCPKPPSNSTRPPEASQARARV------SPGQAA MONDO3_446_PE18 ISOFORMIN ---GSHTPQTIQTNPLFDPETSPTSSPIRSSHFLATSKAQHPFAQNRSFNKPLTSPELGG MONDO3_446_PE19 ENSMODG00000010893 ---GSHTPQTIQTNPLFDPETSPTSSPIRSSHFLATSKAQHPFAQNRSFNKPLTSPELGG MOUSE15_PE693 NOISO ----SPALQTIPSNHLFDPETSPPSSPCPEPSSYTPRPPEASPAPAKV------FLEETV OCHPRGS_3363_PE1 NOISO ---------GGAQNSLFDPEMSPPSSPLPESPSGTPAPSEASQACTGG------SPRRDV ORYLA22_10_PE32 NOISO -PAPAKPFDALQDSQLFDAENSEPLSASRGSCSSSQDCSRTGRA---------------V PANTR8_151_PE18 ENSPTRG00000020702 ----SSQAFHTPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHVRV------SPGQAA PONPY8_158_PE43 NOISO ----SSQAFRTPSSLLFDPETSPPLSPCPEPPSNSTRPPEASQAHARV------SPGQAA PROCAGS_4222_PE3 NOISO ----SQAPQAFPSTPLFDPETSPPLSPCPRP-------PEASQACTRP------SSRRAA PTEVAGS_3119_PE5 NOISO ----PLASEALLRDHLFDPEASPSSSPCPGPP-------EACQARARV------SQASAV RAT7_PE1316 NOISO ----SPALQTIPNNHLFDPETSPPSSPCPKPPSYTPRPPEASPAPAKV------FLEETV TETNG10_PE412 NOISO -PAPARPFDTLQDSQLFDAENSEPLPASGGAASSSQ--------DWLQNNRDGV----TA TURTRGS_2770_PE5 NOISO ----SLAPPTVPSNHVFDPETSPPSSPSPGPP-------EACQARARV------SQGLAV XENTR8389_PE1 ISOFORMIN -PSRP---ESLQDSELFDAEGSQPDSLAPSWDS-RADPQRTV------------------ XENTR8389_PE2 ENSXETG00000020475 -PSRP---ESLQDSELFDAEGSQPDSLAPSWDS-RADPLEEEQDDFVDT---------SP MATCH * . * . CONSENSUS ???????????????LFD?E?SPP?SP?????????????????????????????????

AILMEGL192891_1_1_PE28 NOISO PAA-------------ARPRRT-RHNLASSS--SSEGEDNPGPPRPVQKRPRHYVPAQQA ANOCA949_PE5 NOISO LAA-------------SKTQVQ-RETPSSQLFDAEFSESQGSGRHPARDRARWTLS-WTR BOVIN14_1_PE29 NOISO STV-------------ARPRRS-RHKVASSS--SSEGEDSAGPSQPTQKRPRHASPSLQT CALJA16_53_PE31 ENSCJAG00000021411 PAV-------------ARPRRS-RHGPASSS--SSEGEDSTGTPQPSQKRPRCSATAQQV CALJA16_53_PE32 ISOFORMIN PAV-------------ARPRRS-RHGPASSS--SSEGEDSTGTPQPSQKRPRCSATAQQV CANFA13_42_PE31 NOISO -PG-------------ARPWRN-RHTLASSS--SSEGEDG--PARPTPKRPRHSVPAQQV CAVPO95_4_PE29 NOISO SAV-------------ARPRRS-RHRLS-------DSENTVSPHGPSQKRLRRSAMAQQD DANRE17_10_PE1 NOISO TSASTRWPRGM-----EVDVL---YGDDSSSSDNPDSDCSLSPLRPVRSRPRSPP--AQS DASNOGS_4799_PE2 NOISO --A-------------ARPPGD-RSAAASG---SHSEGDCGGPLGPVQKRPRLSAAAPQA DIPORGS_3810_PE3 NOISO PAV-------------ARPRKG-RHRPASSSSSSSEDEDCVGTLRPSQKKHRASGVM--W ERIEUGS_7142_PE4 NOISO GAP-------------PRPRRS-WQELVGSS--SSEGEDNTDPPRPAQKRHRTS--AQQA FELCAGS_5236_PE3 NOISO PAV-------------TRPRRS-RHKLASSS--SSEGEDNPGPPRPNQKRPRHSVQPQQD FUGRU10_1_PE41 ENSTRUG00000007494 PISSSDSSDSDRSVSPLRPVRPRK-SFSATSQK--------------------ELPPNAD GASACGROUPXV_8_PE3 ISOFORMIN PASPTRWKSN----GSATRHRARNQSS---SSEDSDSDCPPA--APSQKEAPA---HR-E GASACGROUPXV_8_PE4 ENSGACG00000009209 PASPTRWKSN----GSATRHRARNQSS---SSEDSDSDCPPA--APSQKEAPA---HR-E GORGO8_150_PE69 ENSGGOG00000016222 PAM-------------ARPRRS-RHGPASSSS-STEGEDSAGSARPSQKRPRCSATAQRV GORGO8_150_PE70 ISOFORMIN PAM-------------ARPRRS-RHGPASSSS-STEGEDSAGSARPSQKRPRCSATAQRV HORSE9_85_PE50 ENSECAG00000014231 PAV-------------ARPRRS-RHELASSS--SSEGEDSMGFPQPIQKRPRHSAPAQQT HORSE9_85_PE51 ISOFORMIN PAV-------------ARPRRS-RHELASSS--SSEGEDSMGFPQPIQKRPRHSAPAQQT HS8_PE3560 ENSG00000160949 PAM-------------ARPRRS-RHGPASSSS-SSEGEDSAGPARPSQKRPRCSATAQRV HS8_PE3561 ISOFORMIN PAM-------------ARPRRS-RHGPASSSS-SSEGEDSAGPARPSQKRPRCSATAQRV HS8_PE3562 ISOFORMIN PAM-------------ARPRRS-RHGPASSSS-SSEGEDSAGPARPSQKRPRCSATAQRV LOXAF185_PE10 ISOFORMIN PTV-------------ARPRTS-RLGLASSS--SSESEDSEGPCQPAQKRPRPSASIRQA LOXAF185_PE9 ENSLAFG00000027120 PTV-------------ARPRTS-RLGLASSS--SSESEDSEGPCQPAQKRPRPSASIRQA MACEUGS_6643_PE1 NOISO XXX-------------XXXXXX----XXXXXXSSSEEDDDMVPFQPVKKRPRLST-GHLS MACMU8_150_PE8 ENSMMUG00000002655 PAV-------------ARPRRS-RHGPASSS--SSEGEDSAGPPRVSQKRPR-------- MACMU8_150_PE9 ISOFORMIN PAV-------------ARPRRS-RHGPASSS--SSEGEDSAGPPRVSQKRPR-------- MONDO3_446_PE18 ISOFORMIN LGF-------------SRPQSY----QAGDGASSSEEDVDTVPFQPFKKRPRLLNMEQRA MONDO3_446_PE19 ENSMODG00000010893 LGF-------------SRPQSY----QAGDGASSSEEDVDTVPFQPFKKRPRLLNMEQRA MOUSE15_PE693 NOISO SAV-------------SRPRKT-RHRPTSSSSSSE-DEDNPSPCRPSQKRLRHTT--QQG OCHPRGS_3363_PE1 NOISO PMA-------------ARPRRH-RARMVSNS--SSEDEDDSGRPWPSQKRPRHSA----- ORYLA22_10_PE32 NOISO PISPKRRQNF----GSSLRHRARGAETALLSSSSDDSDCPVSPLRPVRPRHPHPAAPSQN PANTR8_151_PE18 ENSPTRG00000020702 PAM-------------ARPRRS-RHGPASSSS-SSEGEDSAGPARPSQKRPRCSATAQRV PONPY8_158_PE43 NOISO TAV-------------ARPRRS-RHGPASSSS-SSEGEDSTGPPRPSQKRPRCSATAQRV PROCAGS_4222_PE3 NOISO PAV-------------AGPWRG-RLGLASSR--SSDSEDGEGPRQPAQKRXXXXXXXXXX PTEVAGS_3119_PE5 NOISO PPV-------------ARPGRS-RHKLASSS--SSEGEDSTGAPQPTRKRPRRSGPAQQA RAT7_PE1316 NOISO SAV-------------CRPRKN-RHRPASSSSSSEDDDDNTNPCRPSQKRLRHST--QQG TETNG10_PE412 NOISO PASPGRW----RGGGSTRRHRQRGTESAVLPSP--------------------ESLPNTD TURTRGS_2770_PE5 NOISO PAA-------------ARPRRS-RHKLASGG--SSDGEENPGPPRPPQKRPR-------- XENTR8389_PE1 ISOFORMIN -----------------------------------PQRELLTPLKPVKKRPRFEGKRPLA XENTR8389_PE2 ENSXETG00000020475 PICASPRAG----------------GDMG--FSTETFEQLLTPLKPVKKRPRY------- MATCH CONSENSUS ?????????????????????????????????????????????P??KR?R????????

AILMEGL192891_1_1_PE28 NOISO RTGVPGST------SS----------REAVAVSAT----RAAVRGVGGAQICCPGPGLRW ANOCA949_PE5 NOISO TAWSPSAL------LA---------REEGGPITTAPSEYAAAMRGVGSALSRGP----PS BOVIN14_1_PE29 NOISO KAPMPGPA------SD----------REAATTSTSWAAYREAIRGVGSAQTCRLGPSPLR CALJA16_53_PE31 ENSCJAG00000021411 AAQTPGPA------SN----------REEAAASASRATYKAAIRGVGSAQSRL-GPGPLW CALJA16_53_PE32 ISOFORMIN AAQTPGPA------SN----------REEAAASASRATYKAAIRGVGSAQSRL-GPGPLW CANFA13_42_PE31 NOISO AR-RPGSS------SS----------RDTAAEV------------------------GPR CAVPO95_4_PE29 NOISO EAWTSGSA------SS----------KEAATASTSLAAYQAAIRSVGGVQSRCQGPGSFR DANRE17_10_PE1 NOISO PQEVPSSQELPSVYGIKETTVP-------PQSESGRLEYQKAMQNLGSAKSRLFSQSLSE DASNOGS_4799_PE2 NOISO VAPTPGPA------GD----------SKAAA--------------RGSTQSCSPGPSWPP DIPORGS_3810_PE3 NOISO VVRKPGPT------NS----------KEAAAVHAGRATCKAAIRGEGSAQSRCLSSCPPR ERIEUGS_7142_PE4 NOISO KAQKPSPT------GN----------RELAVVGAGRAAYVAAIRGVGSAQNCQLGSSPLW FELCAGS_5236_PE3 NOISO KARTPGST------SN----------REAAAASAP----WVGVRGVGSAQSCHLGSGPPW FUGRU10_1_PE41 ENSTRUG00000007494 ANSA------PSSVRENTREPS-------VASVFAREEYQSAIRSLGSAKTRLQG--PTQ GASACGROUPXV_8_PE3 ISOFORMIN NNAA------PNSGRESLREAP-------GPSVFAREEYHSAIRGVGSAKTLLQG--LSQ GASACGROUPXV_8_PE4 ENSGACG00000009209 NNAA------PNSGRESLREAP-------GPSVFAREEYHSAIRGVGSAKTLLQG--LSQ GORGO8_150_PE69 ENSGGOG00000016222 AAWTPGPA------SN----------REAATASTSRAAYQAAIRGVGSAQSRL-GPGPPR GORGO8_150_PE70 ISOFORMIN AAWTPGPA------SN----------REAATASTSRAAYQAAIRGVGSAQSRL-GPGPPR HORSE9_85_PE50 ENSECAG00000014231 KARIPGPT------SN----------REAATASAGRAAYVAAIRGVGSAQSCRRGPGAPR HORSE9_85_PE51 ISOFORMIN KARIPGPT------SN----------REAATASAGRAAYVAAIRGVGSAQSCRRGPGAPR HS8_PE3560 ENSG00000160949 AAWTPGPA------SN----------REAATASTSRAAYQAAIRGVGSAQSRL-GPGPPR HS8_PE3561 ISOFORMIN AAWTPGPA------SN----------REAATASTSRAAYQAAIRGVGSAQSRL-GPGPPR HS8_PE3562 ISOFORMIN AAWTPGPA------SN----------REAATASTSRAAYQAAIRGVGSAQSRL-GPGPPR LOXAF185_PE10 ISOFORMIN PAQMARFA------GD----------RQAAMASASRAAYQSAVRGVGSAQSRLLGPSQPL LOXAF185_PE9 ENSLAFG00000027120 PAQMARFA------GD----------RQAAMASASRAAYQSAVRGVGSAQSRLLGPSQPL MACEUGS_6643_PE1 NOISO EGATLYSP------ET----------TDSDVASTSRAVYQAAIRGVGSAQARRP------ MACMU8_150_PE8 ENSMMUG00000002655 ------------------------------------------------------------ MACMU8_150_PE9 ISOFORMIN ------------------------------------------------------------ MONDO3_446_PE18 ISOFORMIN EGATLHPT------EN----------IDSDVASASRAVYQAAIRGVGSAQHLFK--AITK MONDO3_446_PE19 ENSMODG00000010893 EGATLHPT------EN----------IDSDVASASRAVYQAAIRGVGSAQHLFK--AITK MOUSE15_PE693 NOISO EVKIPDPP------KS----------RETATSSACRAAYQAAIRGVGSAQSRRLVPSLPR OCHPRGS_3363_PE1 NOISO --------------------------SEAAAAGASRAAYQAAMRGVGSAQSRL-G-SGPR ORYLA22_10_PE32 NOISO NQET------AAVASSARENNP-------APSVFGREEYHSAIRGLGSAKTRLYA--HSQ PANTR8_151_PE18 ENSPTRG00000020702 AAWTPGPA------SN----------REAATASTSRAAYQAAIRGVGSAQSRL-GPGPPR PONPY8_158_PE43 NOISO AARTPGPP------SN----------REAATASTSRAAYQAAIRGVGSAQSRL-GPGPPR PROCAGS_4222_PE3 NOISO XXXXXXXX------XX----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_3119_PE5 NOISO KACMAGHT------SD----------REVAAVGAGRAAYRAAIRGVGSARSCRLESGPSR RAT7_PE1316 NOISO EAKTPDPS------KS----------RETAISSACRAAYQAAIRGVGSAQSRRLVPSLPR TETNG10_PE412 NOISO ANAV------PISGREHAKEPP-------AASVFEREEYQSAIRGLGSAKTRLLA--QPH TURTRGS_2770_PE5 NOISO ---MPSPA------SD----------GEAATASAGWAAYRAAIRSVGSAQRYHLRPSPPR XENTR8389_PE1 ISOFORMIN DSAL-GREHLD---ETEAENPPFPPVHQIRAPDCGMEQYQKAIRDLGSAKSRLLTQSLAQ XENTR8389_PE2 ENSXETG00000020475 -SAL-GREHLD---ETEAENPPFPPVHQIRAPDCGMEQYQKAIRDLGSAKSRLLTQSLAQ MATCH CONSENSUS ??????????????????????????????????????Y??A?R??GSA???????????

AILMEGL192891_1_1_PE28 NOISO ----GPGEPTP-PRAALIPEEACLAGDWLEDDSPLTHSHQGG-YLPH-PQGSGDGTRPGG ANOCA949_PE5 NOISO ----SDRPARPSPAPALIPTEEYIDDDWLDDDLAKRTRRRRRARATPDPRRPWGGS---- BOVIN14_1_PE29 NOISO ----GPSEIPI-PQAALIPQEECLAGDWLEEDFPMSPGHRGR-CPAR-PQSSGDGGRHRA CALJA16_53_PE31 ENSCJAG00000021411 ----GQSKALA-PQAALIPEEECLTGDWLELDTPPVRSRR-P----R-SQSNGDSRRPSS CALJA16_53_PE32 ISOFORMIN ----GQSKALA-PQAALIPEEECLTGDWLELDTPPVRSRR-P----R-SQSNGDSRRPSS CANFA13_42_PE31 NOISO ----GLGEPDP-HRAALIPEEDWLAGDWLEDDSPLTHSHQDG-PVPR-PQGTSRGAPGS- CAVPO95_4_PE29 NOISO ----DTSEGPV-PQAALIPEEEYVARDWLELDEPLMYSRP-S-HLAC-PQDSGDSGSS-- DANRE17_10_PE1 NOISO PAFTSTPAVSANSRAALVPEDQYLADDWLEDDLIDMQPKKKRRV--SEHNATRETT---- DASNOGS_4799_PE2 NOISO ----GTGRTPA-GQAALIPEGEDPAEDWLEDDMPRTHGRRRK-DNCTAP--------GPD DIPORGS_3810_PE3 NOISO ----DSGEAPS-SPAALIPEEEYLSEDWLELDTPLTRSRL-P-RLPR-PQGSWDNRRPSA ERIEUGS_7142_PE4 NOISO ----SPGEAPT-PPAALIPEEEFLTGDWLEEDSLLTHSHWSS-HPAR-PQDSRERNRHSD FELCAGS_5236_PE3 NOISO ----GPGEATL-QRPALIPEEECLASDWLEDDSPLLHSRQDG-HLPR-SPGSGDSTGRSA FUGRU10_1_PE41 ENSTRUG00000007494 PQFSSTPSLSSNNTSALVPEDEYVADDWLEDDLEEIQPKKKRRI--RMDQNEMRGEDLVS GASACGROUPXV_8_PE3 ISOFORMIN PQYSSTAAVPSSNKSALVPEEEYLADDWLEDDLGEIQPKKKRRL--GADQTRSQNRLFNS GASACGROUPXV_8_PE4 ENSGACG00000009209 PQYSSTAAVPSSNKSALVPEEEYLADDWLEDDLGEIQPKKKRRL--GADQIASSSSRSLS GORGO8_150_PE69 ENSGGOG00000016222 ----GHSKALA-PQAALIPEEQCLAGDWLELDMPLTRSRR-P----R-PRGTGDNRRPSS GORGO8_150_PE70 ISOFORMIN ----GHSKALA-PQAALIPEEQCLAGDWLELDMPLTRSRR-P----R-PRGTGDNRRPSS HORSE9_85_PE50 ENSECAG00000014231 ----GAGEAPV-PQAALIPEEECLAGDWLEDDLLLTQSHRGR-RLPR-PQGGGDSTRHCA HORSE9_85_PE51 ISOFORMIN ----GAGEAPV-PQAALIPEEECLAGDWLEDDLLLTQSHRGR-RLPR-PQG--------- HS8_PE3560 ENSG00000160949 ----GHSKALA-PQAALIPEEECLAGDWLELDMPLTRSRR-P----R-PRGTGDNRRPSS HS8_PE3561 ISOFORMIN ----GHSKALA-PQAALIPEEECLAGDWLELDMPLTRSRR-P----R-PRGTGDNRRPSS HS8_PE3562 ISOFORMIN ----GHSKALA-PQAALIPEEECLAGDWLELDMPLTRSRR-P----R-PRGTGDNRRPSS LOXAF185_PE10 ISOFORMIN ----GPGVRPQPPRADLVPEEDCLGEGINPVIPRDARGVV---RPAPTPPRQWGTAPRVQ LOXAF185_PE9 ENSLAFG00000027120 ----GPGVRPQPPRADLVPEEDCLGEGINPVIPRDARGVV---RPAPTPPRQWGTAPRVQ MACEUGS_6643_PE1 NOISO ----DHSKTPM-TQAALIPEEEYLDGDWLEDDMS-LCVHRK--RNHCLPENGSDCTSWSD MACMU8_150_PE8 ENSMMUG00000002655 -------KALA-PQAALIPEEECLAGDWLELDTPLTRSRR-P----R-PQGTGDSRRPSS MACMU8_150_PE9 ISOFORMIN -------KALA-PQAALIPEEECLAGDWLELDTPLTRSRR-P----R-PQGTGDSRRPSS MONDO3_446_PE18 ISOFORMIN ----GPSETSI-AQAALIPEEEYLDGDWLEEDMDSHY-------------SGSDCTSGPD MONDO3_446_PE19 ENSMODG00000010893 ----GPSETSI-AQAALIPEEEYLDGDWLEEDMDSHCVRRK--RSHCFPDSGSDCTSGPD MOUSE15_PE693 NOISO ----GSEEVPA-PKTALIPEEEYLAGEWLEVDTPLTRS-----------------GRPST OCHPRGS_3363_PE1 NOISO ----CLGKVPP-SRAALIPEDEYLAGHWLEMDTPQGHSRQSS-RPPPWAQSSGDSRS--- ORYLA22_10_PE32 NOISO PQLSASAAASSGSRSALVPEDEYVADDWLEDDQFISEPASKGTE--SS------SCDFFS PANTR8_151_PE18 ENSPTRG00000020702 ----GHSKALA-PQAALIPEEECLAGDWLELDMPLTRSRR-P----R-PRGTGDNRRPSS PONPY8_158_PE43 NOISO ----GWSKALA-PQAALIPEKECLAEDWLEQDTPLTRSRR-P----R-PRGTGDNHRRSS PROCAGS_4222_PE3 NOISO ----XXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX-X-XXXXXXXXXXX PTEVAGS_3119_PE5 NOISO ----GPGEAPP-PQAALIPEEECLAGDWLEDDLLVTPGHRGC-RRPQ-PQGCGHSTRHHV RAT7_PE1316 NOISO ----GSNEVPA-PKTALIPEEEFLAEEWLEVDTPLTRSSS-S-------------SRPST TETNG10_PE412 NOISO PQLASTPAVSSSSTSALVPEEEYVADDWLDDDLDAIQPKKKRRV--RLEQNGIRGEDTSS TURTRGS_2770_PE5 NOISO ----GPGEAPS-PRAALLPEEECLAGDWLEEDLPLAHGHGGS-YPPR-PHSSADGSRHSA XENTR8389_PE1 ISOFORMIN PISSTPD---TLSKMALVPSEEYLDDDWLEDDLQETPRSRKRQR--TFTQSIEEEESPVS XENTR8389_PE2 ENSXETG00000020475 PISSTPD---TLSKMALVPSEEYLDDDWLEDDLQETPRSRKRQR--TFTQSIEEEESPVS MATCH CONSENSUS ???????????????AL?PEEE?L??DWLE?D????????????????????????????

AILMEGL192891_1_1_PE28 NOISO LGSGG-SKSPGR--L-RARARQSRLPRLRSWNALSRAGGD-SS----------------- ANOCA949_PE5 NOISO -GGPTRA---G--LP-RERACRLRLCRLPSVFAPLKEIPK-SH----------------- BOVIN14_1_PE29 NOISO SGPGS-DT-ARR--P-RAQARQSRLPYLESWSTPVRADRANSQ----------------- CALJA16_53_PE31 ENSCJAG00000021411 TSES--DSEECR--P-RALAKQVRLTCLQSCSVSVKAG-TNSM----------------- CALJA16_53_PE32 ISOFORMIN TSES--DSEECR--P-RALAKQVRLTCLQSCSVSVKAG-TNSM----------------- CANFA13_42_PE31 NOISO ----G-SRSPGRPRP-RARTRQSRLPHLTSWNAPIGARGEGGA----------------- CAVPO95_4_PE29 NOISO -ASGS-DEHPVR--P-GARARQSRLTCLKSWNPLDKV---GGM----------------- DANRE17_10_PE1 NOISO ----S--RSQNNSS-----TIAEVPPRV-----------QSCSSRGSLSLKKGSNKPRQV DASNOGS_4799_PE2 NOISO SPGGR---------G-ESRRRLSRQTRLQGWSAQVGAGGSSCS----------------- DIPORGS_3810_PE3 NOISO SGSAE-EERPVR--P-QAWSKQSHLACV-----PSKAG-AGSL----------------- ERIEUGS_7142_PE4 NOISO SGSCS-TKNPAR--S-QARAKQSRLTHFQIRRSRAIANRNCSS----------------- FELCAGS_5236_PE3 NOISO SGSGN----KSSSRP-RARARQSRLPRLRSCGALVRAGGDGSS----------------- FUGRU10_1_PE41 ENSTRUG00000007494 SS-AA--RSQNRSIHSDFVPRGTSLS-----------------SRGLSVQKNNSVKPHQV GASACGROUPXV_8_PE3 ISOFORMIN DT-AS--R--S----NYQESL-----------CEKEQLSE----ASPGENDSD------A GASACGROUPXV_8_PE4 ENSGACG00000009209 VK-KN--SSLK----PHQVKM-TQMPGMVSYRRRGHETGN----STPPTNTPA------V GORGO8_150_PE69 ENSGGOG00000016222 TSGS--DSEESR--P-RARAKQVRLTCMQSCSAPVNAG-PSSL----------------- GORGO8_150_PE70 ISOFORMIN TSGS--DSEESR--P-RARAKQVRLTCMQSCSAPVNAG-PSSL----------------- HORSE9_85_PE50 ENSECAG00000014231 LESGR-DKSPVR--L-QAQARQSQLPHLKSRSARVAAGGDHSS----------------- HORSE9_85_PE51 ISOFORMIN ------DKSPVR--L-QAQARQSQLPHLKSRSARVAAGGDHSS----------------- HS8_PE3560 ENSG00000160949 TSGS--DSEESR--P-RARAKQVRLTCMQSCSAPVNAG-PSSL----------------- HS8_PE3561 ISOFORMIN TSGS--DSEESR--P-RARAKQVRLTCMQSCSAPVNAG-PSSL----------------- HS8_PE3562 ISOFORMIN TSGS--DSEESR--P-RARAKQVRLTCMQSCSAPVNAG-PSSL----------------- LOXAF185_PE10 ISOFORMIN TPSGFRVAVSVPPGP-GPEQSHLTPIYHKSWNVEVKASTE-------------------- LOXAF185_PE9 ENSLAFG00000027120 TPSGFRVAVSVPPGP-GPEQSHLTPIYHKSWNVEVKASTE-------------------- MACEUGS_6643_PE1 NOISO SNGGK----PRS--R-EPTH------SNCGQDS---AGQNKGS----------------- MACMU8_150_PE8 ENSMMUG00000002655 TSGS--DSEESR--P-RARAKQVRLTCVQSCSAPVKAG-PSSL----------------- MACMU8_150_PE9 ISOFORMIN TSGS--DSEESR--P-RARAKQVRLTCVQSCSAPVKAG-PSSL----------------- MONDO3_446_PE18 ISOFORMIN SNSGT----CTS--S-KSRSRQSRLTHIVDRTV---LGRTSGS----------------- MONDO3_446_PE19 ENSMODG00000010893 SNSGT----CTS--S-KSRSRQSRLTHIVDRTV---LGRTSGS----------------- MOUSE15_PE693 NOISO SVSDY-ERCPAR--P-RTRVKQSRLTSLDGWCARTQAG-DGSL----------------- OCHPRGS_3363_PE1 NOISO -G-------PGNSTP-LAQTQQSHPASPRR-GGPVDAG-AGSL----------------- ORYLA22_10_PE32 NOISO FY--------R----HDFGMM-SKCPDIYLF-CPAVTTSSSSSSSSSSSRSLS------Q PANTR8_151_PE18 ENSPTRG00000020702 TSGS--DSEESR--P-RARAKQVRLTCMQRCSAPVNAG-PGSL----------------- PONPY8_158_PE43 NOISO TSGS--DSEESR--P-RARAKQVHLTCVQSCSVPVNAG-LSSL----------------- PROCAGS_4222_PE3 NOISO XXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXX-------------------- PTEVAGS_3119_PE5 NOISO SESSS-DESPIR--P-RA--RQSRLPRMSS-SAVGRAAGDCRS----------------- RAT7_PE1316 NOISO SISDY-ERCPAR--P-RTRAKQSRPASLDGWCTRTKAA-DASL----------------- TETNG10_PE412 NOISO SS-AA--RALHRSTNSDIVSRGRSEVTFHVCNCRLHTTGPSSSSRGPSVRKNSSA----- TURTRGS_2770_PE5 NOISO SGSGS-EASAIR--P-RARARKSRLSRLKSWSARVRADGACSS----------------- XENTR8389_PE1 ISOFORMIN SQ-ET--EAPA-----QLSRVREKQ-----------------PMRSLSVSNKRS------ XENTR8389_PE2 ENSXETG00000020475 SQ-ET--EAPA-----QLSRNNAFIPRV----------QESAPTRGLGSAKDSS------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192891_1_1_PE28 NOISO ------------AAELPRSP---------DMSRASGPSGD-SPAAGQPLGP--SLPPPIR ANOCA949_PE5 NOISO ------------PVQPPSAI-------QKIRSCIESPCGG-DSTAGHLQAP--APPPPIR BOVIN14_1_PE29 NOISO ------------ATEPARSP---------DVPRVVAPTGE-NPTTGHLPGQ--VLPPPIR CALJA16_53_PE31 ENSCJAG00000021411 ------------ASESPGSP---------STSRASEPSGD-SSAAGQLVGP--ALPPPIR CALJA16_53_PE32 ISOFORMIN ------------ASESPGSP---------STSRASEPSGD-SSAAGQLVGP--ALPPPIR CANFA13_42_PE31 NOISO ------------AAEPPRSP---------NTSRASGPGGD-SPAAGQPSGP--PVPPPIR CAVPO95_4_PE29 NOISO ------------AAEPSGNP---------IMPRALGPSGE-NSEAGQSMSL--VPPPPIR DANRE17_10_PE1 NOISO KMNQLPGMVMLGRREVSRSQSPIMTQESDHIQEPAPPSHQAMPPASFQ-NRAAHVPAPIR DASNOGS_4799_PE2 NOISO ------------AAAPPESP---------TVPTENPPTGQ-------PPXXXXXXXXXXX DIPORGS_3810_PE3 NOISO ------------ATEPQRIP---------SAPRVLGPSGE-NLAAGQSSVL--IQPPSIR ERIEUGS_7142_PE4 NOISO ------------SKNPPGSP---------NVPRTLERGRE-EPAAAQPMGLLPPPPPPIR FELCAGS_5236_PE3 NOISO ------------AAEPPWSP---------DVSRASGPSGEKSPVAGQPSGP--SLPPPIR FUGRU10_1_PE41 ENSTRUG00000007494 KMTQIPGMVRLGRREPP--------------------------------AVPSCLAPPIR GASACGROUPXV_8_PE3 ISOFORMIN RDGQPP-----AQCVAA--------------------------------SMQRSLPPPIR GASACGROUPXV_8_PE4 ENSGACG00000009209 NLFQPP-----AQCVAA--------------------------------SMQRSLPPPIR GORGO8_150_PE69 ENSGGOG00000016222 ------------ASEPPGSP---------STPRVSEPSGD-ISAAGQPLGP--ALPPPIR GORGO8_150_PE70 ISOFORMIN ------------ASEPPGSP---------STPRVSEPSGD-ISAAGQPLGP--ALPPPIR HORSE9_85_PE50 ENSECAG00000014231 ------------AAEPPQSP---------DVPRASGPSGE-TPVAGQPSGP--VLPPPIR HORSE9_85_PE51 ISOFORMIN ------------AAEPPQSP---------DVPRASGPSGE-TPVAGQPSGP--VLPPPIR HS8_PE3560 ENSG00000160949 ------------ASEPPGSP---------STPRVSEPSGD-SSAAGQPLGP--APPPPIR HS8_PE3561 ISOFORMIN ------------ASEPPGSP---------STPRVSEPSGD-SSAAGQPLGP--APPPPIR HS8_PE3562 ISOFORMIN ------------ASEPPGSP---------STPRVSEPSGD-SSAAGQPLGP--APPPPIR LOXAF185_PE10 ISOFORMIN ------------ANSAAGSP---------VTPEASGPGQE-SLLAGQPSGP--ALLPPIR LOXAF185_PE9 ENSLAFG00000027120 ------------ANSAAGSP---------VTPEASGPGQE-SLLAGQPSGP--ALLPPIR MACEUGS_6643_PE1 NOISO ------------SNLTEENP---------SVSRVSGASGE-SPSAG---CS--AAPPPLR MACMU8_150_PE8 ENSMMUG00000002655 ------------SSEPPGSP---------STARVSEPSGD-SSAAGQPLGL--AMPPPIR MACMU8_150_PE9 ISOFORMIN ------------SSEPPGSP---------STARVSEPSGD-SSAAGQPLGL--AMPPPIR MONDO3_446_PE18 ISOFORMIN ------------SNLTGENT---------SNSRVSGASGE-SPSPGYLPCS--AGPPPIR MONDO3_446_PE19 ENSMODG00000010893 ------------SNLTGENT---------SNSRVSGASGE-SPSPGYLPCS--AGPPPIR MOUSE15_PE693 NOISO ------------NAEPAENP---------SVPRTSGPNKE-NYAAGQPLLL--VQPPPIR OCHPRGS_3363_PE1 NOISO ------------T---------------------ADPAGG-NLPKGQPSGP--VPPPPLR ORYLA22_10_PE32 NOISO RRNGLP-----APSAAA--------------------------------SMPACLPPPIR PANTR8_151_PE18 ENSPTRG00000020702 ------------ASEPPGSP---------STARVSELSGD-SSAAGQPLGP--ALPPPIR PONPY8_158_PE43 NOISO ------------ASEPPGSP---------STARVSEPSGD-SSAAGQPLGP--ALPPPIR PROCAGS_4222_PE3 NOISO ------------XXXXXXXX---------XXXXXXXXXXX-XXXXXXXXGL--ALPPPIR PTEVAGS_3119_PE5 NOISO ------------ATEPPQSP---------GVP-----GGE-RPAEGQPLGP--ALLPPIR RAT7_PE1316 NOISO ------------TAEPTENS---------SMPRTTGPNKE-NCAAGQPLLL--VQPPPIR TETNG10_PE412 NOISO -----------KPQQPP--------------------------------TVPSSLPPPIR TURTRGS_2770_PE5 NOISO ------------AAEPPRSP---------DVPRALEPIGG-SPAAGQPLGQ--ALLPPIR XENTR8389_PE1 ISOFORMIN -----------------RQT----KLTQ-IVDRTVV-------PAG-V-VLNPTVPPPIR XENTR8389_PE2 ENSXETG00000020475 -----------------GLLSPVILQVG-SQGGPTR-------PAG-V-VLNPTVPPPIR MATCH CONSENSUS ???????????????????????????????????????????????????????PPPIR

AILMEGL192891_1_1_PE28 NOISO VRVRVQDSLFLIPVPHSR-ETHSVAWLAEQAAQRYCQACGLLPRLVLRKEGALLAPQDPI ANOCA949_PE5 NOISO VRVRVQDNVFLIPVPHSDREGCLVSWLAEQASQRYYQACGLLPLLTLKKEGALLAPQDRI BOVIN14_1_PE29 NOISO VRVRVQDNLFLIPVPH-R-EAHSVAWLAEQAAQRHYQASGLLPRLSLQKEGALLAPQDPI CALJA16_53_PE31 ENSCJAG00000021411 VRVQVQDHLFLIPVPHSS-ETHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDPI CALJA16_53_PE32 ISOFORMIN VRVQVQDHLFLIPVPHSS-ETHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDPI CANFA13_42_PE31 NOISO VRVRVQDSLFLVPVPHSK-EAHSVAWLAEQAARRYCQACGLLPRLLLRKEGALLAPQDPI CAVPO95_4_PE29 NOISO VRVRVQDHLFLIPVPHSN-EAHSVAWLVEQAAQRYYQTFGLLPRLTLQKEGALLAPQDPI DANRE17_10_PE1 NOISO MRVKVQDNVFLIPVPHSEADSCTVAWLCDQAAQRYYQMCGLLPRLSLQKEGALLLPTDPL DASNOGS_4799_PE2 NOISO XXXXXXXXXXXXXXXXXX--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX DIPORGS_3810_PE3 NOISO VRVRIQDHLFLIPVPHSS-DVHSVAWLADQAAQRYYQTCGLLPRLTLRKEGALLASQDPI ERIEUGS_7142_PE4 NOISO VRVRFQDNLFLIPVPHSS-EARSVGWLAEQAAQRYYQACGLLPHLSLRKEGALLAPQDPI FELCAGS_5236_PE3 NOISO VRVRVQDSLFLIPVPYXX-XXXXXXXXXXXXXXXXXXXXXXLPRLVLRKEGALLAPQDPI FUGRU10_1_PE41 ENSTRUG00000007494 VRVRVQEDVFLIPVPQSEADSCTVSWLCEQASQRYYQKCGLLPRLSLQKEGALLSPQDLL GASACGROUPXV_8_PE3 ISOFORMIN MRVRVQEDVFLIPVPQREADSCTVSWLCEQAAQRYYQKCGLLPRLSLQKEGALLSPQDPL GASACGROUPXV_8_PE4 ENSGACG00000009209 MRVRVQEDVFLIPVPQREADSCTVSWLCEQAAQRYYQKCGLLPRLSLQKEGALLSPQDPL GORGO8_150_PE69 ENSGGOG00000016222 VRVQVQDHLFLIPVPHSS-DTHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLI GORGO8_150_PE70 ISOFORMIN VRVQVQDHLFLIPVPHSS-DTHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLI HORSE9_85_PE50 ENSECAG00000014231 VRVRVQDNLFLIPVPH-R-EAHSVAWLAEQAAQRYYQACGLLPRLTLQKDGALLAPQDPI HORSE9_85_PE51 ISOFORMIN VRVRVQDNLFLIPVPH-R-EAHSVAWLAEQAAQRYYQACGLLPRLTLQKDGALLAPQDPI HS8_PE3560 ENSG00000160949 VRVQVQDHLFLIPVPHSS-DTHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLI HS8_PE3561 ISOFORMIN VRVQVQDHLFLIPVPHSS-DTHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLI HS8_PE3562 ISOFORMIN VRVQVQDHLFLIPVPHSS-DTHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLI LOXAF185_PE10 ISOFORMIN VRVRVQDNLFLIPVPHST-EAHSVAWLAERAAQRYYQTCGLLPRLTLQKEGALLAPQDAI LOXAF185_PE9 ENSLAFG00000027120 VRVRVQDNLFLIPVPHST-EAHSVAWLAERAAQRYYQTCGLLPRLTLQKEGALLAPQDAI MACEUGS_6643_PE1 NOISO VRVRVQDDVFLIPVPQSS-ERHPVSWLADQASQRYYQTCGLLTWLILKKEGALLAPEDLI MACMU8_150_PE8 ENSMMUG00000002655 VRVQVQDHLFLIPVPHSS-ETHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDPI MACMU8_150_PE9 ISOFORMIN VRVQVQDHLFLIPVPHSS-ETHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDPI MONDO3_446_PE18 ISOFORMIN VRVRVQDNIFLIPVPHS--KGHPVSWLAEQASQRYYQTCGLLPRLTLKKEGALLAPEDLI MONDO3_446_PE19 ENSMODG00000010893 VRVRVQDNIFLIPVPHSGSKGHPVSWLAEQASQRYYQTCGLLPRLTLKKEGALLAPEDLI MOUSE15_PE693 NOISO VRVQIQDNLFLIPVPQS--DIRPVAWLTEQAAQRYFQTCGLLPRLTLRKDGALLAPQDPI OCHPRGS_3363_PE1 NOISO VRVRVQDNVFLIPVPHSS-EAPLVAWLAEQAAQRYYQTCGLLPRLTLQKEGALLDPQDPI ORYLA22_10_PE32 NOISO MRVRVQEDVFLIPVPQSEA--VTVWWLCEQAAQRYYQKCGLLPRLSLQKEGALLSPQDPL PANTR8_151_PE18 ENSPTRG00000020702 VRVQVQDHLFLIPVPHSS-DTHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLI PONPY8_158_PE43 NOISO VRVQVQDHLFLIPVPHSS-ETHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLI PROCAGS_4222_PE3 NOISO VRVRVEDSLFLIPVPHNT-EAHSVAWLAEQAAQRYHQTCGLLPQLTLRKEGALLAPQDAI PTEVAGS_3119_PE5 NOISO VRVRVQDSLFLIPVPHSK-EAHSVAWLAEQAAQRYYQACGLLPRLTLRKEGALLAPQDPV RAT7_PE1316 NOISO VRVQIQDNLFLIPVPHS--DVHSVAWLAEQAAQRYFQTCGLLPRLTLRKDGALLAPQDPI TETNG10_PE412 NOISO VRVRVQEDVFLIPVPQSEADSCTVSWLCEQASQRYYHKCGLLPRLSLQKEGALLSPQDLL TURTRGS_2770_PE5 NOISO VRVRVQHNLFLIPVPQSR-ETHSVAWLAEQAAQRYYQASGLLPRLSLQKEGALLAPQDPI XENTR8389_PE1 ISOFORMIN VRVRVQDNIFLIPIPHSDSETREISWLADEAAQRYYQSCGLLPRLTLKKEGALLAPQDLV XENTR8389_PE2 ENSXETG00000020475 VRVRVQDNIFLIPIPHSDSETREISWLADEAAQRYYQSCGLLPRLTLKKEGALLAPQDLV MATCH CONSENSUS VRV?VQD??FLIPVP?S??????V?WL?EQAAQRYYQ?CGLLPRL?L?KEGALLAPQD??

AILMEGL192891_1_1_PE28 NOISO PDVLQSNEEVLAEVTSWDLPPLTDRYRRACQSLEQEEDQEVLQAVDRQGSGPSFSACSLA ANOCA949_PE5 NOISO VDVLQSNEEVLAEVQSWNLPPLVERYRKACRSLAAEEHRLLLRMLERQESGPSFSVAGVS BOVIN14_1_PE29 NOISO PDVLQSNEEVLAEVTSWDLPPLRDRYRRACQTLEQGEHQQVLQAVEHQGSAPTFSACSLA CALJA16_53_PE31 ENSCJAG00000021411 PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQLLQAVELQGLGPSFSACSLA CALJA16_53_PE32 ISOFORMIN PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQLLQAVELQGLGPSFSACSLA CANFA13_42_PE31 NOISO PDVLQSNEEVLAEVTSWDLPPLTDRYRRACQSLEEEEHQQVLQAMGCQGSGPSFSACSLA CAVPO95_4_PE29 NOISO PDVLQSNDEVLAEVTSWDLPPLTDRYHRACQSLGQGEHVQVLRTIERQGSGPSFSICSLA DANRE17_10_PE1 NOISO LAVLHTNEEVLAEVCSWDLPPLPERYRKACQSLGVEENRRVSRVCEVQDSSSCVSVCGLS DASNOGS_4799_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEHQQVLQAMERQASRPSFSACRLA DIPORGS_3810_PE3 NOISO PDVLQSDDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQWVLQAMECQGSSPSFSACSLA ERIEUGS_7142_PE4 NOISO PDVLQSNEEVLAEVTSWNLPPLAERYRRACQSXXXXTHQQVLQAMERQGSGPSFSTCSLA FELCAGS_5236_PE3 NOISO PDVLQSNEEVLAEVTSWDLPPLADRYRRACQSLQQEEHQEVLQAMECQGSGPSFSACSLA FUGRU10_1_PE41 ENSTRUG00000007494 LTVLHTNEEVLAEVCSWDLPPLPERYKKACQSLAVDENKQVTRLCEVHG-SSSVSACGLS GASACGROUPXV_8_PE3 ISOFORMIN LAVLHTNEEVLAEVSSWDLPPLPERYKKACDSLAVGENKRVTRLCEVQDGSSSVSVCGLS GASACGROUPXV_8_PE4 ENSGACG00000009209 LAVLHTNEEVLAEVSSWDLPPLPERYKKACDSLAVGENKRVTRLCEVQDGSSSVSVCGLS GORGO8_150_PE69 ENSGGOG00000016222 PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGLGLSFSACSLA GORGO8_150_PE70 ISOFORMIN PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGLGLSFSACSLA HORSE9_85_PE50 ENSECAG00000014231 PDVLQSNEEVLAEVTSWDLPPLTDRYRRACQSLEQGEHQQVLQAMERHSSGPLFSACSLA HORSE9_85_PE51 ISOFORMIN PDVLQSNEEVLAEVTSWDLPPLTDRYRRACQSLEQGEHQQVLQAMERHSSGPLFSACSLA HS8_PE3560 ENSG00000160949 PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGLGLSFSACSLA HS8_PE3561 ISOFORMIN PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGLGLSFSACSLA HS8_PE3562 ISOFORMIN PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGLGLSFSACSLA LOXAF185_PE10 ISOFORMIN PDVLQSNEEVLAQVTSWDLPPLADRYHRACQSLGQAEHPQVLQAVERQGSGPAFGACSLA LOXAF185_PE9 ENSLAFG00000027120 PDVLQSNEEVLAQVTSWDLPPLADRYHRACQSLGQAEHPQVLQAVERQGSGPAFGACSLA MACEUGS_6643_PE1 NOISO TDVLQSNEEVLAEVVSCDVTPLTDRYRKVCQNLREAENQLVLQALEQQSSGSSFSACSLA MACMU8_150_PE8 ENSMMUG00000002655 PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGSGLSFSACSLA MACMU8_150_PE9 ISOFORMIN PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGSGLSFSACSLA MONDO3_446_PE18 ISOFORMIN TDVLQSNEEVLAEVVSWDLPPLTDRYRKACQSLREAEHQLVLQALEQQGSGPSFSVCSLA MONDO3_446_PE19 ENSMODG00000010893 TDVLQSNEEVLAEVVSWDLPPLTDRYRKACQSLREAEHQLVLQALEQQGSGPSFSVCSLA MOUSE15_PE693 NOISO PDVLQSNDEVLAEVTSWDLPPLKDRYRRACLSLGQGEHQQVLHAMDHQSSSPSFSACSLA OCHPRGS_3363_PE1 NOISO PDVLQSNDEVLAEVSSWDLPPLADRYRRACQSLGQEEHPQVLQAAECQDASPSFSTHCLA ORYLA22_10_PE32 NOISO LSVLQTNEEVLAEVCSWDLPPLPERYKKACQSLSVDENRRVTRLCEAQDGSSSVSLCGLS PANTR8_151_PE18 ENSPTRG00000020702 PDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGLGLSFSACSLA PONPY8_158_PE43 NOISO PDVLQSNDEVLAEVTSWDLP-LTDRY-RACQSLGQGEHQQVLQAVELQGLGLSFSACSLA PROCAGS_4222_PE3 NOISO PDVLQSGEEVLAQVTSWDLPPLADRYHRACQSLGQAEHPQVLQAMELQGSGPTFAACSLA PTEVAGS_3119_PE5 NOISO PDVLQTNEDVLAEVTSWDLPPLTDRYLRACQSLEQEPHQQVLQAVKHQSLGPSFSACSLA RAT7_PE1316 NOISO PDVLQSNDEVMAEVTSWDLPPLKDRYRRACQSLGQGEHQQVLQAMEHQSSSPSFSACSLA TETNG10_PE412 NOISO LAVLHTNEEVLAEVCSWDLPPLPERYKKACQSLAVDENTRVTRLCEVQDRSASVSVCGLC TURTRGS_2770_PE5 NOISO SDVLQSNEEVLAEVTSWDLPPLTDRYRRACQSLEQGAHQHVLQAMEQQGSGPAFSACSLA XENTR8389_PE1 ISOFORMIN LHVLQSNEEVLAEVHSWDLPPLTDRYRKACQSLAVEENHLLVRALERQESSQCLTFSHLS XENTR8389_PE2 ENSXETG00000020475 LHVLQSNEEVLAEVHSWDLPPLTDRYRKACQSLAVEENHLLVRALERQESSQCLTFSHLS MATCH . : : : . :. CONSENSUS ??VLQSN?EVLAEV?SWDLPPL??RY??ACQSL???E???VL?A?E?Q?????FS?C?L?

AILMEGL192891_1_1_PE28 NOISO LHQTQLTPLLRALKLHTALRELHLAGNRLGDGCAAELLAALGTMPSLVLLDLSSNHLGPE ANOCA949_PE5 NOISO LRGPRLTPLLRALKLQASIRQLCLSGTGLGDDSAEELLASISTMPALRQLDLSSN-RGPE BOVIN14_1_PE29 NOISO LRQAQLTPLLRALKLHSALRELRLAGNRLGDGCVAELLATLDTVPGLTLLDLSSNHLGPE CALJA16_53_PE31 ENSCJAG00000021411 LHQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELLGALGTMPSLALLDLSSNHLGPE CALJA16_53_PE32 ISOFORMIN LHQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELLGALGTMPSLALLDLSSNHLGPE CANFA13_42_PE31 NOISO LRQTQLTPLLRALKLHTALRELRLAGNRLADGCAAELLAALGTLPGLVLLDLSSNHLGPE CAVPO95_4_PE29 NOISO LCQTQLVPLLRALKMHTGLRELRLAGNRLGDGCATELLSALATIPSLVLLDLSSNHLSQE DANRE17_10_PE1 NOISO LSPASLNPLLRALKLQASLTELRISANRLNDELLPEMMAAAATMPRLRVLDISANQITGE DASNOGS_4799_PE2 NOISO LRPAQLTPLLRALKLHAELRELRLAENRLGDACAAELLAALATMPGLALLDLSSNHLGPE DIPORGS_3810_PE3 NOISO LRQAQLTPLLRALKLHAVLRELHLAGNRLGDGCVPELLAALGTMPSLAILDLSSNHLGQE ERIEUGS_7142_PE4 NOISO LRQAQLTPLLRALKMHTALRELRLAGNRLGDTCVLELLATLCTMPSLVLLDLSSNHLGPE FELCAGS_5236_PE3 NOISO LRQTQLTPLLRALKLHAALRELHLAGNRLGDGCAAELLAALGTMPGLILLDLSSNHLGPE FUGRU10_1_PE41 ENSTRUG00000007494 LGPSSLRPLLRALKLQSSLTELRLSGNRLDDELLPELVSTTVTMPRLQVLDISACCITAE GASACGROUPXV_8_PE3 ISOFORMIN LAASCLNPLLRALKLQASLTELRISGNRLHDNLVPELVAATITMPRLRLLDISANGITGD GASACGROUPXV_8_PE4 ENSGACG00000009209 LAASCLNPLLRALKLQASLTELRISGNRLHDNLVPELVAATITMPRLRLLDISANGITGD GORGO8_150_PE69 ENSGGOG00000016222 LDQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLALLDLSSNHLGPE GORGO8_150_PE70 ISOFORMIN LDQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLALLDLSSNHLGPE HORSE9_85_PE50 ENSECAG00000014231 LRQAQLTPLLRALKLHTALRELRLAGNRLGDGCATELLAVLGTVPNLTLLDLSSNHLGPE HORSE9_85_PE51 ISOFORMIN LRQAQLTPLLRALKLHTALRELRLAGNRLGDGCATELLAVLGTVPNLTLLDLSSNHLGPE HS8_PE3560 ENSG00000160949 LDQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLALLDLSSNHLGPE HS8_PE3561 ISOFORMIN LDQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLALLDLSSNHLGPE HS8_PE3562 ISOFORMIN LDQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLALLDLSSNHLGPE LOXAF185_PE10 ISOFORMIN LRQAQLTPLLRALKLHTALRELRLAGNRLGDGCAAELLAALGTMPNLALLDLSSNHLGSA LOXAF185_PE9 ENSLAFG00000027120 LRQAQLTPLLRALKLHTALRELRLAGNRLGDGCAAELLAALGTMPNLALLDLSSNHLGSA MACEUGS_6643_PE1 NOISO LRPAQLTPLLRALKLHTSLRELHLVG