Alignment of the gene Family HOG000113104 of HOGENOM

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Threshold: 50% 80% 100%
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Isoforms are ON
AILMEGL193302_1_PE1 NOISO PPRRRPGWAALRL-RR--HLSPPPANAALAAVATTPLLSSGTPTALIGTGSSCPGAMWLX BOVINX_36_PE2 NOISO -----------RARPRCPRPAAVSSRSLLRPSRTSPDTP--------PTPSPCLLGVLVR CANFAX_87_PE3 NOISO --MASCSCARDQATRR-LSAAAAATAAALAVVATTPLLPLGTSTALIGTGSSCPGAMWLS CAVPO46_13_PE3 NOISO --MASCSFALDQATRR-LRAAAAAAAAALAAVATTSLPSLGTSTALIGTGSSCPGAMWLS DIPORGS_1216_PE4 NOISO --MASCSFTRDQATRR-LRAAAAATAAALAAVATTPVLSSGTPTALIGTGSSCPGAMWLS ECHTEGS_1467_PE6 NOISO --MGSCSGREATQSLKI---------------ASTPQ----PPPAILPPPPSSFGELIXX FELCAGS_3812_PE2 NOISO ------------------------------------------------------------ HORSEX_88_PE4 NOISO ------------------------------------------------------------ HSX_PE1979 NOISO --MASCSFTRDQATRR-LRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLS LOXAF32_24_PE1 NOISO --LYSCAFQSRAFVRG---GAGLEEPAARWAAATTSLLSSETPTALIGTG-SCPGAMWLS MACEUSCAFFOLD7292_PE1 NOISO ------------------------------------------------------------ MACMUX_110_PE2 NOISO -------------------------------------------XALIGTGSSCPGAMWLS MICMUGS_492_1_PE8 NOISO --MASCSFARDQATRR-LRGAAAAAAAALTAAATTPLLS-STPTALIGTGSSCPGAMWLS MOUSEX_PE1785 NOISO --MASCSFSGHQALRRLRASAAAAASAALAAVATTPLLSSGTRTALIGTGSSCPGAMWLS MYOLUGS_2407_PE1 NOISO --MASCSFVNDRATRRL-RAAA--ATAAALAVANTPLLSSGNLSALIGTGSSCREAWWLS OCHPR47473_PE1 NOISO ------------------------------------------------------------ OTOGAGS_3120_PE3 NOISO --MASCSFARDQAXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXMWLS PIGX_90_PE1 NOISO --MASCSFARDQATRR-LRAAAAATAAALAAVATTPLLSSGTPTALIGTGSSCPGAMWLS PONPYX_109_PE1 NOISO --MASCSFTRDQATRR-LRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLS PROCAGS_1337_PE5 NOISO --MASCAFTCGQATSSL-RAAVTAAAAAPPAAAATPLLSSETPTALIGTGSSCPGAMWLS PTEVAGS_657_PE5 NOISO --MASCSFARGQATRR-LRATAAATAAALAAVATTPLLSSGTPTALIGTGSSCPGAMWLS RABITX_59_PE3 NOISO ------------------------------------------------------------ RATX_PE348 ENSRNOG00000019011 ------------------------------------------------------------ RATX_PE349 ISOFORMIN ------------------------------------------------------------ TUPGBGS_903_PE4 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193302_1_PE1 NOISO E--------------------SDEEDLPVGDEVCKRGYLRKQKHGHWRYFVLKL------ BOVINX_36_PE2 NOISO TSVAKGPASSRRSSRDPQEPQRPPREAAVTDEVCKRGYLRKQKHGHWRYFVLKLETADAP CANFAX_87_PE3 NOISO T------ATGSRS-----DSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAP CAVPO46_13_PE3 NOISO N------AAGSRS-----DSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETTDAP DIPORGS_1216_PE4 NOISO P------ATGSRS-----DSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAP ECHTEGS_1467_PE6 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX FELCAGS_3812_PE2 NOISO --------------------------LPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAP HORSEX_88_PE4 NOISO ------------------------------------------------------------ HSX_PE1979 NOISO T------ATGSRS-----DSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAP LOXAF32_24_PE1 NOISO A------ATGSRS-----DSESEEEDLPVGTKFCKRGYLRKQKHGHRRYFVLKLEA-ERP MACEUSCAFFOLD7292_PE1 NOISO ------------------------------------------------------------ MACMUX_110_PE2 NOISO T------ATGSRS-----DSESDEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAP MICMUGS_492_1_PE8 NOISO T------ATGSRS-----DSESEEED-PVGAEVCKRGYLRKQKHGHRRFFVLKLETA-AP MOUSEX_PE1785 NOISO T------ATGSRS-----DSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAP MYOLUGS_2407_PE1 NOISO SATGPGP-----------HSESGEEDFSVGQEICKRGYLRQKNLEHKCYFVFXXXXXXXX OCHPR47473_PE1 NOISO ------------------------------------------------------------ OTOGAGS_3120_PE3 NOISO P------ATGSRS-----DSESEEEDLPVGAEVCKRGYLRKQKHGHRRYFVLKLETADAP PIGX_90_PE1 NOISO T------ATGSRS-----DSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAP PONPYX_109_PE1 NOISO T------ATGSRS-----DSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAP PROCAGS_1337_PE5 NOISO T------ATGSRS-----DSESDEDDLPIGDEVCKRGYLRKQKHGHRRYFVLKLETADAP PTEVAGS_657_PE5 NOISO T------ATGSRS-----DSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAP RABITX_59_PE3 NOISO -----------------------------------------------------LETADAP RATX_PE348 ENSRNOG00000019011 ------------------------------DEVCKRGYLRKQKHGQRRYFVLKLETEDAP RATX_PE349 ISOFORMIN ------------------------------DEVCKRGYLRKQKHGQRRYFVLKLETEDAP TUPGBGS_903_PE4 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193302_1_PE1 NOISO -------------------------------------PRRVITLYQCFSVSQRADARYRH BOVINX_36_PE2 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGATVPALIAPRRVITLYQCFSVSQRADARYPH CANFAX_87_PE3 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADARYRH CAVPO46_13_PE3 NOISO ARL-YYENARKFRHSVRAAAAAAAAAASGTAVPALIPPRRVIILYQCFSVSQRADARYRH DIPORGS_1216_PE4 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAVPSLIPPRRVITLYQCFSVSQRADARYRH ECHTEGS_1467_PE6 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX FELCAGS_3812_PE2 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGATVPALIPPRRVITLYQCFSVSQRADARYRH HORSEX_88_PE4 NOISO ------------------------------------------------------------ HSX_PE1979 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRH LOXAF32_24_PE1 NOISO ARLEYYENARKFRHSVRAAAAA-AAAASGAAVPALIPPRRVITLYQCFSVSQRADARYRH MACEUSCAFFOLD7292_PE1 NOISO -----------FRSSLRAAAAAAAAAAAAAAAPPRAPPRRVIPLYQCFTVSRRADAKHRH MACMUX_110_PE2 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAIPRLIPPRRVIILYQCFSVSQRADARYRH MICMUGS_492_1_PE8 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAVPAQIRPRRVITLYQCFSVSQRADARYRY MOUSEX_PE1785 NOISO ARLEYYRNARKFRHSVRAAAAAAEAAASGAAVPALIPPRRVIILYQCFSVSQRADARYRH MYOLUGS_2407_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX OCHPR47473_PE1 NOISO ------------------------------------------------------------ OTOGAGS_3120_PE3 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAFPALIPPRRVITLYQCFSVSQRADARYRH PIGX_90_PE1 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADAKYRH PONPYX_109_PE1 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGSAIPPLIPPRRVITLYQCFSVSQRADARYRH PROCAGS_1337_PE5 NOISO ARLEYYENARKFRHSVRAAAAAAEAAASGAAVPALIPPRRVITLYQCFSVSQRADARYKH PTEVAGS_657_PE5 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAIPALIPPRRVITLYQCFSVSQRADARYPH RABITX_59_PE3 NOISO ARLEYYENARKFRHSVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADARYRH RATX_PE348 ENSRNOG00000019011 ARLEYYQNARKFRLSVRAAA----------------APRRVIILYQCFSVSQRADARYRH RATX_PE349 ISOFORMIN ARLEYYQNARKFRLSVRAAA----------------APRRVIILYQCFSVSQRADARYRH TUPGBGS_903_PE4 NOISO ------------------------------------------------------------ MATCH CONSENSUS ?????????????????????????????????????PRRVI?LYQCF?VS?RADA????

AILMEGL193302_1_PE1 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRC-------------------- BOVINX_36_PE2 NOISO LIALFTQNEYFAMVAENESEQESWYLLLSRLILESKRRRCGRLGAQPEGEPAALAA-AAA CANFAX_87_PE3 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTPGAQPDGEPTALAA-AAA CAVPO46_13_PE3 NOISO LIALFTQNEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGALSEGEPA-------- DIPORGS_1216_PE4 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLSAQPDGEPAPLAA-VAA ECHTEGS_1467_PE6 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRRRCSPPE--------SAEAAAAA FELCAGS_3812_PE2 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTPGAQPDGEPAALAA-AAA HORSEX_88_PE4 NOISO ------------------------YLLLSRLILESKR-RCGT-GAQPDGEPAALAA-AAA HSX_PE1979 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAA-AAA LOXAF32_24_PE1 NOISO LIALFTQDEYFAMVAENESEQESWCVLLSRLILQSKRRRCGTPGAEPDQEGSALAVAAAA MACEUSCAFFOLD7292_PE1 NOISO LIALYTKDDYFAMVAESEQEQESWYQALSLLMGQSKTRSYGTSGARPDEGVRSA----AA MACMUX_110_PE2 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLRAQPDGEPAALAA-AAA MICMUGS_492_1_PE8 NOISO LIALFTQDEYFAMVAENESKQESWYLLLSRLILESKRRRCGTLGAHPEGKPAALAA-PAA MOUSEX_PE1785 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGALPDGEPAALAA-AAA MYOLUGS_2407_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XAV OCHPR47473_PE1 NOISO ------------------------------------------------------------ OTOGAGS_3120_PE3 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLSAQPDGEPAALAA-AAA PIGX_90_PE1 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTPGAQPDGEPAALAA-AAA PONPYX_109_PE1 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAA-AAA PROCAGS_1337_PE5 NOISO LIALFTQDEYFAMVAENESEQESWYVLLSRLILESKRRRCRTPGAQPDQEGAALGAVAAA PTEVAGS_657_PE5 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRXXXXXXXXXXXXXXXXX-XAA RABITX_59_PE3 NOISO LIALFTQDEYFAMVAENESEQESWYLLLSRLILDSKRRRCGTLGALADREPAARAA-AAA RATX_PE348 ENSRNOG00000019011 LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAA-AAA RATX_PE349 ISOFORMIN LIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAA-AAA TUPGBGS_903_PE4 NOISO ------------------------------------------------------------ MATCH CONSENSUS LIAL?T???YFAMVAE?E??QESWY?LLSRLIL?SKRRRC??????????????????AA

AILMEGL193302_1_PE1 NOISO -EPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC BOVINX_36_PE2 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVLFVRLNTEVASVVVQLLSIRRC CANFAX_87_PE3 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVLFVRLNTEVASVVVQLLSIRRC CAVPO46_13_PE3 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC DIPORGS_1216_PE4 NOISO AEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTDVASVVVQLLSIRRC ECHTEGS_1467_PE6 NOISO VEPSFYKDV-QVVVKPRELHR--KESSVFRLCLTDEEVVLVRLNTEVASLVVQLLSIRRC FELCAGS_3812_PE2 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC HORSEX_88_PE4 NOISO AEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC HSX_PE1979 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC LOXAF32_24_PE1 NOISO AEPPFYKDVWQVVIKPKGLGHRKELSGVFRLCLTDEEVLFVRLNTEVASVVVQLLSIRRC MACEUSCAFFOLD7292_PE1 NOISO VPDPPFKEVWQVQVKPKGLGQSKNLSGIYRLCLSSKEVHLVRLNAEVPTVQLQLLSIRRC MACMUX_110_PE2 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC MICMUGS_492_1_PE8 NOISO AEPPFYKKGXQVIVK-RGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC MOUSEX_PE1785 NOISO AEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC MYOLUGS_2407_PE1 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEE-VFVRLNTEVASVVVQLLSIRRC OCHPR47473_PE1 NOISO ------------------------------------------------------------ OTOGAGS_3120_PE3 NOISO VEPPFYKDVWQVIVKPRGLGHKKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC PIGX_90_PE1 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC PONPYX_109_PE1 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC PROCAGS_1337_PE5 NOISO SEPPFYKDVWQVVIKPRGLGHRKELSGVFRLCLTDEEVLFVRLNTEVASVVVQLLSIRRC PTEVAGS_657_PE5 NOISO AEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC RABITX_59_PE3 NOISO AEPPFYRDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC RATX_PE348 ENSRNOG00000019011 AEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC RATX_PE349 ISOFORMIN AEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC TUPGBGS_903_PE4 NOISO ------------------------------------------------------------ MATCH CONSENSUS ?EPPFYKDVWQV?VKPRGLGHRKELSGVFRLCLTDEEV?FVRLNTEVASVVVQLLSIRRC

AILMEGL193302_1_PE1 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS BOVINX_36_PE2 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS CANFAX_87_PE3 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS CAVPO46_13_PE3 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS DIPORGS_1216_PE4 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS ECHTEGS_1467_PE6 NOISO GHSDQYFFLEVGRSSVIGPGELWMQVDDCVVAQQMHELFLEKMRALCAD-EYLARCCSYS FELCAGS_3812_PE2 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS HORSEX_88_PE4 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS HSX_PE1979 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS LOXAF32_24_PE1 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS MACEUSCAFFOLD7292_PE1 NOISO GHSEHFFFLEVGRSSSIGPGEIWMQVDDSVVAQHMHETFLETMKALKAFADFRPRSKSQ- MACMUX_110_PE2 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS MICMUGS_492_1_PE8 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS MOUSEX_PE1785 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDSVVAQNMHELFLEKMRALCAD-EYRARCRSYS MYOLUGS_2407_PE1 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMKALCAD-EYRARCRSYS OCHPR47473_PE1 NOISO ------------------------------------------------------------ OTOGAGS_3120_PE3 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRTRCRSYS PIGX_90_PE1 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS PONPYX_109_PE1 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCAD-EYRARCRSYS PROCAGS_1337_PE5 NOISO GHSEQYFFLEVGRSTVIGPGEXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX PTEVAGS_657_PE5 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDSVVAQNMHELFLEKMRALCAD-EYRARCRSYS RABITX_59_PE3 NOISO GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALSAD-DYRARCRSYS RATX_PE348 ENSRNOG00000019011 GHSEQYFFLEVGRSTVIGPGELWMQVDDSVVAQNMHELFLEKMRALCAD-EYRARCRSYS RATX_PE349 ISOFORMIN GHSEQYFFLEVGRSTVIGPGELWMQVDDSVVAQNMHELFLEKMRALCAD-EYRARCRSYS TUPGBGS_903_PE4 NOISO ------------------------------------------------------------ MATCH CONSENSUS GHSEQYFFLEVGRSTVIGPGELWMQVDD?VVAQNMHELFLEKMRALCAD?EYRARCRSYS

AILMEGL193302_1_PE1 NOISO ISIGAHLLTLLSTRRHLDTLPREPGGWLRRSRFDQFYHLRAVGDGEDETLLTRRHITPSE BOVINX_36_PE2 NOISO ISIGGHLLTLLSTRRHLDMLPLEPGGWFRRSRFEQFCHLRAIGDGEDEMLLAGRYITPSE CANFAX_87_PE3 NOISO ISIGAHLLTLLSTRRHLDTLPREPGGWLRRSRFEQFCHLRAIGDGEDEMLLARRYMTPSE CAVPO46_13_PE3 NOISO INIGAHLLTLLSTRRHLGLLPLEPGGWLRRSRFEQFCHIRAISDGEEELLFTRRFITPSE DIPORGS_1216_PE4 NOISO ISIGAHLLTLLSARRHLGMLPLEPGGWLRKSRF-QFYHLRAIGDGEEERLFTRRLITPSE ECHTEGS_1467_PE6 NOISO IRFGAHLLTLLSARRHLNLPCFPPGGWFRKPRIE-FYSPRASDEIKVKIVITRRFVSASE FELCAGS_3812_PE2 NOISO ISIGAHLLTLLSARRHLDTLPLEPSGWLRRSRFEQFCHLRAIGDGEDEMLLNRRYITPSE HORSEX_88_PE4 NOISO ISIGAHLLTLLSARRHLDVLPLEPSGWLRRSRFEQFCHLRAIGDGEDEMLLTRRYITPSE HSX_PE1979 NOISO ISIGAHLLTLLSARRHLGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSE LOXAF32_24_PE1 NOISO --IGTHLLTLLSARRHLDSLPFQPGGWLRRSRFE-LCHLSAIGDGEDEMFLTRRFISARE MACEUSCAFFOLD7292_PE1 NOISO ---SSCTNHLLSTRRHLGYLQPCLG-MSRRS-RTQYGQLRTSSEGEGTMDRP--FRTVRK MACMUX_110_PE2 NOISO ISIGAHLLTLLSARRHLGLLPLEPGGWLRRSRFEQCCHLRAIGDGEDEMLFTRRFLTPSE MICMUGS_492_1_PE8 NOISO ISIGAHLLTLLSTRRHLGLLPIEPGGWFRRSRFEQFYHFRALGDGEDEMLFSRHLVTREE MOUSEX_PE1785 NOISO ISIGAHLLTLLSTRRHLGLLPLEPGGWLRRYGLEQFCRLRAIRER-EEMLFTRRFISPRE MYOLUGS_2407_PE1 NOISO ISIGAHLLTLLSTRRHLDMVPPEPGGWLRRSRFEQFCHLRAIGDGKNEMLLTRHSVTPSE OCHPR47473_PE1 NOISO -----------------------------------------------EMLVTRRYVT-SE OTOGAGS_3120_PE3 NOISO INIGAHLLTLLARRLG---LLLEPGGWLRRSRFDQF-RLRALGEGEDEMLFTRRFGAPSE PIGX_90_PE1 NOISO ISIGAHLLTLLSARRHLDMLPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLLARRYITPSE PONPYX_109_PE1 NOISO ISIGAHLLTLLSARRHLGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEVLFTRRFITPSE PROCAGS_1337_PE5 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_657_PE5 NOISO ISIGAHLLTLLSTRRHLETLPLEPGGWLRRSRFEQFCHLRTIGDGEDEMLLTRRYVTPNE RABITX_59_PE3 NOISO ISIGAHLLTLLSARRHLGLLPLEPGGWLRRSRTEQFCHLRAIGDGEDEMLVTRRFVTPSE RATX_PE348 ENSRNOG00000019011 ISVGAHLLTLLSTRRHLGSLPLEPGGWFRRSRFEQFCHLRAICHR-EDMLFTRRFIAPRE RATX_PE349 ISOFORMIN ISVGAHLLTLLSTRRHLGSLPLEPGGWFRRSRFEQFCHLRAICHR-EDMLFTRRFIAPRE TUPGBGS_903_PE4 NOISO ------------------------------------------------------------ MATCH CONSENSUS I??G?HLLTLLS?RRHL??????PGGW?RRSR??Q????RA????????L??RR?????E

AILMEGL193302_1_PE1 NOISO PVPHSRRGRLHLPRARRTRRAISVPASCFRRLPPSPVRIPHPAEVPSDRACLSPEAS--- BOVINX_36_PE2 NOISO PVPRSRRGRLHLPRGRRSRRATSVPASFFRHAAPSPVRIR-------------------- CANFAX_87_PE3 NOISO PVLPSRRGRLHLPRARRSRRAISVPASLCRRLPPSPVRVPHPAEVPNDRACLSPEAS--- CAVPO46_13_PE3 NOISO PVPPSRSGRLHLPRPCRSGRSISVPANFLHRLAPSPVCAPHPEESPKDGASA---ASG-- DIPORGS_1216_PE4 NOISO PEPPSTRGRQHLPRARRSRRAISVPASFFRRLEPSPVRDPHPDETPGDEAG-----EA-- ECHTEGS_1467_PE6 NOISO PLLRVRKGRAHLPQLRQDRRAMSVPANCFRHLVSGPRLVPAA--AP----------NGGA FELCAGS_3812_PE2 NOISO PVPTSRRGRLHLPRARRSRRAISVPASFFRP-TPSPVRVPHPVEAPSHRACLSSEAS--- HORSEX_88_PE4 NOISO PVHPSRRGRLYVPRARRSRRAVSVPASCFRHLAPNPVRAPRPAEAPNLGTCLSPEASG-- HSX_PE1979 NOISO PVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSG-- LOXAF32_24_PE1 NOISO PVPHFRRGRQHLPRMRRPRRAMSVPASCFRHLPRKLM--VVPAEAPNDGACLSSEAS--- MACEUSCAFFOLD7292_PE1 NOISO PDA--NPGRMNMAR---------------------------------------------- MACMUX_110_PE2 NOISO PVPHSRRGRLHLPRGRRSRRAS-------------------------------------- MICMUGS_492_1_PE8 NOISO PVIPSRRGRPHLPRMRRSRRAISIPGDLFHRLSSSTVRAPITAEAPNDGAGQSSEAS--- MOUSEX_PE1785 NOISO PPPPFRRGRGHLPRARRSRRAASVPPSLFRRSAPSPGRIPQPEDVPNDRAREASG----- MYOLUGS_2407_PE1 NOISO PVPHSRRGRLHLPRARRSRRTISVPASFFRRLAPCPVRARQTTEPPSDRVCLFSEASS-- OCHPR47473_PE1 NOISO PVSPGRRGRLQLSRARRFRRALSVSPSLFRRLPSSPVRAPQREEAPSDRASLSAEASG-- OTOGAGS_3120_PE3 NOISO PLPPSRQGRLHLPRERRSRRAVSVPASIFRRLTPSPVRAPQPEEARNDRACLSPEAA--- PIGX_90_PE1 NOISO PLPPSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPVRVPQPAEAPSEGACLPSKASG-- PONPYX_109_PE1 NOISO PVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSG-- PROCAGS_1337_PE5 NOISO XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_657_PE5 NOISO PVPRSRRGRLHLPRMRRSRRAVSVPASFFRRLAPSPVLDPHPAEAPSGRACLSLETSG-- RABITX_59_PE3 NOISO PVPPCRRGRLYLPRARRSRRAISMPARFFRRLPASQVRAPHREAAASDRACLSAEAAGSG RATX_PE348 ENSRNOG00000019011 PPPPFKRGRGHLPRARRSRRAVSVPPSFPRRSAPSPGRIRQPEDARNHRACQASG----- RATX_PE349 ISOFORMIN PPPPFKRGRGHLPRARRSRRAVSVPPSFPRRSAPSPGRIRQPEDARNHRACQASG----- TUPGBGS_903_PE4 NOISO ----------------------------------------------SDRAWLSSEASV-- MATCH CONSENSUS P??????GR??LPR?RR?RRA?S?P???????????????????????????????????

AILMEGL193302_1_PE1 NOISO -GSGNSGEEGSPQGQEGQEGN-GGDYMPMNGWGSGNGQGSGGGQGSSGQGSSSQGSGGNQ BOVINX_36_PE2 NOISO ----------------------------------------------------SQSSGGSQ CANFAX_87_PE3 NOISO -GSGNSGDEGSPQGQEGQEGN-GGDYMPMNNWGSGNGRGSGGGQGASGQGSSSQSSGGNQ CAVPO46_13_PE3 NOISO SGPGNSRAKG-KEGKESQEGT-EGDYMPMNNWGSGNGRGSGGDQGTSGQGSSSQSSGGNQ DIPORGS_1216_PE4 NOISO SGSGNSGGKNKPRGKDKEKGS-EGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSQSSGGNQ ECHTEGS_1467_PE6 NOISO SGAGKSGEEGNPQGSDSHEGNDGGDYMPMNNWGSGNGQGSGGGQGSTGQGSSSQGSGGSQ FELCAGS_3812_PE2 NOISO -RPGNSGEEDSPQGKEDQEGT-EGDYMPMNNWGSGNGQGSGGGQGSSGQGSSSQSSGGSQ HORSEX_88_PE4 NOISO SGSGNSGEEGNPEGKEGQEGN-GGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSQGSDGNQ HSX_PE1979 NOISO SGSGNFGEEGNPQGKEDQEGS-GGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQ LOXAF32_24_PE1 NOISO -GSGNSGEEGNPQGNESQEGN-GGDYMPMNNWGSGNGRGTGGGQGSSGQGSSSQSSGGNQ MACEUSCAFFOLD7292_PE1 NOISO -----------PEG---------------------------------------------- MACMUX_110_PE2 NOISO --------------------------------------------------SSSHSSGGNQ MICMUGS_492_1_PE8 NOISO -GSGNSGEEGNPQGREDQEGS-GGDYMPMNNWGNGNGRGSGGGQGSSGQGSSSQSSGGNQ MOUSEX_PE1785 NOISO SSSGNTE----EKDKEGEEGN-RGDCIPMNNWGSGNGRGSGGGRGSSGQGSSSQGSGGRQ MYOLUGS_2407_PE1 NOISO SGSGNSGEEGNPQGQAGQEGN-TGDYMPMNNWGSG------GGQGSSGQGSSSQSSGGNQ OCHPR47473_PE1 NOISO AGTGNPAEEDGSPSREGQEDS-GDDYMPMHSWGSGNGRDSGGGYGSSGQGASSQSSGAGQ OTOGAGS_3120_PE3 NOISO -GSGNSGEEENPQGKENQEES-GGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSQSSGGNQ PIGX_90_PE1 NOISO SGSGNSGEEENPQGKEGQEEN-GGDYMPMNKWGSGNGRGSGGGQGSSGQGPSSQSSGGNQ PONPYX_109_PE1 NOISO SGSGNSGEEGNPQGKEDQEGS-GGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSHSSGGNQ PROCAGS_1337_PE5 NOISO XXXXXXGEEGNPQGNESQEGN-GGDYMPMNNWGSGKGRGSGGGQGSSGPGSSSQGSGGNQ PTEVAGS_657_PE5 NOISO SVSGNRXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSQSSGGNQ RABITX_59_PE3 NOISO SGSGNSAEEGNPQSKEGQEGS-GDDYMPMNSRGSGNGRGSGGGHGSSGQGSSSRTSGGNQ RATX_PE348 ENSRNOG00000019011 SSSGNSE----EKDKE-------------------------------------------- RATX_PE349 ISOFORMIN SSSGNSE----EKDKE-------------------------------------------- TUPGBGS_903_PE4 NOISO SDSDKSEKKDNPQGKDSQEGS-EGDYMPMNNWGAGNGRGSGGGQGSNGQGSSNQSSGGNQ MATCH CONSENSUS ???G???????????????????????????????????????????????SS??SGG?Q

AILMEGL193302_1_PE1 NOISO CSGGGQGGSG----------------GQGAGGNQRSGDGQGTAGGHGSGSG--QGSAGGS BOVINX_36_PE2 NOISO CSGRGHGSGGGQGSSSSHGSSGSGSGDQSAGGNQCSGDGQGTA-GHGSGSG--QGA---G CANFAX_87_PE3 NOISO CSGGGQGSGGGQDSSGGQGSG-----GQGMGGNQRSGAGQGTAGGHGSGGG--QGA---G CAVPO46_13_PE3 NOISO YSSGRQGSGGGQGSSG----------------N--------------------------- DIPORGS_1216_PE4 NOISO CAGGRQGSGGG------HGSS-----GHGSGGNQCSGEGQGTAGGQGSGGS--QGS---G ECHTEGS_1467_PE6 NOISO CSGGGHGSSG----------------GQGAGGNQCSGNGQGTSGGHGSGSG--QGA---G FELCAGS_3812_PE2 NOISO CSGGGQGSGHGQGSSGG----------QGSGGNQRSGDGQGTAGGHGSGSG--QGA---S HORSEX_88_PE4 NOISO CSGGGQGSGGG----------------QGAGGNQCSGDGQGTTGGHGSA----------G HSX_PE1979 NOISO CSGEGQGSRGG------QGSN-----GQGSGGNQCSRDGQGTAGGHGSGGG--QRP---G LOXAF32_24_PE1 NOISO CSGGGQGSGGG---------------GQGAGGNQCSGNGQGTAGGHGSGSG--QGA---G MACEUSCAFFOLD7292_PE1 NOISO ------------------------------------------------------------ MACMUX_110_PE2 NOISO CSGEGQGSRSGQGSSGGQGSN-----GQGSGGNQCSGDGHSTAGGQGSGGG--QRP---G MICMUGS_492_1_PE8 NOISO CSGGGQGSRGG------QGSS-----GQGAGGNQCSGNGQGTAGGS--GGG--QGA---G MOUSEX_PE1785 NOISO GSGGGQGS-----------------GGQGAGGNQCSGNGQGTAGGHGSG----------G MYOLUGS_2407_PE1 NOISO CSGRGQGSGGGQG-----------SGGQGAGGNQCSGNGQSPAGGHGSSSS--QGA---S OCHPR47473_PE1 NOISO CSGGRQGSGGGQGTS-----------GQGAGGNQCSRDGQGSAGGHAAGGGGSSGGQGSG OTOGAGS_3120_PE3 NOISO CSGGGQGSSGGQGSSG----------NQGSGGNQCSGDGQGAAGGHGSGGG--QGA---G PIGX_90_PE1 NOISO CSGRGHGSGG------GQGSG-----GQGAGGNQCSGDGQGTTGGHGSGSG--QGA---G PONPYX_109_PE1 NOISO CAGEGQGSRGGQGSSGGQGSN-----GQGSGGNQCSGDGQGTAGGHGSGGG--QRP---G PROCAGS_1337_PE5 NOISO CSGGGQGSGGGQSSSG----------GQGAGGNQCSGNGQGTSGGHGSGSG--QGA---G PTEVAGS_657_PE5 NOISO CSGAGQSSGGS------QGSS-----GQGSGGSQYSGDGQGTTGGHDSGSG--QGA---G RABITX_59_PE3 NOISO CSGGEQGSGGGQGSSRRQGSG----GGQGSGGNQCSRDGRGTTGGHGSGGG--PGP---G RATX_PE348 ENSRNOG00000019011 ------------------------------------GNGQGTAGGHGSG----------G RATX_PE349 ISOFORMIN ------------------------------------GNGQGTAGGHGSG----------G TUPGBGS_903_PE4 NOISO YSGGRQGSGGGQG-----------SGGQGSGGNQCSGDGQGTAGGHGSGAG--QGA---G MATCH CONSENSUS ?SG???GS???????????????????QG?GGNQ?SG?GQGT?GGHGSG??????????G

AILMEGL193302_1_PE1 NOISO GGHGSGGGRGPGDGHGSGG-GKNSGGAKGSGSGKT-SDGNG--ERGKSLKKRSYFGKLTQ BOVINX_36_PE2 NOISO GGHGSGRDQGAGDGHGSGG-GKNSGGGKGSGSGKG-PEGNG--DRGKSLKKRSYFGKLTQ CANFAX_87_PE3 NOISO GGHGSGDGQGPGDGHGSRR-GKNSGGGKGSGGGKT-SDGSG--DRGKSLKKRSYFGKLTQ CAVPO46_13_PE3 NOISO --------QTPGDGH-----GTNSGGNKGSGSGKS-TEGDG--DHGKSLKKRFYFGKLTQ DIPORGS_1216_PE4 NOISO GGHGSGGGQGPRDGHGSGS-GKNSGGGKGSGNGKG-SDGDD--DRGKSLKKRSYFGKLTQ ECHTEGS_1467_PE6 NOISO GGHGAGGGQGPGGGHGSGG-GKDSGGGEGSGSGKG-SDGNE--ERGKSLKKRSYFGKFTQ FELCAGS_3812_PE2 NOISO GGHGSGSGQGSGDGHGSGG-GKNSGGGKGPGGGKT-PEGSG--ERGKSLKKRSYFGKLTQ HORSEX_88_PE4 NOISO GGHGSGSGQGPGDGHGSGG-GKNSGGGKGSGSGKG-SDGNG--ERGKSLKKRSYFGKLTQ HSX_PE1979 NOISO GGHGSGGGQGPGDGHGSGG-GKNSGGGKGSGSGKG-SDGDG--ERGKSLKKRSYFGKLTQ LOXAF32_24_PE1 NOISO GGHGSGGGQGPGGGHGSGGGGKDSGGGKGSRSGKG-SDGND--ERGKSLKKRSYFSKLTQ MACEUSCAFFOLD7292_PE1 NOISO -------------GRA----RKES------ASGD-------HMEAEKYFKKKTFSSSFST MACMUX_110_PE2 NOISO GGHG------------SGG-GKNSGGGKGSGSGKG-SDADG--ERGKSLKKRSYFGKLTQ MICMUGS_492_1_PE8 NOISO GGRGSGSGRGPGDGHGSGS-GKNSGRGKGSGSGKG-AEGDG--ERGKSLKKRSYFGKLTQ MOUSEX_PE1785 NOISO GGHGSGGGQRPGDGHGSGG-GKNS------GSGKN-SDD---GDRGKSVKKRSYFGKFTQ MYOLUGS_2407_PE1 NOISO GGHGSGSGQGPGDGHNSGG-GKNSGGGKGSGSGKD-SDGNG--EWAKSLKKRSYFGKLIQ OCHPR47473_PE1 NOISO GGHGSGGGQGPGDGRGSGS-GKDSGRGKGSGSGKG-SNGDGDRDRGKSLKKRSYFGKLSQ OTOGAGS_3120_PE3 NOISO GGHGSGRGQGPGDGRGSGS-GKKSGRGKGSGSG-------------KSLKKRSYFGKFSQ PIGX_90_PE1 NOISO GGHGSGRGQGPGDGHGSGG-GKNSGGGRGSGSGKG-SDGTG--ERGKSLKKKSYFGKLTQ PONPYX_109_PE1 NOISO GGHGSGGGQGPGDGHGSGG-GKNSGGGKGSGSGKG-SDGDG--ERGKSLKKRSYFGKLTQ PROCAGS_1337_PE5 NOISO GGHGSGGGQGPGDGHGSGGGGKDSGGGKGSGSGRKGSDGN--DERGKSLKKRSYFGKLTQ PTEVAGS_657_PE5 NOISO GGHGSGSGQGPGDGHGSGG-GKNSEAGKGSRSGKG-SDGND--EQRKSLKKRSYFGKLTQ RABITX_59_PE3 NOISO GGQGSGGGQGPGDGHGWGR-GKNSEGDKGSGRGKG-SNGDG--DRGKSLKKRSYFGKLTQ RATX_PE348 ENSRNOG00000019011 GGHGSGGGQGPGDGHGSGG-GKNSGGSKGSGSGKN-SDD---GDRGKSVKKRSYFGKFTQ RATX_PE349 ISOFORMIN GGHGSGGGQGPGDGHGSGG-GKNSGGSKGSGSGKN-SDD---GDRGKSVKKRSYFGKFTQ TUPGBGS_903_PE4 NOISO GGYGSGGGQGPGNGRGSRS-GKHSGGGKSSGSEKG-SDGDG--ERGKSLKKRSYFGKLTQ MATCH ..* * .**: : ..: CONSENSUS GGHGSG?GQGPGDGHGSG??GK?SG??KGSGSGK??????????RGKSLKKRSYFGK?TQ

AILMEGL193302_1_PE1 NOISO SKQH-MPP-PPPPPPPPPTAGATGGKGKSGGRFRLYFCADRGAPKERKEAKEAKD-LEIP BOVINX_36_PE2 NOISO SKQQQMPPPPPPP---PPPGAATGGK-------------DRGATKERKEAKEGKD-TEPP CANFAX_87_PE3 NOISO SKQQQMPP-PPPPPPPPPPAGATGGKGKSGGRFRLYFCADRGAQKDRKEAKEVKDKADSP CAVPO46_13_PE3 NOISO GKQQQMGPASAPP---PLSAGPTNGKGK-GGRFRLYFCADRGATKERKDAKEMRD-TEPP DIPORGS_1216_PE4 NOISO SKQQQMLPPPPPPPPPPPPAGATGGKGKSGGRFRLYFCADRGATKERKEVKETRD-TETP ECHTEGS_1467_PE6 NOISO SKHQQMPPPPPPPPPPP------GAKSKSGSRFRLYFCADRGATKQRKESKDARG-VGLP FELCAGS_3812_PE2 NOISO TKQQQMPPPPP-PPPPPPPPGATGGKGKSGGRFRLYFCADRGATKERKEAKEVKE-AETP HORSEX_88_PE4 NOISO SKQQQMPPPP-PPPPPPPPAGATGGKGKSGGRFRLYFCADRGATKERKEAKEVKD-VESP HSX_PE1979 NOISO SKQQQMPP-PPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKD-AEIP LOXAF32_24_PE1 NOISO SKQQQMP-------------GATGGKGKSGGRFRLYFCADRGATKERKEPKDVKE-AETS MACEUSCAFFOLD7292_PE1 NOISO MQQKT---------------TQLLLDEDSAGNPRLYFLVVTSRETPKL---------EYG MACMUX_110_PE2 NOISO SKQQHMPP-PPPPPPPPPPAGATGGKGKSGGRFRLYFCADRGATKERKEAKEVKD-AEIP MICMUGS_492_1_PE8 NOISO SKQQQMSGPP-PPPPPPPPAGATGGKGKSVGRFRLYFCADRGATKERKEAKEVKP-AEIP MOUSEX_PE1785 NOISO SKQQQTLPP---PPPPPPAAGATGGKGKSGGRFRLYFCADRG-TKERKEAKEVRD-METS MYOLUGS_2407_PE1 NOISO SKQQQMPPPPP-PPPPPPPAGATGGKGKSGGRFRLYFCADRAATKERKEVKD----TETL OCHPR47473_PE1 NOISO SKPLLP---PPPPPPSPPGAGAISAKAKSGGRFRLYFCADRGATKERKEAKELKD-GEIP OTOGAGS_3120_PE3 NOISO SKPQQIPPPPP-PPPPSPPTGATAGKGKSGGRFRLYFCADRA-AKERKEAREMKD-PEIP PIGX_90_PE1 NOISO SKQQQMPP-PPPP---PPPAAATGGKGKSGGRFRLYFCADRGAPKERKETKEVKV-TENP PONPYX_109_PE1 NOISO SKQQQMPP-PPPPPPPPPPAGATGGKGKSGGRFRLYFCADRGATKERKEAKEVKD-AEIP PROCAGS_1337_PE5 NOISO SKQQHMPPPPP-PLPPPPPPGATGGKGKSGGRFRLYFCADRGATKERKESKDVKE-AEAP PTEVAGS_657_PE5 NOISO SKQQHMPPPTL-PPPPPPPAVGTGGKGKSGGRFRLYFCADRRATKERKEAKEIKD-AEIS RABITX_59_PE3 NOISO SK--QMPPPPAPPPPPPPAAGAAVGKGKSGGRFRLYFCADRGATKERKEAKELKD-LETP RATX_PE348 ENSRNOG00000019011 SRCLHPHRR---R----QQLEQLVAKGSLGGDSDFIFAQTEA-QKNAK-----KP-KRTS RATX_PE349 ISOFORMIN AASTPTAAA---S----S-WSNWWQSADRGT-------KERK-EAKEV-----RN-METS TUPGBGS_903_PE4 NOISO SKQQQMPPPPP-PPPLPPSVGTTGGKGKTGGRFRLYFCTDRGATKERKEVREVRE-AETL MATCH . CONSENSUS SK??????????P???P???????GKGKSGGRFRLYFC?DR?A?KERKE?K??????E??

AILMEGL193302_1_PE1 NOISO EGAAQGPHRARAFEE--DEDDPYVPMRPGVAAPLTSSSDYMPMAPQNFSAS-RRHSR-SP BOVINX_36_PE2 NOISO EGAARGPHRARAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNVSVSKKRHSR-SP CANFAX_87_PE3 NOISO EGAARGPLRARAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNFSAS-KHHSR-SP CAVPO46_13_PE3 NOISO GSTALGSHRVRAFDE--DEDDPYVPMRPGVTA-LSSSSDYMPMAPQNVSASKKCHSR-SP DIPORGS_1216_PE4 NOISO ESAARAPYRPRAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNVSASKKHHSR-SP ECHTEGS_1467_PE6 NOISO EGAARCPHRARAFDDDDDEDDPYVPMRPGVAAPLASSSDYMPMAPQNVPLP-KRHSR-SP FELCAGS_3812_PE2 NOISO EGAARGPHRARAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNFSAS-KRHSR-SP HORSEX_88_PE4 NOISO EDAARGPHRVRAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNVSASEKRHSR-SP HSX_PE1979 NOISO EGAARGPHRARAFDE--DEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSR-SP LOXAF32_24_PE1 NOISO EGAARYPHRARAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNVSASKKRHSR-SP MACEUSCAFFOLD7292_PE1 NOISO ENGPTG------TKRNKAEDEGYMPMMPGVAASLKNNSDYLPMAPKSASASKPNSSWSSS MACMUX_110_PE2 NOISO EGAARGPHRARAFDE--DEDDPYVPMRPGVAAPLVSSSDYMPMAPQNVSASKKRHSR-SP MICMUGS_492_1_PE8 NOISO EGAARGPYRARAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNASAS-KRHSR-SP MOUSEX_PE1785 NOISO GGATRGPYRARAFDE--DEDDPYVPMRPGVAAPLACSSDYMPMAPQNSSASTKRHSR-SP MYOLUGS_2407_PE1 NOISO EGAARGPHRARAFHE--DEDDPYVPMRPGVAAPLESSSDYMPMAPQNVSASVKYHSR-AS OCHPR47473_PE1 NOISO EGAARVPYRARAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNASASQKRHSR-SP OTOGAGS_3120_PE3 NOISO EGAARGPYRPRAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNVSAS-KRHSR-SP PIGX_90_PE1 NOISO EGAARGPHRARAFDE--DEDD--------------------------------------- PONPYX_109_PE1 NOISO EGAARGPHRARAFDE--DEDDPYVPMRPGVAAPLVSSSDYMPMAPQNVSASKKRHSR-SP PROCAGS_1337_PE5 NOISO EGAARCPHRARAFDE--DEDDPYVPMRPGVAAPLATSSDYMPMAPQNAP---KRHSR-SP PTEVAGS_657_PE5 NOISO QDAARSSHRARTFDE--DEDDPYVPMRPGVAAPLASSSDYMSMAPQHVSASKRLHSR-SP RABITX_59_PE3 NOISO EGAARGLHRARAFDE--DEDYAYMPMRPGVAASLASSNDYMPMAPQNVSASLKRHSR-PP RATX_PE348 ENSRNOG00000019011 QGTTRGSLRARALYE--DEDDPYVPMRPGVAAPLACSSDYMPMAPQNSSAPTKRHSK-SP RATX_PE349 ISOFORMIN QGTTRGSLRARALYE--DEDDPYVPMRPGVAAPLACSSDYMPMAPQNSSAPTKRHSK-SP TUPGBGS_903_PE4 NOISO EGASCGPQRARAFDE--DEDDPYVPMRPGVAAPLASSSDYMPMAPQNVSASKKRHSR-SP MATCH . . ** CONSENSUS EGAAR???RARAFDE??DEDDPYVPMRPGVAAPL??SSDYMPMAPQN?SAS?K?HSR?SP

AILMEGL193302_1_PE1 NOISO FEDSRGYMMMFPTVSPP-PAPSPPKEPD-PEKEDESKDN--DSESDYMFMAPGAGAIPKN BOVINX_36_PE2 NOISO FEDSRGYMMMFPRVSPP-PVPSPPKEPD-PAKEDDSKDN--DSDSDYMFMAPGAGAIPKN CANFAX_87_PE3 NOISO FEDSRGYMMMFPRMSPP-PAPSAQKEPD-PEKEDESKDN--DSESDYMFMAPGAGAIPKN CAVPO46_13_PE3 NOISO FEDSKGYMMMFPRVSPL-PTQSAPKTPD-PNKEDDSKDN--DSDSDYMFMAPGAGAIPKN DIPORGS_1216_PE4 NOISO FEDSRGYMMMFPRVSPP-PAPSPPRAPDDPNKEDDSKDN--DSDSDYMFMAPGAGAIPKN ECHTEGS_1467_PE6 NOISO FEDSRGYMMMFPRVSPP-SVPSPPKTPD-ANKEDDSKDNDNDSDSDYMFMAPGAGAIPKN FELCAGS_3812_PE2 NOISO FEDSRGYMMMFPRESPP-PAPSPPKEPD-PDKDDEAKDN--DSDSDYMFMAPGAGAIPKN HORSEX_88_PE4 NOISO FEDSRGYMMMFPRVSPP-SAPNPPKAPD-PEKEDDSKDN--DSDSDYMFMAPGAGAIPKN HSX_PE1979 NOISO FEDSRGYMMMFPRVSPP-PAPSPPKAPD-TNKEDDSKDN--DSESDYMFMAPGAGAIPKN LOXAF32_24_PE1 NOISO FEDSRGYMMMFPRASPP-PAPTPPKEPE-PNKEDDSKDN--DSDSDYMFMAPGAGAIPKN MACEUSCAFFOLD7292_PE1 NOISO QKDSRGYMMMFPRASLSPGRNSRGRFT-------SKGASNKDDDNEYMDMSPRNPIAPKS MACMUX_110_PE2 NOISO FEDSGGYMMMFPRVSPP-PAPSPPKAPD-TNKEDDSKDN--DSESDYMFMAPGAGAIPKN MICMUGS_492_1_PE8 NOISO FEDSRGYMMMFPRVSPP-PVPSPPKTPD-PNKEDDSKDN--DSDSDYMFMAPGAGAIPKN MOUSEX_PE1785 NOISO FEDSRGYMMMFPRVSPPPPVPSAPKAPD-TNKGDDSKDN--DSDSDYMFMAPGAGAIPKN MYOLUGS_2407_PE1 NOISO FEDSRGYMMMFPRVSPP-PAPIPPKASD-PDKKDDSKDN--DSDSDYMFMAPGAGAIPKK OCHPR47473_PE1 NOISO FEDSRGYMMMFPTTSPP-PAPSPPKAGD-LNKDDESKD---DSDSDYMFMAPGAGAVPKN OTOGAGS_3120_PE3 NOISO FEDSRGYMMMFPRVSPP-PVPSPPKTPD-PDKEDDSKDNDNDSDSDYMFMAPGAGAIPKN PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO FEDSRGYMMMFPRVSPP-PAPSPPKAPD-TNKEDDSKDN--DSESDYMFMAPGAGAIPKN PROCAGS_1337_PE5 NOISO FEDSRGYMMMFPRASPP-RAPSPPKEPE-PDKDDDDKDN--DSDSDYMFMAPGAGAIPKK PTEVAGS_657_PE5 NOISO FEDSRGYMMMFPRVSPP-PAPSPPKAPD-PDKEDDSKDN--DSDSDYMFMAPGAGAIPKK RABITX_59_PE3 NOISO FEDARGYMMMFPRESPP-PAPSPPKAAD-PNKEGDSKD---DGDSDYMFMAPGAGAIPKN RATX_PE348 ENSRNOG00000019011 FEDSRGYMMMFPRVSPPPPAPSARKAPD-THKEDDSKDN--DSDSDYMFMAPGAGAIPKN RATX_PE349 ISOFORMIN FEDSRGYMMMFPRVSPPPPAPSARKAPD-THKEDDSKDN--DSDSDYMFMAPGAGAIPKN TUPGBGS_903_PE4 NOISO FEDSRGYMMMFPRVSPP-PAPSPPKAPD-PNKEDDSKDN--DSDSDYMFMAPGAGAIPKN MATCH CONSENSUS FEDSRGYMMMFPR?SPP?P?PS?PK?PD???K?D?SKDN??DS?SDYMFMAPGAGAIPKN

AILMEGL193302_1_PE1 NOISO PPNPQGGSSSKSWSSYFSLPNAFQGSPLGQSEHSEYVPMLPGKVLGKGLDKEASSNGGPK BOVINX_36_PE2 NOISO PRNPQGGSSSKSWSSYFSLPNPFRSSPLGQSDHSEYVPMLPGKFLGKGLEKEVSSNRGPK CANFAX_87_PE3 NOISO PRNPQGGSSSKSWSSYFSLPNPFQGSPLGRSDHSEYVPMLPGKFLGNSLDKAPTSNWGPK CAVPO46_13_PE3 NOISO PRNPQGGSSSKSWSSYFSLPNLFQSSPLGQSDHSEYVPMLPGKFLGQG--KEISSNWGLK DIPORGS_1216_PE4 NOISO PRNPQGGSSSKSWSSYFSLPNPFQSSPLGQSDHSEYVPMLPGKYLGKGLDKETSSNKGPK ECHTEGS_1467_PE6 NOISO PRNSQGGSSSKSWSSYFSLPNPFRGSPLGQ---SEYVPMLPGKFLGRGPHKESSANGAPK FELCAGS_3812_PE2 NOISO PPNPQGGSSSKSWSSYFSLPNPFQGSPLGQSDHSEYVPMLPGKFLGKGLDKESSSNRGPK HORSEX_88_PE4 NOISO PRNPQGGSSSKSWSSYFSLPNPLQSSPLGQSDHSEYVPMLPGKLLGKGLDKEASSQGDPK HSX_PE1979 NOISO PRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPK LOXAF32_24_PE1 NOISO PRSPQGGSSSKSWSSYFSLPDPFQSSPLGQNDHSEYVPMLPGKFLGRGPDKEASFNRGPK MACEUSCAFFOLD7292_PE1 NOISO PMSLHPPSFSKSLSSLFSLPKSFRTIT-EQSDDSDYVPMASPGRLLSTVSENVKGTLKPS MACMUX_110_PE2 NOISO PRNPQGGSSSKSWSSYFSLPNPFQSSPLGQSDNSEYVPMLPGKFLGRGLDKEVSYNWGPK MICMUGS_492_1_PE8 NOISO PKNAEGGSSSKSWSSYFSLPNPFRSSPLGQSDHSEYVPMLPGKFLGRGLEKEVSSNWGTK MOUSEX_PE1785 NOISO PPNAQGGSSSKSWSSYFSLPSPFQSSPLGQSDHSEYVPMLPGKFLGSGLHKEASFSQGTK MYOLUGS_2407_PE1 NOISO PPNPQGGSSSKSWSSYFSLPKTFRSSPLGQSDHSEYVPMLSGKLLGKGLDKEASSIRGPK OCHPR47473_PE1 NOISO PQNPQGGASSRSWNSYFSLPNPFRNSPLGQSDHSEYVPMLPGKLLGRGLNKEVSSNWGSK OTOGAGS_3120_PE3 NOISO PRNPQGGSSSKSWSSYFSLPNPFRSSPL-QSDRSEYVPMLPGKSLGRGLDKEA-SNWGPD PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO PRNPQGGSSSKSWSSYFSLPNPFRSSPLGQSDNSEYVPMLPGKFLGRGLDKEVSYNWGPK PROCAGS_1337_PE5 NOISO PRNPQGGSSSKSWSSYFSLPNHFRGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_657_PE5 NOISO PRNPQGGSSSKSWSSYFSLPNPLQSSPLGQSDHSEYVPMLSGKLLGKGLDKETSSIRGPK RABITX_59_PE3 NOISO PKNPQGGASSKSWSSYFSLPNPFRSSSLGQSDHSEYVPMLPGKFLGRGSDKEVSSNWGPQ RATX_PE348 ENSRNOG00000019011 PPNPQGGSSSKSWSSYFSLPSPFQSSPLGQSNHSEYVPMLPGKFLGSSLDKHASFSQGTK RATX_PE349 ISOFORMIN PPNPQGGSSSKSWSSYFSLPSPFQSSPLGQSNHSEYVPMLPGKFLGSSLDKHASFSQGTK TUPGBGS_903_PE4 NOISO PRNPQGGSSSKSWSSYFSLPNPFRSSPLGQSDHSEYVPMLPGKFLGRGLDKKAPSNWGPK MATCH CONSENSUS P?NPQGGSSSKSWSSYFSLP??F??SPLGQS??SEYVPMLPGK?LG????K????????K

AILMEGL193302_1_PE1 NOISO DALSKPSAQGSFSKPGDGGSPSKPSDDGPPKNKAKRPNRLSFITKGSKIKPK--SQKPTH BOVINX_36_PE2 NOISO --------------PRDGGSPSKRSGDGPPKNKAKRPNRLPFMTKGNKVKPK--PQKPTQ CANFAX_87_PE3 NOISO HAVSKPPVEGSFSKPRDGGTCWKPSDNGPPKNKAKRPNRLSFITKGNKIKPK--SQKPTR CAVPO46_13_PE3 NOISO DRASKPMLEGSFSNSGDGRSSSKPSNGGPPKNKAKRPNQLAFITKGNKIKPI--PQK--- DIPORGS_1216_PE4 NOISO DAPSKPSAQGSFSKPRDGGSSLKPSDDEPPQNKAKRPSRLSFITKGNKIKPK--PQKSTR ECHTEGS_1467_PE6 NOISO DAPSEPSVQGSISRPERGGSSSKPSDDGPPENKAERPNSLAFITQGNVIKPK--PPKPTR FELCAGS_3812_PE2 NOISO DAVSKPSVEGSFSKPGD---------NSPSKNKAKRPNHLSFITKGNKIKPK--SQKPTR HORSEX_88_PE4 NOISO DAASKPSVERSFSKPGDGGSPSKPSDESPPKIKAKRPNRLSFITKGNKIKPK--PQKPTR HSX_PE1979 NOISO DAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPK--PQKPTH LOXAF32_24_PE1 NOISO DAPSKPLDQGFCPEPGDGGSPSKPSDDGPPKNKAKRPNRFSFITKGNKIESK--PQKPTQ MACEUSCAFFOLD7292_PE1 NOISO PK---------FLK-----PALKGSDGGFPQRKAARPTKLLLGTRGSSIPRI------YE MACMUX_110_PE2 NOISO DAASKPSGEGSFSKPGDGGSPSKPWDDGSLKNKAKRPNRLSFITKGYKIKPK--PQKPTR MICMUGS_492_1_PE8 NOISO HAASKPSVEGLFSKPADRGAPSKPLDDGPPKNKAKRLNRLSFITKGNKIKPK--PQKPTH MOUSEX_PE1785 NOISO NVSSKPSTEASFSKPEDKGSSAKPSDDVPPMNKAKEPNHLSFIAKGTQVKPK--PLNPTQ MYOLUGS_2407_PE1 NOISO YAASKPSVEGSVSKPGDGSSPSKPSDDGPPKDQAKRPNQLSFMTKGNKIEPK--TQKPTR OCHPR47473_PE1 NOISO DTTSKPPAEGSFPKPGGGESPSKPSDDRPPR-KAKRPKVVSLVTKVTKLRPKTKPQKARS OTOGAGS_3120_PE3 NOISO HAANQ-PVEGLFSKPGEGESPSKPXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXX PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO DAASKPSGEGSFSKPGDGGSPSRPSDDEPPKNKAKRPNRLSFITKGYKIKPK--PQKPTH PROCAGS_1337_PE5 NOISO XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXPKNAKRPIRLSFIIKGNKVKP-------TH PTEVAGS_657_PE5 NOISO DAVSEPSLEGSFSKPGDGGSPSKPSDDESPKNKTKRPNQLSFIAKGNKIKPK--PQKLLC RABITX_59_PE3 NOISO DTGPKPSVEGSHSKPRNGGAPLKPSDDGPPKNKAKRPNRLSLMIKGNTMKPK--LQKPRS RATX_PE348 ENSRNOG00000019011 DVASKPSTEGSFSKPEDKGSSARPSDDVPPMNQAKEPNRLSFIAKGNKIKPR--PLNPTQ RATX_PE349 ISOFORMIN DVASKPSTEGSFSKPEDKGSSARPSDDVPPMNQAKEPNRLSFIAKGNKIKPR--PLNPTQ TUPGBGS_903_PE4 NOISO DAASKSSTEGPFTKPGEGGSRSKPSDDGPPKNKAKRPNRLSFITKGNKVKPK--PRKPTR MATCH CONSENSUS ??????????????P????????P?????P???AKRP??L?F??KG????P?????????

AILMEGL193302_1_PE1 NOISO EQRGAVSSSDYVNIDFTKRESNVPAP-FIYGLPGSWGIIAGPRPSAFSNYVNIEFGLPFP BOVINX_36_PE2 NOISO EQREADSPRGYVNIDFPKRGYNMPDP-CLQRLPGVWGIIADPRQFAFSNYVNVEFGVPFP CANFAX_87_PE3 NOISO AQREADSSSVYVNIDFTKSGSNMPAP-FIQGLPGSWGIMAGPRPSAFSHYVNVEFEVLFP CAVPO46_13_PE3 NOISO -QREVDSFSGYVNIDFTKRDS-MPAP-SAQGLPHSLGIIADPRQSAFSNYMNAEFRVPFP DIPORGS_1216_PE4 NOISO ELRETDRASAYVNIDFTKRDRNLPTP-FAQALPNSWGIIAGPRHSAFSNYFSVRLGVPFP ECHTEGS_1467_PE6 NOISO RQREADYS-IYYFIDFIKREDIPPGP-SPRKLPASWXXXXXXXXXXXXXYMNVEFGVPLP FELCAGS_3812_PE2 NOISO EQREADSSGDYVNIDFTKRDTNMPAP-FIQGLPGSWSIIAGPRPSAFSNYVNVEFRVPFP HORSEX_88_PE4 NOISO EQREADSSSGYVNVDFTKRDSNTPAP-STQGLPGLWGIIADPRRSVFSNYVNVEFGVPFP HSX_PE1979 NOISO EQREADSSSDYVNMDFTKRESNTPAP-STQGLPDSWGIIAEPRQSAFSNYVNVEFGVPFP LOXAF32_24_PE1 NOISO EQRGADSSSDYVNIDFTERESNTPVR-STQRLPDSWGVIADRRQSASSRYVNLQFGVPFP MACEUSCAFFOLD7292_PE1 NOISO RAIEGDSPGEYINIDFSRKAGNTSYSLSAECSPSSFGSSSDHTQSPFSDYMSFALDVNSP MACMUX_110_PE2 NOISO EQREADSSPDYVNIDFAKRESNTPAP-STQGLPGSWGIIADPRQSAFSNYVNVEFGVLFP MICMUGS_492_1_PE8 NOISO EQREADGSSDYVNIDFTKRDSNRPVP-FIQGLPDSWGIIVDPRQSAFYNYVNVEFGVPFL MOUSEX_PE1785 NOISO ERREAAGSRDYINIDFIKRERLVLPS-SAQGLPDMRGVVTDPAPTAFSGYLNVEFGVPFP MYOLUGS_2407_PE1 NOISO EQREADSSSDYVNLDFTERSSNMPAP-VTQGLPHSWGIIANPRQSAFSHYMNIEFRVPFR OCHPR47473_PE1 NOISO EQKAGGWSSDSVRLDCTLIASHAPVP-STQAVLAWWGVLANARPSALSNSLYMELGMSFP OTOGAGS_3120_PE3 NOISO XXXXXXXXXXXVNIDFTERDSDMPAP-SPQGLPGSWGIIANPRQSAFSPYVNVEFGVPFP PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO EQREADSSSDYVNMDFTKRESNTPAP-STQGLPDSWGIIAEPRQSAFSNYVNVEFGVPFP PROCAGS_1337_PE5 NOISO EQRGADSSSDYVNIDFTERERNMPAS-STQRLPDSWGVIADPRQSAFSHYMNLEFGVPLP PTEVAGS_657_PE5 NOISO EQGEADSSSDYVNTDFTKRNSNMLVP-FTQGLPHSWGVIADPRQSAFSHYVNIGFRVPFR RABITX_59_PE3 NOISO EQRQA----DYVNADFSERVRNMPAP-STEGLPGSWGAIANPRHSLFSSYLNVEFGVPFP RATX_PE348 ENSRNOG00000019011 EQREADSSNDYINIDFVKREHLVLAP-SAQGLPEFWGVITNARPSAFSRYVKVEFGAPFP RATX_PE349 ISOFORMIN EQREADSSNDYINIDFVKREHLVLAP-SAQGLPEFWGVITNARPSAFSRYVKVEFGAPFP TUPGBGS_903_PE4 NOISO EQREADSSSDYINIDFTKRDSNRPAP-PTQGLPDSWGIIADLRQSAFSHYMNVEFGVPFP MATCH CONSENSUS ?QR???????Y?N?DF??R??????P???Q?LP??WG?????R?SAFS?Y???EF?VPFP

AILMEGL193302_1_PE1 NOISO NAAHRLSNL-LR--AIPGANPVYLEGARWPLA-PLLRSATGGSASEEEGDYIEVIFNPAM BOVINX_36_PE2 NOISO ------------------------------------------------------------ CANFAX_87_PE3 NOISO HPAQNFSHL-FR--AIPGANPLFLEGARWPLV-PLPPSATGGSASEEEGDYIEVIFNPAM CAVPO46_13_PE3 NOISO NPASHLSDL-LR------ANPLSLDGARWPFP-PLPPRATGGNVSVEESDYIEVIFNPAM DIPORGS_1216_PE4 NOISO NPASRLSDL-LR--AIPGANPFSLDGARWPHP-SIPVSAPSSNANVEEGDYIEVIFNPAM ECHTEGS_1467_PE6 NOISO KAASHLANL-LR--AIPGANPPSLEGAQRPPPPPPPPGATGGNASAEEGEYIEVIFSPAM FELCAGS_3812_PE2 NOISO NPAHSLSNL-LR--AFPGANPLFLEGARWPFV-PLPPSATGGNANEEEGDYIEVIFNPAM HORSEX_88_PE4 NOISO NPGNDLSHL-LR--AIPGANPLFLDGARWPLL-PLPPSATGSNANEEEGDYIEVMFNPAM HSX_PE1979 NOISO NPANDLSDL-LR--AIPRANPLSLDSARWPLP-PLPLSATGSNAIEEEGDYIEVIFNSAM LOXAF32_24_PE1 NOISO YPANNFSNL-IR--VIPGAIPPSLDGARWPLP----PSATGGNA-EEEGEYIEVIFNPAM MACEUSCAFFOLD7292_PE1 NOISO KAAKELANSLTISGSNLPRNQLTVDCARRPLG----AAARVSTPTNGDDDYTEMTFNPAG MACMUX_110_PE2 NOISO NPANDFSDL-FR--AIPRANPLSLDSARWPLP-PLPLSATGSNANEEEGDYIEVIFNSAM MICMUGS_492_1_PE8 NOISO NSN----DL-LY--LLRGAGPLFLDGTRWPLR-LVPLSATGSNANEEEGDYIEVIFNPAM MOUSEX_PE1785 NOISO NPTIRLSDL-LR--VLPGANSIPLAGTRWPFP-GS---AIG--SIVEAGEYIEVIFNPAM MYOLUGS_2407_PE1 NOISO NATNVLSNL-LR--AIPGANRFFLDSTR-PLL-PLLNSATGSNANEEECEYIEVTFNPAM OCHPR47473_PE1 NOISO NPGNALSDI-LG--VIPGATPLSLAGARWPLP-PLPPWATGSNANEEEGDYIEVIFNPAM OTOGAGS_3120_PE3 NOISO NPASNFSDL-LR--AIPGANPLFLDGARWPLL-PLPPSATGSNANEEEGDYIEVIFNPAM PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO NPANDLSDL-LR--AIPRANPLSLDSARWPLP-PLPLSATGSNANEEEGDYIEVIFNSAM PROCAGS_1337_PE5 NOISO YPASNLPNL-LR--IIPGANPQFLNGARWPLP-PLRPSATGGNS-EEEGNYIEVIFNPAM PTEVAGS_657_PE5 NOISO NPANDLSNI-LR--AITGANLFSLDGARWPLL-PLLSSATGSNANEEECDYIEVIFNPAM RABITX_59_PE3 NOISO NPANTLSDLFLR--AMPGANPFSLDGARWPLP-LLPLRATGSNANGDEGDCIKVIFNPAM RATX_PE348 ENSRNOG00000019011 NPTVRLSEL-L------------------------------------------------- RATX_PE349 ISOFORMIN NPTVRLSEL-L------------------------------------------------- TUPGBGS_903_PE4 NOISO NPGNHLSHL-LR--AIPGANPLSLDGARWPL----PPSATGRNANEEEGDYIEVIFNPAM MATCH CONSENSUS ????????L?????????A????L???R?P????????A???????????YIEV?FN?AM

AILMEGL193302_1_PE1 NOISO TPIVPFGDSAIR---YDAQ---TGRIYVVDPFSECCMDISLSPGRYSEPPPVARLLQEEQ BOVINX_36_PE2 NOISO ------------------------------------------------------------ CANFAX_87_PE3 NOISO TPAVPFGDSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEQ CAVPO46_13_PE3 NOISO TPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPTRCSESPLVARLLQEEE DIPORGS_1216_PE4 NOISO TPPVPFADRTIR---YDAE---TGRIYVVDPFSECCMDISLSPSRSAEPTPVARLLLGEV ECHTEGS_1467_PE6 NOISO TPAVPFAESAIR---YDAE---TGRIYVVDPFSECCMNISLSPSRCSEPPPVARLLQDEE FELCAGS_3812_PE2 NOISO TPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQED- HORSEX_88_PE4 NOISO IPAVPFADRAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLLEEE HSX_PE1979 NOISO TPAMALADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEE LOXAF32_24_PE1 NOISO IPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPLPVARLRQEEE MACEUSCAFFOLD7292_PE1 NOISO TTTVPFAAQSNDPVKIDSPSSAVNRLRIADTSPEGSSPFLISP-----EPSVVPMVVRAD MACMUX_110_PE2 NOISO TPVMPLADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEE MICMUGS_492_1_PE8 NOISO TPFVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVVRLLQEEE MOUSEX_PE1785 NOISO TPAMSFADSAIC---YDAQ---TGQIYVVDPFSECCMDVSLSPGRCSEPPPVARLRREEA MYOLUGS_2407_PE1 NOISO APALPFGDRAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEE OCHPR47473_PE1 NOISO TPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDVALSPSPCSDPPPVARLLQEEE OTOGAGS_3120_PE3 NOISO TPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQHEE PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO TPAMALADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQQ-E PROCAGS_1337_PE5 NOISO IPAVPFGDSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLLEEE PTEVAGS_657_PE5 NOISO TPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPAPVARLLQEEV RABITX_59_PE3 NOISO TPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISRSPSRCSDPPPVARLLQEEE RATX_PE348 ENSRNOG00000019011 ------------------------------------------------------------ RATX_PE349 ISOFORMIN ------------------------------------------------------------ TUPGBGS_903_PE4 NOISO TPAVPFADSAIR---YDAE---TGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEE MATCH CONSENSUS ?P????????I????YDA????TGRIYVVDPFSECCM????SP????????V?RL?????

AILMEGL193302_1_PE1 NOISO -PQRRRPQSRSQSFFGSARAAVSAFPTDSLERDLSAPFASAAAAS---AAVPAL------ BOVINX_36_PE2 NOISO ------------------------------------------------------------ CANFAX_87_PE3 NOISO QLERRRPQDRSQSFFPSARAAVSAFPTDSLERDLPASLASAAAAAAASAAAPALALGRAL CAVPO46_13_PE3 NOISO -QETRCSQSPSQSFFAAARAAVSAFPTDSLQREISASLSSA----PAAAAAPTLEVGRLL DIPORGS_1216_PE4 NOISO -HESERPQSRSQSFFLAARAAVSAFPTDSLERDLAAAS------PAARATIPPLALGQAI ECHTEGS_1467_PE6 NOISO -PRRRRPRSRSRSSFAGSRGAVSAFPTDSLERELGAAA--------AAAAAPTLAVGRAL FELCAGS_3812_PE2 NOISO GLERRRPQSHSQSFFASARAAVSAFPTDSLERDLSASLAS--------VAAPALAVGRAL HORSEX_88_PE4 NOISO -LERRRPQSRSQGFFASTRAAVSAFPTDSLERDLSASLASA----AALAAAPTLGVGRAL HSX_PE1979 NOISO Q-ERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAP----AVASAAEPTLALSQVV LOXAF32_24_PE1 NOISO -QERRRPQSRSRSFFAGARAAVSAFPTDSLERDLSAFLASA-------AAAPTLVVGRAL MACEUSCAFFOLD7292_PE1 NOISO PQGRRRHSS--ETFSAAGAVATISFLI--------------------------------- MACMUX_110_PE2 NOISO Q-ERRRPQNRSQSFFAAARAAVSAFPTDSLERDLSPSSVP----AVTSAAEPTLAVSQVV MICMUGS_492_1_PE8 NOISO -RERRRPQSRSQSFFAAARAAVSAFPTDSLEGELSASPASA----AAFAAAPTLAVGRVL MOUSEX_PE1785 NOISO -QERRRPQSRSQSLFASTRAAVSAFPTDSLDRDFPAASAVI----AAPAEAPLLAVSRAL MYOLUGS_2407_PE1 NOISO --LERSPQSRSQSVFASTRAAVSAFPTDSLERDLYTSRGST----SAVGSEPTLAVGRAL OCHPR47473_PE1 NOISO -QGRRHPPSRPETLFAAARAAVSAFPTDSLDRDLSASSAS--------AAAPTLAVGRAL OTOGAGS_3120_PE3 NOISO -QNRRRPQSRSQSFFAASRAAVSAFPTDSLEGDLSAFSAVA-----AGLAATPLAVGRAL PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO Q-ERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAP----AVASAAEPTLALSQVV PROCAGS_1337_PE5 NOISO -QENRRPRSQPQSFFAGARAAVSAFPTDSLESELSASLASA----VAAAAGPTLAVGRAL PTEVAGS_657_PE5 NOISO -LERRRPQSRSLSFFASVRSSISALPTDSLERDLYASFASA----AVAVVVPTFALGRAL RABITX_59_PE3 NOISO -HGRRHPPSRSQTFFAAARTAVSAFPTDSLDRDLSASSAPA----AAWAAAPTLAVGRAL RATX_PE348 ENSRNOG00000019011 ------------------------------------------------------------ RATX_PE349 ISOFORMIN ------------------------------------------------------------ TUPGBGS_903_PE4 NOISO --QERRPQSRSQSFFAATRAAVSAFPXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXX MATCH CONSENSUS ????R?????????F???R?A?SAFP??????????????????????????????????

AILMEGL193302_1_PE1 NOISO -----ALSAPGIGAAARGLDAAAGFDSAS--VRWFRPVAGAAAA----EAVRGAQNVA-S BOVINX_36_PE2 NOISO ------------------------------------------------------------ CANFAX_87_PE3 NOISO AAASALAAAPGIGAAARGLEAAAGFDSAS--VRWFQPVAGSAAAAA--AAVRGTQAV-AA CAVPO46_13_PE3 NOISO AAASVLTVVPGLGAAAQVLEAAVGFDSASASAGSFQPVANA------------------- DIPORGS_1216_PE4 NOISO AAASALAAAPGMGAAAAGLEAAAGFDSAS--TRWLQPVANVL--EA--EAVNRAQSV-AR ECHTEGS_1467_PE6 NOISO AAASVLAAVPGLGAAAAGLEAA-GFDS----ARWFLPVANAAAA----ETVRGFQNL-AG FELCAGS_3812_PE2 NOISO AAASALAAAPGIGAAARGLEAAAGLDSAS--VRRFQPVASAA--AA--EAVRGAPDV-AR HORSEX_88_PE4 NOISO AAASALAAAPGIGAAASGFEAAAGFDSAS--VRWFQPVANAA--DA--EAVMGAQDV-AS HSX_PE1979 NOISO AAASALAAAPGIGAAA----AAAGFDSAS--ARWFQPVANAA--DA--EAVRGAQDV-AG LOXAF32_24_PE1 NOISO AAASALAAAPGIGAAAAGLEATAGFDSAS--ARWFLPVANAAAAA-AAEAIRGFQNI-AE MACEUSCAFFOLD7292_PE1 NOISO ------------------------------------------------------------ MACMUX_110_PE2 NOISO AAASALAVARGIGAAA----AAAGFDSAS--ARWFQPVANAA--DT--EAVRGAQDV-AG MICMUGS_492_1_PE8 NOISO AAASALAAAPSIVA--ASWEAAAGLDSAS--VRWFQPVANAA--DA--RAARGTQNS-AF MOUSEX_PE1785 NOISO AVVSALAAAPSIGDVFAGFRAAAGVDSAS--ARGFQPVAGAQ-------AVREFQDL-AA MYOLUGS_2407_PE1 NOISO AAASALAAVPGMGAAAAGFEAASGFNSAS--ACWFQPVANAAGAAAGAEAVRGAH--VVG OCHPR47473_PE1 NOISO AAASALAAAPGIGSAAAAFEAA------AASARWFQ------------------------ OTOGAGS_3120_PE3 NOISO AVASALAVAPGIGSAAAGWEAAFGFNSAS--ARWFPPVANAADA----EAVRGAQDR-AR PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO AAASALAAAPGIGAAA----AAAGFDSAS--ARWFQPVANAA--DA--EAVRGAQDV-AG PROCAGS_1337_PE5 NOISO AAASTLAAAPGMGAAASGLGAAPGFDPAY--AGWILPVANAADA----EALRGFQNA--G PTEVAGS_657_PE5 NOISO AAASALAAAPGLGAAAAGFQAASGFNSAS--VRWFQLVANAA--GA--EAVRGSQVF-AC RABITX_59_PE3 NOISO AAASALAAAPGIGAAAASFEAAAGFDSAS--ARWFQPVVAAAAAAA--AAAAAAAAAAAD RATX_PE348 ENSRNOG00000019011 ------------------------------------------------------------ RATX_PE349 ISOFORMIN ------------------------------------------------------------ TUPGBGS_903_PE4 NOISO XXXXXLAAAPGIGAAAGAFEAVAGFDSAS--ARSFQPVGNAA--DA--LAVRGAQDI-AP MATCH CONSENSUS ????????????????????A???????????????????????????????????????

AILMEGL193302_1_PE1 NOISO GSSP----QPVDLAGGENRAAA---------AAPPPPPRRPVPSPPELEESDNDD-DDDD BOVINX_36_PE2 NOISO ------------------------------------------------------------ CANFAX_87_PE3 NOISO GSNPRARHPSADLAGGENWATAAVS--P---PPPPPPPRRPVPSPPEQQVSDNDDDDDDD CAVPO46_13_PE3 NOISO ------------------------------------------------------------ DIPORGS_1216_PE4 NOISO GSNPGAPNPAADLAGGENVAGGAAAAAAAPRPPPPPPRHGRVPRPPQRADSDNNDNDDDE ECHTEGS_1467_PE6 NOISO GSNPRAPNAAADRARRASGARGGAGAAAVP-PSPPPRRRRPVPRPRVQA-----ESDEDD FELCAGS_3812_PE2 NOISO GSNPRAPNPDADLARDENGAAAA--------APPPPPPRRRVPIPRERE-----DSDDDD HORSEX_88_PE4 NOISO GSNPRAQNPSSDLDGDEDGTGEAAAAAA----VPPTPPRRQMPRPPEQE-----DSDDDD HSX_PE1979 NOISO GSNPGAHNPSANLARGDNQAGGAAAAAA---APEPPPRSRRVPRPPERE-----DSDNDD LOXAF32_24_PE1 NOISO DWNPEGSNPSADPARGENEAS-------------------PVPRPPERE-----DSDDDD MACEUSCAFFOLD7292_PE1 NOISO ------------------------------------------------------------ MACMUX_110_PE2 NOISO GSNPGAHNPSANLARGENQAGGAAAAAA---APEPPPRSRRVPRPPERE-----DTDDDD MICMUGS_492_1_PE8 NOISO AWNLGAPNPPADLARGENGAGGAAAAAA---APPPPPRGPRVPRPPERGDS---DDDDDD MOUSEX_PE1785 NOISO GWNPGALNHR---ARGEDLAAGAA-------APPPPPRQIWVLRPQERADSEDD-DDDDD MYOLUGS_2407_PE1 NOISO GSNPRAENPSADLARGENGAGEAAAAAA----APPPPPRHWLPRLPEREDS------DEE OCHPR47473_PE1 NOISO ------------------------------------------------------------ OTOGAGS_3120_PE3 NOISO VS-NLGANPSADLVGGENAAGGAAAAAP----VPPPPPRRWVPRPPEREDSDND-QDDDD PIGX_90_PE1 NOISO ------------------------------------------------------------ PONPYX_109_PE1 NOISO GSNPGAHSPSANLAGGENQAGGAAAAAA---APEPPPRSRRVPRPPERE-----DSDNDD PROCAGS_1337_PE5 NOISO GWNPEAANPPADPAGSQSGAAAAA------AAPPPPPRHGPGPRPQEREDSDD--DDDDD PTEVAGS_657_PE5 NOISO GSSPRAQNPFADLDRGVNLADGAAAAAA----APSPPPHCLVPRLPERE-----DSDDDE RABITX_59_PE3 NOISO AEALSGVQDIADLVRGENGAGRAA-------TPPRPLRRRWVRRPPEREDS------DSD RATX_PE348 ENSRNOG00000019011 ------------------------------------------------------------ RATX_PE349 ISOFORMIN ------------------------------------------------------------ TUPGBGS_903_PE4 NOISO GSNPEAQHLPANLAGCENEAARAA-------APPAPPRRRRVPRPSERE-----DSDNDD MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193302_1_PE1 NOISO ETYVRMDFARPDYKK--------- BOVINX_36_PE2 NOISO ------------------------ CANFAX_87_PE3 NOISO DTYVRMDFARPDNKKSDSPRRGG- CAVPO46_13_PE3 NOISO ------------------------ DIPORGS_1216_PE4 NOISO ATYMRMDYARRDPNKFDSPKRGW- ECHTEGS_1467_PE6 NOISO ETYVRMDFARRDNK-LDSPKRGGS FELCAGS_3812_PE2 NOISO DTYVRMDFARPDNKKFDSPHRGW- HORSEX_88_PE4 NOISO DTYVRMDFARSDNKK--------- HSX_PE1979 NOISO DTHVRMDFARRDNQF-DSPKRGR- LOXAF32_24_PE1 NOISO DTYVRMDFARPDNKK--------- MACEUSCAFFOLD7292_PE1 NOISO ------------------------ MACMUX_110_PE2 NOISO DTYVRMDFTRPDNQF-DSPKRGR- MICMUGS_492_1_PE8 NOISO DIYVRMDFARPDNK-FDSPKRGW- MOUSEX_PE1785 NOISO DIYVRMDFARRDYRK--------- MYOLUGS_2407_PE1 NOISO DTYVRMDFAGPEDK-FDSPQRGW- OCHPR47473_PE1 NOISO ------------------------ OTOGAGS_3120_PE3 NOISO DIYVRMDFARPDKK-FDSPKRG-- PIGX_90_PE1 NOISO ------------------------ PONPYX_109_PE1 NOISO DTYVRMDFARRDNQF-DSPKRGR- PROCAGS_1337_PE5 NOISO DIYVRMDFARPENKKFDSPERG-- PTEVAGS_657_PE5 NOISO DTYARMDFARSDRK-FDSPQRGW- RABITX_59_PE3 NOISO NFYLRMGLVKPD------------ RATX_PE348 ENSRNOG00000019011 ------------------------ RATX_PE349 ISOFORMIN ------------------------ TUPGBGS_903_PE4 NOISO DTYVRMDFARSDNKKFHFPKRGW- MATCH CONSENSUS ????????????????????????


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