Alignment of the gene Family HOG000113190 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL195124_1_PE1 NOISO ------------------------------------------------------------ ANOCA81_1_PE4 NOISO ------------------------------------------------------------ CALJAX_7_PE4 NOISO ---------------MVPGAPGV--VLTLCLWLVASGV--CLA--AGPGAAAARRLD--- CANFAX_6_PE1 NOISO ------------------------------------------------------------ CAVPO126_4_PE1 NOISO ------------------------------------------------------------ CHICK1_PE2112 NOISO ------------------------------------------------------------ DANRE1_32_PE20 NOISO ---------------MRDG------LTGLCIGIILLLN---------GGLVVMRRQD--- DANRE22_43_PE35 NOISO HRLDPHAFTRTSAKMLLLRNLCC-----FLLCCVFE-------------VSVARRT---- DASNOGS_123_PE1 NOISO ---------------MEPGAPGA--ALTLCLWLAASGG--CLA--AGPGA--ARRLD--- FELCAGS_92_PE1 NOISO ------------------------------------------------------------ FUGRU103_PE97 ENSTRUG00000009929 ---------------MFCGSA--SACAALCLWITALMS---------AGSVCARKQD--- FUGRU103_PE98 ISOFORMIN ---------------MFCGSA--SACAALCLWITALMS---------AGSVCARKQD--- FUGRU103_PE99 ISOFORMIN ---------------MFCGSA--SACAALCLWITALMS---------AGSVCARKQD--- FUGRU284_PE18 ENSTRUG00000004145 ---------------MSDDML--AVIPSVSLWIIVLFG---------CGGSARRQADDPD FUGRU284_PE19 ISOFORMIN ---------------MSDDML--AVIPSVSLWIIVLFG---------CGGSARRQADDPD FUGRU284_PE20 ISOFORMIN -------------------ML--AVIPSVSLWIIVLFG---------CGGSARRQADDPD FUGRU284_PE21 ISOFORMIN ------------------------------------------------------------ FUGRU379_PE22 ISOFORMIN -----------VLGVMRACRAGV-----VLLCAALA-------------VSLARRS--SP FUGRU379_PE23 ISOFORMIN -------------GVMRACRAGV-----VLLCAALA-------------VSLARRS--SP FUGRU379_PE24 ISOFORMIN --------------VMRACRAGV-----VLLCAALA-------------VSLARRS--SP FUGRU379_PE25 ENSTRUG00000006504 ---------------MRACRAGV-----VLLCAALA-------------VSLARRS--SP FUGRU379_PE26 ISOFORMIN ------------------CRAGV-----VLLCAALA-------------VSLARRS--SP FUGRU379_PE27 ISOFORMIN ------------------------------------------------------------ GASACGROUPVIII_9_PE15 NOISO --------------VMSVRRAAL-----VLLCAGLA-------------LT-------SP GASACGROUPXVI_9_PE50 NOISO ---------------MFSRSL--TVCATLCLWITALTS--------GAGSASGRKQD--- GORGOX_9_PE8 NOISO ---------------MVPGVPGA--VLTLCLWLAASSG--CLA--AGPGAAAARRLD--- HSX_PE126 NOISO ---------------MVPGVPGA--VLTLCLWLAASSG--CLA--AGPGAAAARRLD--- LOXAF94_5_PE1 NOISO ------------------------------------------------------------ MACEUGS_202_PE1 NOISO ---------------------------TLFLWITASWG--CLAT-AAGLGAAARKQD--- MACMUX_7_PE3 ISOFORMIN ------------------------------------------------------------ MACMUX_7_PE4 ISOFORMIN ------------------------------------------------------------ MACMUX_7_PE5 ENSMMUG00000018191 ------------------------------------------------------------ MICMUGS_82_PE1 NOISO -----------------PGAPDT--HKTSWLLLAAPGG--WLA--AGPGAAAAR-RD--- MONDO7_36_PE1 ENSMODG00000017475 ---------------MVLKDPGV--FLTLFLWITASWG--CLAT-AAGLGAAARKQD--- MONDO7_36_PE2 ISOFORMIN ------------------------------------------------------------ MONDO7_36_PE3 ISOFORMIN ------------------------------------------------------------ ORNANULTRA462_5_PE4 NOISO ------------------------------------------------------------ ORYLA21_27_PE27 NOISO ---------------MFSRSL--KLCASLCLWITALTS---------PGSVSARKQD--- ORYLA4_17_PE19 NOISO ---------------MSVLRVGS-----VLLWAVLA-------------VSRARRS--PT OTOGAGS_100_PE1 NOISO ------------------------------------------------------------ PANTRX_9_PE5 NOISO ------------------------------------------------------------ PIGX_5_PE1 ENSSSCG00000012101 ------------------------------------------------------------ PIGX_5_PE2 ISOFORMIN ---------------MVPGASGA--ALTLCLWLAASGG--CLA--AGPGAGAARRLD--- POEGU1_21_PE3 NOISO ---------------MVRRAPGV--SLALLLWSDGAEG--RPAPDGPGAAAAARRQD--- PONPYX_9_PE1 NOISO ---------------MVPGVPGT--VLTLCLWLAASSG--CLA--AGPGAAAARRLD--- PTEVAGS_69_PE1 NOISO ---------------MVAGAPGA--ALTLCLWLADSGG--CLA--AGPGFAAARRLD--- SPETRGS_101_PE1 NOISO ------------------------------------------------------------ TARSYGS_145_PE1 NOISO ---------------MVPGVTGA--ALTLCLWLAASGG--CVA--ASPGAAAARRLE--- TETNG1_PE1229 NOISO -----------LLGVMSGRRAGL-----VLLCAALA-------------VSHARRS--SP TETNG2_PE925 ENSTNIG00000013951 ---------------MICGSA--STRLSLCLWITALMS---------AGSVCARKQD--- TETNG2_PE926 ISOFORMIN ---------------MICGSA--STRLSLCLWITALMS---------AGSVCARKQD--- TETNG3_PE442 ENSTNIG00000014485 -------------------ML--TAVLSASLWILVLSG---------PGGSAKRRPGDPD TETNG3_PE443 ISOFORMIN -------------------ML--TAVLSASLWILVLSG---------PGGSAKRRPGDPD TUPGBGS_89_PE1 NOISO ------------------------------------------------------------ TURTRGS_49_PE1 NOISO ------------------------------------------------------------ XENTR430_1_PE1 ISOFORMIN --------------------------------QTLMQKLCCCLLYLTGHVASSRKQD--- XENTR430_1_PE2 ENSXETG00000022299 ---------------MWLREPGCRSLLTFILWITLVW-GSRCAATATAAAASSRKQD--- XENTR430_1_PE3 ISOFORMIN -----------------------------------------------------RKQD--- MATCH CONSENSUS ??????????????????????????????L??????????????????????R??????

AILMEGL195124_1_PE1 NOISO ------------------------------------------------------------ ANOCA81_1_PE4 NOISO --------------------------------------------------CLEPCKESWD CALJAX_7_PE4 NOISO -ESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGD CANFAX_6_PE1 NOISO --------------------------------------------------CCEDCKVPGG CAVPO126_4_PE1 NOISO ------------------------------------------------------------ CHICK1_PE2112 NOISO --------------------------------------------------CLEPCKESWD DANRE1_32_PE20 NOISO -SSSALGSIFRTRCAARCLSLHSTRIALSPRHFQSNGSLGWCQSHKQCAKCLEPCKDSWE DANRE22_43_PE35 NOISO EEAESLEKMESARCVSRCLTLHITQITAAFRHLQNDRVLGWCENHRRCSQCLQPCKELWE DASNOGS_123_PE1 NOISO -ESLAAGSVQRARCASRCLSLQITRISAFFQHFQXXXXXXXXXXXXXXXXCLEPCKESWD FELCAGS_92_PE1 NOISO ----------------------------------NNGSLVWCQNHKQCSKCLEPCKDTWD FUGRU103_PE97 ENSTRUG00000009929 -ESFFTGSIYRARCASRCLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKESWD FUGRU103_PE98 ISOFORMIN -ESFFTGSIYRARCASRCLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKESWD FUGRU103_PE99 ISOFORMIN -ESFFTGSIYRARCASRCLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKESWD FUGRU284_PE18 ENSTRUG00000004145 AEESWSESVSRARCASRCLSLHSVAALSTPLQ--NNGSLGWCQTDKQCSKCLEPCKESRG FUGRU284_PE19 ISOFORMIN AEESWSESVSRARCASRCLSLHSVAALSTPLQ--NNGSLGWCQTDKQCSKCLEPCKESRG FUGRU284_PE20 ISOFORMIN AEESWSESVSRARCASRCLSLHSVAALSTPLQ--NNGSLGWCQTDKQCSKCLEPCKESRG FUGRU284_PE21 ISOFORMIN ------ESVSRARCASRCLSLHSVAALSTPLQ--NNGSLGWCQTDKQCSKCLEPCKESRG FUGRU379_PE22 ISOFORMIN EQEDVQEKIHSARCTSRCLTLHMTQLTAAFRHLQSDQVLDWCDSHRRCAQCLQPCKELWE FUGRU379_PE23 ISOFORMIN EQEDVQEKIHSARCTSRCLTLHMTQLTAAFRHLQSDQVLDWCDSHRRCAQCLQPCKELWE FUGRU379_PE24 ISOFORMIN EQEDVQEKIHSARCTSRCLTLHMTQLTAAFRHLQSDQVLDWCDSHRRCAQCLQPCKELWE FUGRU379_PE25 ENSTRUG00000006504 EQEDVQEKIHSARCTSRCLTLHMTQLTAAFRHLQSDQVLDWCDSHRRCAQCLQPCKELWE FUGRU379_PE26 ISOFORMIN EQEDVQEKIHSARCTSRCLTLHMTQLTAAFRHLQSDQVLDWCDSHRRCAQCLQPCKELWE FUGRU379_PE27 ISOFORMIN --------------------------------------------------CLQPCKELWE GASACGROUPVIII_9_PE15 NOISO EHEDVQE--NSARCTSRCLSLHVTQLRAAFKHLQSDQVLVWCENHRRCAQCLQPCKELLE GASACGROUPXVI_9_PE50 NOISO -ESFFTSSVYRARCASRCLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKETWD GORGOX_9_PE8 NOISO -ESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGD HSX_PE126 NOISO -ESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGD LOXAF94_5_PE1 NOISO ---------------------------------------------RQCPQCLEPCKESWD MACEUGS_202_PE1 NOISO -ETLSAVSIYRARCTSRCFSLQITRISAFFKHFQNNGSLVWCQTHKQCSKCLEPCKESWE MACMUX_7_PE3 ISOFORMIN ------------------------------------------------------------ MACMUX_7_PE4 ISOFORMIN ------------------------------------------------------------ MACMUX_7_PE5 ENSMMUG00000018191 ------------------------------------------------------------ MICMUGS_82_PE1 NOISO -ESLSAESVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKDSGD MONDO7_36_PE1 ENSMODG00000017475 -ETLSAVSVYRARCTSRCLSLQITRISAFFKHFQNNGSLVWCQTHKQCSKCLEPCKESWE MONDO7_36_PE2 ISOFORMIN ------------------------------------------------------------ MONDO7_36_PE3 ISOFORMIN ------------------------------------------------------------ ORNANULTRA462_5_PE4 NOISO --------------------------------------------------CLEPCKESWD ORYLA21_27_PE27 NOISO -DSFFTASIYRARCASRCLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKESWD ORYLA4_17_PE19 NOISO EPEEVQEHINSARCTSRCLSLHMTQITAAFRHIQSDEVLVWCENHRRCAQCLQPCEELWE OTOGAGS_100_PE1 NOISO --------------------------------------------------CLEPCKDSGD PANTRX_9_PE5 NOISO ----------------------------------NNGSLVWCQNHKQCSKCLEPCKESGD PIGX_5_PE1 ENSSSCG00000012101 ------------------------------------------------------------ PIGX_5_PE2 ISOFORMIN -ESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKASWD POEGU1_21_PE3 NOISO -EPF-----ATARCAFRCVSLQITRISAFFKHFQNNGSLAWCQNHKQCSKCLEPCKESWD PONPYX_9_PE1 NOISO -ESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGD PTEVAGS_69_PE1 NOISO -EALSARSVQRARCASRCLSLHITRMSAFFQRSQNNGSLVWCQNHKQCSKCLEPCKESWD SPETRGS_101_PE1 NOISO ----------------------------------NNGSLVWCQNHKQCSKXXXXXXXXXX TARSYGS_145_PE1 NOISO -ESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGD TETNG1_PE1229 NOISO EQEDVQEKIHSARCTSRCLTLHMTQLTAAFRHLQSDQVLDWCDSHRRCAQCLQPCKELWE TETNG2_PE925 ENSTNIG00000013951 -DSFFTGSIYRARCASRCLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKESWD TETNG2_PE926 ISOFORMIN -DSFFTGSIYRARCASRCLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKESWD TETNG3_PE442 ENSTNIG00000014485 SEESWSESVSRARCASRCLSLHSVGALSTPLQFVNNGSLGWCQADKQCSKCLEPCKESWG TETNG3_PE443 ISOFORMIN SEESWSESVSRARCASRCLSLHSVGALSTPLQ--NNGSLGWCQADKQCSKCLEPCKESWG TUPGBGS_89_PE1 NOISO ----------------------------------NNGSLVWCQSHKQCSKCLEPCKESGD TURTRGS_49_PE1 NOISO ----------------------------------NNGSLVWCQNHKQCSKCLEPCKVSWD XENTR430_1_PE1 ISOFORMIN -ESLSAQSIYRARCTSRCLSLHITRISAYFKHFQNNGSLIWCQNHKQCSKCTLMAVSSNT XENTR430_1_PE2 ENSXETG00000022299 -ESLSAQSIYRARCTSRCLSLHITRISAYFKHFQNNGSLIWCQNHKQCSKCTLMAVSSNT XENTR430_1_PE3 ISOFORMIN -ESLSAQSIYRARCTSRCLSLHITRISAYFKHFQNNGSLIWCQNHKQCSKCTLMAVSSNT MATCH CONSENSUS ???????????ARC?SRCLSL??T???A?F?H?QNNGSL?WCQ?HKQCSKCLEPCKESW?

AILMEGL195124_1_PE1 NOISO --------FSFQPLFPKKNHECLTSCEFLKYILSAKQGDCPAPEKASGFAAACVESCEAD ANOCA81_1_PE4 NOISO LKKNHCQ-SFCEPLFPKKNYECLTSCEFLKYIVSVKQGDCPAPEKASGFAAACVESCEAD CALJAX_7_PE4 NOISO LRKHQCQ-SFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD CANFAX_6_PE1 NOISO LQEKKANTFISEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEAD CAVPO126_4_PE1 NOISO ----ECG-SMCKPLFPKKNYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD CHICK1_PE2112 NOISO LKKNHCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEAD DANRE1_32_PE20 NOISO LKDGPCR-DLCEHAFPKRHGECVTSCEFLRSVMVVKQGDCPPPERASGFAAACVEGCEED DANRE22_43_PE35 NOISO TRRALSPKTCE-------HHECVTSAEFLRSLRVQKQGDCPPAQRASGFAAACVESCARD DASNOGS_123_PE1 NOISO LRKHQCR-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEVD FELCAGS_92_PE1 NOISO LQKEQC-HSLCEPLFPKKNYECLTSCEFLKYILAVKQGDCPAPEKASGFAAACVESCEAD FUGRU103_PE97 ENSTRUG00000009929 LKENQCQ-DLCEPLFPKKHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEED FUGRU103_PE98 ISOFORMIN LKENQCQ-DLCEPLFPKKHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEED FUGRU103_PE99 ISOFORMIN LKENQCQ-DLCEPLFPKKHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEED FUGRU284_PE18 ENSTRUG00000004145 MDRKTNCKDFCERAFSRKNWECVTSCEFLQSVLAVKQGTCPPPDRASGFAAACVESCDHD FUGRU284_PE19 ISOFORMIN MDRKTNCKDFCERAFSRKNWECVTSCEFLQSVLAVKQGTCPPPDRASGFAAACVESCDHD FUGRU284_PE20 ISOFORMIN MDRKTNCKDFCERAFSRKNWECVTSCEFLQSVLAVKQGTCPPPDRASGFAAACVESCDHD FUGRU284_PE21 ISOFORMIN MDRKTNCKDFCERAFSRKNWECVTSCEFLQSVLAVKQGTCPPPDRASGFAAACVESCDHD FUGRU379_PE22 ISOFORMIN TKRILSPKSCE------KQTECVTSREFLTSLRSSRQGDCPPPQRATGFAAACVESCSSD FUGRU379_PE23 ISOFORMIN TKRILSPKSCESYPLPQKQTECVTSREFLTSLRSSRQGDCPPPQRATGFAAACVESCSSD FUGRU379_PE24 ISOFORMIN TKRILSPKSCEKL-LPQKQTECVTSREFLTSLRSSRQGDCPPPQRATGFAAACVESCSSD FUGRU379_PE25 ENSTRUG00000006504 TKRILSPKSCE------KQTECVTSREFLTSLRSSRQGDCPPPQRATGFAAACVESCSSD FUGRU379_PE26 ISOFORMIN TKRILSPKSCEKL-LPQKQTECVTSREFLTSLRSSRQGDCPPPQRATGFAAACVESCSSD FUGRU379_PE27 ISOFORMIN TKRILSPKSCEKL-LPQKQTECVTSREFLTSLRSSRQGDCPPPQRATGFAAACVESCSSD GASACGROUPVIII_9_PE15 NOISO TRKVLSPKSCE------KQTECVTSREFLTSLRLSRQGDCPPPQRATGFAAACVESCSLD GASACGROUPXVI_9_PE50 NOISO LKENQCQ-DLCEPLFPKKHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEED GORGOX_9_PE8 NOISO LRKHQCQ-SFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD HSX_PE126 NOISO LRKHQCQ-SFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD LOXAF94_5_PE1 NOISO QRRHQCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPERASGFAAACVESCEVD MACEUGS_202_PE1 NOISO LKKNQCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEID MACMUX_7_PE3 ISOFORMIN --------------FPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD MACMUX_7_PE4 ISOFORMIN ------------PLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD MACMUX_7_PE5 ENSMMUG00000018191 -------------------YECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD MICMUGS_82_PE1 NOISO LRKQQCQ-SFCEPLFPKKNYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD MONDO7_36_PE1 ENSMODG00000017475 LKKNQCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEID MONDO7_36_PE2 ISOFORMIN ------------PLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEID MONDO7_36_PE3 ISOFORMIN --------------FPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEID ORNANULTRA462_5_PE4 NOISO LKKNQCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACLESCEAD ORYLA21_27_PE27 NOISO LKENQCQ-DLCEPLFPKKHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEED ORYLA4_17_PE19 NOISO TRTVLPPKACE------KQTECMTSREFLASLRSSRQGDCPPPQRATGFAAACVESCSSD OTOGAGS_100_PE1 NOISO LRKHQCQ-SFCEPLFPKKNYECLTSCEFLKYVLLVKQGDCPAPEKASGFAAACVESCEVD PANTRX_9_PE5 NOISO LRKHQCQ-SFCEPL-PKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD PIGX_5_PE1 ENSSSCG00000012101 -----------QPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEVD PIGX_5_PE2 ISOFORMIN LRNQQCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEVD POEGU1_21_PE3 NOISO LKKNHCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEAD PONPYX_9_PE1 NOISO LRKHQCQ-SFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVD PTEVAGS_69_PE1 NOISO LWKQQCQ-SFCEPLFPRKNSECLTSCEFLKYVLSVRQGDCPAPERASGFAAACVESCDVD SPETRGS_101_PE1 NOISO XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXAPERASGFAAACVESCDVD TARSYGS_145_PE1 NOISO LRKHQCQ-SFCEPLFPKKNYECLTSCEFLKYILLIKQGDCPAPEKASGFAAACVESCEVD TETNG1_PE1229 NOISO TKRILSPKSCEEHWLPQKQTECVTSREFLTSLRSSRQGDCPPPQRAAGFAAACVESCSSD TETNG2_PE925 ENSTNIG00000013951 LKENQCQ-DLCEPLFPKKHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEED TETNG2_PE926 ISOFORMIN LKENQCQ-DLCEPLFPKKHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEED TETNG3_PE442 ENSTNIG00000014485 MDRKINCNQFCERAFPRKNWECVTSCEFLQSALAVKQGTCLPPERASGFAAACVEGCDHD TETNG3_PE443 ISOFORMIN MDRKINCNQFCERAFPRKNWECVTSCEFLQSALAVKQGTCLPPERASGFAAACVEGCDHD TUPGBGS_89_PE1 NOISO LRKHQCQ-SFCEPLFPKKNYECLTSCEFLKYILLVKQGECPAPEKASGFAAACVESCEVD TURTRGS_49_PE1 NOISO LRKQQCQ-SFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEVD XENTR430_1_PE1 ISOFORMIN M----------------KHYECLTSCEFLKSVLSVKQGDCPAPEKASGFAAACVESCDAD XENTR430_1_PE2 ENSXETG00000022299 MKDKKCV-TYCEPLFPKKHYECLTSCEFLKSVLSVKQGDCPAPEKASGFAAACVESCDAD XENTR430_1_PE3 ISOFORMIN MKDKKCV-TYCEPLFPKKHYECLTSCEFLKSVLSVKQGDCPAPEKASGFAAACVESCDAD MATCH ..::*:******:*.* * CONSENSUS L????C??S?CEPLFPKK?YECLTSCEFLKY?L?VKQGDCPAPEKASGFAAACVESCE?D

AILMEGL195124_1_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLDVKWSSKFNISIEP ANOCA81_1_PE4 NOISO SECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELKFNELQSGQLEIKWSSKFNISIEP CALJAX_7_PE4 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGHLEVKWSSKFNISIEP CANFAX_6_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP CAVPO126_4_PE1 NOISO QECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELKSGQLEIKWSSKFNISIEP CHICK1_PE2112 NOISO SECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELKFIELQSGDLEVKWSSKFNISIEP DANRE1_32_PE20 NOISO GECSGQKKCCPNGCGHTCQSPKNLYRGAPLKPRKELVFEELESGVLEVRWSSKFNVSAEP DANRE22_43_PE35 NOISO RECSGVKKCCSNGCGHTCQSPANLFKGVPLKPRRDISFSEDHQGHVKVTWMSKFNVSVEP DASNOGS_123_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYK-VPLKPRKELRFTELQXXXXXXXXXXXXXXXXXX FELCAGS_92_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP FUGRU103_PE97 ENSTRUG00000009929 GECSAVKKCCSNGCGHTCQLPKNLYKGVPLKPRKELVFLEQASGQLEIRWSSKFNISVEP FUGRU103_PE98 ISOFORMIN GECSAVKKCCSNGCGHTCQLPKNLYKGVPLKPRKELVFLEQASGQLEIRWSSKFNISVEP FUGRU103_PE99 ISOFORMIN GECSAVKKCCSNGCGHTCQLPKNLYKGVPLKPRKELVFLEQASGQLEIRWSSKFNISVEP FUGRU284_PE18 ENSTRUG00000004145 QECSAQKKCCSNGCGHTCQAPKDLYKGVPLRPRKELSFKELPSGVLEVRWSSRFNISAEP FUGRU284_PE19 ISOFORMIN QECSAQKKCCSNGCGHTCQAPKDLYKGVPLRPRKELSFKELPSGVLEVRWSSRFNISAEP FUGRU284_PE20 ISOFORMIN QECSAQKKCCSNGCGHTCQAPKDLYKGVPLRPRKELSFKELPSGVLEVRWSSRFNISAEP FUGRU284_PE21 ISOFORMIN QECSAQKKCCSNGCGHTCQAPKDLYKGVPLRPRKELSFKELPSGVLEVRWSSRFNISAEP FUGRU379_PE22 ISOFORMIN QHCPSPRKCCSNGCGHTCQPPANLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEP FUGRU379_PE23 ISOFORMIN QHCPSPRKCCSNGCGHTCQPPANLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEP FUGRU379_PE24 ISOFORMIN QHCPSPRKCCSNGCGHTCQPPANLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEP FUGRU379_PE25 ENSTRUG00000006504 QHCPSPRKCCSNGCGHTCQPPANLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEP FUGRU379_PE26 ISOFORMIN QHCPSPRKCCSNGCGHTCQPPANLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEP FUGRU379_PE27 ISOFORMIN QHCPSPRKCCSNGCGHTCQPPANLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEP GASACGROUPVIII_9_PE15 NOISO KHCPSSRKCCPNGCGHTCQAPANLYKGVPLKPRREMSFGEDPEGRVKVVWVSKFNVTVEP GASACGROUPXVI_9_PE50 NOISO GECSAVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELGFVEQPSGQLEIRWSSKFNISVEP GORGOX_9_PE8 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP HSX_PE126 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP LOXAF94_5_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELSSGQLEIKWSSKFNISIEP MACEUGS_202_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKNLYKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MACMUX_7_PE3 ISOFORMIN NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP MACMUX_7_PE4 ISOFORMIN NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP MACMUX_7_PE5 ENSMMUG00000018191 NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP MICMUGS_82_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP MONDO7_36_PE1 ENSMODG00000017475 NECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP MONDO7_36_PE2 ISOFORMIN NECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP MONDO7_36_PE3 ISOFORMIN NECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP ORNANULTRA462_5_PE4 NOISO SECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP ORYLA21_27_PE27 NOISO GECSAVKKCCSNGCGHTCQLPKNLYKGVPLKPRKELVFLEHPSGQLEIHWSSKFNISVEP ORYLA4_17_PE19 NOISO QHCPSSRKCCFNGCGHTCQAPANLYKGVPLKPRREMSFTEDSEGHVKVGWVSKFNVSMEP OTOGAGS_100_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP PANTRX_9_PE5 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP PIGX_5_PE1 ENSSSCG00000012101 NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP PIGX_5_PE2 ISOFORMIN NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP POEGU1_21_PE3 NOISO IECSGVKKCCSNGCGHTCQIPKNLYKGVPLKPRKELKFIEHQSGDLEVKWSSKFNISIEP PONPYX_9_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEP PTEVAGS_69_PE1 NOISO SECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP SPETRGS_101_PE1 NOISO LECSGVKKCCSNGCGHTCQVPKTLYKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TARSYGS_145_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP TETNG1_PE1229 NOISO QHCPSPRKCCSNGCGHTCQAPSNLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEP TETNG2_PE925 ENSTNIG00000013951 SECSAVKKCCSNGCGHTCQLPKNLYKGVPLKPRKELVFLEQASGQLEIRWSSKFNISVEP TETNG2_PE926 ISOFORMIN SECSAVKKCCSNGCGHTCQLPKNLYKGVPLKPRKELVFLEQASGQLEIRWSSKFNISVEP TETNG3_PE442 ENSTNIG00000014485 RECSAQKKCCFNGCGHTCQAPKDLYKSVPLKPRKELSLRELPSGQLEVRWSSRFNISAEP TETNG3_PE443 ISOFORMIN RECSAQKKCCFNGCGHTCQAPKDLYKSVPLKPRKELSLRELPSGQLEVRWSSRFNISAEP TUPGBGS_89_PE1 NOISO NECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELHSGHLEIKWSSKFNVSIEP TURTRGS_49_PE1 NOISO SECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEIKWSSKFNISIEP XENTR430_1_PE1 ISOFORMIN NECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELTFDEPQPGHLDIKWSSKFNISVEP XENTR430_1_PE2 ENSXETG00000022299 NECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELTFDEPQPGHLDIKWSSKFNISVEP XENTR430_1_PE3 ISOFORMIN NECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELTFDEPQPGHLDIKWSSKFNISVEP MATCH .*.. :*** ******** * *:: CONSENSUS ?ECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKEL?F?ELQSGQLEVKWSSKFNIS?EP

AILMEGL195124_1_PE1 NOISO VIYVVQRRWNYGIHPSEDDATQWRTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR ANOCA81_1_PE4 NOISO VLYVVQRRWNYGIHPSEDDATSWQTVAQTTDERLQL-SD-IRPSRWYQFRVAAINVHGTR CALJAX_7_PE4 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPTRWYQFRVAAVNVHGTR CANFAX_6_PE1 NOISO VIYVVQRRWNYGIHPSEDDATQWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR CAVPO126_4_PE1 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR CHICK1_PE2112 NOISO VIYVVQRRWNQGIHPSEDDATNWQTVAQTTDERVQL-SD-IRASRWYQFRVAAVNVHGTR DANRE1_32_PE20 NOISO VLNVLQRRWNYGIHPSEDGATEWQVVARTSEERVWL-TD-IRPGRWYQFRVAAVNVHGTR DANRE22_43_PE35 NOISO VLYVLQRRWNHGIHPSEDEASAWQTVLMTMEDRSVL-KD-IRPHRWYQFRVSAVNSQGTR DASNOGS_123_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXTTDERLQL-TD-VRPSRWYQFRVAAVNVHGTR FELCAGS_92_PE1 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAGVNVHGTR FUGRU103_PE97 ENSTRUG00000009929 VLYVVQRRWNYGIHPSEDDATDWETVAQTAEERVQL-AD-IRASRWYQFRVAAVNVHGTR FUGRU103_PE98 ISOFORMIN VLYVVQRRWNYGIHPSEDDATDWETVAQTAEERVQL-AD-IRASRWYQFRVAAVNVHGTR FUGRU103_PE99 ISOFORMIN VLYVVQRRWNYGIHPSEDDATDWETVAQTAEERVQL-AD-IRASRWYQFRVAAVNVHGTR FUGRU284_PE18 ENSTRUG00000004145 VVYVLQRRWNFGIQPSEDTATSWRVVLQTTEEGARL-VD-IRPGRWYQFRVAATNTRGTR FUGRU284_PE19 ISOFORMIN VVYVLQRRWNFGIQPSEDTATSWRVVLQTTEEGARL-VD-IRPGRWYQFRVAATNTRGTR FUGRU284_PE20 ISOFORMIN VVYVLQRRWNFGIQPSEDTATSWRVVLQTTEEGARL-VD-IRPGRWYQFRVAATNTRGTR FUGRU284_PE21 ISOFORMIN VVYVLQRRWNFGIQPSEDTATSWRVVLQTTEEGARL-VD-IRPGRWYQFRVAATNTRGTR FUGRU379_PE22 ISOFORMIN VVYILQSRWNIGIHPSEDHASPWTTVAMTLSEDAVL-SE-LRPQRWYQFRVAAINSHGSR FUGRU379_PE23 ISOFORMIN VVYILQSRWNIGIHPSEDHASPWTTVAMTLSEDAVL-SE-LRPQRWYQFRVAAINSHGSR FUGRU379_PE24 ISOFORMIN VVYILQSRWNIGIHPSEDHASPWTTVAMTLSEDAVL-SE-LRPQRWYQFRVAAINSHGSR FUGRU379_PE25 ENSTRUG00000006504 VVYILQSRWNIGIHPSEDHASPWTTVAMTLSEDAVL-SE-LRPQRWYQFRVAAINSHGSR FUGRU379_PE26 ISOFORMIN VVYILQSRWNIGIHPSEDHASPWTTVAMTLSEDAVL-SE-LRPQRWYQFRVAAINSHGSR FUGRU379_PE27 ISOFORMIN VVYILQSRWNIGIHPSEDHASPWTTVAMTLSEDAVL-SE-LRPQRWYQFRVAAINSHGSR GASACGROUPVIII_9_PE15 NOISO VVYMLQSRWNAGIHPSEDHASPWTTVAMTLSEDVVL-LD-LRPHRWYQFRVAAINSHGSR GASACGROUPXVI_9_PE50 NOISO VLYVVQRRWNYGIHPSEDDATEWQTVAQTAEERVQL-AD-VRASRWYQFRVAAVNVHGTR GORGOX_9_PE8 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR HSX_PE126 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR LOXAF94_5_PE1 NOISO VIYVLQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-AD-IRPSRWYQFRVAAVNVHGTR MACEUGS_202_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXTTDERVQ-LSD-IRPSRWYQFRVAAVNVHGTR MACMUX_7_PE3 ISOFORMIN VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR MACMUX_7_PE4 ISOFORMIN VIYVVQRRWNYGIHPSEDDATHWQTVAQRFLNSGLG-YN-LLPE-------IASGLHKTQ MACMUX_7_PE5 ENSMMUG00000018191 VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR MICMUGS_82_PE1 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-MD-IRPSRWYQFRVAAVNVHGTR MONDO7_36_PE1 ENSMODG00000017475 VIYVVQRRWNYGIHPSEDDATNWQTVAQTTDERVQ-LSDIR-PSRWYQFRVAAVNVHGTR MONDO7_36_PE2 ISOFORMIN VIYVVQRRWNYGIHPSEDDATNWQTVAQQVFTCMFDMFTLHQGNQRYVVP-----VPSGC MONDO7_36_PE3 ISOFORMIN VIYVVQRRWNYGIHPSEDDATNWQTVAQTTDERVQ-LSDIR-PSRWYQFRVAAVNVHGTR ORNANULTRA462_5_PE4 NOISO VIYVVQRRWNYGIHPSEDDATSWQTVAQTTDERVQ-LSD-IRPSRWYQFRVAAVNVHGTR ORYLA21_27_PE27 NOISO VLYVVQRRWNYGIHPSEDDATEWQTVAQTAEERIQL-AD-TRASRWYQFRVAAVNVHGTR ORYLA4_17_PE19 NOISO VVYLLESRWNIGIHPSEDHASPWSAVAMTLSEEVLL-TD-LRPQRWYQFRVAAVNSQGSR OTOGAGS_100_PE1 NOISO VIYVVQRRWNYGIHPSEDDATPWQTVAQTTDERVQL-MD-IRPSRWYQFRVAAVNVHGTR PANTRX_9_PE5 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR PIGX_5_PE1 ENSSSCG00000012101 VIYVVQRRWNYGIHPSEDDATPWQTIAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR PIGX_5_PE2 ISOFORMIN VIYVVQRRWNYGIHPSEDDATPWQTIAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR POEGU1_21_PE3 NOISO VIYVVQRRWNQGIHPSEDDATNWQTVAQTTDERVRL-PD-IRASRWYQFRVAAVNVHGTR PONPYX_9_PE1 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR PTEVAGS_69_PE1 NOISO VIYVVQRRWNPGIHPSEDDATHWQTVAQTTDERVQL-MD-IRPSRWYQFRVAAVNVHGTR SPETRGS_101_PE1 NOISO XXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX-XX-XXXX--X---XXXXXXXXXX TARSYGS_145_PE1 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR TETNG1_PE1229 NOISO VVYILQSRWNIGIHPSEDHASPWTTVAMVLSEDVVL-SD-LRPQRWYQFRVAAINSHGSR TETNG2_PE925 ENSTNIG00000013951 VLYVVQRRWNYGIHPSEDEATDWETVAQTAEERVQL-VD-IRASRWYQFRVAAVNVHGTR TETNG2_PE926 ISOFORMIN VLYVVQRRWNYGIHPSEDEATDWETVAQTAEERVQL-VD-IRASRWYQFRVAAVNVHGTR TETNG3_PE442 ENSTNIG00000014485 VVYVLQRRWNFGIQPSEDSATSWQVVAQTTEQGARL-SD-IRPGRWYQFRVAATNTRGTR TETNG3_PE443 ISOFORMIN VVYVLQRRWNFGIQPSEDSATSWQVVAQTTEQGARL-SD-IRPGRWYQFRVAATNTRGTR TUPGBGS_89_PE1 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQXXXXXXXX-XX-XXXXXXXXXXXXXXXXX--- TURTRGS_49_PE1 NOISO VIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQL-TD-IRPSRWYQFRVAAVNVHGTR XENTR430_1_PE1 ISOFORMIN VIYVVQRRWNYGIHPSEDDASNWQTMAQITDERVQL-SD-IRPSRWYQFRVAAVNVHGTR XENTR430_1_PE2 ENSXETG00000022299 VIYVVQRRWNYGIHPSEDDASNWQTMAQITDERVQL-SD-IRPSRWYQFRVAAVNVHGTR XENTR430_1_PE3 ISOFORMIN VIYVVQRRWNYGIHPSEDDASNWQTMAQITDERVQL-SD-IRPSRWYQFRVAAVNVHGTR MATCH CONSENSUS VIYVVQRRWNYGIHPSEDDAT?WQTVAQTTDERVQL??D?IRPSRWYQFRVAAVNVHGTR

AILMEGL195124_1_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANATV----------------NSD ANOCA81_1_PE4 NOISO GFTAPSKHF-----RSS---KDPSAPPAPSN--LRISNSTN----------------NSD CALJAX_7_PE4 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANST--I--------------NSD CANFAX_6_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANSTV----------------NSD CAVPO126_4_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANST--I--------------NSD CHICK1_PE2112 NOISO GFTAPSKHF-----RSS---KDPSAPPAPSN--IRIANISA----------------NND DANRE1_32_PE20 NOISO GYTTPSRHF-----RSS---KDPPPPPAPSD--LHVSDMTF----------------GAD DANRE22_43_PE35 NOISO GFTTPSKHF-----FSV---RDPLPPETPQN--ARTANQTLHP----------------D DASNOGS_123_PE1 NOISO GFTAPSKHF-----RSS---RDPSAPPAPAN--LRLTNSTA----------------NSD FELCAGS_92_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANSTV----------------NSD FUGRU103_PE97 ENSTRUG00000009929 GFTAPSKHF-----RSS---RDPAAPPRPSN--LRITSVTP----------------GDE FUGRU103_PE98 ISOFORMIN GFTAPSKHF-----RSS---RDPAAPPRPSN--LRITSVTP----------------GDE FUGRU103_PE99 ISOFORMIN GFTAPSKHF-----RSS---RDPAAPPRPSN--LRITSVTP----------------GDE FUGRU284_PE18 ENSTRUG00000004145 GFTTPSRHI-----HAS---RDPSNPPPPTE--LRVANMSF----------------GPG FUGRU284_PE19 ISOFORMIN GFTTPSRHI-----HAS---RDPSNPPPPTE--LRVANMSF----------------GPG FUGRU284_PE20 ISOFORMIN GFTTPSRHI-----HAS---RDPSNPPPPTE--LRVANMSF----------------GPG FUGRU284_PE21 ISOFORMIN GFTTPSRHI-----HAS---RDPSNPPPPTE--LRVANMSF----------------GPG FUGRU379_PE22 ISOFORMIN GFTTPSKHY-----MSS---KDPSPPEPPVN--VRVSNQTLEWS------------RGSG FUGRU379_PE23 ISOFORMIN GFTTPSKHY-----MSS---KDPSPPEPPVN--VRVSNQS----------------RGSG FUGRU379_PE24 ISOFORMIN GFTTPSKHY-----MSS---KDPSPPEPPVN--VRVSNQS----------------RGSG FUGRU379_PE25 ENSTRUG00000006504 GFTTPSKHY-----MSS---KDPSPPEPPVN--VRVSNQTLEWTGSQPGTQLVERSRGSG FUGRU379_PE26 ISOFORMIN GFTTPSKHY-----MSS---KDPSPPEPPVN--VRVSNQTLEWS------------RGSG FUGRU379_PE27 ISOFORMIN GFTTPSKHY-----MSS---KDPSPPEPPVN--VRVSNQTLEWS------------RGSG GASACGROUPVIII_9_PE15 NOISO GFTTPSKHY-----IST---KDPSPPEPPIN--VRVSNQTLES-------------GGSG GASACGROUPXVI_9_PE50 NOISO GFTAPSKHF-----RSS---RDPSAPPRPAG--LRVSNVTL----------------GDE GORGOX_9_PE8 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANST--V--------------NSD HSX_PE126 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANST--V--------------NSD LOXAF94_5_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANST--I--------------HSD MACEUGS_202_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPQAPAN--LRIANSTT----------------NSD MACMUX_7_PE3 ISOFORMIN GFTAPSKHF-----RSS---KDPGPSFLLSDPHFRILTSGSWV----------SHPGLSS MACMUX_7_PE4 ISOFORMIN PMVPVSSGCCECAWNSRLHCPQQTLPFFQSPRVMRVLTEIS---------------PNVE MACMUX_7_PE5 ENSMMUG00000018191 GFTAPSKHF-----RSS---KGNTSIPKETT--MNISANK--K--------------L-R MICMUGS_82_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANST--V--------------NGD MONDO7_36_PE1 ENSMODG00000017475 GFTAPSKHF-----RSS---KDPSAPPAPAN--LRIANSTT----------------NSD MONDO7_36_PE2 ISOFORMIN QKCIESISF-----ILV---ILPQIQQAPAN--LRIANSTT----------------NSD MONDO7_36_PE3 ISOFORMIN GFTAPSKHF-----RSS---KDPSAPPAPAN--LRIANSTT----------------NSD ORNANULTRA462_5_PE4 NOISO GFTAPSKHF-----RSS-KAADPSAPPAPSN--LRLANYTA----------------NSD ORYLA21_27_PE27 NOISO GFTAPSKHF-----RSS---RDPAAPPSAAN--LHVTNMSL----------------ADD ORYLA4_17_PE19 NOISO GFTTPSKHY-----ISS---KDPSPPEPPMN--IRVSNQTLNWAGLQLMPKVTERSSESG OTOGAGS_100_PE1 NOISO GFTAPSKHF-----RSS---KXXXXXXXXXX--XXXXXXX--X--------------XXX PANTRX_9_PE5 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANST--V--------------NSD PIGX_5_PE1 ENSSSCG00000012101 GFTAPSKHF-----RSS---KDPAAPPAPAN--LRLANSTV----------------NSD PIGX_5_PE2 ISOFORMIN GFTAPSKHF-----RSS---KDPAAPPAPAN--LRLANST--V--------------NSD POEGU1_21_PE3 NOISO GFTAPSKHF-----RSS---RDPSAPPAPSN--IRIANISA----------------NND PONPYX_9_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LQLANST--V--------------NSD PTEVAGS_69_PE1 NOISO GFTAPSKHF-----HSS---KDPSAPPAPAN--LRLANST--I--------------NGD SPETRGS_101_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXPSAPPAPAT----LANSTV----------------NSD TARSYGS_145_PE1 NOISO GFTAPSKHF-----RSS---KXXXXXXXXXX--XXXXXXX--X--------------XXX TETNG1_PE1229 NOISO GFTTPSKHY-----MSS---KDPSAPEPPVN--VRVSNQS----------------RGSG TETNG2_PE925 ENSTNIG00000013951 GFTAPSKHF-----RSS---RDPAAPPRPSS--LRITRLTP----------------GEE TETNG2_PE926 ISOFORMIN GFTAPSKHF-----RSS---RDPAAPPRPSS--LRITRLTP----------------GEE TETNG3_PE442 ENSTNIG00000014485 GFTTPSRHI-----HAS---RDPANPPAPAE--LRVANLSF----------------GPG TETNG3_PE443 ISOFORMIN GFTTPSRHI-----HAS---RDPANPPAPAE--LRVANLSF----------------GPG TUPGBGS_89_PE1 NOISO -----XXXXXXXXXXXXXXXXXPSAPPAPVN--LRLANSTV----------------HSD TURTRGS_49_PE1 NOISO GFTAPSKHF-----RSS---KDPSAPPAPAN--LRLANSTI----------------NSD XENTR430_1_PE1 ISOFORMIN GFTAPSKHF-----RSS---KDPSPPPAPTN--LRISNLTT----------------NNE XENTR430_1_PE2 ENSXETG00000022299 GFTAPSKHF-----RSS---KDPSPPPAPTN--LRISNLTT----------------NNE XENTR430_1_PE3 ISOFORMIN GFTAPSKHF-----RSS---KDPSPPPAPTN--LRISNLTT----------------NNE MATCH CONSENSUS GFTAPSKHF?????RSS???KDPSAPPAP?N??LR?AN?T??????????????????SD

AILMEGL195124_1_PE1 NOISO NTVTVAVVWDRPEEPDIP-VHHYKVFWSWTVSSKSLVPT-----------KKKRRKTTD- ANOCA81_1_PE4 NOISO GSVNIRIIWDLPEEPDIP-VHHYKVFWSWTVNSKSLVPS-----------KKKRRKTTD- CALJAX_7_PE4 NOISO GSVTVTIVWDLLEEPDIP-VHHYKVFWSWTVSSKSLVPT-----------KKKRRKTTD- CANFAX_6_PE1 NOISO NTVTVAIVWDLPEEPDIP-VHHYKVFWSWTVNSKSLVPT-----------KKKRRKTTD- CAVPO126_4_PE1 NOISO GSVTVTIVWDFPKEPDIP-VHHYKVFWSWPVSSKSLVPTK---------KKRRKTTDGV- CHICK1_PE2112 NOISO GTVNVMITWDLPEEPDIP-VHHYKVFWSWTYS-KYVIPA-----------KKKRRKITD- DANRE1_32_PE20 NOISO HSASVRLSWSISADLDIP-VNHYKLSWSSS---DHTLPP-----------KLKKRETVN- DANRE22_43_PE35 NOISO GTVSVLVLWETPRESDLV-VHHHKVTWSPRGTPS-------------------------- DASNOGS_123_PE1 NOISO GSVTVTLAWDAAGEPDVP-VHHYKVFWSWTVGSKSLVPT-----------KKKRRKTTD- FELCAGS_92_PE1 NOISO GTVTVAIVWDLPEEPDIP-VHHYKVFWSWTVSTKSLVPT-----------KKKRRKTTD- FUGRU103_PE97 ENSTRUG00000009929 GSVTARLNWTLPEEPDIP-IHHYKVFWSWTVPTKSMVPS-----------KKKRRKTTN- FUGRU103_PE98 ISOFORMIN GSVTARLNWTLPEEPDIP-IHHYKVFWSWTVPTKSMVPS-----------KKKRRKTTN- FUGRU103_PE99 ISOFORMIN GSVTARLNWTLPEEPDIP-IHHYKVFWSWTVPTKSMVPS-----------KKKRRKTTNG FUGRU284_PE18 ENSTRUG00000004145 RVVSARLQWSMPADLDVP-VHHYKVSWSWSHAGQFAASS-----------VNKRRKTVQ- FUGRU284_PE19 ISOFORMIN RVVSARLQWSMPADLDVP-VHHYKVSWSWSHAGQFAASS-----------VNKRRKTVQ- FUGRU284_PE20 ISOFORMIN RVVSARLQWSMPADLDVP-VHHYKVSWSWSHAGQFAASS-----------VNKRRKTVQ- FUGRU284_PE21 ISOFORMIN RVVSARLQWSMPADLDVP-VHHYKVSWSWSHAGQFAASS-----------VNKRRKTVQ- FUGRU379_PE22 ISOFORMIN VTVAVLLTWEPPREGDLP-VRNYRVTWMDRNTHT-------------------------- FUGRU379_PE23 ISOFORMIN VTVAVLLTWEPPREGDLP-VRNYRVTWMDRNTHTTHKHTHTLHAHT---HSNMHTLPTHS FUGRU379_PE24 ISOFORMIN VTVAVLLTWEPPREGDLP-VRNYRVTWMDRNTHTTHKHTHTLHAHT---HS--------- FUGRU379_PE25 ENSTRUG00000006504 VTVAVLLTWEPPREGDLP-VRNYRVTWMDRNTHTTHKHTHTLHAHT---HSNMHTLPTHS FUGRU379_PE26 ISOFORMIN VTVAVLLTWEPPREGDLP-VRNYRVTWMKWDLSIVKS----------------------- FUGRU379_PE27 ISOFORMIN VTVAVLLTWEPPREGDLP-VRNYRVTWMVSLKEMGL------------------------ GASACGROUPVIII_9_PE15 NOISO VTVAVFLSWEPPREGDLP-VHNYRITWMSQQ----------------------------- GASACGROUPXVI_9_PE50 NOISO GLVTARLNWTLPEEPDIP-IHHYKVFWSWTVPTKSLVPS-----------KKKRRKTTN- GORGOX_9_PE8 NOISO GSVTVTIVWDLPEEPDIP-VHHYKVFWSWMVSSKSLVPT-----------KKKRRKTTD- HSX_PE126 NOISO GSVTVTIVWDLPEEPDIP-VHHYKVFWSWMVSSKSLVPT-----------KKKRRKTTD- LOXAF94_5_PE1 NOISO GSVTATIVWDVPEDPDIP-VHHYKVFWSWTVSSKALVPT-----------KKKRRKTTE- MACEUGS_202_PE1 NOISO GSVTVRIIWDMPEEPDIP-VHHYKVFWSWTVNSKSVVPS-----------KKKRRKTTD- MACMUX_7_PE3 ISOFORMIN GHISIT-------LDVIP-CMHYRVSDNC----EDYKEGV---------GIKQKEKAGN- MACMUX_7_PE4 ISOFORMIN KRLTGKRNTSIPKEIKVD-LIHFEFFSSFAKGTLPQLPS-----------LERKKKETW- MACMUX_7_PE5 ENSMMUG00000018191 PNSTYLFLWKTEKEADSI-VFTAYKYHTGCYSMHALQSVS---------KTTADITDGN- MICMUGS_82_PE1 NOISO GSVTVTVVWDAPEEPDIP-VHHYKVFWSWTVSSKSLVPT-----------KKKRRKTTD- MONDO7_36_PE1 ENSMODG00000017475 GSVTVRIIWDMPEEPDIP-VHHYKVFWSWTVSSKSVVPS-----------KKKRRKTTD- MONDO7_36_PE2 ISOFORMIN GSVTVRIIWDMPEEPDIP-VHHYKVFWSWTVSSKSVVPS-----------KKKRRKTTD- MONDO7_36_PE3 ISOFORMIN GSVTVRIIWDMPEEPDIP-VHHYKVFWSWTVSSKSVVPS-----------KKKRRKTTD- ORNANULTRA462_5_PE4 NOISO GSVTVRIVWDMPEEPDIP-VHHYKVFWSWTVSSKSMVPS-----------KKKRRKTTE- ORYLA21_27_PE27 NOISO GLVTARLNWTLPHEPDIP-IHHYKVFWSWTVPTKSMVPS-----------KKKQRKTIN- ORYLA4_17_PE19 NOISO TTVAVLLNWEPPSEGDLL-IRNYRITWMPLHVHTAHKHTHSLQANAQRLHKNKQKWPTNS OTOGAGS_100_PE1 NOISO XXXXXXXXXXXXXX--XX-XXXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXX- PANTRX_9_PE5 NOISO GSVTVTIVWDLPEEPDIP-VHHYKVFWSWMVSSKSLVPT-----------KKKRRKTTD- PIGX_5_PE1 ENSSSCG00000012101 GSVSVTMVWDLPEEPDIP-VHHYKVFWSWTVSSKSLVPT-----------KKKRRKTTE- PIGX_5_PE2 ISOFORMIN GSVSVTMVWDLPEEPDIP-VHHYKVFWSWTVSSKSLVPT-----------KKKRRKTTE- POEGU1_21_PE3 NOISO GSVNALITWDLPEEPDIP-VHHYKVFWSWTYS-KYVIPA-----------KKKRRKITD- PONPYX_9_PE1 NOISO GSVTVTIVWDLPEEPDIP-VHHYKVFWSWTVSSKSLVPT-----------KKKRRKTTD- PTEVAGS_69_PE1 NOISO GSVTVTLVWDTPEEPDIP-LHHYKVFWSWTVNGKSLVPT-----------KKKRRKTAD- SPETRGS_101_PE1 NOISO GTVTVTIAWDLPEEPDIP-VHHYKVFWSWTVSNKSLVPT-----------KKKRRKTTD- TARSYGS_145_PE1 NOISO XXXXXXXXXXX---XXXX-XXXXXXXXXXXXXXXXXXXXX---------XXXXXRRTTD- TETNG1_PE1229 NOISO VTVAVLLSWEPPREGDLP-VRNYRVTWNPPHSRP-------------------------- TETNG2_PE925 ENSTNIG00000013951 GSVTARLNWTLPEEPDIP-IHHYKVFWSWTVPTRSMVPS-----------KKKRRKTTK- TETNG2_PE926 ISOFORMIN GSVTARLNWTLPEEPDIP-IHHYKVFWSWTVPTRSMVPS-----------KKKRRKTTK- TETNG3_PE442 ENSTNIG00000014485 RVVSARLQWTMPPDLDVP-VHHYKVSWSWSHSGQFAASP-----------LNKKRKIVQ- TETNG3_PE443 ISOFORMIN RVVSARLQWTMPPDLDVP-VHHYKVSWSWSHSGQFAASP-----------LNKKRKIVQ- TUPGBGS_89_PE1 NOISO GTVTVTLVWDLPEEPDLTRVHHYKAFWSWTVSSKSLVPT-----------KKKRRKTTD- TURTRGS_49_PE1 NOISO GSVTVTIVWDLPEEPDIP-VHHYKVFWSWTVSGKSLVPTK---------KKRRKTTGGX- XENTR430_1_PE1 ISOFORMIN GTVSVRITWDLPEEPDIP-VHHYKVFWSWTANRKSVVPA-----------KKKRRKTTE- XENTR430_1_PE2 ENSXETG00000022299 GTVSVRITWDLPEEPDIP-VHHYKVFWSWTANRKSVVPA-----------KKKRRKTTE- XENTR430_1_PE3 ISOFORMIN GTVSVRITWDLPEEPDIP-VHHYKVFWSWTANRKSVVPA-----------KKKRRKTTE- MATCH CONSENSUS G?VTV???WD?PEEPDIP?VHHYKVFWSWTV??KS?VP????????????KKKRRKTT??

AILMEGL195124_1_PE1 NOISO ----------------GSQNSVLLDRLQPDYSYTVELQAIAYWGQTRLKGAKASLHFTPS ANOCA81_1_PE4 NOISO ----------------GSQNYVILEGLQPNSIYMVELQAVTYWGQIRLKSAKVSLSFSST CALJAX_7_PE4 NOISO ----------------GFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST CANFAX_6_PE1 NOISO ----------------GSQNSVILDRLQPDSSYTVELQAVAYWGQTRLKGAKASLHFTPA CAVPO126_4_PE1 NOISO ----------------TLQISGILEEYSKDCGYLLQAKAGNWRGPCSVHDQKVSTVSLPG CHICK1_PE2112 NOISO ----------------GPQNYVVLEGLQPNSNYNVELQAVTRWGQIRLKSAKVSLHFSTA DANRE1_32_PE20 NOISO ----------------GDSTYAELDDLRENGSYTVELQAVSYWGQVPLKSSKAILQFTTS DANRE22_43_PE35 NOISO -----SSQSRAGRVTDGDVTQMELQGLQPNTPYTAQIQAISYWGQNRLKSSRAHISFTTT DASNOGS_123_PE1 NOISO ----------------GSQNSVVLERLQPDSSYMVELQAIAYWGQTRLKSAKVSLHFTSR FELCAGS_92_PE1 NOISO ----------------GSQNSVILDRLQPDSGYTVELQAIAYWGQTRLKGAKASLHFTPA FUGRU103_PE97 ENSTRUG00000009929 ----------------GAQSWVDLEGLQQNSSYSVELQAVTYWGQVRLKSSKASLQFSTA FUGRU103_PE98 ISOFORMIN ----------------GAQSWVDLEGLQQNSSYSVELQAVTYWGQVRLKSSKASLQFSTA FUGRU103_PE99 ISOFORMIN --HSSPMKNKSRRLISGAQSWVDLEGLQQNSSYSVELQAVTYWGQVRLKSSKASLQFSTA FUGRU284_PE18 ENSTRUG00000004145 ----------------Q--NHVDLDNMRSDRTYSVEVQAVSFWGQTPLKGPRAIIHFSTQ FUGRU284_PE19 ISOFORMIN ----------------Q--NHVDLDNMRSDRTYSVEVQAVSFWGQTPLKGPRAIIHFSTQ FUGRU284_PE20 ISOFORMIN ----------------QDWNHVDLDNMRSDRTYSVEVQAVSFWGQTPLKGPRAIIHFSTQ FUGRU284_PE21 ISOFORMIN ----------------Q--NHVDLDNMRSDRTYSVEVQAVSFWGQTPLKGPRAIIHFSTQ FUGRU379_PE22 ISOFORMIN -----GKRESNARVTQGAQCELWLHGLLPAASYLLSVQTVAYWGQKRLKSPKLQIVFTTI FUGRU379_PE23 ISOFORMIN RPVDQ-------------------------------VQTVAYWGQKRLKSPKLQIVFTTI FUGRU379_PE24 ISOFORMIN -------------ITEQAQCELWLHGLLPAASYLLSVQTVAYWGQKRLKSPKLQIVFTTI FUGRU379_PE25 ENSTRUG00000006504 RPVDQGKRESNARVTQGAQCELWLHGLLPAASYLLSVQTVAYWGQKRLKSPKLQIVFTTI FUGRU379_PE26 ISOFORMIN -------KKNNLKEHNRAQCELWLHGLLPAASYLLSVQTVAYWGQKRLKSPKLQIVFTTI FUGRU379_PE27 ISOFORMIN --VNCQVKEEQLKRTQQAQCELWLHGLLPAASYLLSVQTVAYWGQKRLKSPKLQIVFTTI GASACGROUPVIII_9_PE15 NOISO -----SKKESSSRITQGAQCELWLLGLLPATSYFLSVQTVAYWGQMRLKSHRAQIVFTTM GASACGROUPXVI_9_PE50 NOISO ----------------GAQSWVELEGLQQNSSYTVELQAVTYWGQVRLKSSKASLHFSTS GORGOX_9_PE8 NOISO ----------------GFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST HSX_PE126 NOISO ----------------GFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST LOXAF94_5_PE1 NOISO ----------------GSHNSVTLERLQPDSSYMVEVQAISYWGQMRLKSAKVSLHFTSS MACEUGS_202_PE1 NOISO ----------------GSQNYVILESLQPNNNYMVEIQAITYWGQVRLKSAKVSFYFTTT MACMUX_7_PE3 ISOFORMIN ----------------DFQNSVTLEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST MACMUX_7_PE4 ISOFORMIN ----------------KFQNSVTLEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST MACMUX_7_PE5 ENSMMUG00000018191 ----------------KFQNSVTLEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST MICMUGS_82_PE1 NOISO ----------------GFQNSVTLEKLQPDCDYVVELQAIAYXXXXXXXXXXXXXXXXXX MONDO7_36_PE1 ENSMODG00000017475 ----------------GSQNYVILEGLQPNNNYMVEIQAITYWGQVRLKSSKVSLYFTAT MONDO7_36_PE2 ISOFORMIN ----------------GSQNYVILEGLQPNNNYMVEIQAITYWGQVRLKSSKVSLYFTAT MONDO7_36_PE3 ISOFORMIN ----------------G--NYVILEGLQPNNNYMVEIQAITYWGQVRLKSSKVSLYFTAT ORNANULTRA462_5_PE4 NOISO ----------------GSQNYVVLEGLQANSNYMVELQAITYWGQVRLKSAKVSLYFTAT ORYLA21_27_PE27 NOISO ----------------GAQNWLDLEGLQQNSSYSVELQAITYWGQVRLKSPKSSLHFTTN ORYLA4_17_PE19 NOISO HRQEQKKKESNTVLTAGAQNELWVQGLLPGTPYSLSVQSVAYWGQKRLKSHRAQLVFTTI OTOGAGS_100_PE1 NOISO ----------------XFQNSVILEKLQPDCDYFVELQAIAYWGQTRLKSAKVSLHFTST PANTRX_9_PE5 NOISO ----------------GFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST PIGX_5_PE1 ENSSSCG00000012101 ----------------GSQNSVTLERLLPNCEYTVELQAIAYWGQTRLKSAKVSLQFTST PIGX_5_PE2 ISOFORMIN ----------------GSQNSVTLERLLPNCEYTVELQAIAYWGQTRLKSAKVSLQFTST POEGU1_21_PE3 NOISO ----------------GAQNYVVLEGLQPNSNYNVELQAVTRWGQIRLKSAKVSLHFSTT PONPYX_9_PE1 NOISO ----------------GFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST PTEVAGS_69_PE1 NOISO ----------------GAHNSVTLERLQPDGDYSVELQAVAYWGQTRLKSAKVSLRFSCT SPETRGS_101_PE1 NOISO ----------------GLQNFVVLERLQPDYDYTVELQAITYWGQTRLKSAKVSLR