Alignment of the gene Family HOG000113459 of HOGENOM

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Isoforms are ON
CALJAACFV01184156_1_PE1 ISOFORMIN --------------------PQSPPEGPDQ-SPLQSPVSAFISSTSLSPQSPPES----- CALJAACFV01184156_1_PE2 ENSCJAG00000034873 ADKEMPAAGMPSLLQSSPENPQSPPEGPDQ-SPLQSPVSAFISSTSLSPQSPPES----- HSX_PE2515 ENSG00000155495 GDKDMPTAGMPSLLQSSSESPQSCPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEGE PANTRX_142_PE2 NOISO GDKDMPTAGMPSLLQSSSESPQSCPEGEDSQSPLQIPQSSPESDDTMYPLQSSQSRSEGE PONPYXRD_9_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????PQS?PEG?D??SPLQ?P?S???S?????P?????S?????

CALJAACFV01184156_1_PE1 ISOFORMIN -----PQSPPEGP-VQSPLLSP------------------------------YPQSPPEG CALJAACFV01184156_1_PE2 ENSCJAG00000034873 -----PQSPPEGP-VQSPLLSPVSSSS--------------TSLSLPLSSPEYPQSPPEG HSX_PE2515 ENSG00000155495 DSSDPLQRPPEGKDSQSPLQIPQSSPEGDDTQSPLQNSQSSPEGKDSLSPLEISQSPPEG PANTRX_142_PE2 NOISO DSSDPLQRLPEGKDSQSPLQIPQSSPESDDTLYPLQNSQSSPEGKDSLSPLEISQSPPEG PONPYXRD_9_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ??????Q??PEG???QSPL??P????????????????????????????????QSPPEG

CALJAACFV01184156_1_PE1 ISOFORMIN -PAQSPLQSPVSTFISSTSLSPQSTPESPQSPPEGPVH-------------------SPE CALJAACFV01184156_1_PE2 ENSCJAG00000034873 -PAQSPLQSPVSTFISSTSLSPQSTPESPQSPPEGPVQSPLLSPVSSSSTSLSLPLSSPE HSX_PE2515 ENSG00000155495 EDVQSPLQNPASSFFSSALLS--------------------------------IFQSSPE PANTRX_142_PE2 NOISO EDVQSPLQNPASSFFSSALLS--------------------------------IFQSSPE PONPYXRD_9_PE1 NOISO ---QSPLQIPVSASFSST--------------------------------LLSIFQSSPD MATCH ***** *.*: :**: **: CONSENSUS ???QSPLQ?P?S?F?SS??LS???????????????????????????????????SSPE

CALJAACFV01184156_1_PE1 ISOFORMIN YPQSPPEGPAQSPLQSP------------------------------------------- CALJAACFV01184156_1_PE2 ENSCJAG00000034873 YPQSPPEGPAQSPLQSPVSTFVSSTSL-SPQSTPESPQSPPEGPAQSPLLSPVSSSSTSL HSX_PE2515 ENSG00000155495 STQSPFEGFPQSVLQIPVSAASSSTLVSIFQSSPESTQSPFEGFPQSPLQIPVSRSFSST PANTRX_142_PE2 NOISO XXXXXXXXXXXXXXXXXXXX---------------------------------------- PONPYXRD_9_PE1 NOISO STQSTFEGFPQSPLQIPVSPSISSTLLSLFHSSPERTQSTFEGFPQSPLQIPVSPSISST MATCH CONSENSUS ??QS??EG??QS?LQ?P???????????????????????????????????????????

CALJAACFV01184156_1_PE1 ISOFORMIN ----------SPQSPPEGPAQSPLLSPVSSS--STSLSLLQSFPENPQSPPEGPAQPIFQ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 SLCLLQSSPESPQSPPEGPAQSPLLSPVSCS--STSLSLPHSFPESPRIPPEGLSQSPLQ HSX_PE2515 ENSG00000155495 LLSIFQSSPERTQSTFEGFAQSPLQIPVSPSSSSTLLSLFQSFSERTQSTFEGFAQSSLQ PANTRX_142_PE2 NOISO -----------------X-------------XXXXXX----------------------- PONPYXRD_9_PE1 NOISO LLSIFQSSPERTQSTFEGFPQSPLQIPVSPSFSSTLLSLFHSSPERTQSTFEGFPQSPLQ MATCH CONSENSUS ????????????QS??EG??QSPL??PVS?S??ST?LSL??S??E??????EG??Q???Q

CALJAACFV01184156_1_PE1 ISOFORMIN RFVSS-FLLHSLRFLQSSSESPQSPPEGPAQSPLLSPVSSSSTSLC--LPPSSPESPHPM CALJAACFV01184156_1_PE2 ENSCJAG00000034873 SPVSS-FSSSSLRFLQSSSESPQSPPEGPAQSPLLSPVSSSSTSLC--LPPSSPESPQCP HSX_PE2515 ENSG00000155495 IPVSPSFSSTLVSLFQSSPERTQSTFEGFPQSPLQIPVSSSSSSTLLSLFQSSPERTHST PANTRX_142_PE2 NOISO -----------------------------------------------XXX---------- PONPYXRD_9_PE1 NOISO IPVSPSISSTLLSLFQSSPERTQSTFEGFPQSPLQIPVSPSFSSTFLSIFHSSPERTQST MATCH CONSENSUS ??VS???????????QSS?E??QS??EG??QSPL??PVS?S??S???????SSPE?????

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 -PEWPAQSPLLSFVSSFSSISLRLSLSSPESPPEGPAEFALPSL----ECSFSSTSLNLL HSX_PE2515 ENSG00000155495 FEGFPQSLLQIPMTSSFSSTLLSIFQSSPESAQSTFEGFPQSPLQIPGSPSFSSTLLSLF PANTRX_142_PE2 NOISO -------------------------XXXXXXXXXDFEGFPQ-SLQIPVSPSFSSTLMSLF PONPYXRD_9_PE1 NOISO FEGFPQSPLQIPVSPSFSSTLLSLFQSSPERTQSTFEGFPQSPLQIPVSPSFSSTFLSIF MATCH CONSENSUS ??????????????????????????????????????F????L??????SFSST?????

CALJAACFV01184156_1_PE1 ISOFORMIN -----------------------SSFSSL------------------------------- CALJAACFV01184156_1_PE2 ENSCJAG00000034873 QNFPESP---SEGPAQSPPRSPMSSFSSLSSSPLCLLQSSLESPQNPSEGPAQSALQSFV HSX_PE2515 ENSG00000155495 QSSPERTHSTFEGFPQSPLQIPMT--SSFSSTLLSILQSSPESAQSAFEGFPQSPLQIPV PANTRX_142_PE2 NOISO QSSPERTQSTFEGFAQSPLQIPVS--RSFSSTLLSIFQSSPERSQRTSEGFAQSPLQIPV PONPYXRD_9_PE1 NOISO QSSPESTQSTFEGFPESPLQIPVS--ASFSSTLLSIFQSSPDSTQSTFEGFPQSPLQIPV MATCH : *: CONSENSUS Q??PE??????EG???SP???P?S???S?SS??L???QSS????Q???EG??QS?LQ??V

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 RS-------------------------------------VFSDCLSLLESSPECPQSPPE HSX_PE2515 ENSG00000155495 SSSFSYTLLSLFQSSPERTHSTFEGFPQSPLQIPVSSSSSSSTLLSLFQSSPECTQSTFE PANTRX_142_PE2 NOISO SSSSSSTLLSLFQSSSERTHSTFEGFPQSPLQIPVSPSSSSSTLLSLFQSSPECTQSTFE PONPYXRD_9_PE1 NOISO SPSISFTLLSLFQSSPERTQSTFEGFPPSPLQIPVSPS-ISSTLLSIFQSSPERTQSTFE MATCH CONSENSUS ?????????????????????????????????????????S??LS???SSPE??QS??E

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 GPSQSALQGPVSS-----SFSPLSFPPSSPEC---------PQSPPEGPSQSALQGPVSS HSX_PE2515 ENSG00000155495 GFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDS--------- PANTRX_142_PE2 NOISO GFPQSPLQIPQSPSERENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDS--------- PONPYXRD_9_PE1 NOISO GFPQSPLQIPQSPPEGENTHSPLQIAQSIPEWEDSLSPHYFPQSPPEGEDS--------- MATCH CONSENSUS G??QS?LQ?P?S????????SPL????S?PE??????????PQSPP?G????????????

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 FFGPLSFPPSSP---------ECPQSPPEGPSQSAL-----QGPVTSFSFSPLSFPPSFP HSX_PE2515 ENSG00000155495 -LSPHYFPQSPPQGEDSLSPHYFPQS-PQGEDSLSPHYFPQSPPQGEDSMSPLYFPQ--- PANTRX_142_PE2 NOISO -LSPHYFPQSPPQGADSLSPHYFPQSPPQGADSLSPHYFPQSPPQGADSLSPHYFPQ--- PONPYXRD_9_PE1 NOISO -LPPHYFPQSPPQGEDSLSPHYIPQSPPQGEDSLSPHYFPQSPPQGEDSLSPHYFPQNPP MATCH CONSENSUS ???P??FP?S?P???????????PQS?P?G?????????????P????S?SP??FP????

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 VCPQSPEGPFQSALQGPVTSFSF-SPLSFPPSSPVC----------PQSPEGP------- HSX_PE2515 ENSG00000155495 -SP-LQGEEFQSSLQSPVSICSSSTPSSLPQSFPESS---------QSPPEGP------- PANTRX_142_PE2 NOISO -I------------------C-SSSPSSLPQSFPESS---------QSPPEGP------- PONPYXRD_9_PE1 NOISO EGEDSLSPHYIP--QSPPEGEDSLSPHYIPQSPPQGEDSLSPHYIPQSPPQGEDSLSPHY MATCH CONSENSUS ?????????????????????????P???P?S?P???????????????P?G????????

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 ----------FQSALQGP--------------------VTSSSFSPLSFPPSSPVFPQSP HSX_PE2515 ENSG00000155495 ----------VQSPLHSPQSPPEGMHSQSPLQSPESAPEGEDSLSPLQIPQSPLEGED-- PANTRX_142_PE2 NOISO ----------VQSPLHSPQSPPEGMHSQSPLQSPESAPEGEDSLSPLQIPQSPPEWED-- PONPYXRD_9_PE1 NOISO FPQSPPQGEDSLSPHYFPQNPPEGEDSLSPHYIPQSPPEGEDSLSPHYIPQSPPQGED-- MATCH CONSENSUS ????????????S????P????????????????????????S?SP???P?S????????

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 ECSSRSALQSPVTPFS----FGPLSLTPSSPECSQSPSEGP-AQSPPQSPVSSFSLSSSP HSX_PE2515 ENSG00000155495 ---SLSSLHFPQSPPEWEDSLSPLHF-------PQFPPQGEDFQSSLQSPV-SICSSSTS PANTRX_142_PE2 NOISO ---SLSALQIPQSPPEWEDSMSPLHF-------PQFPPQGEDFQSSLQSPV-SICSSSTS PONPYXRD_9_PE1 NOISO ---SLSPHYFPQSPPEGEDSLSPHYI----PQSPQSPPEGEDFQSSLQSPV-SICSSSTS MATCH CONSENSUS ???S?S????P??P????????P???????????Q?P??G???QS??QSPV?S???SS??

CALJAACFV01184156_1_PE1 ISOFORMIN ------------------------------------------------------------ CALJAACFV01184156_1_PE2 ENSCJAG00000034873 LCVLQSSPERPQNPSEGPAQSALQSFVRSFFSDCL-SLLESSPECPQSPPEDPSQSSLQG HSX_PE2515 ENSG00000155495 LSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQS PANTRX_142_PE2 NOISO LSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQS PONPYXRD_9_PE1 NOISO LSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSYESPQSPPEGPAPSPLQS MATCH CONSENSUS L???QS?PE?PQ?P?EGPAQS?LQ??V?SFFS??L?SLL?SS?E?PQSPPE?P??S?LQ?

CALJAACFV01184156_1_PE1 ISOFORMIN ---------------------------------SSISPRSALQGPVGSFYSSTLWNPSSE CALJAACFV01184156_1_PE2 ENSCJAG00000034873 PVSSFSFSPFSLT-PGSPVCP--QSPAEGPSQ-SAPQGPSALQGPVGSFYSSTLWNPSSE HSX_PE2515 ENSG00000155495 PVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPES---PLQSPVISFSSSTSLSPFSE PANTRX_142_PE2 NOISO PVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPQSSLQSPVSSFSSSTSLSPFSE PONPYXRD_9_PE1 NOISO PVS--------------------------------------------SFSSSASLSPFSE MATCH ** **: .* ** CONSENSUS PVS??????????????????????????????S???????LQ?PV?SF?SST???P?SE

CALJAACFV01184156_1_PE1 ISOFORMIN ESSSPADEDTRTSDTLLDSESLTDNESLTATEPLVAHTLDEKVDELVRFLLLKYQAKEPV CALJAACFV01184156_1_PE2 ENSCJAG00000034873 ESSSPADEDTRTSDTLLDSESLTDNESLTATEPLVAHTLDEKVDELVRFLLLKYQAKEPV HSX_PE2515 ENSG00000155495 ESSSPVDEYTSSSDTLLESDSLTDSESLIESEPLFTYTLDEKVDELARFLLLKYQVKQPI PANTRX_142_PE2 NOISO ESSSPVDEYTSSSDTLLESDSLTDSESLIESEPLFTYTLDEKVDELARFLLLKYQVKQRI PONPYXRD_9_PE1 NOISO QSSNPVDEDTSTSDTLLESDSLTESESLIESEPLFTHTLDEKVDELVQFLSLKYQAKQPV MATCH :**.*.** * :*****:*:***:.*** :***.::*********.:** ****.*: : CONSENSUS ESSSP?DE?T??SDTLL?S?SLTD?ESL???EPL???TLDEKVDEL?RFLLLKYQ?K?P?

CALJAACFV01184156_1_PE1 ISOFORMIN TKAEMLTIFVNRYRGYFPMIFRKAREFIEILFGIALTEVGPDHSYVFVNTLDLTCEGSLS CALJAACFV01184156_1_PE2 ENSCJAG00000034873 TKAEMLTIFVNRYRGYFPMIFRKAREFIEILFGIALTEVGPDHSYVFVNTLDLTCEGSLS HSX_PE2515 ENSG00000155495 TKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDPDDSYVFVNTLDLTSEGCLS PANTRX_142_PE2 NOISO TKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDPDDSYVFVNTLDLTSEGSLS PONPYXRD_9_PE1 NOISO TKAEMLTNVISRYTGYFPVIFRKAREYMEILFGISLREVDPDDSYVFVNTLDLTSEGSLS MATCH ******* .:.** ****:*******::******:* **.**.***********.**.** CONSENSUS TKAEMLT????RY?GYFP?IFRKAREFIEILFGI?L?EV?PD?SYVFVNTLDLT?EGSLS

CALJAACFV01184156_1_PE1 ISOFORMIN DEQGMPQNRLLTLILSIIFIKGSCASEEVIWHVLNGIGVCAGREHFIFGEPRELLTKVWV CALJAACFV01184156_1_PE2 ENSCJAG00000034873 DEQGMPQNRLLTLILSIIFIKGSCASEEVIWHVLNGIGVCAGREHFIFGEPRELLTKVWV HSX_PE2515 ENSG00000155495 DEQGMSQNRLLILILSIIFIKGTYASEEVIWDVLSGIGVRAGREHFAFGEPRELLTKVWV PANTRX_142_PE2 NOISO DEQGMPQNRLLILILSIIFIKGTYASEEVIWDVLSGIGVRAGREHFAFGEPRELLTKVWV PONPYXRD_9_PE1 NOISO DEQGMPQNPLLIFVLSIIFMKGTCASEEVIWYVLNGMGVYAGREHFVFGEPRELLTKVWV MATCH *****.** ** ::*****:**: ******* **.*:** ****** ************* CONSENSUS DEQGMPQNRLL?LILSIIFIKG??ASEEVIW?VL?GIGV?AGREHF?FGEPRELLTKVWV

CALJAACFV01184156_1_PE1 ISOFORMIN QEHYLEYREVPNTSPPRYEFLWGPRAHSEISKRKVVEFLAMLNNTVPRSFSPSYKDALKH CALJAACFV01184156_1_PE2 ENSCJAG00000034873 QEHYLEYREVPNTSPPRYEFLWGPRAHSEISKRKVVEFLAMLNNTVPRSFSPSYKDALKH HSX_PE2515 ENSG00000155495 QEHYLEYREVPNSSPPRYEFLWGPRAHSEVIKRKVVEFLAMLKNTVPITFPSSYKDALKD PANTRX_142_PE2 NOISO QERYLEYREVPNSSPPRYEFLWGLRAHSEVIKRKVVEFLAMLNNTVPITFPSSYKDALKD PONPYXRD_9_PE1 NOISO QEHYLEYQEVPNTSPPCYEFLWGPRAHSEIIKRKVVEFLAMLNNTVPVSFPSSYKDALKD MATCH **:****:****:*** ****** *****: ***********:**** :*..*******. CONSENSUS QEHYLEYREVPN?SPPRYEFLWGPRAHSE??KRKVVEFLAMLNNTVP??F??SYKDALK?

CALJAACFV01184156_1_PE1 ISOFORMIN LEERAQATIDTTDDSTVTDGASSDVSQPVF--- CALJAACFV01184156_1_PE2 ENSCJAG00000034873 LEERAQATIDTTDDSTVTDGASSDVSQPVFP-- HSX_PE2515 ENSG00000155495 VEERAQAIIDTTDDSTATESASSSVMSPSFSSE PANTRX_142_PE2 NOISO VEERAQAIIDTTDDSTATESASSSVVSPSFSSE PONPYXRD_9_PE1 NOISO AEKRAQAIIDTTDDSTATESASSSVMSPSFSSE MATCH *:**** ********.*:.***.* .* * CONSENSUS ?EERAQA?IDTTDDST?T??ASS?V??P?F???


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