Alignment of the gene Family HOG000113723 of HOGENOM

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Threshold: 50% 80% 100%
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Isoforms are ON
AILMEGL193092_1_PE26 NOISO ------------------------------------------------------------ CALJA8_14_PE6 NOISO ------------------------------------------------------------ CAVPO66_3_PE3 NOISO ------------------------------------------------------------ FELCAGS_2169_PE3 NOISO ------------------------------------------------------------ GORGO7_48_PE11 ENSGGOG00000000831 ------------------------------------------------------------ HS7_PE1372 NOISO ------------------------------------------------------------ LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 ------------------------------------------------------------ MONDO6_282_PE19 ISOFORMIN ------------------------------------------------------------ MOUSE11_PE263 NOISO SALPLALRSARRAGARSLGLIGGRGSADVIYAPPPPSRGAVAVLATPSALTDRGTERQGY PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO ------------------------------------------------------------ PROCA10738_PE1 NOISO ------------------------------------------------------------ PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO ------------------------------------------------------------ RAT14_PE922 NOISO SALPLALRSARRAGARSLGLIGGRGSADVIYAAPPPSRGAVAVLATPSALTDRGTERQGY MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO -------MPGEAARAEPLLPEAGRPGPRTESSCDVAVA-TTPRGDRLEHCALTPGPSALA CALJA8_14_PE6 NOISO -------MPGEAARAELLLPEGDGPGPRTDLSCDAAAATSILGGDRREPCALTPGPSHLA CAVPO66_3_PE3 NOISO -------MPGEAARAELPLPEADGTEPHTDLTCDVPAA-TILGGEQRDPHALTPGPSPLA FELCAGS_2169_PE3 NOISO -----------------------------------------------EHCALSPGPGGLA GORGO7_48_PE11 ENSGGOG00000000831 -------MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLA HS7_PE1372 NOISO -------MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLA LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 ------------------------------------AAASTPSGDSSIRGDLTPGPVSIP MONDO6_282_PE19 ISOFORMIN ---------------------------------------------------MTPGPVSIP MOUSE11_PE263 NOISO RQAHVQAMPGEAAGAELPLPEAGGPGSRTDHSCDAAIA-TILKGDQLEPHGLTPGPSPLA PANTR7_50_PE19 NOISO -----------------------------------------------DPCALTPGPSHLA PIG18_51_PE9 NOISO -------MPGEAARAELLLPEAGGPGPRTDLSCDAAAA-TTPKGDRLEHCALSPGPSTLA PROCA10738_PE1 NOISO -----------------------------------------------EHCTPPPRTSPLT PTEVAGS_1659_PE2 NOISO -----------------------------------------------QPCALTPGPSALA RABIT10_47_PE33 NOISO -------MPGEAARAELLLPGGSRAGLSTDLSCDAVAA-TIPGGDLQQPQALTPGSSPLA RAT14_PE922 NOISO RQAHVQAMPGEAAGAELPLPEAGGSGSRTDLPCDAAIA-TILKGDQREPHGLTPGPSPLA MATCH CONSENSUS ???????????????????????????????????????????????????L?PGP??L?

AILMEGL193092_1_PE26 NOISO LEFLPSKPGARPPPEGASWDAGPGGTPSAWVVPAEGDPSPG------PPEAQPAGGPPPA CALJA8_14_PE6 NOISO LTFLPSKPGARPQPEGASWDAGPGGASSAWADPAEGSLSPKLLPEGLS-QVLPTETPLPA CAVPO66_3_PE3 NOISO LAFLPSKPGTRPQPEGASWDAGPGGGPSAWADPAEGSL--NLLPEGLHPQ------ALPA FELCAGS_2169_PE3 NOISO LEFLPSKPGARPSSEGASWYAGPRGSPSAWAVPARSPQLLL------EP--ARRGVLLQS GORGO7_48_PE11 ENSGGOG00000000831 LTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPA HS7_PE1372 NOISO LTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPA LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 LTFLPSKQGDRPQPEGASSDAGVGSTSSSRTALGECGPVVG-LP-----RSLPEEPLTLE MONDO6_282_PE19 ISOFORMIN LTFLPSKQGDRPQPEGASSDAGVGSTSSSRTALGECGPVVG-LP-----RSLPEEPLTLE MOUSE11_PE263 NOISO LTFLSSKPGARPQPEGASWDAGPSGAASAWVDPAEGSPSLVVLPEGLPLRPVPAEGPLPT PANTR7_50_PE19 NOISO LTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPA PIG18_51_PE9 NOISO LTFLPSKPGTRPPPEGASWDAGPGRAPSAWAVQTEGGPSPG------SPEVRPAEGPLPA PROCA10738_PE1 NOISO VMFLPSKSGTRPQPEGASWDAGPDRALSAWALSAEGSTSPV------PPEGQLT-EALSA PTEVAGS_1659_PE2 NOISO LTFLPSKPGARPPPEGASWDAGSHQAPSTWAVPAKSSPSGP--------EVLPIGGPVPG RABIT10_47_PE33 NOISO LSFLPSKPGARPQPEGASWDAGPGGASSAWADAAEGGPSPTLLPEGPPSQALSPE-ALPS RAT14_PE922 NOISO LTFLSSKPGARPQPEGASWDAGPSGAASTWVDPAEGSPSLVVLPEGLPLRPVPADVPLPT MATCH CONSENSUS L?FLPSK?G?RP?PEGASWDAG?????S?W????E?????????????????????????

AILMEGL193092_1_PE26 NOISO TLEPRIVMGEETRR-VPQPSR--------------AALPELRDREGGYRSLDPSPELCSQ CALJA8_14_PE6 NOISO TLEPRIVMGEETCQ-ALLSPR--------------AARTALRDQEGGHESLDPPPELCSQ CAVPO66_3_PE3 NOISO TLEPRIVMGEETCQ-APPSPR--------------AVLPALREQ-----------ELCSQ FELCAGS_2169_PE3 NOISO TLKPRIVMGEEXXX-XXXX-P--------------RAAPELRDREGGHPSPDPPSELCSQ GORGO7_48_PE11 ENSGGOG00000000831 TLEPRIVMGEETCQ-ALLSPR--------------AARTALRDREGGHASPDPPPELCSQ HS7_PE1372 NOISO TLEPRIVMGEETCQ-ALLSPR--------------AARTALRDQEGGHASPDPPPELCSQ LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 GLEPRVVMGEETNGSGPRQAAAELPKEPLAAEPLMVTASELRDLEGRRAGPSPPPELLSQ MONDO6_282_PE19 ISOFORMIN GLEPRVVMGEETNGSGPRQAAAELPKEPLAAEPLMVTASELRDLEGRRAGPSPPPELLSQ MOUSE11_PE263 NOISO TLEPRIVMGEETCQ-VIASPR--------------AAWPVLRDREGGHPALHPPPELCSQ PANTR7_50_PE19 NOISO TLEPRIVMGEETCQ-ALLSPR--------------AARTALRDREGGHTSPDPPLELCSQ PIG18_51_PE9 NOISO SLEPRIVMGEETCRRAPPLPR--------------AALPELRDWEGGHASPHPPPELRSQ PROCA10738_PE1 NOISO TLEPRIVMGEENCR-PPTRPR--------------AASQELRDWEGGHANLNLPPELCSQ PTEVAGS_1659_PE2 NOISO ALEPRIAMGEETRR-APPLPW--------------AALPELRDRVRGPASPSPPPAAHPQ RABIT10_47_PE33 NOISO SLEPRIVMGEETCQ-APASPW--------------AAGPALRDREGGRAGLHPPPEPCSQ RAT14_PE922 NOISO TLEPRIVMGEETCQ-VLPSPR--------------AAWPVLRDREGGHTALHPPPELCSQ MATCH CONSENSUS ?LEPRIVMGEET????????????????????????????LRD?EG??????PP?EL?SQ

AILMEGL193092_1_PE26 NOISO GDPPVPCPAPDPDSYFTPPSTPTETASALLLGPGPRREAREAPAEP----GDSPPASPSG CALJA8_14_PE6 NOISO GDLSVPFPPPDPDSFFTPPSTPTKTIYALLPGSGPLGDVQDSEAEMQDELLDSSPASPSG CAVPO66_3_PE3 NOISO DDPPVPSWSPDPEPYFTPPSTPTKATCTLLLSPGLHRDTWDPEAELLD----SLASSPSG FELCAGS_2169_PE3 NOISO GDPPVPCPAPDPDSYFTPPSTPTETTCALLLGAGPRRDARDTQAEL----GDSPPASPSG GORGO7_48_PE11 ENSGGOG00000000831 GDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPHGDARDSEAELRDELLDSPPASPSG HS7_PE1372 NOISO GDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSG LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 GDLPVPSPRLDPDPYFTAPSTPTKLACSYLFSHTLCLSEEPSD--TEADILGSPPTSPSG MONDO6_282_PE19 ISOFORMIN GDLPVPSPRLDPDPYFTAPSTPTKLACSYLFSHTLCLSEEPSD--TEADILGSPPTSPSG MOUSE11_PE263 NOISO GDPPVPSPPPDLESYFTPPSTPTKSTHALLPDHGPHRDAWDLEAELLDELLDSTPASPSG PANTR7_50_PE19 NOISO GDLSVTYPPPDPDSFFTP-------------------------------------ASPSG PIG18_51_PE9 NOISO GDPPVPFPAPDSDSFFTPPSTPTETACPLLPGPGPRRDAGDAQAEL----GDSPPASPSG PROCA10738_PE1 NOISO GDSPVPFPHPDPDSYFTPPSTPLQTTCALAVGLGLCTEACDSEAEL----LDSPPTSPSG PTEVAGS_1659_PE2 NOISO GALLTPVPATDPDCYFTPPSSPSQTTATLLPGRG-----WAAETELQTEPGDSPPASPSG RABIT10_47_PE33 NOISO GDPPVPSPPPDPDSFFTPPSTPTKTTYSLLPSHG---DSWDPEPE-----LDSPPASPSG RAT14_PE922 NOISO GDPPVPSPPPDLDSYFTPPSTPTKTTYALLPDHGPHRGAWGLEAELLDELLDSTPASPSG MATCH CONSENSUS GD??VP?P??D?D??FTPPSTP???????L??????????????????????S?P?SPSG

AILMEGL193092_1_PE26 NOISO SYITADGDSWAS------SLSCSLSLLAPAEGLDVPSGWGFSPPG-SVADEQELPPMGLP CALJA8_14_PE6 NOISO SYITADGNSWAS------SPSCSLSLLAPDEGLDFPSGWGLSPQG-SMADERELHPAGTP CAVPO66_3_PE3 NOISO SYVTADGDSGTL------SPSCSLSLLAPTEGLDFPSGWSLSQPE-SVAEEWEPPPAE-- FELCAGS_2169_PE3 NOISO SYITADGDSWAS------SPSCSLSLLVPAEGLDVPSGWGFSPPG-SVADEQEPSPAGPP GORGO7_48_PE11 ENSGGOG00000000831 SYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLSPRG-SMVDERELHPAGTP HS7_PE1372 NOISO SYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLSPQG-SMVDERELHPAGTP LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 SYITAEGGSWASSSSFSTSPSCSPNLLMETEGPDSPGNRDSPLDGASDSDDTELLPSGPQ MONDO6_282_PE19 ISOFORMIN SYITAEGGSWASSSSFSTSPSCSPNLLMETEGPDSPGNRDSPLDGASDSDDTELLPSGPQ MOUSE11_PE263 NOISO SYITADGDSWAS------SPSCSLSLLDPAEGLDFPSDWGLSPSG-SVADDLEPHPAAPP PANTR7_50_PE19 NOISO SYITADGYSWAS------SPSCSLSLLAPAEGLDFPSGWGLSPRG-SMVDERELHPAGTP PIG18_51_PE9 NOISO SYVTADGDSWAS------SPSCSLSLQAPAEGLDGPQXKRT------------------- PROCA10738_PE1 NOISO SYITADGDSWAS------SPSCSLNVLAPVQGPDLPSGWDFSPSG-PMAEGREPPAVRPP PTEVAGS_1659_PE2 NOISO SYVTADGDSWGS------SPSCSLSLLAVAEGLDVPSGWSFSPPG-SEANEREPTPAESL RABIT10_47_PE33 NOISO SYITADGDSWAS------SPSCSLSLLALAEGLDFPSSWGLSPPG-SVVDEGERSPPRPP RAT14_PE922 NOISO SYITADGDSWAS------SPSCSLSLLAPAEGLDFPSEWGLSPSG-SVVDELEPHPTAPP MATCH CONSENSUS SY?TADG?SWAS??????SPSCSL?LL???EG?D?P????????G?S?????E??P????

AILMEGL193092_1_PE26 NOISO GPPSPESSISADSSSSWGQ---EGHFFELDFLANDPMIPAALLPFRGSLIVQVEAVEVTP CALJA8_14_PE6 NOISO ESQSSESSLSTDSSSSWGQ---EGHFFDLDFLANDPMIPATLLPFQGSLIFQVEAVEVTP CAVPO66_3_PE3 NOISO -TPSSESSLSGDSGSSWGQ---EGHFFDLDFLANDPMIPAALLPFQGSLIFQVESVEVTP FELCAGS_2169_PE3 NOISO GPPSPESSISADSSSSWGQ---DGHFFELDFLANDPMIPASLLPFRGSLLFQVEAVEVTP GORGO7_48_PE11 ENSGGOG00000000831 EPPSSESSLSADSSSSWGQ---EGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTP HS7_PE1372 NOISO EPPSSESSLSADSSSSWGQ---EGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTP LOXAF63_14_PE6 ENSLAFG00000007691 -------------------------------------------PFQGSLIFQVDAVEVLL MONDO6_282_PE18 ENSMODG00000010591 DLPSSESSLSGDSGSSWSTGRREHPFPEAGFPGSEPMIPATLLPFRGSLIFEADAVEIML MONDO6_282_PE19 ISOFORMIN DLPSSESSLSGDSGSSWSTGRREHPFPEAGFPGSEPMIPATLLPFRGSLIFEADAVEIML MOUSE11_PE263 NOISO EPPSSESSLSADSSSSWSQ---EGHFFDPNFLANDPMIPAALLPFRGSLIFQVEAVEVTP PANTR7_50_PE19 NOISO EPPSSESSLSADSSSSWGQ---EGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTP PIG18_51_PE9 NOISO ------------------------HFRER----------------RGE-----------P PROCA10738_PE1 NOISO SSYSSASSLSADSSSSWGQ---EGNLLDLDFMANDPMIPAALLPFQGSLIFQVDAVEVML PTEVAGS_1659_PE2 NOISO GSPSPESSLSGDSSSSWDQ---EGHFFELDFLANDPMIPAALLPFRGSLIFQVEAVEVTP RABIT10_47_PE33 NOISO GAPSTESSLSADSSSSWGQ---EGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAMEVTP RAT14_PE922 NOISO EPPSSESSLSADCSSSWSQ---EGHFFDPNCLANDPMIPAALLPFRGSLIFQVEAVEVTP MATCH :*. CONSENSUS ???S?ESS?S?DS?SSW?????E??F????F????PMIPA?LLPF?GSLIFQV?AVEV??

AILMEGL193092_1_PE26 NOISO RAP-EDDEQEED----------IPVPGEDPAGEGEDDSTFASSLQSLSDLSITEGMDEAF CALJA8_14_PE6 NOISO LSPEEEEEEV----------EAAPSPGGDLAGDGEEDSTSASFLQSLSDLSITEGMDEAF CAVPO66_3_PE3 NOISO LPAEEEEEEVA---------ADTPAPAGEAAGED-EDSTSASFLQSLSDLSITEGMDEAF FELCAGS_2169_PE3 NOISO RAP-EEEEEEEEEE---EEEEDGRDSAGDPAGEGEDDSTFASSLQSLSDLSITEGMDEAF GORGO7_48_PE11 ENSGGOG00000000831 LSPEEEEEEA----------VADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAF HS7_PE1372 NOISO LSPEEEEEEA----------VADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAF LOXAF63_14_PE6 ENSLAFG00000007691 LPTPEEE--------------KAPGSAGDLSGEGEEDSTSASFLQSLSDTSIIEGVDEAF MONDO6_282_PE18 ENSMODG00000010591 LPQEEALSR---------------------DSEGEDDSTSASFLQSLSEMSINEGVDEAF MONDO6_282_PE19 ISOFORMIN LPQEEALSR---------------------DSEGEDDSTSASFLQSLSEMSINEGVDEAF MOUSE11_PE263 NOISO LPQEEEEDEEDVAATAAAAAPAAATPDGDLAGEGEDDSTSASFLQSLSDLSIIEGMDEAF PANTR7_50_PE19 NOISO LSPEEEEEEA----------VADPDAGGDLAGEGE-DSTSASFLQSLSDLSITEGMDEAF PIG18_51_PE9 NOISO LPPEEEGVQEEQEQ---DEEQEAPVPRGDLAGEGEDDSTFASSLHSLSDLSITEGMDEAF PROCA10738_PE1 NOISO LPGPEEE------E---KSETKAPGPGRDLGEEGEDDSPSASFLQSLSDISIIEGMDEAF PTEVAGS_1659_PE2 NOISO LPPEEEPDGE-----------------------DGDGSTFASSLQSLSDLSITEGVDEAF RABIT10_47_PE33 NOISO LHAV----------------GAAPAPGRDLAGEGEDDSTSTSFLQSLSDLSITEGMDEAF RAT14_PE922 NOISO LPQEEEEDEEEGAA---AAAAAAATPDGDLAGEGEDDSTSASFLQSLSDLSIIEGMDEAF MATCH . .*. :* *:***: ** **:**** CONSENSUS L???E???????????????????????????EGE?DST?AS?LQSLSD?SI?EG?DEAF

AILMEGL193092_1_PE26 NOISO AFRDDTSAASSDPD--SASYAGADDERLYSEEPHARPAALLPDSPG-------------- CALJA8_14_PE6 NOISO AFRDDTSAASWDSD--SASYAEADDERLYSGEPHAQPTLLQDSVQKT-EEESGGGAQGLQ CAVPO66_3_PE3 NOISO AFRDDTSAASSDSD--SASYAGADDDRLYSGEPHAQPSVLLLDTGQKAEQECADRA---- FELCAGS_2169_PE3 NOISO AFRDDTSAASSDPD--SASYAGADDERLYSGEPHAQPAALLQDALA-------------- GORGO7_48_PE11 ENSGGOG00000000831 AFRDDTSAASSDSD--SASYAEADDERLYSGEPHAQATLLQDSVQKT-EEESRGGAKGLQ HS7_PE1372 NOISO AFRDDTSAASSDSD--SASYAEADDERLYSGEPHAQATLLQDSVQKT-EEESGGGAKGLQ LOXAF63_14_PE6 ENSLAFG00000007691 AFRDDTSAASSDSD--SASYAGADDERLYSGEPHAQPSTLLQDSRCKVEER--------- MONDO6_282_PE18 ENSMODG00000010591 AFRDDTSAASSDSD--SVSYAGEEDERLYSEEPHAQPPAPLWLGSPESGENLADKKEELG MONDO6_282_PE19 ISOFORMIN AFRDDTSAASSDSD--SVSYAGEEDERLYSEEPHAQPPAPLWLGSPESGENLADKKEELG MOUSE11_PE263 NOISO AFRDDTSAASSDSD--SASYAGADDDRLYSGEPHAQPSAQNTEQAYR-S----------- PANTR7_50_PE19 NOISO AFRDDTSAASSDSD--SASYAEADDERLYSGEPHAQATLLQDSVQKT-EEESGGGAKGLQ PIG18_51_PE9 NOISO AFRDDTSAASSEPD--SASYAGADDERLYSGEPHAQPTTLLQDSPA-------------- PROCA10738_PE1 NOISO AFRYDTSAASSDSDSASASYAGADDERFYSGELPVQPSALLQDCRCKVEER--------- PTEVAGS_1659_PE2 NOISO AFRDDASAASSDPD--SASYTGVEDERLYSEEPHAQPPLPAPWGTAP------------- RABIT10_47_PE33 NOISO AFRDDTSAASSDSD--SASYAGADDERLYSGEPHAQPSAPFLEGTQKAEQECRAAAEQLR RAT14_PE922 NOISO AFRDDTSAASSDSD--SASYAGADDDRLYSGEPHAQPSAQNIEQEYR-S----------- MATCH *** *:**** :.* *.**: :*:*:** * .:.. CONSENSUS AFRDDTSAASSD?D??SASYA?ADDERLYS?EPHAQP???????????????????????

AILMEGL193092_1_PE26 NOISO ------EP---------APAVSEGGAGRATESQEPGAQVPEAGHASGQASAAAAAPHTPQ CALJA8_14_PE6 NOISO ALEGTEF-----WALEAVSQTSDRGAH-LSQRQESISEVTEEGLALGQQSTATVTPHTLQ CAVPO66_3_PE3 NOISO -----VFWAAEAMGTVRTPQVPEGEAC-LSQSQESITGVMEEGLASSQEPAAAVTPHTGQ FELCAGS_2169_PE3 NOISO -----------------APGISEGEAGRAMESHEPGAQETGA-----------VPAPALQ GORGO7_48_PE11 ENSGGOG00000000831 AQEGTVS-----WALEAAPQTSDRGAY-LSQRQELISEVTEEGLALGQESTATVTPHTLQ HS7_PE1372 NOISO AQDGTVS-----WAVEAAPQTSDRGAY-LSQRQELISEVTEEGLALGQESTATVTPHTLQ LOXAF63_14_PE6 ENSLAFG00000007691 ----QEDWAPSLGQQEPMPVVSKGEVVEIMATQV------------------------PC MONDO6_282_PE18 ENSMODG00000010591 S-----ICLPARWTEPAAMALTPQGLKEMDLKSI-----------------EVTTSHSTQ MONDO6_282_PE19 ISOFORMIN S-----ICLPARWTEPAAMALTPQGLKEMDLKSI-----------------EVTTSHSTQ MOUSE11_PE263 NOISO --RATFP-----GI-ESTPQTSEQEIC-LTNSQESVAEIAEEILTLGLESEAMRTPPDQQ PANTR7_50_PE19 NOISO AQEGTVS-----WALEAAPQTSDRGAY-LSQRQESISEVTEEGLALGQESTATVTPHTLQ PIG18_51_PE9 NOISO ------DAA--FWGPEPALGAAPREAGTAAKSQEPGSEIPEVGPTSGQASAAGVGPHIPQ PROCA10738_PE1 NOISO ----RDGPL--FWAEEPTPWTERRSLKTLTQDVAEG-------FLSVQD----------- PTEVAGS_1659_PE2 NOISO --------GVSDWAEL---------------------EITRAGPTSGQVSAASPALPPSQ RABIT10_47_PE33 NOISO GPEGPESCGLEAAGATPTPRVSEREAC-LTQSQDRMETA-GEEHTPGQEATASKTPPALQ RAT14_PE922 NOISO --RTAFP-----GAAEFTPQTSEQEIC-LTDSQESAAEIAEEILTLGIESEATRTPPDRQ MATCH CONSENSUS ???????????????????????????????????????????????????????????Q

AILMEGL193092_1_PE26 NOISO EAPGLTL-----VTPQAWGEEAD------------------SALGPTPIAAGTAQPLRED CALJA8_14_PE6 NOISO VALGLQVEVATRMIPQAGEEEV------------------DSTTGQAPAAMAMPQPSQEG CAVPO66_3_PE3 NOISO ATPGLTPQ-------------V------------------DSVAGRAPATWAPAHPTQDK FELCAGS_2169_PE3 NOISO EAPGRPW-----VTLQAWGEEAG------------------SVLGPAPVATDTLQPLQLE GORGO7_48_PE11 ENSGGOG00000000831 VAPGLQVEVATRVTPQAGEEEA------------------DSTAGQESAAMAMPQPSQEG HS7_PE1372 NOISO VAPGLQVEVATRVTPQAGEEET------------------DSTAGQESAAMAMPQPSQEG LOXAF63_14_PE6 ENSLAFG00000007691 GQEAATA-----VIPHNWQAEAGPGQEDAARVTPPLL--PEEGLTLGEVSMAAPLTLQEE MONDO6_282_PE18 ENSMODG00000010591 EVTDLES-VVVSVTPQTLQE----------------------GVNLEPIAMKTSQAVQEG MONDO6_282_PE19 ISOFORMIN EVTDLES-VVVSVTPQTLQE----------------------GVNLEPIAMKTSQAVQEG MOUSE11_PE263 NOISO AAPGPQVEETPTVTPWVGNKVD-------------------LV--VEQVSKALPEPCQEG PANTR7_50_PE19 NOISO VAPGLQVEAATRVTPQAGEEEA------------------DSTAGQESAAMAMPQPSQEG PIG18_51_PE9 NOISO EAPGLTG-----VTPQAQVEEAG------------------STMGPAPVAMVALGPLKEG PROCA10738_PE1 NOISO ---AAAS-----VTALSWPAEAGLVESAAVGPPQPGEKTADSSVGQEDVAMATPLPLQGK PTEVAGS_1659_PE2 NOISO EAPGLAG-----VPPRALGGEA------------------GSAVGAVPVSMGAPQPWQEG RABIT10_47_PE33 NOISO AAPGPQAAPGPHITPEAEEEEE------------------DSTAGGAPSQAA-PGPHITP RAT14_PE922 NOISO TAPDPQVEEATTVTPWVENKDD-------------------SV--AEQASKALPEPCQKG MATCH . CONSENSUS ????????????V?P????????????????????????????????????????P?Q??

AILMEGL193092_1_PE26 NOISO DSTALGPGPWTTP------EEGALTPSPDSLQNPEKEAGQDDVGLPSGQAPTAE------ CALJA8_14_PE6 NOISO ISEILGQESVTAEKLPTPQEAASLTLCPDSPQNLKEG---GGLDLLSGPKPVAT------ CAVPO66_3_PE3 NOISO KGTAVGQPPDCTEAKPALQEAIGSTMCPESPEPRGHQ-EAPGLPI--------------- FELCAGS_2169_PE3 NOISO DGAAVGLAPCTAP------EEGDLTPSPDSPQTLKQEAGQD------------------- GORGO7_48_PE11 ENSGGOG00000000831 ISEILGQESVTAEKLPTPQEETSLILCPDSPQNLKEE---GGLDLPSGGKPVAA------ HS7_PE1372 NOISO ISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEE---GGLDLPSGRKPVAA------ LOXAF63_14_PE6 ENSLAFG00000007691 VSATLGHETTATEMPQTLKEEVSLVPCPDSLAMSVTL----------------------- MONDO6_282_PE18 ENSMODG00000010591 VDL----EPIATKTSQAVQEGVDLDSI----AMKTSQAVQEGVDLE----PIAMKTSQAV MONDO6_282_PE19 ISOFORMIN VDL----EPIATKTSQAVQEGVDLDSI----AMKTSQAVQEGVDLE----PIAMKTSQAV MOUSE11_PE263 NOISO ISTTLGCKPLTAEAIPDLQEGASPSLCPVLPEK-KEE----GQGLPSTLEYVAV------ PANTR7_50_PE19 NOISO ISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEE----GLDLPSGGKPVAA------ PIG18_51_PE9 NOISO DSPALGTEGSATE------ASPEPQPEER---DLVAPLPLQDAGLPSDQESATE------ PROCA10738_PE1 NOISO VNAALGDEAGAEETPQTVKEKVSIMPCPDSFQKEK------------------------- PTEVAGS_1659_PE2 NOISO AGTALGPRV-----------DQGGAGCPDTPQSVKAG----------------------- RABIT10_47_PE33 NOISO EAKEEEEEDSTAGGAP-SQAAPGPHITPEAEEEKEDS-SAGGAPSPAAPGPQLTPE--AE RAT14_PE922 NOISO TSMILGCKPLTAKAIPDLQEGAGPAMCPVLPENLKEG----GQGLPSTMEYVAV------ MATCH CONSENSUS ?????G?????????????E???????P????????????????????????????????

AILMEGL193092_1_PE26 NOISO ---------VSPVPQPGEADRTSPQDPDSVATLL--------------SLQDEGLPSGQG CALJA8_14_PE6 NOISO ---------ATLVPQQAEEGLTLPQDSA-VTPPL--------------PPQDTDLPSGPE CAVPO66_3_PE3 NOISO -----------QGPL--------------------------------------------- FELCAGS_2169_PE3 NOISO --------------------------PDSVAPAR--------------PPQDTGLPLGQG GORGO7_48_PE11 ENSGGOG00000000831 ---------AMIVPRQAEEDLTLPQDSA-MTPPL--------------PLQDTDLSSAPK HS7_PE1372 NOISO ---------ATIVPRQAKEDLTLPQDSA-MTPPL--------------PLQDTDLSSAPK LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------QNEK--------------EEVGPGLTSGRG MONDO6_282_PE18 ENSMODG00000010591 QEGVDLDPIAMKTSQAVQEGVD--LDPIAMKTSQVVQEGVDLEPIAMKTSQTIQETVGQE MONDO6_282_PE19 ISOFORMIN QEGVDLDPIAMKTSQAVQEGVD--LDPIAMKTSQVVQEGVDLEPIAMKTSQTIQETVGQE MOUSE11_PE263 NOISO ---------ALEGPWKAEGGVTIPQDPL-MTLPP--------------LLQSTVPTSGPE PANTR7_50_PE19 NOISO ---------ATIVPRQAEEDLTLPQDSA-MTLPL--------------PLQDTDLSSAPK PIG18_51_PE9 NOISO ---------ASPEPQPEERDL---------MAPL--------------PLQDAGLPSDQE PROCA10738_PE1 NOISO ------------------------------------------------EEVGPGLTSGQE PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO EEDEDDDSTAGGAPSQAAPGP------H-ITPEA--------------KEEEEDSSAGGA RAT14_PE922 NOISO ---------ASVGPWKAEGGVAIPQDPF-MTLPP--------------LLQNTDPTSGPE MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO TPTEARLQTLQVDAGCVPAIEPVVTAAQPA---TEAPETPEPATEALQHPKPATEAVEFP CALJA8_14_PE6 NOISO PVAVATLVPQQAEEG-LTLPQDSAVTPPLPPQDTDLPSGPEPVAAATLVPQQAEE-GLTL CAVPO66_3_PE3 NOISO ------------------------------------------------------------ FELCAGS_2169_PE3 NOISO PAAAARLQKLHVHT---PRIKPVVTAAQQE---GQTTLEPRPAPEERD------------ GORGO7_48_PE11 ENSGGOG00000000831 PVAAATLVSQEAEEG-LTLPQDSATTPPLPLQDTDLSSAPKPVAAATLVPQQAEE-GLTL HS7_PE1372 NOISO PVAAATIVSQQAEEG-LTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEE-GLTL LOXAF63_14_PE6 ENSLAFG00000007691 SVATATPVPLYEGC--ILCQE--------------------------------------- MONDO6_282_PE18 ENSMODG00000010591 PIATISQTT-------------------------EEAVDLEPMTMKTS---QTIEGALS- MONDO6_282_PE19 ISOFORMIN PIATISQTT-------------------------EEAVDLEPMTMKTS---QTIEGALS- MOUSE11_PE263 NOISO SVAVVALEPQQNEGC-VTVLPDVPVVLPPSPQSVDPSSGPEAMAVATYEFQRAKE-GTPG PANTR7_50_PE19 NOISO PVAAATLVPQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPKPVAVATLVPQQAEE-GLTL PIG18_51_PE9 NOISO SATEASPEPQPEDAD-IPLVQESAT---------EASPEPQPEERDLMAPLPLQDAGLPS PROCA10738_PE1 NOISO SFATATPVHLYKDV---------L----------------------------------RQ PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO P-------------------SQAAPAPQLTPEAEEAATGPQLTPEAEEE--EEED-STAG RAT14_PE922 NOISO SVAVVMLEPQQDEGC-VTVLQDVPVVSLPSPQSTDPTPGPEAGAMATFEFQQAKE-GVPE MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO E-------------PDTEATNCPKPVTEAPECPEPVTEAVECLE----SATEA------- CALJA8_14_PE6 NOISO PQDSAVPPAMPV--P------------------Q---QAEEGLTLPQDSAV--------- CAVPO66_3_PE3 NOISO ------------------------------------------------------------ FELCAGS_2169_PE3 NOISO ----------------TRHAGGP----------EPSAWNQA-----------Q------- GORGO7_48_PE11 ENSGGOG00000000831 PQDSAMTPPLPL--QDTDLSSAPKPVAAATLVSQ---EAEEGLTLPQDSAT--------- HS7_PE1372 NOISO PQDSAMTPPLPL--QDTDLSSAPKPVAAATLVSQ---QAEEGLTLPQDSAM--------- LOXAF63_14_PE6 ENSLAFG00000007691 ----------------------------SVSMTTPVTLQRKA------------------ MONDO6_282_PE18 ENSMODG00000010591 --------------QTTEEAVDLEPVTMKTSQVVQETVDLEPIAIKTSQTI--------- MONDO6_282_PE19 ISOFORMIN --------------QTTEEAVDLEPVTMKTSQVVQETVDLEPIAIKTSQTI--------- MOUSE11_PE263 NOISO LQDSPVAASPAL--QGPDPTSEPEPEVVVTSRSQ---QDEGIVTVPQES----------- PANTR7_50_PE19 NOISO PQDSAMTPPLPL--QDTDLSSAPKPVAAATLVPQ-------------------------- PIG18_51_PE9 NOISO D-------------QESATEASPEPQPEEVDLVAPLPLQDAGLPSDQESATEA------- PROCA10738_PE1 NOISO ---------------------------EPVSMTTSLTLQEKSLTLHQESVS--------- PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO GAPSQAAPGPHITPEAEEEKAAPDPQLTPEAEEEEEEDSTAGGALPQAALGPQLTPEAAT RAT14_PE922 NOISO LQDTPVASSPAL--QASDPTSEPEPEAVLTLRSQ---QDEEIVTVPQES----------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO -------------LECPEPAMEAPEHSKPATEAPECPEPATEAIECLESA--IEALEYPE CALJA8_14_PE6 NOISO PPAPPVPQQAEEGLTLPQDSAVSPATPVPQQAEEG---LTLPQDSAVPPA---------- CAVPO66_3_PE3 NOISO ------------------------------------------------------------ FELCAGS_2169_PE3 NOISO -------------LEGMEPAADTG---------------------TLWAS--RGTAGTPK GORGO7_48_PE11 ENSGGOG00000000831 TPPLPLQDTDLS--S--APKPVAAATLVSQQAEEG---LTLPQDSATTPPLPLQDTDLS- HS7_PE1372 NOISO TPPLPLQDTDLSS----APKPVAAATLVSQQAEEG---LTLPQDSAMTPPLPLQDTDLS- LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 ----------EEA------VDLEPIAIKTSQTIE--------------EAVDLEPIAI-- MONDO6_282_PE19 ISOFORMIN ----------EEA------VDLEPIAIKTSQTIE--------------EAVDLEPIAI-- MOUSE11_PE263 NOISO ---------------------------------------------PTASSLTLQS----- PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO SPEP---QPEERDLVAPLPLQDADIPLVQGFASETSPEPQLEE--DLMASLPLEDADLPL PROCA10738_PE1 NOISO ------------------------------------------------------------ PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO GPQLTPEAKEEDSTTGGAPSQAAPGTQLTPEAKEE------EEEDSTAGGAPFQA----- RAT14_PE922 NOISO ---------------------------------------------PTASSVPLQS----- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO ---PATEALKCPQPAMEAPECPEPATEAPEYSETTTEALEHSEP---------AT-ED-P CALJA8_14_PE6 NOISO ------------------PP----------VPQQAEEGLTL-PQDSAVPPAPP------- CAVPO66_3_PE3 NOISO ------------------------------------------------------------ FELCAGS_2169_PE3 NOISO ---SATEAAQPPQPAXXXXX---------------------------------------- GORGO7_48_PE11 ENSGGOG00000000831 ---------SAPKPVAAATL----------VPQQAEEGLTL-PQDSAMTPPLPLQDTDLS HS7_PE1372 NOISO ---------SAPKPVAAATI----------VSQQAEEGLTL-PQDSAMTPPLPLQDTDLS LOXAF63_14_PE6 ENSLAFG00000007691 ------------------------------------------------------------ MONDO6_282_PE18 ENSMODG00000010591 -----------------------------KTSQTIEEAVDLEPVIMK-------TSQVVQ MONDO6_282_PE19 ISOFORMIN -----------------------------KTSQTIEEAVDLEPVIMK-------TSQVVQ MOUSE11_PE263 NOISO --------------------------------------------------------SHPT PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO VQGSDSEASPEPQPGQGS------------ASET-------------------------- PROCA10738_PE1 NOISO ------------------------------------------------------------ PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO ----------APGPQLT-PE----------VKEEEEEDSTAGGAPSQVAPGPQLTPEA-K RAT14_PE922 NOISO --------------------------------------------------------SDPT MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO EHPEPATEAPECPELATEDPEFPEPATEALEHS---EPAM-EDP-EHPEP----VTEAPK CALJA8_14_PE6 NOISO -----------VPQQAEEGLT--LPQDSAV---PPATPVPQQAEEGLTLPQDSAVPPATL CAVPO66_3_PE3 NOISO ------------------------------------------------------------ FELCAGS_2169_PE3 NOISO -------------------------------XX---XXXX-XXX-X-------------- GORGO7_48_PE11 ENSGGOG00000000831 SAPKPVAAATLVPQEAEEGLT--LPQDSAT---TPPLPLQDTDLS----SAPKPVAAATL HS7_PE1372 NOISO SAPKPVAAATIVSQQAEEGLT--LPQDSAM---TPPLPLQDTDLS----SAPKPVAAATP LOXAF63_14_PE6 ENSLAFG00000007691 ----------------------------------------------SLTLHRESVSMATP MONDO6_282_PE18 ENSMODG00000010591 QTVDLESIATMISQTIEEAE--------------D----------------IEPIATMTS MONDO6_282_PE19 ISOFORMIN QTVDLESIATMISQTIEEAE--------------D----------------IEPIATMTS MOUSE11_PE263 NOISO SDQEREVAA-------------------------------------------------TL PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO -SPEPQPEEDLMASLPLEDANLPLVQGSATEASPEPQPEASASK-ASPEPQPEEVDLMAS PROCA10738_PE1 NOISO --------------------------------------------------------MATP PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO EEEE----------DSTAGGA--LSQAALG---PQLTPEAEEEEEDST-AGRAPAPRALS RAT14_PE922 NOISO SEPEPEVAA-------------------------------------------------TP MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO WPE-PATEAPECLEPATEAPEHSEPATEAPELPELTTEASECPELATEAPE--------- CALJA8_14_PE6 NOISO VPQQAEDSLTLPQ--GSAV--LPP-------------------L---------------- CAVPO66_3_PE3 NOISO ---QAKQGISLPQDPPE------------------------------------------- FELCAGS_2169_PE3 NOISO X---------XXXX--X-------------XXXXXXXXXXXX-XXX-------------- GORGO7_48_PE11 ENSGGOG00000000831 VPQQAEEGLTLPQ--DSAM--TPP-------------------L---------------- HS7_PE1372 NOISO VSQQAEEGLTLPQ--DSAM--TPP-------------------L---------------- LOXAF63_14_PE6 ENSLAFG00000007691 LPLQKAAALPLGQEPVAMA--TPQALQEEVGCPLGTAPAASEAALA-------------- MONDO6_282_PE18 ENSMODG00000010591 QT----IQETVGQEPIAIISHTIEEA---------------------------------- MONDO6_282_PE19 ISOFORMIN QT----IQETVGQEPIAIISHTIEEAVDLEHIVMMTSQTIEEAEDIEPIAVMTSQTIQET MOUSE11_PE263 NOISO GPQQAEEGVTIPQ--VAPV--ASP-------------------S---------------- PANTR7_50_PE19 NOISO ---QAEEGLTLPQ--DSAM--TPP-------------------L---------------- PIG18_51_PE9 NOISO LPL-QDAGLPLGQESASKA--TPEPQPEDAGLPLG-------QESATEASP--------- PROCA10738_PE1 NOISO LPLQRDAAFPLGQEPVAMATLQ--ALQAAAGCPLGRAPA----------AP--------- PTEVAGS_1659_PE2 NOISO ----------------------APG----------------------------------- RABIT10_47_PE33 NOISO QPCQERAGAALGPDPGTAE--GPPSLQDEAGH-------TSCPD---------------- RAT14_PE922 NOISO EPQQPEEGVTIPQ--VAPV--ALP-------------------S---------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO --HPEPATEALEHSE-----------------------------PAMEAPELPELIMESP CALJA8_14_PE6 NOISO ---------------PPQDTDLPSGPEPVAAAMLVPQQAEEGFTLPQDSAMTAPLPLQDT CAVPO66_3_PE3 NOISO ----------------------------------------------------PSPPLQDE FELCAGS_2169_PE3 NOISO --------XXXXXXX------------------------------XXXX-XXXXXXXXXX GORGO7_48_PE11 ENSGGOG00000000831 ---------------PLQDTDLSSAPKPVAAATLVPQQAEEGLTLPQDSAMTAPLPLQDT HS7_PE1372 NOISO ---------------PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDT LOXAF63_14_PE6 ENSLAFG00000007691 --------------------------------------------------------QPEV MONDO6_282_PE18 ENSMODG00000010591 ----------------TSQTIQAAGLKPIAV----------------------------- MONDO6_282_PE19 ISOFORMIN IDTIEEAVDVEPVATKTSQTIQAAGLKPIAV----------------------------- MOUSE11_PE263 NOISO ---------------LLQGLESTSDLESVVVGTPESQQDEGIATATQDTPVMAPPPLRGT PANTR7_50_PE19 NOISO ---------------PLQDTDLSSAPKPVAVATLVPQQAEEGLTLPQDSAMTAPLPLQDT PIG18_51_PE9 NOISO --EPQPEEKDLSAAPPLQDAVLPSVQASASKASP---------EPQPEVDLMASLPLQDT PROCA10738_PE1 NOISO --K-----AALAQ--------------------------------------------QEV PTEVAGS_1659_PE2 NOISO ---------------VLTEEDH-------------------------------------- RABIT10_47_PE33 NOISO -----P-----PQNTTAAGPDLPSGPGPVAAAPPVTPQALL------------------- RAT14_PE922 NOISO ---------------PLQGLDSTSDLESVVAGTMESWQDEGIATATQDMPVVAPPPLGGI MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO EVPEPATEA-PECPEPVSEAPECLEPATEA------------PECPEPA----------- CALJA8_14_PE6 NOISO GPTSVPELLAVATPQTLQAEGDCAPGTESVASMAQQEVGAALGPRPAPEE-NVALPRVPE CAVPO66_3_PE3 NOISO DSISSLETIAVATPRAPKAEAGCTPGSKAVASLAQQELGVASGQKPVPKEWAAAPLSDPE FELCAGS_2169_PE3 NOISO ---------------------XXXX----------------------------------- GORGO7_48_PE11 ENSGGOG00000000831 GPTSGPEPLAVATPQTLQAEAGWAPGTEPVATMAQQEVGAALGPRPAPEEKNAALPTVPE HS7_PE1372 NOISO GPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPE LOXAF63_14_PE6 ENSLAFG00000007691 GAALGLMSASELVAVAKPSTT----------------------------------EPEAE MONDO6_282_PE18 ENSMODG00000010591 ------------TSQALQETVE----LEPVAMKPSQTQKETIGLEPIAVAETPQT----- MONDO6_282_PE19 ISOFORMIN ------------TSQALQETVE----LEPVAMKPSQTQKETIGLEPIAVAETPQT----- MOUSE11_PE263 NOISO DSTSDPELIAPDTSQALQREAGHTPGTKPSVSEAHQELGVASGPRPVPKEGDAEPPPHSA PANTR7_50_PE19 NOISO GPTSGPEPLAVATPQSWQAEAGCAPGTEPVATMAQQEVGAALGPRPAPEEKNAALPTVPE PIG18_51_PE9 NOISO GLPLGQESASEASPEALQTDAGCTPGTGPMATTAQRKRSKTSGLRPEPEEKDPDHSGGAD PROCA10738_PE1 NOISO CVALGLMAASELMAVALSTEPEAE------------------------------------ PTEVAGS_1659_PE2 NOISO --TSAQGPVPAATHLPLQTDAGCALGAEPVTAAVQQEGGETLGLKPAPEK-DTGHAGDPE RABIT10_47_PE33 NOISO --PDCPTAGCPAGPEAVAASGLQAAGTKDTEPMTSQNQAVALRARPALENKSTAPPAGPA RAT14_PE922 NOISO ESTSDPELSAQDTPQALQREAGYTPGTKPSVSEAHQELGVALGPRPVPKEQDAKP-PHSE MATCH CONSENSUS ?????????????????????????????????????????????P??????????????

AILMEGL193092_1_PE26 NOISO TEALERSEP-------AMEPPECPESATE----ALAPERP-EPVSEAPERPEPVLEAPEC CALJA8_14_PE6 NOISO PVALDQVQQ-------DDTQPAAEAGTPWAALEDVGP----TL----------GLEAPHL CAVPO66_3_PE3 NOISO PVALNQAPQ-------DGPKPVAEAGELRPQREGTGP----NL----------DTKAPNR FELCAGS_2169_PE3 NOISO XXXXXXXX---------X--------XXX----XXX-----------------XX----- GORGO7_48_PE11 ENSGGOG00000000831 PAALDQVQQ-------DDPQPATEAGTPWAAQEDADS----TL----------GMEALSL HS7_PE1372 NOISO PAALDQVQQ-------DDPQPAAEAGTPWAAQEDADS----TL----------GMEALSL LOXAF63_14_PE6 ENSLAFG00000007691 PVALDQTQQ-------DGVGPALDLEPVPETVTPMASGKDADLTSEPVP----------- MONDO6_282_PE18 ENSMODG00000010591 LQEADRTQETPETLPARGQEVREEEKQEWPQDGESFPGA--------------------- MONDO6_282_PE19 ISOFORMIN LQEVGLEFSAVTCQTL--QEVSLKPIAVTPQ----TPQE--------------------- MOUSE11_PE263 NOISO PPASNQAQQ-------NGSEPGYKSDSFGAPEES-DS----TL----------STK---T PANTR7_50_PE19 NOISO PAALDQVQQ-------DDPQPAAEAGTPWAAQEDADS----TL----------GMEALSL PIG18_51_PE9 NOISO ALALDQAHP-------SGSEPAADARTPW--ALQGDVGPP-EPTTETPDRPEPTTEAPDL PROCA10738_PE1 NOISO PVALDQVQQ-------DA--PHLVAEAMT----SVASGKDTDLISEPVPRRQEAAEGPSG PTEVAGS_1659_PE2 NOISO PAALDQTQQ-------GGPDPAADARTPWASPIAIDA----LL----------GLEALDP RABIT10_47_PE33 NOISO LPVAAQAQQ-------DDPELAAEA-------EDASP----TS----------GMEAPGP RAT14_PE922 NOISO LPASDQAQQ-------NGSEPVVKNDNLGVPGEGSGP----TL----------STK---T MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO PEPATGPPRPAV-EATDPHKPASIGEEVEEGLLAPELG---------------------- CALJA8_14_PE6 NOISO PEPAS----------------GVGEEEVAEALSMPKWE---------------------- CAVPO66_3_PE3 NOISO PTAAL----------------GPAEEGA-----PGLPP---------------------- FELCAGS_2169_PE3 NOISO -------------------X-XXXXXXXXXXXXXXXXX---------------------- GORGO7_48_PE11 ENSGGOG00000000831 PEPAS----------------GAGE-EIAEALSRPGRE---------------------- HS7_PE1372 NOISO PEPAS----------------GAGE-EIAEALSRPGRE---------------------- LOXAF63_14_PE6 ENSLAFG00000007691 --------------------GRGKGQEAARGLSGPEPG---------------------- MONDO6_282_PE18 ENSMODG00000010591 -EPSF-PQREALPETWKLADGQDQGAEGQKGLVGEDEGARLDPLTEKSSVVISKGSENSL MONDO6_282_PE19 ISOFORMIN -EPGF-TL----------------------------------------------GS---- MOUSE11_PE263 NOISO SEPTS----------------CMGE-KVAANMSAPKQG---------------------- PANTR7_50_PE19 NOISO PEPAS----------------GAGEEIA-------------------------------- PIG18_51_PE9 NOISO PEP------------------DSSG---EETARAPEQG---------------------- PROCA10738_PE1 NOISO S----------------------------------EPG---------------------- PTEVAGS_1659_PE2 NOISO PEPTS----------------GGKE-----EPAGPDRG---------------------- RABIT10_47_PE33 NOISO PGPAF----------------DIGG-----AAAAPERE---------------------- RAT14_PE922 NOISO SEPLS----------------CMGE-KVTENLAAPKPG---------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO --------------TCPGACVCAGDGAETHLPQKEAPGGENQGAGGLESAPQGARKAPG- CALJA8_14_PE6 NOISO --------------ACLGARANTGDGDL---ASKETLEVENQQGGGLKPPARECEPGSAL CAVPO66_3_PE3 NOISO --------------AEKEAQVPTGDGAETCLPPEEAHGPKNQRARGPKAPTQGQGPRSAP FELCAGS_2169_PE3 NOISO --------------XX-XXXXXXXX-XXXXX------------XXXXX------------ GORGO7_48_PE11 ENSGGOG00000000831 --------------ACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSAL HS7_PE1372 NOISO --------------ACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSAL LOXAF63_14_PE6 ENSLAFG00000007691 --------------TGSG-LQHTDDGAG---------GLESQGDEGLPARTSGSGKALG- MONDO6_282_PE18 ENSMODG00000010591 SRDIDEERRPPVSLECSLQCPPSSREEEPDLGSEGSVGEQESSEQGSVSPPK-----MD- MONDO6_282_PE19 ISOFORMIN ---------KPITLEML-Q----------------ADRTQETPETLPARGQE-----MD- MOUSE11_PE263 NOISO --------------ACLEAH----DGVKTHSPQREALRSKNKRGRGTKSPGQGNGPKSAT PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO --------------ACLDGHVRGDDEAEPSLSPKEALGAEKQGGKVLE---------PV- PROCA10738_PE1 NOISO --------------TGIG-FQHTDDGAE---------GLESQRDEGLLVA-PGAGKAPG- PTEVAGS_1659_PE2 NOISO --------------ASLCAHLPTGEGAEPCSLPEEARRAENQGSGGLEPAPGVT------ RABIT10_47_PE33 NOISO --------------ESSGAHVHTSD------------EAEKRRRGGPKPLAQGHGGPRSA RAT14_PE922 NOISO --------------ACLEAH----DGAKTHSPQRQASRAKNKCGRGPKPPGQGKGSKSTA MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO ----DCGPEVHPAACPEVGHAWPQSPAEEGE-----ANPEPRSPVAVASEAGLGSCSEFP CALJA8_14_PE6 NOISO G-GTGEVPKVAPAACPEVGQARLLSPTREGRGPSVKSNLEPRLPSAVATEACLDSCPESS CAVPO66_3_PE3 NOISO R-GARGAPKTLCATYPEASQVQPQSPSREGRALGGKGTPASRLPTALVAEAQQGSCLGSP FELCAGS_2169_PE3 NOISO ---------XX--XX-XXXXXX-----------------------XXXXXXXXXXX---- GORGO7_48_PE11 ENSGGOG00000000831 G-GAGEVPEAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESS HS7_PE1372 NOISO G-GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESS LOXAF63_14_PE6 ENSLAFG00000007691 ----SSSWMVDLAISPELC-----------------QKREPGLPAAMASEAGLDSSPEPS MONDO6_282_PE18 ENSMODG00000010591 ---LVSGPADAISASDEIGAPGPTSGSRME----QIDVLGKE----FLAE---------- MONDO6_282_PE19 ISOFORMIN ---LVSGPADAISASDEIGAPGPTSGSRME----QIDVLGKE----FLAE---------- MOUSE11_PE263 NOISO SQGAVETCRAHSAARSEVSQPQLR---------SNEDTSGPRLPVAVSVQARLGSCPGSP PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO ----ALSPEASPAACLEAGPVRPPSPVEEGR-----ATLGPRLPRAAASEAGLGPGSESP PROCA10738_PE1 NOISO ----SSSLVVD----LALVPRWA--------------REQPGLLAAVVSEAELDSSSESL PTEVAGS_1659_PE2 NOISO -------GTAPGSGCPKLGLVQPPSPAEDGR-----VTPRPELPAAVAS--------ESP RABIT10_47_PE33 NOISO PPGAGET--------PGVSQGQPPSPAREGKRPSGKSTSRPKLPAAKLAEAGLGSCSKAP RAT14_PE922 NOISO SQGTTETFKAHSAARSETSQPQLM---------NSADSSGPRLPVAVSVQSKLGSCPGSP MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO PRSVP-RPGRRCPKEPGPTS------PAPSQQPEPMLGRGSGEWMQ-----------IAP CALJA8_14_PE6 NOISO AGAVS-RLDRGCPEAPAPTS------VPTFQQPEPVLGLGSVEQPQ-----------EAP CAVPO66_3_PE3 NOISO ARAMS-SPKKPGPS------------APSSPQQEPVPG--SGQRPL-----------ATP FELCAGS_2169_PE3 NOISO ----------------XXXX------XXXXXXXXXXXXXXXXXXXQ-----------VAP GORGO7_48_PE11 ENSGGOG00000000831 VGAVS-RLDRGCPDAPAPTS------APTSQQPEPVLGLGSVEQPH-----------KVP HS7_PE1372 NOISO VGAVS-SLDRGCPDAPAPTS------APTSQQPEPVLGLGSVEQPH-----------EVP LOXAF63_14_PE6 ENSLAFG00000007691 AGAVLGPSGRGCPGEPMSAT------TPPAPSWVPELGAGAGLQALQPHLGMEEQAQAAS MONDO6_282_PE18 ENSMODG00000010591 ---VEFNVEENCPEPAAQKPSLDEETPEPTGAPEPA------------------------ MONDO6_282_PE19 ISOFORMIN ---VEFNVEENCPEPAAQKPSLDEETPEPTGAPEPASRAKESRGSPGVPEGPQLDLARDA MOUSE11_PE263 NOISO ARATC-TLSRVYAEET-SRC------APPFQHLEPMLGLGSAEQPK-----------VTP PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO SRAVP-RLGGGCPKDPAPTL------PLPSRQPEPMLGRGSGGQAR-----------AAL PROCA10738_PE1 NOISO AGSVP-EPGKGCPGEPMPAT------TAPPTSWGREPGQGGVEEQA-----------QVA PTEVAGS_1659_PE2 NOISO SRAVP-RLGRGCPEEPALES------PPASQQLEPVHGPGGEEPAG-----------AAP RABIT10_47_PE33 NOISO ARAAS-RLGRGCPEEPAP--------ATPCRQPEPVLGLGRS---Q-----------VVP RAT14_PE922 NOISO ARATC-TLSRVYSEET-ARC------APPFQHPEPVLGLGSGEQPK-----------VTL MATCH CONSENSUS ??????????????????????????????????P?????????????????????????

AILMEGL193092_1_PE26 NOISO GSPSSSP-----P-QAP-K-S-P-A---RVLPSVPQDRLL-------------------- CALJA8_14_PE6 NOISO SVLGPHL-----L-QLP-E-N-L-A---KGLPSVPLDGLLG------------------- CAVPO66_3_PE3 NOISO SLLSPSP-----P-SHP-R-T-P-N---RGPPSEPRSRLLD------------------- FELCAGS_2169_PE3 NOISO GAPSSSP-----A-QSL-E-S-P-A---RGPPSMPQDRVL-------------------- GORGO7_48_PE11 ENSGGOG00000000831 SVLGTPL-----L-QPP-E-N-L-A---KGQPSTPADRLLG------------------- HS7_PE1372 NOISO SVLGTPL-----L-QPP-E-N-L-A---KGQPSTPVDRPLG------------------- LOXAF63_14_PE6 ENSLAFG00000007691 THLSHSP-----C-QSQ-G-P-Y-A---QELPTEVLDRSQLTEAHDRSPPAEDHDTSPPS MONDO6_282_PE18 ENSMODG00000010591 ------------------------------------------------------------ MONDO6_282_PE19 ISOFORMIN EQASFLGRAEGPSSPSPELTDLRFVPKPPKTSIVASVSPVGTEESHGPKLLVERAPSSLL MOUSE11_PE263 NOISO GILNL----------SP-D-N-S-A---GDLLTTSQNRFLD------------------- PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO RVLSPSP-----P-QPP-E-S-R-A---RHLASAPQDRTR-------------------- PROCA10738_PE1 NOISO SSSLSLP-----L-QFP-G-P-Y-A---QDLPTKAQDRSS-------------------- PTEVAGS_1659_PE2 NOISO GVFGPPA-----P-RP-------------------QDRLPG------------------- RABIT10_47_PE33 NOISO SVLSPTP-----P-QPP-E-D-P-A---RALPTAPQHRH--------------------- RAT14_PE922 NOISO GTLNL----------SS-E-N-S-A---GDLLTTPQNRLLD------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO ------------------------------------------------------------ CALJA8_14_PE6 NOISO ------------------------------------------------------------ CAVPO66_3_PE3 NOISO ------------------------------------------------------------ FELCAGS_2169_PE3 NOISO ------------------------------------------------------------ GORGO7_48_PE11 ENSGGOG00000000831 ------------------------------------------------------------ HS7_PE1372 NOISO ------------------------------------------------------------ LOXAF63_14_PE6 ENSLAFG00000007691 EAHDRSPPSEAQDTSPPSDDHDTSLPSDDHDTSLPSDDHDMSLPSEARETSPPSKAHGTS MONDO6_282_PE18 ENSMODG00000010591 ----RSPK-EPRG----AAEEKSALPRG----------------------KPPNAA---- MONDO6_282_PE19 ISOFORMIN SPTSRSPK-EPRG----AAEEKSALPRG----------------------KPPNAAGGQN MOUSE11_PE263 NOISO ------------------------------------------------------------ PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO ------------------------------------------------------------ PROCA10738_PE1 NOISO ------------------------------------------------------------ PTEVAGS_1659_PE2 NOISO ------------------------------------------------------------ RABIT10_47_PE33 NOISO ------------------------------------------------------------ RAT14_PE922 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO -------------------------------------------------------SPEPS CALJA8_14_PE6 NOISO ------------------------------------------------------PD--PS CAVPO66_3_PE3 NOISO ------------------------------------------------------PNP--S FELCAGS_2169_PE3 NOISO -------------------------------------------------------GPEPS GORGO7_48_PE11 ENSGGOG00000000831 ------------------------------------------------------PD--PS HS7_PE1372 NOISO ------------------------------------------------------PD--PS LOXAF63_14_PE6 ENSLAFG00000007691 PPSEAHDTSPPSHDHDTSPSSEDH-----D-TSPP-TEAWDTSPPSE-AHDTTSQYPDAS MONDO6_282_PE18 ENSMODG00000010591 ------------------------------------------------------------ MONDO6_282_PE19 ISOFORMIN TKLGKSQPRSAAPVAAFKEAQSPSSPLILMPSPVAPQAPPSPEASSNKGPPLPLAQKQEG MOUSE11_PE263 NOISO ------------------------------------------------------PDPAP- PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO -------------------------------------------------------SPEPP PROCA10738_PE1 NOISO -------------------------------------------------------HPDPF PTEVAGS_1659_PE2 NOISO --------------------------------------------------------PEPS RABIT10_47_PE33 NOISO ------------------------------------------------------------ RAT14_PE922 NOISO ------------------------------------------------------PDPDPS MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193092_1_PE26 NOISO ----VPGVPTEAAPYPMAPLTSCPCQGPREDSAE-----GKEPLGSLGLQPPRAGAQRAV CALJA8_14_PE6 NOISO ----VPGVLAEAALPPLDPPAPCLCQDLQEDSVE-----DKEPPGSRGRLSPQAGVQPAT CAVPO66_3_PE3 NOISO ----APGA-------------SRPHRGPRDDSME-----GVEPLASRGPPQPRVGAQRVT FELCAGS_2169_PE3 NOISO ----APRVPTEA------LLAPCPCQGPREDSVE-----GKEPSGSPGLQPPRAGAQRAA GORGO7_48_PE11 ENSGGOG00000000831 ----APGTLAEAALPPLEPPAPCLCQDPQEDSVE-----DEEPPGSLGLPPPQAGAQPAA HS7_PE1372 NOISO ----APGTLAGAALPPLEPPAPCLCQDPQEDSVE-----DEEPPGSLGLPPPQAGVQPAA LOXAF63_14_PE6 ENSLAFG00000007691 ----LPGFL------AGAAPIPCLCQGFREDCRD-----KGPP-GLPGLQQLGTDAPPAA MONDO6_282_PE18 ENSMODG00000010591 --------------------------DPDTAAARKVGSPRHRSPRGQGLASPRTPTPKA- MONDO6_282_PE19 ISOFORMIN GRVEGAITSSARAVSGNLPPSSLCPSDPDTAAARKVGSPRHRSPRGQGLASPRTPTPKA- MOUSE11_PE263 NOISO ------STLDRASQSSPGPPDPCLCPPPQKASEE-----EEKPPASRGPMPRAGAQGAAA PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO ----APGVPMESAPTPSGPPAPCSCQGPREDLGE-----GQEPLGSPGLPPPRARARRAA PROCA10738_PE1 NOISO ----LPAFSTGVARPHLAAPVPCLCQWPREDCRD-----KEPP-G---LQ-TLAQVPRAA PTEVAGS_1659_PE2 NOISO ----TPALLSGAAPPPTEPRVPCPCQCPQEDFVE-----EVE---TLGPPPPQAGTQQAM RABIT10_47_PE33 NOISO ----------------PGSLGPCLCQHPQD-SLD-----DEEPPDSPAPPTSRARAQRAT RAT14_PE922 NOISO ----APSALNRAFQSSPGPPDPCLCPTSQKDPVE-----EEKPSASHGLRSRAGVQGAAA MATCH CONSENSUS ???????????????????????????????????????????????G??????????A?

AILMEGL193092_1_PE26 NOISO AAFSGTTKPPGAGHRVSLPPHSPLLSPKMAPTGDTHAKDQAWRISPPCQVP--------- CALJA8_14_PE6 NOISO VAVSGTTQPLGIGLGVSLSPHSPLLSPKVAPT---DAKDLALQISLPCQVPPR----SGP CAVPO66_3_PE3 NOISO -AASGTTQPRGAGQHVGLAPQPPLLSPKAAPA---DAKEPASRTSPPCQVPPP----SGS FELCAGS_2169_PE3 NOISO AAFSGTTKPPGAGHRVGLPPHSPLLSPKTAPVGDTHAKDQAWRLSPPRQVP--------- GORGO7_48_PE11 ENSGGOG00000000831 AAVSGTTQPLGTGPRVSLSPHSPLLSPKVASM---DAKDLALQILPPCQVPPP----SGP HS7_PE1372 NOISO AAVSGTTQPLGTGPRVSLSPHSPLLSPKVASM---DAKDLALQILPPCQVPPP----SGP LOXAF63_14_PE6 ENSLAFG00000007691 AAVSGNPVPPGAGQQAGLSCPSPPLSPKAAPMGGPHAKALAAHICAPCQVPPC----SGL MONDO6_282_PE18 ENSMODG00000010591 VPYAKDQAPAGSPEVISNPCSRG-LWAGQAPLGGSGPQ-VVPKSPTPSQVPLGPVPGPGV MONDO6_282_PE19 ISOFORMIN VPYAKDQAPAGGESPLSSPQQQ---------------------------RCSGRLPAAGA MOUSE11_PE263 NOISO ITTSGSTKPPGARQRVSLSPHST-LNPKVAPT---DTKDLACIISSPCQVPPP----SGT PANTR7_50_PE19 NOISO ------------------------------------------------------------ PIG18_51_PE9 NOISO AAFSGTPNPPGAGQ-VGLPPQPLPLSPKAAPKGGNHAKDLASSISPPCQVPLG----SGP PROCA10738_PE1 NOISO AAISGNLVPPGAGQQAGLSCPLPHLSSKVTPMGGPCAKALSAHICDPCQVPLG----SGP PTEVAGS_1659_PE2 NOISO ATFSGTTNPPRAGQQVSLQPHPPLFSPEVAPVGDTYTKDPALQTPSPRQVPPG----SGP RABIT10_47_PE33 NOISO AAVSGTPRLPGPRQQAGLAARSPLPSPEAAPT---DAKDVASGPLPPRQVPPP----PGP RAT14_PE922 NOISO ITTSGSTKPLGARQRVSLSPHS--ANPKVTPT---DAKDPACIISSPCQVPPP----SGT MATCH CONSENSUS ???SG???P?G??????L???????????????????K????????P?QVP???????G?

AILMEGL193092_1_PE26 NOISO ---PSPR-GLLAAEQQDDQDSLEEDS-----------------------------PPRAP CALJA8_14_PE6 NOISO QSLTGPQ-GLSAPEQQEDEDSLEED------------------------------SPRVL CAVPO66_3_PE3 NOISO RGSRRPQ-GPPASEQQADEDSLEED------------------------------SPRAP FELCAGS_2169_PE3 NOISO ---PGPR-GLPAAEQQDDQDSLEEDS-----------------------------PPRGP GORGO7_48_PE11 ENSGGOG00000000831 QSPAGPQ-GLSAPEQQEDEDSLEED------------------------------SPRAL HS7_PE1372 NOISO QSPAGPQ-GLSAPEQQEDEDSLEED------------------------------SPRAL LOXAF63_14_PE6 ENSLAFG00000007691 CPPASPL-GLSAPEQQEDQDSLEEGKGEERGG-------PHTPGGVDSYSASSPDSFRAP MONDO6_282_PE18 ENSMODG00000010591 WAPTLSRAGLAATR-REEY-------------------------GIRDVAPPAGSRKSRE MONDO6_282_PE19 ISOFORMIN W-------------------------------------------------------GLFG MOUSE11_PE263 NOISO QNPSGPR-EFPALEQK-DEDSLEEDAQRAPGSGQRWESHGESSSELDEYLAPPPDAQRTP PANTR7_50_PE19 NOISO ----------------------EAH------------------------------SPRAL PIG18_51_PE9 NOISO RSPAGPR-GLPATEQQDDQDSVEEDS------------------------------PRAP PROCA10738_PE1 NOISO CPPASPL-GLPVPEQQEDQDSLEEDS------------------------------PRAP PTEVAGS_1659_PE2 NOISO WSLSSPR-DLQAAELQDDGDSLEEE------------------------------SPRG- RABIT10_47_PE33 NOISO SSLADAP-GAPAPEPQEDEDSPEED------------------------------SPRAP RAT14_PE922 NOISO QNPSGPR-GFPAHEQE-DEDSLEEASWTLSGETLEDGTGGPCTSKRPSYLAPPPDSQRAP MATCH CONSENSUS ???????????A?E???D?DS?EE?????????????????????????????????R??

AILMEGL193092_1_PE26 NOISO GSGQHSDSHGESS-AELEEQDLSGAQTAQCPAQAPAGGSSEETVAKAKQSRSEKKARKAM CALJA8_14_PE6 NOISO GSNQHSDSHGESS-AELDEQDILAPQTAQCPVQAPAG-GSEETIAKAKQSRSEKKARKAM CAVPO66_3_PE3 NOISO GSGQHSDSHGESS-AELDEQDVPAPH-AQRPAQAPTG-SSEETIAKAKQSRSEKKARKAM FELCAGS_2169_PE3 NOISO GSGXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXPRAGGREE-SLAAKQIFSVKKSRKAM GORGO7_48_PE11 ENSGGOG00000000831 GSGQHSDSHGESS-AELDEQDILAPQTVQCPAQAPAG-GSEETIAKAKQSRSEKKARKAM HS7_PE1372 NOISO GSGQHSDSHGESS-AELDEQDILAPQTVQCPAQAPAG-GSEETIAKAKQSRSEKKARKAM LOXAF63_14_PE6 ENSLAFG00000007691 GSGQHSDSHAESSAPEMEEQDLAAPRTSRCPPQAPTVGSSEETIAKAKQSRSEKKARKAM MONDO6_282_PE18 ENSMODG00000010591 GSRNDSESNGESL-PELEEPDNSDPRT--APPQLAHSVGSEETINKAKQSRSEKKARKAM MONDO6_282_PE19 ISOFORMIN GSRNDSESNGESL-PELEEPDNSDPRT--APPQLAHSVGSEETINKAKQSRSEKKARKAM MOUSE11_PE263 NOISO GSGQRSESHGESS-SELGEQDL-SPQKSQCPAQGPAG-SNEETIAKAKQSRSEKKARKAM PANTR7_50_PE19 NOISO GSGQHSDSHGESS-AELDEQDILAPQTVQCPAQASAG-GSEETIAKAKQSRSEKKARKAM PIG18_51_PE9 NOISO GSGQHSDSHGESS-AELEEQDLSGPQTAQCLAQAPAGGASEETVAKAKQSRSEKKARKAM PROCA10738_PE1 NOISO GSGQHSDSQAESSAPEMEEQDLAALRTARCPPQAPAVGSSEETIAKAKQSRSEKKARKAM PTEVAGS_1659_PE2 NOISO ----PSDSLEESS-AELEEQALSGPQATQCPAQALAG-RSEETMAKAKQSRSEKKARKAM RABIT10_47_PE33 NOISO GSGQHSDSHGESS-AEPDEQDVSAPQPAQCPAQAPAS-SSEDTIAKAKQSRSEKKARKAM RAT14_PE922 NOISO GSGQHSESHGESS-GELDEQDI-SPQKSQCPAQDPAG-SNEETTAKAKQSRSEKKARKAM MATCH *: *** * **:**** CONSENSUS GS???S?S??ESS??E??EQD???P?????P?Q??????SEET?AKAKQSRSEKKARKAM

AILMEGL193092_1_PE26 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAA CALJA8_14_PE6 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA CAVPO66_3_PE3 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA FELCAGS_2169_PE3 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAA GORGO7_48_PE11 ENSGGOG00000000831 SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA HS7_PE1372 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA LOXAF63_14_PE6 ENSLAFG00000007691 SKLGLRQIQGVTRITIQKSKNILFVISKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA MONDO6_282_PE18 ENSMODG00000010591 SKLGLRQIHGVTRITIRKSKNILFVISKPDVFKSPASDIYIVFGEAKIEDLSQQVHKAAA MONDO6_282_PE19 ISOFORMIN SKLGLRQIHGVTRITIRKSKNILFVISKPDVFKSPASDIYIVFGEAKIEDLSQQVHKAAA MOUSE11_PE263 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA PANTR7_50_PE19 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA PIG18_51_PE9 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAA PROCA10738_PE1 NOISO SKLGLRQIQGVTRITIQKSKNILFVISKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA PTEVAGS_1659_PE2 NOISO SKLGLRQIHGVTRIAIQKAKDILFVITKPDVFKSPASDTYVVFGEAKIEDLSQQAHRAAA RABIT10_47_PE33 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA RAT14_PE922 NOISO SKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAA MATCH ********:*****:*:*:*:*****:*********** *:*************.*:*** CONSENSUS SKLGLRQIQGVTRITIQKSKNILFVI?KPDVFKSPASDTYVVFGEAKIEDLSQQVH?AAA

AILMEGL193092_1_PE26 NOISO EKFKVPTEPSALVPESAPGPLVRPECEEEEE----EEEEEEVDEAGLELRDIELVMAQAN CALJA8_14_PE6 NOISO EKFKVPSEPSALVPESAPRPRVRLECGPQSAPATSLLPQPQVDEAGLELRDIELVMAQAN CAVPO66_3_PE3 NOISO EKFKVPSESLALVPESAPGPQLRP----------------EVDESGLELRDIELVMAQAN FELCAGS_2169_PE3 NOISO EKFKVPTEPSALVPESTPGPLVRPECEEEEE----EEEEEEVDEAGLELRDIELVMAQAN GORGO7_48_PE11 ENSGGOG00000000831 EKFKVPSEPSALVPESAPRPRVRLECKEEEEE-----EEEEVDEAGLELRDIELVMAQAN HS7_PE1372 NOISO EKFKVPSEPSALVPESAPRPRVRLECKEEEEE-----EEEEVDEAGLELRDIELVMAQAN LOXAF63_14_PE6 ENSLAFG00000007691 EKFKVPAEPSASASESAPGLRATPECAVGCSRAQ-PRVAQQVDETGLELRDIELVMAQAN MONDO6_282_PE18 ENSMODG00000010591 EKFKVPAEPSPIITETVPGLGAKEES-----------DEEEVDETGLEVRDIELVMAQAN MONDO6_282_PE19 ISOFORMIN EKFKVPAEPSPIITETVPGLGAKEES-----------DEEEVDETGLEVRDIELVMAQAN MOUSE11_PE263 NOISO EKFKVPSEPSALVPELSPGPRVRPECEEQEE------EDEEVEEAGLEPRDIELVMAQAN PANTR7_50_PE19 NOISO EKFKMPSEPSALVPESAPRPRVRLECKEEEE------EEEEVDEAGLELRDIELVMAQAN PIG18_51_PE9 NOISO EKFKVPSEPSPLVPESAPGPRVRPECEEEEE-----EEEEEVDEAGLELRDIELVMAQAN PROCA10738_PE1 NOISO EKFKVPAEPSARTSESAPGVQVTPECQEEE-------EEEAVDETGLELRDIELVMAQAN PTEVAGS_1659_PE2 NOISO EKFKVPAEPSTLGPESTPGPRVRLGCEENRE------EDEEVDEAGLELRDIELVMAQAN RABIT10_47_PE33 NOISO EKFKVPSEPSALVPESLPGPRVRPECSGRYH-----LVPPQVDEAGLELRDIELVMAQAN RAT14_PE922 NOISO EKFKVPSESSALVPELAPGPRVRPECEEQEE------EEEEVEEAGLEPRDIELVMAQAN MATCH ****:*:*. . .* * *:*:*** *********** CONSENSUS EKFKVP?EPS????E??P??????EC???????????????VDE?GLE?RDIELVMAQAN

AILMEGL193092_1_PE26 NOISO VSRARAVRALRDNQSDIVNAIMELTM CALJA8_14_PE6 NOISO VSRAKAVRALRDNHSDIVNAIMELTM CAVPO66_3_PE3 NOISO VSRAKAVRALRDNHSDIVNAIMELTM FELCAGS_2169_PE3 NOISO VSRARAVRALRDNQSDIVNAIMELTM GORGO7_48_PE11 ENSGGOG00000000831 VSRAKAVRALRDNHSDIVNAIM---- HS7_PE1372 NOISO VSRAKAVRALRDNHSDIVNAIMELTM LOXAF63_14_PE6 ENSLAFG00000007691 VSRAKAVRALRDNHSDIVNAIMELTM MONDO6_282_PE18 ENSMODG00000010591 VSRAKAVRALRHNNNDIVNAIMELTM MONDO6_282_PE19 ISOFORMIN VSRAKAVRALRHNNNDIVNAIMELTM MOUSE11_PE263 NOISO VTRAKAVRALKDNHSDIVNAIMELTM PANTR7_50_PE19 NOISO VSRAKAVRALRDNHSDIVNAIMELTM PIG18_51_PE9 NOISO VSRAKAVRALRDNQSDIVNAIMELTM PROCA10738_PE1 NOISO VSRAKAVRALRDNHSDIVNAIMELTM PTEVAGS_1659_PE2 NOISO VSRAKAVRALRDNQSDIVNAIMELTM RABIT10_47_PE33 NOISO VSRAKAVRALRDNHSDIVNAIMELTM RAT14_PE922 NOISO VSRAKAVRALKDNHSDIVNAIMELTM MATCH *:**:*****:.*:.******* CONSENSUS VSRAKAVRALRDN?SDIVNAIMELTM


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