Alignment of the gene Family HOG000115694 of HOGENOM

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Isoforms are ON
AILMEGL192563_1_1_PE11 NOISO -DARWPAGREDSIGLTLPGLT-LPGRAMFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE ANOCA505_PE4 NOISO -------------------------------------------------DRGQPCQACGE BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO ---------------------------MFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE CALJAX_49_PE3 ISOFORMIN ---------------EVEGRPLTSSLLPRLTGHWVYPRSLQPPEAED-PDRGQPCNSCRE CALJAX_49_PE4 ENSCJAG00000002694 ----------------------------FVWGSRRRMGSHPPPEAED-PDRGQPCNSCRE CANFAX_43_PE43 NOISO --------------MTLPGLT-LPGRAMFARGSRRRRSGRAPPELED-PDRGQPCNSCRE CAVPO132_3_PE22 NOISO ---QTRGGLADSIRLTRPGLT-LSGRTMFARGSRRRRSGRVPPEGDD-PDRGQPCNSCKE DANRE8_54_PE19 NOISO ---------------------------MFTRGSKKRRSNRST--EAEDPDRGQPCMRCGE DIPORGS_141_PE3 NOISO ---------------------------MFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE FUGRU226_PE49 NOISO ---------------------------MFLRGSKKRRSNRSP--EEEDPDRGQPCMRCGD GASACGROUPXII_17_PE4 NOISO ---------------------------MFTRGSKKRRSNRSK-QEEEDPDRGQPCMRCGD HORSEX_41_PE15 NOISO ---------------------------MFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE HSX_PE915 ENSG00000012211 ---------------------------MFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE LOXAF56_2_PE5 NOISO -DAPWPDRREDSISLTWS-GLTLPGRAMFVRGSRRRRSGRAAPPLHILPSSSQPSQ-S-- MACMUX_48_PE39 NOISO ---------------------------MFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE MICMUGS_117_PE3 NOISO ---------------------------MFARGSRRRRSGRVXXXXXXXXXXXXXX-XXXX MOUSEX_PE54 NOISO ---------------------------MFARGSRRRRSGRAPPEAED-PARGQPCNSCRE MOUSEX_PE55 NOISO ------------------------------------------------------------ MYOLUGS_1021_PE12 NOISO ------------------------------------------------------------ NEMVE_3395_PE187 NOISO ------------------------------------------MVAHDDDDGSKACNNCGD ORYLA7_22_PE45 NOISO ---------------------------MFLRGSKKRRSNRSPPQEEEDPDRGQPCMRCGD PANTRX_49_PE43 ENSPTRG00000021886 -----------------------------------------PPEAED-PDRGQPCNSCRE PIGX_44_PE10 NOISO PARRAVARRPQGFHSPGPAGLTLPGRAMFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE PONPYX_50_PE31 NOISO ---------------------------MFARGSRRRRSARAPPEAEH-PDRGQPCNSCRE PROCAGS_1353_PE2 NOISO ------------------------------------------------------------ PTEVAGS_92_PE3 NOISO ---------------------------MFARGSRRRRSGRAPPEAED-PDRGQPCNSCRE RATX_PE258 NOISO ---------------------------MFARGSRRRRSGRAPPEAED-PARGQPCNSCRE SPETRGS_404_PE2 NOISO ---------------------------MFARGSRRRRSGRLPPEAED-PDRGQPCNSCRE TETNG9_PE635 NOISO ---------------------------MFLRGSKKRRSTRSL--PDEDPDGGQPCTRCGD TRIAD_1217_PE269 NOISO ---------------------------------------------------GRPCLKCRQ TURTRGS_70_PE3 NOISO ---------------------------MFARGSRRRRSGRAPQEAED-PDRGQPCNSCRE MATCH CONSENSUS ?????????????????????????????????????????????????????PC??C??

AILMEGL192563_1_1_PE11 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHTVPV---DLERIMCQLISD-FQRHSISDDDSG ANOCA505_PE4 NOISO QCPGFLVHGWRK-ICQHCKCPREEHTVRMVPV---DLERMMCRLISD-FQRHSISDDDSG BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG CALJAX_49_PE3 ISOFORMIN QCPGFLLHGWRK-ICQHCKCPREEHAVHSVPV---DLERIMCRLISD-FQRHSISDDDSG CALJAX_49_PE4 ENSCJAG00000002694 QCPGFLLHGWRK-ICQHCKCPREEHAVHSVPV---DLERIMCRLISD-FQRHSISDDDSG CANFAX_43_PE43 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHSVPV---DLERIMCRLISD-FQRHSISDDDSG CAVPO132_3_PE22 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHTVPV---DLERIMCRLISD-FQRHSISDDDSG DANRE8_54_PE19 NOISO QCPGFRMHGWRK-ICVHCKCVREEHVVRSVPG---QLERMMMKLVSD-FQRHSISDDDSG DIPORGS_141_PE3 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---D-ERIMCRLISD-FQRHSISDDDSG FUGRU226_PE49 NOISO QCPGFRVHGWSPNICSRSSCAGRNRFNSAVPTLQGESQTMLTI-----TERGAIKLEGGG GASACGROUPXII_17_PE4 NOISO RCPGFRVHGWRK-ICVHCKCVREEHAVRSVPG---QLEKMMTKLVSD-FQRHSISDDDSG HORSEX_41_PE15 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG HSX_PE915 ENSG00000012211 QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG LOXAF56_2_PE5 NOISO SEPCPLLEGLRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FRRHSISDDDSG MACMUX_48_PE39 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG MICMUGS_117_PE3 NOISO XXXXXXXXXXXK-IRKLCKSPREERAVPAVPV---DLERIMCRLISD-FQRHSISDDDSG MOUSEX_PE54 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVRTVPV---DLERIMCRLISD-FQRHSISDDDSG MOUSEX_PE55 NOISO ----------------------------------------MCRLISD-FQRHSISDDDSG MYOLUGS_1021_PE12 NOISO ------------------------------------------------------------ NEMVE_3395_PE187 NOISO TCPGFSAHYWRK-ICRNCKCPREDHNIISDDARAGRNIYMAD---VH-RASSLASDDDSG ORYLA7_22_PE45 NOISO QCPGFRLHGWRK-ICVHCKCVREEHAVRSVPG---QLEKIMNKLVSD-FQRHSISDDDSG PANTRX_49_PE43 ENSPTRG00000021886 QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG PIGX_44_PE10 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG PONPYX_50_PE31 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG PROCAGS_1353_PE2 NOISO -----------K-ICQHCKCPREEHAVHTVPV---DLERVMCRLISD-FQHHSISDDDSR PTEVAGS_92_PE3 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHTVPV---DLERIMCRLISD-FQRHSISDDDSG RATX_PE258 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHTVPV---DLERIMCRLISD-FQRHSISDDDSG SPETRGS_404_PE2 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPV---DLERIMCRLISD-FQRHSISDDDSG TETNG9_PE635 NOISO QCPGFRVHGWRK-ICVHCKCVREEHAVHSVPG---QLEQMMTRLVSD-FQSHSISDDDSG TRIAD_1217_PE269 NOISO KCPGFCHHSWRK-ICRHCKCSKSEHDILADDH-----ERFVEKMIFEYYKVNGLSDFNIN TURTRGS_70_PE3 NOISO QCPGFLLHGWRK-ICQHCKCPREEHAVHAVPM---DLERIMCRLISD-FQRHSISDDDSG MATCH CONSENSUS ?CPGF??H?WRK?IC?HCKC?REEH?V??VP??????E??M??L?SD?FQRHSISDDDSG

AILMEGL192563_1_1_PE11 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT ANOCA505_PE4 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGERYRIRQLLHQLPPHDSEAQYCS BOVIN22_40_PE2 NOISO -------WEPSPQDVGMVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCN BOVINX_57_PE7 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEVQYCT CALJAX_49_PE3 ISOFORMIN CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT CALJAX_49_PE4 ENSCJAG00000002694 CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT CANFAX_43_PE43 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLYQLPPHDSEAQYCT CAVPO132_3_PE22 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT DANRE8_54_PE19 NOISO CASEEYAWVPPGIKPEQVYQYYSCIPEDKVPYVNSPGERYRIKQLLHQLPAHDSEPQYCN DIPORGS_141_PE3 NOISO CASEEYAWVPPGLKPEQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX FUGRU226_PE49 NOISO --GQMGLLLPAEGEAEQFPSXLQLPPGGRVPYVNSPGERYRIKQLLHQLPAHDSEPHYCN GASACGROUPXII_17_PE4 NOISO CASEEYAWVPPGLKPEQVYQYFSCLPEDRVPYVNSSGERYRIKQLLHQLPAHDSESQYCN HORSEX_41_PE15 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT HSX_PE915 ENSG00000012211 CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT LOXAF56_2_PE5 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYINSSGEKYRIKQLLHQLPPHDSEAQYCT MACMUX_48_PE39 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT MICMUGS_117_PE3 NOISO CASEE-GWVPRGPKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEXXXXX MOUSEX_PE54 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT MOUSEX_PE55 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT MYOLUGS_1021_PE12 NOISO -----------------VYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPLDSEAQYCT NEMVE_3395_PE187 NOISO CALDEYAWVPPGLGPEQVHSYMNALPEEKVPYVDSIGERYRNRQIILQLPPHDNEARFCN ORYLA7_22_PE45 NOISO CASEEYAWVPPGLKPEQVYQYFSCLPEDRVPYVNSPGERYRIKQLLHQLPAHDSEPQYCN PANTRX_49_PE43 ENSPTRG00000021886 CASEEYAWVPPGLKPE-----------QKVPYVNSPGEK-TIKQLLHQLPPHDSEAQYCT PIGX_44_PE10 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEVQYCT PONPYX_50_PE31 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAHYCT PROCAGS_1353_PE2 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSSGEKYRIKQLLHQLPPHDSEAQYCT PTEVAGS_92_PE3 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT RATX_PE258 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT SPETRGS_404_PE2 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT TETNG9_PE635 NOISO CASEEYAWVPPGLKPEQVYQYFSCLPEDSVPYVNSPGERNRIKQLLHQLPAHDSEPRYCN TRIAD_1217_PE269 NOISO PAIEEYAWTPPALSIRQIEAYFDCLPKENVPIIDSVGDRYRIQQLLYQHPAHDYDPKFCY TURTRGS_70_PE3 NOISO CASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCT MATCH CONSENSUS CASEEYAWVPPGLKPEQVYQ?FSCLPEDKVPYVNSPGE?YRIKQLLHQLP?HDSE??YC?

AILMEGL192563_1_1_PE11 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- ANOCA505_PE4 NOISO SLEEEEAKELKLFSQQRKRENLGRGTVRLFPVTITGAICE-------------------- BOVIN22_40_PE2 NOISO SLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQASFPAFDVAGPPAGSLQCL BOVINX_57_PE7 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- CALJAX_49_PE3 ISOFORMIN ALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICE-------------------- CALJAX_49_PE4 ENSCJAG00000002694 ALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICE-------------------- CANFAX_43_PE43 NOISO ALEEEEKKELRSFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- CAVPO132_3_PE22 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- DANRE8_54_PE19 NOISO SLDEEEKKELRLFSQQRKRENLGRGIVRLFPVTMTGAICQ-------------------- DIPORGS_141_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- FUGRU226_PE49 NOISO SLDEEEKKELRQFSQQRKRENLGRGVVRPFPVTMTGAICQ-------------------- GASACGROUPXII_17_PE4 NOISO TLDEEEKKELRLFSQQRKRENLGRGVVRLFPVTMTGAICQ-------------------- HORSEX_41_PE15 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- HSX_PE915 ENSG00000012211 ALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICE-------------------- LOXAF56_2_PE5 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- MACMUX_48_PE39 NOISO ALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICE-------------------- MICMUGS_117_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- MOUSEX_PE54 NOISO ALEEEEKKELRAFSQQRKRENLGRATVRIFPVTITGAICE-------------------- MOUSEX_PE55 NOISO ALEEEEKKELRAFSQQRKRENLGRATVRIFPVTITGAICE-------------------- MYOLUGS_1021_PE12 NOISO ALVEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- NEMVE_3395_PE187 NOISO GLSEEEKRELCFFVALRKRDSLGRGVVKQVPEMSEGYSCK-------------------- ORYLA7_22_PE45 NOISO SLDEDEKKELRLFSQQRKRENLGRGAVRLFPVTMAGAICQ-------------------- PANTRX_49_PE43 ENSPTRG00000021886 ALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICE-------------------- PIGX_44_PE10 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- PONPYX_50_PE31 NOISO ALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICE-------------------- PROCAGS_1353_PE2 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- PTEVAGS_92_PE3 NOISO ALEEEEKKELRAFSQKRKRENLGRGTVRIFPVTITGAICE-------------------- RATX_PE258 NOISO ALEEEEKKELRAFSQQRKRENLGRATVRIFPVTITGAICE-------------------- SPETRGS_404_PE2 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- TETNG9_PE635 NOISO SLDEQEKKELRQFSQQRKRENLGRGVVRPFPVTMTGAICQ-------------------- TRIAD_1217_PE269 NOISO RLSEEEKKKHRQFSATRKKDAFGQATVRTIGSRMNGHECAEVSY---------------- TURTRGS_70_PE3 NOISO ALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICE-------------------- MATCH CONSENSUS ?L?EEEKKELR?FSQQRKRENLGRG?VR?FPVT?TGAIC?????????????????????

AILMEGL192563_1_1_PE11 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCSTCRELLVDLIYFYHA ANOCA505_PE4 NOISO ------------QCGKQICGGDIAVFASRAG-HGACWHPQCFVCTTCRELLVDLIYFYQD BOVIN22_40_PE2 NOISO RDNETSAQFASCQCGGQINGGDIAVFASRAG-HGVSWHPPCFICTVCNELLVDLIYFYQD BOVINX_57_PE7 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCSTCRELLVDLIYFYHA CALJAX_49_PE3 ISOFORMIN ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFLCTTCRELLVDLIYFYHA CALJAX_49_PE4 ENSCJAG00000002694 ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFLCTTCRELLVDLIYFYHA CANFAX_43_PE43 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCCTCRELLVDLIYFYHA CAVPO132_3_PE22 NOISO ------------ECGKQIGGGDIAVFASRAG-LGTCWHPQCFVCTTCRELLVDLIYFYHA DANRE8_54_PE19 NOISO ------------QCGRQICGGDIAVFASRAG-HGSCWHPQCFQCASCNELLVDLIYFYQD DIPORGS_141_PE3 NOISO ------------XCGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCRELLVDLIYFYHA FUGRU226_PE49 NOISO ------------QCGRQICGGDIAVFASRAG-HGSCWHPQCFQCVSCSELLVDLIYFYQD GASACGROUPXII_17_PE4 NOISO ------------QCEKQIRGGDIAVFASRAE-QSSCWHPQCFQCATCSELLVDLIYFFQE HORSEX_41_PE15 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCSTCRELLVDLIYFYHA HSX_PE915 ENSG00000012211 ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCQELLVDLIYFYHV LOXAF56_2_PE5 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCRELLVDLIYFYHA MACMUX_48_PE39 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCRELLVDLIYFYHA MICMUGS_117_PE3 NOISO ------------XCGKQIGGGDIAVFASRAG-LGTSWHPQCFVCTTCRELLVDLIYFYHA MOUSEX_PE54 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCQELLVDLIYFYHA MOUSEX_PE55 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCQELLVDLIYFYHA MYOLUGS_1021_PE12 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCSTCRELLVDLIYFYHA NEMVE_3395_PE187 NOISO ------------ECGECVTAGSMAVYASRAG-QHTCWHASCFICTTCKELLVDLIYFYKD ORYLA7_22_PE45 NOISO ------------QCGRQICGGDIAVFASRAG-QGSCWHPQCFQCSSCSELLVDLIYFYQD PANTRX_49_PE43 ENSPTRG00000021886 ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCQELLVDLIYFYHA PIGX_44_PE10 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCSTCRELLVDLIYFYHA PONPYX_50_PE31 NOISO ------------EL---------------------------------------------- PROCAGS_1353_PE2 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCATCQELLVDLIYFYHA PTEVAGS_92_PE3 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCSTCRELLVDLIYFYHA RATX_PE258 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCQELLVDLIYFYHA SPETRGS_404_PE2 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCTTCRELLVDLIYFYHA TETNG9_PE635 NOISO ------------QCGRQICGGDMAVFASRAG-PGACWHPQCFQCVSCSQLLVDLIYFHQD TRIAD_1217_PE269 NOISO ---------ATPLCGEQLNHGELGLFASHAVPENLVWHPECFICCVCENGLVDLIYYYKD TURTRGS_70_PE3 NOISO ------------ECGKQIGGGDIAVFASRAG-LGACWHPQCFVCSTCRELLVDLIYFYHA MATCH CONSENSUS ?????????????CG?QI?GGDIAVFASRAG??G?CWHPQCF?C??C?ELLVDLIYFY??

AILMEGL192563_1_1_PE11 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR ANOCA505_PE4 NOISO GKIYCGRHHAERLKPRCEACDEIIFADECTEAEGRHWHMRHFCCFECEEALGG-QRYIMR BOVIN22_40_PE2 NOISO GKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGG-QRYIMK BOVINX_57_PE7 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG-QRYVMR CALJAX_49_PE3 ISOFORMIN GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG-QRYVMR CALJAX_49_PE4 ENSCJAG00000002694 GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG-QRYVMR CANFAX_43_PE43 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR CAVPO132_3_PE22 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR DANRE8_54_PE19 NOISO GHIYCGRHHAEHIKPRCQACDEIIFADECTEAEGRHWHMKHFCCFECEAALGG-QRYIMR DIPORGS_141_PE3 NOISO GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR FUGRU226_PE49 NOISO GQMYCGRHHAERLKPRCQACDEIILAHECTEAEGRYWHMKHFCCFECEAALGG-QRYIMG GASACGROUPXII_17_PE4 NOISO GQIYCGRHHAERLKPRCQACDEIILADECTEAEGRHWHMKHFCCFECEAALGG-QRYIMR HORSEX_41_PE15 NOISO GKVYCGRHHAERLRPRCQACDEIIFSAECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR HSX_PE915 ENSG00000012211 GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG-QRYVMR LOXAF56_2_PE5 NOISO GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR MACMUX_48_PE39 NOISO GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG-QRYVMR MICMUGS_117_PE3 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGQHWHMGHFCCFECEASLGG-QHYVMH MOUSEX_PE54 NOISO GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR MOUSEX_PE55 NOISO GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR MYOLUGS_1021_PE12 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR NEMVE_3395_PE187 NOISO SKVYCGRHHAETLKPRCAACDEIIFAEQCTEAEDSCWHVQHFCCFECDCPLGG-MRYVMR ORYLA7_22_PE45 NOISO GQIYCGRHHAERLKPRCQACDEIILADECTEAEGRYWHMKHFCCFDCEAALGG-QRYIMR PANTRX_49_PE43 ENSPTRG00000021886 GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG-QRYVMR PIGX_44_PE10 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR PONPYX_50_PE31 NOISO ------------------------------------------------------------ PROCAGS_1353_PE2 NOISO GKVYCGRHHAEYLRPRCQACDEIIFSPECTEAEGQHWHMGHFCCFECEASLGG-QRYVMR PTEVAGS_92_PE3 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR RATX_PE258 NOISO GKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR SPETRGS_404_PE2 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR TETNG9_PE635 NOISO GQIYCGRHHAERLKPRCQACDEIILAHECTEAEGRYWHMTHFCCFECEAALGG-QRYIMR TRIAD_1217_PE269 NOISO GEVYCGRHHADSVKPRCNACDEIIFTEECIQAHGRTWHTDHFVCYECECRLGSRNQYIMR TURTRGS_70_PE3 NOISO GKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGG-QRYVMR MATCH CONSENSUS G??YCGRHHAE?L?PRCQACDEIIF??ECTEAEGRHWHM?HFCCFECEA?LGG?QRY?MR

AILMEGL192563_1_1_PE11 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF ANOCA505_PE4 NOISO QSRPYCCRCYESLYAEYCDACGEHIGIDQGQMTYEGQHWHATDACFCCSRCHQPLLGKPF BOVIN22_40_PE2 NOISO EGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPF BOVINX_57_PE7 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASERCFCCSRCGRALLGRPF CALJAX_49_PE3 ISOFORMIN QSRPHCCTCYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASERCFCCSRCGRALLGRPF CALJAX_49_PE4 ENSCJAG00000002694 QSRPHCCTCYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASERCFCCSRCGRALLGRPF CANFAX_43_PE43 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF CAVPO132_3_PE22 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDHCFCCSRCGRALLGRPF DANRE8_54_PE19 NOISO ESRPYCCRCYESLYAEYCDTCGEHIGIDQGQMTYEGQHWHASEQCFCCACCRLPLLGRPF DIPORGS_141_PE3 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSSCGRALLGRPF FUGRU226_PE49 NOISO ESRPYCCSCYESLYAEYCDTCGEHIGIDQGQMTYEGQHWHAVESCFCCARCRLPLLGRPF GASACGROUPXII_17_PE4 NOISO ESRPYCCSCYESQYAEYCDTCGEHIGIDQGQMTYEGQHWHAVESCFCCARCHLPLLGRPF HORSEX_41_PE15 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF HSX_PE915 ENSG00000012211 QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF LOXAF56_2_PE5 NOISO QSRPHCCTCYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSCCGRALLGLPF MACMUX_48_PE39 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF MICMUGS_117_PE3 NOISO QSRPHCCTCYEARHAEYCDGCGEHIGLDQGQMAYQGQHWHASDGCFCCSHCGCALLGRPF MOUSEX_PE54 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCSRPLLGRPF MOUSEX_PE55 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCSRPLLGRPF MYOLUGS_1021_PE12 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGHPF NEMVE_3395_PE187 NOISO DNKPYCCHCFESLYAEFCDSCGEPIEPDASQMAHNGQHWHATNECFSCCTCGKALLGLPF ORYLA7_22_PE45 NOISO ECRPYCCSCYQSLYAESCDTCGEHIGIDQGQMTYEGQHWHAVEACFCCARCRLPLLGRPF PANTRX_49_PE43 ENSPTRG00000021886 QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCILGGRALLGRPS PIGX_44_PE10 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF PONPYX_50_PE31 NOISO ---------------------------DQGQMAYE-QHWHASDRCFCCSRCGRALLGRPF PROCAGS_1353_PE2 NOISO QSRPHCYACYEALHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCRRALLGRPF PTEVAGS_92_PE3 NOISO QSRPHCCACYEARHAEYCDSCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF RATX_PE258 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF SPETRGS_404_PE2 NOISO QSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF TETNG9_PE635 NOISO ESRPYCCSCYESLYVEYCDTCGEHIGIDQGQMTYEGQRWHAAARCFCCARCRLPLLGRPF TRIAD_1217_PE269 NOISO DGQPYCCRCFESLYAVYCESCGEMIELNDGHMAHNDMHWHASDDCFSCSECNQSLLGKTF TURTRGS_70_PE3 NOISO QSRPHCC-CYEARHAEYCDGLGKHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPF MATCH : .:*::: :*** **.* .*** . CONSENSUS ?SRP?CC?CYE???AEYCD?CGEHIG?DQGQM?YEGQHWHA???CFCC??C???LLGRPF

AILMEGL192563_1_1_PE11 NOISO LPRRGLIFCSRACSLGSEPTAS---ATGRRSWSAG--T---------------------- ANOCA505_PE4 NOISO LPKQGQIFCSRACSLGEDPNASDSCDS---AFQSARSQDSRRAS---------------- BOVIN22_40_PE2 NOISO LPKQGQIFCSRACSAGED------------------------------------------ BOVINX_57_PE7 NOISO LPRRGLIFCSRACSLGSEPMAP---AHSRRSWSTS--T---------------------- CALJAX_49_PE3 ISOFORMIN LPRRGLIFCSRACSLGSEPTTP---GPGRRSWSAG--T---------------------- CALJAX_49_PE4 ENSCJAG00000002694 LPRRGLIFCSRACSLGSEPTTP---GPGRRSWSAG--T---------------------- CANFAX_43_PE43 NOISO LPRRGLIFCSRACSLGSEPTSSGTSGTGRQSWSAG--T---------------------- CAVPO132_3_PE22 NOISO LPLRGLIFCSRACSLGSEPTAP---RPGRRSWSSG--T---------------------- DANRE8_54_PE19 NOISO LPRGGLIFCSRSCSLGEDPENSDSCDS---ALQSKSATHKPLQSQQRSSTPRPQGGSSDI DIPORGS_141_PE3 NOISO LPRRGLIFCSRACSLGSETTAP---GSGRRSWSAG--T---------------------- FUGRU226_PE49 NOISO LPRGGLIFCSRACSLGGAEPTAPAP-P---RW---------------------------- GASACGROUPXII_17_PE4 NOISO LPRGGLIFCSRPCSLGEDPNNSDSCDS---ALQSKPPQHRRCESAKKHQQPQ--CGSPL- HORSEX_41_PE15 NOISO LPRRGLIFCSRACSLGSEPTAP---GPGRRSWSAG--T---------------------- HSX_PE915 ENSG00000012211 LPRRGLIFCSRACSLGSEPTAP---GPSRRSWSAG--P---------------------- LOXAF56_2_PE5 NOISO LPRCGLIFCSRACSLRSEPTAP---GPGRRSWSAG--T---------------------- MACMUX_48_PE39 NOISO LPRRGLIFCSRACSLGSEPTAP---GPGRRSWSAG--T---------------------- MICMUGS_117_PE3 NOISO LPRRGLIFCSRACSLGSEPTTL---GPGRCSWSSG--T---------------------- MOUSEX_PE54 NOISO LPRRGLIFCSRACSLGSETTAP---GPGRRSWSAG--T---------------------- MOUSEX_PE55 NOISO LPRRGLIFCSRACSLGSETTAP---GPGRRSWSAG--T---------------------- MYOLUGS_1021_PE12 NOISO LPRRGLIFCSRACSLGSEPTDS---GPGRRSWSAG--T---------------------- NEMVE_3395_PE187 NOISO LPKSGEIYCSPDCSNGIPP----------------------------------------- ORYLA7_22_PE45 NOISO LPRKGLIFCSRSCSLGDDPNKSPPHNR---RWA---------------GHHKLQCGSPLQ PANTRX_49_PE43 ENSPTRG00000021886 P-ARGLI-CSR------------------------------------------------- PIGX_44_PE10 NOISO LPRRGLIFCSRACSLGSEPTAP---GPGRRSWSAG--T---------------------- PONPYX_50_PE31 NOISO LPRRGLIFCSRACSLGSEPTAP---GRGRRSWSAG--T---------------------- PROCAGS_1353_PE2 NOISO LPRGGLIFCSRACSLGQESTVP---GPGRCSWSAG--T---------------------- PTEVAGS_92_PE3 NOISO LPRRGLIFCSRACSLGSETTTQ---GPGRRSWSTS--T---------------------- RATX_PE258 NOISO LPRRGLIFCSRACSLGSETTTA---GPGRRSWSAG--T---------------------- SPETRGS_404_PE2 NOISO LPRRGLIFCSRACSLGSEPTAP---GPGRRSWSGGGGT---------------------- TETNG9_PE635 NOISO LPRRGLIFCSRACSLGEDPDNSDSCDS---ALQSRPPPHRRSAAAE-----KPQCGSPL- TRIAD_1217_PE269 NOISO LPKHGKLYCSVAC----------------------------------------------- TURTRGS_70_PE3 NOISO LPRRGLIFCSRACSLGSELTAP---GPGRRSWSAG--T---------------------- MATCH * : ** CONSENSUS LPR?GLIFCSRACSLG????????????????????????????????????????????

AILMEGL192563_1_1_PE11 NOISO ---------------------------------------VSAPLAAST-ASFSA-AEE-A ANOCA505_PE4 NOISO ------------------------------------------------------------ BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO ---------------------------------------VSTPLTAST-ASFSA-VEG-A CALJAX_49_PE3 ISOFORMIN ---------------------------------------VTAPLAAST-ASFSA-AEG-V CALJAX_49_PE4 ENSCJAG00000002694 ---------------------------------------VTAPLAAST-ASFSA-AEG-V CANFAX_43_PE43 NOISO ---------------------------------------VSAPLAASS-ASFSA-AEEET CAVPO132_3_PE22 NOISO ---------------------------------------VTAPLAAST-ASFTA-VEG-R DANRE8_54_PE19 NOISO SIQRTPAANGGQITLQTKGVHTSFPPLVNGDPPPYGRTSTPHPLPSAQLCPVANDRAGSL DIPORGS_141_PE3 NOISO ---------------------------------------VTAPLTGST-ASFPV-EEG-A FUGRU226_PE49 NOISO -----------------------------------GRGETAVRFSAA------------- GASACGROUPXII_17_PE4 NOISO -------------------------------QPPEGAGS---PVTPAKDCVR-------- HORSEX_41_PE15 NOISO ---------------------------------------VSAPLAAST-ASFSA-VEG-V HSX_PE915 ENSG00000012211 ---------------------------------------VTAPLAAST-ASFSA-VKG-A LOXAF56_2_PE5 NOISO ---------------------------------------VSTPLAAST-ASS-A-VEG-A MACMUX_48_PE39 NOISO ---------------------------------------VTAPLAAST-ASFSA-AEG-A MICMUGS_117_PE3 NOISO ---------------------------------------VTTPLTAST-ASFSA-AEG-A MOUSEX_PE54 NOISO ---------------------------------------VTTPLTTST-ASFSA-TEG-T MOUSEX_PE55 NOISO ---------------------------------------VTTPLTTST-ASFSA-TEG-T MYOLUGS_1021_PE12 NOISO ---------------------------------------VSSPLEAST-ASFSA-VEGP- NEMVE_3395_PE187 NOISO ------------------------------------------------------------ ORYLA7_22_PE45 NOISO PLE--------------------------------GARPSLTPTND--SIQFTEENRG-- PANTRX_49_PE43 ENSPTRG00000021886 ------------------------------------------------------------ PIGX_44_PE10 NOISO ---------------------------------------VSTPLAAST-ASFSA-VEG-A PONPYX_50_PE31 NOISO ---------------------------------------VTAPLAVST-ASFSA-VEG-A PROCAGS_1353_PE2 NOISO ---------------------------------------VSVPLRVST-ASFSA-VEA-S PTEVAGS_92_PE3 NOISO ---------------------------------------VSAPFAAST-ASFST-VEG-A RATX_PE258 NOISO ---------------------------------------VTTALTAST-ASFSA-TEV-T SPETRGS_404_PE2 NOISO ---------------------------------------VAARLATST-SSFPA-SEX-X TETNG9_PE635 NOISO -------------------------------QPPEGAK----------TCVFTAQ----- TRIAD_1217_PE269 NOISO ------------------------------------------------------------ TURTRGS_70_PE3 NOISO ---------------------------------------VSTPLTAST-ASFSA-VEG-V MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192563_1_1_PE11 NOISO SGPDNR-ELLHLFPVAGPEEPAHF------------LRGAPHRH---------------- ANOCA505_PE4 NOISO ------------------------------------------------------------ BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO SETTTKGTNTEAAPAADPEEPTHF------------LRGAPHRH---------------- CALJAX_49_PE3 ISOFORMIN LETTTKGTCTASEPAAGPEEPSHF------------LRGAPHRH---------------- CALJAX_49_PE4 ENSCJAG00000002694 LETTTKGTCTASEPAAGPEEPSHF------------LRGAPHRH---------------- CANFAX_43_PE43 NOISO AETATKGTSTEPGPVVGPEEPAHF------------LRGAPHRH---------------- CAVPO132_3_PE22 NOISO SETATKGTSTEATSAIGPEEPSRF------------LRGAPHRH---------------- DANRE8_54_PE19 NOISO SKDQSE-----TPSADGPYSALEFTVE--LNGYAEFGPFPPSCTSRGTSTVKDCGNIIES DIPORGS_141_PE3 NOISO SETATKGTSTEATPAVGHEEPPKF------------LRGAPHRH---------------- FUGRU226_PE49 NOISO ---ATR-----GFAIKGPLSAVFSPQNSNVNRVTS-PDAPPATA---------------- GASACGROUPXII_17_PE4 NOISO --DAVE-----NRGDDDTL-VSYFDLF--LYHL---HVLPPLAF---------------- HORSEX_41_PE15 NOISO SETATKGTSTEPAPAAGPEEPARF------------LRGAPHRH---------------- HSX_PE915 ENSG00000012211 SETTTKGTSTELAPATGPEEPSRF------------LRGAPHRH---------------- LOXAF56_2_PE5 NOISO SETATKGTSTKSAPAAGPEEPTRF------------LRGAPYRH---------------- MACMUX_48_PE39 NOISO SETTTKGTCTESAPATGPEEPSRF------------LRGAPHRH---------------- MICMUGS_117_PE3 NOISO SKTATKDTCTESPPAADPEEPSRF------------LREAPHRH---------------- MOUSEX_PE54 NOISO SETASKGTCTKAEPAAGPEEPSHF------------LRGAPHRH---------------- MOUSEX_PE55 NOISO SETASKGTCTKAEPAAGPEEPSHF------------LRGAPHRH---------------- MYOLUGS_1021_PE12 NOISO SETSTKGTSTEV--------------------------EPPHNH---------------- NEMVE_3395_PE187 NOISO ------------------------------------------------------------ ORYLA7_22_PE45 NOISO -----N-----GLGPSWPSD---I------P--HSFLASPPHKH---------------- PANTRX_49_PE43 ENSPTRG00000021886 ------------------------------------------------------------ PIGX_44_PE10 NOISO SETTTKGTSTEPASAAGPEEPARF------------LRGAPHRH---------------- PONPYX_50_PE31 NOISO SETTTKGTSTELAPAAGPEEPSRF------------LRGAPHRH---------------- PROCAGS_1353_PE2 NOISO SETATKGTSTESAHATGTEEPARF------------LRGVPHRH---------------- PTEVAGS_92_PE3 NOISO SETASKGTSTEPSPAAGPEEPTRF------------LRGAPHRH---------------- RATX_PE258 NOISO SE-ASKGTCTK-SPAAGPEEPSHF------------LRGAPHRH---------------- SPETRGS_404_PE2 NOISO XXXXXXXXXXXXXXXAGAEEPSPF------------TRGAPHRH---------------- TETNG9_PE635 NOISO --DRVH-----GSSTQLP-----F---------ETSGSFRPVYRSGAK-------RRFFM TRIAD_1217_PE269 NOISO ------------------------------------------------------------ TURTRGS_70_PE3 NOISO SETSTKGTSTEPAPAAGSEEPARF------------LRGAPHRH---------------- MATCH CONSENSUS ????????????????????????????????????????P???????????????????

AILMEGL192563_1_1_PE11 NOISO ----------SLPELG-LR-SPPEPPPGLPSQP----------EPSLEDG-AFGRQSTPR ANOCA505_PE4 NOISO ------------------------------------------------------------ BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO ----------HHDHHH-------------------------------------------- CALJAX_49_PE3 ISOFORMIN ----------SMPELG-LR-SAPELPPESPGQP----------NPRPDDS-AFGRQSTPR CALJAX_49_PE4 ENSCJAG00000002694 ----------SMPELG-LR-SAPELPPESPGQP----------NPRPDDS-AFGRQSTPR CANFAX_43_PE43 NOISO ----------SMPELG-LR-GPPEPPPGLPSQP----------DPPLEDG-AFGRQSTPR CAVPO132_3_PE22 NOISO ----------SMPELG-LR-SAPEPTLESPGQP----------DLCQEDN-VFGRHSTPR DANRE8_54_PE19 NOISO SCSGISSQLASFDDLNDSDSFPP-PPPPVFFDPSDSPDPLASVTEAEDLPAAPVRSSTAR DIPORGS_141_PE3 NOISO ----------SMPELG-LR-GPPEPPMETPGQP----------DQRPEDS-TFGRQSTQR FUGRU226_PE49 NOISO ------TALPPPLPVKSREARPQEPPSPTLRRP---------ADAPPDSPPPLTRSGTAR GASACGROUPXII_17_PE4 NOISO -------LSTGFPPQE----NPP-PLPPN--NPSVLPPPLPL------------KS---- HORSEX_41_PE15 NOISO ----------SMPELG-LR-SAPEPSPGPPGQP----------DQPPEDG-AFGRQSAPR HSX_PE915 ENSG00000012211 ----------SMPELG-LR-SVPEPPPESPGQP----------NLRPDDS-AFGRQSTPR LOXAF56_2_PE5 NOISO ----------SMPELG-LR-SAPEPPHQ----P----------DPRLED-NAFGRQSAPR MACMUX_48_PE39 NOISO ----------SMPELG-LR-SAPEPPPESPGQP----------NLRPDDS-AFGRQSTPR MICMUGS_117_PE3 NOISO ----------SMPELG-LR-STTEPPSESPGQP----------IPRPDDS-AFGRQSTPR MOUSEX_PE54 NOISO ----------SMPELG-LR-SAPEPPTESPGHP----------APHPDDN-AFGRQSTPR MOUSEX_PE55 NOISO ----------SMPELG-LR-SAPEPPTESPGHP----------APHPDDN-AFGRQSTPR MYOLUGS_1021_PE12 NOISO ----------NIPELG-IC-SAPEPPPGTPGHL----------DPED---DSFSRQSAPR NEMVE_3395_PE187 NOISO ------------------------------------------------------------ ORYLA7_22_PE45 NOISO ---------FLVNPLISLDSPPRDSPPPTLSQP---------EDRPHESPPPLACSGTAR PANTRX_49_PE43 ENSPTRG00000021886 ------------------------------------------------------------ PIGX_44_PE10 NOISO ----------SMPELG-LR-SAPEPPSGPPGQP----------DPHPEDG-AFGRQSAPR PONPYX_50_PE31 NOISO ----------SMPELG-LR-SAPEPPPESPRQP----------NLRPDDS-AFSRQSTPR PROCAGS_1353_PE2 NOISO ----------SMPELG-LR-SAPEPPRRP--------------DRCLED-GAFGHQSTPR PTEVAGS_92_PE3 NOISO ----------SMPELG-LR-CASEPPTGTPSQP----------A--PEDG-AFSRQSAPR RATX_PE258 NOISO ----------SMPELG-LR-SAPEPPTESPGHP----------ALHPDDNTTFGRQSTPR SPETRGS_404_PE2 NOISO ----------SMPELG-LR-NAPEQPLESPEQP----------DLRPDDS-AFGRQSTPR TETNG9_PE635 NOISO RCSGVTSSD----------------APPA--ATSPLPPPLPVKSRDWDSPPGLTRSSTAR TRIAD_1217_PE269 NOISO ------------------------------------------------------------ TURTRGS_70_PE3 NOISO ----------SMPELG-LR-SVPEPPSGPAGQP----------DPRPEDG-AFGRQSTPR MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192563_1_1_PE11 NOISO VSFRDPLVSDGGPRRT----LSAPPAQR-RR--------------------------PRS ANOCA505_PE4 NOISO ------------------------------------------------------------ BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO ------------------------------------------------------------ CALJAX_49_PE3 ISOFORMIN VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS CALJAX_49_PE4 ENSCJAG00000002694 VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS CANFAX_43_PE43 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS CAVPO132_3_PE22 NOISO VSFTEKVISHGSPYR--------------------------------------------- DANRE8_54_PE19 NOISO VSFREPISCSYSVEENEWEDEDQPEMQRRDRDEDEQEEDGEEAEGSLGHRLRICSQVPSR DIPORGS_141_PE3 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS FUGRU226_PE49 NOISO VSFREPISSCYSLDEDEGDKEEELQQEGLRRGWH--------Q-----------SGIPKD GASACGROUPXII_17_PE4 NOISO ---RDPMP----------PDSPQPDLPQLA------------------------ERSPAS HORSEX_41_PE15 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS HSX_PE915 ENSG00000012211 VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS LOXAF56_2_PE5 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS MACMUX_48_PE39 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS MICMUGS_117_PE3 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS MOUSEX_PE54 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS MOUSEX_PE55 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS MYOLUGS_1021_PE12 NOISO VSFREPLVSDGGPRRT----LSAPPAQR-RR--------------------------PRS NEMVE_3395_PE187 NOISO ------------------------------------------------------------ ORYLA7_22_PE45 NOISO VSFREPISSSYSVEEDGDEDSALR------------------------------------ PANTRX_49_PE43 ENSPTRG00000021886 ------------------------------------------------------------ PIGX_44_PE10 NOISO VSFRDPLVSDGGPRRT----LSAPPAQR-RR--------------------------PRS PONPYX_50_PE31 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-CR--------------------------PRS PROCAGS_1353_PE2 NOISO VSFHDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS PTEVAGS_92_PE3 NOISO VSFRDPLVSEGDLRRT----LSVPPAQNRSR--------------------------PRS RATX_PE258 NOISO VSFRDPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS SPETRGS_404_PE2 NOISO VSFREPLVSEGGPRRT----LSAPPAQR-RR--------------------------PRS TETNG9_PE635 NOISO VSFREPISSSYSLH---WRRSSVPTDQALHTRA--------------------------- TRIAD_1217_PE269 NOISO ------------------------------------------------------------ TURTRGS_70_PE3 NOISO VSFRDPLVSEGGPRRS----LSVPPAQR-RR--------------------------PRS MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192563_1_1_PE11 NOISO PPPRAPTHRRRHHHHHH---HH-----HHRRH-SGR------------------------ ANOCA505_PE4 NOISO ------------------------------------------------------------ BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO ------------------------HHHHHRCHFGRR------------------------ CALJAX_49_PE3 ISOFORMIN PPPRAPSRRRHRHNHR-----H-----HHHRNPSRR------------------------ CALJAX_49_PE4 ENSCJAG00000002694 PPPRAPN-----------------------RNPSRR------------------------ CANFAX_43_PE43 NOISO PPPRAPTHRRRSSRRR---HHH-----HHRRHSGRH------------------------ CAVPO132_3_PE22 NOISO ------------------------------------------------------------ DANRE8_54_PE19 NOISO MDLLDGSYHCNFRR--GSGGHHSSEKRYRRSRGSRSDRPRLETLDVERRRSSNNADGSRN DIPORGS_141_PE3 NOISO PPPRAPTRHHRHHRHHHHHH---------HHPSRRR------------------------ FUGRU226_PE49 NOISO --------------------PVLHRRTERRHRSSQSTRPRLDSLERRGEKDG-------- GASACGROUPXII_17_PE4 NOISO PPPLS------------------------------------------RSGTARFSHHSHF HORSEX_41_PE15 NOISO PPPRAPTHRHRRRHHHH---------HRHHRHSGRC------------------------ HSX_PE915 ENSG00000012211 PPPRAPSRRRHHHHN----HHH-----HHNRHPSRR------------------------ LOXAF56_2_PE5 NOISO PPPL-----------------------------VRR------------------------ MACMUX_48_PE39 NOISO PPPRAPSRHRHRHNHHH--HHH-----HHHRHPSRR------------------------ MICMUGS_117_PE3 NOISO PPPRAPNHRHRRRRHH----------HHHHHHPSRR------------------------ MOUSEX_PE54 NOISO PPPRTPSCHHHHHHRRRRQRHRRRGSHHHHHHPGRH------------------------ MOUSEX_PE55 NOISO PPPRTPSCHHHHHHRRRRQRHRRRGSHHHHHHPGRH------------------------ MYOLUGS_1021_PE12 NOISO PPPKAPTRRRHHHH---------------RRRRSGR------------------------ NEMVE_3395_PE187 NOISO ------------------------------------------------------------ ORYLA7_22_PE45 NOISO ------------------------PGSDRRSRSSRRERPRLDALDWKGETERDGRGPSST PANTRX_49_PE43 ENSPTRG00000021886 ------------------------------------------------------------ PIGX_44_PE10 NOISO PPPRAPTRRRHRRHHHH--HHHHHHHHHHRRHSSRR------------------------ PONPYX_50_PE31 NOISO PPPRAPSRRRHRHNHH-----H-----HHHCHLSRR------------------------ PROCAGS_1353_PE2 NOISO TQHRTPRH-------------HCGQRHRRRRLPGRH------------------------ PTEVAGS_92_PE3 NOISO PPPRAPRRH-----------HH-----HRCRHSGRH------------------------ RATX_PE258 NOISO PPPRAPSCYHHHHRRRR--RRRRRGSHQHHHHPGRH------------------------ SPETRGS_404_PE2 NOISO PPPRAPSRRRHHH--------H-----HHHRHTGRR------------------------ TETNG9_PE635 NOISO ---------------------------ERRRRGSWSARPRPDAPE--GRGEE--QGAEAA TRIAD_1217_PE269 NOISO ------------------------------------------------------------ TURTRGS_70_PE3 NOISO PPPRGPIHRRHPHHH---------HHHHHRRHSGRR------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192563_1_1_PE11 NOISO HRHHRDLGSGSDSGSCSSSPSSPSSESSEEDGFFLGERIPLPPHLCRPGPAQDNATGTPK ANOCA505_PE4 NOISO ------------------------------------------------------------ BOVIN22_40_PE2 NOISO ------------------------------------------------------------ BOVINX_57_PE7 NOISO RHHQCDLGSGSDSGSCSSSPSSSSSESSEEDGYFLGERIPLSPHLCRPVLAQDTAAETTN CALJAX_49_PE3 ISOFORMIN RHYQCDAGSGSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPTPAQDTATETFI CALJAX_49_PE4 ENSCJAG00000002694 RHYQCDAGSGSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPTPAQDTATETFI CANFAX_43_PE43 NOISO RHHQCDLGSGSDSGSCSSSPSSPSSESSEEDGFFLGERIPLPPHLCRLRPAQDNATGTPK CAVPO132_3_PE22 NOISO ------------------------------------------------------------ DANRE8_54_PE19 NOISO TSLTLYSSRSRHEDSCST---CSSSSDSEEEGFFLGQRIPLPPQLTGQRADEGQTEDEEK DIPORGS_141_PE3 NOISO HRRRCDLGSGSDSGSCSSSPSSPSSESSEDDGLFLGERIPLPPHLCRPKATQDTAAGTFN FUGRU226_PE49 NOISO ----NKPSKYKHEDCCST---CSSSSDSEEEGYFLGQPIPLPPQLRKHQPEEGGE--EER GASACGROUPXII_17_PE4 NOISO PFQTLQPGQCRHEDSCST---CSSSSDSEEEGFFLGQPIPLPPQLRKQQPEEGKDGGGDE HORSEX_41_PE15 NOISO RRHHCDLGSGSDSESCSSSSSSPSSESSEDDGFFLGERIPLPPHLCRPVPAQDTATETPN HSX_PE915 ENSG00000012211 RHYQCDAGSGSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMETFN LOXAF56_2_PE5 NOISO RHHQCDLEPGSDSGSCSSSPSSPSSESSEDDGFFLGERIPLPPHLCRPVSAQESTTETDN MACMUX_48_PE39 NOISO RHYQCDAGSGSDSGSCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDNATETFN MICMUGS_117_PE3 NOISO RHYHCDLGSGSDSGSCSSSPSSSCSESSEDDGFFLGERIPLPAHMCRPMPAQLTATETLN MOUSEX_PE54 NOISO GHHRCDLGSGSDSGSCSSSPSSPSSESSEDDGFFLGERIPLPPHLCRPRTTQDTSTETFN MOUSEX_PE55 NOISO GHHRCDLGSGSDSGSCSSSPSSPSSESSEDDGFFLGERIPLPPHLCRPRTTQDTSTETFN MYOLUGS_1021_PE12 NOISO LHHQCNLG--SDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLTRPLSAQDTATKTPN NEMVE_3395_PE187 NOISO ------------------------------------------------------------ ORYLA7_22_PE45 NOISO PSLTLQLGQFKHEDSCST---CSSSSEEEEEGFFLGQRIPLPPQLQKQQAEESHSRE--- PANTRX_49_PE43 ENSPTRG00000021886 ------------------------------------------------------------ PIGX_44_PE10 NOISO RHHQCDSGSGSDSGSCSSSSTSPSSESSEDDGFFLGERIPLPPHLCRSVPARDTAAETPN PONPYX_50_PE31 NOISO RHYQCDAGSGSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTATETFN PROCAGS_1353_PE2 NOISO KHHQCDLGSGSESGSCSSSPSSPSSESSEDDGFFLGERIPLPPHMCRPVLAQDSTSNTAN PTEVAGS_92_PE3 NOISO CHHQCDSGSGWDSESCSSSPRSSSSESSEDDGFFLGERIPLPPHLCRSVPAQDTAMETSN RATX_PE258 NOISO GHHRCDLGSGSDSGSCSSSPSSPSSESSEDDGFFLGERIPLPPHLCRPKTTQGTATETFN SPETRGS_404_PE2 NOISO GYHRCDLGSGSDSGSCSSSPSSPSSESSEDDGFFLGERIPLPPHLRRPTTSPDSAAETLG TETNG9_PE635 NOISO WPPTLRAGQHKHEDCCST---CSSSSDSEEEGYFLGQPIPLPPQLRKHRPGREVQ----- TRIAD_1217_PE269 NOISO ------------------------------------------------------------ TURTRGS_70_PE3 NOISO RHHRCDLGSGSDSGSCSSSPSSPSSESSEDDGFFLGERIPLPPHLCRPMPAQDTATETPN MATCH CONSENSUS ???????????????CS???????S???E??G?FLG??IPL???????????????????

AILMEGL192563_1_1_PE11 NOISO SPSPQLPRSSRP------GMPRQ---ARDKNCIVA ANOCA505_PE4 NOISO ----------------------------------- BOVIN22_40_PE2 NOISO ----------------------------------- BOVINX_57_PE7 NOISO SPSPQLPGNSRP------GISR---QARDKNCIVA CALJAX_49_PE3 ISOFORMIN SPS-------------------------------- CALJAX_49_PE4 ENSCJAG00000002694 SPS-------------------------------- CANFAX_43_PE43 NOISO SPSPQLPRSWRP------GMPRQ---TRDKNCIVA CAVPO132_3_PE22 NOISO ----------------------------------- DANRE8_54_PE19 NOISO S--------QRGSFRRRRRTQSLGQKDKDKNCILS DIPORGS_141_PE3 NOISO SPAPPLSGDSGP------GMIRQAR----DDCIVA FUGRU226_PE49 NOISO GREVQRDRGLRGSI-RRRRAHSLGAKDRDKNCAIS GASACGROUPXII_17_PE4 NOISO EREGQRDWGLRGS-IRRRRAHSLGAKDKDKNCAIS HORSEX_41_PE15 NOISO SPSPQLPRNSRP------GMPR---QARDKNCTVA HSX_PE915 ENSG00000012211 SPSLSLPRDSRA------GMPRQA---RDKNCIVA LOXAF56_2_PE5 NOISO SPPPLPLGDPRP------RIPRQ---ARDKNCIVA MACMUX_48_PE39 NOISO SPSLSLPRDSRP------GMPRQTRQTRDKNCIVA MICMUGS_117_PE3 NOISO PRSSPLPRDSHP------GMPRQ---SRDKNCIVA MOUSEX_PE54 NOISO SPAQPLVQESHP------VMPRQ---TRDKNCIVA MOUSEX_PE55 NOISO SPAQPLVQESHP------VMPRQ---TRDKNCIVA MYOLUGS_1021_PE12 NOISO SPSPMVPENSGP------GTPRQ---ARDKNCIVA NEMVE_3395_PE187 NOISO ----------------------------------- ORYLA7_22_PE45 NOISO --SQEKDWGLRGSIRRR--ALSQSAKEKEKNCSVS PANTRX_49_PE43 ENSPTRG00000021886 ----------------------------------- PIGX_44_PE10 NOISO SPSPQLPGTSRP------GMSR---QARDKNCIVA PONPYX_50_PE31 NOISO SPSLSLPRDSRP------GMPRQA---RDKNCIVA PROCAGS_1353_PE2 NOISO SPTPLLLRDSHP------GLPRQ---SRAKNCIVA PTEVAGS_92_PE3 NOISO SPFPPP--------------PGNSRQSRDKNCIVA RATX_PE258 NOISO SAAQPLVQESHP------VMPRQ---TRDKNCIVA SPETRGS_404_PE2 NOISO SATPQLHGDSRT------GMPRQ---ARDKNCIVA TETNG9_PE635 NOISO -----PDRGRTGS-LGRSRAHSHGAKDKDKSCSVS TRIAD_1217_PE269 NOISO ----------------------------------- TURTRGS_70_PE3 NOISO SPSPQLPRNSRP------GMPR---QARDKNCIVA MATCH CONSENSUS ???????????????????????????????????


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