Alignment of the gene Family HOG000133031 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL194114_1_PE1 NOISO -MDDLR---------SQNLSMDMTDSSPALANNRLENGMAQLITTEAWNINSTDLVKKA- ANOCA219_1_PE9 NOISO ---------------TQNLPMDVTNSPSTMANNKLENGVAQLITAEAWNINSSDLMKKAL BOVINX_80_PE5 NOISO ------------------------------------------------------------ CALJAX_17_PE10 ISOFORMIN -MDDLQ---------SQNLPMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLV---- CALJAX_17_PE7 ENSCJAG00000003685 -MDDLQ---------SQNLPMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- CALJAX_17_PE8 ISOFORMIN -MDDLQ---------SQNLPMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- CALJAX_17_PE9 ISOFORMIN -MDDLQ---------SQNLPMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- CAVPO59_1_PE2 NOISO -MDDLQ---------SQNLSMDMTDSPPTLANNRLENGMAQLITTEAWNINSTDLVKKA- CHICK1_PE2045 NOISO EELYKE---------TPNLPMDVTSPPAAMANNKLENGVAQLITAEAWNINSADLMKKAL DANRE23_47_PE13 NOISO EELYKASAEVDTAEDAQDLCSTEETDSHTLTLGKLEGEAAAVTTGEPWPAGAPQTPKRSL DASNOGS_6697_PE3 NOISO -MDDLQ---------SRNLAMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- DIPORGS_2735_PE1 NOISO -MDNLQ---------SQNLSMDMTDSPPTLANNRLENGMAQLITTEAWNINSTDLVKKA- ERIEU310555_PE1 NOISO -MDELQ---------SQNLSMDMAESTPALASNRLENGMAQLITTEAWNINSTDLVKKA- FELCAGS_4555_PE2 NOISO -MDDLQ---------SQNLSMDMTDSSPALANNRLENGMAQLITTEAWNINSTDLVKKA- GORGOX_19_PE4 NOISO -MDDLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- HORSEX_14_PE3 NOISO -MDDLQ---------SQNLSMDMTDSSPALANNRLENGMAQLITTEAWNINSTDLVKKA- HSX_PE321 ENSG00000131831 -MDDLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- HSX_PE322 ISOFORMIN -MDDLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- HSX_PE323 ISOFORMIN -MDDLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- HSX_PE324 ISOFORMIN -MDDLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLV---- LAMPAGS_1339_PE1 NOISO -MDDLQ---------SQNLSMDMTDSSPTLTNNRLETPVNTPMTTEAWNINIIVFL--M- LOXAF39_15_PE1 NOISO -MDNLQ---------SQNLPMDMTDSPPSLANNRLENGMAQLITTEAWNINSTDLVKKA- MACEUSCAFFOLD4580_PE1 NOISO PLVDLQ---------SQNLPMDVTSSPPSLANNKLENGVAQLITAEAWNINSTDLMKKAL MACMUX_16_PE8 NOISO -MDNLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- MICMUGS_815_PE1 NOISO -MDDLQ---------SQNLAMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- MONDO7_22_PE4 NOISO EDLYKD---------AQNLPMDVTSSPPSLANNKLENGVAQLITAEAWNINSTDLMKKAL MOUSEX_PE2091 ENSMUSG00000043518 -MDDLQ---------SQNLSMDMTDSPPTLANNRLENRMAQLITTEAWNINSTDLVKKA- MOUSEX_PE2092 ISOFORMIN -MDDLQ---------SQNLSMDMTDSPPTLANNRLENRMAQLITTEAWNINSTDLVKKA- ORYLA4_32_PE9 NOISO ----------------------------------------------PAPPAG-------- OTOGAGS_5097_PE3 NOISO -MDDLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- PIGX_15_PE5 NOISO -MDDLQ---------SQNLSMDMTDSAPALASNRLENGMAQLITTEAWNINSTDLVKKA- PONPYX_18_PE7 NOISO -MDDLQ---------SQNLSMDMTDSPPTLANNRLENGMAQLITTEAWNINSTDLVKKA- PTEVA6776_PE1 NOISO -MDNLQ---------SQNLSMDMTDSSPALANNRLENGMAQLITTEAWNINSTDLVKKA- RABITX_4_PE6 NOISO -MDDLQ---------AQNLPMDMTDSPPALASNRLENGMAQLITTEAWNINSADLVKKA- RATX_PE512 NOISO -MDDLQ---------SQNLSMDMTDSPPTLANNRLENGMAQLITTEAWNINSTDLVKKA- SORARGS_6613_PE3 NOISO -MDDLQ---------AQNLSMDMNDSSPALANNRLENGMAQLITTEAWNINSTDLVKKA- TARSY27045_PE1 NOISO ------------------------------------------------------------ TETNG1_PE622 NOISO ----------------------------------------------PAPSGV-------- TUPGBGS_5291_PE3 NOISO -MDDLQ---------SQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKA- TURTR115894_PE1 NOISO -MDDLQ---------SQNLSMDMTDSSPALANNRLENGMAQLITTEAWNINSTDLVKKA- XENTR92_3_PE13 NOISO EELYKE---------NQDLQIDLNSPPSTLPNNKLENGVAQLITAEAWNINPSGLMKKAL MATCH CONSENSUS ????????????????QNL?MD?T?S?P?LANN?LENG?AQLIT?EAWNINS?DL?KKA?

AILMEGL194114_1_PE1 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN ANOCA219_1_PE9 NOISO SPLVSVPTPSILTPPAESQSGVALKVAATVLQPICLGDSPVVLPIHLQVAGSTSPQIAPN BOVINX_80_PE5 NOISO ------PAPSILNPPAESQSGVALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNQS CALJAX_17_PE10 ISOFORMIN -------------------------------------------------EGSSAPELNPN CALJAX_17_PE7 ENSCJAG00000003685 --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGENPVVMPIHMQVEGSSAPELNPN CALJAX_17_PE8 ISOFORMIN --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGENPVVMPIHMQVEGSSAPELNPN CALJAX_17_PE9 ISOFORMIN --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGENPVVMPIHMQVEGSSAPELNPN CAVPO59_1_PE2 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN CHICK1_PE2045 NOISO SPLVTVPAPSILTPPAESQSGVALKVAATVLQPICLGDSPVVLPIHLQVAGSAAPQMPAS DANRE23_47_PE13 NOISO SPL------------LTLPTSESPAVALKLLQPLCLGDASVVLPILTAP-----PAAPGV DASNOGS_6697_PE3 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSAAPQLNPS DIPORGS_2735_PE1 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGGSAPELNPN ERIEU310555_PE1 NOISO --LVAVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGGSAPELNPS FELCAGS_4555_PE2 NOISO --LVTVPAPSILNPPAESQGGMALKVAATVLQPLCLGESPVVMPIHMQVEGSPAPELNPN GORGOX_19_PE4 NOISO --LATVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN HORSEX_14_PE3 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN HSX_PE321 ENSG00000131831 --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN HSX_PE322 ISOFORMIN --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN HSX_PE323 ISOFORMIN --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN HSX_PE324 ISOFORMIN -------------------------------------------------EGSSAPELNPN LAMPAGS_1339_PE1 NOISO --LVTVPGPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX LOXAF39_15_PE1 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN MACEUSCAFFOLD4580_PE1 NOISO SPLVTVPAPSILTPPAESQSGVALKVAATVLQPICLGDSPVVLPIHLQVAGSTTPQISPN MACMUX_16_PE8 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN MICMUGS_815_PE1 NOISO --LVTVPTPSILNPPAESQGGMALKVAATVLQPLCLGESPVVMPIHMQVEGGSAPELNPN MONDO7_22_PE4 NOISO SPLVTVPAPSILTPPAESQSGVALKVAATVLQPICLGDSPVVLPIHLQVAGSTTPQISPN MOUSEX_PE2091 ENSMUSG00000043518 --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN MOUSEX_PE2092 ISOFORMIN --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN ORYLA4_32_PE9 NOISO SPN------------PEPPGGVALKVATTVIHPVCLGDSPLMLPIHLQMAGASAPQLGQV OTOGAGS_5097_PE3 NOISO --LVTVPAPTILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGGSTPELNPN PIGX_15_PE5 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN PONPYX_18_PE7 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN PTEVA6776_PE1 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQ-EGSSAPELNPN RABITX_4_PE6 NOISO --LVTVPAPSILNPPAEAQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN RATX_PE512 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN SORARGS_6613_PE3 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGGSAPELNPN TARSY27045_PE1 NOISO ------------------------------------------------------------ TETNG1_PE622 NOISO SHA------------AESPGAVALKVATTVLHPVCLGESPLMLPIHLQMSGAAAPQLGQM TUPGBGS_5291_PE3 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPN TURTR115894_PE1 NOISO --LVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSPAPELNPN XENTR92_3_PE13 NOISO SPLVTVPAPTVLSPSSDSQSGVALKVAATVLQPICLGESPVVLPIHWQVAGGTPPQMSTN MATCH CONSENSUS ??LV?VP?P?IL?PPAESQ?G?ALKVAATVLQP?CLG?SPVV?PIH?QV?G??AP?L?P?

AILMEGL194114_1_PE1 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHSNLFQ-GAEDPEAQP ANOCA219_1_PE9 NOISO SNTPYVMTTQGPVPLPLLLEQHVFQHLNSPLVLSQSSPCATNAMHNNIFQ-GSSSPMGQP BOVINX_80_PE5 NOISO GNATYVMTAQGPVQLPVVLEQHVFQHLNSPLVLPPEAPGSSSTIHNNLFQ-GARDPEAQP CALJAX_17_PE10 ISOFORMIN GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNTIHNNLFQ-GAEDPEAQP CALJAX_17_PE7 ENSCJAG00000003685 GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNTIHNNLFQ-GAEDPEAQP CALJAX_17_PE8 ISOFORMIN GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNTIHNNLFQ-GAEDPEAQP CALJAX_17_PE9 ISOFORMIN GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNTIHNNLFQ-GAEDPEAQP CAVPO59_1_PE2 NOISO GNTTYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQ-GAEDSEAQP CHICK1_PE2045 NOISO NATPYVMTTQGPVPLPVLLEQHVFQHLNSPLVLPPGTACPASPLHGSLFP-GASAPVSQP DANRE23_47_PE13 NOISO PAAPYMMSGQGPVSIPLVLEPQVLQHA----LLQQTAACPGLALQSSVLCPNPSLSLGAP DASNOGS_6697_PE3 NOISO GNATYVMAAQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSGAMHSNLFQ-AAESPEAQP DIPORGS_2735_PE1 NOISO ANTTYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHNNLFQ-GAEDPEAQP ERIEU310555_PE1 NOISO SNATYVMTAQGPVQLPVVLEQHVFQHLNSPLVLPQETPCSSGTMHNNLFQ-GPEDPEPQP FELCAGS_4555_PE2 NOISO GHAAYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHNNLFQ-GAEDPEARP GORGOX_19_PE4 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQ-GAEDPEAQP HORSEX_14_PE3 NOISO SNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHNNLFQ-GAEDPEAQP HSX_PE321 ENSG00000131831 GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQ-GAEDPEAQP HSX_PE322 ISOFORMIN GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQ-GAEDPEAQP HSX_PE323 ISOFORMIN GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQ-GAEDPEAQP HSX_PE324 ISOFORMIN GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQ-GAEDPEAQP LAMPAGS_1339_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSIHNNLFQ-GAEDPEAQP LOXAF39_15_PE1 NOISO ANATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQ-GAEDPEAQP MACEUSCAFFOLD4580_PE1 NOISO NNTPYVMTTQGPVPLPVLLEQHVFQHLNSPLVLPQSAACPTNPIHNNLFQ-GTSAPVGQP MACMUX_16_PE8 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEDPCSSNTIHNNLFQ-GAEDSEAQP MICMUGS_815_PE1 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHNNLFQ-GAEDPEAQP MONDO7_22_PE4 NOISO TNTPYVMTTQGPVPLPVLLEQHVFQHLNSPLVLPQSAPCPPNPIHNNLFQ-GASAPVGQP MOUSEX_PE2091 ENSMUSG00000043518 GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQ-GAEDSEAQP MOUSEX_PE2092 ISOFORMIN GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQ-GAEDSEAQP ORYLA4_32_PE9 NOISO GGAPYLITSQSPVSLPLVLDQQVIQHIS-HSVIPQSPGCTQLPRQNSLLCQNP-LTFGLP OTOGAGS_5097_PE3 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHNNLFQ-GAEDPEAQP PIGX_15_PE5 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSGAVHSNLFQ-GAEDPEAQP PONPYX_18_PE7 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQ-GAEDPEAQP PTEVA6776_PE1 NOISO GNATYVMTTQGPMQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQ-AAEDPEAQP RABITX_4_PE6 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHNNLFQ-GTEDSEAQP RATX_PE512 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQ-GAEDSEAQP SORARGS_6613_PE3 NOISO GNATYVMTAQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNTIHNNLFQ-GTDDPEAQP TARSY27045_PE1 NOISO ----YVMTTQGPMQLPVVLEQHVFQHLNSPLVLPQETPCSSNAIHNNLFQ-GAEDPVAQP TETNG1_PE622 NOISO GAAPYLITSPSPVSLPLVLDQQVIQHMS-PSVIPPPPTCPPLPLQNNVLCQNP-LSFGLP TUPGBGS_5291_PE3 NOISO GNATYVMTAQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHNNLFQ-GAEAPEAQP TURTR115894_PE1 NOISO GNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSAIHSNLFQ-GAEDPEAQP XENTR92_3_PE13 NOISO GTTPYVITTQGPVPLPVLLEQHVFQHLNSPLVLPQGSPCPATSLQSHIFP-PAATSVGQP MATCH . :. :: . . * CONSENSUS ?N??YVMT?QGPV?LPVVLEQHVFQHLNSPLVLPQ??PC?????HNNLFQ?GA?????QP

AILMEGL194114_1_PE1 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV ANOCA219_1_PE9 NOISO QLLDQKPSNPAQE-------STPGFAAVLQDLFPS-QGVLGASPYQPSPD--C----SSV BOVINX_80_PE5 NOISO QLLDLRIPSQPQEPPLP-------FEAVLHNLFPA-QGALGPPPCQPPPG--Y----TPV CALJAX_17_PE10 ISOFORMIN QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV CALJAX_17_PE7 ENSCJAG00000003685 QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV CALJAX_17_PE8 ISOFORMIN QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV CALJAX_17_PE9 ISOFORMIN QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV CAVPO59_1_PE2 NOISO QLLDLRIPSQPQEPTLP-------FEAMLQNLFPS-QGSLGPPPCQPPPS--Y----APV CHICK1_PE2045 NOISO QLLDPKPSGPGQEPVLPPVFQTPGFAAVLQDLFPSGQGALGSAPCQPPPD--Y----ATL DANRE23_47_PE13 NOISO PALDQKGPGAGLDTGLLTLLQNPSFAAILQDLFPG---TP-VSACPPPSPPQIDLSSSFL DASNOGS_6697_PE3 NOISO QLLDLRNPSQPQEPPLP-------FETVLQNLFPS-QGALGPPPCQPPPG--Y----PSV DIPORGS_2735_PE1 NOISO QLLDLRIHSQPQEPTLP-------FETVLQNLFPS-QGSLGPPPCQPPPG--Y----APV ERIEU310555_PE1 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALAPPPCQPPPG--Y----ATA FELCAGS_4555_PE2 NOISO QLLDLRIPSRPQEPTLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV GORGOX_19_PE4 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV HORSEX_14_PE3 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV HSX_PE321 ENSG00000131831 QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV HSX_PE322 ISOFORMIN QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV HSX_PE323 ISOFORMIN QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV HSX_PE324 ISOFORMIN QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV LAMPAGS_1339_PE1 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALGPPPCPPPPG--Y----APV LOXAF39_15_PE1 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPA-QGALGPPPCQPPPG--Y----PSV MACEUSCAFFOLD4580_PE1 NOISO QLLDQKPPSQPQEPVLP-------FAAVLQDLFPS-QGTLGSSSCQPPPD--Y----ASV MACMUX_16_PE8 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV MICMUGS_815_PE1 NOISO QLLDLRLPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV MONDO7_22_PE4 NOISO QLLDQKPPSQPQEAVLPPVFQTPGFAAVLQDLFPT-PGTLGSASCQPPPD--Y----ASV MOUSEX_PE2091 ENSMUSG00000043518 QLLDLRIPSQPQEPALP-------FEAVLQNLFPT-QGSLGPPPCQPPPG--Y----APV MOUSEX_PE2092 ISOFORMIN QLLDLRIPSQPQEPALP-------FEAVLQNLFPT-QGSLGPPPCQPPPG--Y----APV ORYLA4_32_PE9 NOISO AAVDPKAAGQAQDANLLSLLQNPAFASIIQDLFPP---QVGPSTCQSPGSSFF----SLP OTOGAGS_5097_PE3 NOISO QLLDLRLPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV PIGX_15_PE5 NOISO QLLDLRIPSQPQEPSLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV PONPYX_18_PE7 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV PTEVA6776_PE1 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV RABITX_4_PE6 NOISO QLLDLRLPSQPQEPTLP-------FEAVLQNLFPS-QGTLGPPPCQPPPG--Y----APV RATX_PE512 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPT-QGSLGPPPCQPPPG--Y----APV SORARGS_6613_PE3 NOISO QLLDLRLPSQPQEPPLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APA TARSY27045_PE1 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV TETNG1_PE622 NOISO PAADPKSAGQTQDTNLLSLLQNPAFAAIMHDLFPS---QAGSSACPSPA----------- TUPGBGS_5291_PE3 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV TURTR115894_PE1 NOISO QLLDLRIPSQPQEPTLP-------FEAVLQNLFPS-QGALGPPPCQPPPG--Y----APV XENTR92_3_PE13 NOISO QILDQKTSSPTQEAVLPPVFTASNFPSVLQDLFPSPNSLGPPSPCHIPPDPYT----STI MATCH * : . : * :::::*** .. . CONSENSUS QLLDLR?PSQPQEP?LP???????FEAVLQNLFPS?QG?LGPPPCQPPP???Y????A?V

AILMEGL194114_1_PE1 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSPESKLSSSFPKPPS ANOCA219_1_PE9 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPVPIPIPIPVPHSAESKVNLDCSKLAS BOVINX_80_PE5 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPLPIPI--PIPVPQSSEAKFSPTCPKPPS CALJAX_17_PE10 ISOFORMIN PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS CALJAX_17_PE7 ENSCJAG00000003685 PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS CALJAX_17_PE8 ISOFORMIN PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS CALJAX_17_PE9 ISOFORMIN PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS CAVPO59_1_PE2 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKPPS CHICK1_PE2045 NOISO PPQAFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPIPVPIPMPHGAEAKVAPDPPK-PP DANRE23_47_PE13 NOISO PPQLPYNTPLAPLVPPATLLVPYPVVIPLPVPLPIPVPIPIPVSIS-KAEAESPKPA--C DASNOGS_6697_PE3 NOISO PPQPFT-APLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPGFPKPPS DIPORGS_2735_PE1 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQNSESKFSSSFPKPPS ERIEU310555_PE1 NOISO APQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSCPKPPT FELCAGS_4555_PE2 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSPESKLSSGFPKPPS GORGOX_19_PE4 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS HORSEX_14_PE3 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKAPS HSX_PE321 ENSG00000131831 PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPMPQSSESKFSSSFPKPPS HSX_PE322 ISOFORMIN PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPMPQSSESKFSSSFPKPPS HSX_PE323 ISOFORMIN PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPMPQSSESKFSSSFPKPPS HSX_PE324 ISOFORMIN PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPMPQSSESKFSSSFPKPPS LAMPAGS_1339_PE1 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS LOXAF39_15_PE1 NOISO PPQSFN-SPLTPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKPPS MACEUSCAFFOLD4580_PE1 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPIPIPIAVPHGSESKLSPDFPK-PP MACMUX_16_PE8 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS MICMUGS_815_PE1 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKPPS MONDO7_22_PE4 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPIPIPIAVPHSSESKLSPDFPK-PP MOUSEX_PE2091 ENSMUSG00000043518 PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PVPVPQSTESKFSPTFPKPPS MOUSEX_PE2092 ISOFORMIN PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PVPVPQSTESKFSPTFPKPPS ORYLA4_32_PE9 NOISO PLTPPYPPALAPLVPPATILVPYPVIIPLPVPLPVPLPVPIPIPQTEDTKGNVPKPV--C OTOGAGS_5097_PE3 NOISO PPQPFN-SPLTPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKPPS PIGX_15_PE5 NOISO PPQPFN-APLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPGCPKAPS PONPYX_18_PE7 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSSSFPKPPS PTEVA6776_PE1 NOISO PPQPFN-PPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPGFSKPPS RABITX_4_PE6 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKPPS RATX_PE512 NOISO PPQPFS-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PVPVPQSSESKFSPSFPKPPS SORARGS_6613_PE3 NOISO PPQTFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSGYG-------KPP TARSY27045_PE1 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKPPS TETNG1_PE622 NOISO --------------------------------------------QPEDTKGNVSKPV--C TUPGBGS_5291_PE3 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFPKPPP TURTR115894_PE1 NOISO PPQPFN-SPLSPLVPPATLLVPYPVIVPLPVPVPIPI--PIPVPQSSESKFSPSFRKPPS XENTR92_3_PE13 NOISO PPQLFSSSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPIPIPMSNSETKGSANEPKS--M MATCH CONSENSUS PPQPF??SPLSPLVPPATLLVPYPVIVPLPVPVPIPI??PIPVPQS?ESK?S???PK?P?

AILMEGL194114_1_PE1 NOISO SFGLHPFKGTQTPLEKEELKPFDILQPREYFQL-SRHTVIKMGSENEALDLSMKSVPWLK ANOCA219_1_PE9 NOISO SFVLHSCKGTQTPLEKEESKPFDFIHHRGLSQL-SRHTVIKMGNENEVLDLSMKPAPLVK BOVINX_80_PE5 NOISO AFGLHPFKGPQSPLQKEE-----------------------MGSENEALDLSMKSVPWLK CALJAX_17_PE10 ISOFORMIN SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK CALJAX_17_PE7 ENSCJAG00000003685 SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK CALJAX_17_PE8 ISOFORMIN SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK CALJAX_17_PE9 ISOFORMIN SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK CAVPO59_1_PE2 NOISO SFSLHSFKGTQTPLEKDELKPLDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK CHICK1_PE2045 NOISO VFTPQPCKGTQTPLEKEETKPFDLVHQRDFSQL-SRHTVIKMGSENEALDLSMKGPPVPR DANRE23_47_PE13 NOISO ----TLSKSTQTPPSDGALYLDS-RDTAGVQQPV---PVPLNSADVEVLDLSTKLPRPSA DASNOGS_6697_PE3 NOISO SCNLHPCKGTPSPLDKEERKPFDILQPREYFQL-SRHTVIKMGSENEALDLSMKSVPWLE DIPORGS_2735_PE1 NOISO SFSLPSFKGTQTSLEKDELKPLDILQPKEYYQL-SRHTVIKMGSENEALDLSMKSVPWLK ERIEU310555_PE1 NOISO SFGLHPFKGTQAPLEK-ELKPFDLLQPREYFQL-SRHTVIKMGSENEALDLSMKSVPWLK FELCAGS_4555_PE2 NOISO SFGLHPFKGTPSPLGKEELKPFDILQPREYFQL-SRHTVIKMGSENEALDLSMKSVPWLK GORGOX_19_PE4 NOISO SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQF-SRHTVIKMGSENEALDLSMKSVPWLK HORSEX_14_PE3 NOISO SFGLHPFKGTQTPLEKEELKPFDIIQPREYFQL-SRHTVIKMGSENEALDLSMKSVPWLK HSX_PE321 ENSG00000131831 SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK HSX_PE322 ISOFORMIN SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK HSX_PE323 ISOFORMIN SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK HSX_PE324 ISOFORMIN SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK LAMPAGS_1339_PE1 NOISO SFGLHPFKGTQPPLQKEELKPFDILQPREYFQL-SRHTVIKMGSENEALDLSMKSVPWLK LOXAF39_15_PE1 NOISO SFSLHPFKGPQPPLEKEELKPFDLLQSREYFQL-SRHTVIKMGSENEALDLSMKSVPWIK MACEUSCAFFOLD4580_PE1 NOISO SFGMYSCKGTQTPLEKEEIKPFNFLQQREFSQL-SRHTVIKMGNENEALDLSMKSMPLLK MACMUX_16_PE8 NOISO SFGLHSFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK MICMUGS_815_PE1 NOISO SFGLHSFKGTQTPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK MONDO7_22_PE4 NOISO SFGMYSCKGTQTPLEKDEIKPFSFLQPREFSQL-SRHTVIKMGNENEALDLSMKSAPLLK MOUSEX_PE2091 ENSMUSG00000043518 SFGLHSFKGTQTTLEKDELKPLDILQSKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK MOUSEX_PE2092 ISOFORMIN SFGLHSFKGTQTTLEKDELKPLDILQSKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK ORYLA4_32_PE9 NOISO ----TVNKSTQTSAKDATSPPPPSRKCPPSFQPQSAT--ASAQEEGQVLDLSVRPC-PIE OTOGAGS_5097_PE3 NOISO SFSLHPFKGTQPPLEKDELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK PIGX_15_PE5 NOISO SFGLQPFRGGPPAVQKEELKPFELLQPREYFQL-SRHTVIKMGSENEALDLSMKSVPWLK PONPYX_18_PE7 NOISO SFGLHPFKGTQTPLEKDELKPFDILQPKEYFQF-SRHTVIKMGSENEALDLSMKSVPWLK PTEVA6776_PE1 NOISO SFGLHPFKGTQTPLEKEELKPFDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK RABITX_4_PE6 NOISO SFNLHPFKGTQPPLEKDELKPLDILQPKEYFQL-SRHTVIKMGSENEALDLSMKSVPWLK RATX_PE512 NOISO SFGLHSFKGTQTTLEKDELKPLDILQPKEYFQL-SRHTVIKMGGENEALDLSMKSVPWLK SORARGS_6613_PE3 NOISO SFGLHPFKGTQTPLEKEELKPFDILQPREYFQL-SRHTVIKMGGENEALDLSMKSVPWPK TARSY27045_PE1 NOISO SFGLHPFKGTQTSLEKDELKSFDILQPKEYFQL-SRHTVIKMGNENEALDLSMKSVPWFK TETNG1_PE622 NOISO ----TVSKSTQTSTSPS---------LLPSFQPQNVSSSSLNPDEGQALDLSVRAC-PLE TUPGBGS_5291_PE3 NOISO SFSLHSFKGTQTPLEKDELKPFDLLQPKDYFQL-SRHTVIKMGSENEALDLSMKSVPWIK TURTR115894_PE1 NOISO SFGLHPFKGTQTPLQKEELKPFDLLPPREYFQL-GRHTVIKMGSENEALDLSMKSVPWLK XENTR92_3_PE13 NOISO AEIQKNCKETQTPLEKEDVKPFDIADRREFSQF-YRHSVIKMSSENEALDLSMKNEPLVL MATCH : .. : :.**** : CONSENSUS SF?L???KGTQ?PL?K?E?KP?D?LQ??E?FQL?SRHTVIKMG?ENEALDLSMKSVPW?K

AILMEGL194114_1_PE1 NOISO AGEVS-PPICQEDAALDLSLAAHRKSEPR--VET-LYDSSGSVDSLG--HSTMEKL-PGG ANOCA219_1_PE9 NOISO ESEES-SQPSPEEGVLDLSIPSCRKTGNTETTSTSHF----GPILEGPAHSTTNKLPT-- BOVINX_80_PE5 NOISO AGEVS-PAMDQEDTALDLSLSAHRKPEPP--PET-LYDSSGSVDSPG--HPVLEKL-PSG CALJAX_17_PE10 ISOFORMIN AGEVS-PPIVQEEAALDLSVAAHRKSEPP--PEI-LYDGGASVDSPG--RAVIEKV-PSG CALJAX_17_PE7 ENSCJAG00000003685 AGEVS-PPIVQEEAALDLSVAAHRKSEPP--PEI-LYDGGASVDSPG--RAVIEKV-PSG CALJAX_17_PE8 ISOFORMIN AGEVS-PPIVQEEAALDLSVAAHRKSEPP--PEI-LYDGGASVDSPG--RAVIEKV-PSG CALJAX_17_PE9 ISOFORMIN AGEVS-PPIVQEEAALDLSVAAHRKSEPP--PEI-LYDGGASVDSPG--RAVIEKV-PSG CAVPO59_1_PE2 NOISO AGEVS-PPIFQEDAALDLSLAAHRKSEPP--PET-LYGNSGSEGSPG--QTVIEKV-PSG CHICK1_PE2045 NOISO ACEAAPPPPSPDDGALDLSLSSCRKPGGPHGETAGSGPSAEGSPQDKPATPFAPSKAP-- DANRE23_47_PE13 NOISO QA--PAPQVLQHDSVLDLSLPSVRKTCIQSRSPFGPLSPER----DRLCHL-GEGISTGA DASNOGS_6697_PE3 NOISO AGEVG-PPAFPEDAVLDLSLAAHRKSEPP--PET-PY--------------------DGG DIPORGS_2735_PE1 NOISO TGEAS-PPIFQEDTALDLSLAAHRKSEPP--PET-LYNKSGP-TNPG--HPVMEKL-PSG ERIEU310555_PE1 NOISO AGETS-PPLCQEDTALDLSLAAHRKLEPPPQAPV-----------ASLGRTGMEKL-PRA FELCAGS_4555_PE2 NOISO AGEAS-PPVCQEDAVLDLSLAAHRKSEPP--VET-LYDSSSSVDSPG--H-------AGG GORGOX_19_PE4 NOISO AGEVS-PPIFQEDAALDLSVAAHRKSEPP--PET-LYDSGASVDSSG--HTVMEKL-PSG HORSEX_14_PE3 NOISO TGEVS-PPICQEDAALDLSLAAHRKSEPL--PET-LYDSSGSVDSPG--HTLMEKL-PGS HSX_PE321 ENSG00000131831 AGEVS-PPIFQEDAALDLSVAAHRKSEPP--PET-LYDSGASVDSSG--HTVMEKL-PSG HSX_PE322 ISOFORMIN AGEVS-PPIFQEDAALDLSVAAHRKSEPP--PET-LYDSGASVDSSG--HTVMEKL-PSG HSX_PE323 ISOFORMIN AGEVS-PPIFQEDAALDLSVAAHRKSEPP--PET-LYDSGASVDSSG--HTVMEKL-PSG HSX_PE324 ISOFORMIN AGEVS-PPIFQEDAALDLSVAAHRKSEPP--PET-LYDSGASVDSSG--HTVMEKL-PSG LAMPAGS_1339_PE1 NOISO AGEVS-PPICQEDAALDLSLATHRKSEPP--PET-LYNSSGSVDSPG--HTVMEKL-PSG LOXAF39_15_PE1 NOISO PGEVS-PPICQEDAVLDLSLATHRKSEPP--PET-LYDNSASADSPG--HPGMEKL-PSG MACEUSCAFFOLD4580_PE1 NOISO ASEVN-LPSYPEDSALDLSLSSSRKAGGSGTLPEAVM--CPSSAMDSPVLPLMEKLSG-- MACMUX_16_PE8 NOISO AGEVS-PPIFQEDAALDLSVAAHRKSEPP--PET-LYDSGASVDSSG--HTVMEKL-PSG MICMUGS_815_PE1 NOISO AGEVS-PPIFQEDAALDLSLAAHRKREPP--PET-LYDSSGSVDSPG--HAVMEKL-PSG MONDO7_22_PE4 NOISO ASALS-PPPYPEDSALDLSLSSSRKAGSSGPLPEAIG--CTGSALDSPALPLMEKLAG-- MOUSEX_PE2091 ENSMUSG00000043518 AGEAS-PPVFQEDAALDLSLAAHRKAEAP--PET-LYNNSGSADIQG--HTILEKL-SSG MOUSEX_PE2092 ISOFORMIN AGEAS-PPVFQEDAALDLSLAAHRKAEAP--PET-LYNNSGSADIQG--HTILEKL-SSG ORYLA4_32_PE9 NOISO PK--QEYPSPQQESVLDLSVPGLRKKSLQADRQVGLQDPRG-----------------AA OTOGAGS_5097_PE3 NOISO AGEVS-PPIFQEDAALDLSLAAHRKPEPP--PET-LYDSSGSVDSPG--HAVMEKL-PSG PIGX_15_PE5 NOISO AGDVS-APACQEDAALDLSLATHRRSEPPPPPET-LCDSSGAVDGPG--HAAMETPPGGG PONPYX_18_PE7 NOISO AGEVS-PPIFQEDAALDLSVAAHRKSEPP--PET-LYDSGASVDSSG--HTVMEKL-PSG PTEVA6776_PE1 NOISO AREVS-PPICQEDAALDLSLAAHRKSEPA--PQT-LYNSSRSMDSPR--HTVVEKL-PRG RABITX_4_PE6 NOISO AGQAS-PAVFQEDTALDLSLAAHRKSEHP--LET-LYDSSGSADSPGHGHTVMEKL-PSA RATX_PE512 NOISO AGEAS-PPVFQEDAALDLSLAAHRKAEVP--PET-LYNTSGSADIQG--HTLLEKR-PSG SORARGS_6613_PE3 NOISO AGEAG-PQTGLEEAALDLSVAAQRKVERP--LEA-PYESGPVA-LDTAAPALMKKP-PSG TARSY27045_PE1 NOISO TGEVS-PQIFQEDAALDLSLAAHRKSDPL--PET-LYDSSGSVENPG--HAVIEKL-SGS TETNG1_PE622 NOISO LK--QEYPAPQQDNVLDLSVPGVRKHVAFPS----GQNTGG-----------------TP TUPGBGS_5291_PE3 NOISO AGEVS-PPIFQEDAALDLSLAAHRKSELP--PET-LFDSSRSADSPG--HAVMEKL-SGG TURTR115894_PE1 NOISO AGEVS-PPMCQEDAALDLSLAAHRKSEPP--PET-LYDSSGSADSPG--HTVMEKL-PSG XENTR92_3_PE13 NOISO NTDVS-TEAIQDDGVLDLSVPVNKRCPNTNTHGSTSV-SC-GSTPDSLSHSTIKSVPIAA MATCH .: .****:. :: CONSENSUS ??E?S?PP??QED?ALDLS????RK????????????????????????????EK?????

AILMEGL194114_1_PE1 NOISO MEVPFAPATVHGAS-A--LMD----S-HVGGSNP-TQLSSQPNQPSGE-----VKA-ENH ANOCA219_1_PE9 NOISO --------AVSPFV-PSKPHEVISSGSSEHLRQPPKWLVDQTNIATCE-----PSA-ANN BOVINX_80_PE5 NOISO MEVPFAPTTTQEAA-S--VME----S-HGGGSDAT----EPPSQPSGE-----VKA-EN- CALJAX_17_PE10 ISOFORMIN MEMSFAPATPHEAP-A--MID----S-HISSSDAATKMLSQPTHPSGE-----VKA-ENN CALJAX_17_PE7 ENSCJAG00000003685 MEMSFAPATPHEAP-A--MID----S-HISSSDAATKMLSQPTHPSGE-----VKA-ENN CALJAX_17_PE8 ISOFORMIN MEMSFAPATPHEAP-A--MID----S-HISSSDAATKMLSQPTHPSGE-----VKA-ENN CALJAX_17_PE9 ISOFORMIN MEMSFAPATPHEAP-A--MID----S-HISSSDAATKMLSQPTHPSGE-----VKA-ENN CAVPO59_1_PE2 NOISO TEVPFTPATSREAS-T--TMD----S-HMGGSNP-AEMVSQASQPSSE-----VKA-ENN CHICK1_PE2045 NOISO --------EAAGKA-EGRVVG---PGSGELLRPPQKWLVEPAGRAACE-----PKAGGNN DANRE23_47_PE13 NOISO LAL--GVLRPVDCT-PKLDSKLLSGLASLEFSRQHKWVVDSSVAGSGSVH-DSALTAGGN DASNOGS_6697_PE3 NOISO RDMPFAPATPHEAS-A--RME----S-HGNSG-EAPEMPSQPRQPGGE-----VKA-ENH DIPORGS_2735_PE1 NOISO MEMPFAPAMLPEAS-A--MMD----S-HSSNSNA-VEMVSQPSYPSSD-----VKA-ENN ERIEU310555_PE1 NOISO VETPFATATTLEAM-A--MLD----GRTVNSSPAAASAPEQPNQPCSE-----LKA-ESS FELCAGS_4555_PE2 NOISO MEVPFAPATAHGAS-A--VMD----S-HVGGSNP-AQLPGQPGQPSGE-----VKA-ENP GORGOX_19_PE4 NOISO MEISFAPDTSHEAP-A--MMD----S-HISSSDAATEMLSQPNHPSGE-----VKA-ENN HORSEX_14_PE3 NOISO MEMPFGPATPREAS-A--MMD----S-HMGSSDTA-EPLSQPSQPSSE-----VKA-ENN HSX_PE321 ENSG00000131831 MEISFAPATSHEAP-A--MMD----S-HISSSDAATEMLSQPNHPSGE-----VKA-ENN HSX_PE322 ISOFORMIN MEISFAPATSHEAP-A--MMD----S-HISSSDAATEMLSQPNHPSGE-----VKA-ENN HSX_PE323 ISOFORMIN MEISFAPATSHEAP-A--MMD----S-HISSSDAATEMLSQPNHPSGE-----VKA-ENN HSX_PE324 ISOFORMIN MEISFAPATSHEAP-A--MMD----S-HISSSDAATEMLSQPNHPSGE-----VKA-ENN LAMPAGS_1339_PE1 NOISO VEMPFAPAAPHEAS-A--MMD----T-HVGGS-NTTEPPSQPSQPSGE-----VKA-ENN LOXAF39_15_PE1 NOISO AEMPFPLATPHEAS-T--VME----N-RICSSNA-PEMLSQPSHPSGE-----VKA-ENN MACEUSCAFFOLD4580_PE1 NOISO --------TVIPFT-QPKPLETTIKDSRNSSSEATAEVAGQTSRPGCE-----PKT-GNN MACMUX_16_PE8 NOISO MEISFAPTTSHEAP-A--MID----G-HISSSDAATEMLSQPNHASSE-----VKT-ENN MICMUGS_815_PE1 NOISO MEMPFVPATPHEAS-A--MVD----S-HSSSSDTAE----LPSHPGGE-----VKA-ENN MONDO7_22_PE4 NOISO --------NS----------------------------KSGCGRPGCE-----PKT-GNN MOUSEX_PE2091 ENSMUSG00000043518 MEMPFAPAKCSEAS-A--MME----S-HSSNSNG-TEMVSQPSHPGSE-----LKA-ENN MOUSEX_PE2092 ISOFORMIN MEMPFAPAKCSEAS-A--MME----S-HSSNSNG-TEMVSQPSHPGSE-----LKA-ENN ORYLA4_32_PE9 NOISO L------SLGVECS-QSLDSKLLGSLASLEFSRQHKWVVDTSATGSSSLAQEASLSGAGN OTOGAGS_5097_PE3 NOISO MEIPFAPATPHEAS-A--MMD----S-HISSSNAAE----MPTHPSSE-----VKA-ENN PIGX_15_PE5 NOISO VEVPFAPATPHEAA-AAAAME----R-HLGGSDAA----EPPRQPSGE-----VKA-ENN PONPYX_18_PE7 NOISO MEISFAPATSHEAP-A--MMD----S-HISSSDAATEMLSQPNHPSSE-----VKA-ENN PTEVA6776_PE1 NOISO MEMPFVPATTREAL-A--MMN----S-HMGSSNTA-QPHSQPSQPSSM-----VKA-ENN RABITX_4_PE6 NOISO TETPFAPATPREAS-A--TMD----S-HSSSGASASEMPSQPSQPSGE-----VKA-ENN RATX_PE512 NOISO MEMPFAPAKSREAS-A--MMD----S-HSSSSNG-TEMVSQPIHPGSE-----LKP-ENN SORARGS_6613_PE3 NOISO ER-TFAAD-----S-QAAPVG----LRTQVGGSDTPEQLNQPPQPGGD-----VKP-EGS TARSY27045_PE1 NOISO MEIPFTPVTPHEAS-A--TVD----S-HMSSSDATTEMLSQPSQSSGE-----VKA-ENN TETNG1_PE622 NOISO L------SLGVECT-QSLDSKVLGSLASLEFSRKHKWVVDGNAGGSASRSQETSLGGSGN TUPGBGS_5291_PE3 NOISO MEMPFAPATPQEAS-S--MMD----S-HTSSSNAEM----LQPS---------------- TURTR115894_PE1 NOISO TEVPFAPATPHEAS-A--AMD----S-HMGSSVAA-EP---PSQPSSE-----VKA-ENN XENTR92_3_PE13 NOISO S---FSPPLLHPELAQKQDSKVICTNT-AELLRQPKWIPEQSIRAAYE-----PKP-SNN MATCH CONSENSUS ????F??????????????????????????S???????????????E??????K???NN

AILMEGL194114_1_PE1 NOISO IEIVSESQAAKVIVSVEDAMPAIFCGKVKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ ANOCA219_1_PE9 NOISO IEIVSTSQTAKVIVSVKDAVPTIFCGKIKGLSGVSTKNFSFKRDMPQDSVL-QCYDVKNQ BOVINX_80_PE5 NOISO --LVSESQAAKVIVSVEDTVPTIFCGKIKGLSGVSTKNFSFRRE---DSVF-QGSDANSP CALJAX_17_PE10 ISOFORMIN IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ CALJAX_17_PE7 ENSCJAG00000003685 IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ CALJAX_17_PE8 ISOFORMIN IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ CALJAX_17_PE9 ISOFORMIN IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ CAVPO59_1_PE2 NOISO TEIGSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINNQ CHICK1_PE2045 NOISO IEIVSTSQTAKVIVSVKDAVPAIFCGKIKGLSGVSTKNFSFKRDMPQDSVL-QCYDVKSQ DANRE23_47_PE13 NOISO IEIVSTSQTAKVIVSVKDAMPAIFCSKIKGLSGVSTKNFSIKCDGGQGAFA----TLPRG DASNOGS_6697_PE3 NOISO RELVSDSQAAKVIVSVEDAVPAIFCGKAKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ DIPORGS_2735_PE1 NOISO TEVVSESQAAKVIVSVEDTMPTIFCGKIRGLSGVSTKNFSFKRE---DSVL-QGYDINTQ ERIEU310555_PE1 NOISO TEAVSESQATKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYGINSQ FELCAGS_4555_PE2 NOISO MEIVSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ GORGOX_19_PE4 NOISO IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ HORSEX_14_PE3 NOISO IEVGSESQVAKVIVSVEDAVPAVFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ HSX_PE321 ENSG00000131831 IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ HSX_PE322 ISOFORMIN IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ HSX_PE323 ISOFORMIN IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ HSX_PE324 ISOFORMIN IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ LAMPAGS_1339_PE1 NOISO IEIVSESQAAKVIVSVEDTVPTIFCGKIKGLSGVSTKNFSFKRE---DSML-QGYDIHSQ LOXAF39_15_PE1 NOISO MEIVGECQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSIKRE---DSVL-QGYNINSQ MACEUSCAFFOLD4580_PE1 NOISO IEIVSTSQTAKVIVSVKDAVPTIFCGKIKGLSGVSTKNFSFKRDLPQDSVL-QCYDVKGQ MACMUX_16_PE8 NOISO IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ MICMUGS_815_PE1 NOISO VEIASESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ MONDO7_22_PE4 NOISO IEIVSTSQTAKVIVSVKDAVPTIFCGKIKGLSGVSTKNFSFKRDLPQDSVL-QCYDVKGQ MOUSEX_PE2091 ENSMUSG00000043518 IEILSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ MOUSEX_PE2092 ISOFORMIN IEILSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ ORYLA4_32_PE9 NOISO LEIVSASQTAKVIVSVKDAIPAILCGKIKGLSGVSTKNFSIKRDGSQGPSLQQLYGVPSG OTOGAGS_5097_PE3 NOISO IESVSESQAAKVIVSVEDAVPNIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ PIGX_15_PE5 NOISO IELGSESQAAKVIVSVEDTVPTIFCGKIKGLSGVSTKNFSFKRE---DAML-QGYDISSQ PONPYX_18_PE7 NOISO IEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ PTEVA6776_PE1 NOISO IEMVSDSQASKVIVSVEDAMPTVFCGKIKGLSGVSTKNFSFKRE---DSVF-QGYDINSQ RABITX_4_PE6 NOISO IELVNESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ RATX_PE512 NOISO IEIVSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ SORARGS_6613_PE3 NOISO LEVAGESQAPKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKRE---DSVL-QGYDINSQ TARSY27045_PE1 NOISO IEIVSESQAAKVIVSVEDSVPTIFCGKIKGLSGVSTKNFSFKRE---DSML-QGYDINSQ TETNG1_PE622 NOISO LEIVSTSQTAKVIVSVKDGIPAILCGKIKGISGVSTKNFSIKRDGGQGSSLQQLYGAPSG TUPGBGS_5291_PE3 NOISO ------------------------------------------------------------ TURTR115894_PE1 NOISO IEIVSESQAAKVIVSVEDTVPTIFCGKIKGLSGVSTKNFSFKRE---DSML-QGYDINSP XENTR92_3_PE13 NOISO IELVSSSQTAKVIVSVKDAVPAIFCGKIKGLSGVSTKNFSFKRDLPQDSAA-QCYEMKSQ MATCH CONSENSUS ?E?V??SQ?AKVIVSV?DAVP?IFCGKIKGLSGVSTKNFSFKR????DS?L?Q?YD??SQ

AILMEGL194114_1_PE1 NOISO GEEPMGSTEPLRKPV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK ANOCA219_1_PE9 NOISO PE-ARDTAEALRKPI-KNRNVKLKKMNSQEIHILPIKKQRLAAFFPRK BOVINX_80_PE5 NOISO GEEALGNMEALRKPT-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK CALJAX_17_PE10 ISOFORMIN GEESMGNAEPLRKSI-KNRSIKLKKMNSQEIHMLPIKKQRLATFFPRK CALJAX_17_PE7 ENSCJAG00000003685 GEESMGNAEPLRKSI-KNRSIKLKKMNSQEIHMLPIKKQRLATFFPRK CALJAX_17_PE8 ISOFORMIN GEESMGNAEPLRKSI-KNRSIKLKKMNSQEIHMLPIKKQRLATFFPRK CALJAX_17_PE9 ISOFORMIN GEESMGNAEPLRKSI-KNRSIKLKKMNSQEIHMLPIKKQRLATFFPRK CAVPO59_1_PE2 NOISO GEDSMGNVEPLRKPI-KSRSIKLKKVNSQEIHMLPIKKQRLATFFPRK CHICK1_PE2045 NOISO PE-PRDNAEALRKPV-KNRSVKLKKMNSPEIHILPIKKQRLAAFFPRK DANRE23_47_PE13 NOISO PGDPRGEPSDTLKKISKNRGIKLKKVSSQEIHILPIKKQR-------- DASNOGS_6697_PE3 NOISO GEESVENAEPLRKAV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK DIPORGS_2735_PE1 NOISO GEESLGNMESHRKPI-KNRGIKLKKMNSQEIHMLPIKKQRLATFFPRK ERIEU310555_PE1 NOISO GEESLGSVEALRKPV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK FELCAGS_4555_PE2 NOISO GEEPMGSTEPLRKPV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK GORGOX_19_PE4 NOISO GEESMGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK HORSEX_14_PE3 NOISO GEEAMGNMESLRKPV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK HSX_PE321 ENSG00000131831 GEESMGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK HSX_PE322 ISOFORMIN GEESMGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK HSX_PE323 ISOFORMIN GEESMGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK HSX_PE324 ISOFORMIN GEESMGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK LAMPAGS_1339_PE1 NOISO GEESMGNTESLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK LOXAF39_15_PE1 NOISO GEEAVENTEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK MACEUSCAFFOLD4580_PE1 NOISO AE-SRENAESLRKPI-KNRSVKLKKMNSQEIHLPIK------------ MACMUX_16_PE8 NOISO GEESMGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK MICMUGS_815_PE1 NOISO GEESMGNAEPLRKPV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK MONDO7_22_PE4 NOISO AE-SRENAESLRKPI-KNRSVKLKKMNSQEIHILPIKKQRLAAFFQES MOUSEX_PE2091 ENSMUSG00000043518 GEESLGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK MOUSEX_PE2092 ISOFORMIN GEESLGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK ORYLA4_32_PE9 NOISO SHREQQDPNNPHKKVSKSRAIKLKKVSSQEIHFLPIKKQRLAALLPRK OTOGAGS_5097_PE3 NOISO GEESMGNAEPLRKPI-KNRSIKLKKVNSQEIHMLPLKKQRLATFFPRK PIGX_15_PE5 NOISO AEESAGSAEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK PONPYX_18_PE7 NOISO GEESMGNAEPLRKPI-KSRSIKLKKVNSQEIHMLPIKKQRLATFFPRK PTEVA6776_PE1 NOISO GEESMGNTESLRKPVVKSRSIKFKKVNSQEIHMLPIKKQRLATFFPRK RABITX_4_PE6 NOISO GEEAMGNSEPIRKPV-KNRSIKLKKMNSQEIHMLPIKKQRLATFFPRK RATX_PE512 NOISO EDESLGNTEPLRKPI-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK SORARGS_6613_PE3 NOISO GEEALGGAEPFRKPI-KNRCIKLKKVNSQEIHMLPIKKQRLATFFPRK TARSY27045_PE1 NOISO EEESMGNAEPLRKPV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK TETNG1_PE622 NOISO SHPDQSNPSHVLKKVPKSRAIKLKNISSQEIHFLPVKKQRLAALLPRK TUPGBGS_5291_PE3 NOISO ------------------------------------------------ TURTR115894_PE1 NOISO GEESMGNAEPLRKPV-KNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK XENTR92_3_PE13 NOISO AE-HRENAEALRKPI-KNRSVKLKKVNSQEIHILPIKKQRLAAFFPRK MATCH CONSENSUS ?E??????E?LRK???KNRSIKLKK?NSQEIH?LPIKKQRLA?FFPRK


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