Alignment of the gene Family HOG000139424 of HOGENOM

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Isoforms are ON
ANOCA447_1_PE4 NOISO ------------------------------------------------------------ CANFA10_21_PE31 NOISO -------------------------------------------------LWSVMENNQET CAVPO184_1_PE35 NOISO --------------------------------------------------WSVMESNQES CHICK1_PE251 NOISO -----------------------------------------------------MENSKSG DANRE4_28_PE4 NOISO DSEDSLSQKTEVASHRHNGSKDNKRIEAKGTCLKIEGKDGYVFKSYRITPQEILESEFHT DIPORGS_3277_PE1 NOISO -----------------------------------------------------MEKLREA ECHTEGS_6359_PE1 NOISO -----------------------------------------------------MDAGQQA FELCAGS_742_PE2 NOISO -----------------------------------------------------MENNQEP GASACGROUPIV_21_PE16 NOISO ------------------------------------------------------------ GORGO22_36_PE1 NOISO -----------------------------------------------------MENNLKT HS22_PE2380 NOISO -----------------------------------------------------MENNLKT LOXAF176_PE11 NOISO -----------------------------------------------------MDNSQDT MACEUSCAFFOLD45461_PE1 NOISO -----------------------------------------------------MDKNQET MACMU10_97_PE1 NOISO -----------------------------------------------------MENKLKT MICMUGS_737_PE1 NOISO -----------------------------------------------------MEDNLET MONDO8_8_PE4 NOISO ----------------------------------------------------IMDKNQET MOUSE15_PE1119 ENSMUSG00000034333 -----------------------------------------------------MEDKQET MOUSE15_PE1120 ISOFORMIN -----------------------------------------------------MEDKQET MYOLU110252_PE1 NOISO -----------------------------------------------------MENNQET MYOLU143333_PE2 NOISO -----------------------------------------------------MENNQET ORYLA23_7_PE29 NOISO ------------------------------------------------------------ PANTR22_51_PE7 NOISO -----------------------------------------------------MENNLKT PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO -----------------------------------------------------MENNLKT RAT7_PE1614 NOISO -----------------------------------------------------MEDKQEV RAT7_PE185 NOISO ------------------------------------------------------------ TETNG19_PE312 NOISO ------------------------------------------------------------ TURTR85811_PE1 NOISO -----------------------------------------------------MENHQET XENTR20_2_PE12 ENSXETG00000014526 -------------------------------------------------MWTLFSCNHKL XENTR20_2_PE13 ISOFORMIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ANOCA447_1_PE4 NOISO ------------------------------------------------------------ CANFA10_21_PE31 NOISO -RPRRDGEFVSD--KINFKIEEEDD----------------------------------V CAVPO184_1_PE35 NOISO -CPKGDEDFDSD--KINFKIEEEDD----------------------------------D CHICK1_PE251 NOISO -SPITDGNFILG--KINN-LKVEQE----------------------------------E DANRE4_28_PE4 NOISO -CPSETLAKDSSLVSLSFESTEEDGSSEVERLSTEDSTAESCEKHDSQTSPNISNKSQNT DIPORGS_3277_PE1 NOISO -CPPGDGGFISN--KGDFKPEEDDD----------------------------------N ECHTEGS_6359_PE1 NOISO -CPHVRSEFASQ--KTAFKAEEEDD----------------------------------A FELCAGS_742_PE2 NOISO -RPKGDGQFVSA--KRNFKIEGE-D----------------------------------V GASACGROUPIV_21_PE16 NOISO ------------------------------------------------------------ GORGO22_36_PE1 NOISO -CPKEDGDFVSD--KIKFKIEEEDD----------------------------------D HS22_PE2380 NOISO -CPKEDGDFVSD--KIKFKIEEEDD----------------------------------D LOXAF176_PE11 NOISO -CPKVDSEFVSD--KITFKIAVEDG----------------------------------D MACEUSCAFFOLD45461_PE1 NOISO -CPKVDNSFVLD--KIN--FKVEPE----------------------------------D MACMU10_97_PE1 NOISO -CPKEDGDFVSD--KIKFKIEEEDD----------------------------------D MICMUGS_737_PE1 NOISO -CPKGDSDFVSD--KINFKIEEEDDD---------------------------------D MONDO8_8_PE4 NOISO -CSKMDNSFVLD--KIN--FKVEPE----------------------------------D MOUSE15_PE1119 ENSMUSG00000034333 -CPKGDSDFVSD--KVNFKTEE-DD----------------------------------D MOUSE15_PE1120 ISOFORMIN -CPKGDSDFVSD--KVNFKTEE-DD----------------------------------D MYOLU110252_PE1 NOISO HPPKGDGDFVSD--KINVKIEEE-D----------------------------------D MYOLU143333_PE2 NOISO YSRKGDGDFVSD--KINFKIEEE-D----------------------------------D ORYLA23_7_PE29 NOISO ------------------------------------------------------------ PANTR22_51_PE7 NOISO -CPKEDGDFVSD--KIKFKIEEEDD----------------------------------D PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO -CPKEDGDFVSD--KIKFKIEEEDD----------------------------------D RAT7_PE1614 NOISO -CPEGDRDFVSD--KVNFKIEEEDE----------------------------------D RAT7_PE185 NOISO ------------------------------------------------------------ TETNG19_PE312 NOISO ------------------------------------------------------------ TURTR85811_PE1 NOISO -RPEAGRDFVSD--QIHFKIEEEDD----------------------------------D XENTR20_2_PE12 ENSXETG00000014526 -SPKMESNLAEE--KSND-LKVED-----------------------------------D XENTR20_2_PE13 ISOFORMIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ANOCA447_1_PE4 NOISO -----ALE-TIDIKTEPEDLRQTDSSDEQDE-QERNFIHSNSSKYISAENEDDYGSLFSQ CANFA10_21_PE31 NOISO QIPNPSLE-GVEFKAEPDGNRA--------------------EECPAADQEEEYGSLFSQ CAVPO184_1_PE35 NOISO QAPGHCLD-RMDFQSEQEDMRPTDSGDEQEAGGVAGCACRPPGQCLPTEGEDEYGALFSQ CHICK1_PE251 NOISO DGINCTLE-RMDIKTEQDEFKHADSSDEQED-KEKNFISNNPSKYLSTENEDDYGSLFSQ DANRE4_28_PE4 NOISO EINNSETETSVCIKAEPKVTGE------NAQDDEKLAFDGTFGPFATRGYDDDYGSLFSG DIPORGS_3277_PE1 NOISO QNPGGGMG-RTDFKSEPEGPRQADRGELA---DEVDCACRPP-----PESEDDCGALFSQ ECHTEGS_6359_PE1 NOISO GVPVPS-PRRMDLRGELGAP-PCSHGHRALEGRGVDCASALPGKYLPGDVEDDYGSLFSQ FELCAGS_742_PE2 NOISO RLPNHGLE-GVEFSEQ--DRKRADGGGERAEAGEXXXXXXXXXXXXXXXXXXXXXXXXXX GASACGROUPIV_21_PE16 NOISO ---------------------------------------------------DEYSNLFSG GORGO22_36_PE1 NOISO GIPPDSLE-RMDFKSEQEDMKQTDSGGERAGLGGTGCSCKPPGKYLSAESEDDYGALFSQ HS22_PE2380 NOISO GIPPDSLE-RMDFKSEQEDMKQTDSGGERAGLGGTGCSCKPPGKYLSAESEDDYGALFSQ LOXAF176_PE11 NOISO RIPSHSLE-RMDLRSERGHPQHTDSGEEHLEGREADCACPPPGKYLHSDNENDYGSLFSQ MACEUSCAFFOLD45461_PE1 NOISO NITNHSSE-RMNFKSEQEDVRQTDSSDEQAEFKGKNCSSRHPGKYSSPDNEEDYGSLFSQ MACMU10_97_PE1 NOISO GIPPDSLE-RMDFKSEQQDMKQTDSGGERAGLGGTGCSCKPPGKYLSAESEDDYGALFSQ MICMUGS_737_PE1 NOISO PTPAHSLE-RVDLKREREDMNQTDSSDEQAEAREASCNGKPPGKHLPPESEDDYGSLFSQ MONDO8_8_PE4 NOISO NTTNHSVE-RMDFKSEQEDVRQTDSSDEQAEFKGKTCSGRHPGKCSSADHEEDYGTLFSQ MOUSE15_PE1119 ENSMUSG00000034333 QTPCHSLE-QVDFKSESEDMRQTDSGDEQADIRAASCACQPSGKFLAAESEDDYGSLFSQ MOUSE15_PE1120 ISOFORMIN QTPCHSLE-QVDFKSESEDMRQTDSGDEQADIRAASCACQPSGKFLAAESEDDYGSLFSQ MYOLU110252_PE1 NOISO GIPNHSLE-RVDFKIEQEDRKAAGSGDEQAEIREASYSCKPPGKCFPADHEDDYGALFSQ MYOLU143333_PE2 NOISO GIPNHSLE-RVDFKIEQEDRKAAGSGDEQAEIREASYSCKPPGKCFPADHEDNYGALFSQ ORYLA23_7_PE29 NOISO ------------------------------------------------------------ PANTR22_51_PE7 NOISO GIPPDSLE-RMDFKSEQEDMKQTDSGGERAGLGGTGCSCKPPGKYLSAESEDDYGALFSQ PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO GIPPDSLE-RMDFKSEQEDMKQTDSGGERAGLGGTGCSCKPPGKYLSAESGDDYGTLFSQ RAT7_PE1614 NOISO QIPCHSLQRRMDFKSESEDMRQTDSGDEQAEIRAASCACQPSGKFLPAESEDDYGSLFSQ RAT7_PE185 NOISO ------------------------------------------------------------ TETNG19_PE312 NOISO ---------------------------------------------------DDYSNLLSG TURTR85811_PE1 NOISO HIADHSLE-RMDFRNEQENRKRAGSGDERAEGREASCGCQPPGRRVSPDPEDDYGALLSQ XENTR20_2_PE12 ENSXETG00000014526 EDRNSDLD-GMQIKMESDDLKQTESSDEQEDKD--QFCADTSNTFVSAENEDDYGVLFSQ XENTR20_2_PE13 ISOFORMIN ----------------------------QEDKD--QFCADTSNTFVSAENEDDYGVLFSQ MATCH CONSENSUS ?????????????????????????????????????????????????????YG?LFS?

ANOCA447_1_PE4 NOISO YSSTLYDVAMEAVTQSLLSSR--NISSRKKSPAWNHFFISPRDSTKAICMYCMKEFSRGK CANFA10_21_PE31 NOISO YSSTLYDVAMEAVTQSLLSGR--AVSSRKKSPAWKHFFISPRDSTKAICTYCMKEFSRGK CAVPO184_1_PE35 NOISO YSSTLYTVAMEAVTQSLLSSR--HLSSRKKSPAWQHFFISPRDSTKAICRYCMKEFSRGK CHICK1_PE251 NOISO YSSTLYDVAMEAVTQSLLSSR--NISSRKKSPAWNHFFISPRDSTKAICMYCMKEFSRGK DANRE4_28_PE4 NOISO YSSTLYDVAMDAVTQSLLSSIRSPLNPRKKSPAWNHFFISPRDSTKAICMYCMKEFSRGK DIPORGS_3277_PE1 NOISO YSSTLYSVAMEAVAQSLLSSR--HASSRKKSPAWKHFFISPRDSTKAICTYCMKEFSRGK ECHTEGS_6359_PE1 NOISO YSSTLYDVAMEAVTQSLLSSR--QLSSRKKSPAWKHFFISPRDSTKAVCVYCVKEFSRGK FELCAGS_742_PE2 NOISO XXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX GASACGROUPIV_21_PE16 NOISO YTSTLYDVAMDAVTQSLLSSMRSNANPRKKSPAWNHFCISPRDGTKAICLYCMKEFSRGK GORGO22_36_PE1 NOISO YSSTLYDVAMEAVTQSLLSSR--NMSSRKKSPAWKHFFISPRDSTKAICMYCVKEFSRGK HS22_PE2380 NOISO YSSTLYDVAMEAVTQSLLSSR--NMSSRKKSPAWKHFFISPRDSTKAICMYCVKEFSRGK LOXAF176_PE11 NOISO YSSTLYDVAMEAVTQSLLSSR--TINSRKKSPAWKHFFISPRDSTKAICMYCMKEFSRGK MACEUSCAFFOLD45461_PE1 NOISO YSSTLYDVAMEAVAQSLLSSR--NISSRKKSPAWNHFFISPRDSTKAICMYCMKEFSRGK MACMU10_97_PE1 NOISO YSSTLYDVAMEAVTQSLLSSR--NMSSRKKSPAWKHFFISPRDSTKAICMYCVKEFSRGK MICMUGS_737_PE1 NOISO YSSTLYDVAMEAVTQSLLCSR--NISSRKSP---AHFFISPRDSTKAICXN--------- MONDO8_8_PE4 NOISO YGSTLYDVAMEAVAQSLLSSR--NISSRKKSPAWNHFFISPRDSTKAICMYCMKEFSRGK MOUSE15_PE1119 ENSMUSG00000034333 YSSTLYSVAMEAVTQSLLSSR--HISSRKKSPAWKHFFISPRDSTKAICTYCMKEFSRGK MOUSE15_PE1120 ISOFORMIN YSSTLYSVAMEAVTQSLLSSR--HISSRKKSPAWKHFFISPRDSTKAICTYCMKEFSRGK MYOLU110252_PE1 NOISO YSSTLYDVAMEAVTQSLLSSR--SMNSRKKSPAWKHFFISPRDSTKAVCVYCMKEFSRGK MYOLU143333_PE2 NOISO YSSTLYDVAMEAVTQSLLSSR--SMNSRKKSPAWKHFFISPQDTTKAVCVYCMKEFSRGK ORYLA23_7_PE29 NOISO ------------------------------------------------------------ PANTR22_51_PE7 NOISO YSSTLYDVAMEAVTQSLLSSR--NMSSRKKSPAWKHFFISPRDSTKAICMYCVKEFSRGK PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO YSSTLYDVAMEAVTQSLLSSR--NMSSRKKSPAWKHFFISPRDSTKAICMYCVKEFSRGK RAT7_PE1614 NOISO YSSTLYNVAMEAVTQSLLSSR--HISSRKKSPAWKHFFISPRDSTKAICTYCMKEFSRGK RAT7_PE185 NOISO ------------------------------------------------------------ TETNG19_PE312 NOISO YTSTLYDVAMDAVTQSLLSSMRSNANPRKKSPAWNHFCISPRDSTKAICLYCMKEFSRGK TURTR85811_PE1 NOISO YNSTLYSVAMEAVTQSLLSGR--GISSRKKSPAWKHFFISPRDSTKAICTYCMKEFSRGK XENTR20_2_PE12 ENSXETG00000014526 YTTTLYDAAMEAVTQSILTNK--NISNRKKSPAWNHFFISPRDSTKAICMYCMKEFSRGK XENTR20_2_PE13 ISOFORMIN YTTTLYDAAMEAVTQSILTNK--NISNRKKSPAWNHFFISPRDSTKAICMYCMKEFSRGK MATCH CONSENSUS Y?STLY?VAM?AV?QSLL?????????RKKSPAW?HFFISPRDSTKA?C?YC?KEFSRGK

ANOCA447_1_PE4 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSIPTIPSFSS-PPLLISPQPV--DVGDLTGVLA CANFA10_21_PE31 NOISO NEKDLSTSCLMRHVRRAHPTVLVQENGSVPGLPSLSP-PPLRLPPQPT--DPGDLGAVLS CAVPO184_1_PE35 NOISO NEKDLSTSCLMRHVRRAHPTKLAPDGGSLAVG-SFPA-PSLLLPPQPA--DTGDLGATLS CHICK1_PE251 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGTMPNISSFSS-PTLLLPPQSA--DMGDLSSMLS DANRE4_28_PE4 NOISO NEKDLSTSCLMRHVRRAHPSVLLPDSDSLNNLS----NNSSLIPP-NISPNNGDLPASM- DIPORGS_3277_PE1 NOISO NEKDLSTSCLMRHVRRAHPTKLLQEDGSLSSGAACPS-PSALLPAPPT--DGGDLGTTLS ECHTEGS_6359_PE1 NOISO NEKDLSTSCLMRHVRRAHPTALLPGPXXXXXXXXXXX-XXX------------------- FELCAGS_742_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX--XXXXXXXXXX GASACGROUPIV_21_PE16 NOISO NEKDLSTSCLMRHVRRAHPTVLMADGADVSSNHLAGSLASSLIPPSPNSPKNGDLMNSV- GORGO22_36_PE1 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSVSAVSSFPS-PSLLLPPQPA--DAGDLSTILS HS22_PE2380 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSVSAVSSFPS-PSLLLPPQPA--DAGDLSTILS LOXAF176_PE11 NOISO NEKDLSTSCLMRHMKRAHPTVLIQENGSASGMASFSS-PSLLLPPQSA--DAGDLSTILS MACEUSCAFFOLD45461_PE1 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSMPSIASFPS-PSLLLPPQPA--DVGDLSTVLS MACMU10_97_PE1 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSVSAVSSFPS-PSLLLPPQPA--DTGDLSTILS MICMUGS_737_PE1 NOISO --EKDSTSCLMRHVRRAHP-VLIQENGSLSAVSYIPS-PRSLLPPQPA--EAGDLSTILS MONDO8_8_PE4 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSMPSISSFPS-PSLLLPPQPA--DVSDLSTVLS MOUSE15_PE1119 ENSMUSG00000034333 NEKDLSTSCLMRHVRRAHPTKLIQENGSLSAGSSFSP-PSLLLPPQPA--DVGDLSTVLS MOUSE15_PE1120 ISOFORMIN NEKDLSTSCLMRHVRRAHPTKLIQENGSLSAGSSFSP-PSLLLPPQPA--DVGDLSTVLS MYOLU110252_PE1 NOISO NEKDLSTSCLMRHVRRAHPTALIQEEGSVSTLGSISS-PALVFPPQPT--PLGDLGTVLS MYOLU143333_PE2 NOISO NEKDLSTSCLMRHVRRAHPTALIQEEGSVSTLGSISS-PALVFPPQPT--PLGDLGTVLS ORYLA23_7_PE29 NOISO ------------------------------------------------------------ PANTR22_51_PE7 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSVSAVSSFPS-PSLLLPPQPA--DAGDLSTILS PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO NEKDLSTSCLMRHVRRAHPTVLIQENGSVSAVSSFPS-PSLLLPPQPA--DAGDLSTILS RAT7_PE1614 NOISO NEKDLSTSCLMRHVRRAHPTKLIQENGSLSAGSSFSS-PSLLLPPQPA--DVGDLSTMLS RAT7_PE185 NOISO -------------------------NRNLSSGSSFSS-PSPLLPPQPA--DVGDLSTVLS TETNG19_PE312 NOISO NEKDLSTSCLMRHVRRAHPTVLLQDGADISPSHLMSSFASSLIPPIPNSPKNGDLTNSL- TURTR85811_PE1 NOISO NEKDLSTSCLMRHVRRAHPTVLVEENGSAPAPAPLPA-PLPQLPPPPT--DAGDPGTVLS XENTR20_2_PE12 ENSXETG00000014526 NEKDLSTSCLMRHVRRAHPRVLVSENGTMPGISSYSP-PTLLLPPQSL--DAAESNV--T XENTR20_2_PE13 ISOFORMIN NEKDLSTSCLMRHVRRAHPRVLVSENGTMPGISSYSP-PTLLLPPQSL--DAAESNV--T MATCH CONSENSUS NEKDLSTSCLMRHVRRAHP??L?????????????????????PP????????D??????

ANOCA447_1_PE4 NOISO PIKLVKKAASKIPSPDQITEESVPVICTEEMPSDLSHTEKSNK-EEG-GVGLSQHFPNNQ CANFA10_21_PE31 NOISO PVSLAPKLALKAPSPDDMMEESTSAVSLEETPSDAPASDKYGR-E----------VPPLP CAVPO184_1_PE35 NOISO PVSLVPDVAPKIPSPDRIKEESVSAVPPEG------VVDKFSR-EEA-PAGSSPRLPSLH CHICK1_PE251 NOISO PIKLVKKMASKIPSPDRIIEESVSIVSSEEI-ADLSVSEKCNK-EEV-MVGSSPQLPNNQ DANRE4_28_PE4 NOISO -----KSSTENHTQLSSFLVEATDMVPKESLQKVKPKGEKSVKGDS--IAVQSPHSFN-N DIPORGS_3277_PE1 NOISO PNRLVQKMAPKIPSPDRVTEESVSVVSSEEASSDVSVAEKYGR-DEA-LAGALPHLPPLH ECHTEGS_6359_PE1 NOISO ---XXXXX----------------XX----------XXXXX-X-X----------X-XXX FELCAGS_742_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX-XXXXXPPLPTLH GASACGROUPIV_21_PE16 NOISO -----ISSASKNTSPSTSSAENSDPSSKEVFPVVEPKLEPNA-NGEAGVGLSSSHSND-N GORGO22_36_PE1 NOISO PIKLVQKVASKIPSPDRITEESVSVVSSEEISSDMSVSEKCGR-EEA-LVGSSPHLPALH HS22_PE2380 NOISO PIKLVQKVASKIPSPDRITEESVSVVSSEEISSDMSVSEKCGR-EEA-LVGSSPHLPALH LOXAF176_PE11 NOISO PIKPGKTVASKIPSPDRITEESVSVVSSEEISSDMSISEKYSK-EEA-VVGSSPHLPSFN MACEUSCAFFOLD45461_PE1 NOISO PIKLVKKITAKMPSPDRVMEESGSIISSEEMSSDLSISEKCSK-EEA-LVGSSPHLPGAQ MACMU10_97_PE1 NOISO PIKLVQKVTSKIPSPDRITEESVSVVSSEEISSDMSVSEKCGR-EEA-LVGASPHLPALH MICMUGS_737_PE1 NOISO PIKLVQKMAPKIPSPDRITEESVSAVSSEEVSSDISGSEKYGR-EEA-LVGSSPHLPPLH MONDO8_8_PE4 NOISO PIKLVKKMASKIPSPDRGIEESGSVVSSEEMSSDLSISEKYNK-EEA-LVVSSPHLPSAQ MOUSE15_PE1119 ENSMUSG00000034333 PVRLVQKMAPKIPSPDQIMEESVTVVSSEELSSDVSVTEKYSR-EEA-LAGSSPNLSMLH MOUSE15_PE1120 ISOFORMIN PVRLVQKMAPKIPSPDQIMEESVTVVSSEELSSDVSVTEKYSR-EEA-LAGSSPNLSMLH MYOLU110252_PE1 NOISO PIKLVQKIASKIPSSEQVTEECGSVVSSEEV-SDVSVSEKYRQ-EEA-LVEPPQPLPTPQ MYOLU143333_PE2 NOISO PIKLVQKIASKIPSSEQVTEECGSVVSSEEV-SDVSVSEKYRQ-EEA-LVEPPQPLPTPQ ORYLA23_7_PE29 NOISO ------------------------------------------------------HSIE-N PANTR22_51_PE7 NOISO PIKLVQKVASKIPSPDRITEESVSVVSSEEISSDMSVSEKCGR-EEA-LVGSSPHLPALH PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO PIKLVQKVASKIPSPDRITEESVSVVSSEEISSDMSVSEKCGR-EEA-LVGSSPHLPALH RAT7_PE1614 NOISO PVRLVQKMAAKIPSPDQIMEESVTVVSSEEVSSDVPITEKYNR-EEA-LAGSSPNLSMLH RAT7_PE185 NOISO PVRLVQKMAAKIPSPDQIVEESVTVVSSEEVSSDVSITEKYNR-EEA-LAGSSPNPSLLH TETNG19_PE312 NOISO -----LSTASKSTSPSTSSAENSDLSSKDA-PKAEPNQDPHHKTDALGTILVSSHSSE-S TURTR85811_PE1 NOISO PGKLVPRTASKSPSPHQVTEELGSVVSSEEAPSDVSVSERYSR-DEA-LAGPPPQPPSLH XENTR20_2_PE12 ENSXETG00000014526 PAKY-KKSALKISPSEKVPEET--LTLSDEISSDFSLSGKN-K-EEV-SVVSPVSFPNSQ XENTR20_2_PE13 ISOFORMIN PAKY-KKSALKISPSEKVPEET--LTLSDEISSDFSLSGKN-K-EEV-SVVSPVSFPNSQ MATCH CONSENSUS ??????????K?????????E???????????????????????????????????????

ANOCA447_1_PE4 NOISO CEETM-ENVVEKTIQVPKGTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK CANFA10_21_PE31 NOISO CEDSA-ENGAERNPPPPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK CAVPO184_1_PE35 NOISO YDEAAADSAADRSLPLPRSVA-GSRRRSAVWKHFYLSPLDSSKAVCVHCMNEFSRGKNGK CHICK1_PE251 NOISO YDETV-ENVAEKTVVIPKNTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK DANRE4_28_PE4 NOISO HNEDATDFGTECPGSAPKSS--SSRRRSAVWKHFYLSPADSSKAVCIHCMNEFSRGKNGK DIPORGS_3277_PE1 NOISO GDEAA-ENMAERSLALPKGSS-GSRRRSAVWKHFYLSPLDSSKAVCVHCMNE-SRGKNGK ECHTEGS_6359_PE1 NOISO XXXXX----------------------------XX----XXXXX-------------XXX FELCAGS_742_PE2 NOISO CEEPS-DSGPEKTPPLPKSAS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK GASACGROUPIV_21_PE16 NOISO NLEDACDGGPERAPGTPKGSSSSSRRRSAVWKHFYLSPADNSKAVCIHCMNEFSRGKNGK GORGO22_36_PE1 NOISO YDEPA-ENLAEKSLPLPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK HS22_PE2380 NOISO YDEPA-ENLAEKSLPLPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK LOXAF176_PE11 NOISO YDDAV-ENSTEKSLTVPKSTS-GCTRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK MACEUSCAFFOLD45461_PE1 NOISO YDEAV-ENVAEKTVAVPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK MACMU10_97_PE1 NOISO YDETA-ENLAEKSLPLPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK MICMUGS_737_PE1 NOISO YDEAT-EHTAEKNLPLPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCVHCMNEFSRGKNGK MONDO8_8_PE4 NOISO YDEVV-ENVAEKTVPVPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK MOUSE15_PE1119 ENSMUSG00000034333 YDDAS-ETMADRNLSLPKSTS-GSRRRSAVWKHFYLSPLDSSKAVCVHCMNEFSRGKNGK MOUSE15_PE1120 ISOFORMIN YDDAS-ETMADRNLSLPKSTS-GSRRRSAVWKHFYLSPLDSSKAVCVHCMNEFSRGKNGK MYOLU110252_PE1 NOISO HDDSA-ESGPEKSFPLPKSTS-GSRRWSAVWKHFYLSPLDSSKAVCIHCMSEFSRGKNGK MYOLU143333_PE2 NOISO HDDSA-ESGPEKSFPLPKSTS-GSRRWSAVWKHFYLSPLDSSKAVCIHCMSEFSRGKNGK ORYLA23_7_PE29 NOISO NVEELSDGGSERLPGTPKGSN--SRRRSAVWKHFYLSPADNSKAVCIHCMNEFSRGKNGK PANTR22_51_PE7 NOISO YDEPA-ENLAEKSFPLPKSTS-GSRRRSAVWKHFYLSPLDSSKAVCIHCMNEFSRGKNGK PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO YDEPA-ENLAEKSLPLPKSTS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK RAT7_PE1614 NOISO YDDTS-ETIADRNLSLPKSTS-GSRRRSAVWKHFYLSPLDSSKAVCVHCMNEFSRGKNGK RAT7_PE185 NOISO YDDTS-ETIADRNISLPKSTS-GSRRRSAIWKHFYLSP-DSSKAVCVYCMNEFRRGKNRK TETNG19_PE312 NOISO YAEDLLDGASERPPGTPKSSS--SRRRSAVWKHFYLSPVDSSKAVCIHCMNEFSRGKNGK TURTR85811_PE1 NOISO CDEPA-ENGAEKNLPLPRSAS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK XENTR20_2_PE12 ENSXETG00000014526 LDETT-ENIVEKHIPTPKNSS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK XENTR20_2_PE13 ISOFORMIN LDETT-ENIVEKHIPTPKNSS-GSRRRSAVWKHFYLSPLDNSKAVCIHCMNEFSRGKNGK MATCH CONSENSUS ????????????????PK??S?GSRRRSAVWKHFYLSP?D?SKAVC?HCMNEFSRGKNGK

ANOCA447_1_PE4 NOISO DLGTSCLIRHMWRAHRSIVLQENGGGSSIPPLYTAPPTLLPPLLPSDG-DLISV-SSPGK CANFA10_21_PE31 NOISO DLGTSCLIRHMWRAHRSIVLQENG-GSGLPPPYAAPPTLLPALPPPDG-DPSSVSSSPGK CAVPO184_1_PE35 NOISO DLGTSCLIRHMWRAHRAVVLQENGGEG----------------------DPSSVASSPGK CHICK1_PE251 NOISO DLGTSCLIRHMWRAHRSIVLQENGGGTSIPPLYTTPPTLLPSLLPSDS-DLNSISSSPGK DANRE4_28_PE4 NOISO DLGTSCLIRHMWRAHRDIVIDENGQGSSIPPPYTTPPTLLSRTQ--D----------STD DIPORGS_3277_PE1 NOISO DLGTSCLIRHMWRAHRSIALQENGGGASIPPLYPAPPTLLPTLLPPEA-DPSSGVPSLGK ECHTEGS_6359_PE1 NOISO -----------------XXXXXXXXXXX---------------------------X---- FELCAGS_742_PE2 NOISO DLGTSCLIRHMWRAHRSIVLQENGGGPGIPPPYAAPPTLLPALPPPEG-GPGSVSSSPGT GASACGROUPIV_21_PE16 NOISO DLGTSCLIRHMWRAHKEVVIEENGLGNHIPPPYTNPPSLLSRAQLQD----------PLE GORGO22_36_PE1 NOISO DLGTSCLIRHMWRAHRAIVLQENG-GTGIPPLYSTPPTLLPSLLPPEG-ELSSVSSSPVK HS22_PE2380 NOISO DLGTSCLIRHMWRAHRAIVLQENG-GTGIPPLYSTPPTLLPSLLPPEG-ELSSVSSSPVK LOXAF176_PE11 NOISO ALGTSCLIRHMWRAHRSIVLQENGGGTGIPPLYSTPPTLVPSLQHSDG-DFNSRSSSPGK MACEUSCAFFOLD45461_PE1 NOISO DLGTSCLIRHMWRAHRSIVLQENGGGTSIPPLYSAPPTLLPSLLPSEG-DLNSVASSPGK MACMU10_97_PE1 NOISO DLGTSCLIRHMWRAHRAIVLQENG-GTGIPPLYSTPPTLLPSLLPPEG-ELSSVSSSPVK MICMUGS_737_PE1 NOISO DLGTSCLIRHMWRAHRSIVLQENG-GAGVPALYSAPPTLLPALLSPEG-DPSSTSSSPGK MONDO8_8_PE4 NOISO DLGTSCLIRHMWRAHRSIVLQENGGGTSIPPLYSAPPTLLPSLLPSEG-DLNSVSSSPGK MOUSE15_PE1119 ENSMUSG00000034333 DLGTSCLIRHMWRAHRSIVLQENGGNTGIPPLYPMPPTLLPALLPPEG-DLNSASLSPGK MOUSE15_PE1120 ISOFORMIN DLGTSCLIRHMWRAHRSIVLQENGGNTGIPPLYPMPPTLLPALLPPEG-DLNSASLSPGK MYOLU110252_PE1 NOISO DLGTSCLIRHMWRAHRAIVLQEKSEGAAITPPYSAPTTLLPALPTQEG-NPSPMSSSPGN MYOLU143333_PE2 NOISO DLGTSCLIRHMWRAHRAIVLQEKSRGASMPPPYSTPPTLLPALLPPER-DPSLVSSSPGN ORYLA23_7_PE29 NOISO DLGTSCLIRHMWRAHKEVVIEENGQGNHIPPPYTNPPSLLSRTQLLD----------SFE PANTR22_51_PE7 NOISO DLGTSCLIRHMWRAHRAIVLQENG-GTGIPPLYSAPPTLLPSLLPPEG-ELSSVSSSPVK PIG5_102_PE23 NOISO ------------------------------------------------------------ PONPY22_47_PE4 NOISO DLGTSCLIRHMWRAHRAIVLQENG-GTGIPPLYSTPPTLLPSLLPPEG-ELSSVSSSPVK RAT7_PE1614 NOISO DLGTSCLIRHMWRAHRSIVLQENGGSTGIPPLYPMPPTLLPALLPPEG-DVNSASLSPGK RAT7_PE185 NOISO DLGTSCLIRHMWRAHRSIVLQN-RASTGIPSLHPMSPTLLPALLPPEG-DLNPALLSSGN TETNG19_PE312 NOISO DLGTSCLIRHMWRAHKDVVIEENGHGNHIPPPYTNPPSLLSRTKMHE----------PLD TURTR85811_PE1 NOISO DLGTSCLIRHMWRAHRSIVLRENGGGAGVPPPYSAPPTLLPTPPPPDG-EPSPTSSSPGK XENTR20_2_PE12 ENSXETG00000014526 DLGTSCLIRHMWRAHRSIVLQENGGGTSLPPPYSVPPTLLPSLLPSDGGDVGFVAVSPGK XENTR20_2_PE13 ISOFORMIN DLGTSCLIRHMWRAHRSIVLQENGGGTSLPPPYSVPPTLLPSLLPS------------GK MATCH CONSENSUS DLGTSCLIRHMWRAHR?IVL?ENG?????PP?Y??PPTLL????????????????????

ANOCA447_1_PE4 NOISO MAKEPTSICSSPDRMTEENNSNVPLGDTLMEDS-PLLSSSE----------DVA-EASLV CANFA10_21_PE31 NOISO LVQESPSASSSPDRLTEDLQVHLHAGDTLMEDA-SALS-SD----------DVG-EASLA CAVPO184_1_PE35 NOISO PVGECPSAASSPGQLAEDLPLHAQPGDVLPEDA-SVLSSSD----------EVA-EASAV CHICK1_PE251 NOISO LMKESASVSSSPDRISEEIHTNLSSGDVLVED--SMLSSSD----------DIG-EVSFV DANRE4_28_PE4 NOISO VKKESLCTSHNPDTISDKMPNDDSENMTLEDENDATYQS-REESSID-QCLLKGESIPLS DIPORGS_3277_PE1 NOISO LVRGCPSAASSPDRLGEDPG------D-------VSVLSSD----------ELA-EASLL ECHTEGS_6359_PE1 NOISO ----------XX-------------------XXXXXXXXXX----------XXX-XXXXX FELCAGS_742_PE2 NOISO LAQESPSA--SPDRPAEDLQGRLNPGDALPEDA-SALS-SD----------DVG-EALLA GASACGROUPIV_21_PE16 NOISO VKKESPLLPSSPETAPDELAQSTEESMDIKQECEEVLNLSGQEPSLDISFKAQGEDASLS GORGO22_36_PE1 NOISO PVRESPSASSSPDRLTEDLQSHLNPGDGLMEDA-AAFSSSD----------DVG-EASAS HS22_PE2380 NOISO PVRESPSASSSPDRLTEDLQSHLNPGDGLMEDV-AAFSSSD----------DIG-EASAS LOXAF176_PE11 NOISO VVGEPTSASSSPDRLPEDVHFHFHPGETLLEDV-SLLSSSE----------DVG-DASMV MACEUSCAFFOLD45461_PE1 NOISO LVKESPSASSSPDRLVEEIHSHLNPGDALMEDV-SVLSSSD----------DVG-EASLV MACMU10_97_PE1 NOISO LVRESPSASSSPDRLTEDLQSHLNPGDGLMEDA-AALSSSD----------DVG-EASAS MICMUGS_737_PE1 NOISO PGRETPSASSSPDRLAEDLPSHLSPGDALLEAV-SVLSSSG----------DVG-EAP-A MONDO8_8_PE4 NOISO LVKESPSASSSPDRLTEEIHAHLNPGDALMEDV-SVLSSSD----------DIG-EASLV MOUSE15_PE1119 ENSMUSG00000034333 QVKESPSASSSPERLPEDLSSHTNPGDVSREDV-SMLSSSD----------DLG-EASVV MOUSE15_PE1120 ISOFORMIN QVKESPSASSSPERLPEDLSSHTNPGDVSREDV-SMLSSSD----------DLG-EASVV MYOLU110252_PE1 NOISO EVQESPLASSSPDQLTEHLQACLKPGDSLMEDA-SVLSSSD----------DVG-EASLV MYOLU143333_PE2 NOISO EVQESPSTSSSPDQLTEHLQACLKPGDSLMEDA-SVLSSSD----------DVG-EASLV ORYLA23_7_PE29 NOISO VKKESPLLPSSPETIADELPQSIEESMDIKEECEEVMQFSGQESSLNF-FKAQEEDTPLT PANTR22_51_PE7 NOISO PVRESPSASPSPDRLTEDLQSHLNPGDGLMEDA-AAFSSSD----------DVG-EASAS PIG5_102_PE23 NOISO -----------------------SPGDAPAGDA-PALSSSS----------DGG-EASLA PONPY22_47_PE4 NOISO PVRESPSASSSPDRLTEDLQSHLNPGDGLMEDA-AAFSSSD----------DVG-EASAS RAT7_PE1614 NOISO DVKEPPSASSSPDRLPEDLSSHTNPGDVSREDV-SMLSSSD----------DFG-EASVV RAT7_PE185 NOISO L--------LIPDRLPETLSSHTNPGDVSRENV-SMLLSSD----------DFG-E--VV TETNG19_PE312 NOISO IKKESPILPSSPETLTDEFPQNIEESMNIKVEPDELMHLSGQESSLSLSFKTPGEDTPVA TURTR85811_PE1 NOISO PVQDSTSAPSSPDRLAEDPPAHWNLGDTQVEDA-WALSSSS----------DVG-EASWA XENTR20_2_PE12 ENSXETG00000014526 MGKDPASIPSSPDRASVEIQCGVPNGNLIDDDDESVLHSSE----------SNT-ESLLL XENTR20_2_PE13 ISOFORMIN MGKDPASIPSSPDRASVEIQCGVPNGNLIDDDDESVLHSSE----------SNT-ESLLL MATCH CONSENSUS ?????????SSP?????????????G????????????SS???????????????E????

ANOCA447_1_PE4 NOISO SSPEK------SPLIFEHGSVFHQNKRMMRKLKSEVWHHFSLSPGDSLKVVCRHCNCMIN CANFA10_21_PE31 NOISO SSPEKPQAGGMSPSLLECGAVFQQNKKVMKRLKSEVWQHFSLAPMDSLKAVCRHCACIIS CAVPO184_1_PE35 NOISO SSPEKPRTGGLSPRRFASGAIFQQNKKAMRRLKSEVWHHFSLAPTDSLKAVCHYCSCAIS CHICK1_PE251 NOISO SSPEK-QCEGLGPLIFEPTAVFQQNKRIMKRLKSEVWHHFSLSPADSLKAVCRYCSCMIS DANRE4_28_PE4 NOISO SSPEE-HTDGHSIISEDQSSVFQQNKKIMKRVKSEVWHHFIVSPVDQLKALCRYCPCVIS DIPORGS_3277_PE1 NOISO SSLEKRPAGPVSPR-QGPGGIFQQNKKVMRRLKSEVWHHFSLAPMDSLKAVCRYCGCVIS ECHTEGS_6359_PE1 NOISO SSPEK--RDGLSQRASGPGAVFQQNKKVMKRLKSEVWHHFSLAPTDSLKAVCRHCSCVIS FELCAGS_742_PE2 NOISO SSPEKPQGDGLSPGLLESGAVFQQNKKVMKRLKSEVWHHFSLAPTDSLKAVCRHCTCVIS GASACGROUPIV_21_PE16 NOISO VSPCG-LSEGPSLD--PDHSVFQQNKMLMKRVKSEVWHHFIVSPVDQLKALCRYCPCVIS GORGO22_36_PE1 NOISO SPEKQ-QADGLSPRLFESGAIFQQNKKVMKRLKSEVWHHFSLAPMDSLKAECRYCGCAIS HS22_PE2380 NOISO SPEKQ-QADGLSPRLFESGAIFQQNKKVMKRLKSEVWHHFSLAPMDSLKAECRYCGCAIS LOXAF176_PE11 NOISO SSPEK-QGDGPSPRVFESGTVFQQNKKVMKRLKSEVWHHFSLAPLDSLKAVCRYCSCVIS MACEUSCAFFOLD45461_PE1 NOISO SSPEK-QGDGLSTLIFEPGTVFQQNKKIMKRLKSEVWHHFSLSPTDNLKAVCRYCSCMIS MACMU10_97_PE1 NOISO SPEKQ-QADGLSPRLFESGAVFQQNKKVMKRLKSEVWHHFSLAPTDSLKAECRYCGCAIS MICMUGS_737_PE1 NOISO SSPEKQPAHGLRPRTFESGAVFQQNKKVMRRLKSEVWHHFSLAPMDL--SVCRYCSCVIS MONDO8_8_PE4 NOISO SSPEK-QGDGLSTLIFEPGTVFQQNKKIMKRLKSEVWHHFSLSPTDNLKAVCRYCSCMIS MOUSE15_PE1119 ENSMUSG00000034333 SSPEKQPADTVNP-RFESGTVFQQNKKVMRRLKSEVWHHFSLAPMDSLKAVCRYCSCVIS MOUSE15_PE1120 ISOFORMIN SSPEKQPADTVNP-RFESGTVFQQNKKVMRRLKSEVWHHFSLAPMDSLKAVCRYCSCVIS MYOLU110252_PE1 NOISO SSPEKQQGDGSSPHMVESGVIFQQNQKVMKRLKSEVWHHFSLAPMDSLKAVCRHCSCVIS MYOLU143333_PE2 NOISO SSPEKQQGDGSSPHMVESGVIFQQNQKVMKRLKSEVWHHFSLAPMDSLKAVCRHCSCVIS ORYLA23_7_PE29 NOISO SSPCE-LFDGPGLS--QDHSVFQQNKKIMKRVKSEVWHHFIVSPVDQLKALCRYCPCVIS PANTR22_51_PE7 NOISO SPEKQ-QADGLSPRLFESGAIFQQNKKVMKRLKSEVWHHFSLASMDSLKAECRYCGCAIS PIG5_102_PE23 NOISO SSPEKQQGDAARPRPVEPGAVFQQNKKVMKRLKSEVWHHFSLAPTDSLKAVCRHCACVIS PONPY22_47_PE4 NOISO SPEKQ-QADGLSPRLFESGAVFQQNKKVMKRLKSEVWHHFSLAPMDSLKAECRYCGCAIS RAT7_PE1614 NOISO SSPEKRPADTVNP-RFESGTVFQQNKKVMRRLKSEVWHHFSLAPMDSLKAVCRYCSCVIS RAT7_PE185 NOISO SSPGKQPADAVNP-RSESGMVFS-NKKVMRRLKSEVWLHFSLAPMDSLKAVCQYCNCVIS TETNG19_PE312 NOISO SSPCD-LPEGPGLQ--QDHLVFQQNKKIMKRVKSEVWHHFIVSPVDQLKALCRYCPCVIS TURTR85811_PE1 NOISO SSPEKQPGDTPSPRPLESGAVFQQNKKVMRRLKSEVWHHFSLAPTDSLKAVCRHCGCVIS XENTR20_2_PE12 ENSXETG00000014526 PSPEK-LGRGRRSLTY-KPHVFQPSKKCMKRLKSEVWHHFSLSTTDNQKAVCKYCSCMIS XENTR20_2_PE13 ISOFORMIN PSPEK-LGRGRRSLTY-KPHVFQPSKKCMKRLKSEVWHHFSLSTTDNQKAVCKYCSCMIS MATCH . :* .: *:::***** ** ::. * *::* * *. CONSENSUS SSP??????????????????FQQNKK?M?RLKSEVWHHFSL?P?D?LKA?CR?C?C?IS

ANOCA447_1_PE4 NOISO RGRKGDLGTSCLTRHLYRRHPEVIGIQKSFIDVSLANSPYATLASAECSSSKLTDLPRVV CANFA10_21_PE31 NOISO RGKRGDVGTSCLMRHLYRRHPDVVSNQKGSLGAGLANSPYATLASAESSSSKLTDLPSMV CAVPO184_1_PE35 NOISO RGRKGDVGTSCLMRHLYRRHPEVVGVQKELLGASLANSPYATLASAES-SSTLSVLPATV CHICK1_PE251 NOISO RGKKGDVGTSCLMRHLYRRHPDIIGNQKSCLDVSLANSPYATLASAECSSSKLTELPTMV DANRE4_28_PE4 NOISO RGKRGDFGTSCLMRHLMRRHPDVLKTPKSTSDKVSSPQSPHSNHAAE---DLATDTLAAE DIPORGS_3277_PE1 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGGQKDLLGASLANPPYATLASAERA-SKRIDLPTAA ECHTEGS_6359_PE1 NOISO RGKKGDVGTSCLMRHLYRRHPEVIGSHRGFLGASLANSPYATLASAEGPSCKLPGMAAVV FELCAGS_742_PE2 NOISO RGKRGDVGTSCLMRHLYRRHPEVVGSQKGLLGAGLADSPYATLASAEGSSSKLTDLPATV GASACGROUPIV_21_PE16 NOISO RGKRGDFGTSCLMRHLMRRHPDVLKNQKGADEKDSSPHPYTTPPAADAVSTKETESPTSK GORGO22_36_PE1 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGSQKGFLGASLANSPYATLASAESSSSKLTDLPTVV HS22_PE2380 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGSQKGFLGASLANSPYATLASAESSSSKLTDLPTVV LOXAF176_PE11 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGNQRGFLSASLANSPYATLASAES-ASRLTDLPTMV MACEUSCAFFOLD45461_PE1 NOISO RGKKGDVGTSCLMRHLYRRHPEVIGNQKSFIDASLANSPYATLASAECSSSKLTDLPTMV MACMU10_97_PE1 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGSQKGFLGASLANSPYATLASAESSSSKLTDLPTVV MICMUGS_737_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MONDO8_8_PE4 NOISO RGKKGDVGTSCLMRHLYRRHPEVIGNQKSFIDASLANSPYATLASAECSSSKLTDLPTMV MOUSE15_PE1119 ENSMUSG00000034333 RGKKGDVGTSCLMRHLYRRHPEVVGNQKDFLGASLANSPYATLASAES-SSKLTDLPAVV MOUSE15_PE1120 ISOFORMIN RGKKGDVGTSCLMRHLYRRHPEVVGNQKDFLGASLANSPYATLASAES-SSKLTDLPAVV MYOLU110252_PE1 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGNQKGFLGASLANPPYNTLASTET-SSKLTDLPAVV MYOLU143333_PE2 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGNQKGFLGASLANPPYNTLASTET-SSKLTDLPAVV ORYLA23_7_PE29 NOISO RGKRGDFGTSCLMRHLTRRHPDVLKNQKSTDEKESPPHPYNNLATTDTVSAKETEVPVTE PANTR22_51_PE7 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGSQKGFLGASLANSPYATLASAESSSSKLTDLPTVV PIG5_102_PE23 NOISO RGRRGDVGTSCLMRHLCRRHPAVVGGQRGFLGAGLAGSPYATLASAETA-SKVTDLPTAA PONPY22_47_PE4 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGSQKGFLGASLANSPYATLASAESSSSKLTDLPTVV RAT7_PE1614 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGNQKDFLGTSLANSPYATLASAES-SSKLTDLPAAI RAT7_PE185 NOISO QGKKGDVGTSCLMRHLYRCHPEVVGNQKNFLGTSLANSPYATLASAES-CSKLTDLPAAI TETNG19_PE312 NOISO RGKRGDFGTSCLMRHLMRRHPDVLKNQKSTDEKDSSPLPYNNLAAADAVSAKETENAASE TURTR85811_PE1 NOISO RGKKGDVGTSCLMRHLYRRHPEVVGNQKGFLGASLANSPYATLASAETSSSRLTDLPTMV XENTR20_2_PE12 ENSXETG00000014526 RGKKGDLGTSCLMRHLYRRHPEVILNQKK-IDISLANSPYATLASAECS-SKMTELT-IV XENTR20_2_PE13 ISOFORMIN RGKKGDLGTSCLMRHLYRRHPEVILNQKK-IDISLANSPYATLASAECS-SKMTELT-IV MATCH CONSENSUS RGK?GD?GTSCLMRHLYRRHP?V???QK??????LA??PY?TLASAE???SK?T?LP???

ANOCA447_1_PE4 NOISO THDTQVTQVIFPISSKKTSKLWNHFSICSADSTKVICMHCGRTISRGKKPTNLGTSCLLR CANFA10_21_PE31 NOISO TKNN---QVLFPVNSKKTSKLWNHFSICSADPTKVVCLHCGRTISRGKKPTNLGTSCLLR CAVPO184_1_PE35 NOISO RKNH---QVPFPVHSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR CHICK1_PE251 NOISO THDN---QIIFPVNSKKTSKLWNHFSICSADSTKVICMHCGRTISRGKKPTNLGTSCLLR DANRE4_28_PE4 NOISO NKP-----HTLPIFSKKTSKLWNHFSISSADPTKVVCLHCSRTISRGKKTTNLGTSCLFR DIPORGS_3277_PE1 NOISO RRNR---PVLFPVSSKKTSKLWNHFG-CSADXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ECHTEGS_6359_PE1 NOISO SKDH---QVAFPVSSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR FELCAGS_742_PE2 NOISO TKHN---QVMFPIHSKKTSKLWNHFSVCSADPTKVVCLHCGRTISRGKKPTNLGTSCLLR GASACGROUPIV_21_PE16 NOISO KKP-----QTLPVFSKKTSKLWNHFSISPTDPTKVVCLHCGRTISRGKKTTNLGTSCLFR GORGO22_36_PE1 NOISO TKNN---QVMFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR HS22_PE2380 NOISO TKNN---QVMFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR LOXAF176_PE11 NOISO SKDN---QVIFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR MACEUSCAFFOLD45461_PE1 NOISO TNDN---QVIFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR MACMU10_97_PE1 NOISO TKNN---QVMFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR MICMUGS_737_PE1 NOISO XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRTISRR-KKRNLGTSCLLR MONDO8_8_PE4 NOISO SNDN---QVIFPVSSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR MOUSE15_PE1119 ENSMUSG00000034333 RKNH---QGVFPTNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR MOUSE15_PE1120 ISOFORMIN RKNH---QGVFPTNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR MYOLU110252_PE1 NOISO TKSR---PVLFPVHSKKTSKLWNHFSVCSADPTKVVCLHCGRTISRGKKPTNLGTSCLLR MYOLU143333_PE2 NOISO TKSR---PVLFPVHSKKTSKLWNHFSVCSADPTKVVCLHCGRTISRGKKPTNLGTSCLLR ORYLA23_7_PE29 NOISO AKA-----QPVPAFSKKTSKLWNHFSISPADPTKVVCLHCNRTISRGKKTTNLGTSCLFR PANTR22_51_PE7 NOISO TKNN---QVMFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR PIG5_102_PE23 NOISO AKNS---QGLFPANSKKTSKLWNHFSVCSADPTKVDCLHCGRTISRGKKPTNLGTSCLLR PONPY22_47_PE4 NOISO TKNN---QVMFPVNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR RAT7_PE1614 NOISO RKNH---QGMFPTNSKKTSKLWNHFSICSADSTKVVCLHCGRTISRGKKPTNLGTSCLLR RAT7_PE185 NOISO RKNH---QGMFPTNSKKTSKLWNHFSICSADSTKVVCLHCGRTVSRGEKPTNLGTSYLLR TETNG19_PE312 NOISO KKP-----QTPPVFSKKTSKLWNHFSISPADPTKVVCLHCSRTISRGKKTTNLGTSCLFR TURTR85811_PE1 NOISO TKNN---QVMFPVNSKKTSKLWNHFSICSADPTKVVCLHCGRTISRGKKPTNLGTSCLLR XENTR20_2_PE12 ENSXETG00000014526 NHDN---QIVFPTNSKKTSKLWNHFSICSADSTKVICMHCGRTISRGKKPTNLGTSCLLR XENTR20_2_PE13 ISOFORMIN NHDN---QIVFPTNSKKTSKLWNHFSICSADSTKVICMHCGRTISRGKKPTNLGTSCLLR MATCH CONSENSUS ??????????FP??SKKTSKLWNHFSICSAD?TKV?CLHCGRTISRGKKPTNLGTSCLLR

ANOCA447_1_PE4 NOISO HLQRFHSNVLKPDASEPVLSSSTNSHVPLNTDLLGSSSFDETSDKFSDSHPVAKKITSLI CANFA10_21_PE31 NOISO HLQRFHGSVLKPDVPRAARASSPSLRGPLSTQLSGASSFDDTNEKFYDSHPVAKKITSLI CAVPO184_1_PE35 NOISO HLQRFHGHVLKTDTPEPAMPCSATRLGPLSSELSAASSFDDAGEKLYDSHPVAKKITSLI CHICK1_PE251 NOISO HLQRFHNNVLKTDVSETVLSTSTDNHMPLSTELLASSTFDETNDKFCDSHPVAKKITSLV DANRE4_28_PE4 NOISO HMQRFHGHVLENNSNISGDGPSAETQVKQELMDISTYQ--ENAEKFSECHPAAKKITKLI DIPORGS_3277_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ECHTEGS_6359_PE1 NOISO HLQMFHSSVLRIAAAEATSPAPAGARPPLSTEPQGAPAPEEPCEKLCDSHPVARKITGLI FELCAGS_742_PE2 NOISO HLQRFHGSALKADAPRAARPSSPGLRGPLGAELSGASSLEDTAEKFYDSHPVAKKITSLI GASACGROUPIV_21_PE16 NOISO HMQRFHGHFLESNNAISGDVPSAEIHIKQELMDTSAYGAEQNPERFDEHHPVAKKITKLL GORGO22_36_PE1 NOISO HLQRFHSNVLKTEVSETARPSSPDIRVPRGTELSGASSFDDTNEKFYDSHPVAKKITSLI HS22_PE2380 NOISO HLQRFHSNVLKTEVSETARPSSPDTRVPRGTELSGASSFDDTNEKFYDSHPVAKKITSLI LOXAF176_PE11 NOISO HLQRFHGNVLKSDASETALPSSPERHMPLSTELPGASSRDDTSEKFCDSHPVAKKITSLI MACEUSCAFFOLD45461_PE1 NOISO HLQRFHSNVLKNDASETVLPSAAEIRVPLSTELLGSSSLDETNEKFSDSHPVAKKITSLV MACMU10_97_PE1 NOISO HLQRFHSNVLKTEVSETARPSSPDIRVPRGTELSGASSFDDTNEKFYDSHPVAKKITSLI MICMUGS_737_PE1 NOISO HLQRFHSNVLKTDASETARS-PPDRHATPSTESSGVSSFDDINEKFYDSHPVAKKITSLI MONDO8_8_PE4 NOISO HLQRFHSNVLKNDASETVLPSTAEIRVPLSTELLASSSFDETNEKFCDSHPVAKKITSLV MOUSE15_PE1119 ENSMUSG00000034333 HLQRFHGHVLKNDVSEATLSRSPGIRRPLGIELSGPSSFRDSTEKFYDSHPVAKKITSLI MOUSE15_PE1120 ISOFORMIN HLQRFHGHVLKNDVSEATLSRSPGIRRPLGIELSGPSSFRDSTEKFYDSHPVAKKITSLI MYOLU110252_PE1 NOISO HLQRFHGSMLKTDVPKTMLPSPPGVSVPLSAELSGASSFDNTDEKFYDSHPVAKKITSLI MYOLU143333_PE2 NOISO HLQRFHGSVLKTDVPKTMLPSPPGVSVPLSAELSGASSFDNTDEKFYDSHPVAKKITSLI ORYLA23_7_PE29 NOISO HMQRFHGHVLESNNAISGDAQDAEIHVKQEVMETSVYETEQNCERFDEEHPVAKKITKLV PANTR22_51_PE7 NOISO HLQRFHSNVLKTEVSETARPSSPDIRVPRGTELSGASSFDDTNEKFYDSHPVAKKITSLI PIG5_102_PE23 NOISO HLQRFHGSVLKPDAPRPAPSASPGLPAPLSLQPAGAASCEDTAEKLPDSHPAAKKITSLV PONPY22_47_PE4 NOISO HLQRFHSNVLKTEVSETARPSSPDIRVPRGTELSGASSFDDTNEKFYDSHPVAKKITSLI RAT7_PE1614 NOISO HLQRFHGHVLKNDVSEATLPHSPGIRRPLGMELSGASSLRDSTEKFYDSHPVAKKITSLI RAT7_PE185 NOISO HLQRFHGHVLKNDVSEATLPHSPGIRRPLGMELSGASSLRDFTEKFYDSFSCQKKKSCLI TETNG19_PE312 NOISO HLQRFHGHALESNNAISGDVPSAEIHVKQELMETSVYGTEQTCERFDDHHPVAKKITRLL TURTR85811_PE1 NOISO HLQRFHGGVLKPDAPRTAPPSPPGARGPLSSESAGASSCDDTSEKFYDSHPVAKKITSLI XENTR20_2_PE12 ENSXETG00000014526 HLQRFHSNVLQNNSVSETLR-PADSQTPVNTEL-AASSFEDTTDKFSDSHPVAKKITSLI XENTR20_2_PE13 ISOFORMIN HLQRFHSNVLQNNSVSETLR-PADSQTPVNTEL-AASSFEDTTDKFSDSHPVAKKITSLI MATCH CONSENSUS HLQRFH??VL?????????????????P???????????????EKF?DSHPVAKKIT?L?

ANOCA447_1_PE4 NOISO AEMIALDLQPFSFVDNIGFNRLLEYLQPQYSLPSPSYFSRTAIPNMYDNVKEIIVSHLKE CANFA10_21_PE31 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIVLSHLKE CAVPO184_1_PE35 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSQLKE CHICK1_PE251 NOISO AEMIALDLQPYSFVDNIGFNRLLEYLQPQYSLPSPSYFSRTAIPDMYDNVRQIIISHLKE DANRE4_28_PE4 NOISO AEMLALDLQPSTVVENVGLNRLLEYLQPQYSLPPSSYFTSTAIPEMYESVKEVVLTHLKE DIPORGS_3277_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPSPSYFSRTAIPGMYDSVKRIIMSHLKE ECHTEGS_6359_PE1 NOISO AEMMALDLQPYSVVDSVGFTRLLGYLKPQYSLPSPSYFSRSAIPGMYDSVKQVILSHLKD FELCAGS_742_PE2 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIVMSHLKE GASACGROUPIV_21_PE16 NOISO AEMLALDLQPSAMVENAGLSRLLEYLQPQYSLPLSSYFTSTAIPDMYERVKDVVLTHLKE GORGO22_36_PE1 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHLKE HS22_PE2380 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHLKE LOXAF176_PE11 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIILSHLKE MACEUSCAFFOLD45461_PE1 NOISO AEMIALDLQPYSFVDNIGFNRLLEYLQPQYSLPAPSYFSRTAIPDMYDNVKQIIVSHLKE MACMU10_97_PE1 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHLKE MICMUGS_737_PE1 NOISO AEMIALDLQPYSLVDNVGFNRLLKYLKPQYCLPSPSYFSRTAIPGMYDNVKQVIMSHLKE MONDO8_8_PE4 NOISO AEMIALDLQPYSFVDNIGFNRLLEYLQPQYSLPSPSYFSRTAIPDMYDNVKQIIVSHLKE MOUSE15_PE1119 ENSMUSG00000034333 AEMIALDLQPYSLVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSHLKE MOUSE15_PE1120 ISOFORMIN AEMIALDLQPYSLVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSHLKE MYOLU110252_PE1 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSHLKE MYOLU143333_PE2 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSHLKE ORYLA23_7_PE29 NOISO AEMLALDLQPSAVVENAGLNRLLEYLKPQYSLPPSSYFTSTAIPDMYEKVKDVVLTHLKE PANTR22_51_PE7 NOISO AEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHLKE PIG5_102_PE23 NOISO AEMIALDLQPYSVVDSVGFGRLLGHLRPQYSLPPASYFSRTAIPAMYDGVRHVVMAQLQE PONPY22_47_PE4 NOISO AEMIALDLQPYSFVDSVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHLKE RAT7_PE1614 NOISO AEMIALDLQPYSLVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSHLKE RAT7_PE185 NOISO AEMIALGLQSYSLVDNLGFNRLLEYLKPQNSLPSPPYFSRTAIPGMYDNVKEIIMSHLKE TETNG19_PE312 NOISO AEMLALDLQPSAMVENAGLSRLLEYLQPQYSLPPSSYFTSTAIPDMYERVKDAVLTHLKE TURTR85811_PE1 NOISO AEMIALDLQPYSFVDNVGFNRLLGYLKPQYSLPPPSYFSRTAIPGMYDNVKHIIMSHLQE XENTR20_2_PE12 ENSXETG00000014526 AEMIALDLQPYSFVNNVGFNRLLEYLQPQYSLPSASYFSRTAIPDMYENVKQIIVSHLKE XENTR20_2_PE13 ISOFORMIN AEMIALDLQPYSFVNNVGFNRLLEYLQPQYSLPSASYFSRTAIPDMYENVKQIIVSHLKE MATCH ** ..**: :*** **: *: ::::*:: CONSENSUS AEMIALDLQPYS?V?N?GFNRLLEYL?PQYSLP??SYFSRTAIP?MYD?VK????SHLKE

ANOCA447_1_PE4 NOISO AESGVVHFTSGIWMSNQTREYLTLTAHWVTFESRIRPQCEDYHCSALLNVSQIDCDYSGI CANFA10_21_PE31 NOISO AESGVIHFTSGIWMSNQTREYLTLTAHWVTFASSARPYCEDHHCSALLDVSQVDCDYSGN CAVPO184_1_PE35 NOISO AESGVVHFTSGIWMSNQTREYLTLTAHWVTFAPSVRPHCEDHHCSALLDVSQVDCDYSGN CHICK1_PE251 NOISO AESGVIHFTSGIWMSNQTREYLTLTAHWVTFESSLRPQCEDYHCSALLNVSQVDCDYNGI DANRE4_28_PE4 NOISO AEGGIIHFTTSVWIGSQTQEYLILTAHWVSFESQVLPQGQDFHCSALLGVASIDCDYNML DIPORGS_3277_PE1 NOISO AESGVVHFTSGIWMSSQTREYLTLTAHWVTFAPSARSHCEDHHCSALLDVSQIDCDYSGS ECHTEGS_6359_PE1 NOISO AESGVVHFTSGIWMSNQTREYLTLTAHWVTFTPSARPHPQDHHCSALLDVSQIDCDYGGN FELCAGS_742_PE2 NOISO AESGVVHFTSGIWMSNQTREYLTLTAHWVTFASSARPYREDRHCSALLDVSQVDCDYGGN GASACGROUPIV_21_PE16 NOISO AESGVVHFTTSIWVGSQTREYLTLTAHWATYESSVRPPGQDFHCSALLSVSQIDCDHDTH GORGO22_36_PE1 NOISO AESGVIHFTSGIWMSNQTREYLTLTAHWVSFESSARPRCDDHHCSALLDVSQVDCDYSGN HS22_PE2380 NOISO AESGVIHFTSGIWMSNQTREYLTLTAHWVSFESPARPRCDDHHCSALLDVSQVDCDYSGN LOXAF176_PE11 NOISO AESGVVHFTSGIWMSNQTREYLTLTAHWVTFASSVRPRREDHHCSALLDVSQIDCDYGGN MACEUSCAFFOLD45461_PE1 NOISO AESGVIHFTSGIWMSSQTREYLTLTAHWVTFESSVRPHCEDYHCSALLNVSQVDCDYSGV MACMU10_97_PE1 NOISO AESGVIHFTSGIWMSNQTREYLTLTAHWVSFESSARPRCDDHHCSALLDVSQVDCDYSGN MICMUGS_737_PE1 NOISO AESGVIHFTSGIWMSSQTREYLTLTAHWVSFESSARPRCEDHHCSALLDVSQVDCDYSGN MONDO8_8_PE4 NOISO AESGVIHFTSGIWMSSQTREYLTLTAHWVTFESSVRPHCEDYHCSALLNVSQVDCDYSGV MOUSE15_PE1119 ENSMUSG00000034333 AESGVVHFTSGIWMSSQTREYLTLTAHWVTFASAVRPHCEDHHCSALLDVSQIDCDYSGN MOUSE15_PE1120 ISOFORMIN AESGVVHFTSGIWMSSQTREYLTLTAHWVTFASAVRPHCEDHHCSALLDVSQIDCDYSGN MYOLU110252_PE1 NOISO AESGVVHFTSGIWMSNQTREYLTLTAHWVTFESSVRPHCEDHHCSALLDVSQTDSDYSGN MYOLU143333_PE2 NOISO AESGVVHFTSGIWMSNQTREYLTLTAHWVTFESSVRPHCEDHHCSALLDVSQIDCDYSGN ORYLA23_7_PE29 NOISO AEGGVVHFTTSIWVSSQTREYLTLTAHWATYESSVRPQGQDFHCSALLSVSQIDCDQDMH PANTR22_51_PE7 NOISO AESGVIHFTSGIWMSNQTREYLTLTAHWVSFESSARPRCDDHHCSALLDVSQVDCDYSGN PIG5_102_PE23 NOISO AESGVVHFTSGVWMSSQTREYLTLTAHWVTFESSARPHRQDRHCSALLDVSQVDCDYSGS PONPY22_47_PE4 NOISO AESGVIHFTSGIWMSNQTREYLTLTAHWVSFESSARPRCDDHHCSALLDVSQVDCDYSGN RAT7_PE1614 NOISO AESGVVHFTSGIWMSSQTREYLTLTAHWVTFASAVRPHCEDHHCSALLDVSQIDCDYSGN RAT7_PE185 NOISO AESGVVHFTSVILMSSQTREHLTLIAHWVTFTPTVRPHCEDHHCSVY------------- TETNG19_PE312 NOISO AEGGVVHFTTSIWVSSQTREYLTLSAHWATYESSLRPQGQDFHCSALLSVSQIDCDHDMQ TURTR85811_PE1 NOISO AESGVVHFTSGIWMSSQTREYLTLTAHWVTFESSARPHREDHHCSALLDVSQVDCDYSGG XENTR20_2_PE12 ENSXETG00000014526 AESGVIHFTAGIWMSSQTREYLTLTAHWVTFESSFRPHCENHHCSALLHVSQIDCDYNDV XENTR20_2_PE13 ISOFORMIN AESGVIHFTAGIWMSSQTREYLTLTAHWVTFESSFRPHCENHHCSALLHVSQIDCDYNDV MATCH **.*::***: : :..**:*:* * ***.:: . . :: ***. CONSENSUS AESGV?HFTSGIWMS?QTREYLTLTAHWV?F?S??RP???D?HCSALL?VSQ?DCDY???

ANOCA447_1_PE4 NOISO SIQKQLEYWWEAWIASIGLQVGITVTDNQTIEKTLNEGDHSSVQCFGHTVNLIVNEAIKS CANFA10_21_PE31 NOISO SIRKQLECWWEAWVTSTGLQIGITVTDNPSIGKTLSEGERASVQCFSHTVNLVVSEAIKS CAVPO184_1_PE35 NOISO SIQKQLECWWEAWVTSLGLQIGITVTDNPSIGKTLSEAEHSSVQCFGHTVNLIVNEAIKS CHICK1_PE251 NOISO SIQKQLEYWWEMWITSIGLQIGITVTDNHSIEKTLNEGDHSSVQCFSHTVNVIVNEAIKS DANRE4_28_PE4 NOISO NIQKQLEYLWDTWMGSSGLKIGFTVTDNQTIRNVLESCDHTTMQCFVHNIDLIVNEAIKS DIPORGS_3277_PE1 NOISO GIRRQLQCWWEAWVTSIGLRVGITVTDNPSIGKTLSEGEHSSVQCFSHTVNLIVSEAIKS ECHTEGS_6359_PE1 NOISO SIRKQLEYWWEAWVTSMGLQVGITVTDNASIGKTLSDGEHPSVQCFSHMVSLIVNEAIKS FELCAGS_742_PE2 NOISO GIRKQLECWWEAWVTSPGLQVGITVTDNPSIGKTLSEGERASVQCFSHTVDLVVGEAIKS GASACGROUPIV_21_PE16 NOISO DIPKQLEYLWESWIASSGLKRGFTVTDNTTVRNTLEDYGHATLQCFGHTIDLIVSEAIKS GORGO22_36_PE1 NOISO SIQKQLECWWEAWVTSTGLQVGITVTDNPSIGKTLSEGEHSSVQCFSHTVNLIVSEAIKS HS22_PE2380 NOISO SIQKQLECWWEAWVTSTGLQVGITVTDNASIGKTLNEGEHSSVQCFSHTVNLIVSEAIKS LOXAF176_PE11 NOISO SIQKQLEYWWEAWVTSIGLQVGITVTDNPSIGKTLNEGDHSSVQCFSHTVNLIVNEAIKS MACEUSCAFFOLD45461_PE1 NOISO SVQKQLECWWEAWVTSVGLQIGITVTDNQSIGKTLNEGEHSSVPCFGHTINLIVNEAIKS MACMU10_97_PE1 NOISO SIQKQLECWWEAWVTSTGLQVGITVTDNPSIGKTLSEGEHSSVQCFSHTVNLIVSEAIKS MICMUGS_737_PE1 NOISO SIQKQLECWWEAWVTSIGLQIGITVTDNPSIGKTLNDGEYTSVQCFSHTVNLIVSEAIKS MONDO8_8_PE4 NOISO SVQKQLEYWWEAWVTSVGLQIGITVTDNQSIGKTLNEGEHSSVPCFGHTINLIVNEAIKS MOUSE15_PE1119 ENSMUSG00000034333 SIQKQLECWWEAWVTSIGLQIGITVTDNPSIGKMLSEGEHSSVQCFSHTVNLIVSEAIKS MOUSE15_PE1120 ISOFORMIN SIQKQLECWWEAWVTSIGLQIGITVTDNPSIGKMLSEGEHSSVQCFSHTVNLIVSEAIKS MYOLU110252_PE1 NOISO SIQKQL------------------------------------------------------ MYOLU143333_PE2 NOISO SIQKQLECWWEAWVTSTGLQVGITVTDNPSIGKTLNEGEHSSVQCFSHTVNLIVNEAIKS ORYLA23_7_PE29 NOISO DIPKQLEYLWDSWITSSGLKRGFTLTDNITIQHTLEEHGHPIMECFGHTIDLIVSEAIKS PANTR22_51_PE7 NOISO SIQKQLECWWEAWVTSTGLQVGITVTDNPSIGKTLSEGEHSSVQCFSHTVNLIVSEAIKS PIG5_102_PE23 NOISO SVQKQLECWWEAWVTSAGLQVGITVTDNPSIGRTLNEGARSSVQCFSHTVSLIVGEAIKS PONPY22_47_PE4 NOISO SIQKQLECWWEAWVTSTGLQVGITVTDNPSIGKTLSEGEHSSVQCFSHTVNLIVSEAIKS RAT7_PE1614 NOISO SIQKQLECWWEAWVTSIGLQIGITVTDNPSIGKMLSEGEHSSVQCFSHTVNLIVSEAIKS RAT7_PE185 NOISO -----------------------------------------SVQCFSHTVNLILSEAIKS TETNG19_PE312 NOISO DIPKQLEYLWDSWITSSGLKKGFTVSDNAAIRHTLEDHGHVTMHCFGHTLDLIISEAIKS TURTR85811_PE1 NOISO SVQKQLECWWEAWVTSTGLQVGITVTDSPSIGKALNEGARSSVQCFSHTVSLIVSEAIKS XENTR20_2_PE12 ENSXETG00000014526 SVQKHLEYLWESWIASCGLQIGITVTDNHSIAKTLNESEHSSVQCFGHTVDLIVNEAIKS XENTR20_2_PE13 ISOFORMIN SVQKHLEYLWESWIASCGLQIGITVTDNHSIAKTLNESEHSSVQCFGHTVDLIVNEAIKS MATCH CONSENSUS ???KQLE??WE?W??S?GL??GITVTDN??I???L??????SVQCF?HT??LIV?EAIKS

ANOCA447_1_PE4 NOISO QRMVQNLLSIARKICERVHRSAKAREKLAELQKEYHLPQHLLIQDVPSKWDTSFHMLERL CANFA10_21_PE31 NOISO QRMVQNLLSIARKICERVHRSPKAKEKLAELQKEYELPQHHLIQDVPSKWNTSFHMLERL CAVPO184_1_PE35 NOISO QRMVQNLLSLARKLCERVQRSPRAREKLAELQREYELPPHPLLQDVPSRWNTSFHMLERL CHICK1_PE251 NOISO QRMVQNLLSIARKICERVHRSAKAKEKLAELQKEYELPQHQLIQDVPSKWNTSFHMLERL DANRE4_28_PE4 NOISO QRMVQNLLSIARKICERVHRSAKAKEKLAELQKVYQLPENQLVQDVPSKWKTSYFMLERL DIPORGS_3277_PE1 NOISO QRMVQNLLSTARKLCERVHRSPRAREKLAELQKEYELPPHPLIQDVPSRWSTSFHMLERL ECHTEGS_6359_PE1 NOISO QRMVQNLLSIARKLCERVHRSPKAKEKLAELQREYGLPQHHLIQDVPSKWSTSLLMLDRL FELCAGS_742_PE2 NOISO QRMVQNLLSIARKICERVHRSPKAKEKLAELQKEYALPQRHLIQDVPSRWNTSFHMLERL GASACGROUPIV_21_PE16 NOISO QRMVQNLLSIARKICERVHRSAKAKEKLAELQRLHQLPENQLIQDVPSKWRTSFFMLERL GORGO22_36_PE1 NOISO QRMVQNLLSLARKICERVHRSPKAKEKLAELQREYALPQHHLIQDVPSKWSTSFHMLERL HS22_PE2380 NOISO QRMVQNLLSLARKICERVHRSPKAKEKLAELQREYALPQHHLIQDVPSKWSTSFHMLERL LOXAF176_PE11 NOISO QRMVQNLLSIARKICERVHRSPKAKEKLAELQKEYELPQHHLIQDVPSKWNTSFHMLERL MACEUSCAFFOLD45461_PE1 NOISO QRMVQNLLSIARKICERVHRSAKAKEKLAELQKEYELPPHHLIQDVPSKWSTSFHMLERL MACMU10_97_PE1 NOISO QRMVQNLLSLARKICERVHRSPKAKEKLAELQREYALPQHHLIQDVPSKWSTSFHMLERL MICMUGS_737_PE1 NOISO QRMVQNLLSIARKVCERVQRSPRAKEKLAELQREYALPQHHLIQDVPSRWNTSFHMLERL MONDO8_8_PE4 NOISO QRMVQNLLSIARKICERVHRSAKAKEKLAELQKEYELPQHHLIQDVPSKWSTSFHMLERL MOUSE15_PE1119 ENSMUSG00000034333 QRMVQNLLSIARKLCERVHRSPRAREKLAELQKEYELPQHQLIQDVPSKWSTSFHMLERL MOUSE15_PE1120 ISOFORMIN QRMVQNLLSIARKLCERVHRSPRAREKLAELQKEYELPQHQLIQDVPSKWSTSFHMLERL MYOLU110252_PE1 NOISO ------------------------------------------------------------ MYOLU143333_PE2 NOISO QRMVQNLLSIARKLCERVLRSHAAKEKLAELQKEYELPPHHLIQDVPSKWNTSFHMLERL ORYLA23_7_PE29 NOISO QRMVQNLLSIARKICERVHRSAKAKEKLVELQRAHQLPENQLVQDVPSKWRTSFFMLERL PANTR22_51_PE7 NOISO QRMVQNLLSLARKICERVHRSPKAKEKLAELQREHALPQHHLLQDVPSKWSTSFHMLERL PIG5_102_PE23 NOISO QRLVQNLLSTARKICERVHRSPRAKAKLAELQREYALPAHPLLQDVPSKWDTSLHMLERL PONPY22_47_PE4 NOISO QRMVQNLLSLARKICERVHRSPKAKEKLAELQREYALPQHHLIQDVPSKWSTSFHMLERL RAT7_PE1614 NOISO QRMVQNLLSIARKLCERVHRSPRAREKLAELQREYELPQHQLIQDVPSKWSTSFHMLERL RAT7_PE185 NOISO QRMVQNLLSI-RKLCERVHQSPRAREKLAELQKEYELPQHQLIQDVPSKWSTSFHMLEF- TETNG19_PE312 NOISO QRMVQNLLSIARKICERVHRSAKAKEKLAELQRAHQLPENQLIQDVPSKWRTSFSMLERL TURTR85811_PE1 NOISO QRMVQNLLSTARKICERVHRSPRAKAKLAELQKEYELPPHHLLQDVPSKWNTSFHMLERL XENTR20_2_PE12 ENSXETG00000014526 QRMVQNLLSIARKICERVHRSTKAKEKLAELQKEYDLPQHHLIQDVPSKWNTSFHMLDRL XENTR20_2_PE13 ISOFORMIN QRMVQNLLSIARKICERVHRSTKAKEKLAELQKEYDLPQHHLIQDVPSKWNTSFHMLDRL MATCH CONSENSUS QRMVQNLLS?ARK?CERVHRS??A?EKLAELQ?EY?LP?H?L?QDVPSKW?TSFHMLERL

ANOCA447_1_PE4 NOISO IEQKRAIDEMSIECSFRELISCDQWEVMQSVCHALKPFEVASREMSTHMSTLSQVIPMIH CANFA10_21_PE31 NOISO IEQKRAINEMSIECNFRELISCDQWEVMQSVCHALKPFDAASREMSTHVSTLSQVIPMIH CAVPO184_1_PE35 NOISO LEQKRAINELSIECNFRELISCDQWEVMQSVCHALRPFDAASREMNTPVSTLSQVIPMIH CHICK1_PE251 NOISO IEQKRAIDEMSIECSFRELISCDQWEVMQSVCHALKPFEAASREMSTHMSTLSQVIPMIH DANRE4_28_PE4 NOISO VEQKKAIDEMSIECNFRELISCDQWEVMGSVCNALKPFVVACREMSNRTATLGQVIPLIH DIPORGS_3277_PE1 NOISO IEQKRAVNEMSVECNFRELISCDQWEVMQSVCHALRPFDTASREMSAHVSTLSQVIPMIH ECHTEGS_6359_PE1 NOISO IEQKRAVNKVSVECNFRELLSCDQWEVMQSVCHALKPFDAASREMSTHVSALSQVIPMIH FELCAGS_742_PE2 NOISO IEQKRAINEMSVECNFRELISCDQWEVMQSVCHALKPFDAASREMSAHASTLGQVIPMIH GASACGROUPIV_21_PE16 NOISO VEQKKAIDEMSIECNFREIISGDQWEVMLSICNALKPFEVACGEMSNRTATLGQVIPLVH GORGO22_36_PE1 NOISO IEQKRAINEMSVECNFRELISCDQWEVMQSVCRALKPFEAASREMSTQMSTLSQVIPMVH HS22_PE2380 NOISO IEQKRAINEMSVECNFRELISCDQWEVMQSVCRALKPFEAASREMSTQMSTLSQVIPMVH LOXAF176_PE11 NOISO IEQKRAINEMSIEYNFRELISCDQWEFMQSVCHALKPFDAASREMSTHVSALSQVIPMIH MACEUSCAFFOLD45461_PE1 NOISO IEQKRAIDEMSIECSFREQISCDQWEVMQSVCHALKPFEAASREMSTHMSTLSQVIPMIH MACMU10_97_PE1 NOISO IEQKRAINEMSVECNFRELISCDQWEVMQSVCCALKPFEAASREMSTQMSTLSQVIPMVH MICMUGS_737_PE1 NOISO VEQKRAINEMSVECNFRELISCDQWEVMQSVCHALKPFDTSRV----IGLPVNQVIPMIH MONDO8_8_PE4 NOISO IEQKRAIDEMSIECSFREQISCDQWEVMQSVCHALKPFEAASREMSTHVSTLSQVIPMIH MOUSE15_PE1119 ENSMUSG00000034333 IEQKRAVNEVSIECNFRELISCDQWEVMQSVCHVLRPFDAASREMSAHMSTLSQVIPMIH MOUSE15_PE1120 ISOFORMIN IEQKRAVNEVSIECNFRELISCDQWEVMQSVCHVLRPFDAASREMSAHMSTLSQVIPMIH MYOLU110252_PE1 NOISO ------------------------------------------------------------ MYOLU143333_PE2 NOISO IEQKRAINEMSIECNFRELISCDQWEVMKSVCHALKPFDAASREMSSHMSTLSQVIPMIH ORYLA23_7_PE29 NOISO VEQKNAIDEMSIECNFREIISCDQWEVMLSVCNALKPFEVACREMSNHTATLGQVIPLIH PANTR22_51_PE7 NOISO IEQKRAINEMSVECNFRELISCDQWEVMQSVCRALKPFEAASREMSTQMSTLSQVIPMVH PIG5_102_PE23 NOISO LEQKRAVNELSVECHFRELISCDQWEVMQSVCHALKPFDAARRELGARVSTLSQVIPMIH PONPY22_47_PE4 NOISO IEQKRAINEMSVECNFRELISCDQWEVMQSVCRALKPFEAASREMSTQMSTLSQVIPMVH RAT7_PE1614 NOISO IEQKRAVNEVSIECNFRELISCDQWEVMQSVCHVLRPFDAASREMSAHMSTLSQVIPMIH RAT7_PE185 NOISO --QKRAVNEVSIERNFRELISCDQWEVMQSVCHVLRPSDATSREMSAHVSTLSQVIPVIH TETNG19_PE312 NOISO VEQKSAIDELSIECNFREIISCDQWEVMLSVCTALKPFEVAYREMSNRTATLGQVIPLIH TURTR85811_PE1 NOISO IEQKRAVNELSVECNFRELISCDQWEVMQSVCRALKPFDAARREMSTHESTLSQVIPMIH XENTR20_2_PE12 ENSXETG00000014526 IEQKRAIDEMSIECSFRELISCDQWEVMQSVCHALKPFEAASREMSMHMATLSQVIPMIH XENTR20_2_PE13 ISOFORMIN IEQKRAIDEMSIECSFRELISCDQWEVMQSVCHALKPFEAASREMSMHMATLSQVIPMIH MATCH CONSENSUS ?EQKRA??E?S?EC?FRELISCDQWEVMQSVC?AL?PF??A?REMS????TL?QVIPM?H

ANOCA447_1_PE4 NOISO ILNRKIELLFEETMGIDTMLKSLKEAMVSRLSSTLHDPRYIFATLLDPRYKASLFTEEEA CANFA10_21_PE31 NOISO ILNRKIEMLFEETMGIDTMLKSLKEAMVSRLAATLHDPRYIFATLLDPRYKASLFSEEEA CAVPO184_1_PE35 NOISO ILSRKVEMLFTETMGIDTMLKSLKEAMASRLSATLHDPRYVFATLLDPRYKASLFTEEEA CHICK1_PE251 NOISO ILNRKIEMLFEETMGIDTMLKSLKEAMVSRLSSTLHDPRYIFATLLDPRYKTSLFTEEEA DANRE4_28_PE4 NOISO ILNRKIDMLFDETMGIDNMLKSLKEALVTRMSPTLHDPRYIWATMLDPRYKTSLFTEEEA DIPORGS_3277_PE1 NOISO ILSRKVEMLFGETMGIDTMLKSLKEAMASRLSATLHDPRYVFATLLDPRYKASLFTEEEA ECHTEGS_6359_PE1 NOISO ILNRKVEMLFEETMGIDTMLKSLKEAMVSRLSSTLHDPRYILATLLDPRYKASLFTE-EA FELCAGS_742_PE2 NOISO ILNRKIEMLFEETMGIDTMLKSLKEAMVSRLAATLHDPRYVFATLLDPRYKASLFSEEEA GASACGROUPIV_21_PE16 NOISO ILNRKIDLLFDETVGIDNMLVSLKDAMVGQMSATLHDPRYTWATMLDPRYKTSLFTEEEA GORGO22_36_PE1 NOISO ILNRKVEMLFEETMGIDTMLRSLKEAMVSRLSATLHDPRYVFATLLDPRYKASLFTEEEA HS22_PE2380 NOISO ILNRKVEMLFEETMGIDTMLRSLKEAMVSRLSATLHDPRYVFATLLDPRYKASLFTEEEA LOXAF176_PE11 NOISO ILNRKIEMLFEETMGIDTMLKSLKEAMVSRLSSTLHDPRYVFATLLDPRYKTSLFTEEEA MACEUSCAFFOLD45461_PE1 NOISO ILNRKIEMLFEETMGIDTMLKSLKEAMVSRLSSTLHDPRYIFATLLDPRYKASLFTEEEA MACMU10_97_PE1 NOISO ILNRKVEMLFEETMGIDTMLRSLKEAMVSRLSATLHDPRYVFATLLDPRYKASLFTEEET MICMUGS_737_PE1 NOISO ILTRKVEMLFGETMGIDTMLKSLKEAMVSRLAATLHDPRYVFATLLDPRYKASLFTEEEA MONDO8_8_PE4 NOISO ILNRKIEMLFEETMGIDTMLKSLKEAMVSRLSSTLHDPRYIFATLLDPRYKASLFTEEEA MOUSE15_PE1119 ENSMUSG00000034333 ILSRKVEMLFGETMGIDTMLKSLKEAMASRLSATLHDPRYIFATLLDPRYKASLFTEEEA MOUSE15_PE1120 ISOFORMIN ILSRKVEMLFGETMGIDTMLKSLKEAMASRLSATLHDPRYIFATLLDPRYKASLFTEEEA MYOLU110252_PE1 NOISO ------------------------------------------------------------ MYOLU143333_PE2 NOISO ILNRKIDMLFEETMGIDTMLKSLKEAMVSRLSATLHDPRYIFATLLDPRYKASLFSEEEA ORYLA23_7_PE29 NOISO ILSRKIDLLFDETVGIDNMLRSLKEALVSRMSATLHDQRYTWATMLDPRYKTSLFTEEEA PANTR22_51_PE7 NOISO ILNRKVEMLFEETMGIDTMLRSVKEAMV