Alignment of the gene Family HOG000143422 of HOGENOM

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Isoforms are ON
AILMEGL192492_1_3_PE30 NOISO ------------------------------------------------------------ BOVIN29_45_PE19 NOISO ------------------------------------------------------------ CALJA11_124_PE33 ENSCJAG00000018326 GPGGDHRSRSSGSRGDPGPGS-GARGRRLPPARA--ASRPEEDEGGQDLQLEGGALGSWG CALJA11_124_PE34 ISOFORMIN ------------------------------------------------------------ CANFA18_57_PE44 NOISO ------------------------------------------------------------ DANRE7_19_PE94 NOISO ------------------------------------------------------------ ECHTEGS_3623_PE2 NOISO ------------------------------------------------------------ GORGO11_63_PE17 ISOFORMIN ----------------------------------------------QDLQLEGGALGSWG GORGO11_63_PE18 ENSGGOG00000006043 -------------------------------------------SSGQDLQLEGGALGSWG HS11_PE1736 ENSG00000188070 EPGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWG LOXAF71_6_PE37 ENSLAFG00000020497 EPSGDHRSRSGGGRGWPGSTGSSARGRRLPPAGSGGGAEPEEEDSGQDLQLEGGALGSWG LOXAF71_6_PE38 ISOFORMIN ------------------------------------------------------------ MICMUGS_3764_PE4 NOISO ------------------------------------------------------------ MOUSE19_PE402 ENSMUSG00000053080 EPGGDHRSRSGGGRGGPGPAVTSARGRRLPPTAASGGTEPEEDDGGQALQLEGGALGSWG MOUSE19_PE404 ISOFORMIN ------------------------------------------------------------ MOUSE19_PE405 ISOFORMIN ------------------------------------------------------------ ORNANCONTIG3220_PE2 ENSOANG00000002940 ------------------------------------------------------------ ORNANCONTIG3220_PE3 ISOFORMIN ------------------------------------------------------------ ORYLA18_29_PE24 NOISO ------------------------------------------------------------ PIG2_8_PE2 NOISO ------------------------------------------------------------ RABITUN0019_1_PE8 NOISO ------------------------------------------------------------ RAT1_PE3421 ENSRNOG00000032042 ---------------------------------------------GQALQLEGGALGSWG RAT1_PE3422 ISOFORMIN ------------------------------------------------------------ SPETR5108_PE1 NOISO ------------------------------------------------------------ TUPGBGS_3508_PE2 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192492_1_3_PE30 NOISO ------------------------------------------------------------ BOVIN29_45_PE19 NOISO ------------------------------------------------------------ CALJA11_124_PE33 ENSCJAG00000018326 SAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPAR CALJA11_124_PE34 ISOFORMIN ------------------------------------------------------------ CANFA18_57_PE44 NOISO ------------------------------------------------------------ DANRE7_19_PE94 NOISO -----------------------------------PGRDHRRYYHEYWRSEYLMDFDPQR ECHTEGS_3623_PE2 NOISO ------------------------------------------------------------ GORGO11_63_PE17 ISOFORMIN SAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPAR GORGO11_63_PE18 ENSGGOG00000006043 SAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPAR HS11_PE1736 ENSG00000188070 SAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPAR LOXAF71_6_PE37 ENSLAFG00000020497 SAPLS-SRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPAR LOXAF71_6_PE38 ISOFORMIN ------------------------------------------------------------ MICMUGS_3764_PE4 NOISO ------------------------------------------------------------ MOUSE19_PE402 ENSMUSG00000053080 STPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFIPSR MOUSE19_PE404 ISOFORMIN ------------------------------------------------------------ MOUSE19_PE405 ISOFORMIN ------------------------------------------------------------ ORNANCONTIG3220_PE2 ENSOANG00000002940 ------------------------------------------------------------ ORNANCONTIG3220_PE3 ISOFORMIN ------------------------------------------------------------ ORYLA18_29_PE24 NOISO ------------------------------------------------------------ PIG2_8_PE2 NOISO ------------------------------------------------------------ RABITUN0019_1_PE8 NOISO ------------------------------------------------------------ RAT1_PE3421 ENSRNOG00000032042 STPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFIPSR RAT1_PE3422 ISOFORMIN ------------------------------------------------------------ SPETR5108_PE1 NOISO ------------------------------------------------------------ TUPGBGS_3508_PE2 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192492_1_3_PE30 NOISO ------------------------------------------------------------ BOVIN29_45_PE19 NOISO ------------------------------------------------------------ CALJA11_124_PE33 ENSCJAG00000018326 HGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAEG CALJA11_124_PE34 ISOFORMIN ------------------------------------------------------------ CANFA18_57_PE44 NOISO ------------------------------------------------------------ DANRE7_19_PE94 NOISO QGMICMVCGSSLATLKLSTIKRHIKQKHPYSLLWTESDKDVIRSGWENHLNRENSQQRPL ECHTEGS_3623_PE2 NOISO ------------------------------------------------------------ GORGO11_63_PE17 ISOFORMIN HGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAEG GORGO11_63_PE18 ENSGGOG00000006043 HGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAEG HS11_PE1736 ENSG00000188070 HGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAEG LOXAF71_6_PE37 ENSLAFG00000020497 HGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEADG LOXAF71_6_PE38 ISOFORMIN ------------------------------------------------------------ MICMUGS_3764_PE4 NOISO ------------------------------------------------------------ MOUSE19_PE402 ENSMUSG00000053080 HGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGAGGEAES MOUSE19_PE404 ISOFORMIN ------------------------------------------------------------ MOUSE19_PE405 ISOFORMIN ------------------------------------------------------------ ORNANCONTIG3220_PE2 ENSOANG00000002940 ------------------------------------------------------------ ORNANCONTIG3220_PE3 ISOFORMIN ------------------------------------------------------------ ORYLA18_29_PE24 NOISO ------------------------------------------------------------ PIG2_8_PE2 NOISO ------------------------------------------------------------ RABITUN0019_1_PE8 NOISO ------------------------------------------------------------ RAT1_PE3421 ENSRNOG00000032042 HGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGARGEAES RAT1_PE3422 ISOFORMIN ------------------------------------------------------------ SPETR5108_PE1 NOISO ------------------------------------------------------------ TUPGBGS_3508_PE2 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192492_1_3_PE30 NOISO ----------------------VPSLPPTLPGKAPAGEGSRC---Q-R--RGGPVAPCAR BOVIN29_45_PE19 NOISO ----------------------VPSLPPTLSGKAPAGGGSRR---Q-R--RGGPGAPRAR CALJA11_124_PE33 ENSCJAG00000018326 LGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGNANTHYGEVG---VWE--ARGPRAAAAL CALJA11_124_PE34 ISOFORMIN ----------------------VPACPPKGPGNANTHYGEVG---VWE--ARGPRAAAAL CANFA18_57_PE44 NOISO ----------------------MQACPPKGAGKAPADEGSRC---Q-Q--RGGLVAPRAR DANRE7_19_PE94 NOISO CTDPDVPPEAEEILDVDRHSTGLGSYKPIGASSPDPQ---AQAGL--SRVSPSPPAP--- ECHTEGS_3623_PE2 NOISO ------------------------------------------------------------ GORGO11_63_PE17 ISOFORMIN LGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRR---Q-R--RGGPVAPRAR GORGO11_63_PE18 ENSGGOG00000006043 LGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRR---Q-R--RGGPVAPRAR HS11_PE1736 ENSG00000188070 LGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRR---Q-R--RGGPVAPRAR LOXAF71_6_PE37 ENSLAFG00000020497 LGAQGAEEEEE-EEEEEEEGASLPACQPKGPGKAPAGGGGRR---QRR---GGPVAPRAR LOXAF71_6_PE38 ISOFORMIN ------------------------------------------------------------ MICMUGS_3764_PE4 NOISO ------------------------------------------------------------ MOUSE19_PE402 ENSMUSG00000053080 LGAQGAEEEE-EEDEEEEEGANLQACPPKGSGKAPAGGGCRR---QRRGVRGGSVAPRRR MOUSE19_PE404 ISOFORMIN ------------------------------------------------------------ MOUSE19_PE405 ISOFORMIN ------------------------------------------------------------ ORNANCONTIG3220_PE2 ENSOANG00000002940 --------------------CAAAPWPPSS--SAPSSATSAR----------NTHTPCTG ORNANCONTIG3220_PE3 ISOFORMIN ------------------------------------------------------------ ORYLA18_29_PE24 NOISO ------------------------------------------------------------ PIG2_8_PE2 NOISO ----------------------LPACPPKGPGKAPAGGGDRR---Q-R--RGGPVAPRAR RABITUN0019_1_PE8 NOISO ----------------------LQACPPKGPGNAPNMVAGAGAGSAGYKVDGGDMQ--GD RAT1_PE3421 ENSRNOG00000032042 LGARGAEEEEEEEDEEEEEGANLQACPPKGSGKAPAGGGCRR---QRRGVRGGPVAPRRR RAT1_PE3422 ISOFORMIN ----------------------LQACPPKGSGKAPAGGGCRR---QRRGVRGGPVAPRRR SPETR5108_PE1 NOISO ------------------------------------------------------------ TUPGBGS_3508_PE2 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192492_1_3_PE30 NOISO RRRLSASRRAGGSRGLGARGLGARRLERRLKESLQNWFRAECLMDYD------------- BOVIN29_45_PE19 NOISO RGCLSASRRAGGSRGL-----GARRLERRLKESLQNWFRAECLMDYD------------- CALJA11_124_PE33 ENSCJAG00000018326 PPRSWCSRATHCSFSG-----GQKRMGKGWPSSLQNWF-AECLMDYDPRG-RLVCMACGR CALJA11_124_PE34 ISOFORMIN PPRSWCSRATHCSFSG-----LGLCIA----L---------------------------- CANFA18_57_PE44 NOISO CRGLSASRRAGDSRGL-----GARQLDRRLKESLQNWFRAECLMDYD------------- DANRE7_19_PE94 NOISO ------------SVQELSPGPTAQVMERYLNDSLHAWFRQEFLMEYQAEQGRLVCMVCSC ECHTEGS_3623_PE2 NOISO -------------------------------------------MDYDPWGNRLVCMACGR GORGO11_63_PE17 ISOFORMIN RLRLSASRRAGGSRGL-----GARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGR GORGO11_63_PE18 ENSGGOG00000006043 RLRLSASRRAGGSRGL-----GARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGR HS11_PE1736 ENSG00000188070 RLRLSASRRAGGSRGL-----GARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGR LOXAF71_6_PE37 ENSLAFG00000020497 --R-RASRRAGGSRGL-----GARRLDRRLKESLQNWFRAECLMDYDPRGNRLVCMACGR LOXAF71_6_PE38 ISOFORMIN -------------------------------------------MDYDPRGNRLVCMACGR MICMUGS_3764_PE4 NOISO -------------------------------------------MDYDPRGNRLVCMACGR MOUSE19_PE402 ENSMUSG00000053080 --RLAASRRAGGSRGL-----GARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGR MOUSE19_PE404 ISOFORMIN -------------------------------------------MDYDPRGNRLVCMACGR MOUSE19_PE405 ISOFORMIN -------------------------------------------MDYDPRGNRLVCMACGR ORNANCONTIG3220_PE2 ENSOANG00000002940 APARRRSSAAAGTLIWGRRARGGQSLERQLKES--------------------------- ORNANCONTIG3220_PE3 ISOFORMIN ------------------------------------------------------------ ORYLA18_29_PE24 NOISO -------------------------------------------MEYEAEAGRLLCMVCGA PIG2_8_PE2 NOISO RRRLSASRRAGGSRGL-----GPRRLERRLKESLQNWFRAECLMDYD------------- RABITUN0019_1_PE8 NOISO RLGPLGLRRPGGSRGL-----GAPRLERTLKESLQNWFRAECLMDYG------------- RAT1_PE3421 ENSRNOG00000032042 --RLAASRRAGGSRGL-----GARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGR RAT1_PE3422 ISOFORMIN --RLAASRRAGGSRGL-----GARRLERRLKESLQNWFRAEWIF---------------- SPETR5108_PE1 NOISO ------------------------------------------------------------ TUPGBGS_3508_PE2 NOISO -------------------------------------------MD-YPRGNWLVCMACGQ MATCH CONSENSUS ???????????????????????????????????????????M????????????????

AILMEGL192492_1_3_PE30 NOISO --------------------------------------------------------LVPQ BOVIN29_45_PE19 NOISO ------------------------------------------------------DDLVPQ CALJA11_124_PE33 ENSCJAG00000018326 ALPSLHLDDIRAHVLEVHPGSLGLSGPQRSALLQAWGGQPEAL--SELTQSPPGDDLAPQ CALJA11_124_PE34 ISOFORMIN -------------------------------IIQRWGRTVGTG-SRAECLMDYGDDLAPQ CANFA18_57_PE44 NOISO --------------------------------------------------------LVPQ DANRE7_19_PE94 NOISO LLPSLHLDHIKSHMLELHPNSLLYSAEEKHAILQTWAKMHSEAFLNYLTESHPLQPQIKL ECHTEGS_3623_PE2 NOISO ALPSLHLDDIRAHVLEAHPSSLGLSGPQRSALLQAWDSQPEVL--P---EPPPDDNLVPQ GORGO11_63_PE17 ISOFORMIN ALPSLHLDDIRAHVLEVHPGSLGLSGPQRSALLQAWGGQPEAL--SELTQSPPGDDLAPQ GORGO11_63_PE18 ENSGGOG00000006043 ALPSLHLDDIRAHVLEVHPGSLGLSGPQRSALLQAWGGQPEAL--SELTQSPPGDDLAPQ HS11_PE1736 ENSG00000188070 ALPSLHLDDIRAHVLEVHPGSLGLSGPQRSALLQAWGGQPEAL--SELTQSPPGDDLAPQ LOXAF71_6_PE37 ENSLAFG00000020497 ALPSLHLDDIRAHVLEVHPSSLGLSGPQRSALLQAWGGQSEVL--PELTQPPPDDNLVPQ LOXAF71_6_PE38 ISOFORMIN ALPSLHLDDIRAHVLEVHPSSLGLSGPQRSALLQAWGGQSEVL--PELTQPPPDDNLVPQ MICMUGS_3764_PE4 NOISO ALPSLHLDDIRAHVLEVHPSSLGLSGPQRSALLQAWGGQPAAL--SELTQSPADDDLVPQ MOUSE19_PE402 ENSMUSG00000053080 ALPSLHLDDIRAHVLEVHPSSLGLSGPQRSALLQAWGDQPEAL--SELTQPSPDDDLVPQ MOUSE19_PE404 ISOFORMIN ALPSLHLDDIRAHVLEVHPSSLGLSGPQRSALLQAWGDQPEAL--SELTQPSPDDDLVPQ MOUSE19_PE405 ISOFORMIN ALPSLHLDDIRAHVLEVHPSSLGLSGPQRSALLQAWGDQPEAL--SELTQPSPDDDLVPQ ORNANCONTIG3220_PE2 ENSOANG00000002940 --------------------------------------------------LQTDDDVAPQ ORNANCONTIG3220_PE3 ISOFORMIN -----------------------------------------------------DDDVAPQ ORYLA18_29_PE24 NOISO ELPSLHLDHIKSHVLDTHPVSLLYSSEEKHCVLQAWAHAHAVAFVFHVAEESENS--VKS PIG2_8_PE2 NOISO ------------------------------------------------------DDLVPQ RABITUN0019_1_PE8 NOISO ------------------------------------------------------DDLAPR RAT1_PE3421 ENSRNOG00000032042 ALPSLHLDDIRAHVLEVHPSSLGLSGPQRSALLQAWGDQPEAL--SELTPPSPDDDLVPQ RAT1_PE3422 ISOFORMIN -----------------------------------------------------DDDLVPQ SPETR5108_PE1 NOISO ------------------------------------------------------EDLVPQ TUPGBGS_3508_PE2 NOISO ALPSLHLEDIHAHVLEVHPSSLGLSGSQRSALLQAWGGQSEAL--SELTQPS-DDDLIPQ MATCH CONSENSUS ??????????????????????????????????????????????????????D?L?PQ

AILMEGL192492_1_3_PE30 NOISO DL--TRKSRDPAPP-----AQDLRPPD--VKKEEAGWVPERP-GPAGA-----EAEEGQR BOVIN29_45_PE19 NOISO DL--TSKSRDPAPAAGAQSSQDLSLPD---VKEEAGWVPERVPGPAGEE----EPEEGER CALJA11_124_PE33 ENSCJAG00000018326 DL--TRKSRDSASAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEE-EEELEEGEGER CALJA11_124_PE34 ISOFORMIN DL--TRKSRDSASAAGAPSSQDLSPPD---VKEEAGWVPERP-GP--------------- CANFA18_57_PE44 NOISO DL--TRKSLDPAPTAGALSSRDLSPPGPGVKKEEAVWVPERPR-PAEEE----ELEEGEG DANRE7_19_PE94 NOISO EQHTKEINLDGAASFFPPI----MDPVQGNL---------------ESYTRGDENPSDTV ECHTEGS_3623_PE2 NOISO DL--TRKCQDSAPAARAPSSQDLSPPD---VKEEAGWAPESP-RPAVEEE--EEGGQGER GORGO11_63_PE17 ISOFORMIN DL--TGKSRDSASAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEEEEEELEEGEGER GORGO11_63_PE18 ENSGGOG00000006043 DL--TGKSRDSASAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEEEEEELEEGEGER HS11_PE1736 ENSG00000188070 DL--TGKSRDSASAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEE-EEELEEGEGER LOXAF71_6_PE37 ENSLAFG00000020497 DL--TRKSQDSAPAARAPSSRDLSPPD---VKEEAAWVPESP-GPAEEEE---EQEEGER LOXAF71_6_PE38 ISOFORMIN DL--TRKSQDSAPAARAPSSRDLSPPD---VKEEAAWVPESP-GPAEEEE---EQEEGER MICMUGS_3764_PE4 NOISO DL--TRKSRDSAPAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAE--EEELEEGEGER MOUSE19_PE402 ENSMUSG00000053080 DL--TRKSRDSAPAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEEE---EGEGEGER MOUSE19_PE404 ISOFORMIN DL--TRKSRDSAPAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEEE---EGEGEGER MOUSE19_PE405 ISOFORMIN DL--TRKSRDSAPAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEEE---EGEGEGER ORNANCONTIG3220_PE2 ENSOANG00000002940 DL--SSKAHGLVPPSDAPSPPEPSASG---ADRELGWVSGSPRG---------------- ORNANCONTIG3220_PE3 ISOFORMIN DL--SSKAHGLVPPSDAPSPPEPSASG---ADRELGWVSGSPRVKEEEEEE------EKG ORYLA18_29_PE24 NOISO EHNTKGKTMDVCAESLKTTQTDSDVPPQGVGTST-----------QDICLIGEDGG---- PIG2_8_PE2 NOISO DL--TRKSRDSASAAGAPSSQDLSPPD---VKEEAGWVPERP-GLAEEEEL----EEGER RABITUN0019_1_PE8 NOISO DL--TRKSRHSA------SSQDLSPPD---VKEEAGWAPERP-GPAEEALEEE----GEG RAT1_PE3421 ENSRNOG00000032042 DL--TRKSRDSAPAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEEEA-EEGEGEGER RAT1_PE3422 ISOFORMIN DL--TRKSRDSAPAAGAPSSQDLSPPD---VKEEAGWVPERP-GPAEEEA-EEGEGEGER SPETR5108_PE1 NOISO DL--TRKSRDSAPAAGAPSSQDLSPPD---VKEEAGRVPERP-GPTERA----EEGEAER TUPGBGS_3508_PE2 NOISO DL--TRKSQD-APAAGAPSSQDLSPPD---VKEEAGWVSERP-GPAEEQ-----ENEGER MATCH : . . CONSENSUS DL??T?KS?D?A????APSS?DLSPPD????KEEAGWVPE?P?GP???????????????

AILMEGL192492_1_3_PE30 NOISO VGAPGRSPRGXX------XXX--RLEYLVELDG-GRRGLVCMVCGGALASLKMSTVKRHI BOVIN29_45_PE19 NOISO VGVPGRSARGRDPRRYCPERW--RLEYLLELDG-GRRGLVCLACGGALASLKMSTIKRHI CALJA11_124_PE33 ENSCJAG00000018326 AGVPGRSLRGRTHRRHPQERW--RLEYLMELDG-GRRGLVCGVCGGSLASLKMSTIERHI CALJA11_124_PE34 ISOFORMIN --VPGRSLRGRTHRRHPQERW--RLEYLMELDG-GRRGLVCGVCGGSLASLKMSTIERHI CANFA18_57_PE44 NOISO VGVPGRSPRGR--RRRCRERW--RPEYLVELDG-GRRGLVCLACGGALASLQMSTVQRHI DANRE7_19_PE94 NOISO QRSQSLPYYPRKRRLKYGSPWRLRLDYLVAYGPPENPLCYCMVCSEHLPVPRVTNFRKHI ECHTEGS_3623_PE2 NOISO AGVPGRPPRGRDHRRHYQERW--RLEYLMEFDG-GRRGLVCMVCGGALASLKMSTIKRHI GORGO11_63_PE17 ISOFORMIN AGVPGRSPRGRAHRRHPQERW--RLEYLMELDG-GRRGLVCGVCGGALASLKMSTIERHI GORGO11_63_PE18 ENSGGOG00000006043 AGVPGRSPRGRAHRRHPQERW--RLEYLMELDG-GRRGLVCGVCGGALASLKMSTIERHI HS11_PE1736 ENSG00000188070 AGVPGRSPRGRAHRRHPQERW--RLEYLMELDG-GRRGLVCGVCGGALASLKMSTIERHI LOXAF71_6_PE37 ENSLAFG00000020497 AGVPGRQPRGRDHRRHYQERW--RLEYLMEFDG-GRRGLVCMVCGGALASLKMSTIKRHI LOXAF71_6_PE38 ISOFORMIN AGVPGRQPRGRDHRRHYQERW--RLEYLMEFDG-GRRGLVCMVCGGALASLKMSTIKRHI MICMUGS_3764_PE4 NOISO VGVPGGSPRGRDHRRHYQERW--RLEYLMELDG-GRRGLVCMVCGGALASLKMSTIKRHI MOUSE19_PE402 ENSMUSG00000053080 EGIPNRPRRGRDHRRHYQERW--RLEYLMELDG-CRRGLVCMVCGGALASLKMSTIKRHI MOUSE19_PE404 ISOFORMIN EGIPNRPRRGRDHRRHYQERW--RLEYLMELDG-CRRGLVCMVCGGALASLKMSTIKRHI MOUSE19_PE405 ISOFORMIN EGIPNRPRRGRDHRRHYQERW--RLEYLMELDG-CRRGLVCMVCGGALASLKMSTIKRHI ORNANCONTIG3220_PE2 ENSOANG00000002940 --ASPSVPRGRDHRRYYQERW--RLEYLMDYDG-GRRGLVCMVCGGVLATLKVSTIKRHI ORNANCONTIG3220_PE3 ISOFORMIN AWASPSVPRGRDHRRYYQERW--RLEYLMDYDG-GRRGLVCMVCGGVLATLKVSTIKRHI ORYLA18_29_PE24 NOISO VGAPLQEPPPKRRRLQVGNPWRLRLDYLVAYGPQG-QGTFCMVCSQVLRETKVSSFRQHI PIG2_8_PE2 NOISO VGVQDRAPRGRDQRRHYRERW--RLEYLMELDG-GRRGLVCMVCGGALASLKMSTIKRHI RABITUN0019_1_PE8 NOISO EGL--------GGRRRRQERW--RLEYLLELDG-GRRGLVCLACGGALASLKMSTIQRHI RAT1_PE3421 ENSRNOG00000032042 AGIPGRPRRGRDHRRHYQERW--RLEYLMELDG-CRRGLVCMVCGGALASLKMSTIKRHI RAT1_PE3422 ISOFORMIN AGIPGRPRRGRDHRRHYQERW--RLEYLMELDG-CRRGLVCMVCGGALASLKMSTIKRHI SPETR5108_PE1 NOISO EGVPGQSLRGGDHRPHYQERW--RLEYLMELDG-GRRGLVCLVCGGALASLKMSTIKRHI TUPGBGS_3508_PE2 NOISO AGVPGRLS---RNRRHYQERW--GLEYLVELDG-AQRGLVCMVCGGTLASLKRSTIKRHI MATCH :**: . * .*. * : :...:** CONSENSUS ?G?P????RGR??RR???ERW??RLEYL?E?DG??RRGLVC?VCGG?LASLKMSTI?RHI

AILMEGL192492_1_3_PE30 NOISO RQRHPGSTRLSGPVKALIAQEWSEKAAHLLALGLPSPESPRDPAAPGTA--AASEEG--- BOVIN29_45_PE19 NOISO RRRHPGSARLGGPVGALIAQEWSEKAAHLLAMGLPCPESPGDPAAPSTA--AASEEG--- CALJA11_124_PE33 ENSCJAG00000018326 RRRHPGSTRLGGPLQALIAREWSEKAAHLLALGLPRPESPRGRAAPGTA--AASEEG--- CALJA11_124_PE34 ISOFORMIN RRRHPGSTRLGGPLQALIAREWSEKAAHLLALGLPRPESPRGRAAPGTA--AASEQG--- CANFA18_57_PE44 NOISO RQRHPGSTRLRGPVQALIAREWSEKAAHLPALGLPGPEPPGNPAAPATA--AASEEG--- DANRE7_19_PE94 NOISO QECHPETSSLSRSERDAVVNAWMKEENIDRAT--PKED--GAYSKLPLLLFKASKNN--- ECHTEGS_3623_PE2 NOISO RQRHPGSTRLSGPVKALIAQEWSEKAAHLLALGLPSPESPRDPAAPSTA--SASERG--- GORGO11_63_PE17 ISOFORMIN RRRHPGSTRLGGPVQALIAREWSEKAAHLLALGLPRPESPQGPVAPGTA--AASEEG--- GORGO11_63_PE18 ENSGGOG00000006043 RRRHPGSTRLGGPVQALIAREWSEKAAHLLALGLPRPESPQGPVAPGTA--AASEEG--- HS11_PE1736 ENSG00000188070 RRRHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESPQGPIPPGTA--AASDEG--- LOXAF71_6_PE37 ENSLAFG00000020497 RQRHPGSTRLSGP-KALIAQEWSEKAAHLLALGLPCPES--------------------- LOXAF71_6_PE38 ISOFORMIN RQRHPGSTRLSGP-KALIAQEWSEKAAHLLALGLPCPESPPEGGYGGE-------AQ--- MICMUGS_3764_PE4 NOISO RRRHPGSTRLSGPVKARIAQEWSEKAAHLLALGLPCPASPRGPAALGTA--AASEEG--- MOUSE19_PE402 ENSMUSG00000053080 RQRHPGSNSLSGPVKALIAQEWSEKAAHLLALGLPRPESPSVPVAPSTA--SASEEG--- MOUSE19_PE404 ISOFORMIN RQRHPGSNSLSGPVKALIAQEWSEKAAHLLALGLPRPESPSVPVAPSTA--SASEEG--- MOUSE19_PE405 ISOFORMIN RQRHPGSNSLSGPVKALIAQEWSEKAAHLLALGLPRPESPSVPVAPSTA--SASEEG--- ORNANCONTIG3220_PE2 ENSOANG00000002940 HQRHPGSTQLSGPVKALIAQEWSRQAARLLALGPPFCELSGGAGGDVVT--AATTLSGVS ORNANCONTIG3220_PE3 ISOFORMIN HQRHPGSTQLSGPVKALIAQEWSRQAARLLALGPPFCELSGGAGGDVVT--AATTLQGDG ORYLA18_29_PE24 NOISO QEHHPETTALSRQEREAMAAAWTKDSSEDPSP--ADKIPPGGGSALS----N-------- PIG2_8_PE2 NOISO RQRHPGSTRLSGPVKALIAQEWSDKAAHLLALGLPCPESPRDPAAPSIA--AASEEG--- RABITUN0019_1_PE8 NOISO RRRHPGSSRLGGPAQALVAQECSEKAARLLASGLRCPESPRGPAAPRTA--AASEEG--- RAT1_PE3421 ENSRNOG00000032042 RQRHPGSNSLSGPVKALIAQEWSEKAAHLLGLGLPRPESPSGPVAPSTA--SASEEG--- RAT1_PE3422 ISOFORMIN RQRHPGSNSLSGPVKALIAQEWSEKAAHLLGLGLPRPESPSGPVAPSTA--SASEEG--- SPETR5108_PE1 NOISO RQRHPGSTCLTGPVK-----EWSEKAAHLLALGLPCSEPPPGPTGPSTA----ASEG--- TUPGBGS_3508_PE2 NOISO RRRHPGSTCLSGPVKALVAQEWSEKAAHLLALGLPLPEFSQGLAAPSTA--AASEKG--- MATCH :. ** : * . . CONSENSUS R?RHPGS??L?GP??ALIA?EWSEKAAHLLALGLP?PE?P????????????A???????

AILMEGL192492_1_3_PE30 NOISO GGDEEEEPE--EEWW--GDVPLSPGEPSERPAEDEEDDEDGQXXX-QRARRPLP---PPP BOVIN29_45_PE19 NOISO GGAEKEQPEEEEEWW--GDVPLSPGEPSERQAEEEEDDEDGPDPG-ALAFPPPP---PPP CALJA11_124_PE33 ENSCJAG00000018326 GGEEEEEPE--EEAW--GDVPPSPGAPLERPAEEEEDEEDGQEPG-GLVPPPP------P CALJA11_124_PE34 ISOFORMIN SGAAGQEGT--GGWG--SDVPPSPGAPLERPAEEEEDEEDGQEPG-GLV----------- CANFA18_57_PE44 NOISO GGEEEEE---EEEWW--GDAPLSPGEPSERPPEDDDDDEDGPEPG-GLAFPPLP---PPP DANRE7_19_PE94 NOISO ----YVDPQ---------SVP-VTTEPQASPVK---SIEQGGEAEDNSTQITL----QTQ ECHTEGS_3623_PE2 NOISO GAEEEPEEE--AEDR--GDVPLSPEPTERSAEEEDDDEEEE------------------- GORGO11_63_PE17 ISOFORMIN GGDEEEEPEEEEEEW--GDVPLSPGASLERPAEEEEDLQ--------------------- GORGO11_63_PE18 ENSGGOG00000006043 GGDEEEEPEEEEEEW--GDVPLSPGASLERPAEEEEDXXXXVAGS-QLTLHDC------D HS11_PE1736 ENSG00000188070 GGDEEEEPEEEEEEW--GDVPLSPGAPLERPAEEEEDEEDGQEPG-GLALPPP------P LOXAF71_6_PE37 ENSLAFG00000020497 ----SNPAL--CPSP--GDVPLSPEERSERPAEEEEDEEDGAEPE-ELAFPPLPPQQPPP LOXAF71_6_PE38 ISOFORMIN GPAVSNPAL--CPSP--GDVPLSPEERSERPAEEEEDEEDGAEPE-ELAFPPLPPQQPPP MICMUGS_3764_PE4 NOISO GGDEEEP---EEEWG--GDVPLPPGAPLERPPEEKEDNDDGQEPG-GFVLRPRP---P-- MOUSE19_PE402 ENSMUSG00000053080 GGAEEAEPE--EEWW--GDAPLSPGAPSERPAEEEDDEDDSQEPG-GLAFPPLPL--PPP MOUSE19_PE404 ISOFORMIN GGAEEAEPE--EEWW--GDAPLSPGAPSERPAEEEDDEDDSQEPG-GLAFPPLPL--PPP MOUSE19_PE405 ISOFORMIN GGAEEAEPE--EEWW--GDAPLSPGAPSERPAEEEDDEDDSQEPG-GLAFPPLPL--PPP ORNANCONTIG3220_PE2 ENSOANG00000002940 LGRGRTAAQGRSHGW--GPEL--EASALDYPAISPDPRLSSEEPA-GLS---LPVRAPPP ORNANCONTIG3220_PE3 ISOFORMIN E----EEAEEEEEKW--ADPR--LSS--EEPAGEEEEEEQEEEEE-SLS---LPVRAPPP ORYLA18_29_PE24 NOISO -----AAPT---------AEP-PPRDVRARTKRRKEGSASGGKG---KWKDAG----SSG PIG2_8_PE2 NOISO GGEEEEEPEEEEEWWALGDVPLSPGEPSERPAEEEDDDEDGPEPG-GLAFPPLP---PPP RABITUN0019_1_PE8 NOISO GGEEEKQPE--EEWW--GEQPPLPAVPGPQPAAFAEQGTDGQEEAPSLPYPPRPE----- RAT1_PE3421 ENSRNOG00000032042 GGAEEAEPE--EEWW--GDAPLSPGAPSERPAEEE-DEDDSQEPR-GLPFPPPPL--PPP RAT1_PE3422 ISOFORMIN GGAEEAEPE--EEWW--GDAPLSPGAPSERPAEEE-DEDDSQEPR-GLPFPPPPL--PPP SPETR5108_PE1 NOISO GRAEGAEPE--EEWW--GEVPLSPGAALERPAEEEEDEEDGQEPG-GLAFPPLPL--PPP TUPGBGS_3508_PE2 NOISO GGA-EEEPE--EEWW--GDVPLSPGAPLEPPAEEEEDEEDSQDPG-GLAFPPLPP--PPP MATCH CONSENSUS ?????????????????GD?P??P????E?PAE???D???????????????????????

AILMEGL192492_1_3_PE30 NOISO LLPRPPGPRS-------------------------------------------------- BOVIN29_45_PE19 NOISO -PPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV CALJA11_124_PE33 ENSCJAG00000018326 PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV CALJA11_124_PE34 ISOFORMIN ----------WEQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV CANFA18_57_PE44 NOISO --PPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV DANRE7_19_PE94 NOISO TAGRHRHYPGKDQRRNYQPRWKMDFLMDYDCRKHGLICMVCGATLATLKVSTIKRHILQV ECHTEGS_3623_PE2 NOISO ------------------------------------------------------------ GORGO11_63_PE17 ISOFORMIN ----HAPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV GORGO11_63_PE18 ENSGGOG00000006043 YLSSMRPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV HS11_PE1736 ENSG00000188070 PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV LOXAF71_6_PE37 ENSLAFG00000020497 PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV LOXAF71_6_PE38 ISOFORMIN PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV MICMUGS_3764_PE4 NOISO --PPRRRPRSREKRRNYQ------------------------------------------ MOUSE19_PE402 ENSMUSG00000053080 PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV MOUSE19_PE404 ISOFORMIN PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV MOUSE19_PE405 ISOFORMIN PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV ORNANCONTIG3220_PE2 ENSOANG00000002940 PPPQPLTPRSREQRRYYQPRWRSEYLMDYDGGRRGLVCMVCGGALATLKVSTIKRHILQV ORNANCONTIG3220_PE3 ISOFORMIN PPPQPLTPRSREQRRYYQPRWRSEYLMDYDGGRRGLVCMVCGGALATLKVSTIKRHILQV ORYLA18_29_PE24 NOISO LAPRHGHYPGKDQRRNYQMRWRMEYLMDYDCKRHGLICMVCGANLATLKVSTIKRHIQQV PIG2_8_PE2 NOISO PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLRVSTIQRHILQV RABITUN0019_1_PE8 NOISO --PKVQVPQAQSPRR--------------------------------------------- RAT1_PE3421 ENSRNOG00000032042 P--PPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV RAT1_PE3422 ISOFORMIN P--PPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV SPETR5108_PE1 NOISO PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRRLVCMVCGGALATLKVSTIKRHILQV TUPGBGS_3508_PE2 NOISO PPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQV MATCH CONSENSUS ???????PRS?EQRRNYQPRWR?EYLMDYD??R?GL?CMVCG??LATLKVSTIKRHILQV

AILMEGL192492_1_3_PE30 NOISO -------------------------------------------------------- BOVIN29_45_PE19 NOISO HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAPAAPRDGGADL-KAGAVCRA CALJA11_124_PE33 ENSCJAG00000018326 HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APREGGADL-KSGAVCRA CALJA11_124_PE34 ISOFORMIN HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APREGGADL-KSGAVCRA CANFA18_57_PE44 NOISO HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDGGADL-KAGAVCRA DANRE7_19_PE94 NOISO HPHSLDYSPEERQLVLLCYNQ----------------------------------- ECHTEGS_3623_PE2 NOISO -------------------------------------------------------- GORGO11_63_PE17 ISOFORMIN HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDGGADL-KSGAVCRA GORGO11_63_PE18 ENSGGOG00000006043 HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDGGADL-KSGAVCRA HS11_PE1736 ENSG00000188070 HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDGGADL-KSGAVCRA LOXAF71_6_PE37 ENSLAFG00000020497 HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDSSADL-KPGAVCRA LOXAF71_6_PE38 ISOFORMIN HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDSSADL-KPGAVCRA MICMUGS_3764_PE4 NOISO -------------------------------------------------------- MOUSE19_PE402 ENSMUSG00000053080 HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDSGADL-KPGAVCRA MOUSE19_PE404 ISOFORMIN HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDSGADL-KPGAVCRA MOUSE19_PE405 ISOFORMIN HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDSGADL-KPGAVCRA ORNANCONTIG3220_PE2 ENSOANG00000002940 HPFSLEFSPQERQTILEAYEEAALRCYGQEGFRGPVQSPGREAEVKAGGGGAICKV ORNANCONTIG3220_PE3 ISOFORMIN HPFSLEFSPQERQTILEAYEEAALRCYGQEGFRGPVQSPGREAEVKAGGGGAICKV ORYLA18_29_PE24 NOISO HAHSLYYSAEEKQQAELRYTQSGL-------------------------------- PIG2_8_PE2 NOISO HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDGGADL-KAGAVCRA RABITUN0019_1_PE8 NOISO -------------------------------------------------------- RAT1_PE3421 ENSRNOG00000032042 HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDSGADL-KPGAVCRA RAT1_PE3422 ISOFORMIN HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDSGADL-KPGAVCRA SPETR5108_PE1 NOISO HPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAP-APRDGGTDL-KPGAVCRA TUPGBGS_3508_PE2 NOISO HPFSMDFTPDERQTILEAYEEAALRCYGHEGFGPPAP-APRDGGADL-KPGAVCRA MATCH CONSENSUS HP?S????P?ERQ??L??Y????L????????????????????????????????


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