Alignment of the gene Family HOG000154674 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL193246_1_PE3 NOISO AEFLDDQDTQLCDNCKKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMEGHMATEHCQVTCKCNKKLEKRQLKKHEETDCPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGNC BOVIN17_66_PE12 ENSBTAG00000008761 AEFLNDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKCDMETHMATEHCQVTCKCNKKLEKRQLKKHEVSFPVPYYRAACRAESQSCGVFVLRQHQ-AHCLTRGRICVLC BOVIN17_66_PE13 ISOFORMIN AEFLNDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKCDMETHMATEHCQVTCKCNKKLEKRQLKKHEIYVCNVC-MCVCVYVCVYVYVYILNEHKHIHQLINPNNCSVI CALJA9_108_PE25 NOISO AEFLDDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMETHMAAEHCQVTCKCNKELEKRLLKKHEETECPLR-LAVCQHCDLELSILKLKEHE-DYCGARTELCGNC CANFA26_14_PE4 ENSCAFG00000008830 AEFLDDQDTQLCDNCKKEIPVFNFTIHEIHCQRNIGMCPVCKEPFPKSDMESHMATEHCQVTCKCNKKLEKRQLKKHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGSC CANFA26_14_PE5 ISOFORMIN AEFLDDQDTQLCDNCKKEIPVFNFTIHEIHCQRNIGMCPVCKEPFPKSDMESHMATEHCQVTCKCNKKLEKRQLKKHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGSC CAVPO115_4_PE9 NOISO AEFLDDQDTRLCGNCKKEIPVFNFTIHEIHCQRNIGVCPICKEPFPKSDMETHMTAEHCQVTCKCNKKFEKMQLKKHEETECPLR-LAVCQHCDLELSVLKLKEHE-DYCGARTELCSSC CHICK15_PE212 ENSGALG00000004802 MAAVTEVQTQLCGNCKKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLR-PAVCQHCDIQLTFNKLQDHE-SYCGARTEMCSGC CHOHOGS_3501_PE1 NOISO AEFMHDQDTQLCDNCKKEIPVFNFTIHEIHCQRNIGICPVCKEPFPKSDMESHMATEHCQVICKCNKKLEKRQLKKHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGSC DASNOGS_3144_PE1 NOISO AEFLHNQDTQLCDNCKKEIPVFNFTIHEIHCHRNIGMCLVCKEPFPKSDMETHVATEHCQVTCKCNKKLEKRQLKKHEETECPLR-LAVCQHCDLELSVLKLKDHE-DYCGARTELCGSC DIPORGS_2952_PE1 NOISO ---------------SKEIPVFNFTIHEIHCQRNIGVCPICKEPFPKSEMEIHMATEHSQXXXXXXXXXXXXXXXXXXETDCPLR-LALCQHCDLELAVLKLKEHE-EYCGARTEPCGSC ECHTEGS_3767_PE1 NOISO AEFLDDQDTRLCDNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXETECPLR-PALCQHCDLELSVLRLKEHE-DYCGARTERCGNC FELCAGS_2104_PE1 NOISO -----------------------------------------------------------------NRKLEKRQL-KHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGNC GORGO12_117_PE5 NOISO AEFLDDQETRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPTCKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLR-LAVCQHCDLELSILKLKEHE-DYCGARTELCGNC HORSE8_21_PE5 NOISO AEFLEDQSTQLCDNCKKDIPVINFTIHELHCRRNIGMCPVCKEPFPKSDMETHMATEHCQVTCKCNKKLEKRQLKKHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGTC HS12_PE2264 ENSG00000135148 AEFLDDQETRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPTCKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLR-LAVCQHCDLELSILKLKEHE-DYCGARTELCGNC HS12_PE2265 ISOFORMIN AEFLDDQETRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPTCKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLR-LAVCQHCDLELSILKLKEHE-DYCGARTELCGNC LAMPAGS_432_PE5 NOISO ---------------KKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMETHMATEHCQVTCKCNKKLEKRQLKKHEEIECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGNC LOXAF84_7_PE20 NOISO AEFLDDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKCDMETHMATEHCQVTCKCNKKLEKRQLKTHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGSC MACEUGS_4452_PE1 NOISO ---------------KREIPMPNFTIHEIHCRRNIGMCHVCKEPVPKSEMKAHVELEHSQVACKCNMKMERRQLTNHE--ECPLR-LAVCQHCELELAFLKLKDHE-DYCGARTELCGKC MACMU11_117_PE5 NOISO AEFLDDQETRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLR-LAVCQHCDLELSILKLKEHE-DYCGARTELCGNC MICMUGS_1957_PE1 NOISO ---------------KKEIPVFNFTIHEIHCQRNIGMCPVCKEPFPKSDMETHMATEHCQVTCKCNKKLEKRQLKKHEETECPLR-LALCQHCDLELSILKLKEHE-DYCGARTELCGTC MONDO3_509_PE7 ISOFORMIN AISKYICSCFVCFCSKREIPTPNFTIHEIHCRRNIGMCHICKEPVPKSEMKTHMESEHSQVTCKCNMKMERRQLTNHEALECPLR-LAVCQHCELELAFLKLKDHE-DYCGARTELCGKC MONDO3_509_PE8 ISOFORMIN -ISKYICSCFVCFCSKREIPTPNFTIHEIHCRRNIGMCHICKEPVPKSEMKTHMESEHSQVTCKCNMKMERRQLTNHEALECPLR-LAVCQHCELELAFLKLKDHE-DYCGARTELCGKC MONDO3_509_PE9 ENSMODG00000002929 -ISKYICSCFVCFCSKREIPTPNFTIHEIHCRRNIGMCHICKEPVPKSEMKTHMESEHSQVTCKCNMKMERRQLTNHEALECPLR-LAVCQHCELELAFLKLKDHE-DYCGARTELCGKC MOUSE5_PE2224 ENSMUSG00000042726 AEFRDDQASRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHMAAEHCQVTCKCNKKLEKRQLKQHAETECPLR-LAVCQHCDLELSVVKLKEHE-DYCGARTELCGSC MOUSE5_PE2225 ISOFORMIN AEFRDDQASRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHMAAEHCQVTCKCNKKLEKRQLKQHAETECPLR-LAVCQHCDLELSVVKLKEHE-DYCGARTELCGSC MYOLUGS_5807_PE3 NOISO AEFLDDQDTQLCDNCKREIPLCNFTIHEIHCQRNIGVCPICKEPFPKSGMETHMATEHCQVTCKCNKKLEKRQLQNHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGNC OCHPRGS_607_1_PE4 NOISO AEFPDNQDTRLCNNCKKEIPVFNFTIHEIHCQRNIGVCPVCTEPFPKSDMETHMAEEHCQVTCKCNKKLERRLLKQHEETECPLR-LAVCQHCDLELCVLKLKEHE-EYCGARTELCGSC ORNAN2_2_PE13 ENSOANG00000004805 MAEVGEQETQLCDNCKREIPVPNFTIHEIHCRRNLGICHICKEPIPKSEMKNHMELEHTQVTCKCNMKLEKWQLKNHEDLECPLR-LVVCQHCELELSFVKVKDHE-DYCGARTELCRGC ORNAN2_2_PE14 ISOFORMIN MAEVGEQETQLCDNCKREIPVPNFTIHEIHCRRNLGICHICKEPIPKSEMKNHMELEHTQVTCKCNMKLEKWQLKNHEDLECPLR-LVVCQHCELELSFVKVKDHE-DYCGARTELCRGC ORNAN2_2_PE15 ISOFORMIN MAEVGEQETQLCDNCKREIPVPNFTIHEIHCRRNLGICHICKEPIPKSEMKNHMELEHTQVTCKCNMKLEKWQLKNHEDLECPLR-LVVCQHCELELSFVKVKDHE-DYCGARTELCRGC PANTR12_118_PE6 NOISO AEFLDDQETRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPTCKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLR-LAVCQHCDLELSILKLKEHE-DYCGARTELCGNC PIG14_41_PE16 NOISO --FLTFSLIYF--CSKKEIPVFNFTIHEIHCQRNIGMCAICKEPFPKSDMETHMATEHCQVTCKCNKKLEKRQLKKHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGSC PONPY12_119_PE4 NOISO AEFLDDQEIRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLR-LAVCQHCDLELSILKLKEHE-DYCGARTELCGNC PROCAGS_3263_PE1 NOISO AEFQDDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMETHMATEHCQVTCKCNKKLEKRQLKTHEETECPLR-LALCQHCDLELSILKLKDHE-DYCGARTELCGSC PTEVAGS_3824_PE4 NOISO AEFLDDQDTRLCDNCKKEIPACNFTIHEIHCLRNIGMCPVCKEPFPKSDMETHMATEHCQVTCKCNKKLEKRHLKNHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGSC RABIT21_9_PE5 NOISO AELLDDQDTQLCNNCKKEIPVFNFTIHEIHCQRNIGVCPVCTEPFPKSDMETHVATEHCQVTCKCNKKLERRQLKKHEESECPLR-LAVCQHCDLELSVLKLKEHE-DYCGARTELCGSC RAT12_PE720 NOISO AEFPDDQAARLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHVATEHCQVTCKCNKKLEKRQLKQHVETECPLR-LAVCQHCDLELSVVKLKEHE-DYCGARTELCGSC SORAR140962_PE1 NOISO ------------------------------------------------------------------------------EAECPLR-PARCQHCELELAVVRLQEHE-EYCGARTELCGTC SPETRGS_2491_PE1 NOISO ------------------------------------------------------------------------------ETECPLR-LAVCQHCDLELSVLKLKEHE-DYCGARTELCGNC TARSY42503_PE1 NOISO ------------------------------------------------------------------------------ETECPLR-LALCQHCDLELSILKLKEHE-DYCGARTELCGNC TUPGBGS_5528_PE3 NOISO AEFLQDQDTRLCDNCQKEIPVFNFTIHEIHCQRNIDMCPICKEPFPKSDMETHMASEHCQVTCKCNKKLEKRQLKNHAETECPLR-LALCQHCDLELSILKLKEHE-DYCGARTELCGSC TURTRGS_415_PE5 NOISO AEFLDGQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMETHMATEHCQVTCKCNKKLEKRQLKKHEETECPLR-LALCQHCDLELSVLKLKDHE-DYCGARTELCGNC MATCH * . :.:*: : . . * CONSENSUS ???????????????K?EIP??NFTIHEIHC?RN?G?C??CKEP?PKS?M??H???EH?QVTCKCN?K?E???L??H???ECPLR?LA?CQHC?LEL???KLK?HE?DYCGARTELCG?C

AILMEGL193246_1_PE3 NOISO G-RNVLVKDLKTHPEVCGRDGEEKRDEVAMPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDLFHS----R--TTNQRNMTAQFPIQNNLLEEQERQERNRTRRPP BOVIN17_66_PE12 ENSBTAG00000008761 IGRGILHH-LTTSPYICMSNISSKGKEKA--MAPHSSTLAWKIDLAAVA-AAVRQYSCLENPMDGGACPTGSLVHGIFQA---R---IQNTCKMHSTVPVSYPSVEEQERQERNRSRQTP BOVIN17_66_PE13 ISOFORMIN LKEQKIKPVLYTNVQIKKVSVFLKDNHFSSLPGSSKGKLVWGGGSDKHM-GIA--LLLLF------APGLGWLILGSFEF---NSFSSQNSFLRTSCCLFFPPSVEEQERQERNRSRQTP CALJA9_108_PE25 NOISO G-RNVLVKDLKTHPEVCGREGEEKRNEVAIPSNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPGRPLRAFESDVFHN----R--TTNQRNITSQVSIQNNLFEEQERQERNRGRQPP CANFA26_14_PE4 ENSCAFG00000008830 G-RNVLVKDLKTHPEVCGRFGEEKKDEVAVPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRIPRRPMRAFESDLFHS----R--TTNQRNMTAQFPIQNNLLEEQERQEKNRTRQAS CANFA26_14_PE5 ISOFORMIN G-RNVLVKDLKTHPEVCGRFGEEKKDEVAVPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRIPRRPMRAFESDLFHS----R--TTNQRNMTAQFPIQNNLLEEQERQEKNRTRQAS CAVPO115_4_PE9 NOISO G-RNVLVKDLKTHPAVCGRGEEESRNQAAGAPAAC--DESRGQDGMWAASQLLRHIEALDPPTRLPRRPLRAFESDLFHN----R--TANQRNVTARFPVQNNLLVEEQMQEKDRGQKLP CHICK15_PE212 ENSGALG00000004802 G-LNIMVKDLKEHPQVCGKEAKRVSKTVP--H--F-----EGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQLE--RNKNIN CHOHOGS_3501_PE1 NOISO G-RNILVKDLKTHPAVCGREGEEKRNEVVIPPDAY--DESWSQDGIWIASHLLRQIEALNSPMRLPRRHLQSFESDLFQS----R--TTNQRNVTSQFPIQNNLXXXXXXXXXXXXXXXX DASNOGS_3144_PE1 NOISO G-RNVLVKDLKTHLEVCGREGEEKRDEVAMPPDAY--DESWNQDGIWIASQLLRQIEALDPPMRLPQRHLRSFESDLLHN----R--TTTQRNVTSQFPIQNNLFEEQEMQERNRSHQPP DIPORGS_2952_PE1 NOISO G-RNVLVKDLKTHPAVCGREEVEKRNTTAMSPNAY--DEAWGQDRIWIASQLLRQIESLDPPVRLSSRPLRSLESDSVHS----R--TSSQRNVPAHFPIQNNLFEEQERQERNRSQQPP ECHTEGS_3767_PE1 NOISO G-RNVLVKDLKTHPGVCGQEGKEKEDPVALPPNAA--ADPWGQHGMWIASHLFRQMEALDPPMRLPRRPLQCFDAELLHS----R--TTNQRNMATQFPIQNNLXXXXXXXXXXXXXXXX FELCAGS_2104_PE1 NOISO G-RNVLVKDLKTHPEVCGRDGEEKRDEVAMPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFDLDLFHS----R--TTNQRNMTAHFPIQNNLLEEQERQERNRTRQPP GORGO12_117_PE5 NOISO G-RNVLVKDLKTHPEVCGREGEEKRNEVAIPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDVFHN----R--TTNQRNITAQVSIQNNLFEEQERQERNRGQQPP HORSE8_21_PE5 NOISO G-RNVLVKDLKTHPEVCGRDEEEKKDEADVPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDLFRN----R--TTSQRSTTAPFLVQNNLLEEQERQERNRSRQPR HS12_PE2264 ENSG00000135148 G-RNVLVKDLKTHPEVCGREGEEKRNEVAIPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDVFHN----R--TTNQRNITAQVSIQNNLFEEQERQERNRGQQPP HS12_PE2265 ISOFORMIN G-RNVLVKDLKTHPEVCGREGEEKRNEVAIPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDVFHN----R--TTNQRNITAQVSIQNNLFEEQERQERNRGQQPP LAMPAGS_432_PE5 NOISO G-RNVLVKDLKTHPDVCGRDGQEKRDEVAMPSNAY--DESWGQDGIWIASQL-RQMEALDPPIRLPRRPLRAFESDLFHT----R--TTNQRSVTARFPIQNNLLEEQERQERNRSRRTP LOXAF84_7_PE20 NOISO G-RNVLVKDRKTHPEVCGKDGEEKREVVALPPNAD--DELWRQDGMWTASHL-RQIDALVPPMRLPRRHLRSFESDLVHS----R--TTSQRNMPTQFPIQNNLLEEQERQERNRSRQPP MACEUGS_4452_PE1 NOISO G-RNIMVKDLKTHPEVCGREAEEKREARTRPLHGY---EGT-RDGAWFIAQV-FRMLGPENPTKPLRRPSRSFEK--------------------------------QERRTGSKNQLYP MACMU11_117_PE5 NOISO G-RNVLVKDLKTHPEVCGREGEEKRNEVAIPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPQRPLRAFESDVFHD----R--TTNQRNITAQVSIQNNLFEEQERQERNRGQQPP MICMUGS_1957_PE1 NOISO G-RNVLVKDLKTHPEVCGRDGEEKRNEVAIPPNAY--DESWGQDGIWIASQLLRQIETLDPPMRLPRRPLRAFESDLFHN----R--TTNQRNMAAQFPIQNNLMLPS------------ MONDO3_509_PE7 ISOFORMIN G-RNVMVKDLQAHPEVCGREGEEKRESRSRPSHGY---E------TWFIAQTVQNLLGPENPTRPLRRLSRSLENPFYSHLIVDQMARNPNRGAGSAMQLDQNRGEEQERQKGNKSKRSP MONDO3_509_PE8 ISOFORMIN G-RNVMVKDLQAHPEVCGREGEEKRESRSRPSHGY---E------TWFIAQTVQNLLGPENPTRPLRRLSRSLENPFYSHLIVDQMARNPNRGAGSAMQLDQNRGEEQERQKGNKSKRSP MONDO3_509_PE9 ENSMODG00000002929 G-RNVMVKDLQAHPEVCGREGEEKRESRSRPSHGY---E------TWFIAQTVQNLLGPENPTRPLRRLSRSLENPFYSHLIVDQMARNPNRGAGSAMQLDQNRGEEQERQKGNKSKRSP MOUSE5_PE2224 ENSMUSG00000042726 G-RNVLVKELKTHPEVCGRVEEEKRTEAAIPPEAY--DEPWSQDRIWIASQLLRQIEALDPPMRLPGRPLQAFEADPFYS----R--TTSQRSMAAQFPVQNNLFEEQERQERNRSRQSP MOUSE5_PE2225 ISOFORMIN G-RNVLVKELKTHPEVCGRVEEEKRTEAAIPPEAY--DEPWSQDRIWIASQLLRQIEALDPPMRLPGRPLQAFEADPFYS----R--TTSQRSMAAQFPVQNNLFEEQERQERNRSRQSP MYOLUGS_5807_PE3 NOISO G-RNVLVKDLKTHPEVCRRDGEKKRDEAAVPPNAY--DVSWGQDGIWIASQLLRQIESLDPPMRLPRRPLRASESELSHS----R--TTNQRNMTTQFPIQNNLLEEQERQERNRSQQSP OCHPRGS_607_1_PE4 NOISO G-RNVLVKDLKTHPDVCGREGEEKRNDVAVSPHAYDYDAAFGQDGMWVASQLLRQIEALEPPVRIPRRPLRDFGSDLFHN----R--TANQRNVSTQFPIQNNLFEEQQRQERNRSRQPL ORNAN2_2_PE13 ENSOANG00000004805 G-RNVMVKDLKAHPEVCGKEEEEKREARSRPRPNY---ENEGADEAWFVSQTIKNLLGPEDPTRPLRRLPRPLENRFCSHLSVDEFFRSANRRNVSAVPVDQNLADEQGRLERNKTNLPS ORNAN2_2_PE14 ISOFORMIN G-RNVMVKDLKAHPEVCGKEEEEKREARSRPRPNY---ENEGADEAWFVSQTIKNLLGPEDPTRPLRRLPRPLENRFCSHLSVDEFFRSANRRNVSAVPVDQNLADEQGRLERNKTNLPS ORNAN2_2_PE15 ISOFORMIN G-RNVMVKDLKAHPEVCGKEEEEKREARSRPRPNY---ENEGADEAWFVSQTIKNLLGPEDPTRPLRRLPRPLENRFCSHLSVDEFFRSANRRNVSAVPVDQNLADEQGRLERNKTNLPS PANTR12_118_PE6 NOISO G-RNVLVKDLKTHPEVCGREGEEKRNEVAIPSNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDVFHN----R--TTNQRNITAQVSIQNNLFEEQERQERNRGQQPP PIG14_41_PE16 NOISO G-RNVLVKDLKTHPEVCGRNEEEKRDEVTMLPNAY--DDSWGQDGIWIASQL-RQIEALDPPMRLPRRPLRAFESDLFQS----R--TTSQRSVTAQFPIQNNLLEEQESQERNRRRQTP PONPY12_119_PE4 NOISO G-RNVLVKDLKTHPEVCGREGEEKRNEVAIPPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDVFHS----R--TTNQRNITAQVSIQNNLFEEQERQERNRGQQPP PROCAGS_3263_PE1 NOISO G-RNVLVKDLKTHPEVCGREGEEKRDAGAPPPNAD--AEPWGADGMWMASHLLRHMEALDPPTRLPRRRPRSFESDLIHS----R--TASQRNMTTQFPIQNNLLEEQERQERNRGRQPP PTEVAGS_3824_PE4 NOISO G-RNVLVKDLKTHPEVCGRDGEEKRD-VAVPLNAY--DESWGD-EIWIASQL-RQIESLSP-MR--LRRLRTFESDFSLS----R--TTNQRSMTTQFPIQNNLLEEQERQERNRSRQPS RABIT21_9_PE5 NOISO G-RNVLVKDLKTHPDICGREGEEKRNEVAIPPQAY--DESFDQDGIWIASQLLRQIEALDPPVRIPRRPLRDFGSDFFHN----R--TTNQRNMPPQFPIQNNLFEEQERQERNRSRQPL RAT12_PE720 NOISO G-RNVLVKELQTHPAVCGRVEEEKRSEAAVPPEAY--DEPWSQDRIWIASQLLRQIEALDPPMRLPGRPLRAFEADPFYS----R--TASQRGVTAHFPIQNNLFEEQERQERNRSHQSP SORAR140962_PE1 NOISO G-RNVLVKDLKAHPAVCGQAGEAKRAEAPPSPDTY--DAPWAQDGIWIASQLLRQIEALDPPTRLSRRPLRDFESDLFHG---G---TPERRDVGSQFPGHSGRXXXXXXXXXXXXRQPG SPETRGS_2491_PE1 NOISO G-RNVLVKDLKSHPEVCGRGEEERRNEVTVSPNAY--DESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDLFHN----R--TANQRNMTAPFPIQNNLFEEQERQERNRSRQPP TARSY42503_PE1 NOISO G-RNVLVKDLKTHPEVCGREGEEKRNEIAIPSNAY--DESWGQDGVWIASQLLRQIEALDT----PRRPMGAFESDLFHS---NR--IISQRNMTAQFPVQNNLFEEQERQERNRGRQPH TUPGBGS_5528_PE3 NOISO G-RNILVKDLKTHPEVCGREAEEKRNEVAIPPNAY--DEPWGQDGIWIASQLLRQIEALDPPMRLPGTPLRTFDSDLFHN----R--TTNQRNMTTQFPIQNNLXXXXXXXXXXXXXXXX TURTRGS_415_PE5 NOISO G-RNVLVKDLKTHPEVCGRDVEEKRDEVAMPPNAY--DDSWGQDGIWIASQL-RQIEALDPPMRLPRRPLRAFESELFQS----R--TTNQRSMTAQFPIQNNLLEEQERQERNRSRQTL MATCH : : CONSENSUS G?RNV?VKDLK?HP?VCG???EEKR?????????Y????????D??W?ASQ??R????L??P?R???R??R??E?????????????????R??????????NL??EQ?????N??????

AILMEGL193246_1_PE3 NOISO KEGGEDNANLDFMLALSLQNEGQARSV----AEQDFWRAVCGADQSV-EGSNALNDMKGAADRTMLPCEFCEELYPEELLIDHQTSCNPSCALPSLSMGNTSPKGV-E-----DPDVIFQ BOVIN17_66_PE12 ENSBTAG00000008761 KERGEDSANLDFMLALSLQNEGQAPTL----AEQDFWRVIYEADQSR-EGPSALNDIRGAVDETMLPCEFCEELYPEELLIDHQTSCNPSCALPPLSVGSTSPRGV-E-----DPDAIFQ BOVIN17_66_PE13 ISOFORMIN KERGEDSANLDFMLALSLQNEGQAPTL----AEQDFWRVIYEADQSR-EGPSALNDIRGAVDETMLPCEFCEELYPEELLIDHQTSCNPSCALPPLSVGSTSPRGV-E-----DPDAIFQ CALJA9_108_PE25 NOISO KEGGEDSANLDFMLALSLQNEGQASSM----AEQDFWRAVCEADQSH-GGPSSLSDIKGAADETMLPCEFCEELYPEELLIDHQTSCNPSRALPSFTTGSSSPRGV-E-----EPDVIFQ CANFA26_14_PE4 ENSCAFG00000008830 KEGGEDSANLDFMLALSLQNEGQARSV----AEQDFWRAVCGAEQSF-EGSSALNDMKGAADRTMLPCEFCEELYPEELLIDHQTSCNPSCALPSLNMGSTSPRGV-E-----DPDVIFQ CANFA26_14_PE5 ISOFORMIN KEGGEDSANLDFMLALSLQNEGQARSV----AEQDFWRAVCGAEQSF-EGSSALNDMKGAADRTMLPCEFCEELYPEELLIDHQTSCNPSCALPSLNMGSTSPRGV-E-----DPDVIFQ CAVPO115_4_PE9 NOISO PKGGEDTANLDFMLALSLQNEGQTPSV----AEQDFWRAVCEADPCH-GVAQFRSDAKGTADETMLPCEFCEELYPEELLIDHQTSCNRSRALPLLSTGSSPPRRV-E-----DPDVVFQ CHICK15_PE212 ENSGALG00000004802 SLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKENSFQ--LNSLE--QYKGDEIMLPCEFCEELYPAEDLILHQTGCNPASAFASFSKRGSLDPQKYD-----DLHNIG- CHOHOGS_3501_PE1 NOISO XXXXXXXXXXXXXXXXXXX-XXXXXSN----VVESFWTAICEADQPH-GGPSALSDIKGAAEETMLPCEFCEELYPEELLIDHQTSCNPSCALPLLSTGSSSPRGV-E-----DPDVIFQ DASNOGS_3144_PE1 NOISO KEGGEDSANLDFMLALSLQNEGQVSNM----AEQSFWRTICEADQPH-GGPSALNDLKGEADETMLPCEFCEELYPEELLIDHQTSCNPSRALPLLSTGSSSLRGV-E-----DPDVIFQ DIPORGS_2952_PE1 NOISO TKSGEDSANLDFMLALSLQSEGQASSL----AEQDFWQAVCEAEQLH-SGPGSLIDRKGAADETMLPCEFCEELYPEDLLIDHQTSCNPSRALPSLGPDSSSSSRV-E-----DPGDLFQ ECHTEGS_3767_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXX-XXXXXXXXXXXAAGETLLPCEFCEELYPEELLIDHQTSCNPSCALPPFSTGRSSPKVM-E-----RPDNVFQ FELCAGS_2104_PE1 NOISO KEGGEDSANLDFMLALSLQNEGQAHSM----AEQDFWRAVCGADQSL-EGPNALNDIKGTADRTMLPCEFCEELYPEKLXXXXXTSCNPSCALPSLSMGSTPPKEV-E-----DPDVIFQ GORGO12_117_PE5 NOISO KEGGEESANLDFMLALSLQNEGQASSV----AEQDFWRAVCEADQSH-GGPRSLSDIKGAADEIMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGV-E-----EPDVIFQ HORSE8_21_PE5 NOISO KEVGEDSADLDFMLALSLQNEGQAPRV----AEQDFWRSIWEADQSR-GGPSTLNDIKGAADDTMLPCEFCEELYPEELLIDHQTSCNPSCALPSLNVGSPSPKGV-E-----DPDVIFQ HS12_PE2264 ENSG00000135148 KEGGEESANLDFMLALSLQNEGQASSV----AEQDFWRAVCEADQSH-GGPRSLSDIKGAADEIMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGV-E-----EPDVIFQ HS12_PE2265 ISOFORMIN KEGGEESANLDFMLALSLQNEGQASSV----AEQDFWRAVCEADQSH-GGPRSLSDIKGAADEIMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGV-E-----EPDVIFQ LAMPAGS_432_PE5 NOISO KEGGEDSANLDFMLALSLQNEGQAPSM----AEQDFWRVICEADQSR-EGPNALDDIRGAADETMLPCEFCEELYPEDLLIDHQTSCNPPCALPPLSVGRTSPKGV-E-----DPEVIFQ LOXAF84_7_PE20 NOISO KEGGEDSANLDFMLALSLQNEGQAPHM----AEQDFWRAVCEADQSR-GGPRALSDIKGAAGETMLPCEFCEELYPEELLIDHQTSCNPSCALPPLSTGSSPLKVV-E-----DPDVIFQ MACEUGS_4452_PE1 NOISO PGPGEEDAHLDYMLALSLQSESSAPAA-----QQDFWRAVYT---------------EDAANETMLPCEFCEELYPEEDLILHQTGCNPTSAVASFSKRSSPPRGPG-------GPEVNF MACMU11_117_PE5 NOISO KEGGEDSANLDFMLALSLQNEGQASSV----AEQDFWRAVCEADQSH-GGPSSLSDIKGAADETMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGV-E-----EHDVIFQ MICMUGS_1957_PE1 NOISO -----------------LGLEILASST----AQQDFWRAVYEADQSH-GGPSSLSDIKXXXXXXXXXXXXXXXXXXXXXXXXXXTSCNPSCALPSFNTGSSSPRGV-E-----EPDVIFQ MONDO3_509_PE7 ISOFORMIN TVSGEEDAHLDYMLALSLQSESSVPSG-ATTHLEDFWRAVSCLDPWMVQ-PSGAQANQGSDNETMLPCEFCEELYPEEDLILHQTGCNPASALASFGKRSSPPSLSQDRGDRENHEDQFQ MONDO3_509_PE8 ISOFORMIN TVSGEEDAHLDYMLALSLQSESSVPSG-ATTHLEDFWRAVCAEDLGPTG-NRSVSCYLFADNETMLPCEFCEELYPEEDLILHQTGCNPASALASFGKRSSPPSLSQDRGDRENHEDQFQ MONDO3_509_PE9 ENSMODG00000002929 TVSGEEDAHLDYMLALSLQSESSVPSG-ATTHLEDFWRAVCAEDLATEG-PNELKKIILCVDETMLPCEFCEELYPEEDLILHQTGCNPASALASFGKRSSPPSLSQDRGDRENHEDQFQ MOUSE5_PE2224 ENSMUSG00000042726 KDSAENNAHLDFMLALSLQNEGQATSM----VEQGFWESVPEADPAR-AGPTSLGDIKGAADEILLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGV-E-----DPGTIFQ MOUSE5_PE2225 ISOFORMIN KDSAENNAHLDFMLALSLQNEGQATSM----VEQGFWESVPEADPAR-AGPTSLGDIKGAADEILLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGV-E-----DPGTIFQ MYOLUGS_5807_PE3 NOISO IEGGEDSSNLDFMLALSLQNEGQAPKL----AEQDFWRAVCEAEQSL-GGPKSLNDIKGAADETMLPCEFCEELYPEELLIDHQTSCNPSSALPSFNMGSTSLKEVEE-----DPDVIFQ OCHPRGS_607_1_PE4 NOISO KEVGEDTANLDFMLALSLQSEGQPSSL----SEQDFWRAICETDQPH-GTAHSQSDIKGAADETVLPCEFCEELYPEELLLDHQTSCNPSRALPSLNAGSSSPRGM-E-----DSDVIFQ ORNAN2_2_PE13 ENSOANG00000004805 PIYGDENSHLDYMLALSLQNESSLHSSSLNPEIENFWTALYRKDSSPSRGFSRAQDKEGADYKTMLPCEFCEELYPEEDLILHQTGCNPASVLASFRKRSSSPSPQRD------HAGHFR ORNAN2_2_PE14 ISOFORMIN PIYGDENSHLDYMLALSLQNESSLHSSSLNPEIENFWTALYRKDSSPSRGFSRAQV-AATDYKTMLPCEFCEELYPEEDLILHQTGCNPASVLASFRKRSSSPSPQRD------HAGHFR ORNAN2_2_PE15 ISOFORMIN PIYGDENSHLDYMLALSLQNESSLHSSSLNPEIENFWTALYRKDSSPSRGFSRAQ-----DYKTMLPCEFCEELYPEEDLILHQTGCNPASVLASFRKRSSSPSPQRD------HAGHFR PANTR12_118_PE6 NOISO KEGGEESANLDFMLALSLQNEGQASSV----AEQDFWRAVCEADQSH-GGPRSLSDIKGAADEIMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGV-E-----EPDVIFQ PIG14_41_PE16 NOISO KEGGEDSANLDFMLALSLQNEGQPPNM----AEQDLWRVVCEADQSH-EGPSALNDIRGAADGTMLPCEFCEELYPEELLIDHQTSCNPSCALPPLGVGSTSPKGM-E-----DPDVIFQ PONPY12_119_PE4 NOISO KEGGEDSANLDFMLALSLQNEGQASSV----AEQDFWRAVCEADQSH-GGPSSLSDIKGAADEIMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGV-E-----EPDVIFQ PROCAGS_3263_PE1 NOISO KEGGEDSANLDFMLALSLQNEGQVPHM----AEQDFWRAICEADQSR-GGPSALSDIKGATGETMLPCEFCEELYPEELLIDHQTSCNPSCALPPLTMGSSPPKVV-E-----DPDVIFQ PTEVAGS_3824_PE4 NOISO KEGGEDSANLDFMLALSLQNEGQAPSM----AERDFWRATYEADQSH-EGHRALNDIKGAADETMLPCEFCEELYPEELLIDHQTTCNSSCALPSFNMGSTSPKGV-E-----DSDVIFQ RABIT21_9_PE5 NOISO KEGGEDSANLDFMLALSLQNEGQSSSL----AEQDFWRAICEADQPH-GGPASLNDIKGAADETVLPCEFCEELYPEELLIDHQTSCNPSRAFPSLSTDSSSPRGM-Q-----DSDVIFQ RAT12_PE720 NOISO KDSAENSAHLDFMLALSLQNEGQASSM----VEQGFWESVPEADPAR-AGPTSLGDIKGAADETLLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGV-E-----DPGAIFQ SORAR140962_PE1 NOISO -VGG--DSATDYMLAL--LQSGQLPSV----AEQGFWRAVCEVGQSR-AGPSAPGSDAGADVETMLPCEFCEELYPEELFIDHQTSCNPSCSLPPLTVGSPSPRGV-E-----DPDVIFQ SPETRGS_2491_PE1 NOISO KEGGEDSANLDFMLALSLQNEGQASTV----AEQDFWRAVCEADQSH-GGPSSLSDMKGAADETMLPCEFCEELYPEDLLIDHQTSCNPSRALPSLNTGSSSSRGV-E-----DPDVIFQ TARSY42503_PE1 NOISO KKGGEDSANLDFMLALSLQNEGQASSM----AEQDFWKAVCEADQSH-GGPSSLRDIKGAADETMLPCEFEEFVAQE---TEHLTSCNPSRALTSLNTGSSFPRGV-E-----EPDVIFQ TUPGBGS_5528_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXX-XXXXXXXXXXXTADETMLPCEFCEELYPEELLIDHQTSCNPSHALPSLHTGSSSPKGV-E-----DPDVILQ TURTRGS_415_PE5 NOISO KEGGEDSANLDFMLALSLQNEGQAPNL----AEQDFWRVICEADQSH-EGPGALNDIRGAADETMLPCEFCEELYPEELLIDHQTSCNPSCALPPISVGNASPKGV-E-----DPDVIFQ MATCH * ** . . : . CONSENSUS ???GE????LD?MLALSLQ?E??????????????FW???????????????????????????MLPCEFCEELYPEE?LI?HQT?CNP??AL??????S??????????????????FQ

AILMEGL193246_1_PE3 NOISO KFLQQ---AA-SNQLDSLMGLNDSPPVED-GIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VTEGIPRQDFQPPETSPELPKRRVRHQGDLSSGYMDDIKQETAKGPTYP BOVIN17_66_PE12 ENSBTAG00000008761 KLMRE---SA-GGQFESLMGFSSSAPVED-SVVIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VSEGIPSQDLQPRETSPELPKRRVRHQGDLSSGYMNDLKQEMAKGPTYP BOVIN17_66_PE13 ISOFORMIN KLMRE---SA-GGQFESLMGFSSSAPVED-SVVIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VSEGIPSQDLQPRETSPELPKRRVRHQGDLSSGYMNDLKQEMAKGPTYP CALJA9_108_PE25 NOISO NFLQQ---AA-SNQLDSLMGLSNSRPVEE-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPTTATNH-----VTEGIPRLDSQPQETSPELPRRRVRHQGDLSSGYLDDIKQETANGPTSC CANFA26_14_PE4 ENSCAFG00000008830 KFLQQ---AA-NNQLDSLMGLSSSPPVKD-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VTEGIPRQDFQPPETSPDLPKRRVRHQGDLSSGYMDDIKQETAKGPTYP CANFA26_14_PE5 ISOFORMIN KFLQQ---AA-NNQLDSLMGLSSSPPVKD-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VTEGIPRQDFQPPETSPDLPKRRVRHQGDLSSGYMDDIKQETAKGPTYP CAVPO115_4_PE9 NOISO SFLQR---AT-SNQWDSLMGLSDSPPVED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATASHH-----VLDGIPRQDSQPPETSAELPRRRVKHQGDLSSGYMDDTKQEAAKGPTYS CHICK15_PE212 ENSGALG00000004802 -----------YNSCRSDYSSRYQAVQEEGNIIIPCEFCGKGLEEEIVFHHQ-DQCDLRPATANPADNLPSQQPPSPR-DNRERRESPDLARRRIRHQGDVSPGCIEDLRQQRLNCPAR- CHOHOGS_3501_PE1 NOISO KVLQQ---TE-NNHLDSLIGLTNSPPMEDSSIIIPCEFCGVQLEEEVLFHHQ-DQCDQRSATANNR-----VIEGFPSQDSQPRETSPELPRRRVRHQGDLSSGYLDGIKQETAKGPTYH DASNOGS_3144_PE1 NOISO KFLQQ---AA-NNQLDSSMGLTNSPPMED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQCLTMANNH-----V-TGFPRQNAQPQDTSPVLPRRCVRHQGDMPSGYMDDIQLQTDKGPTYP DIPORGS_2952_PE1 NOISO NILQQ---AT-YDQLGFITGLNTLSPVEG-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATAHSH-----GTEGFRRQDPQRQEASPEQLRRRSRHQGDLSSGYVEDTKQGTAKGSAYP ECHTEGS_3767_PE1 NOISO KFLQQ---A---NELESLMGLTSSPPVEE-SIIIPCEFCGVQLEEEVLFHHQ-XXXDQRPATTTLV-----T---RSRQDSQ-PETSPELPRRRVRHQGDLPTSYMELIKQEEAKGPTYP FELCAGS_2104_PE1 NOISO KFLQQ---AA-SNQLDSLMGLSNSPPVED-SVIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VTEGIPRQDFQHPETSPELPKRRVRHQGDLSSGYMDDIKQEMAKGPTYP GORGO12_117_PE5 NOISO NFLQQ---AA-SNQLDSLMGLSNSHPVEE-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPA---NH-----VTEGIPRLDSQPQETSPELPRRRVRHQGDLSSGYLDDIKQETANGPTSC HORSE8_21_PE5 NOISO KYLQQ---AA-SNQLDSLMGLSSSPPVED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VTEGIPRQDFQPRETSPELPKRRVRHQGDLSSGYMDDIKQETANGPAYP HS12_PE2264 ENSG00000135148 NFLQQ---AA-SNQLDSLMGLSNSHPVEE-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATATNH-----VTEGIPRLDSQPQETSPELPRRRVRHQGDLSSGYLDDTKQETANGPTSC HS12_PE2265 ISOFORMIN NFLQQ---AA-SNQLDSLMGLSNSHPVEE-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATATNH-----VTEGIPRLDSQPQETSPELPRRRVRHQGDLSSGYLDDTKQETANGPTSC LAMPAGS_432_PE5 NOISO KLMQQ---AA-SNQFDSLMGLSSSPPVED-SVIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATTNSH-----VSEGIPRPDFQPQETSPELPKRRVRHQGDLSSGYMDDLKQKTAKGPTYP LOXAF84_7_PE20 NOISO KFLQQ---A---NQLESLMGLPNSPPVED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANHH-----VMEGFPRQDSRPRETSPELPRRRVRHQGDLSSGYMDDTKQETAKGPTYP MACEUGS_4452_PE1 NOISO RLLDLPATRAISSRFRSLLDLPAAPSGES-GIIIPCEFCGVQLEEEVLFHHQ-DQCDLRPGTATRR-----MAEPLPKQDSLQPVTSPELPRRRIRHQGDLSSCYMDDIRQETASKPMYP MACMU11_117_PE5 NOISO NFLQQ---AA-SKQLDSLMGLSSSRLVEE-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATATNH-----VTEGIPRLDSQPQENSPELPRRRVRHQGDLSSGYLDDIKQETANGPTSC MICMUGS_1957_PE1 NOISO NFLQQ---AA-SNQLDSLMGMNNSPSVED-TVIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----GTEGIPRQDSQPRETSPELPRRRVKHQGDLSSGYMDDIKQETANGPTHP MONDO3_509_PE7 ISOFORMIN RFLDLPASRAISSRFRSPLDLSAAPSGES-SIIIPCEFCGVQLEEDVLFHHQ-DQCDLRPGTGVPVQWLLPAYESLPKQGSSQPETSPELPRRRVRHQGDLSSCYMDDIRQEAASKPAYP MONDO3_509_PE8 ISOFORMIN RFLDLPASRAISSRFRSPLDLSAAPSGES-SIIIPCEFCGVQLEEDVLFHHQ-DQCDLRPGTGVPVQWLLPAYESLPKQGSSQPETSPELPRRRVRHQGDLSSCYMDDIRQEAASKPAYP MONDO3_509_PE9 ENSMODG00000002929 RFLDLPASRAISSRFRSPLDLSAAPSGES-SIIIPCEFCGVQLEEDVLFHHQ-DQCDLRPGTGVPVQWLLPAYESLPKQGSSQPETSPELPRRRVRHQGDLSSCYMDDIRQEAASKPAYP MOUSE5_PE2224 ENSMUSG00000042726 NFLQQ---AT-SNQFDTLMGLSSSAAVED-SIIIPCEFCGVQLEEEVLFYHQ-DQCDQRPATANHR-----AVEGIPAQDSQPENTSAELSRRRVKHQGDLSSGYMDDVKPESVKGPTYS MOUSE5_PE2225 ISOFORMIN NFLQQ---AT-SNQFDTLMGLSSSAAVED-SIIIPCEFCGVQLEEEVLFYHQ-DQCDQRPATANHR-----AVEGIPAQDSQPENTSAELSRRRVKHQGDLSSGYMDDVKPESVKGPTYS MYOLUGS_5807_PE3 NOISO RFLQQ---AT-SNQFNSLMGLSNAPSVEG-GIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VMEEIPRQDFQSRETSPELPKRRVRHQGDLSSGYMDDIKQETAKVPTYP OCHPRGS_607_1_PE4 NOISO NFLQQ---AT-SSQLGTLMGLNSSHSVED-SVIIPCEFCGVQLEEEVLFHHQ-XXXXXXXXXXXXX-----XXXEMPGRSSQPPDTSPELLRRRVRHQGDLSSSFVENIKQEAAKGPTYS ORNAN2_2_PE13 ENSOANG00000004805 SFLELPATRAPGSRYRSLLELPAGPSAEG-SIIIPCEFCGVQLEEEILFHHQKDQCDLRPATGTPAERRPPADPWLPKQDNLQKDMSPELTRRRLRHQGDLPACYLDDIKPEVANRSLYP ORNAN2_2_PE14 ISOFORMIN SFLELPATRAPGSRYRSLLELPAGPSAEG-SIIIPCEFCGVQLEEEILFHHQKDQCDLRPATGTPAERRPPADPWLPKQDNLQKDMSPELTRRRLRHQGDLPACYLDDIKPEVANRSLYP ORNAN2_2_PE15 ISOFORMIN SFLELPATRAPGSRYRSLLELPAGPSAEG-SIIIPCEFCGVQLEEEILFHHQKDQCDLRPATGTPAERRPPADPWLPKQDNLQKDMSPELTRRRLRHQGDLPACYLDDIKPEVANRSLYP PANTR12_118_PE6 NOISO NFLQQ---AA-SNQLDSLMGLSNSHPVEE-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATATNN-----VTEGIPRVDSQPQETSPELPRRRVRHQGDLSSGYLDDIKQETANGPTSC PIG14_41_PE16 NOISO EIMQQ---AA-RNQL-DSLGLRSSPPVED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VSEGIPRQDFQPRGTSPELPKRRVRHQGDLSSDYMDDIKQEMAKGPTYP PONPY12_119_PE4 NOISO NFLQQ---AA-SNQLDSLMGLSNSHPVEE-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATATNH-----VTEGIPRLDSQPQETSPELPRRRVRHQGDLSSGYLDDIKQETANGPTSC PROCAGS_3263_PE1 NOISO KFLQQ---A---SQLESLMGLPSSPPVED-SIIIPCEFCGVQLEEEVLFHHQ-EQCDQRPATANHH-----VTEGFPGQDSRPRETSPELPRRRVRHQGELSSGYMDDIKQETPKGPTYP PTEVAGS_3824_PE4 NOISO KFLQQ---AA-SNQLDSLMGLNTSPLVED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATVNNH-----ATEGIPRQDFHSQETSPELPKRRVRHQGDLSSGYMDDIKQETDKGPAYP RABIT21_9_PE5 NOISO NFLQQ---AT-SNQLGSLMVLNNSRPVEE-SVIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----VLEGIPRRDSQLPKTSPELPRRRVRHQGDLSSGYMDDIKQETAQGP--- RAT12_PE720 NOISO NFLQQ---AT-SNQLDTLMGLSSSAAVED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANHR-----AMEGIPTQDSQPEDRSPELSRRRVKHQGDLSSGYMDDVKQESVKGSTYS SORAR140962_PE1 NOISO KLLQE---AA-SNQLDSLMGLKSPGPAED-SVIIPCEFCGVQLEEEVLFHHQ-DQCDQRPVTANHH-----VMEAIPRQESRPPATSPELPKRRLRHQGDLSFGYVDNTKQ--AKGPAHP SPETRGS_2491_PE1 NOISO NFLQQ---AT-SNQLDSLMGLSNSPPVED-SVIIPCEFCGVQLEEEVLFHHQ-DQCDQRPAMANNH-----VIEGIPKQPSQLQETSPELPRRRVRHQGELSSGYMDDIKQEIAKGPIYP TARSY42503_PE1 NOISO NFLQQ---AT-SNQLDSLMGLSSSPSVDD-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQHPATANNH-----VTEGIPRQDSQPRETSPELPRRRVRHQGDLSSGYMEEIKQETANGPTY- TUPGBGS_5528_PE3 NOISO NFLQQ---AA-SNQFKSLMGLSNSAPVED-SIIIPCEFCGVQLEEEVLFHHQ-------------------------------------------------------------------- TURTRGS_415_PE5 NOISO MXXXX---XXXXXQLDSLMGLSSSPSVED-SIIIPCEFCGVQLEEEVLFHHQ-DQCDQRPATANNH-----ISEGIPSQDLQPRQTSPELPKRRVRHQGDLSSGYMDDIKQEMAKGPTYP MATCH . ::******* ***:::*:** CONSENSUS ??L?????????????SL??L??????E??S?IIPCEFCGVQLEEEVLFHHQ?DQCD?RP?T??????????????P??D?????TSPEL??RRVRHQGDLSS?Y?DD?KQE?A??P???

AILMEGL193246_1_PE3 NOISO LPPSRPINNMTATCDRLSTSTSGPRP-GCQP--SPPRILKLNNLDSQD-GRVRNRN-SHNSAMATGHVPVIHPVRNLYPENLVPTFPRGPSGRHGVSGRSEGGRNSRVTSTTANYRNRTA BOVIN17_66_PE12 ENSBTAG00000008761 LPSSRPPNNTTAPPNRLSTSTSGPRP-GCQP--SPPRALKLNNLDSQG-VRGRSRN-SHNGALAPGHVPAAYPARSLYPENLVPSFPRGPSGRYGASSRSEGGRNPRVTPTAASYRSRTA BOVIN17_66_PE13 ISOFORMIN LPSSRPPNNTTAPPNRLSTSTSGPRP-GCQP--SPPRALKLNNLDSQG-VRGRSRN-SHNGALAPGHVPAAYPARSLYPENLVPSFPRGPSGRYGASSRSEGGRNPRVTPTAASYRSRTA CALJA9_108_PE25 NOISO LPPSRPINNMTATYNRLSRSTSGPRP-GCQP--SPPRVLKLNNSDSQD-IRGRNR-NSQNGAIAPGHVSVICPPPNLYPEN-VPSFPRAPAGRYGASGRSEGGRNSRVTPVAANYRSRTT CANFA26_14_PE4 ENSCAFG00000008830 LPPSRPINNMTATYNRLSTSTSGPRP-GCQP--SPPRILKLNNLDSQD-SRGRNRN-SHNAAMVTGHVPVIHPGRNLYPENLVPSFPRAPSGRYGVSGRNEGGRNSRVTSTTANYRNRTA CANFA26_14_PE5 ISOFORMIN LPPSRPINNMTATYNRLSTSTSGPRP-GCQP--SPPRILKLNNLDSQD-SRGRNRN-SHNAAMVTGHVPVIHPGRNLYPENLVPSFPRAPSGRYGVSGRNEGGRNSRVTSTTANYRNRTA CAVPO115_4_PE9 NOISO LPPSRAV-TMTAGCNRLSKSPSASRP-SCQP--SPSRVVKLSTSDGQD-MRARTRG-SPGGPPAAGPVPAMHPVRSLCAEGLAPSLPRGPAGRPAASS-----RSFRVTPAAPSYRSRSA CHICK15_PE212 ENSGALG00000004802 --GNRALSNAATARNAPLTSSGTVKTSDALNSRGKPRKVA-----G---NEGRLKN-RGAGEPASGATPCVRPTQNLHSETFTSSLSRTPVQ---TSIRSGRGRNPGTSDVPVGFRSRKV CHOHOGS_3501_PE1 NOISO LSPNRPITNMTATYNRLSKSTSGPRP-GCQP--SPSRVLKLNNSDSQD-IRGRNQN-SRNGTMATGHISVTHPVRNTYPENLVPSFPRGPAGRYGASGRSEGGRNSRVTPTAASYRNRTA DASNOGS_3144_PE1 NOISO LSSNRPINNIMTTQQQVGVEEEEEEE---------------------------------------------------------------------------------------------- DIPORGS_2952_PE1 NOISO LPPSRPMNNMTATCNRLLKSTPGPRS-GYQP--SPPRVLKLNNADGQE-LRGRSGG-GQNSSMATDHPSVIHSIRNLYPENLVPSLPRGPAGGYGASSRSEGSRSSRAAPAAANYRSRGA ECHTEGS_3767_PE1 NOISO LPPNRPMNSMTTPCNRMSRAVSGPRP-GGQP--SPPRVLKLNNSDSQD-IPGQNCN-SHNGALGPGHISAVHPVRNLYPEALV-SFPRGPGGRYGASGRSEGGRNSRVNPPAASYRNRTT FELCAGS_2104_PE1 NOISO LPPSRPINNMTATCNRLSTSTSSPRP-GCQP--SPPRILKLNNLDSQD-SRGRNRN-SHNSAMATGHAPVIHPVRNLYPENLVPSFPRGPSGRYGASGRSEGGRNSRVTSTAANYRNRTA GORGO12_117_PE5 NOISO LPPSRPINNMTATYNQLSRSTSGPRP-GCQP--SPPRVLKLSNSDSQD-IQGRNR-NSQNGAIAPGHVSVIRPPQNLYPENIVPSFSPGPAGRYGASGRSEGGRNSRVTPAAANYRSRTA HORSE8_21_PE5 NOISO LPPSRPINNMTAVCNRLSTSASGSRP-GCQP--SPPRVLKLNNLDSQD-IRGRNRN-SQNGAMATGHIPVMRSVRNLYPETLVPPFPRGPSGRYGASGRSEGGRNSRVTPATASCRSRTA HS12_PE2264 ENSG00000135148 LPPSRPINNMTATYNQLSRSTSGPRP-GCQP--SSPCVPKLSNSDSQD-IQGRNR-DSQNGAIAPGHVSVIRPPQNLYPENIVPSFSPGPSGRYGASGRSEGGRNSRVTPAAANYRSRTA HS12_PE2265 ISOFORMIN LPPSRPINNMTATYNQLSRSTSGPRP-GCQP--SSPCVPKLSNSDSQD-IQGRNR-DSQNGAIAPGHVSVIRPPQNLYPENIVPSFSPGPSGRYGASGRSEGGRNSRVTPAAANYRSRTA LAMPAGS_432_PE5 NOISO LPPSRPTSNMTATSNCLSTSTSGTRT-ACQP--SPPRAPKLNNSDSQG-TRGCSRS-SRNGALAPGHVPAIHPVRSLYPENLVPSFPRGPSGRYGASGRSEGGRNPRGTPTTTNFRNRTA LOXAF84_7_PE20 NOISO GPPNRPINNMMATYNRLSKSMSGPRP-GCQP--SPPRVLKLNNSDSQD-IRGQNGN-GHNGAVAPGHISVIHPVRNLYPENLVPSFPRGPAGRYGASGRSEGGRNSRVTAPAASYRNRTA MACEUGS_4452_PE1 NOISO LPPSRSTSSIGLARNRLPKALLDPRP-GVLP--SPPRVLKASNLDSLE-TRGQSRR---NHNPATGPNPTGRPTRSLYPENYVPSFPRVPPVRHGLSVRNEIGRNSRITPTAANFRNRTT MACMU11_117_PE5 NOISO LPPSRPFNNMTATYNQLSRSTSGPRP-GCQP--SPPRVLKLNNSDSQD-IQGRNQ-NSQNGAIAPGHISVIRPPQSLYPENIVPSFPHGPAGRYGASGRSEGGRNSRVTPAAANYRSRTA MICMUGS_1957_PE1 NOISO LPPSRPINNMTATSNRLSKSTSGPRP-GCQA--SPPCVLKLNNPDSQD-IHGLNRN-SQNGAVATGHVPVIHPVRNLYSENLVPTFPSGSAGRYGAGGRSVGGRNTRVTPVAGSYRSRTA MONDO3_509_PE7 ISOFORMIN LPPSRPVSSLGLARNRLPKAATDSRP-AVLP--SPPRALKANNLESLDLIRGQSRS---GHSPAAGPISVVRPTRSFYPESYVPSFPRVPPVRHGLSVRNEGGRNPRMTSTAANFRNGTS MONDO3_509_PE8 ISOFORMIN LPPSRPVSSLGLARNRLPKAATDSRP-AVLP--SPPRALKANNLESLDLIRGQSRS---GHSPAAGPISVVRPTRSFYPESYVPSFPRVPPVRHGLSVRNEGGRNPRMTSTAANFRNGTS MONDO3_509_PE9 ENSMODG00000002929 LPPSRPVSSLGLARNRLPKAATDSRP-AVLP--SPPRALKANNLESLDLIRGQSRS---GHSPAAGPISVVRPTRSFYPESYVPSFPRVPPVRHGLSVRNEGGRNPRMTSTAANFRNGTS MOUSE5_PE2224 ENSMUSG00000042726 MSPNRTMNNV-ASCNRLLNLPSGPRS-DCQR--SPPGVLKLNNSDSQD-IRGQMRG-SQNGPIASGHAPVIHSIQNLYPENFAPSFPHGSPGRYGAGGRSEGGRSSRVSPAAAGYHSRAA MOUSE5_PE2225 ISOFORMIN MSPNRTMNNV-ASCNRLLNLPSGPRS-DCQR--SPPGVLKLNNSDSQD-IRGQMRG-SQNGPIASGHAPVIHSIQNLYPENFAPSFPHGSPG----SGRSEGGRSSRVSPAAAGYHSRAA MYOLUGS_5807_PE3 NOISO LPPSRPINNMMATCNRVSTSTSSPKS-TS-----QPSVMKLNNLDSQD-IRGRNRN-SHNGPMAAGHVPVIRSVRNLYPENLAPSFSRGPSGRHGPSGRSEGGRNSRVTATTASFRNRTA OCHPRGS_607_1_PE4 NOISO LAPSRPLNNTTTTYSRLSKLTSGRRP-GCQA--SPSHLPRLGSG-SQD-TGAQNQN-GRNGTVAAAHVPVIQPIGSLCPETLLTSLSRGPAGRLGTGAKSEGGRSSRATPAAANCRNRTA ORNAN2_2_PE13 ENSOANG00000004805 LPPSRPVSNLAVTRNYLPKPPATGAS-G-PS--TPPQTLKPNNLEAQD-LRGRSRS---ALSPGLGLNSGVRTPRGFYPENLTSGFPRPPPVRHGPSVKNDGGRTPRLTPATASFRSRTT ORNAN2_2_PE14 ISOFORMIN LPPSRPVSNLAVTRNYLPKPPATGAS-G-PS--TPPQTLKPNNLEAQD-LRGRSRS---ALSPGLGLNSGVRTPRGFYPENLTSGFPRPPPVRHGPSVKNDGGRTPRLTPATASFRSRTT ORNAN2_2_PE15 ISOFORMIN LPPSRPVSNLAVTRNYLPKPPATGAS-G-PS--TPPQTLKPNNLEAQD-LRGRSRS---ALSPGLGLNSGVRTPRGFYPENLTSGFPRPPPVRHGPSVKNDGGRTPRLTPATASFRSRTT PANTR12_118_PE6 NOISO LPPSRPINNMTATYNQLSRSTSGPRP-GCQP--SPPRVLKLSNSDSQD-IQGRNR-NSQNGAIAPGHVSVIRPPQNLYPENIVPSFSPGPAGRYGASGRSEGGRNSRVTPAAANYRSRTA PIG14_41_PE16 NOISO LPLSRPINNMTATSNRLSVSTSGPRP-GCQP--SPPRTLKLNNLDNQG-IRGRNRN-SHNGALASEQIPAVHPARSLYPENLVSAFPRGPSGRYGASGRSEGGRNSRVTPTTTSYCSRTV PONPY12_119_PE4 NOISO LPPSRPINNMTATYNQLSRSTSGPRP-GCQP--SPPRVLKLSNSDSQD-IRGQNRPNSQNGAIAPGHVSVIRPPQNLYAENIVPSFSLGPAGRYGASGRSEGGRNSRVTPAAANYHSRTA PROCAGS_3263_PE1 NOISO LPHNRPIDSMTPTYNRLSK--SGPRP-GCQP--SPPRVLKLNNADSQD-TQGQHRN-SHNGAGAPGHISVIHPVRSLYPENLVPSFPYGPAGRYGAS-RNESGRNSRVTSSAANYRNRVA PTEVAGS_3824_PE4 NOISO LPPSRPINNVTAAYDRLSASTSGPRP-GCPP--SPPRVLKLNNLDNQD-SRGQSQN-SHNGALASGH-----PVRNLYPENLVPSFPRGPSGRYGASGRSEGGRNSRVTPTTAGYRSRTV RABIT21_9_PE5 NOISO --SGRPLNNTTATCNRLPKSTSSRRP-GCQA--SPSHVLRLNSSAIQD-AGGQNRS-SQNGAMAAGHLPVMQPVRSPYPETLVSSSPRGPAGRCAASGRSEGGRNSRVTPATTSYRSRAV RAT12_PE720 NOISO LSPNRTMNNV-STCNRLLN-SSGPRS-DCQR--SPPGVLKLNNSGSQD-IRGRIRG-SQNGPIASAHAPVIHSIRNLYPENLAPSFPHGSPGRFGASGRSEGSRSSRVTPTAASYHSRAA SORAR140962_PE1 NOISO LAPGSPLGSLVPPCGQLAAAAPSSRP-ACQL--SPPRVLKLSNLAGQD-PRGRSRS-SLSGAPAPGHSPALHSARTLYPENLAPSFPRGPAGRFGASGR-----SARVAAAPASYR-RAA SPETRGS_2491_PE1 NOISO LPPSRPINNITTTCNRLSKSTSGSTT-GCQP--NPPRVLKLNNSDSQD-IRGRNRSS-QNGAMDTEH-----SVRNLHPEYLVSSFPVGPAGRYGASGRSEGGRSSRVTPAATNYRNRTA TARSY42503_PE1 NOISO -PPSRPINNMTAAYDRLSKLTSGPRT-GFQP--SPPHVPKLNNSDSQG-IQERNQN-SQNGAMATGHVPVIQPVRNLYPENLVPSFPCGPAGRYRT------------------------ TUPGBGS_5528_PE3 NOISO ------------------------------------------------------------------------------------------------------------------------ TURTRGS_415_PE5 NOISO LPASRPTNNMTATSNRLTTSTSGPRP-GCQP--SPPRALKLNNLDSQG-IQGHNRN-SHNGALAPGHVPVVHSARSLYPENLVPSFPRGPSGRCGASGRSEGGRNPRVTPTTASYRSRTA MATCH CONSENSUS L???RP????????N?L???????R????????SPP???K??N???Q????G?????????????G???????????YPE?????F???P??R?G?S?R??GGR??R????????R?R??

AILMEGL193246_1_PE3 NOISO KAKPPKQQGAGDAEEEEEE- BOVIN17_66_PE12 ENSBTAG00000008761 KAKTPKQQGAGDAEEEEE-- BOVIN17_66_PE13 ISOFORMIN KAKTPKQQGAGDAEEEEE-- CALJA9_108_PE25 NOISO KAKPSKQQGAGDVEEEEEE- CANFA26_14_PE4 ENSCAFG00000008830 KAKPPKQQGAGDAEEEEEE- CANFA26_14_PE5 ISOFORMIN KAKPPKQQGAGDAEEEEEEE CAVPO115_4_PE9 NOISO KAKPPKQDGAWARPSVHSS- CHICK15_PE212 ENSGALG00000004802 KAKPQSPESG-YPEEE---- CHOHOGS_3501_PE1 NOISO KAKASKQQGAGAVEKEEEEE DASNOGS_3144_PE1 NOISO -------------------- DIPORGS_2952_PE1 NOISO KAKP-KPQGAGDAEEEEE-- ECHTEGS_3767_PE1 NOISO K------------------- FELCAGS_2104_PE1 NOISO KAKTPKQQGAGDAEEEEEEE GORGO12_117_PE5 NOISO KAKPSKQQGAGDAEEEEEE- HORSE8_21_PE5 NOISO KAKTPKQQGAGDAEEEEEE- HS12_PE2264 ENSG00000135148 KAKPSKQQGAGDAEEEEEE- HS12_PE2265 ISOFORMIN KAKPSKQQGAGDAEEEEEE- LAMPAGS_432_PE5 NOISO KAKAPKHQGAGDAEEGEEE- LOXAF84_7_PE20 NOISO KAKSPKQQGAGDVEEEEE-- MACEUGS_4452_PE1 NOISO KTKSPKP-AAGDAEEEEP-- MACMU11_117_PE5 NOISO KAKPSKQQGAGDAEEEEEE- MICMUGS_1957_PE1 NOISO KAKPPKQQGAGDAEEEEEEE MONDO3_509_PE7 ISOFORMIN KTKSPKP-AAGDAEEEEE-- MONDO3_509_PE8 ISOFORMIN KTKSPKP-AAGDAEEEEE-- MONDO3_509_PE9 ENSMODG00000002929 KTKSPKP-AAGDAEEEEE-- MOUSE5_PE2224 ENSMUSG00000042726 KAKPPKQQGAGDAEEEEE-- MOUSE5_PE2225 ISOFORMIN KAKPPKQQGAGDAEEEEE-- MYOLUGS_5807_PE3 NOISO KAKPPKQQGAGDAEEEEEE- OCHPRGS_607_1_PE4 NOISO KAKPPKQQGAGDAEEEEEE- ORNAN2_2_PE13 ENSOANG00000004805 KAKPQKP-GTRDSEREEE-- ORNAN2_2_PE14 ISOFORMIN KAKPQKP-GTRDSEREEE-- ORNAN2_2_PE15 ISOFORMIN KAKPQKP-GTRDSEREEE-- PANTR12_118_PE6 NOISO KAKPSKQQGAGDAEEEEEE- PIG14_41_PE16 NOISO KAKPPKQQGAGDAEEEEEEE PONPY12_119_PE4 NOISO KAKPSKQQGAGDAEEEEEE- PROCAGS_3263_PE1 NOISO KAKSPKQQGAGDVEEEERW- PTEVAGS_3824_PE4 NOISO KAKPPKQQGAGDAEEEEEEE RABIT21_9_PE5 NOISO KAKPAKQQGAGDAEEEEEE- RAT12_PE720 NOISO KAKPPKQQGAGDAEEEEEEE SORAR140962_PE1 NOISO KAKPPKQ-GAGAGEEE---- SPETRGS_2491_PE1 NOISO KAKPPKQQGAGDAEEEEEEE TARSY42503_PE1 NOISO -------------------- TUPGBGS_5528_PE3 NOISO -------------------- TURTRGS_415_PE5 NOISO KAKPSKQQGAGDAEEEEEEE MATCH CONSENSUS KAK??K???A?D?E?EE???


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