Alignment of the gene Family HOG000154747 of HOGENOM

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Isoforms are ON
AILMEGL192963_1_1_PE4 NOISO ------------------------------------------------------------ AILMEGL193692_1_PE3 NOISO ------------------------------------------------------------ ANOCA247_1_PE5 NOISO ------------------------------------------------------------ ANOCA861_PE1 NOISO ------------------------------------------------------------ CALJA14_23_PE19 ISOFORMIN ------------------------------------------------------------ CALJA14_23_PE20 ENSCJAG00000019738 ------------------------------------------------------------ CALJA14_23_PE21 ISOFORMIN ------------------------------------------------------------ CALJA7_88_PE1 NOISO ------------------------------------------------------------ CANFA15_16_PE5 NOISO ------------------------------------------------------------ CANFA17_44_PE12 NOISO --------------------------PFLPSSPRAPRLSAAPRPPASRAGGPLL-PCSFP CAVPO189_1_PE3 ENSCPOG00000011762 ------------------------------------------------------------ CHICK8_PE524 NOISO ------------------------------------------------------------ CHICKZ_PE728 NOISO ------------------------------------------------------------ CIOSAREFTIG_97_PE39 NOISO ------------------------------------------------------------ DANRE5_1_PE8 NOISO ------------------------------------------------------------ DANRE8_22_PE1 NOISO ------------------------------------------------------------ FELCAGS_1375_PE2 NOISO RGCLRAG-RRGG-GVGGGRLMFHPTLH-LPSSP-EPRPEA-PRP--RLAGGHRCLTLSLR GASACGROUPVIII_16_PE1 NOISO ------------------------------------------------------------ GORGO2A_91_PE1 NOISO ------------------------------------------------------------ HORSE15_20_PE17 NOISO ------------------------------------------------------------ HORSE2_12_PE1 NOISO ------------------------------------------------------------ HS2_PE2202 ISOFORMIN ------------------------------------------------------------ HS2_PE2203 ENSG00000186854 ------------------------------------------------------------ HS2_PE2204 ISOFORMIN ------------------------------------------------------------ LOXAF17_51_PE4 NOISO ------------------------------------------------------------ MACEUGS_7714_PE1 NOISO ------------------------------------------------------------ MACMU13_88_PE7 NOISO ------------------------------------------------------------ MACMU1_53_PE12 NOISO ------------------------------------------------------------ MICMUGS_1292_PE2 NOISO RGCLGAGG----------GSGPGPTWPQPPGLSR-PSP-GARRPRIAGPSGQRCSTPSLR MONDO1_736_PE19 NOISO ------------------------------------------------------------ MONDO2_7_PE11 NOISO ------------------------------------------------------------ MOUSE4_PE1819 NOISO ------------------------------------------------------------ NEMVE_5827_PE59 NOISO ------------------------------------------------------------ OCHPRGS_3496_PE5 NOISO HSCLALGLARGEAGLGG----PRPTWP-PPNSP-GPRPEA-LRLRLTPASGSSFLARSRR ORNANCONTIG68680_PE1 ENSOANG00000006858 ------------------------------------------------------------ ORNANCONTIG68680_PE2 ISOFORMIN ------------------------------------------------------------ PANTR2A_91_PE5 NOISO RCRLGAGLTCGG-GVGGGRSGPGPTWPLLPGSP-QPRPEAAPRPRLARAGGHLCPTPSLR POEGU8_21_PE1 NOISO ------------------------------------------------------------ POEGUZ_4_PE1 ENSTGUG00000000145 ------------------------------------------------------------ PONPY2A_26_PE13 NOISO RGRLGAGMTCGG-GVGGGRLGFTLLARILXX-X-XXXXXXAPRPRLARAGGHRCPTPSLR PTEVAGS_3597_PE1 NOISO RGLLYTGLTGSG---GSGGVRPGPTWPQPGGSG--PLPE-VPRPRPAKTGVPCRLTPCLR RABIT2_103_PE7 NOISO ------------------------------------------------------------ RAT5_PE1104 NOISO ------------------------------------------------------------ SORARGS_5477_PE4 NOISO ------------------------------------------------------------ SPETRGS_1659_PE2 NOISO --------------------------------------------------GYRYVTCSFR TURTRGS_2563_PE3 NOISO RGCLCSGQTGGG---GVGRSGFSLTWPPPPGLG-EPRPEA-QRPRLAEPGGHCWVPPSLC XENTR202_2_PE20 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192963_1_1_PE4 NOISO ----------MSPWSWFLLPTLCLLPTSAAPQRGALASANCELKPQQSELNSFLWTIKRD AILMEGL193692_1_PE3 NOISO ------------------------------------------LPLQQRELNSFLWTIRRD ANOCA247_1_PE5 NOISO ----------------------------------------------QKDLNSFLWTIRRN ANOCA861_PE1 NOISO ---------------------------------------------QQSELNSFLWTIKRD CALJA14_23_PE19 ISOFORMIN ----------MSPWSWFLLQTLCLLSTGAAPRRGAPGAANCDLKPQQSELNSFLWTIKRD CALJA14_23_PE20 ENSCJAG00000019738 ----------MSPWSWFLLQTLCLLSTGAAPRRGAPGAANCDLKPQQSELNSFLWTIKRD CALJA14_23_PE21 ISOFORMIN ----------MSPWSWFLLQTLCLLSTGA--------AANCDLKPQQSELNSFLWTIKRD CALJA7_88_PE1 NOISO ----------------------------------------------QRDLNSFLWTIRRD CANFA15_16_PE5 NOISO ------------------------------------------LPLQQRELNSFLWTIRRD CANFA17_44_PE12 NOISO RAGPRSRGGKMSPWSWFLLPTLCSCPQ---------SSAECELQPQQSELNSFLWTIKRD CAVPO189_1_PE3 ENSCPOG00000011762 -------------------------------------------------------TIRRH CHICK8_PE524 NOISO ---------------------------------------------QQGELNSFLWTIRRD CHICKZ_PE728 NOISO ---------KMSPIHIYSLGLVCLLPTNA--KNNAPGTAECWRKPWQSELNSFLWTIKRD CIOSAREFTIG_97_PE39 NOISO ------------------------------------------------------------ DANRE5_1_PE8 NOISO -MTMTMMTMMMVSWSAFL--QICWILMVRANQFNPGEPSGCRTNTPQSDLNSFLWTIKRD DANRE8_22_PE1 NOISO ---------MNCQSGLRWLVTLCAFFQVGSARDTHESTRQCDKPVSQKDMNSFLWTVKRP FELCAGS_1375_PE2 NOISO VRGLRAAVGRMSPWGWFLLQTLCLLPTGAAPRRGAPASANCELKPQQSELNSFLWTIKRD GASACGROUPVIII_16_PE1 NOISO ---------------------------------------------QQSDMNSFLWRVNRA GORGO2A_91_PE1 NOISO ----------MSPWSWFLLQTLCLLPTGAASRRGAPGAANCELKPQQSKLNSFLWTIKRD HORSE15_20_PE17 NOISO ----------------------------------------------QSELNSFLWTIKRD HORSE2_12_PE1 NOISO ----------------------------------------------QRDLNSFLWTIRRD HS2_PE2202 ISOFORMIN ----------MSPWSWFLLQTLCLLPTGAASRRGAPGTANCELKPQQSELNSFLWTIKRD HS2_PE2203 ENSG00000186854 ----------MSPWSWFLLQTLCLLPTGAASRRGAPGTANCELKPQQSELNSFLWTIKRD HS2_PE2204 ISOFORMIN ----------MSPWSWFLLQTLCLLPTGAASRRGAPGTANCELKPQQSELNSFLWTIKRD LOXAF17_51_PE4 NOISO ---MHAAL-----VG----PLLAALLVTTRARPQPPDGGQCRPPGSQRDLNSFLWTIRRD MACEUGS_7714_PE1 NOISO ----------------------------------------------QSELNSFLWTIKRD MACMU13_88_PE7 NOISO ---------------------------------------------QQSELNSFLWTIKRD MACMU1_53_PE12 NOISO ------------------------------------------LLLQQRDLNSFLWTIRRD MICMUGS_1292_PE2 NOISO VPGFGCAVRTMRPWSWFLLPTLCLLPTGAAPA---PAAANCDLKPQQSELNSFLWTIKRD MONDO1_736_PE19 NOISO ---------------------------------------------QQSELNSFLWTIKRD MONDO2_7_PE11 NOISO ----------------------------------------------QGDLNSFLWTIHRD MOUSE4_PE1819 NOISO ---MHAAL-----AG----PLLAALLATARARPQPPDGGQCRPPGSQRDLNSFLWTIRRH NEMVE_5827_PE59 NOISO --------------------------------------------QPQKNFNSFLWLVKRT OCHPRGS_3496_PE5 NOISO RPARRAASGRMSPWSWFLLPTLCLLPTDAVPRREAPTSANCKLKPQQSHFNSFLWTIKRD ORNANCONTIG68680_PE1 ENSOANG00000006858 ---------------------------------------------HEVFLKSYLWISRAG ORNANCONTIG68680_PE2 ISOFORMIN ---------------------------------------------HEVFLKSYLW----G PANTR2A_91_PE5 NOISO VPGLGAALRRMSPWSWFLLQTLCLLPTGAASRRGAPGTANCELKPQQSELNSFLWTIKRD POEGU8_21_PE1 NOISO ---------------------------------------------QQGELNSFLWTIRRD POEGUZ_4_PE1 ENSTGUG00000000145 ---------------------------------------------QQNELNSFLWTIKRD PONPY2A_26_PE13 NOISO VPGLGATVRRMSPWSWFLLQTLCLLPTGAASRRGAPGAANCELKPQQSELNSFLWTIKRD PTEVAGS_3597_PE1 NOISO ANGVGDGVRRMSPWRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQSELNSFLWTIKRD RABIT2_103_PE7 NOISO ----------MNPRSWFLLQILCLLPTGAVPRREAPASANCELKPQQSDLNSFLWTIKRD RAT5_PE1104 NOISO ---MHAAL-----AG----PLLAALLATARARPQPPDGGQCRPPGSQRDLNSFLWTIRRH SORARGS_5477_PE4 NOISO ----------------------------------------------QSELNSFLWTIKRD SPETRGS_1659_PE2 NOISO VPSSEAAVRRMF-----RLPTLFCL-----SRLRAPTSSNWEFKLQQIQLNYFLWTIKD- TURTRGS_2563_PE3 NOISO APGLGATERRMSPWSWFLMPTLCLLPASAAPPHGAPASANCKLKAQQNELNSFLWTIKRD XENTR202_2_PE20 NOISO --------MMVIIWNIFLPA--FLLVLAKASLRSSRDSANCKLNKKQSQLNSFLWTIKRD MATCH CONSENSUS ?????????????????????????????????????????????QQSELNSFLWTIKRD

AILMEGL192963_1_1_PE4 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFQQSSIVYFELDLTNPYTITALARCQMLP AILMEGL193692_1_PE3 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASARVYFELDLTDPYTISALASCQLLP ANOCA247_1_PE5 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQTSSSVYFELDLTDPYTISGLASCQLLP ANOCA861_PE1 NOISO ----PPSYFFGTIHVPYTRVWDHIPENSKKAFQQSHIVYFELDLTDPYTISALTSCQLLP CALJA14_23_PE19 ISOFORMIN ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP CALJA14_23_PE20 ENSCJAG00000019738 ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP CALJA14_23_PE21 ISOFORMIN ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP CALJA7_88_PE1 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASARVYFELDLTDPYTISALASCQLLP CANFA15_16_PE5 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASARVYFELDLTDPYTISALASCQLLP CANFA17_44_PE12 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFQQSSIVYFELDLTDPYTISALTSCQMLP CAVPO189_1_PE3 ENSCPOG00000011762 ----PPAYLFGTIHVPYTRVWDFIPDNSKATFQASARVYFELDLTDPYTVSALASCQLLP CHICK8_PE524 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFHASSSVYFELDLTDPYTISGLASCQMLP CHICKZ_PE728 NOISO ----PPSYFFGTIHVPYTRVWDFIPENSKKAFQQSHVVYFELDLTDPYTISALTSCQLLP CIOSAREFTIG_97_PE39 NOISO ------------------------------------------------------------ DANRE5_1_PE8 NOISO ----PPSYLYGTIHVPYTRVWDFIPQNSKQAFQESSVVYFELELTDPSTISALSRCQLLP DANRE8_22_PE1 NOISO -RPFPPSYLFGTIHVPYTRVWDYIPESSKRAFQTSNSVFFELDLTDPLTISKLTSCQLLP FELCAGS_1375_PE2 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFQQSSIVYFELDLTDPYTISALTSCQMLP GASACGROUPVIII_16_PE1 NOISO -PPHPPSYLFGTIHVPYTRVWDFIADRSKQAFHSSRNVFFELDLTDPLTISKLTSCQLLP GORGO2A_91_PE1 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP HORSE15_20_PE17 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFQQSSIVYFELDLTDPYTISALTSCQMLP HORSE2_12_PE1 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASARVYFELDLTDPYTISALASCQLLP HS2_PE2202 ISOFORMIN ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP HS2_PE2203 ENSG00000186854 ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP HS2_PE2204 ISOFORMIN ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP LOXAF17_51_PE4 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASARVYFELDLTDPYTISALASCQLLP MACEUGS_7714_PE1 NOISO ----PPSYFFGTIHVPYTRVWDFIPENSKAAFQQSSIVYFELDLTDPYTISALTSCQLLP MACMU13_88_PE7 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSTVYFELDLTDPYTISALTSCQMLP MACMU1_53_PE12 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASAHVYFELDLTDPYTISALASCQLLP MICMUGS_1292_PE2 NOISO ----PPSYFFGTIHVLYTRVWDFIPDSSREAFQQSSAVYLELDPTDPCAVPALTGCQMLE MONDO1_736_PE19 NOISO ----PPSYFFGTIHVPYTRVWDFIPENSKAAFQQSSIVYFELDLTDPYTISALTSCQMLP MONDO2_7_PE11 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFEASARVYFELDLTDPYTISALASCQLLP MOUSE4_PE1819 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASTHVYFELDLTDPYTISALASCQLLP NEMVE_5827_PE59 NOISO ----PPAYFYGTIHVPYTRVWDFIPMNSKQAFTASQHVYFELDLTDEKTMRALMKCQMLP OCHPRGS_3496_PE5 NOISO ----PPSYFFGTIHVPYTRVWDFIPDHSKEAFQRSSAVYLELDLTDPDTLSALASCQMLP ORNANCONTIG68680_PE1 ENSOANG00000006858 GSRSPPCYQCRTKHVPASFLRGIIPEDAKAALATSSRVYFELDLTGPFTISALASCQLLP ORNANCONTIG68680_PE2 ISOFORMIN GSRSPPCYQCRTKHVPASFLRGIIPEDAKAALATSSRVYFELDLTGPFTISALASCQLLP PANTR2A_91_PE5 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLP POEGU8_21_PE1 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFHASSSVYFELDLTDPYTISGLASCQMLP POEGUZ_4_PE1 ENSTGUG00000000145 ----PPSYFFGTIHVPYTRVWDFIPENSKKAFQQSHIVYFELDLT-PYTISALTSCQLLH PONPY2A_26_PE13 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSNTVYFELDLTDPYTISALTSCQMLP PTEVAGS_3597_PE1 NOISO ----PLSYFFSTIHVPYTRVWDFIPNNSKEAFQHNSIVYFELDLTDPYTISTLTSCQMLP RABIT2_103_PE7 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFQHSSIVYFELDLTDPYTISALTSCQMLP RAT5_PE1104 NOISO ----PPAYLFGTIHVPYTRVWDFIPDNSKAAFQASTRVYFELDLTDPYTISALASCQLLP SORARGS_5477_PE4 NOISO ----PPSYFFGTIHVPYTRVWDFIPDNSKEAFQRSSIVYFELDLTDPYTISALTSCQMLP SPETRGS_1659_PE2 NOISO -----PSYSFGIIHVP-TLVWDFITNNSKKAFQQSNIMYFELDLMDSYTISVLSSCQMMP TURTRGS_2563_PE3 NOISO ----PLSYFFGTIHVPYTRVWDFIPDTSKEAFQQSSIAYFELDLTDPYTISALTSCQLLP XENTR202_2_PE20 NOISO ----PPSYFFGTIHVPYTRVWDFIPENSKTAFQQSNIVYFELDLTDPYTISALTSCQMLP MATCH CONSENSUS ????PPSYFFGTIHVPYTRVWDFIPDNSK?AFQ?SS?VYFELDLTDPYTISALTSCQMLP

AILMEGL192963_1_1_PE4 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK AILMEGL193692_1_PE3 NOISO HGENLQDVLPRELYWRLKRHLDYVKLMMPSWMTPA---QRGKGLYADYLFNAIAGNWERK ANOCA247_1_PE5 NOISO HGENLQNVLPRDLYHRLKRHLEYVKLMLPHWMTPD---QRGKGLYADYLFNAIAGNWERK ANOCA861_PE1 NOISO QGENLQDVLPRDIYRRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK CALJA14_23_PE19 ISOFORMIN QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK CALJA14_23_PE20 ENSCJAG00000019738 QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK CALJA14_23_PE21 ISOFORMIN QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK CALJA7_88_PE1 NOISO HGENLQDVLPHELYWRLKRHLDYVKLMMPSWMTPA---QRGKGLYADYLFNAIAGNWERK CANFA15_16_PE5 NOISO HGENLQDVLPRDLYWRLKRHLDYVKLMMPSWMTPA---QRGKGLYADYLFNAIAGNWERK CANFA17_44_PE12 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK CAVPO189_1_PE3 ENSCPOG00000011762 PGENLQDVLPQELYWRLKRHLDYVKLMMPSWMTPA---QRGKGLYADYLFNAIAGNWERK CHICK8_PE524 NOISO HGENLQDVLPRELYRRLKRHLDYIKLMLPHWMTPD---QRGKGLYADYLFNAIAGNWERK CHICKZ_PE728 NOISO QGENLQDVLPRDIYRRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK CIOSAREFTIG_97_PE39 NOISO ---------------------------MTSWVTSK---QVEQGLTARLMYNELVGGWERK DANRE5_1_PE8 NOISO AGQNLQDVLPPELYLRLKTHLEYVRLMLPSWMTPD---QRGKGLYAEYLFNAIAGNWERK DANRE8_22_PE1 NOISO NGENLQTLLPRDLYRRLKRHLDYVKHMMPFWMTAD---QRGRGLYADYLFNAIAGNWERK FELCAGS_1375_PE2 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK GASACGROUPVIII_16_PE1 NOISO HGENLQTLLPRDLYRRLKRHLDYVKHRMPHWMTAD---QRGRGLYADYLFNAIAGNWERK GORGO2A_91_PE1 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPLWMTPD---QRGKGLYADYLFNAIAGNWERK HORSE15_20_PE17 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGQGLYADYLFNAIAGNWERK HORSE2_12_PE1 NOISO HGENLQDVLPRELYWRLKRHLDYVKLMMPSWMTPA---QRGKGLYADYLFNAIAGNWERK HS2_PE2202 ISOFORMIN QGENLQDVLPRDIYCRLKRHLEYVKLMMPLWMTPD---QRGKGLYADYLFNAIAGNWERK HS2_PE2203 ENSG00000186854 QGENLQDVLPRDIYCRLKRHLEYVKLMMPLWMTPD---QRGKGLYADYLFNAIAGNWERK HS2_PE2204 ISOFORMIN QGENLQDVLPRDIYCRLKRHLEYVKLMMPLWMTPD---QRGKGLYADYLFNAIAGNWERK LOXAF17_51_PE4 NOISO HGENLQDVLPRELYWRLKRHLDYVKLMMPSWMTPA---QRGKGLYADYLFNAIAGNWERK MACEUGS_7714_PE1 NOISO QGENLQDVLPQDIYCRLKRHLDYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK MACMU13_88_PE7 NOISO QGKNLQDVLPKDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK MACMU1_53_PE12 NOISO HGENLQDVLPRELYWRLKRHLDYVKLMMPSWMTPA---QRGRGLYADYLFNAIAGNWERK MICMUGS_1292_PE2 NOISO --ESLQDVLPSDIYCCLERHLEYVKLMMSPWLTPE---RRGKGLYADCLFNAITGNWEGE MONDO1_736_PE19 NOISO QGENLQDVLPQDIYCRLKRHLDYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK MONDO2_7_PE11 NOISO HGENLQDVLPRELYRRLKRHLDYVKLMMPTWMTPD---QRGKGLYADYLFNAIAGNWERK MOUSE4_PE1819 NOISO HGENLQDVLPRELYWRLKRHLDYVKLMIPSWMTPA---QRGKGLYADYLFNAIAGNWERK NEMVE_5827_PE59 NOISO SGTMLRQTLPRKMFKRLKSHLRYIKRMIPKWIKHRDQETSSAGPYANKLYEMLTKDWDKK OCHPRGS_3496_PE5 NOISO QGGHLQDVLPSHIYHRLKRHLEYVKLMLPSWMTPD---QRGQGLYADYLFNAIAGNWERK ORNANCONTIG68680_PE1 ENSOANG00000006858 PGENLQGLLPRELYHRLKRHLDYVRFMMPAWVTPD---QRGRGLYPDYLFNAIAGNWERK ORNANCONTIG68680_PE2 ISOFORMIN PGENLQGLLPRELYHRLKRHLDYVRFMMPAWVTPD---QRGRGLYPDYLFNAIAGNWERK PANTR2A_91_PE5 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPLWMTPD---QRGKGLYADYLFNAIAGNWERK POEGU8_21_PE1 NOISO HGENLQDVLPRELYRRLKRHLDYIKLMLPHWMTPD---QRGKGLYADYLFNAIAGNWERK POEGUZ_4_PE1 ENSTGUG00000000145 RGRTSKDVLPRDIYRRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWEQK PONPY2A_26_PE13 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPLWMTPD---QRGKGLYADYLFNAIAGNWERK PTEVAGS_3597_PE1 NOISO QGKNLQ---------------------MPLWITPD---QRGKSLYADYLYNAITGNWEHK RABIT2_103_PE7 NOISO QGENLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK RAT5_PE1104 NOISO HGENLQDVLPRELYWRLKRHLDYVKLMMPSWMTPA---QRGKGLYADYLFNAIAGNWERK SORARGS_5477_PE4 NOISO QGKNLQDVLPRDIYCRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK SPETRGS_1659_PE2 NOISO SK--NLDVLARDIYFCLKCHLEYVKLRMPLWMSD-----QGKGLYVEYLFTAIVGNQEHK TURTRGS_2563_PE3 NOISO RGENLQDVLPRDIYGRLKRHREYVKLMMPSWMTPD---QHGKGLYADY------------ XENTR202_2_PE20 NOISO QGENLQNVLPRDIYRRLKRHLEYVKLMMPSWMTPD---QRGKGLYADYLFNAIAGNWERK MATCH :. *:. . CONSENSUS ?GENLQDVLPRDIY?RLKRHLEYVKLMMPSWMTPD???QRGKGLYADYLFNAIAGNWERK

AILMEGL192963_1_1_PE4 NOISO RPIWIMLMVNSLTEVVIKSRGVPVLDLYLAQEAERLRKQTGAMEKVEEQCHPLN-GLNFS AILMEGL193692_1_PE3 NOISO RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMRKSTGAVERVEEQCHPLN-GLNFS ANOCA247_1_PE5 NOISO RPVWVMLMVNSLTETDIRSRGVPVLDLYLAQEAERMKKRTGAVERVEEQCHPLN-GLNFS ANOCA861_PE1 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS CALJA14_23_PE19 ISOFORMIN RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLKKQTGAVEKVEEQCHPLN-GLNFS CALJA14_23_PE20 ENSCJAG00000019738 RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLKKQTGAVEKVEEQCHPLN-GLNFS CALJA14_23_PE21 ISOFORMIN RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLKKQTGAVEKVEEQCHPLN-GLNFS CALJA7_88_PE1 NOISO RPVWVMLMVNSLTERDVRFRGVPMLDLYLAQQAEKMKKTTGAVERVEEQCHPLN-GLNFS CANFA15_16_PE5 NOISO RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMRKSTGAVERVEEQCHPLN-GLNFS CANFA17_44_PE12 NOISO RPIWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS CAVPO189_1_PE3 ENSCPOG00000011762 RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMKKSTGAVEQVEEQCHPLN-GLNFS CHICK8_PE524 NOISO RPVWVMLMVNSLTETDIRSRGVPVLDLYLAQEAERMKKTTGAVERVEEQCHPLN-GLNFS CHICKZ_PE728 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS CIOSAREFTIG_97_PE39 NOISO RPIWIMLMINALTKPDIRSRGLPVLDVYLARQAELMGKRTGAIEKVEEQCRPFN-GLNMS DANRE5_1_PE8 NOISO RPVWVMLMVNSLTEADIKTRGVPVLDLYLAQEAERMKKQTGAVEKVEEQCSPLN-TLDFS DANRE8_22_PE1 NOISO RPVWVMLMVNSLTEADVRSRGTPVLDLFLAQEAERLGKQTGAVERVEEQCHPLN-GLNFS FELCAGS_1375_PE2 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLN-GLNF- GASACGROUPVIII_16_PE1 NOISO RPVWVMLMVNSLTEWDVRSRGTPVLDLFLAQEAERMGKVTGAVERVEEQCHPLN-GLNFS GORGO2A_91_PE1 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS HORSE15_20_PE17 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS HORSE2_12_PE1 NOISO RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMRKSTGAVEQVEEQCHPLN-GLNFS HS2_PE2202 ISOFORMIN RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS HS2_PE2203 ENSG00000186854 RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS HS2_PE2204 ISOFORMIN RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS LOXAF17_51_PE4 NOISO RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMKKSTGAVERVEEQCHPLN-GLNFS MACEUGS_7714_PE1 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKRTGAVEKVEEQCHPLN-GLNF- MACMU13_88_PE7 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS MACMU1_53_PE12 NOISO RPVWVMLMVNSLTERDVRFRGVPVLDLYLAQQAEKMKKTTGAVEQVEEQCHPLNNGLNFS MICMUGS_1292_PE2 NOISO RPVWVMLMVNSLTEADITSQGVPVLDLY-AQEAERLRKQTGAVEKVEEQCHLLN-GLHFS MONDO1_736_PE19 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLKKQTGAVEKVEEQCHPLN-GLNFS MONDO2_7_PE11 NOISO RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQEAERMKKRTGAVERVEEQCHPLN-GLNFS MOUSE4_PE1819 NOISO RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMKKSTGAVERVEEQCHPLN-GLNFS NEMVE_5827_PE59 NOISO RPIWVMLMVNSLTESDIKTRGIPVLDQYLALEASRNHKLIGAVENVDEQCKPLN-ALNAS OCHPRGS_3496_PE5 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKPTGAVEKVEEQCHPFN-RLNFS ORNANCONTIG68680_PE1 ENSOANG00000006858 RPVWVMLMVNSLTEADVRSRGVPVLDLFLAQEAERLKKRTGAVERVEEQCLPLN-GLNIS ORNANCONTIG68680_PE2 ISOFORMIN RPVWVMLMVNSLTEADVRSRGVPVLDLFLAQEAERLKKRTGAVERVEEQCLPLN-GLNIS PANTR2A_91_PE5 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS POEGU8_21_PE1 NOISO RPVWVMLMVNSLTETDIRSRGVPVLDLYLAQEAERMKKKTGAVERVEEQCHPLN-GLNFS POEGUZ_4_PE1 ENSTGUG00000000145 RPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS PONPY2A_26_PE13 NOISO RPVWVMLMVNSLTEVDVKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS PTEVAGS_3597_PE1 NOISO RPVWVMLMVNSLTEVNIKSWGVPLLDLYFAQVAERLRKQTGVMEKVEEQCHPLN-GLNFS RABIT2_103_PE7 NOISO RPIWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLN-GLNFS RAT5_PE1104 NOISO RPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMKKSTGAVERVEEQCHPLN-GLNFS SORARGS_5477_PE4 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLN-GLNF- SPETRGS_1659_PE2 NOISO R----------LMEMDIKSWRLPVLDLYLAKEAEWLRKQTGAVEEVEEQCHPLY-GLNLS TURTRGS_2563_PE3 NOISO ------------------------------------------------------------ XENTR202_2_PE20 NOISO RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLKKRTGAVEQVEEQCHPLN-GLNLS MATCH CONSENSUS RPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLN?GLNFS

AILMEGL192963_1_1_PE4 NOISO QVIFALNQTLLQQESLRAGRLQIPYTTEDLIKHYNCGDLSSVIFSHDSSQVPNFINATLP AILMEGL193692_1_PE3 NOISO QVG--------------------------------------------------------- ANOCA247_1_PE5 NOISO QV---------------------------------------------------------- ANOCA861_PE1 NOISO Q-------------------------------------------------VPNFINATLP CALJA14_23_PE19 ISOFORMIN -------------------------------------------------QVPNFINATLP CALJA14_23_PE20 ENSCJAG00000019738 QVIFALNQTLLQQESLRAGSLQNPYTTEDLIKHYNCGDLSSIILSHDSSQVPNFINATLP CALJA14_23_PE21 ISOFORMIN -------------------------------------------------QVPNFINATLP CALJA7_88_PE1 NOISO QVLFALNQTLLQQESVRAGSLQAHYTTEDLIKHYNCGDLNAVIFNHDTSQLPNFINTTLP CANFA15_16_PE5 NOISO QVG--------------------------------------------------------- CANFA17_44_PE12 NOISO Q-------------------------------------------------VPNFINSTLP CAVPO189_1_PE3 ENSCPOG00000011762 -------------------------------------------------QLPNFLNTTLP CHICK8_PE524 NOISO QV---------------------------------------------------------- CHICKZ_PE728 NOISO Q-------------------------------------------------VPNFINATLP CIOSAREFTIG_97_PE39 NOISO QVLFALNHTLTLQEKIRRGKMRLPYSTDDLINTYNCGDLNSLIFGKGTSQIPHLKNSDVE DANRE5_1_PE8 NOISO QVIFALNQTLLQQESVRAGSLQVPYTTEHLITHYNCGDLHSII-SHDTAQVPNFNNVTLR DANRE8_22_PE1 NOISO QVLFALNQTLLQHESLRAGILQGTFTTEDLIAHYNCGDLNSIIFNHDTSQLPHFINSSLP FELCAGS_1375_PE2 NOISO ------------------------------------------------SQVPNFINATLP GASACGROUPVIII_16_PE1 NOISO Q-------------------------------------------------LPHFINSSLP GORGO2A_91_PE1 NOISO QVIFALNQTLLQQESLRAGSLQIPYTTEDLIKHYNCGDLSSVILSHDSSQVPNFINATLP HORSE15_20_PE17 NOISO Q-------------------------------------------------VPNFINATLP HORSE2_12_PE1 NOISO QVLFALNQTLLQHESVRAGSLQAPYTTEDLIKHYNCGDLNAVIFNHDTSQLPNFINTTLP HS2_PE2202 ISOFORMIN -------------------------------------------------QVPNFINATLP HS2_PE2203 ENSG00000186854 QVIFALNQTLLQQESLRAGSLQIPYTTEDLIKHYNCGDLSSVILSHDSSQVPNFINATLP HS2_PE2204 ISOFORMIN QVIFALNQTLLQQESLRAGSLQIPYTTEDLIKHYNCGDLSSVILSHDSSQVPNFINATLP LOXAF17_51_PE4 NOISO QV---------------------------------------------------------- MACEUGS_7714_PE1 NOISO ------------------------------------------------SQVPNFINATLP MACMU13_88_PE7 NOISO Q-------------------------------------------------VPNFINATLP MACMU1_53_PE12 NOISO QVG--------------------------------------------------------- MICMUGS_1292_PE2 NOISO Q-------------------------------------------------IPNFINAMLP MONDO1_736_PE19 NOISO Q-------------------------------------------------VPNFINATLP MONDO2_7_PE11 NOISO QVG--------------------------------------------------------- MOUSE4_PE1819 NOISO QVLFALNQTLLQHESVRAGSLQAPYTTEDLIKHYNCGDLNAVIFNHDTSQLPNFINTTLP NEMVE_5827_PE59 NOISO QV---------------------------------------------------------- OCHPRGS_3496_PE5 NOISO Q-------------------------------------------------VPNFINATLR ORNANCONTIG68680_PE1 ENSOANG00000006858 Q----------------------------------------------------------- ORNANCONTIG68680_PE2 ISOFORMIN QAVS-------------------------------------------------------- PANTR2A_91_PE5 NOISO Q-------------------------------------------------VPNFINATLP POEGU8_21_PE1 NOISO QV---------------------------------------------------------- POEGUZ_4_PE1 ENSTGUG00000000145 Q-------------------------------------------------VPNFINATLP PONPY2A_26_PE13 NOISO Q-------------------------------------------------VPNFINATLL PTEVAGS_3597_PE1 NOISO Q-------------------------------------------------VPNFINSTLQ RABIT2_103_PE7 NOISO Q-----------------------------------------------MEVPNFINATLP RAT5_PE1104 NOISO QVLFALNQTLLQHESVRAGSLQAPYTTEDLIKHYNCGDLNAVIFNHDTSQLPNFINTTLP SORARGS_5477_PE4 NOISO ------------------------------------------------SQVPNFINATLP SPETRGS_1659_PE2 NOISO Q-------------------------------------------------VPNFINAMLQ TURTRGS_2563_PE3 NOISO --------------------------------------------------GPDFINAMLP XENTR202_2_PE20 NOISO QVIFALNQTLLQQENLRAGSVQVPYSTEDLIKHYNCGDLNSIIFNHDSSQVPNFINSTLP MATCH CONSENSUS Q?????????????????????????????????????????????????VPNFINATLP

AILMEGL192963_1_1_PE4 NOISO P--------------QERVTAQEIDSYFRQELIYKRNERMGKRVKALLEEFPDKGFFFAF AILMEGL193692_1_PE3 NOISO ------------------------------------------------------------ ANOCA247_1_PE5 NOISO ------------------------------------------------------------ ANOCA861_PE1 NOISO P--------------HERTTAMEIDSYFRQELIYKRNERMGKRVKDLLEEYPDKSFFFAF CALJA14_23_PE19 ISOFORMIN P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF CALJA14_23_PE20 ENSCJAG00000019738 P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF CALJA14_23_PE21 ISOFORMIN P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF CALJA7_88_PE1 NOISO P--------------HEQVTAQEIDSYFRQELIYKRNERMGKRVMALLQENKDKICFFAF CANFA15_16_PE5 NOISO ------------------------------------------------------------ CANFA17_44_PE12 NOISO P--------------QERVTAQEIDSYFRQELIYKRNERMGKRVKALLEEFPDKGFFFAF CAVPO189_1_PE3 ENSCPOG00000011762 P--------------HEQVTAQEIDSYFRQELIYKRNERMGKRVMTLLRENEDKICFFAF CHICK8_PE524 NOISO ------------------------------------------------------------ CHICKZ_PE728 NOISO A--------------HERITAQEIDSYFRQELIYKRNERMGRRVKDLLEEYPNRSFFFAF CIOSAREFTIG_97_PE39 NOISO NNETGHKLSGVEITTADTAMASEIDEYLKEELIFRRNERMATRVVDLIRRNEDESFFFAF DANRE5_1_PE8 NOISO P--------------SDQVTAQQIDSYFRRELIYKRNERMGRRVTALLQEQPHKTFFFAF DANRE8_22_PE1 NOISO D--------------HERLTAQQIDSYLRQELIYKRNERMARRVSALLQRNPNQSFFFAF FELCAGS_1375_PE2 NOISO P--------------QERVTAQEIDSYFRQELIYKRNERMGKRVKALLEEFPDKGFFFAF GASACGROUPVIII_16_PE1 NOISO A--------------HDRTMALQIDSYFRRELIYKRNERMARRVSDLLQRNPNQTYFFAF GORGO2A_91_PE1 NOISO P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF HORSE15_20_PE17 NOISO P--------------QELITAQEIDSYFRQELIYKRNERMGKRVKALLEEFPDKGFFFAF HORSE2_12_PE1 NOISO P--------------HEQVTAQEIDSYFRQELIYKRNERMGKRVMALLRENEDKICFFAF HS2_PE2202 ISOFORMIN P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF HS2_PE2203 ENSG00000186854 P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF HS2_PE2204 ISOFORMIN P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF LOXAF17_51_PE4 NOISO ------------------------------------------------------------ MACEUGS_7714_PE1 NOISO P--------------QERITAQEIDSYFRQELIYKRNERMGKRVKALLEEYPDKGFFFAF MACMU13_88_PE7 NOISO P--------------QELITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF MACMU1_53_PE12 NOISO ------------------------------------------------------------ MICMUGS_1292_PE2 NOISO P--------------QERITAQEIDSYFRRELIYTRNERMGKRVKARLEEFPDKGSFFAF MONDO1_736_PE19 NOISO P--------------QERITAQEIDSYFRQELIYKRNERMGKRVKALLEEYPDKGFFFAF MONDO2_7_PE11 NOISO ------------------------------------------------------------ MOUSE4_PE1819 NOISO P--------------HEQVTAQEIDSYFRQELIYKRNERMGKRVMALLQENQDKICFFAF NEMVE_5827_PE59 NOISO ------------------------------------------------------------ OCHPRGS_3496_PE5 NOISO P--------------QERITAQEIDSYFRRELIYKRNERMGKRVMALLEQFPDKGFFFAF ORNANCONTIG68680_PE1 ENSOANG00000006858 ------------------------------------------------------------ ORNANCONTIG68680_PE2 ISOFORMIN ------------------------------------------------------------ PANTR2A_91_PE5 NOISO P--------------QERITAQEIDSYLRRELIHKRNERIGKRVKALLEEFPDKGFFFAF POEGU8_21_PE1 NOISO ------------------------------------------------------------ POEGUZ_4_PE1 ENSTGUG00000000145 A--------------HERITAQEIDSYFRQELIYKRNERMGRRVKDLLEEQPDKSFFFAF PONPY2A_26_PE13 NOISO P--------------QERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAF PTEVAGS_3597_PE1 NOISO P--------------QERITAQGIDNYFHQELI-KRNERMGKRVKAVLEELSDKGFFLAF RABIT2_103_PE7 NOISO P--------------QERITAQEIDSYFRRELIYKRNERMGKRVKALLEEFPDKGFFFAF RAT5_PE1104 NOISO P--------------HEQVTAQEIDSYFRQELIYKRNERMGKRVMALLQENQGKICFFAF SORARGS_5477_PE4 NOISO P--------------QERITAQEIDSYFRRELIYKRNERMGKRVKALLEEFPDKGFFFAF SPETRGS_1659_PE2 NOISO P--------------QEHITAQEINSHFCQELIYKWNERMEEQGKALLEEFPDKGFFFVF TURTRGS_2563_PE3 NOISO P--------------AERIAAQEIDSYFRRELIYKRNKRMGKRVKALLEEFPDKGFFFAF XENTR202_2_PE20 NOISO P--------------QERITAQEIDNYFRQELIYKRNERMGKRVKDLLEQFPEKSFFFAF MATCH CONSENSUS P???????????????ER?TAQEIDSYFR?ELIYKRNERMGKRVKALLEE?PDK?FFFAF

AILMEGL192963_1_1_PE4 NOISO GAGHFMGNNTVLDVLRREGYEVEHVPAGRAVNKEKSQS-----------PSSGPTSSAIF AILMEGL193692_1_PE3 NOISO ------------------------------------------------------------ ANOCA247_1_PE5 NOISO ------------------------------------------------------------ ANOCA861_PE1 NOISO GAGHFMGNNTVIDVLRREGYGVDHTSAGQAINSENSHK-----------SSW-----REY CALJA14_23_PE19 ISOFORMIN GAGHFMGNHTVLDVLRREGYEVEHAPAGRPIHKGKSKK-----------TSPRPTPFTIF CALJA14_23_PE20 ENSCJAG00000019738 GAGHFMGNHTVLDVLRREGYEVEHAPAGRPIHKGKSKK-----------TSPRPTPFTIF CALJA14_23_PE21 ISOFORMIN GAGHFMGNHTVLDVLRREGYEVEHAPAGRPIHKGKSKK-----------TSPRPTPFTIF CALJA7_88_PE1 NOISO GAGHFLGNNTVIDILRQAGLEVDHTPAGQAIHSPDPQS-PAPSLEG-TSTSPAPVTPAAA CANFA15_16_PE5 NOISO ------------------------------------------------------------ CANFA17_44_PE12 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPINKEKSPR-----------SSSGPASSTIF CAVPO189_1_PE3 ENSCPOG00000011762 GAGHFLGNNTVIDVLRQAGLEVDHTPAGQAIDR--------------------------- CHICK8_PE524 NOISO ------------------------------------------------------------ CHICKZ_PE728 NOISO GAGHFMGNNTVIDVLRREGYDVEHTPAGQAINKCMPLL-----------YEPN---VTLF CIOSAREFTIG_97_PE39 NOISO GAGHFLGNGSVIDYVTKAGFEIERVDGEFDPRSDTQS--GLTSLKGSWGR---------- DANRE5_1_PE8 NOISO GAGHFLGNNSVIDVLRREGYEVEHTPAGQPLHRRSGWRSADPADT----------D-AA- DANRE8_22_PE1 NOISO GAGHFLGNHSVLDILRQEGYEVEHTPPQEPIIQSWSEREATTLNPT--------EDSFES FELCAGS_1375_PE2 NOISO GAXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXETSRSPL----------SGPASSAIF GASACGROUPVIII_16_PE1 NOISO GAGHFLGNHSVLDILRKDGYEIVHVPPDAREPPPARSG--------EEGAGTSPPDGWPA GORGO2A_91_PE1 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHKGKSKK-----------TSTRPTLSTIF HORSE15_20_PE17 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHSDSPSS-----------PSTQPASSAIF HORSE2_12_PE1 NOISO GAGHFLGNNTVIDVLRQAGLEVEHTPAGQTIHSPAAQS-PAPPPEG-TSASPAPVTPAAA HS2_PE2202 ISOFORMIN GAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHKGKSKK-----------TSTRPTLSTIF HS2_PE2203 ENSG00000186854 GAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHKGKSKK-----------TSTRPTLSTIF HS2_PE2204 ISOFORMIN GAASQ------------------------------------------------------- LOXAF17_51_PE4 NOISO ------------------------------------------------------------ MACEUGS_7714_PE1 NOISO GAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X---XXXXXXXXX MACMU13_88_PE7 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHKGKSKK-----------TSTQPTPSTVF MACMU1_53_PE12 NOISO ------------------------------------------------------------ MICMUGS_1292_PE2 NOISO GAGHFMGENTVLDVLQREGSAVEHAPARRPVNPGSAEL---------------------- MONDO1_736_PE19 NOISO GAGHFMGNDTVLDVLRREGYEVEHTPAGQPINKGKQKV-----------TNK-------- MONDO2_7_PE11 NOISO ------------------------------------------------------------ MOUSE4_PE1819 NOISO GAGHFLGNNTVIDVLRQAGLEVDHTPAGQAIHGPAAVGSPAPPPEITSPASPAPATPAAA NEMVE_5827_PE59 NOISO ------------------------------------------------------------ OCHPRGS_3496_PE5 NOISO GAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------XEKSKKPSSLPAPSSLI ORNANCONTIG68680_PE1 ENSOANG00000006858 ------------------------------------------------------------ ORNANCONTIG68680_PE2 ISOFORMIN ------------------------------------------------------------ PANTR2A_91_PE5 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHN--------------------------- POEGU8_21_PE1 NOISO ------------------------------------------------------------ POEGUZ_4_PE1 ENSTGUG00000000145 GAGHFMGNNTVIDVLRREGYEVEHTPAGQAINK--------------------------- PONPY2A_26_PE13 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHKQKSKK-----------TSTRPTPSTIF PTEVAGS_3597_PE1 NOISO GAGHFMGNNTVLHVLLREGYEVEHAPAGP-INEEKS-----------KSPSSQPPSSGIF RABIT2_103_PE7 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPLNKEKSRR-----------PLSQPAPSATV RAT5_PE1104 NOISO GAGHFLGNNTVIDVLRQAGLEVDHTPAGQAIHSPP-AGSPAPPPEGTSPASRAPATPAAA SORARGS_5477_PE4 NOISO GAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------XEKSSSA-SLLPTPVAF SPETRGS_1659_PE2 NOISO RAGCFMSNNTVLDVLRCKGHE--HALARCPINKESKSPSTLAP-------------LDIF TURTRGS_2563_PE3 NOISO GAGHFMGNNTVLDVLRREGYEVEHAPAGRPINKEKTRN-----------PLSQPAPSAVL XENTR202_2_PE20 NOISO GAGHFLGNNTVIDVLKRYGYDVLHTPAGRSIINNGKGKKNLLPSKFSSSSLPVG----LS MATCH CONSENSUS GAGHF?GNNTV?DVLR??G?EV?H?PAG??I?????????????????????????????

AILMEGL192963_1_1_PE4 NOISO APEVPAGEALAPEAA------SAVHSPLLPHVSPPGSADLGGESGRKFRKKRRRPSPQRR AILMEGL193692_1_PE3 NOISO ------------------------------------------------------------ ANOCA247_1_PE5 NOISO ------------------------------------------------------------ ANOCA861_PE1 NOISO -PSYIISQELHPSQQHPQKEEEDEEDELLPHLLLPESIDLLEKVDKKYKKKKK--KQQ-K CALJA14_23_PE19 ISOFORMIN APKVPSPEVLAPEAV------SSVYSTLPPLVSQPGRADPPSEAVQKFQKKWRR--PQRR CALJA14_23_PE20 ENSCJAG00000019738 APKVPSPEVLAPEAV------SSVYSTLPPLVSQPGRADPPSEAVQKFQKKWRR--PQRR CALJA14_23_PE21 ISOFORMIN APKVPSPEVLAPEAV------SSVYSTLPPLVSQPGRADPPSEAVQKFQKKWRR--PQRR CALJA7_88_PE1 NOISO VPAAPSVTPTAPP--------EDEDPALSPHLLLPDSLSQL---EEFGRQRKWHKRQS-T CANFA15_16_PE5 NOISO ------------------------------------------------------------ CANFA17_44_PE12 NOISO APEEPAVEAPAPAPEAPAA---AARALLPPHASPPGSADLGGEAERKFRKKRRRPRPQ-R CAVPO189_1_PE3 ENSCPOG00000011762 ------------------------------------------------------------ CHICK8_PE524 NOISO ------------------------------------------------------------ CHICKZ_PE728 NOISO APSVPCVEIYTPLA---------------------------------------------- CIOSAREFTIG_97_PE39 NOISO -----------------------------------------GK------NKRKHREKQ-- DANRE5_1_PE8 NOISO ---------LQPFLH------HSRH----HELQLLEGLELLEKVEHKLKKKHR----RNK DANRE8_22_PE1 NOISO VTEW---TSETPE-L------EEISQEELSHMLLPDSLSQLEE---FGRYKHPRKT-HHT FELCAGS_1375_PE2 NOISO VPEVPASEARVPEAG------SAVHSLWPPHVSLPGSAHLGGGAERKFRKKRRRHRPQ-R GASACGROUPVIII_16_PE1 NOISO APSEAGLEADYAEGE------RGLGDDEPPHILLPDSLSQLEE---FGRHKRPRKA-HRG GORGO2A_91_PE1 NOISO APKVPTLEVPAPEAV------SSGHSTLPPLVSRPGSADPPSEAEQRFRKKRRR--SQRR HORSE15_20_PE17 NOISO APEVPAPEALVLEAG------SAVHSLLPTHVSLPGSADLPVEAERKFRKKRR--RPQ-R HORSE2_12_PE1 NOISO IPTAPSATPTTPP--------EEEDPALSPHLLLPDSLSQL---EEFGRQKKWRKRQN-K HS2_PE2202 ISOFORMIN APKVPTLEVPAPEAV------SSGHSTLPPLVSRPGSADTPSEAEQRFRKKRRR--SQRR HS2_PE2203 ENSG00000186854 APKVPTLEVPAPEAV------SSGHSTLPPLVSRPGSADTPSEAEQRFRKKRRR--SQRR HS2_PE2204 ISOFORMIN ------------------------------------------------------------ LOXAF17_51_PE4 NOISO ------------------------------------------------------------ MACEUGS_7714_PE1 NOISO XXXX-XXXXXXXX--------XXXXXX---XX-XXXXXXXX---XXXXXXXXXXXXXX-X MACMU13_88_PE7 NOISO APKVSTPEVPTPEAI------SSVHSTLPTLVSRPGSAHPPSDAEQNCVNIW---GPWRV MACMU1_53_PE12 NOISO ------------------------------------------------------------ MICMUGS_1292_PE2 NOISO ----------------------------------------SGKDEQKSRKRRRRP--Q-- MONDO1_736_PE19 NOISO QPTFQTAYAVHPAPKFSQHML------IFEVCSLSGTLFGPSKMDRKYRKKKK--KQM-K MONDO2_7_PE11 NOISO ------------------------------------------------------------ MOUSE4_PE1819 NOISO VPEATSATPTTPP--------EEEDPVLSPHLLLPDSLSQL---EEFGRQ-KWRKRLN-K NEMVE_5827_PE59 NOISO ------------------------------------------------------------ OCHPRGS_3496_PE5 NOISO APEVLTPEALALEAG------VAARAPLPFHVSPPAKVGLPGEEEHRFQKKRRWP---PR ORNANCONTIG68680_PE1 ENSOANG00000006858 ------------------------------------------------------------ ORNANCONTIG68680_PE2 ISOFORMIN ------------------------------------------------------------ PANTR2A_91_PE5 NOISO ------------------------------------------------------------ POEGU8_21_PE1 NOISO ------------------------------------------------------------ POEGUZ_4_PE1 ENSTGUG00000000145 ------------------------------------------------------------ PONPY2A_26_PE13 NOISO APKVPTLEVPAPEAV------SSVHLTPPPLVSRPGSPDPPSEAEQKFRKKRRR--SQRR PTEVAGS_3597_PE1 NOISO SPKAPTPEALVPGAG------WAAHLLSTPHVLLPRSADLRGEAQRKFQKRRRWP----- RABIT2_103_PE7 NOISO APEVLAPEALAPEAGL------AAHAWLPSHVSPPGSVELPGEPERKFRKKRK--RPQ-R RAT5_PE1104 NOISO VPEATSVTPTTPP--------EEEDPVLSPHLLLPDSLSQL---EEFGRQ-KWRKKLN-K SORARGS_5477_PE4 NOISO DPQVAAPDAPAPEAG------SVAHVRV--PLTESGGLGLPEGTERKF--RKKRRRPP-R SPETRGS_1659_PE2 NOISO ASEVPVLAALALE----------ALSATLPHEPLPGSANQLGSGQ-KFRKKWR------C TURTRGS_2563_PE3 NOISO APEAPAPEAQVPEAG------SAESPLLPLHQPLPRSSYLPGEARRKFRKKRRRPQ---R XENTR202_2_PE20 NOISO APPCTVTSRIKQSIN------SHKDQESLPDILLDDDIDQLDKDE-----RKYKKRKQ-R MATCH CONSENSUS ?P?????????P??????????????????????P?????????????????????????

AILMEGL192963_1_1_PE4 NOISO -QRLRQFSDLWVRLEESAVVPQLQVSVLDRSVCAE------------QQLPHRG-HPSHS AILMEGL193692_1_PE3 NOISO ------------------------------------------------------------ ANOCA247_1_PE5 NOISO ------------------------------------------------------------ ANOCA861_PE1 NOISO KQRLRQFNDLWVRIEE-------------------------------------------- CALJA14_23_PE19 ISOFORMIN -QRLRQFSDLWVRLEESDMVPQLQVPVLDRHISTE------------LRLPLHG-HSHHS CALJA14_23_PE20 ENSCJAG00000019738 -QRLRQFSDLWVRLEESDMVPQLQVPVLDRHISTE------------LRLPLHG-HSHHS CALJA14_23_PE21 ISOFORMIN -QRLRQFSDLWVRLEESDMVPQLQVPVLDRHISTE------------LRLPLHG-HSHHS CALJA7_88_PE1 NOISO HQRPRQFNDLWVRIEDSTTASLPPLPLQPTHSS-GTAKPHFQLSDQLQEQDPPG-PASSS CANFA15_16_PE5 NOISO ------------------------------------------------------------ CANFA17_44_PE12 NOISO RQRLRQFSDLWVRLEESAVVPQLQVPVLERYISAE------------LQLPHHG-HSH-- CAVPO189_1_PE3 ENSCPOG00000011762 ------------------------------------------------------------ CHICK8_PE524 NOISO ------------------------------------------------------------ CHICKZ_PE728 NOISO ------------------------------------------------------------ CIOSAREFTIG_97_PE39 NOISO ----SRFDIPL------------------------------------------------- DANRE5_1_PE8 NOISO LKKQRQFNDLWVRMEDSVTAEAP-PPLIHIINGYITVQTHPQEHERANHDRTFS-GSSSR DANRE8_22_PE1 NOISO HSRPRLFSDLWVRIGDSTTP----HPSIRITNGYVTVEPPQIRQEQQQRLRERLKPLSEP FELCAGS_1375_PE2 NOISO KQRLRQFSDLWVRLEESAEVPQLQVPVLDRHIS-AELQLP-----------RHG-HSRHS GASACGROUPVIII_16_PE1 NOISO HGRPRLFSDLWVRIGD-------------------------------------------- GORGO2A_91_PE1 NOISO -PRLRQFSDLWVRLEESDIVPQLQVPVLDRHISTE------------LRLPRRG-HSHHS HORSE15_20_PE17 NOISO RQQFRQFSDLWVRLDESAVVPQLQVPVVDRHITAE------------LRLPRHG-PSR-- HORSE2_12_PE1 NOISO HQRPRQFNDLWVRIEDSTTASPPPLPLQPTPSP-GTAKPPFQLSDQLQQQEEPG-PTSNS HS2_PE2202 ISOFORMIN -PRLRQFSDLWVRLEESDIVPQLQVPVLDRHISTE------------LRLPRRG-HSHHS HS2_PE2203 ENSG00000186854 -PRLRQFSDLWVRLEESDIVPQLQVPVLDRHISTE------------LRLPRRG-HSHHS HS2_PE2204 ISOFORMIN ------------------------------------------------------------ LOXAF17_51_PE4 NOISO ------------------------------------------------------------ MACEUGS_7714_PE1 NOISO XXXXXXXXXXXXXXXXXXXXAPAPLPRIRIVNGYITVEPL---------LPGHR-RSPHT MACMU13_88_PE7 NOISO QWFLLCLQTLSFSLPPSDVVPQLQVRVLDRHISTE------------LQFPRHG-HSHHS MACMU1_53_PE12 NOISO ------------------------------------------------------------ MICMUGS_1292_PE2 NOISO -QR---QRLPWVRLEESAVAPHLQVPVLDRHISAE------------VQLLRRG----HS MONDO1_736_PE19 NOISO KQRLRQFSDLWVRLEESAPAPLPRIRIVNGYITVE------------PLLPGHR-RSP-- MONDO2_7_PE11 NOISO ------------------------------------------------------------ MOUSE4_PE1819 NOISO HQRPRQFNDLWVRIEDSTTISPPPLPLQPTPSS-ETTKPFVKSSHQLQQQDAVG-PTSSS NEMVE_5827_PE59 NOISO ------------------------------------------------------------ OCHPRGS_3496_PE5 NOISO KQPQRQFSDLWVRLEERLP------PVLDKHVSTE------------LQLPP-------- ORNANCONTIG68680_PE1 ENSOANG00000006858 ------------------------------------------------------------ ORNANCONTIG68680_PE2 ISOFORMIN ------------------------------------------------------------ PANTR2A_91_PE5 NOISO -----------------DIVPQLQVPVLDRHISTE------------LRLPRRG-HSHHS POEGU8_21_PE1 NOISO ------------------------------------------------------------ POEGUZ_4_PE1 ENSTGUG00000000145 ------------------------------------------------------------ PONPY2A_26_PE13 NOISO -QRLRQFSDLWVRLEESDMVPQLQVPVLDRHVSTD------------LRLPRHG-YSHHS PTEVAGS_3597_PE1 NOISO --QWRLFSDLWVLEE--------------------------------------------- RABIT2_103_PE7 NOISO KQRLRQFSDLWVRLEESAAVPQFQVPVLDRHISTE------------LQLLHHG-HSH-- RAT5_PE1104 NOISO HQRPRQFNDLWVRIEDSTTISPPPLPLQPTPSS-ETTKPFVKSSHQLQQQDPVG-PTSSS SORARGS_5477_PE4 NOISO RQRLRQFSDLWVRLEESAVVPQLPVPVLDGHITRLQ-------------LPHHS-HPRHS SPETRGS_1659_PE2 NOISO LMLKQWFNNLWVFLEESAMAPQLQVPVLDRHISAEL------------WFPHHR----HS TURTRGS_2563_PE3 NOISO RQRLRQFSDLWVRLEESAGIPQLQVPVLDRRISAK------------LRLPRPG----QS XENTR202_2_PE20 NOISO KEKHRHFSDLWVRIQESSTDTTPQIRI---INGYITVEPHPREHGKDKYIKAAQ-SVSFS MATCH CONSENSUS ????R?F?DLWVR?E?S????????P??????????????????????????????????

AILMEGL192963_1_1_PE4 NOISO ---QMVASSACLSLWTP--VFWVLVPAFQAETPLL------- AILMEGL193692_1_PE3 NOISO ------------------------------------------ ANOCA247_1_PE5 NOISO ------------------------------------------ ANOCA861_PE1 NOISO ------------------------------------------ CALJA14_23_PE19 ISOFORMIN ---QMVASSACLCLWTP--VFWVLVLAFQTETPLL------- CALJA14_23_PE20 ENSCJAG00000019738 ---QMVASSACLCLWTP--VFWVLVLAFQTETPLL------- CALJA14_23_PE21 ISOFORMIN ---QMVASSACLCLWTP--VFWVLVLAFQTETPLL------- CALJA7_88_PE1 NOISO --------APTLGLLPA--VA------TTVAAHFLLLSLGPS CANFA15_16_PE5 NOISO ------------------------------------------ CANFA17_44_PE12 NOISO -HSQMVASSACLSLWTP--VFWVLVLAFQTETPLL------- CAVPO189_1_PE3 ENSCPOG00000011762 ------------------------------------------ CHICK8_PE524 NOISO ------------------------------------------ CHICKZ_PE728 NOISO ------------------------------------------ CIOSAREFTIG_97_PE39 NOISO ------------------------------------------ DANRE5_1_PE8 NOISO TGPALSALAVCVQMLRL--LL--------------------- DANRE8_22_PE1 NOISO TNPSALDSAAPNPTYALTCFLACLIS------QLLFAS---- FELCAGS_1375_PE2 NOISO ---QMVASSACLSLWTP--VFWVLVLAFQTETPLLQ------ GASACGROUPVIII_16_PE1 NOISO ------------------------------------------ GORGO2A_91_PE1 NOISO ---QMVASSACLSLWTP--VFWVLVLAFQTETPLL------- HORSE15_20_PE17 NOISO -HSQMVASSACLSLWTP--VFWVLVLAFQTETPLL------- HORSE2_12_PE1 NOISO ---SPSRSRPALGLLPA--VA------ASIAAPLLLPTLRSS HS2_PE2202 ISOFORMIN ---QMVASSACLSLWTP--VFWVLVLAFQTETPLL------- HS2_PE2203 ENSG00000186854 ---QMVASSACLSLWTP--VFWVLVLAFQTETPLL------- HS2_PE2204 ISOFORMIN ------------------------------------------ LOXAF17_51_PE4 NOISO ------------------------------------------ MACEUGS_7714_PE1 NOISO ---QTVSNSACLSLWTL--LFWLLTLALQTEITLL------- MACMU13_88_PE7 NOISO ---QMVASSACLSLWTP--VFWVLVLAFQTETPLL------- MACMU1_53_PE12 NOISO ------------------------------------------ MICMUGS_1292_PE2 NOISO HHSRAVASSGCPPLWTP--MSGVLVLAFQTQTPLLW------ MONDO1_736_PE19 NOISO -HVQTVSNSACLSLWTL--LFWLLTLALQTEITLL------- MONDO2_7_PE11 NOISO ------------------------------------------ MOUSE4_PE1819 NOISO --------APTLGLLHA--IT------ASIVAPFLLHSLGPS NEMVE_5827_PE59 NOISO ------------------------------------------ OCHPRGS_3496_PE5 NOISO -HSPMVASSACLSLWTP--ALWVWVLAFPTETRLF------- ORNANCONTIG68680_PE1 ENSOANG00000006858 ------------------------------------------ ORNANCONTIG68680_PE2 ISOFORMIN ------------------------------------------ PANTR2A_91_PE5 NOISO ---QMVASSACLSLWTP--VFWVLVLAFQTETPLL------- POEGU8_21_PE1 NOISO ------------------------------------------ POEGUZ_4_PE1 ENSTGUG00000000145 ------------------------------------------ PONPY2A_26_PE13 NOISO ---QMVASSACLSLWTP--LFWVLVLAFQTETPL-------- PTEVAGS_3597_PE1 NOISO ------------------------------------------ RABIT2_103_PE7 NOISO -HSQMVASSACLSLWTP--VFWVLALVFQAETHLL------- RAT5_PE1104 NOISO --------APSLGLLPA--IT------ASIVAPFLLHTFGPS SORARGS_5477_PE4 NOISO ---QMVASSACLCLWTP--GFWILVLTFQTDTRLL------- SPETRGS_1659_PE2 NOISO HHSQMVAS-TTLSLWTS--AFLGLVVAFPTETSLL------- TURTRGS_2563_PE3 NOISO PHSQMVVSSACLSVWTP--MLWVL--AFQTETTLL------- XENTR202_2_PE20 NOISO ---LS-----IPSAFLL--LAWCFQQVAVLQ----------- MATCH CONSENSUS ???????????L?L????????????????????L???????


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