Alignment of the gene Family HOG000172196 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
ASFUM1_5_PE493 ASFUM1_5_PE493 ------------------------------------------------------------ ASPCL_22_PE60 ASPCL_22_PE60 --------------------------------------------------MKKMMMG--- ASPFC_4_PE487 ASPFC_4_PE487 ------------------------------------------------------------ ASPFL_12_PE60 ASPFL_12_PE60 -----------------------------------------------------MMLS--- ASPNC_13_PE173 ASPNC_13_PE173 ----------------------------------------------------MAILS--- ASPNG_5_PE276 ASPNG_5_PE276 ----------------------------------------------------MAILS--- ASPOR_3_PE545 ASPOR_3_PE545 -----------------------------------------------------MMLS--- ASPTE_6_PE416 ASPTE_6_PE416 -----------------------------------------------------MILN--- CANAW_1_PE509 CANAW_1_PE509 SSTLSQPSTPLHISLISSIVYNLINSLTTNNH---------NKMPKRYIN---------- CANDC_1_PE830 CANDC_1_PE830 -------------------------------------------MNKSYFN---------- CRYNJ_2_PE423 CRYNJ_2_PE423 ----------------------------------------------------MSRIPIY- DEHAN1_2_PE449 DEHAN1_2_PE449 ------------------MSYSKMR---------------------SVTP---------- EMENI_39_PE1207 EMENI_39_PE1207 ------------------------------------------------------------ KLLAC1_5_PE809 KLLAC1_5_PE809 --------------------------MT---------------MSRNYL----------- LACTH_8_PE13 LACTH_8_PE13 -------------------------------------------MGSHYG----------- NEFIS1_317_PE471 NEFIS1_317_PE471 -------------------------------------------------------MG--- NEUCR_193_PE4 NEUCR_193_PE4 --------------------------MTLGNHPADGGGGGGCGSSSSSLSFKVPRVPSYI PENCW_16_PE124 PENCW_16_PE124 --------------------------------------------------------M--- PICPG_4_PE394 PICPG_4_PE394 -------------------------------------------MT--RL----------- PISTI1_6_PE57 PISTI1_6_PE57 ------------------------------------------------------------ PUCGT_34_PE73 PUCGT_34_PE73 -------------------------------------------MTSRWIRFKNLLFV--- YALIP1_7_PE740 YALIP1_7_PE740 -------------------------------------------------------MHHFV YEASTXIV_PE108 YEASTXIV_PE108 -----------------------MTAAN---------------KNIVFG----------- ZYGRO_6_PE667 ZYGRO_6_PE667 -----------------------MYQLN---------------MSLLWR----------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_5_PE493 ASFUM1_5_PE493 -MLDLRGALVALLLASS--VVAHGG----HESVPEG-AAVSKDPI--DSTLWIHMILMGF ASPCL_22_PE60 ASPCL_22_PE60 -FMNLRGVLTALLLVSP--TFAHGG----HETVPDG-AAVSQEPI--DSTLWVHMILMGF ASPFC_4_PE487 ASPFC_4_PE487 -MLDLRGALVAFLLASS--VVAHGG----HESVPEG-AAVSKDPI--DSTLWIHMILMGF ASPFL_12_PE60 ASPFL_12_PE60 -KSYARGLLAVLLLVSP--ALGHGG----HENVPEG-AAISGEPI--DSTLWVHMILMGL ASPNC_13_PE173 ASPNC_13_PE173 -RLGPQGLLAVLLLASP--TLAHGG----HESVPEG-AAISEDPI--DTTLWIHMILMGF ASPNG_5_PE276 ASPNG_5_PE276 -RLGPQGLLAVLLLASP--TLAHGG----HESVPEG-AAISEDPI--DTTLWIHMILMGF ASPOR_3_PE545 ASPOR_3_PE545 -KSYARGLLAVLLLVSP--ALGHGG----HENVPEG-AAISGEPI--DSTLWVHMILMGL ASPTE_6_PE416 ASPTE_6_PE416 -PFNPRGVLAALLLVSP--VLAHGG----HENVPEG-AAISEDPI--DSTLWVHMILMGL CANAW_1_PE509 CANAW_1_PE509 ---PSRCLIILSSFLLS-LVSADEDGMSMDMGDP-S-SRPEFHPINPGSKTFHWL--LTL CANDC_1_PE830 CANDC_1_PE830 ---YSTFLIILSSLLLINADDNNHDGMSMDMDDSSS-SRPEFHPINPGSKTFHWL--LSL CRYNJ_2_PE423 CRYNJ_2_PE423 -------LLALLAYV-----HYAQA----HEHHNVT-EIDTSVPF--DARIYIHMTLQTY DEHAN1_2_PE449 DEHAN1_2_PE449 ---YSAVLVAL-SICMGAIADDDEGH------MHHD-APVEFHPINGGSKTFHWI--LTL EMENI_39_PE1207 EMENI_39_PE1207 ------------------------------------------------------------ KLLAC1_5_PE809 KLLAC1_5_PE809 ---C--------------LLTCMSLAAAMNMDDIEEYTRP--EINAAGSKTFHWL--ASM LACTH_8_PE13 LACTH_8_PE13 ---CPRKLVAYLAI--ALLLVEQETCAGMQMDDTEGLTRP--DIVQAGPKTFHWL--CTL NEFIS1_317_PE471 NEFIS1_317_PE471 -ILDLRGALVALLLASS--VVAHGG----HESVPEG-AAVSKDPI--DSTLWIHMILMGF NEUCR_193_PE4 NEUCR_193_PE4 TTTAATAVLAAAFIPMA--SGHDHH----EDQIPEG-ATISVEPL--DTTLWLHIFLQTF PENCW_16_PE124 PENCW_16_PE124 -AYLRQSLWTLSVLVAS--ALAHGG----HEAVPEG-ESISQDPI--DSTLWTHMILMGL PICPG_4_PE394 PICPG_4_PE394 ---NRSCGLTLVALCFVGLVTADDDH---DSHMDMS-APKEFHPINPRSKTFHWL--LSL PISTI1_6_PE57 PISTI1_6_PE57 ------------------------------MDMDEG-ERKQFHPINPESKTFHWI--LTL PUCGT_34_PE73 PUCGT_34_PE73 -GLAFRFLIANSKVSVV--VVGHGG----DHSSRPP-PSPDSLPISPPKLVIVHIVLQLL YALIP1_7_PE740 YALIP1_7_PE740 RDE---GH-HHHGNTLP---EYEEG----NHDIPEG-QYTSNESV--GAAMWTYVLVTML YEASTXIV_PE108 YEASTXIV_PE108 ---FSRSISAILLICFFFEKVCGDMEHDMGMDDTSGYTRP--EIVQAGSKSFHWL--CTL ZYGRO_6_PE667 ZYGRO_6_PE667 ---L-----RYLLVSL-ALVNAVRAHGDMNPDNLEGLTSP--DIQSAGPRSFHWI--CTV MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_5_PE493 ASFUM1_5_PE493 TFGIIFPL-GMVLG-IVRSRWHVPLQIVGTVIAV-VAYFLGHAHKGRQFG-KNVHASFAN ASPCL_22_PE60 ASPCL_22_PE60 AFGIIFPL-GMVLG-IVRSRWHVPLQIVGTIIAV-VAYFLGHAHKGRKFG-KNVHASFAN ASPFC_4_PE487 ASPFC_4_PE487 TFGIIFPL-GMVLG-IVRSRWHVPLQIVGTVIAV-VAYFLGHAHKGRQFG-KNVHASFAN ASPFL_12_PE60 ASPFL_12_PE60 AFGIIFPL-GMVLG-VVRSRWHVPLQIVGTIVAI-VAYFLGHAHKGRQFS-KNIHASFAN ASPNC_13_PE173 ASPNC_13_PE173 AFGVIFPL-GMVLG-IIRSRWHVPLQIVGTIIAV-LAYFLGHAHKGRQFS-KNVHASFAN ASPNG_5_PE276 ASPNG_5_PE276 AFGVIFPL-GMVLG-IIRSRWHVPLQIVGTIIAV-LAYFLGHAHKGRQFS-KNVHASFAN ASPOR_3_PE545 ASPOR_3_PE545 AFGIIFPL-GMVLG-VVRSRWHVPLQIVGTIVAI-VAYFLGHAHKGRQFS-KNIHASFAN ASPTE_6_PE416 ASPTE_6_PE416 SFGIIFPL-GMVLG-I-----------VGTVIAV-VAYFLGHAHKGRQFS-KNVHASFAN CANAW_1_PE509 CANAW_1_PE509 FILLILPSISTSLAIANKLHWSLFLQYISTGYSIFESMFLDFPDNIDNHE-NKTSKGTSW CANDC_1_PE830 CANDC_1_PE830 FILLILPSISTSLAIANKLHWSLFLQYISTCYSIFESIFLDFPDNINNHE-NKTSKGTSW CRYNJ_2_PE423 CRYNJ_2_PE423 LWAIAFPL-GMVLG-LSKSKYHVPLQSVNTVLSF-IGIYFGHHHGGRQFP-ATVHGFMAK DEHAN1_2_PE449 DEHAN1_2_PE449 ALLLLMPSVSSALAFGNKLHWSLFLQFISTGYSVVESLFLDFPDNSDNHE-NRTSKGTSW EMENI_39_PE1207 EMENI_39_PE1207 ------------------------------------------------------------ KLLAC1_5_PE809 KLLAC1_5_PE809 TFLLLLPSFSTTLTFGGKVYSSLFFQSISCAYCLVEALFLRFPDG-DGIE-NRTSRGCSW LACTH_8_PE13 LACTH_8_PE13 ALLLLLPSVSTALSFAGKLYFSMFLQIVSLAYAVAEAFILRFPDG-DGIE-NRTSRGTAW NEFIS1_317_PE471 NEFIS1_317_PE471 TFGIIFPL-GMVLG-IVRSRWHVPLQIVGTVIAV-VAYFLGHAHKGRQFG-KNVHASFAN NEUCR_193_PE4 NEUCR_193_PE4 VFGILFPT-GMVLG-IVKSRWHVPLQVLATALAL-LGYALGHLHKGRQFVSNNVHASFAN PENCW_16_PE124 PENCW_16_PE124 AFGIIFPT-GMVLG-IIRSRWHVPVQVVGTVIAV-LAYFLGHAHKGRQFD-KNVHASVAN PICPG_4_PE394 PICPG_4_PE394 ALLFMLPSVSAAYCFANRYVVSSIMQIICACYAVFEVLVLSFPDS-DGVE-NRTSVGTGW PISTI1_6_PE57 PISTI1_6_PE57 ALLLVLPSLSSVLAFADRLHWSLLLQCVSTGYSVFESLFLDFPDNVDNHE-NRTSKGTSW PUCGT_34_PE73 PUCGT_34_PE73 TWGILLPM-GVMLG-LGRSRLHGPVQAVAGLLLSLPATSLSHLSARHPYP-ATLHAALGA YALIP1_7_PE740 YALIP1_7_PE740 AFGIMFPI-GLIMG-LARHRYFIPMQIVAAATAV-VGMVFGLTHGGRRYSPNNIALIWGW YEASTXIV_PE108 YEASTXIV_PE108 GFLLLLPSVVTCLSFAGRIYSATLLQCTCAVYAFLEAAVLRFQDN-DGVE-NRTSRGTAW ZYGRO_6_PE667 ZYGRO_6_PE667 LFLLLLPSVVTCLTFAGKIYSAVVFQSVCGIYAILEAAIFRFNDN-NGIE-NRTSRGTAW MATCH CONSENSUS ??????P?????L????????????Q?????????????L????????????????????

ASFUM1_5_PE493 ASFUM1_5_PE493 LLMLMLVVQVVIGLYLKL-----------HLSK-GF-------------------H-GRI ASPCL_22_PE60 ASPCL_22_PE60 LLMILLAVQVVLGLYLKL-----------HLSK-GI-------------------H-GRI ASPFC_4_PE487 ASPFC_4_PE487 LLMLMLVVQVVIGLYLKL-----------HLSK-GF-------------------H-GRI ASPFL_12_PE60 ASPFL_12_PE60 ILMLMMIVQVVIGFYLKL-----------HLSK-GI-------------------H-GRI ASPNC_13_PE173 ASPNC_13_PE173 TLMLMMVVQIVLGVYLKL-----------HLTK-GI-------------------H-GRI ASPNG_5_PE276 ASPNG_5_PE276 TLMLMMVVQIVLGVYLKL-----------HLTK-GI-------------------H-GRI ASPOR_3_PE545 ASPOR_3_PE545 ILMLMMIVQVVIGFYLKL-----------HLSK-GI-------------------H-GRI ASPTE_6_PE416 ASPTE_6_PE416 TLMFMLVAQVVIGFYLKL-----------HLSK-GI-------------------H-GRI CANAW_1_PE509 CANAW_1_PE509 FLSILLGLTIFLGTFINGSNLIINKFY-PHLQTRQNSNSNSNSNSNSNSNSNSNSNSNYE CANDC_1_PE830 CANDC_1_PE830 FLSILLGLTIFIGTFINGSNLIINKFY-PNLTR---------------------FTVNYE CRYNJ_2_PE423 CRYNJ_2_PE423 ILIWVMVIQACLGIFLKL-----------HVSE-K-----------------------KI DEHAN1_2_PE449 DEHAN1_2_PE449 FLSLLLGATVFMGSFINGSNLVINKFY-PHLST------------------------RGQ EMENI_39_PE1207 EMENI_39_PE1207 --MFFLAAQVILGVYLKL-----------HIEK-GI-------------------L-GKF KLLAC1_5_PE809 KLLAC1_5_PE809 ALLLLSGLTFLTGAIYTGSNFLLFNDRIKSALS------------------------HIA LACTH_8_PE13 LACTH_8_PE13 FMLALLGVTVFFGSLATGTGALVQNKRLQSLAS------------------------HTG NEFIS1_317_PE471 NEFIS1_317_PE471 LLMLMLVVQVVIGLYLKL-----------HLSK-GI-------------------H-GRI NEUCR_193_PE4 NEUCR_193_PE4 ILFLMMLAQVVLGVYLKL-----------HLEK-GF-------------------Q-GRI PENCW_16_PE124 PENCW_16_PE124 WLMLLLVAQVVLGFYLKL-----------HLEK-AG-------------------Q-ARI PICPG_4_PE394 PICPG_4_PE394 VLAILYCVTVFFGSLTNGSEFLLRNKQSDQWLS------------------------ALG PISTI1_6_PE57 PISTI1_6_PE57 FLSALLGATIFVGTLINGSNLVINKFY-PHWQS------------------------RGE PUCGT_34_PE73 PUCGT_34_PE73 PLFGLLLLQICLGFFLKS-----------HWLQ-TS----------------------RF YALIP1_7_PE740 YALIP1_7_PE740 CLMVLAGIQVFFAVFLQI-----------PLRT-REGELEENSVLR-----RYPFF-YRV YEASTXIV_PE108 YEASTXIV_PE108 FLVGLTWITLFFGGLAGGTGFLVKSKRLQTFIS------------------------NAG ZYGRO_6_PE667 ZYGRO_6_PE667 VLALLVWTAIFFGGLASGTSVLIKNKKLQAFVS------------------------RTG MATCH . . CONSENSUS ?L??????????G???????????????????????????????????????????????

ASFUM1_5_PE493 ASFUM1_5_PE493 RRFFVVLHGVLGKAMPIVSWTQMLFGGIAANGFCQGDHLGQCLAHFIMGSAFIAYGIMLT ASPCL_22_PE60 ASPCL_22_PE60 RRFFVMLHGVLGKAMPIVSWTQMVFGGIAANGFCQDDHLGQCLAHFIMGSAFIAYGIMLT ASPFC_4_PE487 ASPFC_4_PE487 RRFFVVLHGVLGKAMPIVSWTQMLFGGIAANGFCQGDHLGQCLAHFIMGSAFIAYGIMLT ASPFL_12_PE60 ASPFL_12_PE60 RRVIVVMHGVIGKAMPVVSWAQMLFGGITAMGFCHDDHLGQCLAHFIMGSAFIAYGIMLT ASPNC_13_PE173 ASPNC_13_PE173 RRVIVIAHGVVGKAMPVASWVQMLFGGITAMGFCRDDHLGQCLAHFIMGSAFIAYGILLT ASPNG_5_PE276 ASPNG_5_PE276 RRVIVIAHGVVGKAMPVASWVQMLFGGITAMGFCRDDHLGQCLAHFIMGSAFIAYGILLT ASPOR_3_PE545 ASPOR_3_PE545 RRVIVVMHGVIGKAMPVVSWAQMLFGGITAMGFCHDDHLGQCLAHFIMGSAFIAYGIMLT ASPTE_6_PE416 ASPTE_6_PE416 RRVFVILHGVLGKAMPVASWVQMLFGGITAMGFCRDDHLGQCLAHFIMGSAFIAYGILLT CANAW_1_PE509 CANAW_1_PE509 YGISYKLYKILSFLTVLTGWVRVCMAPVALFGFCYGKHTGQCIAHGIMGSAFILYSFVLS CANDC_1_PE830 CANDC_1_PE830 YGFSYKLYKILSFLTVLTGWVRVCMAPIALFGFCYDKHTGQCIAHGIMGSAFILYSFILS CRYNJ_2_PE423 CRYNJ_2_PE423 RPWVVPFHSVLGKTFPVLGWTQMLFGVATALGFCRGGNLGQCAAHYIMGSAFIGYGAILV DEHAN1_2_PE449 DEHAN1_2_PE449 YGITYKIYKTLSFLVVLTGWVRVCMAPVALFGFCYGIHTGQCIAHGIMGSSFIFYGFVLA EMENI_39_PE1207 EMENI_39_PE1207 RKILVLLHGILGKLMPILSWVQMLFGGITSLGFCRDDHLGQCLAHFIMGSAFIAYGILLT KLLAC1_5_PE809 KLLAC1_5_PE809 STKVEIAHRVLSLLCVLGGWVKICLAPVALFGFCRGKHTGQCIAHGIMGTAFVLYGFVYV LACTH_8_PE13 LACTH_8_PE13 EKTLRYIHRALSFAVVLTGWIKCCLAPVAMFGFCRDKHTGQCIAHGIMGTAFVLYGFVYS NEFIS1_317_PE471 NEFIS1_317_PE471 RRFFVVLHGVLGKAMPIVSWTQMLFGGIAANGFCQGDHLGQCLAHFIMGSAFIAYGIMLT NEUCR_193_PE4 NEUCR_193_PE4 RPFFRILHSINGKAFPLAAWVQMVFGGITALGFCQGDHLGQCLAHFIMGSAFIAYGVLLT PENCW_16_PE124 PENCW_16_PE124 RWIFVLAHGIVGKVMPVLSWAQMLFGGIASLGFCRDDHLGQCLAHFIMGSAFIGYGICLT PICPG_4_PE394 PICPG_4_PE394 HTASRRVYKTLSVFVVLVGWVKVCLAPVALFGFCRGRSTGQCIAHGIMGSSFIWYGFILL PISTI1_6_PE57 PISTI1_6_PE57 YGFTYKIYKTLSFLAVLTGWVRVCMAPVALFGFCYGKHTGQCIAHGIMGSAFILYSFVLS PUCGT_34_PE73 PUCGT_34_PE73 RSLIQLAHSIIGKSFIPLSWLQILLGAVASLSFCYGDHLGQCLAHMIMGSAFVGYGVVML YALIP1_7_PE740 YALIP1_7_PE740 RNVLSKCLLVLACFLPIASWVQFGFIFITMFGWCHEDHLGQCLAHGIMGSSFIAYGCILT YEASTXIV_PE108 YEASTXIV_PE108 EKRLSYIHRGLSFLTVLTGWVKVCLAPVALFGFCREAHTGQCIAHGIMGSAFVLYGFIYV ZYGRO_6_PE667 ZYGRO_6_PE667 ESKLAYVHRALSFASILAGWVKVCISPVAMFGFCREQHTGQCIAHGIMGSSFILYGFIYT MATCH . .* : : : .:* *** ** ***::*: *. CONSENSUS ???????????????????W???????????GFC???H?GQC?AH?IMGSAFI?YG????

ASFUM1_5_PE493 ASFUM1_5_PE493 ILLLVGQYWLRR----------------TGRSQEFFDSLVIAAWGCVNTFTEHRW----G ASPCL_22_PE60 ASPCL_22_PE60 ILLLVGQLWLRR----------------TGRSQEFFDSLVIAAWGCVNTFTEHRW----G ASPFC_4_PE487 ASPFC_4_PE487 ILLLVGQYWLRR----------------TGRSQEFFDSLVIAAWGCVNTFTEHRW----G ASPFL_12_PE60 ASPFL_12_PE60 ILLLVGQFWLRR----------------SGRSQEFFDSLIIAAWGCVNTFTEHRW----G ASPNC_13_PE173 ASPNC_13_PE173 ILLLVGQYWLRR----------------TGRSQEFFDSLIIAAWGCVNTFTEHRW----G ASPNG_5_PE276 ASPNG_5_PE276 ILLLVGQYWLRR----------------TGRSQEFFDSLIIAAWGCVNTFTEHRW----G ASPOR_3_PE545 ASPOR_3_PE545 ILLLVGQFWLRR----------------SGRSQEFFDSLIIAAWGCVNTFTEHRW----G ASPTE_6_PE416 ASPTE_6_PE416 ILLLVGQYWLRR----------------TGRSQEFFDSLVIAAWGCVNTFTEHRW----G CANAW_1_PE509 CANAW_1_PE509 LVLVI--PWIRKHQLLNTSDGGGGGGGATGTSQEFYDSTVMMVWGVVNTFTEHRW----G CANDC_1_PE830 CANDC_1_PE830 LVLVV--PWIRKHQLMTTPNGG--SGGNTGLSQEFYDSTVMMVWGIVNTFTEHRW----G CRYNJ_2_PE423 CRYNJ_2_PE423 IMLNLGGKWLER----------------RGCSQEMLDSSVITAWGIVNTFTEHH-----G DEHAN1_2_PE449 DEHAN1_2_PE449 FVLVI--PWIRQHSNPNINS------DPNRRSQEFYDSSLMCLWGIVNTFTEHRW----G EMENI_39_PE1207 EMENI_39_PE1207 ILLLVGQYWLRR----------------TGRSQEFFDSLVIAAWGCVNTFTEHRW----G KLLAC1_5_PE809 KLLAC1_5_PE809 TVLVL--PWLRNNN--------------GKYSQDFYDSCVMCAWGIVNTFTEHRW----G LACTH_8_PE13 LACTH_8_PE13 MVLVV--PWIRNSQ--------------AEYSQDRIDSWVMCAWGIVNTFTEHRW----G NEFIS1_317_PE471 NEFIS1_317_PE471 ILLLVGQYWLRR----------------TGRSQEFFDSLVIAAWGCVNTFTEHRW----G NEUCR_193_PE4 NEUCR_193_PE4 IVLLVGQLWLRR----------------TGRSQEFFDSAVIAAWGCVNTFTEHRW----G PENCW_16_PE124 PENCW_16_PE124 ILLLVGQYWLRR----------------TGRSQEFFDSLIIAAWGCVNTFTEHRW----G PICPG_4_PE394 PICPG_4_PE394 LVLVI--PWLRLRE--------------TGYSQEFFDSLLMTAWGCVNTFTEHRW----G PISTI1_6_PE57 PISTI1_6_PE57 FVLVV--PWIRTHQLHNSSN---------LKSQEFYDSTVMCVWGIVNTFTEHRW----G PUCGT_34_PE73 PUCGT_34_PE73 SLMEFGKPWLKA----------------HQLSPEYLDCCVITVWGVVNTFTEHGFFFSAG YALIP1_7_PE740 YALIP1_7_PE740 IMLLLGEAWLQR----------------RNVSQEFYDSTIIMLWGIVNTFTEHRW----G YEASTXIV_PE108 YEASTXIV_PE108 LVLVI--PWIRSAQ--------------TSYSQDYVDSWVMCIWGVVNTFTEHRW----G ZYGRO_6_PE667 ZYGRO_6_PE667 LVLVI--PWIRNAK--------------TSYTQDHIDSWIMCIWGIVNTFTEHRW----G MATCH :: . *:. : : *. :: ** ******* * CONSENSUS ??L?????W?R????????????????????SQE??DS?????WG?VNTFTEHRW????G

ASFUM1_5_PE493 ASFUM1_5_PE493 G-PWVHNDLQHTTMGIVWWCAGLLGIWMSRKR---NGRPKRNLIPAIVILLTGYAMSAHP ASPCL_22_PE60 ASPCL_22_PE60 G-PWVHNDLQHTTMGIVWWCAGLLGIWMSRKR---NGRPKRNLIPAIVILLTGYAMSSHP ASPFC_4_PE487 ASPFC_4_PE487 G-PWVHNDLQHTTMGIVWWCAGLLGIWMSRKR---NGRPKRNLIPAIVILLTGYAMSAHP ASPFL_12_PE60 ASPFL_12_PE60 S-DWSHNDLQHTTMGIVWWCAGLLGMWLSRNR---NGRPKRNLIPAIVILLTGYAMSAHP ASPNC_13_PE173 ASPNC_13_PE173 G-PWVHNDLQHTTMGVVWWCAGLLGIWMSRKR---NGRPKRNLIPAIVILLTGYAMSAHP ASPNG_5_PE276 ASPNG_5_PE276 G-PWVHNDLQHTTMGVVWWCAGLLGIWMSRKR---NGRPKRNLIPAIVILLTGYAMSAHP ASPOR_3_PE545 ASPOR_3_PE545 S-DWSHNDLQHTTMGIVWWCAGLLGMWLSRNR---NGRPKRNLIPAIVILLTGYAMSAHP ASPTE_6_PE416 ASPTE_6_PE416 G-PWVHNDLQHTTMGIVWWCAGLLGIWLSRSR---DGRPKRNLIPAIVIGLTGYAMSAHP CANAW_1_PE509 CANAW_1_PE509 RESWSMGDYQHTAMGIIWWGGGLLGMYLSRKN-------HRSFIPALLLIFTGYSMSQHA CANDC_1_PE830 CANDC_1_PE830 RENWSMGDYQHTAMGIIWWSGGLLGMYLSRKN------HHRSFIPALLLIFTGYSMSQHS CRYNJ_2_PE423 CRYNJ_2_PE423 G-PWTHKDMQHTMMGVLWWAGGMLGIFLSRGG-------RRSFIPSVIIIMTGWGMSAHE DEHAN1_2_PE449 DEHAN1_2_PE449 REGWSHGDYQHTAMGIIWWCGGLIGMWLTRKN------NARSFVPALLLIFTGYGMSQHA EMENI_39_PE1207 EMENI_39_PE1207 G-PWVHNDLQHTTMGIVWWCAGLLGIWLSRKR---NGRPKRNLIPAIVILLTGYAMSGHP KLLAC1_5_PE809 KLLAC1_5_PE809 REEWNHGDYQHTAMGIIWWAGGLVGIYLSRDG-------SRTFVPGLLIIVTGWAMSEHS LACTH_8_PE13 LACTH_8_PE13 REDWNHGDYQHTAMGIIWWAGGLLGIFLSRNG-------RRTFVPSLLIIFTGWAMSEHS NEFIS1_317_PE471 NEFIS1_317_PE471 G-PWVHNDLQHTTMGIVWWCAGLLGIWMSRKR---NGRPKRNLIPAIVILLTGYAMSAHP NEUCR_193_PE4 NEUCR_193_PE4 T-AWVRNDWQHTTMGVIWWAAGLAGIWLSKNR---DGTPKRNFIPGFVLLMTGWAMSAHP PENCW_16_PE124 PENCW_16_PE124 S-PWAHNDLQHTTMGIIWWCAGLLGMWLSRTR---SGRPKRNLIPAIVILITGYAMSAHP PICPG_4_PE394 PICPG_4_PE394 REAWSHGDYQHTSMGIIWWCGGLLGLWLTRNG-------ERSYIPALLLMFTGYGMAEHV PISTI1_6_PE57 PISTI1_6_PE57 TEDWSMGDYQHTAMGIIWWSGGLLGMYLSMKN-------RRTFIPSALLVFTGYSMSQHS PUCGT_34_PE73 PUCGT_34_PE73 P-RWTHKDLQHTFLGVMWASGGGLGIYLSRGG-------RRSVMSGLVIIVTGWAFQSHQ YALIP1_7_PE740 YALIP1_7_PE740 Q-PWSHGDYQHTSMGIIWWCAGLVGILLSRKRWVAGSPPMRNHIPSIVLMFTGYAMSEHA YEASTXIV_PE108 YEASTXIV_PE108 REGWSVHDYQHTFMGIIWWTGGILGIFLSRNG-------RRTFVPSLIIIFTGWAMSEHA ZYGRO_6_PE667 ZYGRO_6_PE667 K-SWKMSEYEHTAMGVLWWSGGLLGIFLSRGG-------RRTFIPSLIIVFTGWAMSQHT MATCH * : :** :*::* .* *: :: *. :.. :: .**:.: * CONSENSUS ???W???D?QHT?MG??WW??GLLG???SR??????????R???P??????TG??MS?H?

ASFUM1_5_PE493 ASFUM1_5_PE493 QTLMISTMVHTIFGYTLMAAGFTRIVEIAFVLKDKNTVSLDGS----DPSSFQYLPPFLL ASPCL_22_PE60 ASPCL_22_PE60 QTLMISTMVHTIFGYTLMAAGLTRIIEIAFVLRDRGSVNPDGS----DPNSFQYLTPFLL ASPFC_4_PE487 ASPFC_4_PE487 QTLMISTMVHTIFGYTLMAAGFTRIVEIAFVLKDKNTVSLDGS----DPSSFQYLPPFLL ASPFL_12_PE60 ASPFL_12_PE60 QFLEISTMIHTIFGYTLMAAGLTRIIEISFVLKDRSTLSLDGS----EPNSFQYLPPFLL ASPNC_13_PE173 ASPNC_13_PE173 QTLMISTMIHSIFGYTLMAAGFTRIIEISFVLRDKGSVSPDGS----DPNSFQYLTPFLL ASPNG_5_PE276 ASPNG_5_PE276 QTLMISTMIHSIFGYTLMAAGFTRIIEISFVLRDKGSVSPDGS----DPNSFQYLTPFLL ASPOR_3_PE545 ASPOR_3_PE545 QFLEISTMIHTIFGYTLMAAGLTRIIEISFVLKDRSTLSLDGS----EPNSFQYLPPFLL ASPTE_6_PE416 ASPTE_6_PE416 QTLMISTMIHTIFGYTLMAAALTRIIEISFVLRDKSTVSMDGS----NPNSFQYLTPFLL CANAW_1_PE509 CANAW_1_PE509 QHLIISTKVHSVFGISLMGAGITRIIEISFLLNDKSCHSS--G----QILSFQYLPPFCL CANDC_1_PE830 CANDC_1_PE830 QHLMISTKVHSVFGIALMGAGITRIIEISFLLKDKSCHPS--G----QILSFQYFPPFCL CRYNJ_2_PE423 CRYNJ_2_PE423 QALMISSKIHALFGYALISAGVLRIVEICFVLNDKPTPSN--G----AIRVFQHLPPYLL DEHAN1_2_PE449 DEHAN1_2_PE449 QHLEISTKVHAMFGLALMGGGFTRIIEISFVLQDKGSSDS--G----KILSFQHMPPFCL EMENI_39_PE1207 EMENI_39_PE1207 QHSMISTMIHKIFGYTLMAAGLTRIIEISFVLRDRSSVSADGS----DPNSFQYLTPFLL KLLAC1_5_PE809 KLLAC1_5_PE809 QKLIISTKVHYLFGLVLMSGGALRIIEIAFLLRDRRT--D--K----HIHSFQYLPPFCL LACTH_8_PE13 LACTH_8_PE13 QKLIISTKVHALFGLVLMAGGALRIVEISFLLRDRRA--A--S----EILSFQYLAPFCL NEFIS1_317_PE471 NEFIS1_317_PE471 QTLMISTMIHSIFGYTLMAAGFTRIIEIAFVLKDKNTVSLDGS----DPNSFQYLPPFLL NEUCR_193_PE4 NEUCR_193_PE4 QELMISAMTHKMFGYSLMGAGLTRIIEISFILKDKPAVSDQGY----ETHSFQYVPVFLL PENCW_16_PE124 PENCW_16_PE124 QSLMISTMIHSIFGYTLMAAGLTRIIEISFVLKDKPAL----S----EPNSFQYLTPFLL PICPG_4_PE394 PICPG_4_PE394 QKLQISTKVHSFFGLALIGGGLARIVEISFVLRDKRH--D--S----KVHSFQYLPSFAL PISTI1_6_PE57 PISTI1_6_PE57 QHLEISTKVHSLFGLALMGAGVTRVIEISFLLHDKACSET--G----RILSFQYMPPFCL PUCGT_34_PE73 PUCGT_34_PE73 QSLEISTRIHGAFGATLMAAGLVKIIT---VLRRAPAVSDHLPPPHLGLDPLDHLTPLLL YALIP1_7_PE740 YALIP1_7_PE740 QHLEVSTKVHAFFGWALILAGLTRIIEISFVLKDGPSKL---A----VAKAWQFLPPFLL YEASTXIV_PE108 YEASTXIV_PE108 QHLIISTKVHNMFGLVLMCGGALRIIEISFLLRDKRT--L--D----KIHSFQYLAPFCL ZYGRO_6_PE667 ZYGRO_6_PE667 QSLVISTKVHFLFGIVLMFGGALRIVEIAFLLKDRRT--L--D----KIQSFQYLPPFCL MATCH * :*: * ** *: .. ::: :*. :... * CONSENSUS Q?L?IST??H??FG??LM??G??RI?EI?F?L?D????????????????SFQYL?PF?L

ASFUM1_5_PE493 ASFUM1_5_PE493 YASGFLFMGATEEQMQLLHDAGITHVSYVLILYSIAFILFLF------------------ ASPCL_22_PE60 ASPCL_22_PE60 YASGFLFMGATEEQMQLLHNAGITHVSYILILYSIAFILFLF------------------ ASPFC_4_PE487 ASPFC_4_PE487 YASGFLFMGATEEQMQLLHDAGITHVSYVLILYSIAFILFLF------------------ ASPFL_12_PE60 ASPFL_12_PE60 YASGFLFMGATEEQMQLLHDAGITHVSYVLILYSIAFVLFLF------------------ ASPNC_13_PE173 ASPNC_13_PE173 YASGFLFMGATEEQMQLLNDAGITHVSYVLILYSIAFILFLC------------------ ASPNG_5_PE276 ASPNG_5_PE276 YASGFLFMGATEEQMQLLNDAGITHVSYVLILYSIAFILFLC------------------ ASPOR_3_PE545 ASPOR_3_PE545 YASGFLFMGATEEQMQLLHDAGITHVSYVLILYSIAFVLFLF------------------ ASPTE_6_PE416 ASPTE_6_PE416 YASGFLFMGATEEQMQLLHQAEITHVSYILILYSIAFILFLF------------------ CANAW_1_PE509 CANAW_1_PE509 TLAGVLFMGATEEQLQLVHDLGSDHSAYILVVSAAAFTIFLW------------------ CANDC_1_PE830 CANDC_1_PE830 TLAGILFMGATEEQLQLVHDLGSDHSAYILVVSAAAFMIFLW------------------ CRYNJ_2_PE423 CRYNJ_2_PE423 VLGGTLFMSATDEEMRNADSLGVDHVTYALFDFSLSFLIYLV------------------ DEHAN1_2_PE449 DEHAN1_2_PE449 ILAGILFMSANEEQLILVNDLGADHSAYILVVTGAAFIIYLW------------------ EMENI_39_PE1207 EMENI_39_PE1207 YASGFLFMGATEEQMMLLENAGITHVSYVLILYSIAFILFLF------------------ KLLAC1_5_PE809 KLLAC1_5_PE809 ICSGILFMGANEEQLILVLRLGADHGAYSLILISGAFLVFLW------------------ LACTH_8_PE13 LACTH_8_PE13 VCSGVLFMGANEEQLQLVLRLGADHSAYSLVAISAAFVVYLW------------------ NEFIS1_317_PE471 NEFIS1_317_PE471 YASGFLFMGATEEQMQLLHDAGITHVSYVLILYSIAFILFLF------------------ NEUCR_193_PE4 NEUCR_193_PE4 YASGFLFMSATEEQMALVAGSGIDHVAYVLIIYSMAFILFLF------------------ PENCW_16_PE124 PENCW_16_PE124 YASGFLFMGATEEQMLLLHNAGVTHVSYVLILYSIAFIVFLCKLIPYPPLIFSGTPTHSS PICPG_4_PE394 PICPG_4_PE394 VEAGVLFMGATEEQLQLVKDLGADHSSYILVVSGAAFMIQLW------------------ PISTI1_6_PE57 PISTI1_6_PE57 TLAGILFMSATEEQLQLVHDLGSDHSAYILVVSSAAFLIFLW------------------ PUCGT_34_PE73 PUCGT_34_PE73 TISGVMFMSATEEQLLLISRIGVDHATYILGQASLGCLLYLY------------------ YALIP1_7_PE740 YALIP1_7_PE740 VESGICFMGATEEQMAYLNDAGIDHSSYLLTLSSAAFLVYFLFL---------------- YEASTXIV_PE108 YEASTXIV_PE108 VCSGLLFMGANEEQLILVLRLGGDHSAYVLIIVSGAFLVYFW------------------ ZYGRO_6_PE667 ZYGRO_6_PE667 VCSGVLFMGATEEQLELVLRFKAGYSSYSLLLISGSFMVYLW------------------ MATCH .* **.*.:*:: : :* * . . : : CONSENSUS ???G?LFM?ATEEQ??L????G??H??Y?L???S?AF???L???????????????????

ASFUM1_5_PE493 ASFUM1_5_PE493 ---VNILLHIYAVHAWPNSAKPSAHSRSSSTTD----------------TVQDSTYINGH ASPCL_22_PE60 ASPCL_22_PE60 ---VNILLHIYAVHAWPESAKFPSRSSA----S----------------DRSEDTYVNGH ASPFC_4_PE487 ASPFC_4_PE487 ---VNILLHIYAVHAWPNSAKPSAHSRSSSTTD----------------PVQDSTYINGH ASPFL_12_PE60 ASPFL_12_PE60 ---VNILLHIYAVHVWPDSGKKLPARSSSEEEEA------------QGATHANGSFLNGH ASPNC_13_PE173 ASPNC_13_PE173 ---KTTSLPPKNQRT---TLTPPPTQSSTCSCT--------------S-----TPSMHGP ASPNG_5_PE276 ASPNG_5_PE276 ---KTTSLPPKNQRT---TLTPPPTQSSTCSCT--------------S-----TPSMHGP ASPOR_3_PE545 ASPOR_3_PE545 ---VNILLHIYAVHVWPDSGKKLPARSSSEEEEA------------QGATHANGSFLNGH ASPTE_6_PE416 ASPTE_6_PE416 ---VNVLLHIYAVHAWPESTKPSNARESLDAEP----------------EQRPSRFMNGH CANAW_1_PE509 CANAW_1_PE509 ---IQLVIMFYLRLVGYN--EDGELGQ--------------------------------- CANDC_1_PE830 CANDC_1_PE830 ---IQLLIMFYLRLVGYN--EDGELGL--------------------------------- CRYNJ_2_PE423 CRYNJ_2_PE423 ---ITFLVHLYSNSGRNALQKENSGEEIFDSERA-E--------------------EHGY DEHAN1_2_PE449 DEHAN1_2_PE449 ---MLLLLSLYLHLVGYD--ENGELGL--------------------------------- EMENI_39_PE1207 EMENI_39_PE1207 ---VNILLHIYAVHAWPESADPAAHSHSRISTDISDQGPSGSIALPNGPGSSRFTHVNGH KLLAC1_5_PE809 KLLAC1_5_PE809 ---QLLCLNFYQRLIEQK--SGSFLDN--------------------------------- LACTH_8_PE13 LACTH_8_PE13 ---ILLCLELYLKLVKLA--EKGPLDS--------------------------------- NEFIS1_317_PE471 NEFIS1_317_PE471 ---VNILLHIYAVHAWPNSAKPSAHSRSSSTTD----------------PVQDSTFINGH NEUCR_193_PE4 NEUCR_193_PE4 ---VNILIHLYDRGANADGLNKNTSA----------QHGNGAIRLNGR--------ATST PENCW_16_PE124 PENCW_16_PE124 LPVVNILLHIYAVHAWPNSESTNQDGPMYS-----------------------TLNGNAN PICPG_4_PE394 PICPG_4_PE394 ---FLLILELYLKLATSDFASNGEYT---------------------------------- PISTI1_6_PE57 PISTI1_6_PE57 ---NQLLLALYLRLVGYD--ENGELSG--------------------------------- PUCGT_34_PE73 PUCGT_34_PE73 ---LNLLIHFYRRAVDPRSSSGLAVPDQLLDDR-------------------------GH YALIP1_7_PE740 YALIP1_7_PE740 -----SLIMLYKYLSGTQLTSRDSH-------------------------------RGQH YEASTXIV_PE108 YEASTXIV_PE108 ---MIACLEFYLYLLEKG--KQGFLPK--------------------------------- ZYGRO_6_PE667 ZYGRO_6_PE667 ---ILICLEFYLHLVRAT--EDGLFYG--------------------------------- MATCH : CONSENSUS ??????????Y?????????????????????????????????????????????????

ASFUM1_5_PE493 ASFUM1_5_PE493 ARSA--SETQQVHD---------AEAFELQGLISDEEDE--DVPG--N---RNHSMGPRK ASPCL_22_PE60 ASPCL_22_PE60 ARSA--SETQQIDD---------AEAFELQGLISDEEDDD-HRPG--N---RNNALGPRK ASPFC_4_PE487 ASPFC_4_PE487 ARSA--SETQQVHD---------AEAFELQGLISDEEDE--DVPG--N---RNHSMGPRK ASPFL_12_PE60 ASPFL_12_PE60 VRSN--SETQHIHD---------AEAYELEGLISDEEDDSK--AA--A---DSHTMGSQR ASPNC_13_PE173 ASPNC_13_PE173 --NP--HKRLPIRA---------LPALQMPARAHPAID---RPPT--A---AS------- ASPNG_5_PE276 ASPNG_5_PE276 --NP--HKRLPIRA---------LPALQMPARAHPAID---RPPT--A---AS------- ASPOR_3_PE545 ASPOR_3_PE545 VRSN--SETQHIHD---------AEAYELEGLISDEEDDSK--AA--A---DSHTMGSQR ASPTE_6_PE416 ASPTE_6_PE416 ARST--AEAQHIND---------AEAFELQGLISDEEEDDNKASG--A---GNHTMGPRK CANAW_1_PE509 CANAW_1_PE509 Q--QQHHHQYQSVD---------VEEFELGDLSEEEEEEEEDQSGSTN--NHHRELDTPP CANDC_1_PE830 CANDC_1_PE830 QGQGQGHHQYQSVD---------VEEFELGDISDDYEEE---GSGST---NNHHELDTPS CRYNJ_2_PE423 CRYNJ_2_PE423 AKVPTEQREQIRGDNDLDGDGDGPEAYEMADRDSSGESEAVKIGG----EDEVDWMGRRG DEHAN1_2_PE449 DEHAN1_2_PE449 GPN-SNYQNINTHD---------AEEFELGDLSEGETDEPSRSPTANQ--Q--------- EMENI_39_PE1207 EMENI_39_PE1207 ARTP--SEAQRIQD---------AETFELQGLISDEEEDEDKVPPYEG---RRHGPGPRK KLLAC1_5_PE809 KLLAC1_5_PE809 ------H--HSEDA---------VLEFSLEDVREA------------------------- LACTH_8_PE13 LACTH_8_PE13 Y---TNN--RGLES---------LTEFELDDVDGENHETVSRN----------------- NEFIS1_317_PE471 NEFIS1_317_PE471 ARSA--SETQQVHD---------AEAFELQGLISDEEDE--DVPG--N---RNHVMGPRK NEUCR_193_PE4 NEUCR_193_PE4 NPVA--QQQQQLRD---------AGEFELEGLMSDEEDDDEVAARRNLLKNEGEGLGVAS PENCW_16_PE124 PENCW_16_PE124 GRAR--SNSQQIQD---------AEAFELHGLISDDEEGP--------------SMGPRK PICPG_4_PE394 PICPG_4_PE394 ------------LA---------DEEFELSDLSPVNTHE--------------------- PISTI1_6_PE57 PISTI1_6_PE57 SGEYESVHA---RQ---------AEDFELGDLSEDDTPVGSGGSG--------------- PUCGT_34_PE73 PUCGT_34_PE73 NKER-----EGSRD-------ALYERLSLESFTDPQLDRPHRDSSSSSFDLNHHQS---- YALIP1_7_PE740 YALIP1_7_PE740 VPLATEEEELGLND-------EEADKFEI-----DDEEDPSE----------GSSSGRRD YEASTXIV_PE108 YEASTXIV_PE108 S---YEL--EEENN---------NVSFELDNISNEDVDEDTTPFNV-------------- ZYGRO_6_PE667 ZYGRO_6_PE667 Y---SSI--ANVHP---------ETEFELDDAIQEEQQSDSVEPGRLE--T--------- MATCH .: CONSENSUS ???????????????????????????EL???????????????????????????????

ASFUM1_5_PE493 ASFUM1_5_PE493 AEDEESTPLVGKEASSA- ASPCL_22_PE60 ASPCL_22_PE60 TEDEESAPLVAKETSSS- ASPFC_4_PE487 ASPFC_4_PE487 AEDEESTPLVGKEASSA- ASPFL_12_PE60 ASPFL_12_PE60 VTDEESSPLVRKETTRG- ASPNC_13_PE173 ASPNC_13_PE173 ------------------ ASPNG_5_PE276 ASPNG_5_PE276 ------------------ ASPOR_3_PE545 ASPOR_3_PE545 VTDEESSPLVRKETTRG- ASPTE_6_PE416 ASPTE_6_PE416 AEDEESAPLVGRDSSSRP CANAW_1_PE509 CANAW_1_PE509 SSD-----DRNKD----- CANDC_1_PE830 CANDC_1_PE830 LSD-----DRNKD----- CRYNJ_2_PE423 CRYNJ_2_PE423 PVNL-------------- DEHAN1_2_PE449 DEHAN1_2_PE449 ------------------ EMENI_39_PE1207 EMENI_39_PE1207 AEDEESAPLFRKDRE--- KLLAC1_5_PE809 KLLAC1_5_PE809 ------------------ LACTH_8_PE13 LACTH_8_PE13 ------------------ NEFIS1_317_PE471 NEFIS1_317_PE471 AEDEESAPLVGKEASSA- NEUCR_193_PE4 NEUCR_193_PE4 PGTT----AARR------ PENCW_16_PE124 PENCW_16_PE124 NSDEELGKEETRH----- PICPG_4_PE394 PICPG_4_PE394 ------------------ PISTI1_6_PE57 PISTI1_6_PE57 ------------------ PUCGT_34_PE73 PUCGT_34_PE73 ------------------ YALIP1_7_PE740 YALIP1_7_PE740 D-GFELSLLRGK------ YEASTXIV_PE108 YEASTXIV_PE108 ------------------ ZYGRO_6_PE667 ZYGRO_6_PE667 ------------------ MATCH CONSENSUS ??????????????????


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