Alignment of the gene Family HOG000220883 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL192563_1_1_PE3 NOISO KPSITSLQMS-DDIDWLHSCRGVCKVDLYSPKEQQDQDRKVICFVDVST--LNVEDKDCK AILMEGL192757_1_1_PE6 NOISO ---------MSDRVDWLQSQNGVCKVDVYSPGDSQPQDWKM------------------- ANOCA41_2_PE10 NOISO ------TNSMAQETDWLHSQTGLCKVNLYSPEGQSDRDRKVICFVDVAS--LNIKD--KK ANOCA55_2_PE10 NOISO ------------------------------------------------------------ BOVIN5_115_PE4 NOISO ---------MSDRVDWLQSQNGVCKVDVYSPGDSQPQDWKM------------------- BOVINX_56_PE6 NOISO --------MS-DDIDWLHSRRGVCKVDLYSPRGQQDQDRKVICFVDVST--LSMEDKDSK CALJA9_18_PE6 NOISO ---------MSDKVDWLQSQNGVCKVDVYSPGDSQAQGWEM------------------- CALJAX_49_PE37 ENSCJAG00000003006 MMACFDTAMMFDDIDWLHSSRSMCKVDLYKPAEQQDQDRKVVCFVDVST--VNVEDKDCK CALJAX_49_PE38 ISOFORMIN ---------MFDDIDWLHSSRSMCKVDLYKPAEQQDQDRKVVCFVDVST--VNVE----- CANFA27_45_PE5 NOISO ---------MSDKVDWLQSQNGVCKVDVYSPGDSQLQDWKM------------------- CANFAX_44_PE4 NOISO IAYSATTKMS-DDIDWLHSRRGVCKVDLYSPTGQQDQDRKVICFVDVST--LNVEDKDSK CAVPO107_3_PE7 NOISO ---------MSNKVNWLQSQNGVCKVDVYSPGEGQAQDWKT------------------- CAVPO158_3_PE2 NOISO -----------------------------------------ICFVDVST--LNAEDKDSK CHOHOGS_1972_PE1 NOISO ---------MSDRVDWLQSQNGVCKVDVYSPGDNHPQDWKM------------------- DIPORGS_3763_PE1 NOISO ISLCDTTKMS-DDIDWLHSRRGVCKVDLYSPKGQQDQERKVICFVDVST--LNVEDKDSK DIPORGS_92_PE2 NOISO ---------MADKVDWLQSQNGVCKVDVYSPGDSQPQEWKM------------------- ECHTEGS_126_PE2 NOISO ---------MSERVDWLQSQNGVCKVDAYSPEDGQAQEWKP------------------- ERIEUGS_141_PE2 NOISO ----------MSEVDWLQSQNGVCKVDVYTPYDSQPQDWKI------------------- GORGO12_5_PE11 NOISO ---------MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKM------------------- GORGOX_53_PE5 NOISO MAYSDTTMMS-DDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVST--LNVEDKDYK HORSE6_34_PE8 NOISO ---------MSDRVDWLQSQNGVCKVDVYSPGDSQPQDWRL------------------- HORSEX_41_PE23 ISOFORMIN -------QMS-DHIDWLHSHRDVCKVDLYSQTGQQDQRRKVICLWWIVSTLASRKIKDSK HORSEX_41_PE24 ENSECAG00000024064 --------MS-DHIDWLHSHRDVCKVDLYSQTGQQDQRRKVICLWWIVSTLASRKIKDSK HS12_PE132 NOISO ---------MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKM------------------- HSX_PE989 ENSG00000147081 MAYSDTTMMS-DDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVST--LNVEDKDYK HSX_PE990 ISOFORMIN --------MS-DDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVST--LNVEDKDYK HSX_PE992 ISOFORMIN --------MS-DDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVST--LNVEDKDYK HSX_PE994 ISOFORMIN --------MS-DDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVST--LNVEDKDYK LOXAF15_51_PE10 NOISO ---------MSDRVDWLQSQNGVCKVDIFSPEDGQSQDWRM------------------- LOXAF56_1_PE2 NOISO RSLSFSFQMS-DDIDWLHSRRGVCKVDLYSPTGQQDQDRKVICFVDVST--LNVEDKDAK MACEUGS_5645_PE1 NOISO ALYHPATAKMSDDIDWLHSRRGVCKVDLYSPTGQQDQDRKVICFVDVST--LNVEDKDKX MACMU11_5_PE11 NOISO ---------MADKVDWLQSQNGVCKVDVYSPGDNQAQDWKM------------------- MACMUX_49_PE3 ENSMMUG00000023060 ------------------------------------------------------------ MACMUX_49_PE4 ISOFORMIN ------------------------------------------------------------ MICMUGS_1141_PE1 NOISO ---------MSDRVDWLQSQNGVCKVDVYSPGDGQPQDWRM------------------- MONDO8_118_PE12 ENSMODG00000018285 ---------SSDKVDWLQSQSGVCKVDVYTPGEGQPQDWKM------------------- MONDO8_118_PE13 ISOFORMIN -----------------------------------SLSAFK------------------- MONDO8_118_PE14 ISOFORMIN ----------------------------------------K------------------- MONDOX_75_PE19 ENSMODG00000011265 -HLSFVSFQMSDDIDWLHSRRGVCKVDLYSPTGQQDQDRKVICFVDVST--LIVYDKDNK MONDOX_75_PE20 ISOFORMIN ----FVSFQMSDDIDWLHSRRGVCKVDLYSPTGQQDQDRKVICFVDVST--LIVYDKDNK MONDOX_75_PE21 ISOFORMIN ---------MSDDIDWLHSRRGVCKVDLYSPTGQQDQDRKVS------------------ MONDOX_75_PE22 ISOFORMIN -------------IDWLHSRRGVCKVDLYSPTGQQDQDRKV------------------- MOUSE6_PE2191 NOISO ---------MADRVDWLQSQSGVCKVGVYSPGDNQHQDWKM------------------- MOUSEX_PE25 ENSMUSG00000050089 IAYCGTTTMS-DDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVST--LNVEDKDSK MOUSEX_PE26 ISOFORMIN --------MS-DDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVST--LNVEDKDSK MOUSEX_PE27 ISOFORMIN --------MS-DDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVST--LNVEDKDSK MYOLUGS_84_PE2 NOISO ---------MSERVDWLQSQNGVCKVDVYSPGDSQPQDWKM------------------- ORNANULTRA315_PE1 ENSOANG00000013980 ---------MADDIDWLHSRRGVCKVDLYSPTGQQDQDRKV------------------- ORNANULTRA315_PE2 ISOFORMIN ---------MADDIDWLHSRRGVCKVDLYSPTGQQDQDRKVICFVDVSA----------- OTOGAGS_1660_1_PE8 NOISO ------------------------------------------------------------ PANTR12_5_PE12 NOISO ---------MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKT------------------- PANTRX_50_PE18 NOISO --------MS-DDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVST--LNVEDKDYK PIG5_63_PE6 NOISO ---------MSDRVDWLQSQNGVCKVDVYSPGDSQAQDWKM------------------- PIGX_44_PE24 NOISO --------MS-DGIDWLHSHRGMCKVDLYSPTGQQDQDRKVICFVDVST--LNVEDKDSK PONPY12_5_PE10 NOISO ---------MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKM------------------- PONPYX_51_PE6 NOISO MAYSDTTMMS-DDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVST--LNVEDKDYK PROCAGS_115_PE2 NOISO ---------MSNKVDWLQSQNGVCKVDKFSPEDGEAQDWKM------------------- PTEVAGS_177_PE4 NOISO ---------MSDRVDWLQSQNGVCKVDIYSPGESQPQDWKI------------------- RABIT8_32_PE14 NOISO ---------MSERVDWLQSQNGVCKVDVYSPGDNQTQDWKM------------------- RAT4_PE1735 NOISO ---------MADRVDWLQSQSGVCKVGVYSPGDNQHQDWKM------------------- RATX_PE275 NOISO IAYCGTTKMS-DDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVST--LNVED-DSK SORARGS_3987_PE1 NOISO ---------MSDDIDWLHSRRGVCKVDLYSPTGQQDQERKVICFVDVST--LNVEDKDSK SPETRGS_89_PE2 NOISO ---------MSERVDWLQSQNGVCKVDVYSPGDSQPQDWKM------------------- TARSYGS_2113_PE1 NOISO ---------MSDRIDWLQSQSEVCRVDVYSPGDNQSPKWKL------------------- TUPGBGS_81_PE2 NOISO ---------MTDRVDWLQSQNGVCKVDVYSPGDNQPHDWKI------------------- TURTRGS_2687_PE3 NOISO IAYSDTTKMSDNNIDWLHSHRGMCKVDLYSPTGQQDQDQKVIYFVDVST--LNMEDKDFK TURTRGS_791_PE4 NOISO ---------MSDRVDWLQSQTGVCKVDVYSPGDDLPQDWKM------------------- MATCH CONSENSUS ??????????????DWL?S??GVCKVD?Y?P???Q?Q??K????????????????????

AILMEGL192563_1_1_PE3 NOISO DAAGSSSEGDLNLGNLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDL AILMEGL192757_1_1_PE6 NOISO -------------------------------------------EASTDPIRVLSWLRRDL ANOCA41_2_PE10 NOISO KRIPCPPDPALDLRNLEEKEVIVIKDKEGDHHSNSEGAVCLFKQGSSDEVNVVSWLSNDL ANOCA55_2_PE10 NOISO ------------------------------------------------------------ BOVIN5_115_PE4 NOISO ----------------------------------SDESLSIFKEASHDPIRVLSWLRRDL BOVINX_56_PE6 NOISO DAAGCSSEGDLNLENLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPLSVFNWLLNDL CALJA9_18_PE6 NOISO -------------------------------------------DTSTDPVRVLSWLRRDL CALJAX_49_PE37 ENSCJAG00000003006 DASGSSSQDSLNLENMEEKEIIMIKDAEKKDQSKTEGSVCLFKQDSSDPISVLHWLLSDL CALJAX_49_PE38 ISOFORMIN -----------------EKEIIMIKDAEKKDQSKTEGSVCLFKQDSSDPISVLHWLLSDL CANFA27_45_PE5 NOISO -------------------------------------------EASTDPIRVLSWLRRDL CANFAX_44_PE4 NOISO DAAGSSSEGDLNLGNLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDL CAVPO107_3_PE7 NOISO -------------------------------------------EAPTDPVRVLSWLRRDL CAVPO158_3_PE2 NOISO GAAGSSSELDFNLQTLEDKEIIVIKDTEKQDQSKMEGSVCLFKQAPFDPLIVLNWLLNDL CHOHOGS_1972_PE1 NOISO -------------------------------------------EASTDPIRVLSWLRRDL DIPORGS_3763_PE1 NOISO GAAGSRSEGDLNLENLEEKEIIVIKDTDKQDRSKXXXXXXXXXXXXXXXXXXXXXXXXXX DIPORGS_92_PE2 NOISO -------------------------------------------NESTDPVRVLSWLRRDL ECHTEGS_126_PE2 NOISO -------------------------------------------DAPTDPIRVLSWLRKDL ERIEUGS_141_PE2 NOISO -------------------------------------------EASTDPIRVLSWLRRDL GORGO12_5_PE11 NOISO -------------------------------------------DTSTDPVRVLSWLRRDL GORGOX_53_PE5 NOISO DAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDL HORSE6_34_PE8 NOISO -------------------------------------------DASTDPVRVLSWLRRDL HORSEX_41_PE23 ISOFORMIN DAGGSNSDGGLNLENLEEKEIIVIKDTEKQDQSKTEGSVCLFKQTPSDHICVFNWLLNDL HORSEX_41_PE24 ENSECAG00000024064 DAGGSNSDGGLNLENLEEKEIIVIKDTEKQDQSKTEGSVCLFKQTPSDHICVFNWLLNDL HS12_PE132 NOISO -------------------------------------------DTSTDPVRVLSWLRRDL HSX_PE989 ENSG00000147081 DAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDL HSX_PE990 ISOFORMIN DAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDL HSX_PE992 ISOFORMIN DAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDL HSX_PE994 ISOFORMIN DAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDL LOXAF15_51_PE10 NOISO -------------------------------------------EVPTDPVRVLSWLRRDL LOXAF56_1_PE2 NOISO CTIDRHTQNDILIYTFGDMLMLYIKKIHLLDKIRTEGSVCLFKQAPSDPISVLNWLLNDL MACEUGS_5645_PE1 NOISO XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXTEGSVCLFKQAPSDPISVLNWLLNDL MACMU11_5_PE11 NOISO -------------------------------------------DTSTDPVRVLSWLRRDL MACMUX_49_PE3 ENSMMUG00000023060 ------------------------------------------------------------ MACMUX_49_PE4 ISOFORMIN ------------------------------------------------------------ MICMUGS_1141_PE1 NOISO -------------------------------------------EAPVDPVRVLSWLRRDL MONDO8_118_PE12 ENSMODG00000018285 -------------------------------------------EASNDPVRVLSWLRKDL MONDO8_118_PE13 ISOFORMIN -------------------------------------------EASNDPVRVLSWLRKDL MONDO8_118_PE14 ISOFORMIN -------------------------------------------EASNDPVRVLSWLRKDL MONDOX_75_PE19 ENSMODG00000011265 ARGGPSSEGELDLESLEEKEIIVIKDTEKLDQSKTEGSVCLFKQAPSDPISVLNWLLNDL MONDOX_75_PE20 ISOFORMIN AR-GPSSEGELDLESLEEKEIIVIKDTEKLDQSKTEGSVCLFKQAPSDPISVLNWLLNDL MONDOX_75_PE21 ISOFORMIN ------------------------------------------SSTPSDPISVLNWLLNDL MONDOX_75_PE22 ISOFORMIN ----------------------------------TEGSVCLFKQAPSDPISVLNWLLNDL MOUSE6_PE2191 NOISO -------------------------------------------DTSTDPVRVLSWLRKDL MOUSEX_PE25 ENSMUSG00000050089 GAAGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDL MOUSEX_PE26 ISOFORMIN GAAGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDL MOUSEX_PE27 ISOFORMIN GAAGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDL MYOLUGS_84_PE2 NOISO -------------------------------------------EASTDPVRVLSWLRKDL ORNANULTRA315_PE1 ENSOANG00000013980 -------------------------------------------QAPSDAISVLNWLLNDL ORNANULTRA315_PE2 ISOFORMIN -------------LNIEDKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDAISVLNWLLNDL OTOGAGS_1660_1_PE8 NOISO -------------------------------------------EAPVDPVRVLSWLRRDL PANTR12_5_PE12 NOISO -------------------------------------------DTSTDPVRVLSWLRRDL PANTRX_50_PE18 NOISO DAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDL PIG5_63_PE6 NOISO ----------------------------------SDESLSIFKEASTDPIRVLSWLRRDL PIGX_44_PE24 NOISO DAAGSDSEGDLHLENLEEKEIIVIKDTEKQDQSKTEGSVCLFKQTPSDPISVLNWLLNDL PONPY12_5_PE10 NOISO -------------------------------------------DTSTDPVRVLSWLRRDL PONPYX_51_PE6 NOISO DAAGSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDL PROCAGS_115_PE2 NOISO -------------------------------------------EVPSDPVRVLSWLRRDL PTEVAGS_177_PE4 NOISO -------------------------------------------EASTDPVRVLSWLRKDL RABIT8_32_PE14 NOISO -------------------------------------------EVSKDPVRVLSWLRRDL RAT4_PE1735 NOISO -------------------------------------------DSSTDPVRVLSWLRKDL RATX_PE275 NOISO GAAGPRSEGELNLENLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDL SORARGS_3987_PE1 NOISO DVGCSRSDSELNLGDLEDKEIIVIKDTEKQDLSKTEGSVCLFKQAPSDPISVLNWLLNDL SPETRGS_89_PE2 NOISO -------------------------------------------EASTDPVRVLSWLRRDL TARSYGS_2113_PE1 NOISO -------------------------------------------DASTDPVRVLSWLRRDL TUPGBGS_81_PE2 NOISO ----------------------------------XXXXXXXXXXXXXXXX---------- TURTRGS_2687_PE3 NOISO DAAGSNSEGDLNLENLEEEEIIVIKDTEKQDSSKMERSVCLFKQAPSNPISVLYCLLSDL TURTRGS_791_PE4 NOISO ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX MATCH CONSENSUS ???????????????????????????????????????????????DP??VL?WL??DL

AILMEGL192563_1_1_PE3 NOISO QKYALGFQHALSPSA-FSCKHKVGDAEG---EYHELP-SGSCFSVYADQLNMDYMAN-GP AILMEGL192757_1_1_PE6 NOISO EKSTAGFQDVKFKPGESSLSGETS--------DLGDPRKGFSVDYYNTTNK------GSP ANOCA41_2_PE10 NOISO QKYAVGFQHALTPSG-SPCEHRRGKGNG---QYKPLP-SGSKEAGFADESSSDRGYKIQP ANOCA55_2_PE10 NOISO ------------------------------------------------------------ BOVIN5_115_PE4 NOISO EKSTAGFQDIRFKPGESSLGREMV--------SSGDPRKGFCVDYYNTTSR------GSP BOVINX_56_PE6 NOISO QKYALGFQHALSPSA-SSCKHKVGETEG---NCQKLS-SGNCYSIYANHLNMDCVNN-EP CALJA9_18_PE6 NOISO EKSTAEFQDVRFKPGESSFGGERS--------NSGDPHKGT--------TK------GTP CALJAX_49_PE37 ENSCJAG00000003006 QKYALGFQHALSPST-SNCKHKVEDTED---GYNRPS-SGNCYSVYTDQVNIDLL-N-RP CALJAX_49_PE38 ISOFORMIN QKYALGFQHALSPST-SNCKHKVEDTED---GYNRPS-SGNCYSVYTDQVNIDLL-N-RP CANFA27_45_PE5 NOISO EKSTAGFQDVRFKPGESSFNGEMS--------NLGDPRKGFSVNYYNSTTK------GSP CANFAX_44_PE4 NOISO QKYALGFQHALSPST-SSCKHKVGDTDG---EYHKIP-SGNCYSVYADQVNMDYMAN-GP CAVPO107_3_PE7 NOISO EKSTAEFQDAKFKPGESSFGEELA--------NPGDPRKGFSVDYYNNTTK------GSP CAVPO158_3_PE2 NOISO QKYALGFQHALSPST-SSCKHKVGDLDN---Y---NK-SGNCYSVYADKLSIDHMAK-GP CHOHOGS_1972_PE1 NOISO EQSTAGFQDTRFKPGESSLGGEMA--------NSGDSCKGFSVDYYNTTNR------GNP DIPORGS_3763_PE1 NOISO XXXXXXXXXXX-XXX-XXXXXXXXXXXX---XXXXXXXXXXXXXXXADQLNMDYIGN-GP DIPORGS_92_PE2 NOISO EKSTAGLQDLRFKPGESSLGEEPA--------SPADVRKGFSIDYYSTTAK------GSP ECHTEGS_126_PE2 NOISO EKSTAEFQDATFKPGEPPAGGEMT--------TSPDPRRGFSLDYYNTTNT------GQP ERIEUGS_141_PE2 NOISO EKSTAEFQDVRFKPGESPLSGESP--------SLVDPRMGFSVDYYNNTNR------GTP GORGO12_5_PE11 NOISO EKSTAEFQDVRFKPGE-SFGGETS--------NSADPHKGFSVDYYNTTTK------GTP GORGOX_53_PE5 NOISO QKYALGFQHALSPST-STCKHKVGDTEG---EYHRAS-SENCYSIYADQVNIDYLMN-RP HORSE6_34_PE8 NOISO ERSTAGFQDARFKAGESSLGGEMT--------ISGDPRKGFFVDYYNTTNK------GSP HORSEX_41_PE23 ISOFORMIN QKYALGFQHALSPSA-SSCKHKVGETEG---KFHKLP-SGNCYRVYADQLNMDYVTN-GP HORSEX_41_PE24 ENSECAG00000024064 QKYALGFQHALSPSA-SSCKHKVGETEG---KFHKLP-SGNCYRVYADQLNMDYVTN-GP HS12_PE132 NOISO EKSTAEFQDVRFKPGE-SFGGETS--------NSGDPHKGFSVDYYNTTTK------GTP HSX_PE989 ENSG00000147081 QKYALGFQHALSPST-STCKHKVGDTEG---EYHRAS-SENCYSVYADQVNIDYLMN-RP HSX_PE990 ISOFORMIN QKYALGFQHALSPST-STCKHKVGDTEG---EYHRAS-SENCYSVYADQVNIDYLMN-RP HSX_PE992 ISOFORMIN QKYALGFQHALSPST-STCKHKVGDTEG---EYHRAS-SENCYSVYADQVNIDYLMN-RP HSX_PE994 ISOFORMIN QKYALGFQHALSPST-STCKHKVGDTEG---EYHRAS-SENCYSVYADQVNIDYLMN-RP LOXAF15_51_PE10 NOISO EKSTAEFQDAEFKPGESSFGREIA--------NSGDPRKSFCVDYYNTTTK------GHP LOXAF56_1_PE2 NOISO QKYALGFQHALSPSA-SSCKHKVGDTEG---EYHKLP-YGNCYSVYADQLNMDYVGN-RP MACEUGS_5645_PE1 NOISO QKYALGFQHALSPSS-SSCKHKVGDLEG---GYRSP--QDNCYSVYADELSMDYVAN-NP MACMU11_5_PE11 NOISO EKSTAEFQDVRFKPGE-SFGGETS--------NSGDPHKGFSVDYYNT-TK------GTP MACMUX_49_PE3 ENSMMUG00000023060 ------------------------------------------------------------ MACMUX_49_PE4 ISOFORMIN ------------------------------------------------------------ MICMUGS_1141_PE1 NOISO EKSTAGFQDLRFKPGESSVGGETV--------NSGDPRKGFCVDYYNTTNK------GSP MONDO8_118_PE12 ENSMODG00000018285 EKCTSGFHDMKPSTGEMANRG--E--------HSGETRSGFTVDYYNNPGT---GGRSTP MONDO8_118_PE13 ISOFORMIN EKCTSGFHDMKPSTGEMANRG--E--------HSGETRSGFTVDYYNNPGT---GGRSTP MONDO8_118_PE14 ISOFORMIN EKCTSGFHDMKPSTGEMANRG--E--------HSGETRSGFTVDYYNNPGT---GGRSTP MONDOX_75_PE19 ENSMODG00000011265 QKYALGFQHALSPSS-SSCKHKVGDLEG---GYRSHPNKDNCYSVYADELSMDYMAN-NP MONDOX_75_PE20 ISOFORMIN QKYALGFQHALSPSS-SSCKHKVGDLEG---GYRSHPNKDNCYSVYADELSMDYMAN-NP MONDOX_75_PE21 ISOFORMIN QKYALGFQHALSPSS-SSCKHKVGDLEG---GYPK------------------------- MONDOX_75_PE22 ISOFORMIN QKYALGFQHALSPSS-SSCKHKVGDLEG---GYPK------------------------- MOUSE6_PE2191 NOISO EKSTAGFQDSRFKPGESSFVEEVA--------YPVDQRKGFCVDYYNTTNK------GSP MOUSEX_PE25 ENSMUSG00000050089 QKYALGFQHALSPSA-SSCKHKVGDLEG---DYSKIP-SENCYSVYADQVNFDYLNK-GP MOUSEX_PE26 ISOFORMIN QKYALGFQHALSPSA-SSCKHKVGDLEG---DYSKIP-SENCYSVYADQVNFDYLNK-GP MOUSEX_PE27 ISOFORMIN QKYALGFQHALSPSA-SSCKHKVGDLEG---DYSKIP-SENCYSVYADQVNFDYLNK-GP MYOLUGS_84_PE2 NOISO EKTTAGFQSVRFKPGESSPDGEMT--------NSEDPQKGFSVDYYNNTNK------DNA ORNANULTRA315_PE1 ENSOANG00000013980 QKYALGFQHALSPSA-SSCKHKVGDAVG-------------------------------P ORNANULTRA315_PE2 ISOFORMIN QKYALGFQHALSPSA-SSCKHKVGDAVGEGGHYSRSSHGGNCYSVYADELSVDL--N-RP OTOGAGS_1660_1_PE8 NOISO EKSTAGFQDVRFKPGESSLGGETT--------NLGDSHKGFSVDYYNTTNK------GSP PANTR12_5_PE12 NOISO EKSTAEFQDVRFKPGE-SFGGETS--------NSGDPHKGFCVDYYNTTTK------GTP PANTRX_50_PE18 NOISO QKYALGFQHALSPST-STCKHKVGDTEG---EYHRAS-SENCYSVYADQVNIDYLMN-RP PIG5_63_PE6 NOISO EKSTAGFQDVRFKPGESSFGGEMV--------NWTDPHKGFCVDYYNTTAK------GNP PIGX_44_PE24 NOISO QKYALGFQHALSPSA-SSCKHKVGDTEG---ECHQLH-SGNCYSVYADQLNMDYMAN-GP PONPY12_5_PE10 NOISO EKSTAEFQDVRFKPGE-SFGGETS--------NSGDPHKGFSVDYYNTTTK------GTP PONPYX_51_PE6 NOISO QKYALGFQHALSPST-STCKHKVGDTEG---EYHRAS-SENCYSVYADQVNIDYLMN-RP PROCAGS_115_PE2 NOISO EKSTAELQDAKFKPGESSFGKEMA--------NSGDPQKSFSVDYYNTTNK------GHP PTEVAGS_177_PE4 NOISO ERSTAGFQDVRFKPGESSLGGEMT--------SSGDQRKGFFVDYYNTTHE------GNP RABIT8_32_PE14 NOISO EKSTAGFQDVRFKPGESPFGEETT--------NIGDPHRGFSVDAYNTTNK------GSP RAT4_PE1735 NOISO EKSTAGFQDSRFKPGESSFGEEVA--------YPGDQRKGFCVDYYNTTNK------GNP RATX_PE275 NOISO QKYALGFQHALSPSA-SSCKHKVGDLEG---DYHKIP-SENCYSVYADQVNLDYLNK-GP SORARGS_3987_PE1 NOISO QKYALGFQHALSPSS-SSCKHRVGEMEQ---KCQNYP-SDNCYSVYADQLHTDYKTK-ES SPETRGS_89_PE2 NOISO EKSTAEFQDIRFKPGESSFGEETA--------NPG--NRGFCIDYFNNPQK------GSP TARSYGS_2113_PE1 NOISO EKSTAGFQDVRFQPRESSP-GETT--------NAEDPSKAFSVDYYNTTTK------GSP TUPGBGS_81_PE2 NOISO XXXXXXXXXXXXXXXXXXXXGDMT--------PSADPRKGFSVDYYNTTNR------GSP TURTRGS_2687_PE3 NOISO QKYALCFQQALSPSS-SSCRRQVGDTEG---KYHKLP-TGNCYRGYANQLKMDYVAK-GP TURTRGS_791_PE4 NOISO XXXXXXXXXX-------XXXXXXX--------XX---XXXXXXXXXXXXXX------XXX MATCH CONSENSUS ?K????FQ?????????????????????????????????????Y?????????????P

AILMEGL192563_1_1_PE3 NOISO QSLRLEMTAAKNTNNNQSPSTPPAKSPSTQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM AILMEGL192757_1_1_PE6 NOISO GRLHFEMTHRENP--IQGPSVQLG--------------NGSSVDEVSFYANRLTNLVIAM ANOCA41_2_PE10 NOISO TFVDNKRASVLFGCNSQAPANPLFHSPVGSKGLSPSEGSQKAADEVAGTVQKLCALVMQM ANOCA55_2_PE10 NOISO ------------------------------------------------------------ BOVIN5_115_PE4 NOISO GRLHFEMSHRENP--HQGPTC-----------------NGSSVDEVSFYANRLTNLVIAM BOVINX_56_PE6 NOISO QSLRLEMTAAKNTNNNQSPSTPPGKSPSNQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM CALJA9_18_PE6 NOISO GRLHFEITHKENP--FQGPRAQLG--------------NGNSVDEVSFYANRLTNLVIAM CALJAX_49_PE37 ENSCJAG00000003006 QNLQLEMAAAKNTNNNQSPS---AKSLSTQRAVISPDGK-CSLDDLSFYVDRLSFLVIQM CALJAX_49_PE38 ISOFORMIN QNLQLEMAAAKNTNNNQSPS---AKSLSTQRAVISPDGK-CSLDDLSFYVDRLSFLVIQM CANFA27_45_PE5 NOISO GRLHFEMSHRENP--VQGPSVQLG--------------NGSSVDEVSFYANRLTNLVIAM CANFAX_44_PE4 NOISO QSLRLEITAAKNTNNNQSPSTPPAKSPSSQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM CAVPO107_3_PE7 NOISO GRLHFEITHKESP--SQ-----AG--------------NKSSVDEVSFYANCITNLVIAM CAVPO158_3_PE2 NOISO QRLRLEMTAAKNTNNNQSPSTPVVKSSNTQREVKSPDGE-CSMDDLSYYVNRLSSLVIQM CHOHOGS_1972_PE1 NOISO GRFHFEVTHKENP--GQGSSARAG--------------NESSIDEVSFYANRLTNLVIAM DIPORGS_3763_PE1 NOISO QN-RLEMTAAK-TNNNQSPSNPANKS-SSQRTGNASEGE-CSMDDLSFYVNRLSSLVIQM DIPORGS_92_PE2 NOISO GRLHFEMTHKENP---QCPGTPLG--------------NSSSVDEVSFYANRLTNLVIAM ECHTEGS_126_PE2 NOISO GKLHFEVTHKETP--PTGP---TG--------------NERAVDEVSFYANRLTNLVTAM ERIEUGS_141_PE2 NOISO GRLHFEVSHKEKP--AQGLSTQIG--------------NGSSMDEVSFYANRLTNLVIAM GORGO12_5_PE11 NOISO ESLHFEMTHKEIP--CQGPRAQLG--------------NGSSVDEVSFYANRLTNLVIAM GORGOX_53_PE5 NOISO QNLHLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGE-CSIDDLSFYVNRLSSLVIQM HORSE6_34_PE8 NOISO GRLHFEMTHRDNP--SQGPSAQTG--------------NTSSVDEVSFYANRLTNLVIAM HORSEX_41_PE23 ISOFORMIN QSRHLEMTAAKNTNNNQSPSTPSPKSPNTQRAVISPGGE-CSVDDLSFYINRLASLVIQM HORSEX_41_PE24 ENSECAG00000024064 QSRHLEMTAAKNTNNNQSPSTPSPKSPNTQRAVISPGGE-CSVDDLSFYINRLASLVIQM HS12_PE132 NOISO ERLHFEMTHKEIP--CQGPRAQLG--------------NGSSVDEVSFYANRLTNLVIAM HSX_PE989 ENSG00000147081 QNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGE-CSIDDLSFYVNRLSSLVIQM HSX_PE990 ISOFORMIN QNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGE-CSIDDLSFYVNRLSSLVIQM HSX_PE992 ISOFORMIN QNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGE-CSIDDLSFYVNRLSSLVIQM HSX_PE994 ISOFORMIN QNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGE-CSIDDLSFYVNRLSSLVIQM LOXAF15_51_PE10 NOISO GRMHFEMTHKETP--PQGS---TG--------------NDRSVDEVSFYANRLTNLVIAM LOXAF56_1_PE2 NOISO QSLRLEMAAAKNTNNNQSPSTPPAKSPSTQRAVTSPDGE-CSMDDLSFYVNRLSSLVIQM MACEUGS_5645_PE1 NOISO HNLRLEMAAAKNTNNNQSPSSPPTKSPSTQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM MACMU11_5_PE11 NOISO ERLHFEMTHKENP--CQGPRAQLG--------------NGSSVDEVSFYANRLTNLVIAM MACMUX_49_PE3 ENSMMUG00000023060 ------------------------------------------------------------ MACMUX_49_PE4 ISOFORMIN ------------------------------------------------------------ MICMUGS_1141_PE1 NOISO GRLHFEITHKENP--CQGHRVPFG--------------GGSSVDEVSFYANRLTNLVIAM MONDO8_118_PE12 ENSMODG00000018285 GKLHLEMCHTENS--SRGSSAWTG------------GSNESTVDEVSFYANRLTNLVIAM MONDO8_118_PE13 ISOFORMIN GKLHLEMCHTENS--SRGSSAWTG------------GSNESTVDEVSFYANRLTNLVIAM MONDO8_118_PE14 ISOFORMIN GKLHLEMCHTENS--SRGSSAWTG------------GSNESTVDEVSFYANRLTNLVIAM MONDOX_75_PE19 ENSMODG00000011265 HNLRLEMAAAKNTNNNQSPSSPPAKSPSTQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM MONDOX_75_PE20 ISOFORMIN HNLRLEMAAAKNTNNNQSPSSPPAKSPSTQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM MONDOX_75_PE21 ISOFORMIN -----------NTNNNQSPSSPPAKSPSTQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM MONDOX_75_PE22 ISOFORMIN -----------NTNNNQSPSSPPAKSPSTQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM MOUSE6_PE2191 NOISO GRLHFEMSHKENP--SQGLISHVG--------------NGGSIDEVSFYANRLTNLVIAM MOUSEX_PE25 ENSMUSG00000050089 QNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPEGE-CSMDDLSFYVNRLSSLVIQM MOUSEX_PE26 ISOFORMIN QNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPEGE-CSMDDLSFYVNRLSSLVIQM MOUSEX_PE27 ISOFORMIN QNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPEGE-CSMDDLSFYVNRLSSLVIQM MYOLUGS_84_PE2 NOISO GRFHFEMTHKENP--LPGSGAQDD--------------NGSTVDEVSFYANRLTNLVIAM ORNANULTRA315_PE1 ENSOANG00000013980 YCRSYEMAAAKNTNNNQSPSSPSAKSPSFQRAHVNPEGE-CSMDDLSFYVNRLSSLVIQM ORNANULTRA315_PE2 ISOFORMIN YCRSYEMAAAKNTNNNQSPSSPSAKSPSFQRAHVNPEGE-CSMDDLSFYVNRLSSLVIQM OTOGAGS_1660_1_PE8 NOISO GRLHFEMTHRESP--PQGPRVQIG--------------AGSSVDEVSFYANRLTNLVIAM PANTR12_5_PE12 NOISO ERLHFEMTHKEIP--CQGPRAQLG--------------NRSSVDEVSFYANRLTNLVIAM PANTRX_50_PE18 NOISO QNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGE-CSIDDLSFYVNRLSSLVIQM PIG5_63_PE6 NOISO GRLHFEMTHRENP--SQGPSAQVG--------------NGSSVDEVSFYANRLTNLVIAM PIGX_44_PE24 NOISO QNLRLEMTASKNTNNNQSPSTPPAKSPSNQRAVISPDGE-CSMDDLSFYVNRLSSLVIQM PONPY12_5_PE10 NOISO ERLHFEMTHKENP--CQGPRAQLG--------------NGSSVDEVSFYANRLTNLVIAM PONPYX_51_PE6 NOISO QNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVTSPDGE-CSIDDLSFYVNRLSSLVIQM PROCAGS_115_PE2 NOISO GKLHFEITHKETP--PQGS---IG--------------NGCSVDDISFYANRLTNLVIAM PTEVAGS_177_PE4 NOISO GRLHFEMTHRENP--PQGPRAQLG--------------NGSSVDEVSFYANRLTNLVIAM RABIT8_32_PE14 NOISO GRFHFEITHKESP--AQGPGAVPG--------------NGRSVDEVSFYANRLTNLVIAM RAT4_PE1735 NOISO GRLHFEMSHKETP--PQGLIAHVG--------------NGGSIDEVSFYANRLTNLVIAM RATX_PE275 NOISO QNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPDGE-CSMDDLSYYVNRLSSLVIQM SORARGS_3987_PE1 NOISO HSLRLTETASKNTNNNQSPSSPPGKSPSNQKAVTSPDGE-CSMDDLSYYVNRLSSLVIQM SPETRGS_89_PE2 NOISO GRLHFEVTHKETP--SQDPCPQAG--------------KGSSVDEVSFYANRLTNLVIAM TARSYGS_2113_PE1 NOISO GRLHFKISHKENP--CQGPRAQIG--------------NKSSVDEVSFYANRLTNLVIAM TUPGBGS_81_PE2 NOISO GRLHFEMTHKENP--PQSPSALPG--------------HGSSVDEVSFYANRLTNLVIAM TURTRGS_2687_PE3 NOISO QGQHLEMTAAKNTNNNQSPFTPPAKSPSNQRTVISPDGE-CSTDDPSFYVSRLSPLVIQM TURTRGS_791_PE4 NOISO XXXXXXXXXXXXX--XXXXXXXXX--------------XXXXXXXXXXXXXXXTNLVIAM MATCH CONSENSUS ?????E??????????Q????????????????????????S?D??SFY?NRL??LVI?M

AILMEGL192563_1_1_PE3 NOISO ARKEIKEKLEG-GSKCLHHSLYPSPGN--KGKNSPRSAVSKIASEMAHDAVELTSAEM-- AILMEGL192757_1_1_PE6 NOISO ARKEINERIDGSEKKCVHQSLYMGD----EHT--PKKSLSMVASELVNETVSACSKNATS ANOCA41_2_PE10 NOISO ASKEISENLEDAASKCIRQAIYATK----DGKPLPPSSVSKVASEMVNKAMESAQEP--- ANOCA55_2_PE10 NOISO ------------------------------------------------------------ BOVIN5_115_PE4 NOISO ARKEINEKIDGSENRCVHQSVYMGD----EPP--PNKSLSKVASELVNETVTACSKNTPS BOVINX_56_PE6 NOISO ARKEIKEKLEN-GSKCLHHSIYPPSGD--KGKNSPRSAVSKIASEMAHDAVEVTSAEM-- CALJA9_18_PE6 NOISO ARKEINEAINGSEDKCVHQSLYIGN----EPI--PTKSLSKVASKLVNETVSACSRNAAP CALJAX_49_PE37 ENSCJAG00000003006 ARKEIMDKLEG-RSKCLHHSIVPSP------------TVSKIASEMAHEAMELTAAEL-- CALJAX_49_PE38 ISOFORMIN ARKEIMDKLEG-RSKCLHHSIVPSP------------TVSKIASEMAHEAMELTAAEL-- CANFA27_45_PE5 NOISO ARKEINERIDGSENRCIHQSLYMGD----EPT--PNKSLSKVASELVNETVSACSKNTTS CANFAX_44_PE4 NOISO ARKEIKEKLEG-GSKCLHHSIYPSPGD--KGKNSPRSPVSKIASEMAHDAVELTSAEM-- CAVPO107_3_PE7 NOISO ARKEIEKN-----DDTVQQSLYMGD----EPT--SQKSLSTVASELVNATVSACS----- CAVPO158_3_PE2 NOISO ARKEIKDKLEN-GSKCLHHSVYLPPGD--KGKSSPRSPLSKIASEMAHEAVELTSSEM-- CHOHOGS_1972_PE1 NOISO ARKEINEKIDGSENKCVHQSLYMGN----EPTP-PIKSLSKVASELVNETVSVCAKNAAP DIPORGS_3763_PE1 NOISO ARKEIKDKLEG-GNKCLHHSVFPPPGD--KGKISPRSAVSKIASEMAHEAVELTSAEM-- DIPORGS_92_PE2 NOISO ARKEINEKIDGSENKCVHQSLYLGE----EPA--PTKSLSTIASELVDDTVFACSKTVAP ECHTEGS_126_PE2 NOISO ARKEINEKIDGLENKCVHQSVYMGD----EPK--PNRSLSKVASELVNETVTACSTAAVS ERIEUGS_141_PE2 NOISO ARKEINEKIDGSENKCIHQSVYVGD----EPP--LNKSLSNVASELVNKTVTECSKSAAS GORGO12_5_PE11 NOISO ARKEINEKIDGSENKCVYQSLYMGN----EPT--PTKNLSKIASELVNETVSACSRNAAP GORGOX_53_PE5 NOISO AHKEIKKKLEG-KSKCLHHSICPSPEN--KERISPRTPASKIASEMAYEAVELTAAEM-- HORSE6_34_PE8 NOISO ARKEINETIDGSENKCIHQSLYMGD----DPT--PNKSLSAVASELVNKTVAACSKNGTS HORSEX_41_PE23 ISOFORMIN ARKEIKEKLEG-RNKCFHHSIYPPPGD--KGKNSPRSALSKIASEMVHDAVEVTSAEM-- HORSEX_41_PE24 ENSECAG00000024064 ARKEIKEKLEG-RNKCFHHSIYPPPGD--KGKNSPRSALSKIASEMVHDAVEVTSAEM-- HS12_PE132 NOISO ARKEINEKIDGSENKCVYQSLYMGN----EPT--PTKSLSKIASELVNETVSACSRNAAP HSX_PE989 ENSG00000147081 AHKEIKEKLEG-KSKCLHHSICPSPGN--KERISPRTPASKIASEMAYEAVELTAAEM-- HSX_PE990 ISOFORMIN AHKEIKEKLEG-KSKCLHHSICPSPGN--KERISPRTPASKIASEMAYEAVELTAAEM-- HSX_PE992 ISOFORMIN AHKEIKEKLEG-KSKCLHHSICPSPGN--KERISP------------------------- HSX_PE994 ISOFORMIN AHKEIKEKLEG-KSKCLHHSICPSPGN--KERISPRTPASKIASEMAYEAVELTAAEM-- LOXAF15_51_PE10 NOISO ARKEINEKIDGSENKCVHQSLYMGN----EPK--PNKSLSKVASDLVNETVTACSNNSVS LOXAF56_1_PE2 NOISO ARKEIKEKLEG-GSKCLHHSIYPQTGD--KGKNSPRSAVSKIASEMAHDAVEVTSAEM-- MACEUGS_5645_PE1 NOISO ARKEIKEKLEG-GSKCLHHSIYASAGD--KGKNSPRSAVSKIASEMAHDAVEVTSAEM-- MACMU11_5_PE11 NOISO ARKEINEKIDGSENKCVHQSLYMGN----EPP--PTKSLSKIASELVNETVSACSRNAAP MACMUX_49_PE3 ENSMMUG00000023060 ---------------------------------------------MAHEAVELTAAEM-- MACMUX_49_PE4 ISOFORMIN ---------------------------------------------MAHEAVELTAAEM-- MICMUGS_1141_PE1 NOISO ARKEINEKIDGSENKCVHQSLYMGD----EPP--PTKTLSKVASDLVSETVSACSKTAVS MONDO8_118_PE12 ENSMODG00000018285 ARKEINEKIDGSENKCIHQSVYMGE----EPP-SPNRTLSKVASELVNETVSLCAKE-TP MONDO8_118_PE13 ISOFORMIN ARKEINEKIDGSENKCIHQSVYMGE----EPP-SPNRTLSKVASELVNETVSLCAKE-TP MONDO8_118_PE14 ISOFORMIN ARKEINEKIDGSENKCIHQSVYMGE----EPP-SPNRTLSKVASELVNETVSLCAKE-TP MONDOX_75_PE19 ENSMODG00000011265 ARKEIKEKLEG-GSKCLHHSIYASTGD--KGKNSPRSAVSKIASEMAHDAVEVTSAEM-- MONDOX_75_PE20 ISOFORMIN ARKEIKEKLEG-GSKCLHHSIYASTGD--KGKNSPRSAVSKIASEMAHDAVEVTSAEM-- MONDOX_75_PE21 ISOFORMIN ARKEIKEKLEG-GSKCLHHSIYASTGD--KGKNSPRSAVSKIASEMAHDAVEVTSAEM-- MONDOX_75_PE22 ISOFORMIN ARKEIKEKLEG-GSKCLHHSIYASTGD--KGKNSPRSAVSKIASEMAHDAVEVTSAEM-- MOUSE6_PE2191 NOISO ARKEINEKIHGAENKCVHQSLYMGD----EPT--PHKSLSTVASELVNETVTACSKNISS MOUSEX_PE25 ENSMUSG00000050089 ARKEIKDKLEG-GSKCLHHSMYT-SGD--KGKTSPRSAVSKIASEMAHEAVELTSSEM-- MOUSEX_PE26 ISOFORMIN ARKEIKDKLEG-GSKCLHHSMYT-SGD--KGKTSPRSAVSKIASEMAHEAVELTSSEM-- MOUSEX_PE27 ISOFORMIN ARKEIKDKLEG-GSKCLHHSMYT-SGD--KGKTSPRSAVSKIASEMAHEAVELTSSEM-- MYOLUGS_84_PE2 NOISO ARKEINEKIDGSENKCVHQSVYMGD----EPP--PSKSLSKVASELVNETVSEYSKNTTS ORNANULTRA315_PE1 ENSOANG00000013980 ARKEIKEKLEG-GGKCLHQAIYASTSGERGNKNGPRSAVSKIASEMAHDAVEMTSAEI-- ORNANULTRA315_PE2 ISOFORMIN ARKEIKEKLEG-GGKCLHQAIYASTSGERGNKNGPRSAVSKIASEMAHDAVEMTSAEI-- OTOGAGS_1660_1_PE8 NOISO ARKEINEKIDGSENKCVHQSLYMGD----DPPPPPNKSLSKVASELVNETVTACSQNAAP PANTR12_5_PE12 NOISO ARKEINEKIDGSENKCVSQSLYMGN----EPT--PTKSLSKIASELVNETVSACSRNAAP PANTRX_50_PE18 NOISO AHKEIKEKLEG-KSKCLHHSICPSPGN--KERISPRTPASKIASEMAYEAVELTAAEM-- PIG5_63_PE6 NOISO ARKEINERIDGFEKKCVHQSVYLGE----EPA--PNKSLSKVASELVNETVSTCSNNATS PIGX_44_PE24 NOISO ARKEIKEKLEG-GSKCLHHSIYPPSGD--KGKDSPRSAVSKIASEMAHDAVEMTSAEM-- PONPY12_5_PE10 NOISO ARKEINEKIDGSENKCVYQSLYMGN----EPT--PTKSLSKIASELVNETVSACSRNAAP PONPYX_51_PE6 NOISO AHKEIKDKLEG-KSKCLHHSICPSPGN--KERISPRTAASKIASEMAHEAVELTAAEM-- PROCAGS_115_PE2 NOISO ARKEINEKIDGSENKCVHQSLYMGN----QPT--PKQSLSKVASDLVNETVAACSNNSAS PTEVAGS_177_PE4 NOISO ARKEINEKIDGSENKCVHQSLYMGD----EPT--LNKSLSKVASELVNETVSVCSKTPIS RABIT8_32_PE14 NOISO ARKEINEKIDGSEKKCIHQSLYMGD----EPA--PTKSLSKVASELVNETVSACSKNNDS RAT4_PE1735 NOISO ARKEINEKIHGTENKCVHQSLYMGD----DPT--PHKSLSTVASELVNETVSACSKNITG RATX_PE275 NOISO ARKEIKDKLEG-GNKCLHHSMYT-SGE--KGKTSPRSAVSKIASEMAHEAVELTSSEM-- SORARGS_3987_PE1 NOISO ARKEIKEKLEG-GGKCHHHSIFPQSGE--KGKTSPRSVLSKIASEMAHDAVEVTSAEI-- SPETRGS_89_PE2 NOISO ARKEINEKIDGSENKCVRQSLYVGD----EPV--PKKSLSTVASELVNETVSACANTTSP TARSYGS_2113_PE1 NOISO ARKEINETIDGSGNKCIHQSLYVGD----EPP--PNKSLSNMASELVNETVSACAGNAVP TUPGBGS_81_PE2 NOISO ARKEINEKIDGSENKCVHQSVYMGD----EPG--PNKTLSKVASELVNDTVSACSKNVNP TURTRGS_2687_PE3 NOISO ARKKIKEKLEG-GSKCLHHSIYPPSGD--KGKNSPRSAVSKITSEMAHDAVEVTSAER-- TURTRGS_791_PE4 NOISO AKE--IERIDGSESKCIHQSVYVGD----AAP----KKSSKVASELVNETVSACSRNSTS MATCH CONSENSUS ARKEI??K??G???KC?H?S??????????????P????SK?ASE?????V?????????

AILMEGL192563_1_1_PE3 NOISO ---QGTGE----------------------ECRE--------GGRKTFPYSELSNKN--- AILMEGL192757_1_1_PE6 NOISO DKPPGSGDRASGLLQSPPNLKYKTTLKIKESTKESKGPDDKPASKKSFFYKEVFESHNAG ANOCA41_2_PE10 NOISO --------------------------------NNMGKKDDGKGKKTSLFYGEVCSTKV-- ANOCA55_2_PE10 NOISO ------------------------------------------------------------ BOVIN5_115_PE4 NOISO DKAPGSGDRASGTLQSPPNLKYKSTLKIKESNKGGRGPDDRPSSKKSFFYKEVFESRNAG BOVINX_56_PE6 NOISO ---RGTGE----------------------ECRD--------GGRKTFLYSELSNKN--- CALJA9_18_PE6 NOISO DKAPSFGDRASESSQKPPNLKYKSILKMKESTRERQGPEDKPDSKKSFFYKEVFDSHNAD CALJAX_49_PE37 ENSCJAG00000003006 ---CGTEE----------------------ECKE--------GVQGSFLYNELCNKN--- CALJAX_49_PE38 ISOFORMIN ---CGTEE----------------------ECKE--------GVQGSFLYNELCNKN--- CANFA27_45_PE5 NOISO EKAPGSGDRASGLLQSPPNLKYKTTLKIKESTKKSKGPDDKPPSKKSFFYKEVFESRNAG CANFAX_44_PE4 NOISO ---RGTGE----------------------ECKE--------GGRKTFLYSELSNKN--- CAVPO107_3_PE7 NOISO -----------------PSMKYKSTLKIKE----SKSPGDKPASKKSVFYQELFESRNSG CAVPO158_3_PE2 NOISO ---RGTGE----------------------ENKE--------GGQKTFMYSELSNKS--- CHOHOGS_1972_PE1 NOISO DKAPGSGDRATRSSQNSPSIKYKSTLKFKECTREGKSPDDKPASRKSFFYKEVFESRNAG DIPORGS_3763_PE1 NOISO ---RGPGE----------------------EGRD--------CGRKTFLYSELSNKN--- DIPORGS_92_PE2 NOISO DKAPGSGDRALGSSRSPPNFKYKSTLKIKE----NKGPDDKPSSKKSFFYKEVFESRNAG ECHTEGS_126_PE2 NOISO DKAPGAGGRGE-ASRSPPTMRYKNTLKIKENTKGGKNLDDKPASRKSFFYKEVFECQNVG ERIEUGS_141_PE2 NOISO DKAPGSGDKASASPQSPPNLKYKSTLKIKESTKPNKCPDDRPSSKKSDFYKEEFESRNSG GORGO12_5_PE11 NOISO DKAPGSGDRVSGSSQSPPNLKYKSTVKIKESTQERQGPDDKPASKKSFFYKEVFESRNGD GORGOX_53_PE5 NOISO ---RGTGE----------------------ESRE--------GGQKSFLYSELSNKS--- HORSE6_34_PE8 NOISO DRVPGSGDRASGLLQSSPNLKYKTTLKIKESSKESKGPDDKPASKKSFFYKEVFESRNEG HORSEX_41_PE23 ISOFORMIN ---RGTGE----------------------DSRD--------GGRKTFMYSELSNKS--- HORSEX_41_PE24 ENSECAG00000024064 ---RGTGE----------------------DSRD--------GGRKTFMYSELSNKS--- HS12_PE132 NOISO DKAPGSGDRVSGSSQSPPNLKYKSTLKIKESTKERQGPDDKPPSKKSFFYKEVFESRNGD HSX_PE989 ENSG00000147081 ---RGTGE----------------------ESRE--------GGQKSFLYSELSNKS--- HSX_PE990 ISOFORMIN ---RGTGE----------------------ESRE--------GGQKSFLYSELSNKS--- HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN ---RGTGE----------------------ESRE--------GGQKSFLYSELSNKS--- LOXAF15_51_PE10 NOISO DKAPGSGDKALESSRSPPNVKYKSTLKIKESTKESKNPDDKPASRKSFFYKEVFESRNAG LOXAF56_1_PE2 NOISO ---RGTGE----------------------EGRE--------GGRKTFLYSELSNKN--- MACEUGS_5645_PE1 NOISO ---RGPGD----------------------LDH---------KDRKTFLYSELSNKS--- MACMU11_5_PE11 NOISO DKAPGSGDRASGSSQSPPNLKYKSTLKIEERAKERQGPEDKPASKKSFFYKEVFESRNGD MACMUX_49_PE3 ENSMMUG00000023060 ---RGTEE----------------------ESRE--------GGQKSFLYSELSNKS--- MACMUX_49_PE4 ISOFORMIN ---RGTEE----------------------ESRE--------GGQKSFLYSELSNKS--- MICMUGS_1141_PE1 NOISO DKAPGSGDRASG-----SNLKYKATLKMKESTKECKSPNDKPASKKSFFYKEVFEARNAG MONDO8_118_PE12 ENSMODG00000018285 DKAPGSGDRATPSSRSPPNVKYKSTLKFKETKE-CK---ADDKPKKSFFYKEVFESRNAG MONDO8_118_PE13 ISOFORMIN DKAPGSGDRATPSSR-------------------------NDKPKKSFFYKEVFESRNAG MONDO8_118_PE14 ISOFORMIN DKAPGSGDRATPSSRSPPNVKYKSTLKFKETKE-CK---ADDKPKKSFFYKEVFESRNAG MONDOX_75_PE19 ENSMODG00000011265 ---RSPGD----------------------LDH---------KDRKTFLYSELSNKS--- MONDOX_75_PE20 ISOFORMIN ---RSPGD----------------------LDH---------KDRKTFLYSELSNKS--- MONDOX_75_PE21 ISOFORMIN ---RSPGD----------------------LDH---------KDRKTFLYSELSNKS--- MONDOX_75_PE22 ISOFORMIN ---RSPGD----------------------LDH---------KDRKTFLYSELSNKS--- MOUSE6_PE2191 NOISO DKAPGSGDRASGSSQA-PGLRYTSTLKIKESTKEGKCPDDKPGTKKSFFYKEVFESRNAG MOUSEX_PE25 ENSMUSG00000050089 ---RGNGE----------------------DCRD---------GRKTFLYSEMCNKN--- MOUSEX_PE26 ISOFORMIN ---RGNGE----------------------DCRD---------GRKTFLYSEMCNKN--- MOUSEX_PE27 ISOFORMIN ---RGNGE----------------------DCRD---------GRKTFLYSEMCNKN--- MYOLUGS_84_PE2 NOISO DKVPGSGDRVFESLQSPSNLRYKTSLKINE----CKGPDGKPSSKKSFFYKEVFESHNAG ORNANULTRA315_PE1 ENSOANG00000013980 ---RGPGE----------------------QPGDEQPREEGGVPRKTFLYGEVSRKGG-- ORNANULTRA315_PE2 ISOFORMIN ---RGPGE----------------------QPGDEQPREEGGVPRKTFLYGEVSRKGG-- OTOGAGS_1660_1_PE8 NOISO DKVPGSGDRASG-----SNLKYKSTLKMKA----SKSPDDKPGSKKSFFFKEEFESRNAG PANTR12_5_PE12 NOISO DKAPGSGDRVSGSSQSPPNLKYKSALKIKESTKERQGPDDKPASKKSFFYKEVFESRNGD PANTRX_50_PE18 NOISO ---RGTGE----------------------ESRE--------GGQKSFLYSELSNKS--- PIG5_63_PE6 NOISO DKTPGSGDRASGSSQNAPNLKYKSTLKIKESTKGSRGPDDRPASKKSFFYKEVFESRNAG PIGX_44_PE24 NOISO ---RGTGE----------------------ECRE--------GGRKTFLYSELSNKN--- PONPY12_5_PE10 NOISO DKAPGSGDRVSGSSQSPPNLKYKSTLKIKESTKERQSPDDKPASKKSFFYKEVFESRNGD PONPYX_51_PE6 NOISO ---RGTGG----------------------KS---------------------------- PROCAGS_115_PE2 NOISO DKPPGSGDKALQSSQSPPSIKYKSTLKIKENTKEGKSPDDRPNSRKSFFYKEVFESRNSG PTEVAGS_177_PE4 NOISO DKVPGSGDRTSRSLQSPPSLKYKTTLKFKESTKESKSPADRPASKKSFFYKEVFESRNAG RABIT8_32_PE14 NOISO DKAPGSGDRASGSS-NIPNLKKKSTLKIKESTVESKGAEDKPVSRKSFFYKEVFESRNAG RAT4_PE1735 NOISO DKAPGSGDRALASSQS-PGLRFTSTLKIKESTKEGKCPDNKPGSKKSFFYKEVFESRNAG RATX_PE275 NOISO ---RGNGE----------------------EGRD---------GRKTFLYSELSNKN--- SORARGS_3987_PE1 NOISO ---RGNGE----------------------ECKE--------GGRKSFLYSELANKN--- SPETRGS_89_PE2 NOISO DKAPGSGDRASGLSQSPPNLKYKSTLKIKECTKESKCPDDKSASKKSFFYKEVFESRNAG TARSYGS_2113_PE1 NOISO DKAPRSGDRASGSLQSLRNLKYKSTVKIKESNKGSQGP-----SRKSFFFKEVLESRNAG TUPGBGS_81_PE2 NOISO EKAPGSGDRASASSRSPPNLKYKSTLKIKESTKESKGPDDKPASKKSFFYKEVFESRNAG TURTRGS_2687_PE3 NOISO ---QGTGE----------------------ECRE--------GGRKTFLYSELSNKS--- TURTRGS_791_PE4 NOISO DKAPGSYDRASGTSQSPVNVKYKSALKIKDSTKESRGPDDKPSSKKSFFYKEVFESCNAS MATCH CONSENSUS ????G?G??????????????????????????????????????K?F?Y?E????????

AILMEGL192563_1_1_PE3 NOISO --KGGDK-------QM----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS AILMEGL192757_1_1_PE6 NOISO DAKEGGR-SLPGERRMFRG--QERPDDFTASVSQGIMTYANSVVSDMMVSIMKTLRIQVK ANOCA41_2_PE10 NOISO -NLCR--------KMI----PRQSGRPDTSSFNKGLMVYANKNAKDMTFSFVNATKVHKR ANOCA55_2_PE10 NOISO --------------------------EYTNSLSKGILVYANSVVSDMMVSVMKTMKVKVN BOVIN5_115_PE4 NOISO DAKEGGR-TLPAERKMFRG--YERPDDFTASISQGIMTYANSVVSDMMVSIMKTLKIQVK BOVINX_56_PE6 NOISO --KGGDK-------QM----CQRDSKDFADSISKGLMVYANQVASDMMVSVMKTLKVHSS CALJA9_18_PE6 NOISO YARAGGR-FFPWERKMFRG--QERADDFTTSVSERIMTYANSVVSDIMVSIMKTLRIQVK CALJAX_49_PE37 ENSCJAG00000003006 --KSGDK-------QI----CQRDSQEFADSISKGFMVYANQVATDMMFSTMKTLKVHSS CALJAX_49_PE38 ISOFORMIN --KSGDK-------QI----CQRDSQEFADSISKGFMVYANQVATDMMFSTMKTLKVHSS CANFA27_45_PE5 NOISO DAKEGGR-SLPGERKVFRG--QERPDDFTASVSQGIMTYANSVVSDMMVSIMKTLRIQVK CANFAX_44_PE4 NOISO --KSGDK-------QM----CQRDSKEFADCISKGLMVYANQVASDMMVSVMKTLKIHSS CAVPO107_3_PE7 NOISO GAKEGGR-SLPAEKKMSKG--KERADDFTGSVSQGIMTYANSVVSDMMVSIMKTLKIQVK CAVPO158_3_PE2 NOISO --KCGEK-------QM----FQKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS CHOHOGS_1972_PE1 NOISO DATEGGR-VLPGERKMFRG--QERPDDFTASISQGIMTYANSVVSDMMISIMKTLRIQVK DIPORGS_3763_PE1 NOISO --KGGEK-------QM----CPRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSC DIPORGS_92_PE2 NOISO DAREGGR-ALPGDRKIFSG--RDRPDDFTASVSQGIMTYANSVVSDMMVSIMKTLRIQVK ECHTEGS_126_PE2 NOISO DAKEGGR-PLPGERKMFRG--SERTNDFTNSVSQGIMTYANSVVSDMMVSIMKTLKIQVK ERIEUGS_141_PE2 NOISO DAREGGKSFLPGERKLFRG--QERPDDFTTSVSQGIMTYANSVVSDMMVSIMKTLKIQVK GORGO12_5_PE11 NOISO YAREGGR-FFPRERKRFRG--QERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKIQVK GORGOX_53_PE5 NOISO --KSGDK-------QM----SQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSS HORSE6_34_PE8 NOISO DTKEGGR-SLPAERKMFRG--QERPDDFTASVSQGIMTYANSVVSDMMVSIMKTLRIQVK HORSEX_41_PE23 ISOFORMIN --KSGDK-------QM----FQRDSKEFADSISKGLMVYANQVASDMMFSVMKTLKVHSS HORSEX_41_PE24 ENSECAG00000024064 --KSGDK-------QM----FQRDSKEFADSISKGLMVYANQVASDMMFSVMKTLKVHSS HS12_PE132 NOISO YAREGGR-FFPRERKRFRG--QERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKIQVK HSX_PE989 ENSG00000147081 --KSGDK-------QM----SQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSS HSX_PE990 ISOFORMIN --KSGDK-------QM----SQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSS HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN --KSGDK-------QM----SQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSS LOXAF15_51_PE10 NOISO DAKESGR-SLPGERKMFRG--VERPDDFTASVSQGIMTYANSVVSDMMVSIMKTLRIQVK LOXAF56_1_PE2 NOISO --KGGDK-------QM----CQKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MACEUGS_5645_PE1 NOISO --KGG-D------KQM----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MACMU11_5_PE11 NOISO YARESGR-FFPRERKRFRG--QERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKIQVK MACMUX_49_PE3 ENSMMUG00000023060 --KSGDK-------QM----SQRESKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MACMUX_49_PE4 ISOFORMIN --KSGDK-------QM----SQRESKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MICMUGS_1141_PE1 NOISO DAREGRK-FIPGERKMFQG--QERPDDFTASISEGIMTYANSVVSDMMVSIMKTLRIQVK MONDO8_118_PE12 ENSMODG00000018285 D---GGR-------KVFGA--EPRRDDFTASVSQGIMTYANSVVSDMMVSIMKTLKIQVK MONDO8_118_PE13 ISOFORMIN D---GGR-------KVFGA--EPRRDDFTASVSQGIMTYANSVVSDMMVSIMKTLKIQVK MONDO8_118_PE14 ISOFORMIN D---GGR-------KVFGA--EPRRDDFTASVSQGIMTYANSVVSDMMVSIMKTLKIQVK MONDOX_75_PE19 ENSMODG00000011265 --KGGSD------KQM----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MONDOX_75_PE20 ISOFORMIN --KGGSD------KQM----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MONDOX_75_PE21 ISOFORMIN --KGGSD------KQM----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MONDOX_75_PE22 ISOFORMIN --KGGSD------KQM----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS MOUSE6_PE2191 NOISO DAKEGGR-SLPGDQKLFRTSPDNRPDDFSNSISQGIMTYANSVVSDMMVSIMKTLKIQVK MOUSEX_PE25 ENSMUSG00000050089 --KCGEK------QQM----CPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSC MOUSEX_PE26 ISOFORMIN --KCGEK------QQM----CPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSC MOUSEX_PE27 ISOFORMIN --KCGEK------QQM----CPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSC MYOLUGS_84_PE2 NOISO DSKEGAR-SLPGERKMFKG--QERPDDFTTSVSQKIMTYANSVVSDMMVSIMKTLKIQVK ORNANULTRA315_PE1 ENSOANG00000013980 -PKGGDK-------QM----CQSGSKDFADSISKGIMVYANQVASDMMLSVMKTLRVQSS ORNANULTRA315_PE2 ISOFORMIN -PKGGDK-------QM----CQSGSKDFADSISKGIMVYANQVASDMMLSVMKTLRVQSS OTOGAGS_1660_1_PE8 NOISO DAREGKK-FLPGERKMFQG--QERTDDFTTSVSEGIMTYANSVVSDMMVSIMKTLRIQVK PANTR12_5_PE12 NOISO YAREGGR-FFPWERKRFRG--QERPDDFTASVSEGIMSYANSVVSDMMVSIMKTLKIQVK PANTRX_50_PE18 NOISO --KSGDK-------QM----SQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSS PIG5_63_PE6 NOISO DATEGGR-SLPAERKMFRG--QERPDDFTTCVSQGIMTYANSVVSDMMVSIMKTLKIQVK PIGX_44_PE24 NOISO --KGGDK-------QV----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSS PONPY12_5_PE10 NOISO YAREGGR-FFPRERKRFRG--QERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKIQVK PONPYX_51_PE6 NOISO ------------------------------------------------------------ PROCAGS_115_PE2 NOISO DARADRR-CLPEERKIFRG--LERPDDFTSSVSQGIMTYANSVVSDMMVSIMKTLRIQVK PTEVAGS_177_PE4 NOISO DAKEGGK-FLPGERKIFRG--QERPNDFTASVSQGIMTYANSVVSDMMVSIMKTLKVQVK RABIT8_32_PE14 NOISO DAREGGR--LPGERKLFRG--QERPDDFTTSISQGIMTYANSVVSDMMVSIMKTLRIQVK RAT4_PE1735 NOISO DAKEGGR-SLPGDRKLFRCP--DRPDDFSNSISQGIMTYANSVVSDMMVSIMKTLKIQVK RATX_PE275 NOISO --KCGEK------QQM----CPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSC SORARGS_3987_PE1 NOISO --KGGDK-------QM----CQRDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVQSS SPETRGS_89_PE2 NOISO DAKEGGK-SLPGEKKMFSG--QERPSDFTASVSQGIMTYANSVVSDMMVSIMKTLRIQVK TARSYGS_2113_PE1 NOISO DTREGGR-------RLFRG--QERPDDFTAPVSDGIMMYANSVVSDMMASIMRTLRIQVK TUPGBGS_81_PE2 NOISO DAREGGR-SLPGERRKFGG--QERPDDFTSSVSQGIMTYANSVVSDMMVSIMKTLRIQVK TURTRGS_2687_PE3 NOISO --KGGDK-------YM----CQRDNKEFADSISKMFMVYANQVASDTMFSVMQNLKVHSS TURTRGS_791_PE4 NOISO DATEGRR-SLPAEGEMLRE--QEKPNDFTASVSQGIITYANSVVSDMMVSIMKTLKIQVK MATCH CONSENSUS ????G??????????????????????F??S?S?G?M?YAN?V?SDMMVS?MKTL?????

AILMEGL192563_1_1_PE3 NOISO RK-PIPACVVLKRVLLNHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK AILMEGL192757_1_1_PE6 NOISO D--TTIATILLKKVLLKHAKEVVSDLIDSFMKNLHNVTGTLMTDSDFVSAVKRSLFSHGS ANOCA41_2_PE10 NOISO --APLPACVVLKRVFLKHTKDVISDLIDSTMKNLHNVTGVLMTDSDFVTTVKKNLFHAGT ANOCA55_2_PE10 NOISO D--SNIACAVLKKVLLKHSKEVVSDLIDSCMKNLHDVTGTLMTDSDFVSAVKRSLFTQGS BOVIN5_115_PE4 NOISO D--TTIATIVLKKVLIKHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSFFSHGS BOVINX_56_PE6 NOISO GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK CALJA9_18_PE6 NOISO D--TTIATILLKKVLLKHAKDVVSDLIDSFMMNLHNVTGTLMTNTDFVSAVKRTVFSHGS CALJAX_49_PE37 ENSCJAG00000003006 GK-PIPACVILKRVLLKHTKEIVSDLIDSCMKNLHTITGVLMTDSDFVSAVKRNLFNYGK CALJAX_49_PE38 ISOFORMIN GK-PIPACVILKRVLLKHTKEIVSDLIDSCMKNLHTITGVLMTDSDFVSAVKRNLFNYGK CANFA27_45_PE5 NOISO D--TTIATILLKKVLLKHAKEVVSDLIDSFMKNLHNVTGTLMTDSDFVSAVKRSLFSHGS CANFAX_44_PE4 NOISO GK-PIPACVVLKRVLLKHTKEIVSDLIDSCLKNLHNITGVLMTDSDFVSAVKRNLFNHGK CAVPO107_3_PE7 NOISO D--STIASILLKRVLIKHAKEVVSDLIDSFMTNLHNVTGTLMTDSDFLCAVKRSLFSQGS CAVPO158_3_PE2 NOISO GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK CHOHOGS_1972_PE1 NOISO D--STIATILLKKVLIKHAKEVVSDLIDSLMKNLHNVTGTLMSDTDFVSAVKRSLFSHGS DIPORGS_3763_PE1 NOISO GK-PIPACVVLKRVLLKHTKDIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK DIPORGS_92_PE2 NOISO D--TTIATILLKQVLIKHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSLFSQGS ECHTEGS_126_PE2 NOISO D--TTIATVLLKKVLIRHAKEVVSDLIDSFMRNLHNVTGTLMTDTDFVSAMKRGLFSHSS ERIEUGS_141_PE2 NOISO D--TTIATILLKKVLIKHAKDVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSLFSHGS GORGO12_5_PE11 NOISO D--TTIATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSHGS GORGOX_53_PE5 NOISO GK-PIPACVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK HORSE6_34_PE8 NOISO D--TTIITILLKKVLIKHAKKVVSDLIDSFMKNLHSVTGTLMTDSDFVSAVKRSLFSQGS HORSEX_41_PE23 ISOFORMIN GK-PIPACAVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK HORSEX_41_PE24 ENSECAG00000024064 GK-PIPACAVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK HS12_PE132 NOISO D--TTIATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSHGS HSX_PE989 ENSG00000147081 GK-PIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK HSX_PE990 ISOFORMIN GK-PIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN GK-PIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK LOXAF15_51_PE10 NOISO D--TTIATILLKKVLIRHAKEVVSDLIDSFMRNLHNVTGTLMTDTDFVSAVKRSLFSHGS LOXAF56_1_PE2 NOISO GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MACEUGS_5645_PE1 NOISO GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MACMU11_5_PE11 NOISO D--TTLATILLKKVLLKHAKDVVSDLIDSFMRNLHSITGTLMTDTQFVSAVKRTVFTHGS MACMUX_49_PE3 ENSMMUG00000023060 GK-PIPACVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK MACMUX_49_PE4 ISOFORMIN GK-PIPACVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK MICMUGS_1141_PE1 NOISO D--TTIATILLKKVLLKHAKDVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSFFCHGS MONDO8_118_PE12 ENSMODG00000018285 D--TTIATILLKKVLMRHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSLFSHGS MONDO8_118_PE13 ISOFORMIN D--TTIATILLKKVLMRHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSLFSHGS MONDO8_118_PE14 ISOFORMIN D--TTIATILLKKVLMRHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSLFSHGS MONDOX_75_PE19 ENSMODG00000011265 GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MONDOX_75_PE20 ISOFORMIN GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MONDOX_75_PE21 ISOFORMIN GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MONDOX_75_PE22 ISOFORMIN GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MOUSE6_PE2191 NOISO D--TTIATILLKKVLMKHAKEVVSDLIDSFMKNLHGVTGSLMTDTDFVSAVKRSFFSHGS MOUSEX_PE25 ENSMUSG00000050089 GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MOUSEX_PE26 ISOFORMIN GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MOUSEX_PE27 ISOFORMIN GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK MYOLUGS_84_PE2 NOISO D--TTIATILLKKVLLGHAKEVVSDLIDSLMKNLHNVTGTLMTDTDFVSAVKRSLFFHGS ORNANULTRA315_PE1 ENSOANG00000013980 GKSPIPACVVLKKVLLKHTKDIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFKQGK ORNANULTRA315_PE2 ISOFORMIN GKSPIPACVVLKKVLLKHTKDIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFKQGK OTOGAGS_1660_1_PE8 NOISO D--TTIATILLKKVLLKHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSVFSHGS PANTR12_5_PE12 NOISO D--TTIATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSHGS PANTRX_50_PE18 NOISO GK-PIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK PIG5_63_PE6 NOISO D--TTIATILLKKVLIRHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSLFSHGS PIGX_44_PE24 NOISO GK-PIPACMVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK PONPY12_5_PE10 NOISO D--TTIATILLKKVLLKHAKEVVSDLIDSFMRNLHSVTGTLMTDTQFVSAVKRTVFSHGS PONPYX_51_PE6 NOISO ----IP-AEVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWK PROCAGS_115_PE2 NOISO D--TTIATILLKQVLLKHAKDVVSDLIDSLMRNLHSVTGTLMTDTDFISAVKRSLFSHGR PTEVAGS_177_PE4 NOISO D--TTIATILLKKVLIKHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSFFGHGS RABIT8_32_PE14 NOISO D--TTIATILLKKVLIKHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSFFSHGS RAT4_PE1735 NOISO D--TTIATILLKKVLMKHAKEVVSDLIDSFMKNLHSVTGSLMTDTDFVSAVKRSFFSHGS RATX_PE275 NOISO GK-PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK SORARGS_3987_PE1 NOISO GK-PIPACVVLKKVLLKHTKDVVSDLINSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGK SPETRGS_89_PE2 NOISO D--TTIATILLKKVLIKHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFISAVKRSLFSQGS TARSYGS_2113_PE1 NOISO D--TTIITIVLKKVLLKHTKEVVSDLIDSFMKNLHSATGTLMTDEDFVSAVKRNVFSHGS TUPGBGS_81_PE2 NOISO D--TTIATILLKKVLIKHAKEVVSDLIDSFMKNLHNVTGTLMTDTDFVSAVKRSLFSHGS TURTRGS_2687_PE3 NOISO GK-PIPACVVVRRVLLKHTKEIVSDLIDSCVKNLRNITGVLMANSDFFSTVRRNLFNHGK TURTRGS_791_PE4 NOISO D--TTIATILLKKVLIKHAEEVVSDLIDSFMKNLHDVTGALMTDTDFVSAVKRSLFVHGS MATCH CONSENSUS ??????A???LK?VL??H?KE?VSDLIDS?MKNLH??TG?LMTD?DFVSAVKR??F??G?

AILMEGL192563_1_1_PE3 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLSYASLKAGSHDPKCKNH-SLEFS AILMEGL192757_1_1_PE6 NOISO QKATDIMDAMLGKLYTVMFAKKPPENIRKTKDKSESYSLVSMKG-MGDPKNQ---NVNFA ANOCA41_2_PE10 NOISO QKSTEILEAMVLRMYNALMTETKE--------RGHSLVYSLLKTGCSLDA--NSPNMHFA ANOCA55_2_PE10 NOISO QKASEIVQAMLNRLHNALIVQKQVNEKAK--SQRMTFATVKTAA-GCDAKTQ---NMRFS BOVIN5_115_PE4 NOISO QKATDIMDAMLGKLYSVIFAKKPPETVRKTKDKSESYSLVSMKG-MGDPKHR---NVNFA BOVINX_56_PE6 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKSQCLSYTSLKAGSHDAKCKNQ-SLEFS CALJA9_18_PE6 NOISO QKASDIMDAMLGNLYNVMFADKVSEHIRKAKDKAERYSLLSMKG-MGDPKKR---NVNFA CALJAX_49_PE37 ENSCJAG00000003006 QNAAAIMEAMLRRLVSALIGEKKE-------TKSQSLSYATLKAGSYDPKYDNQ-SLELS CALJAX_49_PE38 ISOFORMIN QNAAAIMEAMLRRLVSALIGEKKE-------TKSQSLSYATLKAGSYDPKYDNQ-SLELS CANFA27_45_PE5 NOISO QKATDIMDAMLGKLYTVMFAKKPPENLRKTKDKSESYSLVSMKG-MCDPKNQ---NTNFA CANFAX_44_PE4 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKCQSLSYASLKAGSHDPKCKNQ-SLEFS CAVPO107_3_PE7 NOISO QKATDIMDAMLGKLYNMMFANKYPETIRRAKDKSESYSLISMKG-MGDPKYR---NMNFL CAVPO158_3_PE2 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLSYASLKAGSQDPKCKNQ-SLEFS CHOHOGS_1972_PE1 NOISO QKALNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX-XXXXXXX---XXXXX DIPORGS_3763_PE1 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYATLKAGTNDPKCKNQ-SLEFS DIPORGS_92_PE2 NOISO QKATDIMDAMMGKLYNVIFSKKFPEGTRKTKDKCESFSMVSMKG-RGDPKGR---NMNF- ECHTEGS_126_PE2 NOISO QTATDIMDAMLSQLYNVIFPQKAPEPT----KIQECYSLFSMKG-MGDPR-----PFIFP ERIEUGS_141_PE2 NOISO QKATDIMDAMMGKLYTVIFSKKSPGAIRRTQGMSECYSLIS-KG-MGGPKSR---NVNFA GORGO12_5_PE11 NOISO QKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMKG-MGDPKNR---NVNFA GORGOX_53_PE5 NOISO QNATDITEAMLKRLVSALIGEEKE-------TKSQSLSYASLKAGSHDPKCRNQ-SLEFS HORSE6_34_PE8 NOISO QKATDIMDAMLGKLYTVIFTKRPPENIRKTKDKAESFSLVSMKG-MGDPKNR---NVNFA HORSEX_41_PE23 ISOFORMIN QNAADIMEAMLKRLVGALLGEKKE-------TKSQSVSYASLKAGSQDPKCKNQ-SLEFS HORSEX_41_PE24 ENSECAG00000024064 QNAADIMEAMLKRLVGALLGEKKE-------TKSQSVSYASLKAGSQDPKCKNQ-SLEFS HS12_PE132 NOISO QKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMKG-MGDPKNR---NVNFA HSX_PE989 ENSG00000147081 QNATDIMEAMLKRLVSALIGEEKE-------TKSQSLSYASLKAGSHDPKCRNQ-SLEFS HSX_PE990 ISOFORMIN QNATDIMEAMLKRLVSALIGEEKE-------TKSQSLSYASLKAGSHDPKCRNQ-SLEFS HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN QNATDIMEAMLKRLVSALIGEEKE-------TKSQSLSYASLKAGSHDPKCRNQ-SLEFS LOXAF15_51_PE10 NOISO QKATDIMDAMMGKLYTVMFAKKVPENVRKSKDKAESYSLVSMKG-MGDPKHR---NVNFA LOXAF56_1_PE2 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLSYASLKAGSHDPKCKNQ-SLEFS MACEUGS_5645_PE1 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYASLKAGSHDAKNKNQ-SLEFS MACMU11_5_PE11 NOISO QKAADIMDAMLRKLYNVMFVKKVPEHVRKAQDTAESYSLISMKG-MGDPKHR---NVNFA MACMUX_49_PE3 ENSMMUG00000023060 QNAADIMEAMLKRLVSALIGEEKE-------TKSQSLSYASLKAGSHDPKCRNQ-SLEFS MACMUX_49_PE4 ISOFORMIN QNAADIMEAMLKRLVSALIGEEKE-------TKSQSLSYASLKAGSHDPKCRNQ-SLEFS MICMUGS_1141_PE1 NOISO QKATDIMDAMLNKLYNVMFAKKVPEIIRKSKDKSESYSLISMKG-IGDPKHR---NMNFA MONDO8_118_PE12 ENSMODG00000018285 QKATDIMDAMLGKLHSVMLKKSNEPCKKPCKDKSESLSLVSMKGGMNDPRHR---GMNYS MONDO8_118_PE13 ISOFORMIN QKATDIMDAMLGKLHSVMLKKSNEPCKKPCKDKSESLSLVSMKGGMNDPRHR---GMNYS MONDO8_118_PE14 ISOFORMIN QKATDIMDAMLGKLHSVMLKKSNEPCKKPCKDKSESLSLVSMKGGMNDPRHR---GMNYS MONDOX_75_PE19 ENSMODG00000011265 QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYASLKAGTHDCKNKNQTGLEFS MONDOX_75_PE20 ISOFORMIN QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYASLKAGTHDCKNKNQTGLEFS MONDOX_75_PE21 ISOFORMIN QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYASLKAGTHDCKNKNQTGLEFS MONDOX_75_PE22 ISOFORMIN QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYASLKAGTHDCKNKNQTGLEFS MOUSE6_PE2191 NOISO QKATDIMDAMLGKLYNVMFAKKFPENIRRARDKSESYSLISTKSRAGDPKLS---NLNFA MOUSEX_PE25 ENSMUSG00000050089 QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYATLKAGTNDPKCKNQ-SLEFS MOUSEX_PE26 ISOFORMIN QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYATLKAGTNDPKCKNQ-SLEFS MOUSEX_PE27 ISOFORMIN QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYATLKAGTNDPKCKNQ-SLEFS MYOLUGS_84_PE2 NOISO QKASDIMDAMLWKLYSVMFAKKPPENIRKTKDKSESYSVVSMKG-MGGPKNQ---KVNFA ORNANULTRA315_PE1 ENSOANG00000013980 QNAADIMEAMLKRLVSALLGEKKD------QSKSGSLAYASLKAGSHDSRSKNQ-SLDYT ORNANULTRA315_PE2 ISOFORMIN QNAADIMEAMLKRLVSALLGEKKD------QSKSGSLAYASLKAGSHDSRSKNQ-SLDYT OTOGAGS_1660_1_PE8 NOISO QKATDIMDAMLGKLYNVIFAKKIPETIRKSKDKCESYSLVSMKG-LGDPKNR---NVNFT PANTR12_5_PE12 NOISO QKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMKG-MGDPKNR---NVNFA PANTRX_50_PE18 NOISO QNATDITEAMLKRLVSALIGEEKE-------TKSQSPSYASLKAGSHDP----------- PIG5_63_PE6 NOISO QKATDIMDAMLGKLYTVVFAKKPPDTGSRAKDKSERYSLVSVKE-MGDPKNR---NINFA PIGX_44_PE24 NOISO QNAADIMEAMLKRLVSALLGEKRE-------TKSQSLSYASLKAGSHDPKCKNQ-SLEFS PONPY12_5_PE10 NOISO QKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMKG-MGDPKNR---NVNFA PONPYX_51_PE6 NOISO QNATDIMEAMLKRLVSALIGEEKE-------TKSQSLSYASLKAGSHDPKCRNQ-SLEFS PROCAGS_115_PE2 NOISO QKATDIMDAMMAKLYNVIFVKKVPENVRRSKDKAENYSLISMKG-MNDPKHR---NVNFA PTEVAGS_177_PE4 NOISO QKATDIMDAMLSKLYNVMFTKKFPENIRKTKDQSEIYSVVSMKG-MGDPKNR---NVNFA RABIT8_32_PE14 NOISO QKATDIMDAMLGKLYTVMFTKKFPENLRKTKDKQESYSLMSMKG-MGDPRNR---NVNFA RAT4_PE1735 NOISO QKATDIMDAMLGKLYNVMCAKKYPENIRKARDKSESYSLISMKSRPGDPKLS---NLNFA RATX_PE275 NOISO QNAADIMEAMLKRLVSALLGEKKE-------TKSQSLAYATLKAGTHDPKCKNQ-SLEFS SORARGS_3987_PE1 NOISO QNAADIMEAMLKRLVSALLGEKRE-------TKSQCLSYASLKAGSQDPKCKNQ-SLEFS SPETRGS_89_PE2 NOISO QKATDIMDAMLGKLYTVMFAKKFPDNLRKTKDKSESYSLLSMKG-ID----R---NMNFT TARSYGS_2113_PE1 NOISO QKSTDIMNAMLSKLYDVMFAKKVPEIIRKTEDRSESFSLFSTKG-KGDPKNR---NVNFA TUPGBGS_81_PE2 NOISO QKATDIMDAMLGKLYTVMFK-KCPETMRKTKDKAESYSLISMKG-MGDPKHR---NVNFA TURTRGS_2687_PE3 NOISO QNTADIMEAMLKRLVCALLGEKKE-------TKSQSLSYASLKAGCHDPKCKNQ-SLEFS TURTRGS_791_PE4 NOISO QKATDIMDAMLSKLYSVIFAKKPPETVRETKDKSESYSLMSVKG-TSDPKNR---NVSFA MATCH CONSENSUS Q?A?DIM?AML??L??????????????????K??S????S?K????DPK????????F?

AILMEGL192563_1_1_PE3 NOISO AMKAEMK---GKDKGKMKPEQ----YKSLTSAEKVSEHILKESLTIWN-QKQGNQGKM-- AILMEGL192757_1_1_PE6 NOISO TMKSEGK-----LREKMYSPAS-KPEKEKSCAETLSEHIIKEGLTFWHKNQQ-KEGKSPG ANOCA41_2_PE10 NOISO SLKGGIH-----TREKVRT------DMGQTSAQKVGETIIKDGISMLRSKAGGGKCSD-- ANOCA55_2_PE10 NOISO AAKTE-----------------SFKEKEATCAETVGNHIIKEGLSMWHQKQQ-NENVGSN BOVIN5_115_PE4 NOISO SMKSEGK-----VRERVCTPTP-KP--EKSCVETLGEHIIKEGLTLWHNSQQ-KEGISAC BOVINX_56_PE6 NOISO SVKAEMK---GKDKCKVKQEE----CKSLTSAEKVSEHILKESLTMWN-QKQCNQGKM-- CALJA9_18_PE6 NOISO -MRSEAK-----LREKMCSEAK-SE--KKTCAETLGEHIIKEGLTLWHKN-Q-KECKSPG CALJAX_49_PE37 ENSCJAG00000003006 TMKAEMK---GNDKQ-MKSDP----CKSLTSAEKVGEHILKEGLTMWN-QKQGNPWKM-- CALJAX_49_PE38 ISOFORMIN TMKAEEV---MKFAK-EQ-----------QQDEAMGN-VARKQL---------LDWLL-- CANFA27_45_PE5 NOISO SMKSEGK-----LKEKMYSPAS-KPEKEKSCAETLGEHIIKEGLTFWHTNQQ-KEGKSPG CANFAX_44_PE4 NOISO AVKAEMK---GKDKGKMKPEQ----CKSLTSAEKVGEHILKESLTMWN-QKQGNQGKM-- CAVPO107_3_PE7 NOISO -MKSEAK-----LKEKMYST-C-KPQKEKTCIETVGEHIIKEGLNMWHKNHQ-KDCKSPC CAVPO158_3_PE2 NOISO AMKAEMK---GKDKGK-KSDQ----CKSLTSAEKVGEHILKESLTMWN-QKQGNPCKM-- CHOHOGS_1972_PE1 NOISO XMISEPN-----SGKSVHS--A-FKSEEKTCAETVGEHIIKEGLTLWHKNQQ-KKCKSPG DIPORGS_3763_PE1 NOISO AMKAEMK---GKDKCRTKPDP----CKSLTSAERVSEHILKESLNMWN-QKQGCPIKM-- DIPORGS_92_PE2 NOISO -MKSEAK-----IRERMYST-C-KPEKEKTCMETLGEHIIRQGLTMWHKNHQ-KPSRATD ECHTEGS_126_PE2 NOISO TMKSEAK-----FREKIYSPEP-TP--EKSCAETLGEHIIKESLTLWRKSQQ-KDCKSPG ERIEUGS_141_PE2 NOISO SMKSEGR-----MRENTYTATC-KPEKEKSCVETLGEHFIKEGLSLWHKNQN-KDVKSPG GORGO12_5_PE11 NOISO -MKSETK-----LRAKMYSEPK-SE--EETCAKTLGEHIIKEGLTLWHKSQQ-KECQSLG GORGOX_53_PE5 NOISO TMKAEMK---ERDKGKMKSDP----CKSLTSAEKVGEHILKEGLTIWN-QKQGNSCKV-- HORSE6_34_PE8 NOISO TMKSEGK-----LREKMFCHAS-KPEDEKTCAKTLGEHLIKEGLTLWHKNQQ-REGKFPS HORSEX_41_PE23 ISOFORMIN AMKAEMK---GKDQGKMRPEQ----CKSLTSAEKVGEHILKESLTMWN-QKQGNQGKM-- HORSEX_41_PE24 ENSECAG00000024064 AMKAEMK---GKDQGKMRPEQ----CKSLTSAEKVGEHILKESLTMWN-QKQGNQGKM-- HS12_PE132 NOISO -MKSETK-----LREKMYSEPK-SE--EETCAKTLGEHIIKEGLTLWHKTQQ-KECKSLG HSX_PE989 ENSG00000147081 TMKAEMK---ERDKGKMKSDP----CKSLTSAEKVGEHILKEGLTIWN-QKQGNSCKV-- HSX_PE990 ISOFORMIN TMKAEMK---ERDKGKMKSDP----CKSLTSAEKVGEHILKEGLTIWN-QKQGNSCKV-- HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN TMKAEMK---ERDKGKMKSDP----CKSLTSAEKVGEHILKEGLTIWN-QKQGNSCKV-- LOXAF15_51_PE10 NOISO TMKSEAK-----FREKMYCPSP-KP--EKSCVETLGEHIIKQGLTLWHKNQQ-KDCKSPG LOXAF56_1_PE2 NOISO AMKAEMK---GKDKGKMKPEQ----CKSLTSAEKVSEHILKESLTMWN-QKQGNQGKV-- MACEUGS_5645_PE1 NOISO AMKAEMMKG-GKDKGKMKPDP----CKSLTSAEKVSEHILKESLTMWNQKQRDK-----I MACMU11_5_PE11 NOISO -MKSETK-----LREQMYSEPK-SE--EETCAKTLGEHIIKEGLTLWHKSQQ-KECKSLG MACMUX_49_PE3 ENSMMUG00000023060 TMKAEMK---GRDKGKMKSDP----CKTLTSAEKVGEHILKEGLTIWN-QKQGNPCKV-- MACMUX_49_PE4 ISOFORMIN TMKAEMK---GRDKGKMKSDP----CKTLTSAEKVGEHILKEGLTIWN-QKQGNPCKV-- MICMUGS_1141_PE1 NOISO -MKSEAK-----LREKMYSPVP-KPEKPKTCAETLGEHIIKEGLSLWHKSQQ-KECKSPG MONDO8_118_PE12 ENSMODG00000018285 SMKAEAK-----LREKPCTPCPSKTDKDKTCAETLGEHIIKEGLTLWHKNHQ-KETKSPG MONDO8_118_PE13 ISOFORMIN SMKAEAK-----LREKPCTPCPSKTDKDKTCAETLGEHIIKEGLTLWHKNHQ-KETKSPG MONDO8_118_PE14 ISOFORMIN SMKAEAK-----LREKPC------------------------------------------ MONDOX_75_PE19 ENSMODG00000011265 AMKAEMMKGGGKDKGKMKPDQ----CKSLTSAEKVSEHILKESLTMWNQKQTGGQTKCHA MONDOX_75_PE20 ISOFORMIN AMKAEMMKGGGKDKGKMKPDQ----CKSLTSAEKVSEHILKESLTMWNQKQTGGQTKCHA MONDOX_75_PE21 ISOFORMIN AMKAEMMKGGGKDKGKMKPDQ----CKSLTSAEKVSEHILKESLTMWNQKQTGGQTKCHA MONDOX_75_PE22 ISOFORMIN AMKAEMMKGGGKDKGKMKPDQ----CKSLTSAEKVSEHILKESLTMWNQKQTGGQTKCHA MOUSE6_PE2191 NOISO -MKSESK-----LKENLFST-C-KLEKEKTCAETLGEHIIKEGLHMWHKSQQ-KS---PG MOUSEX_PE25 ENSMUSG00000050089 AMKAEMK---GKDKCKSKADPC---CKSLTSAERVSEHILKESLTMWNNQKQGNQGKV-- MOUSEX_PE26 ISOFORMIN AMKAEMK---GKDKCKSKADPC---CKSLTSAERVSEHILKESLTMWNNQKQGNQGKV-- MOUSEX_PE27 ISOFORMIN AMKAEMK---GKDKCKSKADPC---CKSLTSAERVSEHILKESLTMWNNQKQGNQGKV-- MYOLUGS_84_PE2 NOISO TMKSEGK-----LKERMYSPPC-KP--EKTCVETLGEHIIKEGLSLWHKSQN-KEGKSPD ORNANULTRA315_PE1 ENSOANG00000013980 VMKAEMK---GKDKDKGKSGQ----TKSLTSAEKVGEHILKESLTMWNQKQQGQQGQQAK ORNANULTRA315_PE2 ISOFORMIN VMKAEEV---MKFAKERQLD------------DAVG-NITRKQLLDWLLANL-------- OTOGAGS_1660_1_PE8 NOISO -MKSEAK-----MREKMYSPMP-KPEK-KTCVETLGEHIIKEGLIMWHKNQQ-KECKSPG PANTR12_5_PE12 NOISO -MKSETK-----LREKMYSEPK-SE--EETCAKTLGEHIIKEGLTLWHKSQQ-KECKSLG PANTRX_50_PE18 NOISO ------------------------------------------------------------ PIG5_63_PE6 NOISO SMKSEGK-----LREKICSHSP-KPETEKSCAETLGEHIIKEGLTLWHKSQQ-KEGKSPA PIGX_44_PE24 NOISO AMKAETK---GKDKGKMKPEE----CKPLTSAEKVGEHILKESLTMWN-QKQGNPGKM-- PONPY12_5_PE10 NOISO -MKSETK-----LREKMYSEPK-SE--EDTCAKTLGEHIIKEGLTLWHKSQQ-KECKSLG PONPYX_51_PE6 NOISO TMKAEMK---ERDKGKMKSDP----CKSLTSAEKVGEHILKEGLTIWN-QKQGNPCKV-- PROCAGS_115_PE2 NOISO TMKSEAN-----FIERMCPPPP-KP--EKSCVETLGEHIIKQGLTLWHKKQQ-KDCKSPG PTEVAGS_177_PE4 NOISO SMKSEGK-----LRENVYCPPH-KPE-EKSCAETLGEHIIKEGLTLWHKSQN-KEGQFPG RABIT8_32_PE14 NOISO -MRSEAK-----LREKMYS-AP-KPEKEKTCAETLGEHIIKEGLTMWHKSQQ-KECKSPG RAT4_PE1735 NOISO -MKSESK-----LKENLFSA-C-ISEKEKTCAETLGEHIIKEGLNMWHKSQQ-NS---PG RATX_PE275 NOISO AMKAEMK---GKDKGKTKGDPC---CKSLTSAERVSEHILKESLTMWNNQKQGTQGRV-- SORARGS_3987_PE1 NOISO AMKAEMK---GKDKGKMKSDT----CKSLTSAEKVGEHILKESLTMN--QKQGNPSKM-- SPETRGS_89_PE2 NOISO -MKSEAK-----VKEKIYSS-G-KSEKEKTCAETLGEHIIKEGLTMWHKTQK-KECKSPD TARSYGS_2113_PE1 NOISO -MKSVDE-----LREKVYPA-S-NPAKEKTCAETLSEHIIKEGLSLWHDSQQ-NKCKSPG TUPGBGS_81_PE2 NOISO -MKSEAK-----LKEKVYSPH--KP--EKTCAETLGEHIIKEGLTMWHKNQQ-KECKSPG TURTRGS_2687_PE3 NOISO AMKAEMK---GKGKGKMKPEK----CKSLTSAEKGSEHTLKESLTMWN-QNQGSQGKM-- TURTRGS_791_PE4 NOISO SMKSEGK-----LREKIGSPAP-KPEKEKTCVETLGEHIIQEGLSLWHKNQQ-KEGKSPD MATCH CONSENSUS ?MK?E???????????????????????????E???EHI?KE?L??W?????????????

AILMEGL192563_1_1_PE3 NOISO AD-----------KAC--------------------------TS-KDEKREKISPSTDSL AILMEGL192757_1_1_PE6 NOISO FQ---RATFAAPNKQY-KPVADIPLGYP----LDTCNLTPPM--HHQEKPENFMCDSDSW ANOCA41_2_PE10 NOISO -------------------------------------------RPHDKRPEKSSTTTEFL ANOCA55_2_PE10 NOISO VQAK--------------PA------------------------WNLENQDVGNLATDSW BOVIN5_115_PE4 NOISO LQ---GSPFVTPKRQY-KPVPDFPLGFP----FDPCNFSLPM--QCPEKPENFMCDSDSW BOVINX_56_PE6 NOISO PS-----------KTC--------------------------PH-KEEKREKISPSTDSL CALJA9_18_PE6 NOISO FQ---HAACEAPNTQC-KPAPDISFEYP----EGTCNFSPPQ--YPPEKPENFMFDSDSW CALJAX_49_PE37 ENSCJAG00000003006 AT-----------KVS--------------------------CN-KDEKREMISASTDSL CALJAX_49_PE38 ISOFORMIN TS-----------L---------------------------------------------- CANFA27_45_PE5 NOISO FQ---RATFAAPNKQY-KPVPDIPLGYP----LDTCNLSPPM--HHREKPENFICDSDSW CANFAX_44_PE4 NOISO PG-----------KVC--------------------------AN-KEEKREKISPSTDSL CAVPO107_3_PE7 NOISO PQ---RAKSATPNEQD-SPVSDSPLED-----RETCNLSPSL--CHPEDVENFMCSSDSW CAVPO158_3_PE2 NOISO AA-----------KLC--------------------------AS-KDEKKENISSSTDSL CHOHOGS_1972_PE1 NOISO FQ---HATFTAPNKQG-RPIPDVP--------EGICNLSPPM--CHPEKPENFMCDSDSW DIPORGS_3763_PE1 NOISO PP-----------KIC--------------------------PS-KEDKREKISPSTDSL DIPORGS_92_PE2 NOISO PE---------PGLAA-DPPS-----DS----PDVCDLSPPL--PYPESMENFMCDADSW ECHTEGS_126_PE2 NOISO PQ---RAAFSVFNKEC-APGPDNPVECI----RETCN-SPRT--GGPEKVENVMYDSESW ERIEUGS_141_PE2 NOISO FQ---RASFDTPNKQF-RPTPDIPLDFP----LDTCGFSPPM--CPQEKPENFMCESDSW GORGO12_5_PE11 NOISO FQ---HAAFEAPNTQC-KPASDISFEYP----EDIGNLSPPP--YPPEKPENFMYDSDSW GORGOX_53_PE5 NOISO AT-----------KAC--------------------------SN-KDEKGEKINASTDSL HORSE6_34_PE8 NOISO LQ---QATFAAPNEQC-KPTPESLLGYP----LDTCNFIPPM--HDPEKLENFMCDSGSW HORSEX_41_PE23 ISOFORMIN TS-----------KAC--------------------------VN-REEKREKISPSTDSL HORSEX_41_PE24 ENSECAG00000024064 TS-----------KAC--------------------------VN-REEKREKISPSTDSL HS12_PE132 NOISO FQ---HAAFEAPNTQR-KPASDISFEYP----EDIGNLSLPP--YPPEKPENFMYDSDSW HSX_PE989 ENSG00000147081 AT-----------KAC--------------------------SN-KDEKGEKINASTDSL HSX_PE990 ISOFORMIN AT-----------KAC--------------------------SN-KDEKGEKINASTDSL HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN AT-----------KAC--------------------------SN-KDEKGEKINASTDSL LOXAF15_51_PE10 NOISO FQ---RATFEAPNKQY-QPPPDIPAEYT----QETYN-SPPM--HHPEKFENFMYDSDSW LOXAF56_1_PE2 NOISO SG-----------KLC--------------------------SN-KEEKREKISPSTDSL MACEUGS_5645_PE1 NOISO HG-----------KV---------------------------GTSREDKREKISPSTDSL MACMU11_5_PE11 NOISO FQ---HAACEAPNTQC-KPSPDISFEYP----EDICNLSPPP--YPPEKPENFICDSDSW MACMUX_49_PE3 ENSMMUG00000023060 AT-----------KAC--------------------------SN-KDEKGEKINASTDSL MACMUX_49_PE4 ISOFORMIN AT-----------KAC--------------------------SN-KDEKGEKINASTDSL MICMUGS_1141_PE1 NOISO FQ---RATCEALPKPC-KPAPEFPFECL----PDPCNISPPL--CCPERLENFMYDSDSW MONDO8_118_PE12 ENSMODG00000018285 LQRAS---FATSSRSVGKPNIKLPECHPPTTSPGPININ---ALSCQERQDNFLYSSDTW MONDO8_118_PE13 ISOFORMIN LQRAS---FATSS-----------------------------------RSDNFLYSSDTW MONDO8_118_PE14 ISOFORMIN ------------------------------------------------------------ MONDOX_75_PE19 ENSMODG00000011265 ST-----------KV---------------------------GPCREEKREKISPSTDSL MONDOX_75_PE20 ISOFORMIN ST-----------KV---------------------------GPCREEKREKISPSTDSL MONDOX_75_PE21 ISOFORMIN ST-----------KV---------------------------GPCREEKREKISPSTDSL MONDOX_75_PE22 ISOFORMIN ST-----------KV---------------------------GPCREEKREKISPSTDSL MOUSE6_PE2191 NOISO LERAA--------KLG-NAPQEVSFECP-----DPCEANPPHQPQPPENFANFMCDSDSW MOUSEX_PE25 ENSMUSG00000050089 TN-----------KVC--------------------------CTSKDEKREKISPSTDSL MOUSEX_PE26 ISOFORMIN TN-----------KVC--------------------------CTSKDEKREKISPSTDSL MOUSEX_PE27 ISOFORMIN TN-----------KVC--------------------------CTSKDEKREKISPSTDSL MYOLUGS_84_PE2 NOISO SQ-----CATTPSNQY-DPPPDFPLEYP----LDTCNFIPPV--HHLENPENFMCDSDSW ORNANULTRA315_PE1 ENSOANG00000013980 GQ-----------GKS--------------------------CYGREEKREKISPSTDSL ORNANULTRA315_PE2 ISOFORMIN ------------------------------------------------------------ OTOGAGS_1660_1_PE8 NOISO FQ---HPAGESPNKPC-KPAPDFPFEYP----QDPSDFSPPL--CHPERPENFMYDSDSW PANTR12_5_PE12 NOISO FQ---HAAFEAPNTQC-KPASDISFEYP----EDIGNLSPPP--YPPEKPENFMYDSDSW PANTRX_50_PE18 NOISO ------------------------------------------------------------ PIG5_63_PE6 NOISO FQ---CLPFAAPNKQY-KPAPDILLGFP----FDPCNLSPPL--QHLEKPENFMCDSDSW PIGX_44_PE24 NOISO AS-----------KPC--------------------------ISNKEEKREKISPSTDSL PONPY12_5_PE10 NOISO FQ---HAAFEAPNTQC-KPASDISFEYP----EDIGNLGPPP--YPPEKPENFMYDSDSW PONPYX_51_PE6 NOISO AT-----------KAC--------------------------SN-KDEKGEKINASTDSL PROCAGS_115_PE2 NOISO SQ---CAPFTAPSKQS-KPAPDTSAEYA----QDTCNSPP-M-----PHLENFMCDSDSW PTEVAGS_177_PE4 NOISO FQ---HAIFAAPNKQY-KPVPDIPLGYP----LDTCNLNPPM--HDPEKPENF--DSDSW RABIT8_32_PE14 NOISO FERFEHVTFSAPNKQY-KPAPDIPFGFP----QDTCTLSPLL--HQPEQPENFMYESDSW RAT4_PE1735 NOISO LERAT--------KQG-AVPQEVSFECP-----DPCEVNPLQQPQPPENFENFMCESDSW RATX_PE275 NOISO PN-----------KVC---------------------------PSKDEKREKISPSTDSL SORARGS_3987_PE1 NOISO PP-----------KAF--------------------------S--KDDKREQISPSTDSL SPETRGS_89_PE2 NOISO FE------PAATNKQK-NPAPDIPFEC-----LDPCSFSPSL--HFPEIPENFMCDSDSW TARSYGS_2113_PE1 NOISO LQ---RAASGAPNKQY-MSAPDIPLGYS----HDACDLSPPL--CHPEEPEDLMCDSKSG TUPGBGS_81_PE2 NOISO FQ---RAAFEMPDQQC-KSPPDIPCACP----EDISNFGPLL--CHPENADSIMYDSDSW TURTRGS_2687_PE3 NOISO AG-----------KAW--------------------------TN-KEEKREKISLSMDSL TURTRGS_791_PE4 NOISO LQ---CAPLAASNKQH-KPAPDSPSGVP----LDPSNLSPST--HHPEKLENFMHDSESW MATCH CONSENSUS ???????????????????????????????????????????????E??E??????DS?

AILMEGL192563_1_1_PE3 NOISO AKDLIVSALMLIQYHLTQQAKGKDAFEEERPG----STMGYMTQSGQYEKCASGQSAKAL AILMEGL192757_1_1_PE6 NOISO AKDLIISALLLIQYHLAQGGSTDAQSFT--------------------EAAGG------A ANOCA41_2_PE10 NOISO AKDLILTALMLIQQHLLTQYKEPVVES-------NTSSFGYFEKG------GKHGS---- ANOCA55_2_PE10 NOISO ARDLIVTALMLIQYHLHQQENAIKEAGD--------------------CGRGSSKTGNTF BOVIN5_115_PE4 NOISO AKDLLVSALLLIQYHLAQGGNMDAQSFL--------------------EAAGT------S BOVINX_56_PE6 NOISO AKDLIVSALMLIQYHLTQQAKGKEACEDDCPP----GTTSYMTQSAQYEKCGGSQSAKAL CALJA9_18_PE6 NOISO AKDLIISALLLIQYHLAQGGRRDAQNFP--------------------EAAGT------T CALJAX_49_PE37 ENSCJAG00000003006 AKDLIVSALKLIQYHLTQQARGKDTCEEEYPD----STTSYMAQSTQYEKCGGAQSAKAL CALJAX_49_PE38 ISOFORMIN ------------------------------------------------------------ CANFA27_45_PE5 NOISO AKDLIVSALLLIQYHLAQGGSMDAQSFL--------------------EAAGS------T CANFAX_44_PE4 NOISO AKDLIVSALTLIQYHLTQQAKGKDACEEDCPG----STTGYMTQSAQYEKCGSGQSAKAL CAVPO107_3_PE7 NOISO AKDLIVSALLLIQYHLAQGGKMDPQSFL--------------------EAATT------T CAVPO158_3_PE2 NOISO AKDLIVSALRLIQYHLTQQAKGKDVLDEDCSG----SSLGYMAQSTQYEKCGSGQNARTL CHOHOGS_1972_PE1 NOISO AKDLIVSALLLIQYHLAQGGSMDAQSFL--------------------EAASN------T DIPORGS_3763_PE1 NOISO AKDLIVSALMLIQYHLTHQAKGKDPCEEDCPS------SSYMAQSAQYEKCGGNQSAKAL DIPORGS_92_PE2 NOISO GKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAAAT------T ECHTEGS_126_PE2 NOISO AKDLIVSALLLIQYHLAQGGRMDGQSFL--------------------EAAGN------T ERIEUGS_141_PE2 NOISO AKDLLVSALLLIQYHLAQGGNMDAQSFL--------------------EAAGN------T GORGO12_5_PE11 NOISO AKDLIVSALLLIQYHLAQGGRRDAQSFL--------------------EAAGT------P GORGOX_53_PE5 NOISO AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPG----STMGYMAQSTQYEKCGGGQSAKAL HORSE6_34_PE8 NOISO AKDLLISALLLIQYHLAQGGSMDPQSFL--------------------EAAGS------T HORSEX_41_PE23 ISOFORMIN AKDLIVSALMLIQYHLTQQAKGKDLHEEDCPG----SSTSYTAQSAQYEKCGSGQTAKAL HORSEX_41_PE24 ENSECAG00000024064 AKDLIVSALMLIQYHLTQQAKGKDLHEEDCPG----SSTSYTAQSAQYEKCGSGQTAKAL HS12_PE132 NOISO AEDLIVSALLLIQYHLAQGGRRDARSFV--------------------EAAGT------T HSX_PE989 ENSG00000147081 AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPG----STMGYMAQSTQYEKCGGGQSAKAL HSX_PE990 ISOFORMIN AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPG----STMGYMAQSTQYEKCGGGQSAKAL HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPG----STMGYMAQSTQYEKCGGGQSAKAL LOXAF15_51_PE10 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAATN------T LOXAF56_1_PE2 NOISO AKDLIVSALMLIQYHLTQQAKGKDSFEDDCSG----STMGYMAQSAQYEKCGSGQSAKAL MACEUGS_5645_PE1 NOISO AKDLIVSALMLIQYHLTQQAKGKDALEEPESPTT----MGYMAQGTHYEKSGSGQSAKAL MACMU11_5_PE11 NOISO AKDLIVSALLLIQYHLAQGGRRDAQSFL--------------------EAAGT------T MACMUX_49_PE3 ENSMMUG00000023060 AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPG----STMGYMAQSTQYEKCGGGQSAKAL MACMUX_49_PE4 ISOFORMIN AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPG----STMGYMAQSTQYEKCGGGQSAKAL MICMUGS_1141_PE1 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAAAT------T MONDO8_118_PE12 ENSMODG00000018285 AKDLIVSALLLIQYHLAQGGSMDAQSFL--------------------EAAGT------T MONDO8_118_PE13 ISOFORMIN AKDLIVSALLLIQYHLAQGGSMDAQSFL--------------------EAAGT------T MONDO8_118_PE14 ISOFORMIN ------------------------------------------------------------ MONDOX_75_PE19 ENSMODG00000011265 AKDLIVSALMLIQYHLTQQAKGKDGLEEPVIEQPASTMAYSMTQGGHYEKCGSGQSAKAL MONDOX_75_PE20 ISOFORMIN AKDLIVSALMLIQYHLTQQAKGKDGLEEPVIEQPASTMAYSMTQGGHYEKCGSGQSAKAL MONDOX_75_PE21 ISOFORMIN AKDLIVSALMLIQYHLTQQAKGKDGLEEPA-----------------------------L MONDOX_75_PE22 ISOFORMIN AKDLIVSALMLIQYHLTQQAKGKDGLEEP--------------------KCGSGQSAKAL MOUSE6_PE2191 NOISO AKDLIVSALLLIQYHLAQGGKMDAQSFL--------------------EAAAS------T MOUSEX_PE25 ENSMUSG00000050089 AKDLIVSALMLIQYHLTQQAKGKDPCEEECPG----SSMGYMSQSAQYEKCGGGQSSKSL MOUSEX_PE26 ISOFORMIN AKDLIVSALMLIQYHLTQQAKGKDPCEEECPG----SSMGYMSQSAQYEKCGGGQSSKSL MOUSEX_PE27 ISOFORMIN AKDLIVSALMLIQYHLTQQAKGKDPCEEECPG----SSMGYMSQSAQYEKCGGGQSSKSL MYOLUGS_84_PE2 NOISO AKDLLVSALLLIQYHLAQGGSMDAQSFL--------------------EAAGR------T ORNANULTRA315_PE1 ENSOANG00000013980 AKDLIVSALMLIQYHLTQQA-------------------KYSAQGAHYEKSGSNQSTKAL ORNANULTRA315_PE2 ISOFORMIN ------------------------------------------------------------ OTOGAGS_1660_1_PE8 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAAAT------T PANTR12_5_PE12 NOISO AKDLIVSALLLIQYHLAQGGRRDAQSFV--------------------EAAGT------T PANTRX_50_PE18 NOISO ------------------------------------------------------------ PIG5_63_PE6 NOISO AKDLIVSALLLIQYHLAQGGSMDAQSFL--------------------EAAAS------T PIGX_44_PE24 NOISO AKDLIVSALMLIRYHLTQQAKGKDAFEDDCPG----STMGYMTQSAQYEKCGGNQSAKAL PONPY12_5_PE10 NOISO AKDLIVSALLLIQYHLAQGGRRDVQSFL--------------------EAAGT------T PONPYX_51_PE6 NOISO AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPG----STMGYMAQSTQYEKCGGGQSAKAL PROCAGS_115_PE2 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAATH------T PTEVAGS_177_PE4 NOISO AKDLIVSALLLIQYHLAQGGSMDAQSFL--------------------EAAGS------T RABIT8_32_PE14 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAAGS------T RAT4_PE1735 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAAAS------T RATX_PE275 NOISO AKDLIVSALMLIQYHLTQQAKGKDPCEEECPG----SSMGYMSQSAQYEKSGGGQSSKSL SORARGS_3987_PE1 NOISO AKDLIVS-ITLIQYYLSQQAKGKDASDDDGCS----PASSYLTQTAQYEKRGTGE-AIAL SPETRGS_89_PE2 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAAGS------S TARSYGS_2113_PE1 NOISO AKDLIVSALLLIQHHLALGGRMDAGSFL--------------------EAAST------T TUPGBGS_81_PE2 NOISO AKDLIVSALLLIQYHLAQGGRMDAQSFL--------------------EAAGS------T TURTRGS_2687_PE3 NOISO AKDLIVSALRLIQYYLTQQAKGKDAF-KDCPC----STTSYMTQSAQYKKCRRSQSVKAL TURTRGS_791_PE4 NOISO ARXXXXXXXXXXXXXLAQGGSMDAQSLV--------------------KAAGG------T MATCH CONSENSUS AKDLIVSAL?LIQYHL?Q??????????????????????????????E???????????

AILMEGL192563_1_1_PE3 NOISO SMKHLESRG---APGPSTS-----LKENQQLDSQNLDMSNIVLMLIQKLLSESPFNCEDL AILMEGL192757_1_1_PE6 NOISO NLPANKS----PIVSDEPSPKSPQM-EGDQEEAEKKDLMSVFFNFIRNLLGETIFKSDHS ANOCA41_2_PE10 NOISO -------------KSSHNY-----KGDPQQQEYQRGEIQSALLSIIQKVLQEAGFSVDEC ANOCA55_2_PE10 NOISO GFMSQDKSGNAAMLKQYDSLKKSD--DEQSEANPENDMSSVVVMLIQKLINETGAY---- BOVIN5_115_PE4 NOISO NLYPTKS----PAVSHESSLRSPQV-GADPEEVEKKDLMSVFFNFIRNLLSETIFKSDHS BOVINX_56_PE6 NOISO SMKHLETRG---APGPSTS-----MKDNQHLDSQKLDMSNMVLSLIQKLLNESPFNCEDL CALJA9_18_PE6 NOISO NFNANKS----PVVPDESCLKTAHN-VDDQEQAEKKDLMSVFFNFIRNLLSETVFERGHC CALJAX_49_PE37 ENSCJAG00000003006 SVKHLESHG---DPGSSTS-----LKENQGIDSQKMDMSNIVLMLIQKLLNES-SNCEDP CALJAX_49_PE38 ISOFORMIN ------------------------------------------------------------ CANFA27_45_PE5 NOISO NLPANKS----PVVSDESSLKSPQM-GGDQEEAEKKDLMSVFFNFIRNLLSETIFKSDRS CANFAX_44_PE4 NOISO SMKHLESHG---APGPSTS-----LKDNQQLDSQKLDMSNIVLMLIQKLLSESPFNCDDL CAVPO107_3_PE7 NOISO SHPANKL----SAAPNESK---YPHKVCDQEQTGKKDLMSVFFNFIRNLLSETIFKSDNC CAVPO158_3_PE2 NOISO SMKHLESRG---GPGPSTS-----LKENQQLASQKLDMSNIVLSLIQKLLSESPFSCDEL CHOHOGS_1972_PE1 NOISO NLPATKS----PTVSDESTTKSPDA----KEETEKKDLMSIFFNFIRNLLGETIFKSDHS DIPORGS_3763_PE1 NOISO SMKHLETRG---NCGPSTS-----AKENQQLDSQKMDMSNIVLSLIQKLLNENTFNCDEL DIPORGS_92_PE2 NOISO NFPNSGP----E----ESRPN-PPPRVCDQEQAEKKDLMSVIFNFIRNLLGETIFKGDRG ECHTEGS_126_PE2 NOISO SLPPMKP----PVSPDAASLKHPHFMGDN--QEEKKDLMSVVFNFIRNLLGETIFKVQ-- ERIEUGS_141_PE2 NOISO SLPK-KS----PTVCEDPSLKSPLL--GGQEESGKKDLMSVFFNFIRNLLSETIFKNDRC GORGO12_5_PE11 NOISO NFPANEP----PVVPDESCLKSAPI-VGDQEQAEKKDLRSVFFNFIRNLLSETIFKHDQS GORGOX_53_PE5 NOISO SVKQLESHR---APGPSTC-----QKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDP HORSE6_34_PE8 NOISO NFPINKS----PEVSDEPR---IHL-GGDQEEAEKKDLKSVFFNFIQNLLSETIFKSDHS HORSEX_41_PE23 ISOFORMIN SMKHLESRG---APGPSTS-----LKENQHVNCQKLDMSNIVLTLIQKLLGESSFNCDDI HORSEX_41_PE24 ENSECAG00000024064 SMKHLESRG---APGPSTS-----LKENQHVNCQKLDMSNIVLTLIQKLLGESSFNCDDI HS12_PE132 NOISO NFPANEP----PVAPDESCLKSAPI-VGDQEQAEKKDLRSVFFNFIRNLLSETIFKRDQS HSX_PE989 ENSG00000147081 SVKQLESHR---APGPSTC-----QKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDP HSX_PE990 ISOFORMIN SVKQLESHR---APGPSTC-----QKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDP HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN SVKQLESHR---APGPSTC-----QKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDP LOXAF15_51_PE10 NOISO NLPATKS----PAAFDESALKTPHFVRGDQEAAEKKDLMSVFFNFIRNLLSETIFKSDHS LOXAF56_1_PE2 NOISO SMKHLESRG---APGPSTS-----LKENQQLDSQKLDMSNIVLMLIQKLLSESPFNCDDL MACEUGS_5645_PE1 NOISO SMKHLESRG---S-QHAGP-----STSPKELDTQKLDMSNIVLMLIQKLLSESPFSLDDQ MACMU11_5_PE11 NOISO NFPANEP----PVVPDESCLKSAPI-VGDQEQAEKKDLRSVFFNFIRNLLSETIFKRDQS MACMUX_49_PE3 ENSMMUG00000023060 SVKHLESHR---APGPSTC-----QKENQPLDSQKMDMSNIVLMLIQKLLNENPFKCEDP MACMUX_49_PE4 ISOFORMIN SVKHLESHR---APGPSTC-----QKENQPLDSQKMDMSNIVLMLIQKLLNENPFKCEDP MICMUGS_1141_PE1 NOISO NFPANKL----PVVPDESCLRSSHV-VCDKEQSEKKDLMSVFFNFIRNLLGETIFKNDRS MONDO8_118_PE12 ENSMODG00000018285 TKLAAAP--KSNQNSEQSSLGSSRL-GGTHEEAEKKDLMSVFFNFIRNLLGETIFKCDDS MONDO8_118_PE13 ISOFORMIN TKLAAAP--KSNQNSEQSSLGSSRL-GGTHEEAEKKDLMSVFFNFIRNLLGETIFKCDDS MONDO8_118_PE14 ISOFORMIN ------------------------------------------------------------ MONDOX_75_PE19 ENSMODG00000011265 SMKHLESRS---TAQCAGP-----STSPKELDTQKLDMSNIVLMLIQKLLSESPFSLEEQ MONDOX_75_PE20 ISOFORMIN SMKHLESRS---TAQCAGP-----STSPKELDTQKLDMSNIVLMLIQKLLSESPFSLEEQ MONDOX_75_PE21 ISOFORMIN SMKHLESRS---TAQCAGP-----STSPKELDTQKLDMSNIVLMLIQKLLSESPFSLEEQ MONDOX_75_PE22 ISOFORMIN SMKHLESRS---TAQCAGP-----STSPKELDTQKLDMSNIVLMLIQKLLSESPFSLEEQ MOUSE6_PE2191 NOISO NFPTNKPPPPSPVVQDECKLKSPPHKICDQEQTEKKDLMSVIFNFIRNLLSETIFKSSRN MOUSEX_PE25 ENSMUSG00000050089 SMKHFETRG---APGPSTC-----MKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDEL MOUSEX_PE26 ISOFORMIN SMKHFETRG---APGPSTC-----MKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDEL MOUSEX_PE27 ISOFORMIN SMKHFETRG---APGPSTC-----MKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDEL MYOLUGS_84_PE2 NOISO NFPTNKA----PVVSAETNLKSSHM-EGNQEETEKKDLMSVFFNFIRNLLGETIFKND-- ORNANULTRA315_PE1 ENSOANG00000013980 SMKHMEATRNGPHAGPSNQ-----PSKEAQMDTHKLDISNLVLAVIQKLLSDNFNIDGDQ ORNANULTRA315_PE2 ISOFORMIN ------------------------------------------------------------ OTOGAGS_1660_1_PE8 NOISO NFPPNKP----PVVPDESCLKSPQV-VGDKEQAEKKDLMSVFFNFIRNLLGETIFKNDRS PANTR12_5_PE12 NOISO NFPANEP----PVVPDESCLKSAPI-VGDQEQAEKKDLRSVFFNFIRNLLSETIFKRDQS PANTRX_50_PE18 NOISO ------------------------------------DMSNIVLMLIQKLLNENPFKCEDP PIG5_63_PE6 NOISO NLQANKS----PAVSDESSLKPPHV-GGDQEEAEKKDLMSVFFNFIRNLLRETIFKSNRS PIGX_44_PE24 NOISO SMKHLESHG---APGPSTS-----LKENQHLDSQKLDMSNIVLSLIQKLLGESPFHCEDL PONPY12_5_PE10 NOISO NFPANEP----PVVPDESCLKSAPI-VGDQEQAEKKDLRSVFFNFIRSLLSETIFKRDQS PONPYX_51_PE6 NOISO SVKQLESHR---APGPSTC-----QKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDP PROCAGS_115_PE2 NOISO SLPTIKS----PAAADESTLKTPRFVGAEQEAAEKKDLMSVFFNFIRNLLSETFFKSDRS PTEVAGS_177_PE4 NOISO NFPANKT----PAVPDETKPKSAHM-EGNQEEAEKKDLMSVFFNFIRNLLRETIFKSDRS RABIT8_32_PE14 NOISO NLPTKKC----PVVPDESSLKIPHV-VGDQEQAEKKDLMSVFFNFIRNLLGETIFKSDNS RAT4_PE1735 NOISO NFPTK----SSPVVHDEGKVKSPPLKICEQEQTEKKDLMSVIFNFIRNLLSETIFKGSRN RATX_PE275 NOISO SMKHFESRG---APGPSTC-----AKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDEL SORARGS_3987_PE1 NOISO SMEHLETHG---FSGASTS-----PKDSQHPNCQETDMSNMVLSLIQKIPIDGPVRLGGS SPETRGS_89_PE2 NOISO NFPITKT----PVVLDESSLKTPHV-VCDQEQSEKKDLMSVFFNFIRNLLGETIFKGDNS TARSYGS_2113_PE1 NOISO NFSTNKP----PEVSNKSC--------VNQEQAEKKTLMSVFFNFIRNLLSETIFKSGHS TUPGBGS_81_PE2 NOISO NFPSKKS----PVVPDESSLKSPHL-VGDREQAEKKDLMSVFFNFIRNLLGETIFKDRSC TURTRGS_2687_PE3 NOISO SMKHLESRG---APGSSTS-----QKENEHLDSQRLDMSNIVLSLIQKLLSESSFNCGDL TURTRGS_791_PE4 NOISO NLQASKS----PAISDESGIRSPHM-GVDQEAAEKKDLMSVFFNFIRNLLGETIFKSDRS MATCH CONSENSUS ??????????????????????????????????K?D????????I??LL?E??F?????

AILMEGL192563_1_1_PE3 NOISO CEGENKR---------S-EPRT-SRVTSVSKKPDKGEEQCQ--------------DNQEL AILMEGL192757_1_1_PE6 NOISO SEPKVPEQPVKEEYSHQCERPV-------TPSPVKLSEGD---EAGGTFAGLTKMVASQL ANOCA41_2_PE10 NOISO EITKNVK---------QYSYD------DRSTKTTKSKQYCS--------------DVD-- ANOCA55_2_PE10 NOISO KSPEVPGNSGSSE---------------------------VDHSYDDAIAGLTKMILDQF BOVIN5_115_PE4 NOISO CDPK----ATKEDNSPQCERPV-------TPSPAKLNECD---ETGGAFAGLTKMVANKL BOVINX_56_PE6 NOISO CEGENKH---------S-EIRT-NKSTSIFKKSDREEEQGQ--------------DNREV CALJA9_18_PE6 NOISO SEPKVPEQLVKED-TNLYERPL-------TSSPPKPCKDD---ETPGASSGLTKMVTNQL CALJAX_49_PE37 ENSCJAG00000003006 CEGENKH---------S-EPKV-NKATSMSQRPDKGEEQCQ--------------DHQEF CALJAX_49_PE38 ISOFORMIN ------------------------------------------------------------ CANFA27_45_PE5 NOISO SEPKVPEQPIKEEYSHQCERPI-------TPSPIKLSEGD---ETGGTFAGLTKMVANQL CANFAX_44_PE4 NOISO CESENKR---------S-EPRT-NKAASMSKKSDRGEEQCQ--------------DNQEL CAVPO107_3_PE7 NOISO PESKV---LIKEESVNLCERPV-------TPCSTKLCEDT---ETGSPFSELTKMVASQV CAVPO158_3_PE2 NOISO CEGENKS---------S-EPRT-NKASSVARRCDRGEVQCQ--------------DNAEL CHOHOGS_1972_PE1 NOISO CEPKV-----KEEDSNPCERST-------TPSPTKGCEGD---EAIGPLAGLTKMVANQL DIPORGS_3763_PE1 NOISO CEGESKR---------C-EPKP-SKACTS-KK--PEKEECP--------------DNLDI DIPORGS_92_PE2 NOISO CASKVPEQPAREE--CQCERPL-------TPCPTRLCDE----EVDGTLSGLTKMVASQL ECHTEGS_126_PE2 NOISO -DPKGPEQPAKEE-SQPCESPT-------TPSPTKGCDGE---ESGGVLAGLTKMVANQL ERIEUGS_141_PE2 NOISO SA--KPEQPMKEE-NCQCERPV-------TPCPIKTCEGE---EVSEPFAGLTKMVANQF GORGO12_5_PE11 NOISO PEPKVPEQPVKED-RKLCERPL-------ASSPPRLYEGD---ETPGALSGLTKMVVNQI GORGOX_53_PE5 NOISO CEGESKC---------S-EPRA-SKAASMSNRSDKGEEQCQ--------------EHQEL HORSE6_34_PE8 NOISO SEVKVPEQPIREGEGRQCERPV-------TPSPIKLSEDD---EAGGPFAGLTKMVVNQL HORSEX_41_PE23 ISOFORMIN SEGENKH---------S-EPST-SRGTSMFKRPDRGEEQCQ--------------ENQEL HORSEX_41_PE24 ENSECAG00000024064 SEGENKH---------S-EPST-SRGTSMFKRPDRGEEQCQ--------------ENQEL HS12_PE132 NOISO PEPKVPEQPVKED-RKLCERPL-------ASSPPRLYEDD---ETPGALSGLTKMAVSQI HSX_PE989 ENSG00000147081 CEGENKC---------S-EPRA-SKAASMSNRSDKAEEQCQ--------------EHQEL HSX_PE990 ISOFORMIN CEGENKC---------S-EPRA-SKAASMSNRSDKAEEQCQ--------------EHQEL HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN CEGENKC---------S-EPRA-SKAASMSNRSDKAEEQCQ--------------EHQEL LOXAF15_51_PE10 NOISO SEPKEPEHPAKED-INQCERPI-------TPSPTKVCDGE---EAGGAFAGLTKMVTNQL LOXAF56_1_PE2 NOISO SEGENKR---------S-ESRT-SKAASISKKPDRGEEQCQ--------------ENQEL MACEUGS_5645_PE1 NOISO CEGESKR---------T-ESKS-KVSSSTSKRSEKGEEHFQ--------------DHQEF MACMU11_5_PE11 NOISO SEPKVPEQPVKED-RKLCDRPL-------APSPPKLCEDD---ETPGALSGLTKMVVSQI MACMUX_49_PE3 ENSMMUG00000023060 CEGENKH---------S-EPRA-SKATYMSKRSDKGEEQCQ--------------DHQEL MACMUX_49_PE4 ISOFORMIN CEGENKH---------S-EPRA-SKATYMSKRSDKGEEQCQ--------------DHQEL MICMUGS_1141_PE1 NOISO CELNVPEHPVNEEDSNRCERPA-------TPSPIKLCEEE---EAGGTFSGLTKMVVSQL MONDO8_118_PE12 ENSMODG00000018285 SEAKAPSHHSKEEEGSFPEVTP-------PNCPPKHCGGYGGGGGTGAIAGLTKMVANQL MONDO8_118_PE13 ISOFORMIN SEAKAPSHHSKEEEGSFPE-----------------------------------MVANQL MONDO8_118_PE14 ISOFORMIN ------------------------------------------------------------ MONDOX_75_PE19 ENSMODG00000011265 CEGESKR---------A-ESKS-KVSSCTSKRSDRGEEHFQ--------------DHQEF MONDOX_75_PE20 ISOFORMIN CEGESKR---------A-ESKS-KVSSCTSKRSDRGEEHFQ--------------DHQEF MONDOX_75_PE21 ISOFORMIN CEGESKR---------A-ESKS-KVSSCTSKRSDRGEEHFQ--------------DHQEF MONDOX_75_PE22 ISOFORMIN CEGESKR---------A-ESKS-KVSSCTSKRSDRGEEHFQ--------------DHQEF MOUSE6_PE2191 NOISO CESNVHEQNTQEEEIHPCERPKTPCERPITPPAPKFCEDEE--ATGGALSGLTKMVANQL MOUSEX_PE25 ENSMUSG00000050089 TESDNKR---------CCDPRS-SKAAPMAK---RPEEQCQ--------------DNAEL MOUSEX_PE26 ISOFORMIN TESDNKR---------CCDPRS-SKAAPMAK---RPEEQCQ--------------DNAEL MOUSEX_PE27 ISOFORMIN TESDNKR---------CCDPRS-SKAAPMAK---RPEEQCQ--------------DNAEL MYOLUGS_84_PE2 NOISO SEPKVPEQPIKED---LCERPV-------PPCPIKVSEGD---ESGGTLAGLAKMVT--- ORNANULTRA315_PE1 ENSOANG00000013980 AETESRR---------S-DFHP-PKVSSLTK------RGEQ--------------EHQEI ORNANULTRA315_PE2 ISOFORMIN ------------------------------------------------------------ OTOGAGS_1660_1_PE8 NOISO CEAKMPEQPVKEK--TSCERPA-------TPCPVKLYEGE---ESGGALSGLTKMVVNQL PANTR12_5_PE12 NOISO PEPKVPEQPVKED-RKLCERPL-------ASSPPRLYEDD---ETPGALSGLTKMVVNQI PANTRX_50_PE18 NOISO CEGENKC---------S-EPRA-SKAASMSNRSDKGEEQCQ--------------EHQEL PIG5_63_PE6 NOISO SDPK----PTKEEDSPQCERPV-------TPSPIKFSEGD---EAGGTFAGLTKMVANQL PIGX_44_PE24 NOISO CEGENKR---------S-EPRT-NKASSMSKRPDRGEDQCQ--------------DNQEL PONPY12_5_PE10 NOISO PEPKVPEQPVKED-RKLCERPL-------ASSPPRLHEDD---ETPGALSGLTKVVVNQI PONPYX_51_PE6 NOISO CEGENKR---------S-EPRV-SKEASMSKRSDKGEEQCQ--------------EHQEL PROCAGS_115_PE2 NOISO SEPKVPEHLVKED-SNQCERPI-------TPPLVKVCDGE---ETGGAFSGLTKMVANQL PTEVAGS_177_PE4 NOISO SERKVPEQPTKEEYSHLCERPV-------TPSPIKLSEGD---EAGGAFAGLTKMVANSL RABIT8_32_PE14 NOISO PEPKMPEQPAKEESSRHCERPV-------TPSPIKLNEGD---ETGGAFSGLTKMVANQL RAT4_PE1735 NOISO CESKAHEQIIKEEEINLCERPLSPCERPMSPPVPKFCEDEE--ATGGALSGLTKMVANQL RATX_PE275 NOISO SESENKR---------CCDSRS-KQAAPVAK---RPEDQSQ--------------DSTEM SORARGS_3987_PE1 NOISO GEGENRR---------S-EPGG-NGSTSISTRPERGEEQCQ--------------ESQDL SPETRGS_89_PE2 NOISO CESKAPEKSDKEKDCNQGERPM-------TPSPK-LSEGD---E-AGAFSGLTKMVANQL TARSYGS_2113_PE1 NOISO PEPKVPEEPVREEDRHRCERTM-------TPSSASPCECD---EAGGPLSGMTKMIVNQP TUPGBGS_81_PE2 NOISO SKVDH---PVKEESAPXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXX TURTRGS_2687_PE3 NOISO CEGENKR---------S-EPRT-DKGASMSKRPDKGEEKCQ--------------DNQEL TURTRGS_791_PE4 NOISO SEPKPT----K--ERQSCERPV-------SPSPIKLNEGD---EAGGTFAGLTKKVANQL MATCH CONSENSUS ?E????????????????E?????????????????????????????????????????

AILMEGL192563_1_1_PE3 NOISO DFISGMKQVNCQFIDQLVESVMKLCLIMAKYSNDGAALAELEEQ------------AALA AILMEGL192757_1_1_PE6 NOISO D-----GHMNGQMVEHLMDSVMKLCLIIAKSCDSP--LAELGD------KSGDESRPTSA ANOCA41_2_PE10 NOISO --SENMEQINKKFIDQLMESVMKLCTYMTKSPDFVVEDYS-DEQ------------DSMA ANOCA55_2_PE10 NOISO DVNKAEGGGSGPFFDNLVDTVTKLCLMIAKYSN-P--ESGLGDMVDADDASG----PL-- BOVIN5_115_PE4 NOISO D-----GHMNGQMVDHLMDSVMKLCLIIAKSCDSP--LAELGD-----DKSGDASRPTSA BOVINX_56_PE6 NOISO DFVGGMKQVNRQFIDQLVESVMKLCLIMAKYSNNEAALTDLEEQ------------ASSS CALJA9_18_PE6 NOISO D-----GNMNGKMVEHLMDSVMKLCIIIAKSCDTS--LTELED-----DKSGNVSRLMSA CALJAX_49_PE37 ENSCJAG00000003006 DFTSGIKQMNQHFIDRLVESVMKLCLIMAKYTKNGAALAELEEQ------------AAST CALJAX_49_PE38 ISOFORMIN ------------------------------------------------------------ CANFA27_45_PE5 NOISO D-----GHMNGQMVEHLMDSVMKLCLIIAKSCDSP--LAELGD-----DKSGDASRPTSA CANFAX_44_PE4 NOISO DFISGMKQVNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQ------------AALA CAVPO107_3_PE7 NOISO D-----GNMSRQMVEQLMDSVMKLCVIIAKSCDPS--LTELGD-----DKCGDASRPNSA CAVPO158_3_PE2 NOISO DFVSGMKQMNRQFIDQLVESVMKLCMIMANYSNREA-FAELEEQ------------EAGF CHOHOGS_1972_PE1 NOISO D-----GHMNGQMVEHLMDSVMKLCLIIAKSCDSP--LAELGD-----DKSGDASRPTSA DIPORGS_3763_PE1 NOISO DFASGMKQMNRQF----------------------------------------------- DIPORGS_92_PE2 NOISO D-----GRAPGHMLDHLVDSVMKLCLIIAKSCDSP--LAELGD-----DKSGDASRPTSA ECHTEGS_126_PE2 NOISO E-----GHMNGKFVEHLTDSVMKLCLIIAKSCDSP--LAELGD-----EKSGDASRPASA ERIEUGS_141_PE2 NOISO D-----GQMNGQVVEHLMDSVMKLCLIIAKSCDSP--LAELGD-----EKCGDASRPTSA GORGO12_5_PE11 NOISO D-----GRMSGQMVEHLMNSVMKLCVIIAKSCDAS--LAELGDDKLGDDKSGDASRLTSA GORGOX_53_PE5 NOISO DCTSGMKQVNGQFIDKLVESVMKLCLIMAKYSNNGAALAELEEQ------------AASA HORSE6_34_PE8 NOISO D-----GHMNGQMIEHLTDSVMKLCLIIAKSCDSP--LAELGD-----DKSGDASRPTSA HORSEX_41_PE23 ISOFORMIN DFASGLKQVNRQFIDQLVESVMKLCLIMTKYGNNGAALDELEEQ------------AAS- HORSEX_41_PE24 ENSECAG00000024064 DFASGLKQVNRQFIDQLVESVMKLCLIMTKYGNNGAALDELEEQ------------AASV HS12_PE132 NOISO D-----GHMSGQMVEHLMNSVMKLCVIIAKSCDAS--LAELGD-----DKSGDASRLTSA HSX_PE989 ENSG00000147081 DCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQ------------AASA HSX_PE990 ISOFORMIN DCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQ------------AASA HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN DCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQ------------AASA LOXAF15_51_PE10 NOISO D-----GNMNGQMVEQLMDSVMKLCLIIAKSCDSP--LAELGD-----DKSGDASRPTSA LOXAF56_1_PE2 NOISO DFISGMKQVNRQFIDQLVESVMKLCLIMAKYSPSKRR----------------------- MACEUGS_5645_PE1 NOISO DFISGMKQVNRQFVDQLVESVMKLCLIMAKYSNNGAGLAELEEQ------------AA-T MACMU11_5_PE11 NOISO D-----GHMSGQMVEHLMNSVMKLCVIIAKSCDSS--LAELGDDKLGD-----DNRLTSA MACMUX_49_PE3 ENSMMUG00000023060 DFISGMKQVNWQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQ------------AASA MACMUX_49_PE4 ISOFORMIN DFISGMKQVNWQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQ------------AASA MICMUGS_1141_PE1 NOISO D-----GQMGGKMVDHLVDSVMKLCLIIAKSCDSP--LAELGD-----DKCGDASRPPSA MONDO8_118_PE12 ENSMODG00000018285 D-----GNMNGQMVEQLMDSVMKLCLIIAKSCDTP--LGDLGD-----EKSGDASRPTSA MONDO8_118_PE13 ISOFORMIN D-----GNMNGQMVEQLMDSVMKLCLIIAKSCDTP--LGDLGD-----EKSGDASRPTSA MONDO8_118_PE14 ISOFORMIN ------------------------------------------------------------ MONDOX_75_PE19 ENSMODG00000011265 DFISGMKQVNRQFVDQLVESVMKLCLIMAKYSNNGAGLAELEEQ------------AG-A MONDOX_75_PE20 ISOFORMIN DFISGMKQVNRQFVDQLVESVMKLCLIMAKYSNNGAGLAELEEQ------------AG-A MONDOX_75_PE21 ISOFORMIN DFISGMKQVNRQFVDQLVESVMKLCLIMAKYSNNGAGLAELEEQ------------AG-A MONDOX_75_PE22 ISOFORMIN DFISGMKQVNRQFVDQLVESVMKLCLIMAKYSNNGAGLAELEEQ------------AG-A MOUSE6_PE2191 NOISO D-----NCMNGQMVEHLMDSVMKLCLIIAKSCDSP--LSELGE-----EKCGDASRPNSA MOUSEX_PE25 ENSMUSG00000050089 DFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQ------------AAL- MOUSEX_PE26 ISOFORMIN DFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQ------------AAL- MOUSEX_PE27 ISOFORMIN DFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQ------------AAL- MYOLUGS_84_PE2 NOISO ------SHMNGQMIEHLMDSVMKLCVIIAKSCDSP--LAELGD-----DKSGDASRPAST ORNANULTRA315_PE1 ENSOANG00000013980 DFVSGIKQVNRQFVDQLVESVMKLCLIMAKYSN-GAGLPEAEEP------------AMSY ORNANULTRA315_PE2 ISOFORMIN ------------------------------------------------------------ OTOGAGS_1660_1_PE8 NOISO D-----GQMNGKMLDHLMDSVMKLCLIIAKSCDTP--LAELGD-----DKCGDASRPSSA PANTR12_5_PE12 NOISO D-----GHMSGQMVEHLMNSVMKLCVIIAKSCDAS--LAELGDDKLGDDKSGDASRLTSA PANTRX_50_PE18 NOISO DCTSGMKQVNGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQ------------SASA PIG5_63_PE6 NOISO D-----GHMNGQMVEHLMDSVMKLCLIIAKSCDSP--LGELGD-----DKSGDASRPVSA PIGX_44_PE24 NOISO DFISGMKQVNRQFIDQLVESVMKLCLIMAKYSNNRAALAELEEQ------------AALA PONPY12_5_PE10 NOISO D-----SHMSGQMVEHLMNSVMKLCVIIAKSCDSS--LAELGDDKLGDDKSGDASRLTSA PONPYX_51_PE6 NOISO DCISGMKQANWQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQ------------AASA PROCAGS_115_PE2 NOISO G-----GQMNGQMVDQLVDSVMK-CLIIAKSCDSP--LXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_177_PE4 NOISO D-----GHMNGEMIEHLMDSVMKLCLIIAKSCDSP--LAELGD-----DKSGDASRPPSA RABIT8_32_PE14 NOISO D-----GHMNGQMVEHLMDSVMKLCLIIAKSCDSP--LAELAE-----DKSGDAGRPNSA RAT4_PE1735 NOISO D-----GCMNGQMVEHLMDSVMKLCLIIAKSCDSP--LSELGD-----EKCGDASRPSSA RATX_PE275 NOISO DFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQ------------AAL- SORARGS_3987_PE1 NOISO DFISGMKQMNREFIDQLVESVMKLCLIMAKYNNKGAPFNELEEQ------------ASP- SPETRGS_89_PE2 NOISO D-----GNMNGQMVDHLVDSVMKLCLIIAKSCDSP--LAELGD-----EKSGDASRPNSA TARSYGS_2113_PE1 NOISO D-----GDMDGKMVEHLMDSVMKLCLIIAKSCDSH--LTELGD-----ENSGDAGGPTTA TUPGBGS_81_PE2 NOISO ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXX-----XX-XXXXXXXXX TURTRGS_2687_PE3 NOISO DFISGMKQVSRQFIDQLVESVMKLCLIMAKYSNNGAALVELEEA------------AL-A TURTRGS_791_PE4 NOISO D-----DHMNKQMVEHLMDSVMKLCLIIAKSCDSP--LAEVES-----NKSGDTNRPTSS MATCH CONSENSUS D???????????????L??SVMKLC?I?AK???????L?EL???????????????????

AILMEGL192563_1_1_PE3 NOISO NNPN-YQVGSSGCS-----------------HDGAVSHNYQDTPGPEVIVNNQCS-TSSL AILMEGL192757_1_1_PE6 NOISO FPDSLYECLPVKGTGTAETLLKNAYQAIHNELRGISGQPPEGCAAPKVIVSNHSLSDTVR ANOCA41_2_PE10 NOISO -------GQKGR---------------------SGYSGKPLVPAGSEVIVNNQNANTSSQ ANOCA55_2_PE10 NOISO -----YSK----DIESGE---------------SRIGSGEDTLSHRKVVVTNQNAAENIH BOVIN5_115_PE4 NOISO FPESLYECLSTKGTGTAETFLQNAYQAIHNELRSLSAQPPEGCTAPKVIVSNHNLTDTVQ BOVINX_56_PE6 NOISO NNSNFYQTSGPRSS-----------------YEAGMSQSYQDSHGPEVIVNNQCS-TSSL CALJA9_18_PE6 NOISO FPDSLYECLPVKDTGTAEALLQNAYQAVHNLLRGVSGQAPEGCAAPKVIVSNHNLLDTVE CALJAX_49_PE37 ENSCJAG00000003006 --------SKPRCS-----------------HNNAMPQNYQDSPGHEVIVNNQCS-TNSL CALJAX_49_PE38 ISOFORMIN ------------------------------------------------------------ CANFA27_45_PE5 NOISO FPDSLYECLPVKGTGTAETLLQNAYQAIHNELRGISGQPPEGCTAPKVIVSNHSLSDTVQ CANFAX_44_PE4 NOISO NNPN-YQVGGSRCS-----------------QDGAMSQNHQDSPGPEVIVNNQCS-TSSL CAVPO107_3_PE7 NOISO LPDSLFECLPVKGTGTAEALLQNAYQNIHNELRCLSGQLLEGCAAPKVIVSNHNLTDTVQ CAVPO158_3_PE2 NOISO ------SNNVNRCG-----------------QEATMSR-NRDSPRPEVIVNNQCS-TSNL CHOHOGS_1972_PE1 NOISO FPDSIYECLPVKGTGTAEALLQNAYQAIHNELRGLSGRPPEGCMAPKVIVSNHNLCDTVQ DIPORGS_3763_PE1 NOISO ------------------------------------------------------------ DIPORGS_92_PE2 NOISO LPDSLYECLPARGTGTAEALLQNAYQAIHNELRGAYGQLPEGCAIPRVIVSNHNLTDTVQ ECHTEGS_126_PE2 NOISO FPDNLYECLPVKGTGTTETILQNAYQTIQNELRSLSGPSPEGCAVPKVIVSNQNLADTVQ ERIEUGS_141_PE2 NOISO FPDSLYECLPVKGTGTAEALLQNAYQAIHNELRCSSGQPPEGCMAPKVIVSNQNLTDTVQ GORGO12_5_PE11 NOISO FPDSLYECLPVKGTGSAEAVLQNAYQAIHNEMRGISGQPPEGCAAPKVIVSNHNLTDTVQ GORGOX_53_PE5 NOISO NKPNF---RGTRCI-----------------HTGAMPQNYQDSLGHEVIVNNQCS-TNSL HORSE6_34_PE8 NOISO LPDSLYACLPAKGTETAEALVQNAYQAIHNELRG-SGQPPEECAAPKVIVSNHNLTDTVQ HORSEX_41_PE23 ISOFORMIN -------ASGSRRS-----------------QSGVMPQNYQDSSGPQVIVNNHCS-TSSL HORSEX_41_PE24 ENSECAG00000024064 NNAN-YQASGSRRS-----------------QSGVMPQNYQDSSGPQVIVNNHCS-TSSL HS12_PE132 NOISO FPDSLYECLPAKGTGSAEAVLQNAYQAIHNEMRGTSGQPPEGCAAPTVIVSNHNLTDTVQ HSX_PE989 ENSG00000147081 NKPNF---RGTRCI-----------------HSGAMPQNYQDSLGHEVIVNNQCS-TNSL HSX_PE990 ISOFORMIN NKPNF---RGTRCI-----------------HSGAMPQNYQDSLGHEVIVNNQCS-TNSL HSX_PE992 ISOFORMIN ------------------------------------------------------------ HSX_PE994 ISOFORMIN NKPNF---RGTRCI-----------------HSGAMPQNYQDSLGHEVIVNNQCS-TNSL LOXAF15_51_PE10 NOISO FPDNLYECLPVKGTGTAEALLQNAYQAIHKELRGISGHPPEGCAAPKVVVSNQNLTDTVQ LOXAF56_1_PE2 NOISO ------------------------------------------------------------ MACEUGS_5645_PE1 NOISO EPS-F-RASNSRCA-----------------QDAMMSHSFHDNPGPEVIVNNQSS-TSNL MACMU11_5_PE11 NOISO FPDSLYECLPVKGTGSAEALLQNAYQAIHNEMRGISGQPPEGCAAPKVIVSNHNLTDTVQ MACMUX_49_PE3 ENSMMUG00000023060 DKPNF---RGTRCI-----------------HSSAMPQNYQDSLGHEVIVNNQCS-TNSL MACMUX_49_PE4 ISOFORMIN DKPNF---RGTRCI-----------------HSSAMPQNYQDSLGHEVIVNNQCS-TNSL MICMUGS_1141_PE1 NOISO FADNLYECLPAKGTGTAEALLQNAYQAIHNELKGISGQPPEGCTAPKVIVSNHNLTDTVQ MONDO8_118_PE12 ENSMODG00000018285 FPDSFFECLPVKGTGTAEALLQNAYQAIHNELRGMSIHPPEGTNTPKVIVSNHNIADTVQ MONDO8_118_PE13 ISOFORMIN FPDSFFECLP-------------------------------GTNTPKVIVSNHNIADTVQ MONDO8_118_PE14 ISOFORMIN ----------------------------------MSIHPPEGTNTPKVIVSNHNIADTVQ MONDOX_75_PE19 ENSMODG00000011265 NPANFRASSNSRCA-----------------QDAMMSHSYHESPGPEVIVNNQSS-TSNL MONDOX_75_PE20 ISOFORMIN NPANFRASSNSRCA-----------------QDAMMSHSYHESPGPEVIVNNQSS-TSNL MONDOX_75_PE21 ISOFORMIN NPANFRASSNSRCA-----------------QDAMMSHSYHESPGPEVIVNNQSS-TSNL MONDOX_75_PE22 ISOFORMIN NPANFRASSNSRCA-----------------QDAMMSHSYHESPGPEVIVNNQSS-TSNL MOUSE6_PE2191 NOISO FPDNLYECLPVKGTGTAEALLQNAYLTIHNELRGLSGQPPEGCEIPKVIVSNHNLADTVQ MOUSEX_PE25 ENSMUSG00000050089 ------VGSGSRCG-----------------RDAMMSQNYSETPGPEVIVNNQCS-TTNL MOUSEX_PE26 ISOFORMIN ------VGSGSRCG-----------------RDAMMSQNYSETPGPEVIVNNQCS-TTNL MOUSEX_PE27 ISOFORMIN ------VGSGSRCG-----------------RDAMMSQNYSETPGPEVIVNNQCS-TTNL MYOLUGS_84_PE2 NOISO FPDSFYECLPVKGTGTAEAVLQNAYQAIHNELRGVSGQLPEGCASTKVVVSNQNLIDTVQ ORNANULTRA315_PE1 ENSOANG00000013980 --------RGSH-------------------CDSVVPSHCQDAPGPEVIVNNQNS-TGNL ORNANULTRA315_PE2 ISOFORMIN ------------------------------------------------------------ OTOGAGS_1660_1_PE8 NOISO LPDSLYECLPVKGTGTAEAILQNAYQAIHNELRGISGQPLEGCAAPKVIVSNHNLTDTVQ PANTR12_5_PE12 NOISO FPDSLYECLPVKGTGSAEAVLQNAYQAIHNEMRGISGQPPEGCAAPKVIVSNHNLTDTVQ PANTRX_50_PE18 NOISO NKPNF---RGTRCI-----------------HSGAMPQNYQDSLGHEVIVNNQCS-TNSL PIG5_63_PE6 NOISO FPENLYECLPTKGTGTAETLLQNAYQAIHNELRGMSGQPLEGCTAPKVIVSNHNLTDTVQ PIGX_44_PE24 NOISO NNAN-YQVSGPKRS-----------------HDGGMSQNYQDSPGPEVIVNNQCS-TSSL PONPY12_5_PE10 NOISO FPDSLYECLPVKGTGSAEALLQNAYQAIHNEMRGISGQPPEGCAAPKVIVSNHNLTDTVQ PONPYX_51_PE6 NOISO NKPNF---RGTRCI-----------------HRGAMPQNYQDSLGHEVIVNNQCS-TNSL PROCAGS_115_PE2 NOISO XXXXXXXXXXXXXXXXXXXX---XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_177_PE4 NOISO FPDSLYECLPVKGTGTAEALLQNAYQTIHNELRCISGQPPEGCAAPKVIVSNHNLTDTVQ RABIT8_32_PE14 NOISO FPDNLYECLPVKGTGTAEALLQNAYQAIHNELRGISGQPLEGCA-PKVIVSNHNLTDTVQ RAT4_PE1735 NOISO FPDNLYECLPVKGTGTAEALLQNAYLAIHNELRGLSGQPPEGCEIPKVIVSNHNLADTVQ RATX_PE275 NOISO ------ASNGPRCG-----------------REAVMSQSYPETPGPEVI----------- SORARGS_3987_PE1 NOISO SNTNFRNCPPPKSC-----------------HESMAPQSFQERPGPEVIVNNQCA-TSSL SPETRGS_89_PE2 NOISO FPESLYECLPVKGTGTAEALLQNAYQAIHNELRCASGQPPEGCTAPKVIVSNHNLSDTVQ TARSYGS_2113_PE1 NOISO FPDNLYDCLAVKGTETAEAILQNAYQAIHSELRGASRQSPEECPAPKIIVSNHKLMDTSP TUPGBGS_81_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TURTRGS_2687_PE3 NOISO NNPN-YQAGGPRCS-----------------HDAAMSQNYQDSPGTEVIVNNQCS-TSSL TURTRGS_791_PE4 NOISO SPDSLHECLSTKGTGAAEILLKNAYETIYNELRGISAPLPEGSAAPKVIVSSHNLADTVQ MATCH CONSENSUS ???????????????????????????????????????????????VIV?N????????

AILMEGL192563_1_1_PE3 NOISO QKQLQAVLQWIAASEFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAK AILMEGL192757_1_1_PE6 NOISO NKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGCSVGEVLQSVLRYEK ANOCA41_2_PE10 NOISO NKELQAILQWMAASHFQVPNLTFMNENDEELKKLPQLADKAAKKGASVGDILQEVMRYFE ANOCA55_2_PE10 NOISO NKQLQAVLQWVAASQLNVPVLYFMDDDEETLNKLQQLSMVAVERGYSVGEVMQAVLKYEK BOVIN5_115_PE4 NOISO NKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVEKGRSVGEVLQSVLRYEK BOVINX_56_PE6 NOISO QKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAK CALJA9_18_PE6 NOISO NKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGCSVGKVLQSVLCYEK CALJAX_49_PE37 ENSCJAG00000003006 QKQLCAVLQWIAASQFNVPMLYFMEDDDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAK CALJAX_49_PE38 ISOFORMIN ------------------------------------------------------------ CANFA27_45_PE5 NOISO NKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGRSVGEVLQSVLRYEK CANFAX_44_PE4 NOISO QKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAK CAVPO107_3_PE7 NOISO NKQLQAVLQWVAASELNVPVLYFAGDDEEIQKKLLQLSAAAVEKGRSVGEVLQLVLRYEK CAVPO158_3_PE2 NOISO QKQLQAVLQWIAASEFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAK CHOHOGS_1972_PE1 NOISO NKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGRSVGEVLQSVLRYEK DIPORGS_3763_PE1 NOISO ------------