Alignment of the gene Family HOG000220909 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL192364_1_2_PE1 NOISO KTS-ILLMFLWGLSCALPVARYQNTESESSEEWKGHLAQTPTPPL--ESSESSEESKVSS BOVIN6_109_PE5 NOISO KTT-ILLMFLWGLSCALPVARYQNTESKSSEEWKGHLAQTPTPPL--ESSESSEESKLSS CALJA3_112_PE25 ENSCJAG00000006215 KIS-ILLMFFWGLSCALPVARYQKNESESSEEWKGHLDQAPTPPL--ESSESSEGSKVSS CALJA3_112_PE26 ISOFORMIN KIS-ILLMFFWGLSCALPVTRYQKNESESSEEWKGHLDQAPTPPL--ESSESSEGSKVSS CALJA3_112_PE27 ISOFORMIN KIS-ILLMFFWGLSCALPVTRYQKNESESSEEWKGHLDQAPTPPL--A------------ CALJA3_112_PE28 ISOFORMIN KIS-ILLMFFWGLSCALPVSIRAGIYEKIFSVLQGHLDQAPTPPL--ESSESSEGSKVSS CAVPO33_2_PE1 NOISO KTV-ILLALLWGLACALPVARYQDTASESSEEWTGHLVSSPTPSVIFQGNESSQESKVSS DASNO27458_PE1 NOISO KTS-ILLMFLWGLSCAFPVTRYQNTESGSSEESKGHLAQTPTPPL--ESSESSDESKVSS DIPOR3670_PE2 NOISO KTS-ILFMLLWTLSCALPVTRHQNAESGETGA-LDQLAQLATPSP--GSSESSEESKVSS ERIEU376204_PE1 NOISO ------------------VARYQNTEYESSKEWKGSLAQTPAPPL--ESSESSEESKLSS FELCAGS_2911_PE1 NOISO KTS-ILLLFLWGLSCALPXXXXXXXXXXXXXXXXGHLAQTPTPPL--XXXXXXXXXXXXX GORGO4_101_PE3 NOISO -------MFLWGLSCALPVTRYQNNESEGSEEWKGHLAQAPTPPL--ESSESSEGSKVSS HORSE3_53_PE4 NOISO -------MFLWGFSCALPVTRYQNTESKSSEEWKGHLAQTPTPAL--ESSESSEESKVSS HS4_PE2000 ENSG00000152592 KIS-ILLMFLWGLSCALPVTRYQNNESEDSEEWKGHLAQAPTPPL--ESSESSEGSKVSS HS4_PE2001 ISOFORMIN KIS-ILLMFLWGLSCALPVTRYQNNESEDSEEWKGHLAQAPTPPL--A------------ LAMPAGS_2384_PE8 NOISO KTS-ILLMFLWGLSCALPVAKHQNTESKSSEEWEDHLAQTPTPPL--ESSESSEESKVSS LOXAF30_8_PE8 NOISO KTS-ILLVFLWGLSCALPVARYQNTESKSSEEWKGRLAKTPTLPS--ESSESSEESKDSS MACEUGS_6036_PE1 NOISO KTT-LLLIFFWGFSCALPVAKYLNTDSESSEELKXXXXXXXXXXX--ESSESSEESKDSS MACMU5_83_PE10 ENSMMUG00000011114 KIS-ILLTFLWGLSCALPVTRYQNNESESSEEWKGHLTQAPTPPL--ESSESSKGSKVNP MACMU5_83_PE11 ISOFORMIN KIS-ILLTFLWGLSCALPVTRYQNNESESSEEWKGHLTQAPTPPL--A------------ MICMUGS_2664_PE1 NOISO RPS-VLLMFLWGLACAFPVARYQNDDSEHSKEWKGHLAQASTPAL--ESSESSEGSPISS MONDO5_54_PE14 ENSMODG00000020734 KTP-FLLIVFWGLSCALPVTRYLNTDSESSEELTSWICYTRKQAP--ESSESSEESKDSS MONDO5_54_PE15 ISOFORMIN KTP-FLLIVFWGLSCALPVTRYLNTDSESSEELT-------------ESSESSEESKDSS MONDO5_54_PE16 ISOFORMIN KTP-FLLIVFWGLSCALPVTRYLNTDSESSEELTSWICYTRKQAP--ESSESSEESKDSS MONDO5_54_PE17 ISOFORMIN KTP-FLLIVFWGLSCALPVTRYLNTDSESSEELT-------------M------------ MOUSE5_PE1652 NOISO KTV-ILLVFLWGLSCALPVARYHNTESESSEERTGDLAGSPPPPT--N-SESSEESQASP ORNANCONTIG263_1_PE12 ENSOANG00000013628 KTAFLLFICLWSLSWALPVARYQNTESESSEEWKGHLQRVRDRTT--ESSESSEESKDSS ORNANCONTIG263_1_PE13 ISOFORMIN KTAFLLFICLWSLSWALPVARYQNTESESSEEWKGHLQRVRDRTT--ESSESSEESKDSS ORNANCONTIG263_1_PE14 ISOFORMIN KTAFLLFICLWSLSWALPVARYQNTESESSEEWKQCLPNPF-FLP--ESSESSEESKDSS ORNANCONTIG263_1_PE15 ISOFORMIN KTAFLLFICLWSLSWALPVARYQNTESESSEEWKTKSSPNS----------------QPP OTOGAGS_3143_PE1 NOISO KTS-ILLMFLLGLSSAFPVARYQNNESESSEEWKGHLAQVSTPPL--ESGVSSERSQVSS PANTR4_94_PE4 ISOFORMIN ------------------------------------------------------------ PANTR4_94_PE5 ENSPTRG00000016262 KIS-ILLMFLWGLSCALPVARYQNNESEGSEEWKGHLAQAPTPPL--ESSESSEGSKVSS PANTR4_94_PE6 ISOFORMIN KIS-ILLMFLWGLSCALPVARYQNNESEGSEEWKGHLAQAPTPPL--A------------ PIG8_115_PE11 NOISO KTS-ILLMLLWGLSCALPVARYQNTESKSSEERKGQLAQTPAPPL--ESSESSEESKLSS PONPY4_95_PE3 ENSPPYG00000014917 KIS-ILLMFLWGLSCALPVARYQNNEAEGSEEWKGHLAQAPTPPL--ESSESSEGSKVSS PONPY4_95_PE4 ISOFORMIN ------------------------------------------------------------ PTEVA10005_PE2 NOISO KTS-LLLMLFWGLS-TLPVARYQNTESKSSEEWKGRLAQTQTPPL--ESSESSEESKVSS RABIT15_64_PE6 NOISO KTS-ILFMFLWGLTCALPVARYENTETESSEEWKDPLAPPPTPPL--EDSVSSEESKVSS RAT14_PE127 ENSRNOG00000002167 KTV-ILLTFLWGLSCALPVARYQNTESESSEERTGNLAQSPPPPM--N-SESSEESKVSP RAT14_PE128 ISOFORMIN KTV-ILLTFLWGLSCALPVARYQNTESESSEERTGNLAQSPPPPM--A------------ SPETRGS_3430_PE1 NOISO KTS-ILLICFWGLSCALPVARYQNTETESSEEWKGYLAQSPTPPT--ENSESSEESKVSS TUPGBGS_3327_PE1 NOISO RTS-VLLMFLLGVACALPDAKDKNMESEN--SLKGHLTPAKPTP-VMEGNESSEESKVSS TURTR108740_PE2 NOISO RTS-ILLMFLWGLSCALPVARYQNTESKSSEEWKGLLAQTPTPPL--ERSESSEESKVSS MATCH CONSENSUS K????L????WGLS?ALPV?RY?N??S??SEE????L???????????????????????

AILMEGL192364_1_2_PE1 NOISO EEQASE---DPSDSAESKEG--LNDHQYMHRPADGLPRNGG-KGG--DDKDDDEDDSGDD BOVIN6_109_PE5 NOISO EEQANE---DPSDSTESEEVLGLDDQQHVHRPAGGLSRRGG-SEG--DNKDDDEDESGDD CALJA3_112_PE25 ENSCJAG00000006215 EEQANE---DPSDSAESEERLGSDDHQYIYRPTGGFSRSTG-E-G--YDKDDDEDDSGDD CALJA3_112_PE26 ISOFORMIN EEQANE---DPSDSAESEERLGSDDHQYIYRPTGGFSRSTG-E-G--YDKDDDEDDSGDD CALJA3_112_PE27 ISOFORMIN ----NE---DPSDSAESEERLGSDDHQYIYRPTGGFSRSTG-E-G--YDKDDDEDDSGDD CALJA3_112_PE28 ISOFORMIN EEQANE---DPSDSAESEERLGSDDHQYIYRPTGGFSRSTG-E-G--YDKDDDEDDSGDD CAVPO33_2_PE1 NOISO EEQANE---DLSDSPETAEDLTSDDDHYVSRPAGGLARSAG-REG--DDKEDDEDDSGDD DASNO27458_PE1 NOISO EEQANE---DPSESSESEEGLGPDDHRNVYRPAGGLSRSGG-R-G--DDKDDDEDESGDD DIPOR3670_PE2 NOISO EEQVND---DPSDSAETVEHLDSADGQYIYRPAGGLAKSAG-TGG--HDKEDDEDDSGDD ERIEU376204_PE1 NOISO EEQTNE---DLSDSTESEEGLGDH--ESQYQPVGGLSRSRG-R----DDKDNEEDDSGDD FELCAGS_2911_PE1 NOISO XXXANE---DPSDSVESEEG--LDDHQHVHRPAGGLSRNGG-KEG--DDKDDDEDDSGDD GORGO4_101_PE3 NOISO EEEANE---DSSDSTESEEGLGSDDHQYIYRLAGGFSRSTG-KEG--DDKDDDEDDSGDD HORSE3_53_PE4 NOISO EEQANE---VPSDSAESEEG--LHDGQYVYRPASGLSWSGG-KDV--DDKDDDEDDSGDD HS4_PE2000 ENSG00000152592 EEQANE---DPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTG-KGG--DDKDDDEDDSGDD HS4_PE2001 ISOFORMIN ----NE---DPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTG-KGG--DDKDDDEDDSGDD LAMPAGS_2384_PE8 NOISO EEQANE---DPSDSTESEEGLSLDDHQYIHRPAGGFSSSGG-KEG--DGKDDDEDESGDD LOXAF30_8_PE8 NOISO EEQENE---DPSESSESEEGRGHDDRQYIYRPADGLSRRGG-KGG--LGPE--------- MACEUGS_6036_PE1 NOISO KEQINEDKMDYSDRTESEEDLGLNDQETVYRLSDSSFKSGI-KD---SDKNDDEDDSGDD MACMU5_83_PE10 ENSMMUG00000011114 EEHANE---DPSDSTESEEGLGSDDDQYIYRPAGGFSRSTG-KEG--DDKDDDEDDSGDD MACMU5_83_PE11 ISOFORMIN ----NE---DPSDSTESEEGLGSDDDQYIYRPAGGFSRSTG-KEG--DDKDDDEDDSGDD MICMUGS_2664_PE1 NOISO EEQADA---DPGDSPESQEG--PDARHHVQGPAGGPFRGAGGRGGAEKDEDNDEDDSGDD MONDO5_54_PE14 ENSMODG00000020734 KEQ---SKKDYSDSIESEEDLGLTDQESVYLQSDSSLKSGI-KE---DDKNDDEDDSGDD MONDO5_54_PE15 ISOFORMIN KEQ---SKKDYSDSIESEEDLGLTDQESVYLQSDSSLKSGI-KE---DDKNDDEDDSGDD MONDO5_54_PE16 ISOFORMIN KEQ---SKKDYSDSIESEEDLGLTDQESVYLQSDSSLKSGI-KE---DDKNDDEDDSGDD MONDO5_54_PE17 ISOFORMIN -NE---SKKDYSDSIESEEDLGLTDQESVYLQSDSSLKSGI-KE---DDKNDDEDDSGDD MOUSE5_PE1652 NOISO EGQANS---DHTDSSESGEELGYDRGQ--YRPAGGLSKSTG-T-G--ADKEDDEDDSGDD ORNANCONTIG263_1_PE12 ENSOANG00000013628 EEQVSE---DNSDSTESEEDL-----HRLYKPAMGPTKSIM-KEA--DGKDDDEDDSGDD ORNANCONTIG263_1_PE13 ISOFORMIN EEQVSE---DNSDSTESEEDL-----HRLYKPAMGPTKSIM-KEA--DGKDDDEDDSGDD ORNANCONTIG263_1_PE14 ISOFORMIN EEQVSE---DNSDSTESEEDL-----HRLYKPAMGPTKSIM-KEA--DGKDDDEDDSGDD ORNANCONTIG263_1_PE15 ISOFORMIN TSNVSE---DNSDSTESEEDL-----HRLYKPAMGPTKSIM-KEA--DGKDDDEDDSGDD OTOGAGS_3143_PE1 NOISO EEQANE---DPSDSTEXXXXXXXXXXXXXXXXXXXXXXXXX-XXX--XXXXXXXXXXXXX PANTR4_94_PE4 ISOFORMIN ------------------------------------------------------------ PANTR4_94_PE5 ENSPTRG00000016262 EEQANE---DPSDSTESEEGLGSDDHQYIYRLAGGFSRSTG-KEG--DDKDDDEDDSGDD PANTR4_94_PE6 ISOFORMIN ----NE---DPSDSTESEEGLGSDDHQYIYRLAGGFSRSTG-KEG--DDKDDDEDDSGDD PIG8_115_PE11 NOISO EEQAHE---DPSDSTESEEHMGLDGHQYSHRPAGGLAVSGG-KEG--EDKDDDEDESGDD PONPY4_95_PE3 ENSPPYG00000014917 EEQANE---DPRDSIESEEGLGSDDHQYIYRPAGGFSRSTG-KEG--DDKDDDEDDSGDD PONPY4_95_PE4 ISOFORMIN ------------------------------------------------------------ PTEVA10005_PE2 NOISO EEQADE---DSSDSTESEEGLGFDDHQYAHRPADDISRNGG-KEG--DDKDDDEDDSGDD RABIT15_64_PE6 NOISO EEQVSK---DSRDTTDSEEALISDDGQYLYRTAGGFSKS---------DKEDDEDDSGDD RAT14_PE127 ENSRNOG00000002167 EGQANS---DHTDSSESGEELGSDRSQ--YRPAGGLSKSAG-M-D--ADKEEDEDDSGDD RAT14_PE128 ISOFORMIN ----NS---DHTDSSESGEELGSDRSQ--YRPAGGLSKSAG-M-D--ADKEEDEDDSGDD SPETRGS_3430_PE1 NOISO EEQANV---DPSDSAELEDDLGSDDRQYVYRPAGGLSRSTG-K-E--EDKDDDEDDSGDD TUPGBGS_3327_PE1 NOISO EEQAYQ---DPSDSAKSEEDLGPDSHQYIHRPAGGLSRSTG-K-G--DDKADDEDDSGDD TURTR108740_PE2 NOISO KEQVNE---DPSDSTESEEGLGLDDPQYIHRPAGGLSRSGG-KEG--DDKDDDEDESGDD MATCH CONSENSUS ?????????D?SDS?ES?E??????????????????????????????K?DDED?SGDD

AILMEGL192364_1_2_PE1 NOISO TFGNDDNGPGPEKRQ-GGNSRHKSNEDSADTTQSGEDSALQGEDSAQD------TTSESR BOVIN6_109_PE5 NOISO TFGDDDGGPGPEERRSGGDSRLGSDEDSADTTRSREDSTPQGDEGARD------TTSESR CALJA3_112_PE25 ENSCJAG00000006215 TFGDDDNGLVPKDRQEGENSKLGSDEDSADTTQSSEEGAPQGQDSAQD------TTSESR CALJA3_112_PE26 ISOFORMIN TFGDDDNGLVPKDRQEGENSKLGSDEDSADTTQSSEEGAPQGQDSAQD------TTSESR CALJA3_112_PE27 ISOFORMIN TFGDDDNGLVPKDRQEGENSKLGSDEDSADTTQSSEEGAPQGQDSAQD------TTSESR CALJA3_112_PE28 ISOFORMIN TFGDDDNGLVPKDRQEGENSKLGSDEDSADTTQSSEEGAPQGQDSAQD------TTSESR CAVPO33_2_PE1 NOISO TFGDEDNSLGPRKDREGGISRLDSGEDSADTTQSREDSASRE-DSTEH------LASDSR DASNO27458_PE1 NOISO TFGDEDN---------GGNTSLGSEEYSSDATQASKDSTPQGDDSAQD------TISESG DIPOR3670_PE2 NOISO TFGDKDPGPGPEEGQEGGISRLDSDEDSADTTQSREDSTQ-------D------TT---- ERIEU376204_PE1 NOISO TFSEEDNSPGPEEGQ-GADSVLGSEEDSTDSTESRQD-------STQD------TTSESR FELCAGS_2911_PE1 NOISO TFGDDDNGPGPEETQ-EGNSRLKSNEDSADITQSREDSAPRGEDSAQD------TTSDSR GORGO4_101_PE3 NOISO TFGDDDSGPGPKDRQEGGNSRLGNDEDSDDTIQSSEESAPQGQDSAQD------TTSENK HORSE3_53_PE4 NOISO TFGDDDNGPGPEETQ-RGHSRLRSEEDSADNTQSREDSALRGEDSTQD------ITSESR HS4_PE2000 ENSG00000152592 TFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQD------TTSESR HS4_PE2001 ISOFORMIN TFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQD------TTSESR LAMPAGS_2384_PE8 NOISO TFGDDDSGPGPAER-QGGDSRLGSDEDSADTTQSREDSAPQGEDSAQD------TTSESR LOXAF30_8_PE8 NOISO -----------EGHE-GGNVRLQSDEDSADTTQSREDSTPQGEDSDQD------TTIESR MACEUGS_6036_PE1 NOISO TFVDIDNSQGSMERHQQEG-------KNCRWGRCQ------------TMLSD-KSVSES- MACMU5_83_PE10 ENSMMUG00000011114 TFGDNDSGPGPKDRQEGGNSRLGSDEDSDDTIQSSEEGAPQGQDSAQD------ITSESR MACMU5_83_PE11 ISOFORMIN TFGDNDSGPGPKDRQEGGNSRLGSDEDSDDTIQSSEEGAPQGQDSAQD------ITSESR MICMUGS_2664_PE1 NOISO TLGDDGRGPGPEEGQDGGHSRRGGDEDSAADTTSE------GDESARD------ATS--- MONDO5_54_PE14 ENSMODG00000020734 TFVDIDNGQGSMERHQQED-------DDSDTTLSNENSTADGEDGNHNVVSDESSQSESR MONDO5_54_PE15 ISOFORMIN TFVDIDNGQGSMERHQQED-------DDSDTTLSNENSTADGEDGNHNVVSDESSQSESR MONDO5_54_PE16 ISOFORMIN TFVDIDNGQGSMERHQQED-------DDSDTTLSNENSTADGEDGNHNVVSDESSQSESR MONDO5_54_PE17 ISOFORMIN TFVDIDNGQGSMERHQQED-------DDSDTTLSNENSTADGEDGNHNVVSDESSQSESR MOUSE5_PE1652 NOISO TFGDEDNDLGPEEGQWGGPSKLDSDEDSTDTTQSSEDSTSQ-ENSAQD------TPSDSK ORNANCONTIG263_1_PE12 ENSOANG00000013628 TFGDEENGQASIQRQEEESPFVGAGDDNTVGDDSEDYADTQR-----D--------YSSQ ORNANCONTIG263_1_PE13 ISOFORMIN TFGDEENGQASIQRQEEESPFVGAGDDNTVGDDSEDYADTQR-----D--------YSSQ ORNANCONTIG263_1_PE14 ISOFORMIN TFGDEENGQASIQRQEEESPFVGAGDDNTVGDDSEDYADTQR-----D--------YSSQ ORNANCONTIG263_1_PE15 ISOFORMIN TFGDEENGQASIQRQEEESPFVGAGDDNTVGDDSEDYADTQR-----D--------YSSQ OTOGAGS_3143_PE1 NOISO XXXXXXXXPLSEER-QGGNSRLGSDEDSADTTQSSEESVPQAEDSAQD------VTSESR PANTR4_94_PE4 ISOFORMIN ------------------------------------------------------------ PANTR4_94_PE5 ENSPTRG00000016262 TYGDDDSGPGPKDRQEGGYSRLGSDEDSDDTIQASEESAPQGQDSAQD------TTSESR PANTR4_94_PE6 ISOFORMIN TYGDDDSGPGPKDRQEGGYSRLGSDEDSDDTIQASEESAPQGQDSAQD------TTSESR PIG8_115_PE11 NOISO TLGDDDSGPGPEES----NSRLRSGEDSADTTQSREDSAPQGEVSAQD------TTSESR PONPY4_95_PE3 ENSPPYG00000014917 TFGDDDSGPGPKDRQEGGSSRLGSDEDSDDTIQSSEEGAPQGQDSAQD------TTSESR PONPY4_95_PE4 ISOFORMIN ------------------------------------------------------------ PTEVA10005_PE2 NOISO TLGDDDNGPGPEESQ-GGNSKLRSDEDSADTTQSREDSASQGEDSAQD------AASESR RABIT15_64_PE6 NOISO TFGDEDNGPGPKERQGGGNSELGSEEDSADNTQSRED-------SAQD------TTSDSR RAT14_PE127 ENSRNOG00000002167 TFGDEDNGPGPEERQWGGPSRLDSDEDSADTTQSSEDSTSQ-ENSAQD------TPSDSK RAT14_PE128 ISOFORMIN TFGDEDNGPGPEERQWGGPSRLDSDEDSADTTQSSEDSTSQ-ENSAQD------TPSDSK SPETRGS_3430_PE1 NOISO TFADEDNGPWPEERTGGGISRLGD--DSADATRSSEDSTS-PEDSAQD------TTSDSR TUPGBGS_3327_PE1 NOISO TLGEDDNGPRPEDRQEDGKSRQGSDENSADTTESSEDRAPEGQDSAQD------TSSESR TURTR108740_PE2 NOISO TSADDDNGPGPEER-RGGNSRLGSGEDPTDSTQSTEDGVPRGEDSAQD------TTSESR MATCH CONSENSUS T??D??????????????????????D??D???S?????????????D????????S?S?

AILMEGL192364_1_2_PE1 NOISO DLDHEDEVNSRPERGDSAQESDSEELWVGGGSEGD-SSHGDGSEFGDEEMQNDDPDIIRS BOVIN6_109_PE5 NOISO DLDREDEGNSRPEGGDSTPDSDSEEHWVGGGSEGD-SSHGDGSEFDDEGMQSDDPGAYRS CALJA3_112_PE25 ENSCJAG00000006215 DLDNEDQVDSRPEGGDSTQESESEEHWVGGGSEGE-SSHGDGSEFDDEGMQSDDPDSIRS CALJA3_112_PE26 ISOFORMIN DLDNEDQVDSRPEGGDSTQESESEEHWVGGGSEGE-SSHGDGSEFDDEGMQSDDPDSIRS CALJA3_112_PE27 ISOFORMIN DLDNEDQVDSRPEGGDSTQESESEEHWVGGGSEGE-SSHGDGSEFDDEGMQSDDPDSIRS CALJA3_112_PE28 ISOFORMIN DLDNEDQVDSRPEGGDSTQESESEEHWVGGGSEGE-SSHGDGSEFDDEGMQSDDPDSIRS CAVPO33_2_PE1 NOISO ELDGEDGV-----------DSKSEEHWEGGDSEGD-SSHGTGLEFHDNGMQNDDPDSTRR DASNO27458_PE1 NOISO DLDNGGWVNSRPGGRDATHESESEERWVGGGSEGE-SSHGDASEFDDEGMQSDDPDSIKS DIPOR3670_PE2 NOISO ----SEELNSRLEGGDSTQDSESEETHVGGVSEGE-SSHGDGSEFDDEGMQSDDPDSMKS ERIEU376204_PE1 NOISO DLDSEGEVNSRPGGGSSTQDSESEEQQVGGISDGD-SSHGDGAEFDDEGMQSDDPDSIRS FELCAGS_2911_PE1 NOISO DLDNENEVKSRSEGGGFAQDSESEEHWVGGGSEGD-SSHGDGSEFDDEEMQNDDPDTIRS GORGO4_101_PE3 NOISO ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGE-SSHGDGSKLDDEGMQSDDPDSIRS HORSE3_53_PE4 NOISO DFDNEDEVHSRLEGGHSTQESESEEYWVGGGSEGD-SSHGDGSEFDDEGMQSDDPDTFRS HS4_PE2000 ENSG00000152592 ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGE-SSHGDGSELDDEGMQSDDPESIRS HS4_PE2001 ISOFORMIN ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGE-SSHGDGSELDDEGMQSDDPESIRS LAMPAGS_2384_PE8 NOISO DLDDEGEVNSRPEGGDSTPESESEEHWVGGGSEGE-SSHGDGSEFDDEGMQSDDPGTFRS LOXAF30_8_PE8 NOISO EVDNEGEVNSRPEAGDFTHESESEERWVGGGSEGD-SSHGDGFEFDDEEMQSDDPDSVRS MACEUGS_6036_PE1 NOISO ---RAKKNRMK----VKVHDRDSDEYTVGGGSKQSYSNSRDDSSFDDEEMQGDDADTIGS MACMU5_83_PE10 ENSMMUG00000011114 ELDNEDQVDSRPE-------SDSEEHWVGGVSDGE-SSHGDGSEFDDEGMQSDDPDSIRS MACMU5_83_PE11 ISOFORMIN ELDNEDQVDSRPE-------SDSEEHWVGGVSDGE-SSHGDGSEFDDEGMQSDDPDSIRS MICMUGS_2664_PE1 NOISO ------------------NSSDSEEPWLGGGS------HGEGSESEDTGMQSDDPQGSRS MONDO5_54_PE14 ENSMODG00000020734 SLEEEENESHE----VDVHDSKSDEHNVEVGSEKSYSSSSDESALDEEGMQGDDPDTIMS MONDO5_54_PE15 ISOFORMIN SLEEEENESHE----VDVHDSKSDEHNVEVGSEKSYSSSSDESALDEEGMQGDDPDTIMS MONDO5_54_PE16 ISOFORMIN SLEEEENESHE----VDVHDSKSDEHNVEVGSEKSYSSSSDESALDEEGMQGDDPDTIMS MONDO5_54_PE17 ISOFORMIN SLEEEENESHE----VDVHDSKSDEHNVEVGSEKSYSSSSDESALDEEGMQGDDPDTIMS MOUSE5_PE1652 NOISO DHDSEDEADSRPEAGDSTQDSESEEQRVGGGSEGE-SSHGDGSEFDDEGMQSDDPESTRS ORNANCONTIG263_1_PE12 ENSOANG00000013628 NLDEGEDVSHAADSGASDGDGQS-------RENGE-EHDSDSQEFDDDEMQGDDPDSFGS ORNANCONTIG263_1_PE13 ISOFORMIN NLDEGEDVSHAADSGASDGDGQS-------RENGE-EHDSDSQEFDDDEMQGDDPDSFGS ORNANCONTIG263_1_PE14 ISOFORMIN NLDEGEDVSHAADSGASDGDGQS-------RENGE-EHDSDSQEFDDDEMQGDDPDSFGS ORNANCONTIG263_1_PE15 ISOFORMIN NLDEGEDVSHAADSGASDGDGQS-------RENGE-EHDSDSQEFDDDEMQGDDPDSFGS OTOGAGS_3143_PE1 NOISO DLDN--EVDSRPEGGDSTPDSESEEHWLGVGSDGG-RSHGDGSEFDDEGMQSDDPDSIRS PANTR4_94_PE4 ISOFORMIN ------------------------------------------------GMQSDDPESIRS PANTR4_94_PE5 ENSPTRG00000016262 ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGE-SSHGDGSELDDEGMQSDDPESIRS PANTR4_94_PE6 ISOFORMIN ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGE-SSHGDGSELDDEGMQSDDPESIRS PIG8_115_PE11 NOISO GLDNEDEVDSRPEGGDSTADSESEEPWVGGGSEGE-GSHGDGSEFDDEGMQNDDPGTFRS PONPY4_95_PE3 ENSPPYG00000014917 ELDNEDQEDNRPEGGDSTQESESEEHWVGGGSDGE-SSHGDGSELDDEGMQSDDPDSIRS PONPY4_95_PE4 ISOFORMIN -----------------------------------------------EGMQSDDPDSIRS PTEVA10005_PE2 NOISO DLDNEDDVNSRPEGDDPIQESESEEHWMGGGSDGD-SSHGDGSEFDDEGMQSDDPDTIKS RABIT15_64_PE6 NOISO DLDHEGVVHSRP-------DSESEEHWVGGGSDGE-SSHGDGSEFDDEGMQSDDPDSIMS RAT14_PE127 ENSRNOG00000002167 DHHS-DEADSRPEAGDSTQDSESEEYRVGGGSEGE-SSHGDGSEFDDEGMQSDDPGSTRS RAT14_PE128 ISOFORMIN DHHS-DEADSRPEAGDSTQDSESEEYRVGGGSEGE-SSHGDGSEFDDEGMQSDDPGSTRS SPETRGS_3430_PE1 NOISO DLDHEDDVGSR-EGRDFAQESESEEDWVEC-SEGE-SSHGXXXXXXXXXXXXXXXXXXXX TUPGBGS_3327_PE1 NOISO DLDK-DKVDNRSKGGDLT--SESEEHWD-----GD-SSHGDGSEFHDEGLQSDDPNSIGS TURTR108740_PE2 NOISO DFASEDEGRSRPEGRDSTPDSESAEQWVGGDSEGV-GSHGDGSEFDDEGMQSEDPNTFRS MATCH CONSENSUS ????????????????????S?S?E??????S?G???S??D????DDE?MQ?DDP????S

AILMEGL192364_1_2_PE1 NOISO DRGNSRMNSASVKSEESKGNSDEQ-ASTQDSGDSQSVEYPRRKIFRKSRIS-E-EDDIGE BOVIN6_109_PE5 NOISO ERGNSRISDAGLKSRESKGDDEEQ-ASTQDSHESPAAAYPRRKFFRKSRLP-E-EDGRGE CALJA3_112_PE25 ENSCJAG00000006215 ERGNSRMNSARMKSKESRENS-GQ-ANIRDSGDSQLVEHPSKKNFRKSRIS-E-EDDKGE CALJA3_112_PE26 ISOFORMIN ERGNSRMNSARMKSKESRENS-GQ-ANIRDSGDSQLVEHPSKKNFRKSRIS-E-EDDKGE CALJA3_112_PE27 ISOFORMIN ERGNSRMNSARMKSKESRENS-GQ-ANIRDSGDSQLVEHPSKKNFRKSRIS-E-EDDKGE CALJA3_112_PE28 ISOFORMIN ERGNSRMNSARMKSKESRENS-GQ-ANIRDSGDSQLVEHPSKKNFRKSRIS-E-EDDKGE CAVPO33_2_PE1 NOISO EGGSSRMDSTSVKSKESQGVL-KQ-EGTQDSGDKQSVGSPSRKFFRKSRIS-E-EDDRDD DASNO27458_PE1 NOISO EKSYSRMSSASVKS---KENSDEQ-ASTQDSDDNQSVEYPSRKVFRKSRIS-E-ED---E DIPOR3670_PE2 NOISO ERGHSRISSAGVRSKGSKEVS-EQ-LSPRDSGHILSVEYPSRKFFSKSRIS-E-EDGRHE ERIEU376204_PE1 NOISO ERSHSRVDSASIHSKELRGNSEEH-KGPGDSGHSQSVGHPSRPFPRKSRVS-Q-EDARGE FELCAGS_2911_PE1 NOISO EKGNLRMSSASVE---SKGKSDEQ-ASTQDSVDSQSMEYPRRKIFRKSRIS-E-EDDIGD GORGO4_101_PE3 NOISO ERGNSRMNSAGMKPKESGENS-EQ-ANIQDSGDSQLLEHPSRKIFRKSRIS-E-EDDRSE HORSE3_53_PE4 NOISO ERSNSRMNNASVKSKESKENKDKQ-TSTQDSGESQLVEYPSRKFFRKSRIS-E-EDDRGE HS4_PE2000 ENSG00000152592 ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGGSQLLEHPSRKIFRKSRIS-E-EDDRSE HS4_PE2001 ISOFORMIN ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGGSQLLEHPSRKIFRKSRIS-E-EDDRSE LAMPAGS_2384_PE8 NOISO ERSGSRISSASVKSKELKENDEEQ-ANTQDSHDSQSREFPSRKFFRKSRIS-E-EGGRGD LOXAF30_8_PE8 NOISO DRNNSRMSSASIKSEESKGKSDEQ-ASTQDSDGSQSAENPRRKFFRKSRLS-D-EDDRSE MACEUGS_6036_PE1 NOISO RTSNSRMIRYSVYKEKDSQHKR-PGNRQDSSDGDQLVGQAGRKSFQKAHIS-K-EALWDD MACMU5_83_PE10 ENSMMUG00000011114 ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGDSQLLEHPSRKIFRKSRIS-E-EDDRGE MACMU5_83_PE11 ISOFORMIN ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGDSQLLEHPSRKIFRKSRIS-E-EDDRGE MICMUGS_2664_PE1 NOISO DRGGSRANSPGVTSTGSRRHG----------------E-----RPRKSHLSEE-EDDTGE MONDO5_54_PE14 ENSMODG00000020734 EISNSRMTGHSVNLKKKIHKTRHQDGNRKDSDVSQLVGQFGRKSFQKAHSS-E-EDDWDE MONDO5_54_PE15 ISOFORMIN EISNSRMTGHSVNLKKKIHKTRHQDGNRKDSDVSQLVGQFGRKSFQKAHSS-E-EDDWDE MONDO5_54_PE16 ISOFORMIN EISNSRMTGHSVNLKKKIHKTRHQDGNRKDSDVSQLVGQFGRKSFQKAHSS-E-EDDWDE MONDO5_54_PE17 ISOFORMIN EISNSRMTGHSVNLKKKIHKTRHQDGNRKDSDVSQLVGQFGRKSFQKAHSS-E-EDDWDE MOUSE5_PE1652 NOISO DRGHARMSSAGIRSEESKGDH-EP-TSTQDSDDSQSVEFSSRKSFRRSHVS-E-EDYRGE ORNANCONTIG263_1_PE12 ENSOANG00000013628 DNSNSSMSSDSLNSKESSQENSEQ-GSRQDSNDSQSVGQSSRKWLKKAGISEEEEDDSGE ORNANCONTIG263_1_PE13 ISOFORMIN DNSNSSMSSDSLNSKESSQENSEQ-GSRQDSNDSQSVGQSSRKWLKKAGISEEEEDDSGE ORNANCONTIG263_1_PE14 ISOFORMIN DNSNSSMSSDSLNSKESSQENSEQ-GSRQDSNDSQSVGQSSRKWLKKAGISEEEEDDSGE ORNANCONTIG263_1_PE15 ISOFORMIN DNSNSSMSSDSLNSKESSQENSEQ-GSRQDSNDSQSVGQSSRKWLKKAGISEEEEDDSGE OTOGAGS_3143_PE1 NOISO ERGSSRIKGSTANS--------EQ-PSPEDSGESQ-LGRPGRTAFRKSRLS-P-EAAAP- PANTR4_94_PE4 ISOFORMIN ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGDSQLLEHPSRKIFRKSRIS-Q-EDDRSE PANTR4_94_PE5 ENSPTRG00000016262 ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGDSQLLEHPSRKIFRKSRIS-Q-EDDRSE PANTR4_94_PE6 ISOFORMIN ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGDSQLLEHPSRKIFRKSRIS-Q-EDDRSE PIG8_115_PE11 NOISO EGSNSRISTVNLKSKESKGKDEEK-ASTQDSGESRSVGYASRKFFRKSRIS-E-EGGRGE PONPY4_95_PE3 ENSPPYG00000014917 ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGDSQLLEHPSRKIFRKSRIS-E-EDDRGE PONPY4_95_PE4 ISOFORMIN ERGNSRMNSAGMKSKESGENS-EQ-ANTQDSGDSQLLEHPSRKIFRKSRIS-E-EDDRGE PTEVA10005_PE2 NOISO ERSHSRVNSASVKSKESKENSDEQ-ASPQNSGERQSVEYPGRKFFKNSRIS-V-EDDTGD RABIT15_64_PE6 NOISO ERVKARISSAGVRSKESNGDS-RQ-ASTPDAGQSRSVEYPRRRFFWKSRIS-Q-EDDRHE RAT14_PE127 ENSRNOG00000002167 DRGHTRMSSAGIRSEESKGDH-EP-TSTQDSDDSQDVEFSSRKSFRRSRVS-E-EDDRGE RAT14_PE128 ISOFORMIN DRGHTRMSSAGIRSEESKGDH-EP-TSTQDSDDSQDVEFSSRKSFRRSRVS-E-EDDRGE SPETRGS_3430_PE1 NOISO XXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXX-X-XXXXXX TUPGBGS_3327_PE1 NOISO ERGSSRMLGAGVQSKKSASDA-EQ---GNTQGDSQSSEHPRGKLSRKSRIS-Q-EDDRDE TURTR108740_PE2 NOISO ERSNSRISRASIQSKDSKGSN-GQ-ARTQASGESPAVGYPSRKFFRTSRIS-E-EDGRGE MATCH CONSENSUS ????SR???????S?????????Q?????DS??SQ??????RK?F?K???S???ED???E

AILMEGL192364_1_2_PE1 NOISO LDDNNTME-EIKSDSTENTNSKETGLSQSRENSESESLEESEEKQSP-------EDSQNV BOVIN6_109_PE5 NOISO LDDSRTIE--VMSDSTENPDSKEAGLGQSREHSKSESRQESEENRSP-------EDSQDV CALJA3_112_PE25 ENSCJAG00000006215 LDDNNTME-EVRSDSTENSNSREAGLSQPRRDSKGDSQEDSKENPSQ-------EDSQNL CALJA3_112_PE26 ISOFORMIN LDDNNTME-EVRSDSTENSNSREAGLSQPRRDSKGDSQEDSKENPSQ-------EDSQNL CALJA3_112_PE27 ISOFORMIN LDDNNTME-EVRSDSTENSNSREAGLSQPRRDSKGDSQEDSKENPSQ-------EDSQNL CALJA3_112_PE28 ISOFORMIN LDDNNTME-EVRSDSTENSNSREAGLSQPRRDSKGDSQEDSKENPSQ-------EDSQNL CAVPO33_2_PE1 NOISO LEDSNTVE-DLRSDLTDSTDSQEDSP--GQEDSKSDSQEDTSESQSH-------ED-EDE DASNO27458_PE1 NOISO LDDHNMME-EVMSDSTENSSSKDVSLSQSRENSKGESQEDSEETQSQ-------EDSQNI DIPOR3670_PE2 NOISO LAESRSRE-EVQSDSVGDADSKAAGLSQSREDSQNDSQEDSPQTQSQ-------EDSQDV ERIEU376204_PE1 NOISO LGDADTLEEQVQSHSTESSHSRESGLSQSREDSESDSPEDSQEGQSQ-------EDSQSL FELCAGS_2911_PE1 NOISO LDDSNIME-DVKSDSTENTNSKDAGLSQSRENSKSESLEDSEENQSQ-------EDSQNV GORGO4_101_PE3 NOISO LDDNNTME-EVKSDSTENSNSRDTGLSQPMRDSKGDSQEDSKENLSQ-------EESQNV HORSE3_53_PE4 NOISO LDDNYTME-EVKSDSTENTDSKEAGLRQSRENSKNESQEDSGENQSQ-------EDNENV HS4_PE2000 ENSG00000152592 LDDNNTME-EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ-------EESQNV HS4_PE2001 ISOFORMIN LDDNNTME-EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ-------EESQNV LAMPAGS_2384_PE8 NOISO LDDNYTME-EVQSDSTENPDSKEAGLSQTREHSKSD-KQESEENRSP-------EDSQNA LOXAF30_8_PE8 NOISO LVDSNTME-EFKSDSSENSSSKEIGLSQSRENK-SDSREDSKENQSQ-------EDNQNV MACEUGS_6036_PE1 NOISO NNESNTME-EAMSDSKENSNPMKTENSQSHENSQSKSQEDSN-SQSQ-------ESS--- MACMU5_83_PE10 ENSMMUG00000011114 FDDNNTME-EVKSDSTENSNSRDAGLGQPRRDSKGDSQEDSKENMSQ-------EDSQKV MACMU5_83_PE11 ISOFORMIN FDDNNTME-EVKSDSTENSNSRDAGLGQPRRDSKGDSQEDSKENMSQ-------EDSQKV MICMUGS_2664_PE1 NOISO PDGGHTVE-VAQSDSTENRDSKSG-PVQARED--SQSQEAREDSQSR-------EDSHHT MONDO5_54_PE14 ENSMODG00000020734 NNESNTME-ETMSDSTEKRQ--SSENGQSNENSKSKSQEDSN-SQSQ-------EDSQTV MONDO5_54_PE15 ISOFORMIN NNESNTME-ETMSDSTEKRQ--SSENGQSNENSKSKSQEDSN-SQSQ-------EDSQTV MONDO5_54_PE16 ISOFORMIN NNESNTME-ETMSDSTEKRQ--SSENGQSNENSKSKSQEDSN-SQSQ-------EDSQTV MONDO5_54_PE17 ISOFORMIN NNESNTME-ETMSDSTEKRQ--SSENGQSNENSKSKSQEDSN-SQSQ-------EDSQTV MOUSE5_PE1652 NOISO LTDSNSRE-T-QSDSTEDTAS--------KEESRSESQEDTAESQSQ-------EDSPEG ORNANCONTIG263_1_PE12 ENSOANG00000013628 QNDSNSME-ERDSHSTEDSSSREASPGQSEENSKSKSHEDSGSRSREGADSRGSRDLSSS ORNANCONTIG263_1_PE13 ISOFORMIN QNDSNSME-ERDSHSTEDSSSREASPGQSEENSKSKSHEDSGSRSREGADSRGSRDLSSS ORNANCONTIG263_1_PE14 ISOFORMIN QNDSNSME-ERDSHSTEDSSSREASPGQSE----------------EGADSRGSRDLSSS ORNANCONTIG263_1_PE15 ISOFORMIN QNDSNSME-ERDSHSTEDSSSREASPGQSE----------------EGADSRGSRDLSSS OTOGAGS_3143_PE1 NOISO --------EEMQSDSAEDADAREAGLRRSREDSRHESQEDREENESW-------EDSRNE PANTR4_94_PE4 ISOFORMIN LDDNNTME-EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ-------EESQNV PANTR4_94_PE5 ENSPTRG00000016262 LDDNNTME-EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ-------EESQNV PANTR4_94_PE6 ISOFORMIN LDDNNTME-EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ-------EESQNV PIG8_115_PE11 NOISO LEDENMME-V-K------SDSAEAHLSQSWEHRRRESQQESEENESP-------EEGQHV PONPY4_95_PE3 ENSPPYG00000014917 LDDNNTME-EVKSDSTENSNSRDTGLSQPRRDSKGDSQENSKENLSQ-------EDSQNV PONPY4_95_PE4 ISOFORMIN LDDNNTME-EVKSDSTENSNSRDTGLSQPRRDSKGDSQENSKENLSQ-------EDSQNV PTEVA10005_PE2 NOISO LDNSNTME-EVKSDSRENTNSKEVGLSQSRENSKSESQEDNEEIQSQ-------KDSQNV RABIT15_64_PE6 NOISO LEDSNTQE-EV-EDSTESPDSRDAGLSRSRED--------SRESQSQ-------EDSNNE RAT14_PE127 ENSRNOG00000002167 LADSNSRE-T-QSDSTEDFRS--------KEESRSETQEDTAETQSQ-------EDSPEG RAT14_PE128 ISOFORMIN LADSNSRE-T-QSDSTEDFRS--------KEESRSETQEDTAETQSQ-------EDSPEG SPETRGS_3430_PE1 NOISO XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXKSESQED-SMSRSQ-------EDCVNA TUPGBGS_3327_PE1 NOISO LDDSNTVE-EVQSDSTEDAISKEASRGQSRERSDSESPEDSPETLSK-------EDGHHA TURTR108740_PE2 NOISO LHDSNTME-ESKSDSPEYPDSKEAGLSPSREHSESESQQESEEGQSP-------EDSQSV MATCH .. CONSENSUS ????N??E????SDSTE???S??????Q????S???S?E??????S????????ED????

AILMEGL192364_1_2_PE1 NOISO QDPSSESSQEIDQPSQENSSESQEEVV-SESRGDNPDN-TTSHSE-----DQEDSDSSEE BOVIN6_109_PE5 NOISO QDPSSESSQEVDLPSQENSSESQEEAL-HESRGDNPDN-ATSHSR----EHQADNESSEE CALJA3_112_PE25 ENSCJAG00000006215 DGPSSESSQEADLPSQENSSESQEEVV-SEPRGDNPDPT-TSY-V----EDQEDSDSSEE CALJA3_112_PE26 ISOFORMIN DGPSSESSQEADLPSQENSSESQEEVV-SEPRGDNPDPT-TSY-V----EDQEDSDSSEE CALJA3_112_PE27 ISOFORMIN DGPSSESSQEADLPSQENSSESQEEVV-SEPRGDNPDPT-TSY-V----EDQEDSDSSEE CALJA3_112_PE28 ISOFORMIN DGPSSESSQEADLPSQENSSESQEEVV-SEPRGDNPDPT-TSY-V----EDQEDSDSSEE CAVPO33_2_PE1 NOISO QDTSSESSQEVDTPSQESSSESQEEVMAAESRGDNPDAT-----------SQPDSDSSEE DASNO27458_PE1 NOISO PDLSSESSQEVDLPSQENSSESQEVVE-SESRGDNPDQTAI---E----EDQGDSDSNEE DIPOR3670_PE2 NOISO QDSSSESSQEDDLPSQESSSESQEEVV-NESRGDNPDYTS----Q----TEQRDSNSSEE ERIEU376204_PE1 NOISO PNSSSESSQEGDPPSQESSSEFQEGTV-SESRGDSPDGSHS--------EGRDKSQSSEE FELCAGS_2911_PE1 NOISO QDPSSESSQEVDLPSQENSSESQEDVV-SESRGDNPDN-TTSYSE-----DQEDSDSSEE GORGO4_101_PE3 NOISO DGPSSESSQEVNLSSQENSSESQEEVV-SESRGDNPDPT-TSY-V----EDQEDSDSSEE HORSE3_53_PE4 NOISO QDPSNESIQEDDPPSQENSSESQEEIV-SESRGDNPDN-TTSHSE----EDQEDSDSSEE HS4_PE2000 ENSG00000152592 DGPSSESSQEANLSSQENSSESQEEVV-SESRGDNPDPT-TSY-V----EDQEDSDSSEE HS4_PE2001 ISOFORMIN DGPSSESSQEANLSSQENSSESQEEVV-SESRGDNPDPT-TSY-V----EDQEDSDSSEE LAMPAGS_2384_PE8 NOISO QDPSSESSEEVDLPSQESSSESQEEVA-GEPRGDNPDN-ITSPSE----ENQEESDSSEE LOXAF30_8_PE8 NOISO QDLSSESSQEADLPPQENSSESQEEVV-SESRGDNPDQNTTNHSE----EDQEDSDSSEE MACEUGS_6036_PE1 NOISO QNLSRESRPHNDDDSREKQSKSQEENE-NVSRGDNSASNRKSVGLSEVNNEDTSSNSSEE MACMU5_83_PE10 ENSMMUG00000011114 DSPSSESSQEGNLPSQENSSESQQEVV-SESRGDNPDPT-TSH-V----EDQEDSDSSEE MACMU5_83_PE11 ISOFORMIN DSPSSESSQEGNLPSQENSSESQQEVV-SESRGDNPDPT-TSH-V----EDQEDSDSSEE MICMUGS_2664_PE1 NOISO PEPSSESSPEADTSS---SSESQEEAA-TESRGDNPDDTESHAEDR---GDSDSSESSEE MONDO5_54_PE14 ENSMODG00000020734 RDLSSESRPHDSDESYEKQSKSKEENE-NVSRGDNPDSDGKSVGLSEDNKEDSS-NSSEE MONDO5_54_PE15 ISOFORMIN RDLSSESRPHDSDESYEKQSKSKEENE-NVSRGDNPDSDGKSVGLSEDNKEDSS-NSSEE MONDO5_54_PE16 ISOFORMIN RDLSSESRPHDSDESYEKQSKSKEENE-NVSRGDNPDSDGKSVGLSEDNKEDSS-NSSEE MONDO5_54_PE17 ISOFORMIN RDLSSESRPHDSDESYEKQSKSKEENE-NVSRGDNPDSDGKSVGLSEDNKEDSS-NSSEE MOUSE5_PE1652 NOISO QDPSSESSEEAGEPSQESSSESQEGVT-SESRGDNPDNTSQ---A----GDQEDSESSEE ORNANCONTIG263_1_PE12 ENSOANG00000013628 KDHSKGSSQETVLKQK--SSKSHEDSE-VTSRGDNPEPNED--------GDEVDSDSSQE ORNANCONTIG263_1_PE13 ISOFORMIN KDHSKGSSQETVLKQK--SSKSHEDSE-VTSRGDNPEPNED--------GDEVDSDSSQE ORNANCONTIG263_1_PE14 ISOFORMIN KDHSKGSSQETVLKQK--SSKSHEDSE-VTSRGDNPEPNED--------GDEVDSDSSQE ORNANCONTIG263_1_PE15 ISOFORMIN KDHSKGSSQETVLKQK--SSKSHEDSE-VTSRGDNPEPNED--------GDEVDSDSSQE OTOGAGS_3143_PE1 NOISO PEPSSESSQEADLPSEESSSESREAA--GESRGDNPDDVA-------------NRDSSEE PANTR4_94_PE4 ISOFORMIN DGPSSESSQEVNLSSQENSSESQEEVV-SESRGDNPNPT-TSY-A----EDQEDSDSSEE PANTR4_94_PE5 ENSPTRG00000016262 DGPSSESSQEVNLSSQENSSESQEEVV-SESRGDNPNPT-TSY-A----EDQEDSDSSEE PANTR4_94_PE6 ISOFORMIN DGPSSESSQEVNLSSQENSSESQEEVV-SESRGDNPNPT-TSY-A----EDQEDSDSSEE PIG8_115_PE11 NOISO QDLSSESSQEVDLPSQENSSESQEEGV-GEPRGDNPDN-ITSHSK----EDLEESDSS-E PONPY4_95_PE3 ENSPPYG00000014917 DGPSSESSQEVNLSSQENSSESQEEVV-SESRGDNPDPP-TSH-V----EDQEDSDSSEE PONPY4_95_PE4 ISOFORMIN DGPSSESSQEVNLSSQENSSESQEEVV-SESRGDNPDPP-TSH-V----EDQEDSDSSEE PTEVA10005_PE2 NOISO QDPSSESSQELDLPSQETSSESQEEVV-SKSRGDNPDD-TSSHSE----EGQEDSDSSEE RABIT15_64_PE6 NOISO QDPSSESSQEADLPSQESSSESQEEGL-SESRGDNPDATTSS--------TEEDSDSSQE RAT14_PE127 ENSRNOG00000002167 QDPSSESSEEAGEPSQESSSESQEGVA-SESRGDNPDNTSQ---T----GDQRDSESSEE RAT14_PE128 ISOFORMIN QDPSSESSEEAGEPSQESSSESQEGVA-SESRGDNPDNTSQ---T----GDQRDSESSEE SPETRGS_3430_PE1 NOISO QDNSSESTQEADLASQDCSSESEEEVA-RECRGDNPDNLTRSS-------DQEDSDCS-Q TUPGBGS_3327_PE1 NOISO QDLSSESSQEGDLLSRESSSESQEEVV-SESRGDNPDNTT-GHS-----EGKDNSESSEE TURTR108740_PE2 NOISO QDPSSESSEEGDLPSQESSSESQEEVV-RESRGDNPNN-VTSHSE----D-QDSSDSSDE MATCH * * . .*: .: ***.. . :.. : CONSENSUS ???SSESS?E????S?E?SS?S?E??????SRGDNP??????????????????S?SSEE

AILMEGL192364_1_2_PE1 NOISO NSLNKTSSSESESTEEQADSESNESLKDS--EESPEFTE-ENSSSQEG-LQSHSASAE-S BOVIN6_109_PE5 NOISO DVLDKPSDSESTSTEEQADSESHESLRSS--EESPESTEEQNSSSQEG-AQ--T------ CALJA3_112_PE25 ENSCJAG00000006215 DSLHTLSHSESESREEQADSESSESLNSS--EESPESPEDENSSSQEG-LQSHSSSAE-S CALJA3_112_PE26 ISOFORMIN DSLHTLSHSESESREEQADSESSESLNSS--EESPESPEDENSSSQEG-LQSHSSSAE-S CALJA3_112_PE27 ISOFORMIN DSLHTLSHSESESREEQADSESSESLNSS--EESPESPEDENSSSQEG-LQSHSSSAE-S CALJA3_112_PE28 ISOFORMIN DSLHTLSHSESESREEQADSESSESLNSS--EESPESPEDENSSSQEG-LQSHSSSAE-S CAVPO33_2_PE1 NOISO DSLNTFSSSESESREQQADSESNESLRLS--EESQESSEDDHSSSQED-LQSWSTSTE-S DASNO27458_PE1 NOISO ENSNKSSNSESESKEEQADSESNESLNSS--KESPETTEDENSSSQEG-LQSESASAE-S DIPOR3670_PE2 NOISO ESFHTFSSSESESREEQADSESI-------SEESPESSEDDNSSSQEG-LQSQSASAE-S ERIEU376204_PE1 NOISO DNLNLPSDSKSWSREEPANSDSNETLRDS--KDSSESTGVDSSSSQES-LQSHSASNE-S FELCAGS_2911_PE1 NOISO NSLNNPSSSESESREEQADSESNESLNDSESKESPESTEDENSSSQEG-LQSHSASAE-S GORGO4_101_PE3 NOISO DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSSSAE-S HORSE3_53_PE4 NOISO DSLNKPSNSESKSREEQADSESNESLKYS--EESPESSEEKNSSSQEG-LQSHSASTE-S HS4_PE2000 ENSG00000152592 DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSSSAE-S HS4_PE2001 ISOFORMIN DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSSSAE-S LAMPAGS_2384_PE8 NOISO NSLDKPSNSESKSREEQADSESNESLNSE--E-SSETTEEENSSSQEG-LQ--SDSAS-A LOXAF30_8_PE8 NOISO DNVSKPSNSESESREEQADSDSNESLKSS--EESPESVEDENSSSQES-LQSQSASTE-S MACEUGS_6036_PE1 NOISO SNLTTSSKSNSESREDQDS-KSHESVNTS--EESKESIEDEDSSSQEG-FQSQSSSRV-S MACMU5_83_PE10 ENSMMUG00000011114 DSSHTLSHSKSESREEQADSKSSESLSFS--EESPESPEDENSSSQEG-LQSHSTSTE-S MACMU5_83_PE11 ISOFORMIN DSSHTLSHSKSESREEQADSKSSESLSFS--EESPESPEDENSSSQEG-LQSHSTSTE-S MICMUGS_2664_PE1 NOISO GGATVPSSSESESSESLASASSSSSSSSS---ESPESPPGDEDSS--------------- MONDO5_54_PE14 ENSMODG00000020734 DDLNTSSKSDSESGEAQSDSESNESESPS--VESKE-SSEENSSNQEG-FQSQSSSTE-S MONDO5_54_PE15 ISOFORMIN DDLNTSSKSDSESGEAQSDSESNESESPS--VESKE-SSEENSSNQEG-FQSQSSSTE-S MONDO5_54_PE16 ISOFORMIN DDLNTSSKSDSESGEAQSDSESNESESPS--VESKE-SSEENSSNQEG-FQSQSSSTE-S MONDO5_54_PE17 ISOFORMIN DDLNTSSKSDSESGEAQSDSESNESESPS--VESKE-SSEENSSNQEG-FQSQSSSTE-S MOUSE5_PE1652 NOISO DSLNTFSSSESQSTEEQADSESNESLSLS--EESQESAQDGDSSSQEG-LQSQSASTE-S ORNANCONTIG263_1_PE12 ENSOANG00000013628 SSLSKSSQSESESRESQEHSKSSESSRQS--EESRESSEEKSSSSHEG-LLSHSRSSSKE ORNANCONTIG263_1_PE13 ISOFORMIN SSLSKSSQSESESRESQEHSKSSESSRQS--EESRESSEEKSSSSHEG-LLSHSRSSS-- ORNANCONTIG263_1_PE14 ISOFORMIN SSLSKSSQSESESRESQEHSKSSESSRQS--EESRESSEEKSSSSHEG-LLSHSRSSSKE ORNANCONTIG263_1_PE15 ISOFORMIN SSLSKSSQSESESRESQEHSKSSESSRQS--EESRESSEEKSSSSHEG-LLSHSRSSSKE OTOGAGS_3143_PE1 NOISO GGLTASSQFRSESGEDQADGESSESLQSS--EESPESAEEGNSSSQEG-FRSHSASAE-S PANTR4_94_PE4 ISOFORMIN DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSSSAE-S PANTR4_94_PE5 ENSPTRG00000016262 DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSSSAE-S PANTR4_94_PE6 ISOFORMIN DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSSSAE-S PIG8_115_PE11 NOISO ESLDKPSNSESQSREDPADAESKESLLSS--EESPESTEEENSSSQEEGLQAHSPSAE-T PONPY4_95_PE3 ENSPPYG00000014917 DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSTSAE-S PONPY4_95_PE4 ISOFORMIN DSSHTLSHSKSESREEQADSESSESLNFS--EESPESPEDENSSSQEG-LQSHSTSAE-S PTEVA10005_PE2 NOISO GSLSKPSSSESKSQEEQADSESNESLKYS--EESPESTEEENSSSQEG-LQSHSASAE-S RABIT15_64_PE6 NOISO DNLSVPSSSESQSREEQADSDSNESLKSS--EESPETTEEENSSSQEG-LQSQSESAE-S RAT14_PE127 ENSRNOG00000002167 DRLNTFSSSESQSTEEQGDSESNESLSLS--EESQESAQDEDSSSQEG-LQSQSASRE-S RAT14_PE128 ISOFORMIN DRLNTFSSSESQSTEEQGDSESNESLSLS--EESQESAQDEDSSSQEG-LQSQSASRE-S SPETRGS_3430_PE1 NOISO HSLNTFSISVSVSREEQADSESNESLKLS--ENFPESPEVEKSSSQER-LESPSFSAQ-T TUPGBGS_3327_PE1 NOISO NSQNTSSTSESQSREEHADSESNESLRSS--EESPESTEEENSSSQES-LESRSNSAE-S TURTR108740_PE2 NOISO DSSDKPSSSESRSTEGQTDSESSESLRSS--EESPESTEEENSSSQED-PW--SPSAS-S MATCH * * * * .* * .*. CONSENSUS ??????S?S?S?S?E?Q?DS?S?ES???S??EES?ES?????SSSQEG???S?S?S????

AILMEGL192364_1_2_PE1 NOISO QSE------ESQSE---QDSQSEEDDASDS-QDSSKSKED-SNSTESKSSSEED-GQSKN BOVIN6_109_PE5 NOISO QSR------S-------QESPSEEDDGSDS-QDSSRSKED-SNSTESVSSSEEE-AQTKN CALJA3_112_PE25 ENSCJAG00000006215 QSE------ESQS----------EEDDSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN CALJA3_112_PE26 ISOFORMIN QSE------ESQS----------EEDDSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN CALJA3_112_PE27 ISOFORMIN QSE------ESQS----------EEDDSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN CALJA3_112_PE28 ISOFORMIN QSE------ESQS----------EEDDSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN CAVPO33_2_PE1 NOISO QSQ------ESSSR---------EDTDSNS-QDASWSKED-SNSTESTSSSEED-WLPKN DASNO27458_PE1 NOISO PSK------ESQS----------EDDESDS-QDSSK------------------------ DIPOR3670_PE2 NOISO QSP------ESQS---------EEEADSDS-QDSSRSQE--SSSRESTSSSEED-GQPKN ERIEU376204_PE1 NOISO QSD------ESRSV---QDGE----DGSDSRNSGSQSQED-SSSTESTSSSEEE-GQSKM FELCAGS_2911_PE1 NOISO ESK------ESQS---------EEDDVSDS-QDSSKSKED-SNSTESKSSSEED-GQSKN GORGO4_101_PE3 NOISO QSE------ESHS----------EEDDSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN HORSE3_53_PE4 NOISO QSE------ESQSE---QNSQSEEEDGSDS-QD--------------------------- HS4_PE2000 ENSG00000152592 QSE------ESHS----------EEDDSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN HS4_PE2001 ISOFORMIN QSE------ESHS----------EEDDSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN LAMPAGS_2384_PE8 NOISO ETK------S-------QESQSEEDDGSDS-QDSSISQEE-SNSPESVSSSEED-GQSKT LOXAF30_8_PE8 NOISO QSE------ESQSE---QDSQSVEDDDSDS-QDSSRSKED-SNSTESKSSSEED-GQSKN MACEUGS_6036_PE1 NOISO -----------------QSGESQSEDDARAFQENSNLKED-VNSNESPSVSNEE-SLSRS MACMU5_83_PE10 ENSMMUG00000011114 QSE------ESQS----------EEDDSDS-QDSSRSKED-SNSTESESSSEED-GQLKN MACMU5_83_PE11 ISOFORMIN QSE------ESQS----------EEDDSDS-QDSSRSKED-SNSTESESSSEED-GQLKN MICMUGS_2664_PE1 NOISO ------------------------SRDSDSRDSSSPSGEDGDSTAESRSSSEED-GRPRT MONDO5_54_PE14 ENSMODG00000020734 QSVSKEDSGESSSEQLQEEENSQSEEDARALQENSKLKEN-ESSSESRSVSNEE-SLSRS MONDO5_54_PE15 ISOFORMIN QSVSKEDSGESSSEQLQEEENSQSEEDARALQENSKLKEN-ESSSESRSVSNEE-SLSRS MONDO5_54_PE16 ISOFORMIN QS---------------------SEEDARALQENSKLKEN-ESSSESRSVSNEE-SLSRS MONDO5_54_PE17 ISOFORMIN QSVSKEDSGESSSEQLQEEEN--------TLQENSKLKEN-ESSSESRSVSNEE-SLSRS MOUSE5_PE1652 NOISO RSQ------ESQSE---QDSRSEE--DSDS-QDSSRSKEE-SNSTGSASSSEED-IRPKN ORNANCONTIG263_1_PE12 ENSOANG00000013628 DSA------ESSSE---QVGTKESDSEESESQENSTSKRD-SKSTESQSSSEEDASLSKS ORNANCONTIG263_1_PE13 ISOFORMIN -------------K---EVGTKESDSEESESQENSTSKRD-SKSTESQSSSEEDASLSKS ORNANCONTIG263_1_PE14 ISOFORMIN DSA------ESSSE---QVGTKESDSEESESQENSTSKRD-SKSTESQSSSEEDASLSKS ORNANCONTIG263_1_PE15 ISOFORMIN DSA------ESSSE---QVGTKESDSEESESQENSTSKRD-SKSTESQSSSEEDASLSKS OTOGAGS_3143_PE1 NOISO QSE------E--------------DRSSDS-QDSSRSKED-SDSTESTSSSEEH-GQSKT PANTR4_94_PE4 ISOFORMIN QSE------ESHS----------EEDNSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN PANTR4_94_PE5 ENSPTRG00000016262 QSE------ESHS----------EEDNSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN PANTR4_94_PE6 ISOFORMIN QSE------ESHS----------EEDNSDS-QDSSRSKED-SNSTESKSSSEED-GQLKN PIG8_115_PE11 NOISO QSQ------ESQSE---QDSPSEEDDASDS-QDSSKSK-E-SNSTESTSSSEEE-GQAKA PONPY4_95_PE3 ENSPPYG00000014917 QSE------ESHS----------EEDDSDS-QDSSRSKED-SSSTESKSSSEED-GQLKN PONPY4_95_PE4 ISOFORMIN QSE------ESHS----------EEDDSDS-QDSSRSKED-SSSTESKSSSEED-GQLKN PTEVA10005_PE2 NOISO QSE------ESQS---------EEDDSSDS-QDSSKSQED-SNSTESKSSSEED-GQSKN RABIT15_64_PE6 NOISO PSE------ESQSE---QDSQSDEGAGSDS-QENSKSKED-SNSTESMSSSEED-GQARG RAT14_PE127 ENSRNOG00000002167 RSQ------ESQSE---QDSRSEENRDSDS-QDSSRSKEE-SNSTGSTSSSEED-NHPKN RAT14_PE128 ISOFORMIN RSQ------ESQSE---QDSRSEENRDSDS-QDSSRSKEE-SNSTGSTSSSEED-NHPKN SPETRGS_3430_PE1 NOISO QSD------QSHT---------EDERDSDS-QYSSRSKED-SNSTESTSSSEED-GQPKN TUPGBGS_3327_PE1 NOISO QSQ------ESQXX---XXXXXXXXXXXXX--------XX-XXXXXXXXXXXXX-XXXXX TURTR108740_PE2 NOISO DSQ------SRESQ---EDSPSEEEQSSDS-QDSSRSKEE-SNSTESTSSSEED-IQSRN MATCH CONSENSUS ?S???????ES????????????????????Q??S?SKE????S?ES?SSSEE???????

AILMEGL192364_1_2_PE1 NOISO TEIESRKLTVDTYHNKPIGDQDDNDCQDGY BOVIN6_109_PE5 NOISO TEVESRKLTVDAYHNKPIGDQDDNDCQDGY CALJA3_112_PE25 ENSCJAG00000006215 IEIESRKLTVDAYHNKPIGDQDDNDCQDGY CALJA3_112_PE26 ISOFORMIN IEIESRKLTVDAYHNKPIGDQDDNDCQDGY CALJA3_112_PE27 ISOFORMIN IEIESRKLTVDAYHNKPIGDQDDNDCQDGY CALJA3_112_PE28 ISOFORMIN IEIESRKLTVDAYHNKPIGDQDDNDCQDGY CAVPO33_2_PE1 NOISO MEAESRKLTVDLYHNKPIGDQDDNDCQDGY DASNO27458_PE1 NOISO ------------------------------ DIPOR3670_PE2 NOISO MEADSRKLTVDTYHNKPIGDQDDNDCQDGY ERIEU376204_PE1 NOISO AERESRKLTADAQHNKPTGDQDDNDCQDGY FELCAGS_2911_PE1 NOISO TEIESRKLTVDAYHNKPIGDQDDNDCQDGY GORGO4_101_PE3 NOISO IEIESRKLTVDAYHNKPIGDQDDNDCQDGY HORSE3_53_PE4 NOISO ------------------------------ HS4_PE2000 ENSG00000152592 IEIESRKLTVDAYHNKPIGDQDDNDCQDGY HS4_PE2001 ISOFORMIN IEIESRKLTVDAYHNKPIGDQDDNDCQDGY LAMPAGS_2384_PE8 NOISO TEIDGRKLTVDAYHNKPIGDQDDNDCQDGY LOXAF30_8_PE8 NOISO TEIESRKLTVDIYHNKPIGDQDDNDCQDGY MACEUGS_6036_PE1 NOISO IEVESRKLVLDSYHNRPTGDRDDNDCQDGY MACMU5_83_PE10 ENSMMUG00000011114 IEIESRKLTVDAYHNKPIGEQDDNDCQDGY MACMU5_83_PE11 ISOFORMIN IEIESRKLTVDAYHNKPIGEQDDNDCQDGY MICMUGS_2664_PE1 NOISO VEIESRKL-VDAYHNKLIGDQDD-NCQDGY MONDO5_54_PE14 ENSMODG00000020734 IEVESRKLIVDTYHNRPTGDHDDNDCQDGY MONDO5_54_PE15 ISOFORMIN IEVESRKLIVDTYHNRPTGDHDDNDCQDGY MONDO5_54_PE16 ISOFORMIN IEVESRKLIVDTYHNRPTGDHDDNDCQDGY MONDO5_54_PE17 ISOFORMIN IEVESRKLIVDTYHNRPTGDHDDNDCQDGY MOUSE5_PE1652 NOISO MEADSRKLIVDAYHNKPIGDQDDNDCQDGY ORNANCONTIG263_1_PE12 ENSOANG00000013628 IELESRKLMLDAYHNKPIGDHDDNDCQDGY ORNANCONTIG263_1_PE13 ISOFORMIN IELESRKLMLDAYHNKPIGDHDDNDCQDGY ORNANCONTIG263_1_PE14 ISOFORMIN IELESRKLMLDAYHNKPIGDHDDNDCQDGY ORNANCONTIG263_1_PE15 ISOFORMIN IELESRKLMLDAYHNKPIGDHDDNDCQDGY OTOGAGS_3143_PE1 NOISO VEIESRKLTVDAYHNKPIGDQDDNDCQDGY PANTR4_94_PE4 ISOFORMIN IETESRKLTVDAYHNKPIGDQD-------- PANTR4_94_PE5 ENSPTRG00000016262 IETESRKLTVDAYHNKPIGDQDDNDCQDGY PANTR4_94_PE6 ISOFORMIN IETESRKLTVDAYHNKPIGDQDDNDCQDGY PIG8_115_PE11 NOISO TEIESRKLTVDAYHNRPMGDQDDNDCQDGY PONPY4_95_PE3 ENSPPYG00000014917 IEIESRKLTVDAYHNKPIGDQDDNDCQDGY PONPY4_95_PE4 ISOFORMIN IEIESRKLTVDAYHNKPIGDQD-------- PTEVA10005_PE2 NOISO TEIESRKLTVDAYHNKPIGDQDDNDCQDGY RABIT15_64_PE6 NOISO MDMESRKLTVDTYNNKPIGDQDDNDCQDGY RAT14_PE127 ENSRNOG00000002167 IEADNRKLIVDAYHNKPIGDQDDNDCQDGY RAT14_PE128 ISOFORMIN IEADNRKLIVDAYHNKPIGDQDDNDCQDGY SPETRGS_3430_PE1 NOISO MEMDSRKLTVDAYHNKPIGDQDDNDCQDGY TUPGBGS_3327_PE1 NOISO XEIESRKLPVYTYHN-PIGDQDDNDCQDGY TURTR108740_PE2 NOISO TEIESRRLTVDAYHNKPIGDQDDNDCQDGY MATCH CONSENSUS ?E?ESRKL?VD?YHN?P?GD?DDNDCQDGY


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