Alignment of the gene Family HOG000230542 of HOGENOM

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ACYPI_15750_PE7 NOISO -----------------------------------------MRLNIRTL-FLVLSSLIIV AEDAE_380_PE3 NOISO ----------------------------------------MMRLNLKFL-LVCLCFAVFL AILMEGL192768_1_2_PE4 ENSAMEG00000014172 ------------------------------------MRCLAARVNYKT--LIIICTLFTL ANOCA1094_PE3 NOISO ------------------------------------MRCLAARINYKT--LIVICVLFTL ANOGA_1_PE1164 AGAP005699 -----------------------------------------MRLNLKFL-LISLCVTVAL APIME_525_PE10 NOISO ----------------------------------------MMRLNFKTV-LLVIVVAVLS BOVIN10_17_PE5 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL CABRI1_3_PE1525 NOISO ------------------------------------MKCWRWRSNRHRIYLFFACASLLL CAEELIII_PE1087 NOISO ------------------------------------MKCLRWRSNRHRIYLLVACGALFL CALJA10_13_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL CANFA30_38_PE2 NOISO ------------------------------------MRCLAARVNYKT--LIIICTLFTL CAVPO0_90_PE6 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFTL CHICK10_PE537 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL CHOHO23339_PE1 NOISO ------------------------------------------------------------ CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 ------------------------------------VRNVLFLRKYVL--LLFGCSSLVL CULQU_2638_PE9 NOISO ----------------------------------------MMRLNLKFL-LICLCFAVFL DANRE25_9_PE30 NOISO ------------------------------------MRCLVARINHKT--LIVICAVFAL DANRE7_36_PE10 ENSDARG00000068981 -----------------------------------MMRCLAARVHYKT--LIVICALLSL DROME2R_3_PE54 FBGN0033087 SKYLSSQRDALSAPALPVSRENREPPKFQG--QREPLVFFIMRLNLKAV-LLVLTVAVVV ECHTE200238_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFTL FUGRU1_4_PE32 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL GASACGROUPII_20_PE8 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFTL GORGO15_52_PE3 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL HORSE1_129_PE4 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL HS15_PE1022 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL LAMPAGS_1629_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFSL LOXAF28_1_PE9 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL MACMU7_50_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL MICMUGS_2127_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL MONDO1_161_PE3 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFTL MOUSE9_PE1247 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL MYOLUGS_2764_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL NEMVE_415_PE90 NOISO ------------------------------------------------------------ OCHPR5803_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFTL ORNANCONTIG102_1_PE6 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFTL ORYLA3_11_PE11 NOISO ------------------------------------MRCLAARVNYKT--LIFICALFTL PANTR15_71_PE4 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL PIG1_179_PE2 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL POEGU10RD_PE15 NOISO ------------------------------------------------------------ PONPY15_69_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL PRIPA_2470_PE4 NOISO ------------------------------------------------------------ PTEVA2316_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFIL RABITUN0095_1_PE3 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL RAT8_PE934 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL SORAR240806_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL SPETRGS_2734_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL TARSY6414_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIIICAFFTL TETNG5_PE548 NOISO ------------------------------------MRCLAARVNYKT--LIIICALFTL TRIAD_1257_PE623 NOISO -------------------------------------------------------MLFLL TUPGBGS_2674_PE1 NOISO ------------------------------------MRCLAARVSYKT--LIIICALFTL TURTR91481_PE1 NOISO ------------------------------------MRCLAARVNYKT--LIVICALFTL XENTR40_1_PE17 NOISO ------------------------------------MRCLAARVNYKT--LIFICSLFTL MATCH CONSENSUS ????????????????????????????????????MRCLAARVNYKT??LI?ICALFTL

ACYPI_15750_PE7 NOISO CTLSLWSNCSNQTFDTFSTNIKP------------------------------------- AEDAE_380_PE3 NOISO ITFTLWTNCGSDLP--FARGLVP------------------------------------- AILMEGL192768_1_2_PE4 ENSAMEG00000014172 VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKRAAA-SESNN----YVNHMAK-QSE ANOCA1094_PE3 NOISO VTVLLWNRCSNGQAGS-FLRGGGGVGGFRAEGPEKRAAPSESIAGREGDGGPAAGRAQSE ANOGA_1_PE1164 AGAP005699 ITFALWANCGVG------HGFVP------------------------------------- APIME_525_PE10 NOISO SILTSWNNCGSPSF--FKNT---------------------------------------- BOVIN10_17_PE5 NOISO VTVLLWNKCSSDKAIQ-VPRHLS--SGFRVDALEKKAAA-SESNN----YVNHMAK-QSE CABRI1_3_PE1525 NOISO LSKHYLTVTVPIDEEDEELNPV-------------------------------------- CAEELIII_PE1087 NOISO LNRHLTQEESRIDEEDEELTQV-------------------------------------- CALJA10_13_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKRAA-ASESNS----YANHMAKQQSE CANFA30_38_PE2 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKRAAA-SESNH----YVNHMAK-QSE CAVPO0_90_PE6 NOISO VTVLLWNKCSSDRAIQ-FPRHLN--SGFRVDGLEKRA-AASESNH----YLNHGARQHSE CHICK10_PE537 NOISO VTVLLWNRCSSDGSGP-FPRSPA--GP------ERRAAAASN--G-----PARDVGKQSE CHOHO23339_PE1 NOISO ---------------------------------LEKRAAASESNN----YVNHLARQQSE CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 VFIMLQNTEKELCDNQHIVTKNAALSSDKLAEL--------------------------K CULQU_2638_PE9 NOISO ITFTLWTNCGGDLP--FARGLVP------------------------------------- DANRE25_9_PE30 NOISO ITILLWNKCSSDKDLPSPVRPLE-FAAP---TP------------------------EKE DANRE7_36_PE10 ENSDARG00000068981 LTVLLWNKCTSEKALRFLPRHPQPPPSPKID----------------------------S DROME2R_3_PE54 FBGN0033087 ITLGVYMRCAA-FS--FSPDFVR------------------------------------- ECHTE200238_PE1 NOISO VTVLLWNKCSSDRPIQ-FPRHLS--GGFR-DGLEKRA-AASESNN----YVNHMAKPQSE FUGRU1_4_PE32 NOISO ITVLLWNRCSSDTSLRFLPHAALVAPSARVGDS-----------------------SISS GASACGROUPII_20_PE8 NOISO ITVLLWNRCSSDSSLRFLPRDT-SAPSPKVGDA-----------------------SISS GORGO15_52_PE3 NOISO VTVLLWNKCSSDKAIQ-FPRRLS--SGFRVDGFEKRAA-ASESNN----YMNHVAKQQSE HORSE1_129_PE4 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKRAAA-SESNN----YVNHVGK-RAE HS15_PE1022 NOISO VTVLLWNKCSSDKAIQ-FPRRSS--SGFRVDGFEKRAA-ASESNN----YMNHVAKQQSE LAMPAGS_1629_PE1 NOISO VTVLLWNKCSSDKAVQ-SPRHLS--SGFRVDVLEKGAA-ASESDS----VAGRV-ARQSV LOXAF28_1_PE9 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFR-DGLEKRAAA-SESNN----YVNHMAK-QSE MACMU7_50_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRRLS--SGFRVDGLEKRAA-ASESNN----YMNHVAKQQSE MICMUGS_2127_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKKTAASESNN-----YVNHMAKQQSE MONDO1_161_PE3 NOISO VTVLLWNKCSSDKAIQ-FPRNWN--NGLRADGLEKRTA-ASESDN----SVNNAARQQPE MOUSE9_PE1247 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKR-SAASESNH----YANHIAKQQSE MYOLUGS_2764_PE1 NOISO VTVLLWNKCSSDKAIQ-FXXXXX--XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXX NEMVE_415_PE90 NOISO ------------------------------------------------------------ OCHPR5803_PE1 NOISO VTVLLWNKCSSDKTIQ-FPRHLS--SGLRVDGLEKRA-VASESNS----YVKHLARQQSE ORNANCONTIG102_1_PE6 NOISO LTVLLWNKCSSDRPAH-LLRQPG--PGPRADGPDQRAAAAQSAGY----AHGPAGGQRDE ORYLA3_11_PE11 NOISO ITVLLWNRCSSNTSIYFLPRAAFVAPSPKIGDE-----------------------GISS PANTR15_71_PE4 NOISO VTVLLWNKCSSDKAIQ-FPRRSS--SGFRVDGFEKRAA-ASESNN----YMNHVAKQQSE PIG1_179_PE2 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDALEKRAAA-SESNN----HVNHMAK-QSE POEGU10RD_PE15 NOISO ------------------------------------------------------------ PONPY15_69_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRRLS--SGFRVDGFEKRAAAASESNN----YMNHVAKQQSE PRIPA_2470_PE4 NOISO ------------------------------------------------------------ PTEVA2316_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKRA-AASESNN----YVNHLAK-QSE RABITUN0095_1_PE3 NOISO VTVLLWNKCSSDRAIQ-FPRHLS--SGFRVDGLEKRA-AASESDN----YVKHMARQQSE RAT8_PE934 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKR-SAASESNH----YANHIAKQQSE SORAR240806_PE1 NOISO VTVLLWNKCSSDKAIQ-FSRHLS--GGFRVDGFEKRA-AASESNS----YVNHPGKPQSD SPETRGS_2734_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRHLS--SGFRVDGLEKRAAASESNH-----YVNHMAKQQSE TARSY6414_PE1 NOISO VTVLLWNKCSSDKATQ-FPRHLS--SGFRADGLEKRAA-ASESNH----YVKHVPRLQSE TETNG5_PE548 NOISO ITVLLWNRCSSNTSLRFLPRAALVAPSPRVGDS-----------------------SISS TRIAD_1257_PE623 NOISO VYIIKWLSDTPIFKENHQQQQA---------------QHSK------------------- TUPGBGS_2674_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRHSS--SGFRVDGLDKRA-AASESNS----YANHVARQQAE TURTR91481_PE1 NOISO VTVLLWNKCSSDKAIQ-FPRHSS--SGFRVDALEKRAAASESNN-----YVNHMAKH-SE XENTR40_1_PE17 NOISO VTVLLWNKCSSNDHTPNLPWDP--QAGLRVDSLDKRAAASESN--------AANGPLRSE MATCH CONSENSUS VTVLLWNKCSSDKAIQ?FPR??????GFRVD??EKRA???S???????????H????QSE

ACYPI_15750_PE7 NOISO ---------------------NYESLVQNIKSIDCL----------INGNNVHVDCLI-K AEDAE_380_PE3 NOISO -KWNH--RYD-----------SVDNQLELTEEIDCV----------INQEY-TIGCRR-E AILMEGL192768_1_2_PE4 ENSAMEG00000014172 EAFPQEQQKAPPVVGSFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- ANOCA1094_PE3 NOISO EASPQEQQKAPPVVAVGGGSRGNKAPGLRYEEIDCL----------INEEH-TIKGRR-- ANOGA_1_PE1164 AGAP005699 -KWPQHHGDS---------GKLLPTPFEQTEEIDCI----------INQEY-AIGCRK-E APIME_525_PE10 NOISO -DWKSK--FQ---------HKDRLNLETGYQEIDCH----------INGDY-SIGCRK-E BOVIN10_17_PE5 NOISO EAFPQEQQKAPPVVGGFNNNGGGRVLGLKYEEIDCL----------INDEH-TIKGRR-- CABRI1_3_PE1525 NOISO -----------------------DLKEKEKEKIECEPTGAVETKCTADNGK-PLRCWK-- CAEELIII_PE1087 NOISO -----------------------DVNED-DKKIECEPPGSIESKCIADNGK-SMKCWK-- CALJA10_13_PE1 NOISO EAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- CANFA30_38_PE2 NOISO EAFPQEQQKAPPVVGSFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- CAVPO0_90_PE6 NOISO EAFPQEQQKAPPVVGGFNSNGGSKAIGLKYEEIDCL----------INDEH-TIKGRR-- CHICK10_PE537 NOISO EASPQEQQKAPPVVGGFN-----KAPGLKYEEIDCL----------INDEH-TIKGRR-- CHOHO23339_PE1 NOISO EAFPQEQQKAPPVVAGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 QKWLNELKKSPSLNGPDEPPRSD--ALPSVSSLECL----------INDQQ-TVQCLKAA CULQU_2638_PE9 NOISO -KWSSHARYE-----------SGENPLELTEEIDCV----------INQEY-TIGCRR-E DANRE25_9_PE30 NOISO EENEGQAPEAPPGS-----------REVAYEQIDCL----------INEDV-LIKGRR-- DANRE7_36_PE10 ENSDARG00000068981 HPQQPQPPEPPPVVG-----------GVRYEEIDCL----------INDDA-TIKGRR-- DROME2R_3_PE54 FBGN0033087 -PLDRSARQS---------SS--GGEATALHDIECS----------INQEY-TVHCKR-D ECHTE200238_PE1 NOISO EGFPQEQQKAPPVVGGFNGNGGSKVLGLKYEEIDCL----------INDDH-TIKGRR-- FUGRU1_4_PE32 NOISO QQHPPQPPEPPPVVG-----------GSKFEEIDCL----------INDEA-SIKCRR-- GASACGROUPII_20_PE8 NOISO QQHPPQPPEPPPVVG--------AASGIKYEDIDCL----------VNDES-TIKGRR-- GORGO15_52_PE3 NOISO EAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- HORSE1_129_PE4 NOISO EAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- HS15_PE1022 NOISO EAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- LAMPAGS_1629_PE1 NOISO EAFPQEQQRAPPVVGG------SKGLGLKYEEIDCL----------INDEH-TIKGRR-- LOXAF28_1_PE9 NOISO EAFPQEQQKAPPVVGGFNGNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- MACMU7_50_PE1 NOISO EAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- MICMUGS_2127_PE1 NOISO EAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- MONDO1_161_PE3 NOISO EASPQEQQKAPPVVGGFNSH-GNKILGLKYEEIDCL----------INDEH-TIKGRR-- MOUSE9_PE1247 NOISO EAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- MYOLUGS_2764_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEIDCL----------INDDH-T-KGRR-- NEMVE_415_PE90 NOISO -----------------------------YEILEVN----------VNGGE-KKLQGRLD OCHPR5803_PE1 NOISO EAFPPEQQKAPPIVG-------NKVLGLKYEEIDCL----------INDEH-TIKGRR-- ORNANCONTIG102_1_PE6 NOISO EASPQEQQRAPPVAGGPDG---RRGPGLRYEEIDCL----------INEDQ-TIRGRR-- ORYLA3_11_PE11 NOISO QQHPPQPPEPPPVVG-----------GVKFEEIDCL----------INDET-TIKGRR-- PANTR15_71_PE4 NOISO EAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- PIG1_179_PE2 NOISO ETFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- POEGU10RD_PE15 NOISO ------------------------------------------------------------ PONPY15_69_PE1 NOISO EAFPPEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- PRIPA_2470_PE4 NOISO ------------------------------------------------------------ PTEVA2316_PE1 NOISO EAFPQEQQKAPPVAGGFSSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- RABITUN0095_1_PE3 NOISO EAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- RAT8_PE934 NOISO EAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIRGRR-- SORAR240806_PE1 NOISO EAFPQEQQKAPPVVGGFSSNGGNKVLGLKYEEIDCL----------INDEH-TIKGRR-- SPETRGS_2734_PE1 NOISO EAFPQEQQKAPPVVGGFNNNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- TARSY6414_PE1 NOISO EAFAQEQQKAPPVVGGFGSNGGSKALGLKYEEIDCL----------INDEH-TIKGRR-- TETNG5_PE548 NOISO QQQPPQPPEPPPVVG-----------GSKFEEIDCL----------INDEV-NIKCRR-- TRIAD_1257_PE623 NOISO -SSIQVQ-QRQD-------QNGANSIQKEYNANQCVNHHQSIKIN-YFNRQ-TFQGKN-- TUPGBGS_2674_PE1 NOISO EGGPQEQQKAPPVVGGFNGNGGSKVLGLKYEEIDCL----------INDEH-TVKGRR-- TURTR91481_PE1 NOISO EAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCL----------INDEH-TIKGRR-- XENTR40_1_PE17 NOISO EASPQEQQKAPPLVG-------SKGTGQKYEEIDCM----------INEEQ-TVRCRK-- MATCH CONSENSUS EAFPQEQQKAPPVVGGF????G?K?LGLKYEEIDCL??????????INDEH?TIKGRR??

ACYPI_15750_PE7 NOISO --NNTVYIPFSFLKNYFEVYGKIIETDENKKKFHWSHSYSK------------------- AEDAE_380_PE3 NOISO --GDEIYLPFSFLSKYFEVYGSLNTV-DGAKRFDWSHSYGK------------------- AILMEGL192768_1_2_PE4 ENSAMEG00000014172 -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- ANOCA1094_PE3 NOISO -EGAEVFLPFSWVEKYFDVYGKVAQY-DGYDRFEFSHSYSK------------------- ANOGA_1_PE1164 AGAP005699 --GDEVYLPFSFLQKYFDVYGSLNVV-DGSRRFDWTHSYGK------------------- APIME_525_PE10 NOISO --GDEVYIPFSFIHKYFEIYGKLATY-DGLERFEWLHSYSK------------------- BOVIN10_17_PE5 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- CABRI1_3_PE1525 NOISO -DEEEVYFPFSYIKKRFDMTGKLGKD---GSTFELFTSYAK------------------- CAEELIII_PE1087 NOISO -DEEDVYFPVSYLKKRFDMTGKLGKD---GSTFELYTSYAK------------------- CALJA10_13_PE1 NOISO -EGTEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- CANFA30_38_PE2 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- CAVPO0_90_PE6 NOISO -EGSEVFLPFTWVEKYFDVYGKVVQY-DGYERFEFSHSYSK------------------- CHICK10_PE537 NOISO -EGSEVFLPFSWVEKYFEVYGKIAQY-DGYDRFEFSHSYSK------------------- CHOHO23339_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 GTDGQVYMPFDFIQNYFEVYGKMKHY-DGYDRFEFQQSYAK------------------- CULQU_2638_PE9 NOISO --GDEVYLPFSFLSKYFEVYGSLNTV-DGAKRFDWAHSYGK------------------- DANRE25_9_PE30 NOISO -EGGEVYLPFSWVEKYFDVYGRLVQY-DGMERFEFSHSYSR------------------- DANRE7_36_PE10 ENSDARG00000068981 -EGSEVYMPFSWMEKYFEVYGKVVQY-DGYDRFEFSHSYSK------------------- DROME2R_3_PE54 FBGN0033087 ENANEVYVPFSFLRNYFDVSGAVSTNSNEVAKFNWVHSTAK------------------- ECHTE200238_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- FUGRU1_4_PE32 NOISO -AGGEIYMPFGWMEKYFEVYGKVAQY-DGYDRFEFQHSYSK------------------- GASACGROUPII_20_PE8 NOISO -EGAEVYLPFSWVEKYFDVYGKVVQY-DGYDRFEFQHSYSK------------------- GORGO15_52_PE3 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- HORSE1_129_PE4 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- HS15_PE1022 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- LAMPAGS_1629_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- LOXAF28_1_PE9 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- MACMU7_50_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- MICMUGS_2127_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- MONDO1_161_PE3 NOISO -EGNEIFLPFTWVEKYFEVYGKMVQY-DGYDRFEFSHSYSK------------------- MOUSE9_PE1247 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- MYOLUGS_2764_PE1 NOISO -EGNEIFLPFSWIEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- NEMVE_415_PE90 NOISO SSSGEPYVPFSFVKEYFEIYGEVQKQ-KEKKVLEWRHSYSE------------------- OCHPR5803_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- ORNANCONTIG102_1_PE6 NOISO -EGPEVYLPFSWVEKYFDVYGRIAQY-DGYERFEFSHSYSK------------------- ORYLA3_11_PE11 NOISO -EGGEIYMPFNWMEKYFEVYGKVVQY-DGYDRFEFQHSYSK------------------- PANTR15_71_PE4 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- PIG1_179_PE2 NOISO -EGNEVFLPFSWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- POEGU10RD_PE15 NOISO ------------------------------------------------------------ PONPY15_69_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- PRIPA_2470_PE4 NOISO ------------------------------------------------------------ PTEVA2316_PE1 NOISO -EGNDIFLPFTWVE-YFDVYGKMVQY-DGYDRF-FSHGYSE------------------- RABITUN0095_1_PE3 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- RAT8_PE934 NOISO -EGNEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- SORAR240806_PE1 NOISO -EGNEVFLPFSWVEKYFDVYGKVVQY-DGYDRFEFSHSYSR------------------- SPETRGS_2734_PE1 NOISO -XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TARSY6414_PE1 NOISO -EGSEVFLPFTWVEKYFDVYGKVVQY-DGYDRFEFSHSYSK------------------- TETNG5_PE548 NOISO -AGGEIYMPFGWMEKYFEVYGKVAQY-DGYDRFEFQHSYSK------------------- TRIAD_1257_PE623 NOISO -FNGKVFIPAEFLSSQFGWVGESQNL-NGEKVWSISKRKAR------------------- TUPGBGS_2674_PE1 NOISO -EGSEVFLPFTWVEKYFDVYGKVVQY-DGYERFEFSHSYSK------------------- TURTR91481_PE1 NOISO -EGNEVFLPFTWVEKYFDVYGK-VQY-DGYDRFEFSHSYSK------------------- XENTR40_1_PE17 NOISO -EGTEVYMPFSWVEKYFEVYGKIAQY-DGFERFEFSHSYSK------------------- MATCH CONSENSUS ?EGNEVFLPF?WVEKYFDVYGKVVQY?DGYDRFEFSHSYSK???????????????????

ACYPI_15750_PE7 NOISO ----------------IYHQNGKYDSRGVFTNFQNYKVEERDRVKCVSASE---GVPVST AEDAE_380_PE3 NOISO ----------------VNNPKGIYDPKGIFMYFENYNVEMRDRVKCISAIE---GVPIST AILMEGL192768_1_2_PE4 ENSAMEG00000014172 ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST ANOCA1094_PE3 NOISO ----------------VYAQRGPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST ANOGA_1_PE1164 AGAP005699 ----------------VNYPKGAYDPRGIFMYFENYNVEMRDRVKCISAID---GVPIST APIME_525_PE10 NOISO ----------------IVNPKGKYDPRGVFMTFENYNVEVRERVKCISGND---GVPIST BOVIN10_17_PE5 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST CABRI1_3_PE1525 NOISO ----------------MRTPDKNYYPLGPFGHFSTYSVETRDRVRCISAKTGISDVPMST CAEELIII_PE1087 NOISO ----------------MRSPDSTYDPLGPFGHFSTYSVETRDRVRCVSAKT---DVPMST CALJA10_13_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST CANFA30_38_PE2 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST CAVPO0_90_PE6 NOISO ----------------VYTQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST CHICK10_PE537 NOISO ----------------VYTQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST CHOHO23339_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 ---------------VIYNPKVPYSYTGVFMTFDSYNVEARDRVKCISGIT---GVPLST CULQU_2638_PE9 NOISO ----------------VNAPKGGYDPKGIFMYFENYNVEMRDRVKCISAIE---GVPIST DANRE25_9_PE30 NOISO ----------------VYAQREPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPIST DANRE7_36_PE10 ENSDARG00000068981 ----------------VYAQREQYHPNGVFMSFEGYNVEVRDRVKCISGVE---GVPLST DROME2R_3_PE54 FBGN0033087 ----------------VNLPRGKYDARGVYMYFENYNVEVRDRVKCISAAE---GVPVST ECHTE200238_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST FUGRU1_4_PE32 NOISO ----------------VYTQREPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST GASACGROUPII_20_PE8 NOISO ----------------VYAQREPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST GORGO15_52_PE3 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST HORSE1_129_PE4 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST HS15_PE1022 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST LAMPAGS_1629_PE1 NOISO ----------------VYTQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST LOXAF28_1_PE9 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST MACMU7_50_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST MICMUGS_2127_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---XXXXXX MONDO1_161_PE3 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST MOUSE9_PE1247 NOISO ----------------VYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST MYOLUGS_2764_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---XXXXXX NEMVE_415_PE90 NOISO ----------------IHESKFEYDPKGTFLWFQGYHVEGRLRVKCICGKE---EVPVSS OCHPR5803_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST ORNANCONTIG102_1_PE6 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGME---GVPLST ORYLA3_11_PE11 NOISO ----------------VYAQREPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST PANTR15_71_PE4 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST PIG1_179_PE2 NOISO ----------------VYTQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST POEGU10RD_PE15 NOISO ------------------------------------------------------------ PONPY15_69_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST PRIPA_2470_PE4 NOISO ----------------MRLPEKTYNSSGLFGHFATYSVETRERVKCINPIT---GVPMST PTEVA2316_PE1 NOISO ----------------VYAQRAPYYPDGVFMSFECYFVEVPDRVQCISGVE---GVPLST RABITUN0095_1_PE3 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST RAT8_PE934 NOISO ----------------VYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST SORAR240806_PE1 NOISO ----------------VYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST SPETRGS_2734_PE1 NOISO XXXXXXXXXXXXXXXXXVPLSTQWGPQGYFYPIQIAQYGL-------------------- TARSY6414_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST TETNG5_PE548 NOISO ----------------VYTQREPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST TRIAD_1257_PE623 NOISO ----------------VVDPIGRYNYKGPFTWFNFYKVEKRERVKYIDSVT---GVPIST TUPGBGS_2674_PE1 NOISO ----------------VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST TURTR91481_PE1 NOISO ----------------VYAQRAPYQPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST XENTR40_1_PE17 NOISO ----------------VYAQRGPYHPDGVFMSFEGYNVEVRDRVKCISGVE---GVPLST MATCH CONSENSUS ????????????????VYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVE???GVPLST

ACYPI_15750_PE7 NOISO QWNPHGYYYPTQIAQFGLSHYSKNLTLP-------SPKVRVLENGQLN------PLWNVP AEDAE_380_PE3 NOISO QWESQGYFYATQIAQFGLSHYSKNLTEP-------EPRRKVIEDGEKE-----LADWRVP AILMEGL192768_1_2_PE4 ENSAMEG00000014172 QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKNSKPNDWTVP ANOCA1094_PE3 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPNVVVYETAEEREPGGRSGDWTVP ANOGA_1_PE1164 AGAP005699 QWESQGYFYATQIAQFGLSHYSKNLTEP-------EPRRKTVEDGERE-----TATWIVP APIME_525_PE10 NOISO QWESQGYYYPTQIAQFGLSHYSKNLTEP-------EPHRKIIEDSDKV-----KREWIIP BOVIN10_17_PE5 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKNSKPNDWTVP CABRI1_3_PE1525 NOISO QWDPIPYYYPIQIAQYGLQHYSRIKLDSVSNKSDD--NAEVL-------VGVQSKEWKGA CAEELIII_PE1087 NOISO QWDPIPYYYPIQISQYGLQHYSRMKLDSISNKSEASPKDDVI-------LGVNSKEWKGA CALJA10_13_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKNSKPNDWTVP CANFA30_38_PE2 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKN-KPNDWTVP CAVPO0_90_PE6 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------SPHIEVYETAEDRDKNSKTNDWTVP CHICK10_PE537 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEEKDRGSRAAEWTVP CHOHO23339_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEIYETAEDKYRNSKPNDWTVP CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 QWHIQGYYYGIQIAQFGMSHYSKELVQR-------PPTKQVYENAEDSI----QGQWKPS CULQU_2638_PE9 NOISO QWESQGYFYATQIAQFGLSHYSKNLTEP-------EPRRKIVEDGDKE-----MAEWRVP DANRE25_9_PE30 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPDIKIYGMLEEKEGG--SSQWDVP DANRE7_36_PE10 ENSDARG00000068981 QWGPQGYFYAIQIAQYGLSHYSKNLTER-------PPHVEVYDTAEERDSRS--SAWTVP DROME2R_3_PE54 FBGN0033087 QWEKRGYFYPTQIAQFALSHYSKNLTEP-------APRVRVLEDGDGN-----QMEWSTP ECHTE200238_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDKDRNSKPNDWVVP FUGRU1_4_PE32 NOISO QWGPQGYFYAIQIAQYGLSHYSKNLTER-------PPHVEIYDTAEERDSRAITHPWSVP GASACGROUPII_20_PE8 NOISO QWGPQGYFYAIQIAQYGLSHYSKNLTER-------APHVEVYDTAED--------RWTAS GORGO15_52_PE3 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDK-NKPNDWTVP HORSE1_129_PE4 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKNSKLNDWTVP HS15_PE1022 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDK-NKPNDWTVP LAMPAGS_1629_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPRVEVYETAEGRDRDSQPSAWAVP LOXAF28_1_PE9 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDKDKNSKPNDWAVP MACMU7_50_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKNNKPNDWTVP MICMUGS_2127_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX-XXXXX---XXXXXXXXXXX MONDO1_161_PE3 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDKDKHSRPNDWTVP MOUSE9_PE1247 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDRNIRPNEWTVP MYOLUGS_2764_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX-XXXXX---XXXXXXXXXXX NEMVE_415_PE90 NOISO QWNPNGHYYPIQIAQYGLSHYSSYIAERDD-----TGKVKLFEDAESV----FDSNWVVS OCHPR5803_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKGSKASDWTVP ORNANCONTIG102_1_PE6 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHVEVYETAEDKDRNGRSNEWIVP ORYLA3_11_PE11 NOISO QWGPQGYFYAIQIAQYGLSHYSKNLTER-------APHVEVYDTAEEKDSRA-TAPWSVP PANTR15_71_PE4 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDK-NKPNDWTVP PIG1_179_PE2 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKSNKLSDWTVP POEGU10RD_PE15 NOISO ------------------------------------------------------------ PONPY15_69_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKNNKPNDWTVP PRIPA_2470_PE4 NOISO QWNVIPYYYPIQIAQYGLEHYSRLLSQG-------NESRSVV-------VGVDSKEWRGA PTEVA2316_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDKTSKPNDWTVP RABITUN0095_1_PE3 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDRSSKSGDWTVP RAT8_PE934 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDRNIRPNEWTVP SORAR240806_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDRNSKPNDWTVP SPETRGS_2734_PE1 NOISO -----------------------SHYSKNLTE---PPHIE-YETAD---DDIKPIDWTVP TARSY6414_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHIEVYETAEDRDRDTRPGDWTVP TETNG5_PE548 NOISO QWGPQGYFYAIQIAQYGLSHYSKNLTER-------PPHVESYDTAEERDGRAAAAPWSVP TRIAD_1257_PE623 NOISO QWSQKGYFYPTQICQFALSHFTRLLLNGTKIN---Q--RILFD----CKSMDIVSTWKVH TUPGBGS_2674_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHVEVYETAEDRDKGSKPGDWSVP TURTR91481_PE1 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTXXXXXX---XXXXX-XXXXX---XXXXXXXXXXX XENTR40_1_PE17 NOISO QWGPQGYFYPIQIAQYGLSHYSKNLTEK-------PPHVEVYEKADEK--SGVTGVWKIP MATCH CONSENSUS QWGPQGYFYPIQIAQYGLSHYSKNLTEK???????PPHIEVYETAED?D???????WTVP

ACYPI_15750_PE7 NOISO -KTS---KIQIAFNAQ--VNSNVIDFISTE--DF---------------FISFDVALSLS AEDAE_380_PE3 NOISO -KNS---SLSRSYMKD--KDTTVVHFSTGK--HFDSAIALPMD-HVLDLVLSVNLLLR-P AILMEGL192768_1_2_PE4 ENSAMEG00000014172 -KGC---FMASVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T ANOCA1094_PE3 NOISO -KGG---SVTTVP--DKARFTNVKHFVVP---ENSEGAWLALG-NGRDFILSLDLRLV-G ANOGA_1_PE1164 AGAP005699 -KGS---SMNRTIDRARAGAGAVLSFSTGK--SFDTAVVLPMD-HVLDLVLSVDVLLK-P APIME_525_PE10 NOISO -QGS---IASRIFDKY--VNSYVMKFATPE--TSTSGITLKLD-HVLDFVLKWDFNIK-D BOVIN10_17_PE5 NOISO -KGC---FMASVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T CABRI1_3_PE1525 NOISO -AG-MHETTERLFFND-EEKGKVVNISAGHA-LSNAGAYVYLDKSPDLHVISFDWKPYDA CAEELIII_PE1087 NOISO -AG-MHETTERLFFND-EQMGKVVNISAGAA-LANAGAYVYLDKSPDLHVISFDWKPYEA CALJA10_13_PE1 NOISO -KGC---FMANVA--DKSRLTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T CANFA30_38_PE2 NOISO -KGC---FMASVA--EKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T CAVPO0_90_PE6 NOISO -KGC---FMASVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T CHICK10_PE537 NOISO -KGC---SLSTVP--DKAKFTEQLFVCFA---ENTEGVSLQLG-NARDFIISFDLKLV-T CHOHO23339_PE1 NOISO -KGC---FIASVA--DKSRFTNVKQFIAP---ETSEGVSLHLG-NTKDFIISFDLKFL-T CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 NKDC---IVDIAK--DTETQSNVIKFSTPVSIPLGSGAALILG-NTIEHILSFDLKMI-T CULQU_2638_PE9 NOISO -KNS---SLSRAFVRE--KESTVVHFSTGK--QFDSAITLPMD-HVLDLVLSVNLLLR-P DANRE25_9_PE30 NOISO -KGC---TLSKIQ--DQGRSGFVHHFVTA---ENSEGVSLVLD-NAKDFVLTFDVKFI-S DANRE7_36_PE10 ENSDARG00000068981 -KGC---SLTRVY--DKTRATSVRQFSAP---ENSEGVSLPLG-NTKDFIISFDLKFT-S DROME2R_3_PE54 FBGN0033087 -KTS---NMTRIWHHK--FNTSVVQFETAP--GYEGVISIALN-QTLDLLLSVDLLLV-T ECHTE200238_PE1 NOISO -KGC---FMSNVA--DKSRFTNVKQFTAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T FUGRU1_4_PE32 NOISO -KGC---SLSRVH--DKSRATSVRQFNAQ---ESSEGVSLQLG-NSKDFILSLDIKFT-S GASACGROUPII_20_PE8 NOISO -KGC---VLSRVH--DKSRATSVRQFNALV--ESSEGVSLQLG-NSKDFILSLDVKFV-S GORGO15_52_PE3 NOISO -KGC---FMANVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T HORSE1_129_PE4 NOISO -KGC---FVASVA--DKSRFTNVKQFLAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T HS15_PE1022 NOISO -KGC---FMANVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T LAMPAGS_1629_PE1 NOISO -KGC---FVASVA--EESRFTNVKQFIAP---ETSDGVSLQLG-NTKDFIISFDLKFL-T LOXAF28_1_PE9 NOISO -KGC---FMASVA--DRSRFTNVKQFIAP---ETSDGVSLQLG-NTKDFIISFDLKFL-T MACMU7_50_PE1 NOISO -KGC---FMANVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NMKDFIISFDLKFL-T MICMUGS_2127_PE1 NOISO -XXX---XXXXXX--XXXX--XXXXXXXXX--XTSEGVSLQLG-NTKDFIISFDLKFL-T MONDO1_161_PE3 NOISO -KGC---FMTSVA--DKSRFTNVKQFVAP---ETSEGVSLLLG-NTKDFIISFDLKFL-T MOUSE9_PE1247 NOISO -KGC---FMASVA--DKSRSTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKLL-T MYOLUGS_2764_PE1 NOISO -XXX---XXXXXX--XXXX--XXXXXXXXX--XTSEGVSLQLG-NTKDFIISFDLKFL-T NEMVE_415_PE90 NOISO -EPN---KVENIV--DEERGSRVIKFWTQG--FVGEGVSLHLDSSTKEYVLSFHLKQT-G OCHPR5803_PE1 NOISO -KGC---FMASVA--DKARFTNVKQFIAP---ETSEGVSLPLG-NTRDFIISFDLKFL-T ORNANCONTIG102_1_PE6 NOISO -KGC---SLVSVA--DRSRFTNVKQFVAP---ESTEGVSLPLG-NTKDFIISFDLKFQ-T ORYLA3_11_PE11 NOISO -KGC---SLNRVH--DKFRSTSVRQFSAP---ESSEGVSLQLG-NSRDFILSLDIKFV-S PANTR15_71_PE4 NOISO -KGC---FMANVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T PIG1_179_PE2 NOISO -KGC---FMASVT--DKSRFTNVKQFIAP---ETSDGVSLQLG-NTKDFIISFDLKFL-T POEGU10RD_PE15 NOISO ------------------------FAFFA---ESSEGVSLELN-NGRDFIISFDLKLL-S PONPY15_69_PE1 NOISO -KGC---FMANVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T PRIPA_2470_PE4 NOISO -PGSMDETSERVFFVD-EEGKSTVNFSTKDD-ISNPGVYVSLSSDSDLATVSFSFKSHSP PTEVA2316_PE1 NOISO -KGC---SMASVA--DKSRFTNVKQFVAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T RABITUN0095_1_PE3 NOISO -KGC---FMASVA--EKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T RAT8_PE934 NOISO -KGC---FMASVA--DKSRSTNVKQFIAP---EAGEGVSLQLG-NTKDFIISFDLKFL-T SORAR240806_PE1 NOISO -KGC---FVASVA--DKSRFTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFV-T SPETRGS_2734_PE1 NOISO -GXX---XXXXXX--XXXX--XXXXXXXXX--XTSEGVSLQLG-NTKDFIISFDLKFL-T TARSY6414_PE1 NOISO -KGC---FMASVA--DKSRFTNVKQFSAP---ETSEGVSLELG-NTKDFIISFDLKFL-T TETNG5_PE548 NOISO -KGC---SLSRVH--DKSRATSVRQFSAQ---ESSEGVSLQLG-NSKDFILSLDIKFT-- TRIAD_1257_PE623 NOISO QT-T---SIQCIDAIVDGPNKRVMKFAQS---HSSKAMSLNMQSSFKRFIARFEVQFK-G TUPGBGS_2674_PE1 NOISO -KGC---FMASVA--DKSRLTNVKQFIAP---ETSEGVSLQLG-NTKDFIISFDLKFL-T TURTR91481_PE1 NOISO -XXX---XXXXXX--XXXX--XXXXXXXXX--XTSDGVSLQLG-NTKDFIISFDLKFL-T XENTR40_1_PE17 NOISO -KGA---SVTTVF--DSTKNSHVKHFVVP---ENLEGASLTLG-NIKDFILSLDVKFT-T MATCH CONSENSUS ?KGC???????V???DKSR?TNVKQF?AP???ETSEGVSLQLG?NTKDFIISFDLKFL?T

ACYPI_15750_PE7 NOISO TSSSIVISIKEIKDQEVWNLHYICSRTF---------IFAKG-------------HNIYH AEDAE_380_PE3 NOISO N-SSFMVTLQNRETQKLYNVIYILADLM---------MSVQD-------------DNIYY AILMEGL192768_1_2_PE4 ENSAMEG00000014172 N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY ANOCA1094_PE3 NOISO N-GSVSVVLETTEKGPPFTLHYVSDSHL---------ISFKD-------------RDVSY ANOGA_1_PE1164 AGAP005699 N-STLCVTLQNRETQKLYHVYYILADLL---------IGVQD-------------ENIYY APIME_525_PE10 NOISO N-GSIMITLQSRERKEIYYLHYITSNIV---------LHTYN-------------NHVYY BOVIN10_17_PE5 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY CABRI1_3_PE1525 NOISO N-SSFTVLAKMKQDDLLVLINYVFSEGDGKCVWQDEEKSFDDETIVLKPRKDGQVSYSYS CAEELIII_PE1087 NOISO N-SSFTVLAKMKQDDLLVLINYVYSEGNGKCVWQEEERI-SDDYIVQKPKKDGQVSYSYS CALJA10_13_PE1 NOISO N-GSVSVVLETTEKNQLFTIHYVSNAQL---------IAFKE-------------RDIYY CANFA30_38_PE2 NOISO N-GSVSVVLETTEKNQLFTIHYVSNTQL---------IAFKE-------------RDIYY CAVPO0_90_PE6 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDVYY CHICK10_PE537 NOISO N-GSISVVLETTEKNQLFTVHYVSNTQL---------IAFRE-------------RDIYY CHOHO23339_PE1 NOISO N-GSVSIVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 N-GSLSVVLETNDKLKQYTIHYITSNIV---------IDFDH-------K-----SNIYY CULQU_2638_PE9 NOISO N-SSFTVTLQNRETQKLYNVIYILADLM---------MSVQD-------------DNIYY DANRE25_9_PE30 NOISO N-GSVSVVLETTEKGPYFIIHYITSPLL---------LSFKD-------------REVIY DANRE7_36_PE10 ENSDARG00000068981 N-GSVSVILETTEKGPPFVIHYVTTTQL---------ILLKD-------------RDITY DROME2R_3_PE54 FBGN0033087 NSSSLMITVQNRDTRHNYSLHYIPADLL---------LSVQD-------------TNIYY ECHTE200238_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDVYY FUGRU1_4_PE32 NOISO N-GSVSVVLETTEKGPPFTIHYVTSTQL---------IAFKD-------------REITY GASACGROUPII_20_PE8 NOISO N-GSVSVTLETTEKGPPFTIHYVTNAQL---------IAFKD-------------HEITY GORGO15_52_PE3 NOISO N-GSVSVVLETTEKNQLFTIHYVSNAQL---------IAFKE-------------RDIYY HORSE1_129_PE4 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY HS15_PE1022 NOISO N-GSVSVVLETTEKNQLFTIHYVSNAQL---------IAFKE-------------RDIYY LAMPAGS_1629_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKG-------------RDIYY LOXAF28_1_PE9 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY MACMU7_50_PE1 NOISO N-GSVSVVLETTEKNQLFTIHYVSNAQL---------IAFKE-------------RDIYY MICMUGS_2127_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYISNAQL---------IAFKE-------------RDIYY MONDO1_161_PE3 NOISO N-GSVSVVLETTEKNQLFTVHYISNTQL---------IAFKE-------------RDIYY MOUSE9_PE1247 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFRD-------------RDIYY MYOLUGS_2764_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY NEMVE_415_PE90 NOISO D-VIITVSIETK-HNTQHLIHYTSDEEM---------ISVKQ-------------NEIFM OCHPR5803_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IALKD-------------RDVYY ORNANCONTIG102_1_PE6 NOISO N-GSVSVVLETTEKNQLFTIHYVSNTQL---------IAFRD-------------RDVYY ORYLA3_11_PE11 NOISO N-GSVSVVLETTEKGPPFTIHYVTSTQL---------IAFKD-------------RDITY PANTR15_71_PE4 NOISO N-GSVSVVLETTEKNQLFTIHYVSNAQL---------IAFKE-------------RDIYY PIG1_179_PE2 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY POEGU10RD_PE15 NOISO N-GSVSVVLETTERNQLFTVHYVSSTQL---------IALRD-------------RDIFY PONPY15_69_PE1 NOISO N-GSVSVVLETTEKNQLFTIHYVSNAQL---------IAFKE-------------RDIYY PRIPA_2470_PE4 NOISO N-SSFSILLTVKEGNQLILLHYVPR-DDDRCVWSEDSKKMVDNQI------------TFF PTEVA2316_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY RABITUN0095_1_PE3 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKD-------------RDIYY RAT8_PE934 NOISO N-GSVSVVLETTDKNQLFTVHYVSNTQL---------IAFKD-------------RDIYY SORAR240806_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IALKD-------------RDIYY SPETRGS_2734_PE1 NOISO N-GSISVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY TARSY6414_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKD-------------RDIYY TETNG5_PE548 NOISO N-GSVSVVLETTEKGPPFVIHYVTSTQL---------IAFKD-------------RDVTY TRIAD_1257_PE623 NOISO S-GSISFLVTT-KRQQQFTIRYSTAKVG---------VSFSE-------R-S---KTVIY TUPGBGS_2674_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY TURTR91481_PE1 NOISO N-GSVSVVLETTEKNQLFTVHYVSNTQL---------IAFKE-------------RDIYY XENTR40_1_PE17 NOISO N-GSISVVMETTEKNQIFTVHYITNTQL---------IAFRD-------------HDVFY MATCH . . : * CONSENSUS N?GSVSVVLETTEKNQLFTVHYVSNTQL?????????IAFK??????????????RDIYY

ACYPI_15750_PE7 NOISO GMHCGREFGWKKLTRNVLVDLQKGLHVL--KKTTAKMFRSKY----KLCDFKLYGVGFLD AEDAE_380_PE3 NOISO GIGQNSTSTWRRLTRDLFVDLQKGLPQYINTEKRRKMRRTEL----KVVEISFLGNGSFD AILMEGL192768_1_2_PE4 ENSAMEG00000014172 GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD ANOCA1094_PE3 NOISO GIGP--RSGWSTLTRDLVTDLRKGVGLSHTKAVK-PTKIMPR----KVVRLVVRGRGFLD ANOGA_1_PE1164 AGAP005699 GIGLNCTGGWKHLTRDLFVDLQKGLPQYASTDKRRKMRRTEL----KVVEISLLGNGSID APIME_525_PE10 NOISO GIGQI-NHQWRRFTRDLVIDLQKGLYL--NDKNKKKMSRSKL----KIVKITLYGSGMID BOVIN10_17_PE5 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTRIMPK----KVVRLIAKGKGFLD CABRI1_3_PE1525 NOISO YSGSAPIGEWSTVTRDILVDVARALSSGE---NRKKDDNVVL----HPGDLRLVSLGFRG CAEELIII_PE1087 NOISO YIGNSPIGEWSTVTRDLLVDVARALSSGD---NRKKDDNVVL----HAGDLRLVSLGFRG CALJA10_13_PE1 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD CANFA30_38_PE2 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD CAVPO0_90_PE6 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD CHICK10_PE537 NOISO GIGA--RTSWSTITRDLVTDLRKGVGLSNTKAVK-QTRIMPK----KVVRLIAKGRGFLD CHOHO23339_PE1 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD CIOSAREFTIG_16_1_PE76 ENSCSAVG00000006006 GLGA--SRHWRHIARDLLTDLKKGIGLTDTRQAK-KVRINIL----KVARLTVRGSGFID CULQU_2638_PE9 NOISO GIGQNSTSNWRRLTRDLFVDLQKGLPQYINTEKRRKMRRTEL----KVVEISFLGNGSFD DANRE25_9_PE30 NOISO GIGP--RATWSTVSRDLVTDLRKGVGLSNTKVVK-ATKIMPR----RVVQLVLKGSGFIS DANRE7_36_PE10 ENSDARG00000068981 GIGP--RTTWTTVTRDLLTDLRKGIGLSNTKAVK-ATKTMPR----RVVKLVVHGTGTID DROME2R_3_PE54 FBGN0033087 GLGGSALNKWRHITRDLHIDLQKGIMGD--KRSPLKIRRSDL----EVISIGFLGLGFFD ECHTE200238_PE1 NOISO GIGP--RTSWGTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLVAKGKGFLD FUGRU1_4_PE32 NOISO GIGS--RTTWSTLTRDLLTDLRKGVGLSNTKAVK-ATKIMPR----RVVRLVLNGRGFVD GASACGROUPII_20_PE8 NOISO GIGA--RGAWSTLTRDLLTDLRKGVGLSNTKAVK-ATKIMPR----RVVRLVLHGRGFVD GORGO15_52_PE3 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD HORSE1_129_PE4 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD HS15_PE1022 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD LAMPAGS_1629_PE1 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD LOXAF28_1_PE9 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPR----KVVRLIAKGKGFLD MACMU7_50_PE1 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVVRLIAKGKGFLD MICMUGS_2127_PE1 NOISO GIGP--RTSWSTVTRDLVTDLRKGVGLSNTKAVK-PTKIMPK----KVV