Alignment of the gene Family HOG000230932 of HOGENOM

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Isoforms are ON
AILMEGL192924_1_1_PE17 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY ANOCA1303_PE6 NOISO ----MEPRKLITATDNQYSGMLLKALDEQRGHGLFCDVTVIVEDRKFRAHRNVLSASSTY BOVINUN_004_305_PE1 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY CALJAX_111_PE12 ENSCJAG00000004915 ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY CALJAX_111_PE13 ISOFORMIN ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY CALJAX_111_PE14 ISOFORMIN ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY CANFAX_97_PE7 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY CAVPO69_1_PE1 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY CHICK4_PE425 NOISO ----MEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY DANRE14_36_PE22 NOISO ----MSKLKLISVVDTQYPGSLLKNINDERHNGLFCDVTIVVQDRKFRAHKCVLSASSTY DASNOGS_6096_PE1 NOISO ----MESRKLISATDTQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY ECHTEGS_7283_PE1 NOISO ----MESRKLISATDTQYSGNLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY ERIEUGS_7429_PE1 NOISO ----MESRKLISATDIQYSGNLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNVLSASSTY FELCAGS_4068_PE1 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGRGLFCDVTVIVEDRKFRAHRNILSASSTY FUGRU5_1_PE78 ENSTRUG00000010561 ----MPGLKLISVTDTQYPEAVLRSLNEQRSHGLFCDVTIIIQDKKFRAHKTVLSASSTY FUGRU5_1_PE79 ISOFORMIN LSTVMPGLKLISVTDTQYPEAVLRSLNEQRSHGLFCDVTIIIQDKKFRAHKTVLSASSTY GASACGROUPIV_7_PE54 NOISO ----MPSLKLISATDTQYPVAVLNSMNVQRNHGLFCDVTIIIQDRKFRAHKTILSASSTY GORGOX_121_PE11 ENSGGOG00000010306 ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY GORGOX_121_PE12 ISOFORMIN ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY HORSEX_98_PE2 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY HSX_PE2147 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY LAMPAGS_2965_PE1 NOISO ----METRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY LOXAF32_11_PE10 NOISO ----MEGRKLISATDTQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY MACMUX_121_PE17 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY MONDOX_29_PE16 NOISO ----MESRKLISATDIQYSGNLLNSLNEQRDHGLFCDVTVIVEDRKFRAHRNVLSASSTY MOUSEX_PE465 ENSMUSG00000048047 ----MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY MOUSEX_PE466 ISOFORMIN ----MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY MOUSEX_PE467 ISOFORMIN ----MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY ORNANULTRA390_1_PE18 ISOFORMIN SRVGMESKKLISATDTQYSGNLLKSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY ORNANULTRA390_1_PE19 ENSOANG00000002588 ----MESKKLISATDTQYSGNLLKSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY ORYLA10_6_PE16 NOISO ESFDMPSLKLISATDTLYSAAILKSLDEQRSIGLFCDVTIIVQDKKFRAHKTILSASSTY PANTRX_120_PE11 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY PIGX_97_PE8 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY POEGU4A_10_PE20 NOISO ----MEGKKLISATDTQYSSVLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY PONPYX_120_PE11 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTY PROCAGS_6305_PE1 NOISO ----MEGRKLISATDTQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNVLSASSTY PTEVA6684_PE1 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY RABITX_96_PE3 NOISO ----MESRKLISATDIQYSGSLLNTLNEQRGHGLFCDVTVIVEDRKFHAHRNILSASSTY RATX_PE34 NOISO ----MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY SORARGS_6034_PE1 NOISO ----MESRKLISATDIQYSSSLLNALNEQRSHGLFCDVTVIVEDRKFRAHRNVLSASSTY SPETRGS_4895_PE1 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY TETNG1_PE265 NOISO ----MSGLKLISVTDTQYPEAVLKSLNEQRSHGLFCDVTIIIQDKKFRAHKTVLSASSTY TUPGBGS_4719_PE2 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY TURTR110299_PE1 NOISO ----MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTY XENTR10_6_PE3 NOISO ----METKKLITATDTQYSGILLNALNDQRMQGLYCDVTVIVEDRKFRAHRNILSACSTY MATCH * ***:..* *. :*. :: :* **:****::::*:**:**: :***.*** CONSENSUS ????ME??KLISATD?QYS??LL?SLNEQRGHGLFCDVTVIVEDRKFRAH?NILSASSTY

AILMEGL192924_1_1_PE17 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL ANOCA1303_PE6 NOISO FQQLFSVAGQVVELNFVRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFLADL BOVINUN_004_305_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL CALJAX_111_PE12 ENSCJAG00000004915 FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL CALJAX_111_PE13 ISOFORMIN FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL CALJAX_111_PE14 ISOFORMIN FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL CANFAX_97_PE7 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL CAVPO69_1_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRADLLDELIKSGQLLGVKFIAEL CHICK4_PE425 NOISO FHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADL DANRE14_36_PE22 NOISO FRQLFSVAGKVVELNFIKADIFDMVLNYIYTSQMFRVRSDRLEDLINAGQILGVTFIANL DASNOGS_6096_PE1 NOISO FHQLFAVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL ECHTEGS_7283_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL ERIEUGS_7429_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRADLLDELIKSGQLLGVKFIAEL FELCAGS_4068_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL FUGRU5_1_PE78 ENSTRUG00000010561 FYQLFTVAGQVIELNFIRAEIFEEILNYIYTAKICRIRSDLLEELISAGQILGVKFIANL FUGRU5_1_PE79 ISOFORMIN FYQLFTVAGQVIELNFIRAEIFEEILNYIYTAKICRIRSDLLEELISAGQILGVKFIANL GASACGROUPIV_7_PE54 NOISO FHQLFSVAGQVIELNFIKAEIFEEILNYIYSSKIYRVRSDMLEELINAGQILGVKFIANL GORGOX_121_PE11 ENSGGOG00000010306 FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL GORGOX_121_PE12 ISOFORMIN FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL HORSEX_98_PE2 NOISO FHQLFLVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL HSX_PE2147 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL LAMPAGS_2965_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL LOXAF32_11_PE10 NOISO FHQLFAVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL MACMUX_121_PE17 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL MONDOX_29_PE16 NOISO FHQLFSVAGQVVELNFLRAEIFAEILNYIYSSKLMRIRSDLLDEIIKSGQLLGVKFIAEL MOUSEX_PE465 ENSMUSG00000048047 FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKVVRVRADLLDELIKSGQLLGVKFIAEL MOUSEX_PE466 ISOFORMIN FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKVVRVRADLLDELIKSGQLLGVKFIAEL MOUSEX_PE467 ISOFORMIN FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKVVRVRADLLDELIKSGQLLGVKFIAEL ORNANULTRA390_1_PE18 ISOFORMIN FHQLFSVAGQVVELSFIRAEIFAEILNFIYSSKIIRVRSDLLDELIKSGQLLGVKFIADL ORNANULTRA390_1_PE19 ENSOANG00000002588 FHQLFSVAGQVVELSFIRAEIFAEILNFIYSSKIIRVRSDLLDELIKSGQLLGVKFIADL ORYLA10_6_PE16 NOISO FHQLFSVAGQVIELNFIRPEIFEQILNYIYSSRIVRVRSDMLEELIQAGQVLGVKFIANL PANTRX_120_PE11 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL PIGX_97_PE8 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL POEGU4A_10_PE20 NOISO FHQLFSVAGQVVELSFVRAEIFAEILNYIYSSKIISVRSDLLDELIKSGQELGVKFIADL PONPYX_120_PE11 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL PROCAGS_6305_PE1 NOISO FHQLFAVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL PTEVA6684_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL RABITX_96_PE3 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRADLLDELIKSGQLLGVKFIAEL RATX_PE34 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRADLLDELIKSGQLLGVKFIAEL SORARGS_6034_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYMYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL SPETRGS_4895_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRADLLDELIKSGQLLGVKFIAEL TETNG1_PE265 NOISO FYQLFTVAGQVIELNFIRAEIFEEILNYIYSAKICRIRSDLLEELISAGQMLGVEFIAKL TUPGBGS_4719_PE2 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIXXX TURTR110299_PE1 NOISO FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAEL XENTR10_6_PE3 NOISO FHQLFSVAGQVVELNFIKADIFAEILNYIYSSKIVRVRCDMLEELIKSGKLLGVPFIAEL MATCH * **: ***:*:**.*::.:** :**::*:::: :*.* ::::*.:*: *** *: CONSENSUS FHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKI?RVR?DLLDELIKSGQLLGVKFIA?L

AILMEGL192924_1_1_PE17 NOISO GVPLSQVKSISGTSQDGNAETLPPGSSDKNLEIQKS--KDEA-QDNGATIMPIITESFSL ANOCA1303_PE6 NOISO GAPLQQVKNMSGGMGPGASDIPNPDA--NSLEAQNPPAQP-K-TRNLIDERPVIMETFSL BOVINUN_004_305_PE1 NOISO GVPLSQVKSISGTAQDGNAENSPP-------EIQKS--KDES-QENGATIMPIITESFSL CALJAX_111_PE12 ENSCJAG00000004915 GVPLSQVKSISGTAQDGNTEPLPPDSGEKNLVIQKS--KDEA-QDNGATIMPIITESFSL CALJAX_111_PE13 ISOFORMIN GVPLSQVKSISGTAQDGNTEPLPPDSGEKNLVIQKS--KDEA-QDNGATIMPIITESFSL CALJAX_111_PE14 ISOFORMIN GVPLSQVKSISGTAQDGNTEPLPPDSGEKNLVIQKS--KDEA-QDNGATIMPIITESFSL CANFAX_97_PE7 NOISO GVPLSQVKSISGTSQDGNAETLPPGSSDKNLEIQKS--KDEA-QDNGATIMPIITESFSL CAVPO69_1_PE1 NOISO GVPLSQVKGISATSQDGNADTLPPGSSDKNLEIQKS--KDEA-QDNGATIMPIITESFSL CHICK4_PE425 NOISO SVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQE--GREVTGWMPVITESFSL DANRE14_36_PE22 NOISO AIPLAQVKGLPGLSKDGDNNIVSS---------------PE-KPEDGGVNMPIITETFSL DASNOGS_6096_PE1 NOISO GVPLSQVKSISGTAQDGNAETLPPDSSGKSLEIQKS--KDE---DNGATIMPIITESFSL ECHTEGS_7283_PE1 NOISO GVPLSQVKSISS------AEPLPPGSNDKNLEMQKS--KDEA-QDAGTTVMPIITESFSL ERIEUGS_7429_PE1 NOISO GVPLSQVKSISGQVQDESAESLPPDSSDKNLEVQKS--KDDS-QDNGVTAMPIITESFSL FELCAGS_4068_PE1 NOISO GVPLSQVKSISGTAQDGNAETLPPGSGDKNLEMPKS--KDEA-QDNGATIMPIITESFSL FUGRU5_1_PE78 ENSTRUG00000010561 ASPLSQFKGLSGLSKETEN-----------------------KNDALTEMMPIITESFSL FUGRU5_1_PE79 ISOFORMIN ASPLSQFKGLSGLSKETEN-----------------------KNDALTEMMPIITESFSL GASACGROUPIV_7_PE54 NOISO GSPLSHVKGLPGLSKETETES---------------------KSDAPAEAMPIIAESFSI GORGOX_121_PE11 ENSGGOG00000010306 GVPLSQVKSISGTAQDGNTETLPPDSGDKNLVIQKS--KDEA-QDNGATIMPIITESFSL GORGOX_121_PE12 ISOFORMIN GVPLSQVKSISGTAQDGNTETLPPDSGDKNLVIQKS--KDEA-QDNGATIMPIITESFSL HORSEX_98_PE2 NOISO GVPLSQVKSISGTAQDGNTDTLPPGSSDKNLEIQKS--KDEA-QDNGATIMPIITESFSL HSX_PE2147 NOISO GVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKS--KDEA-QDNGATIMPIITESFSL LAMPAGS_2965_PE1 NOISO GVPLSQVKSISGTAQDGNAETLPPGSSDKNLEIQKS--KDEA-QDNGATIMPIITESFSL LOXAF32_11_PE10 NOISO GVPLSQVKSISGATQDGNAETVPPGSDDKNLEIQKS--KDEA-QDNGTTIMPIITESFSL MACMUX_121_PE17 NOISO GVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKS--KDEA-QDNGATIMPIITESFSL MONDOX_29_PE16 NOISO GVPLSQVKSISGSIKPDSGETLS-GTDENGLQMQKA--ENEG-SDAGVTMMPVITETFSL MOUSEX_PE465 ENSMUSG00000048047 GVPLSQVKSISGTEQDGTAETLPSSSSDKSLDMEKS--KDEA-QDNGATVMPIITESFSL MOUSEX_PE466 ISOFORMIN GVPLSQVKSISGTEQDGTAETLPSSSSDKSLDMEKS--KDEA-QDNGATVMPIITESFSL MOUSEX_PE467 ISOFORMIN GVPLSQVKSISGTEQDGTAETLPSSSSDKSLDMEKS--KDEA-QDNGATVMPIITESFSL ORNANULTRA390_1_PE18 ISOFORMIN GVPLSQVKSISGS-------------DEKDLEMQK------------------------- ORNANULTRA390_1_PE19 ENSOANG00000002588 GVPLSQVKSISGEAKDGTSETSSPGSDEKDLEMQKS--KHEG-HEVGAPAMPIITESFSL ORYLA10_6_PE16 NOISO GSPLSQVKGIPGLSKETDA-----------------------KNDGCNEVLPVITESFSI PANTRX_120_PE11 NOISO GVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKS--KDEA-QDNGATIMPIITESFSL PIGX_97_PE8 NOISO GVPLSQVKSISGTPQDGNAETLPPGSSDKNLEIQKS--KDEA-QDNGATIMPIITESFSL POEGU4A_10_PE20 NOISO GIPPAEGKNVPSEVKDSASGTSASSPNQRDAETQVTVIRPE--GQEAADGMPVITQSFSL PONPYX_120_PE11 NOISO GVPLSQVKSISGAAQDGNTEPLPPDSGDKNLVIQKS--KDEA-QDNGATIMPIITESFSL PROCAGS_6305_PE1 NOISO GVPLSQVKSISGATQDGDAENLTPGSNDKNLEIQKS--KDES-QDSGTTIMPIITESFSL PTEVA6684_PE1 NOISO GVPLSQVKSISGTAQDGNAETSPPGSSDKNLEIQKS--KDEA-QDNGAAIMPIITESFSL RABITX_96_PE3 NOISO GVPLSQVKSISGTAQDGSAEAIPPGSNDKNLVIQKS--KEEA-QDNGATIMPIITESFSL RATX_PE34 NOISO GVPLSQVKSISGTVQDGTAETLPSSSNDKSPEIEKS--KDEA-QDNGAPVMPIITESFSL SORARGS_6034_PE1 NOISO GVPLSQVKSISGTAQVGNAETLSPGSSDKNPGAQKS--KGEA-QENGATIMPIITESFSL SPETRGS_4895_PE1 NOISO GVPLSQVKSISGTPQDGSAETLPPDSSDKNLVIQKS--KDET-QDNGATIMPIITESFSL TETNG1_PE265 NOISO ASPLSQIKGLPGLSKETES-----------------------KSDASAEVMPIITESFSL TUPGBGS_4719_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXX-XXXXXTIMPIITESFSL TURTR110299_PE1 NOISO GVPLSQVKSISGTAQDGNAETLPPGSSDKNLEIQKS--KDEA-QENGATIMPIITESFSL XENTR10_6_PE3 NOISO GIPLSQVKSISGGGGKDGSADASPNPDQKVLEPQKSTDSPSPSTAKIKAEMPEITESFLL MATCH CONSENSUS G?PLSQVK?ISG??????????????????????????????????????MPIITESFSL

AILMEGL192924_1_1_PE17 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSTNAVAQVQPTPGSVA ANOCA1303_PE6 NOISO CDKECDNTKITISDS----DD----DDDDVIFCSELVAPKEPK----AATPGQACSSSVG BOVINUN_004_305_PE1 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSTNTVAEVQPNPGSVA CALJAX_111_PE12 ENSCJAG00000004915 SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPAKETLPNNNTVAQVQSKPGPVA CALJAX_111_PE13 ISOFORMIN SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPAKETLPNNNTVAQVQSKPGPVA CALJAX_111_PE14 ISOFORMIN SAEDYEMKKIIVT---------------DVIFCSEILPAKETLPNNNTVAQVQSKPGPVA CANFAX_97_PE7 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKDTLPSTNAVAQVQPSPGSVA CAVPO69_1_PE1 NOISO SAEDYEMKKIIVTDS----DDD---DDDDVIFCSEILPAKEALPSNNAVTQGQPNQGPVA CHICK4_PE425 NOISO HGIAYETPKITVTDS----DD-----DDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASG DANRE14_36_PE22 NOISO SAEEFNMTGANT--------EKEDSDSDDVLFVSKTEAPQAQKTKISDVHKN-------- DASNOGS_6096_PE1 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSNNTVAQVQPNPGSVA ECHTEGS_7283_PE1 NOISO SAKDYETKKIIVTDS----DDDDNDNDDEVIFCSEILPAKESLPNS--TPQVQPNPGSVA ERIEUGS_7429_PE1 NOISO PAEDYETKKIIVTDS----DD----DDDDVIFCSEILPPKETLPSPNTVPQAQPPPGSVA FELCAGS_4068_PE1 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSTNAVTQVQPNPGSVA FUGRU5_1_PE78 ENSTRUG00000010561 SAEEFKQASQDE--------GHDDDSDSDVLFVSQTNSQDKVS-QKDSTDEV-------- FUGRU5_1_PE79 ISOFORMIN SAEEFKQASQDE--------GHDDDSDSDVLFVSQTNSQD-------------------- GASACGROUPIV_7_PE54 NOISO SAEEFNQTSKA---------TSDSDSESEVLFVSQTDAKTSAAKQAAKSGEV-------- GORGOX_121_PE11 ENSGGOG00000010306 SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVA GORGOX_121_PE12 ISOFORMIN SAEDYEMKKIIVT---------------DVIFCSEILPTKETLPSNNTVAQVQSNPGPVA HORSEX_98_PE2 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSTNAVAQVQPNPGAVA HSX_PE2147 NOISO SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVA LAMPAGS_2965_PE1 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSTNAVAQVQPNPGSVA LOXAF32_11_PE10 NOISO SAEDYETKKIIVTDS----DDD---DDDDVIFCSEILPAKEPLPNNNA--QVHPNPGSVA MACMUX_121_PE17 NOISO SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVA MONDOX_29_PE16 NOISO CAEDYETKKIGT----------DSDEDDDVIFCSEILPPKEGLPGSTSVAQVQPDPEPVA MOUSEX_PE465 ENSMUSG00000048047 SAEDNEMKKIIVTDS----DDD---DDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVA MOUSEX_PE466 ISOFORMIN SAEDNEMKKIIVTDS----DDD---DDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVA MOUSEX_PE467 ISOFORMIN SAEDNEMKKIIVTDS----DDD---DDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVA ORNANULTRA390_1_PE18 ISOFORMIN SNEDYETKKIIVTDS----DS----DDDDVIFCSEILPPKETLPSNDASPQAQPSPTSTA ORNANULTRA390_1_PE19 ENSOANG00000002588 SSEDYETKKIIVTDS----DS----DDDDVIFCSEILPPKETLPSNDASPQAQPSPTSTA ORYLA10_6_PE16 NOISO SSEEFNQNEKKA--------GKEEDSDCDVVFVSRTDAQTRAAGG--EVSEV-------- PANTRX_120_PE11 NOISO SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPTKETLPSNNTVTQVQSNPGPVA PIGX_97_PE8 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSNNAVAQAQPNPGSVA POEGU4A_10_PE20 NOISO HGIEYETTKITVSDS----DD----EDDDVIFCSEIVPPKECTKDKNAASQNQPCSSPAG PONPYX_120_PE11 NOISO SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPTKETLPSNNTGAQVQSNPGPVA PROCAGS_6305_PE1 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPNNNA--QVHANPGSVA PTEVA6684_PE1 NOISO SAEDYETKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSNSAVAQVQPNSGSVA RABITX_96_PE3 NOISO SAEDYEMKKIIVTDS----D------DDDVIFCSEVLPAKETLSNNNAVTQVQPNPGPVA RATX_PE34 NOISO SAEDYEMKKIIVTDS----DDD---DDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVA SORARGS_6034_PE1 NOISO SAEDFETKKIIVTDS----DED---DDDDIIFCSEVLPAKENLPNPSTAVPVQPSPDLVA SPETRGS_4895_PE1 NOISO SAEDYETKKIIVTDS----DDDD--DDDDVIFCSEILPAKETLPNNNAVTQVQPNTGPVA TETNG1_PE265 NOISO SAEEFKQTSGDE--------GPDEDSDSDVMFVSQTRSQSKG--HPDGADEV-------- TUPGBGS_4719_PE2 NOISO SAEDYEMKKIIVTDS----DDDD-DDDDDVIFCSEILPAKETLPSNNAVAQVQPNASPVA TURTR110299_PE1 NOISO SAEDYEMKKIIVTDS----DD----DDDDVIFCSEILPAKETLPSTNTVAEVQPNPGSVA XENTR10_6_PE3 NOISO SSDDYKDKKASDSKDQDSAKEEDDDDDDDVIFCSEIVSFKQPPTEKKEAAQSQMAPDNEQ MATCH . :::* *. . CONSENSUS SAED?E?KKI?V??????????????DDDVIFCSEI?P?KE???????????Q???????

AILMEGL192924_1_1_PE17 NOISO ISDVAPCASNNSPPLPNL--------------TPT-QKLPTSVNQAT-LSQTQGSEKLLV ANOCA1303_PE6 NOISO ASEQTNCSNNTSPQSVA-----------------A-SRLDSSAVQPN-PSEGQAPAEPSA BOVINUN_004_305_PE1 NOISO ISDDAPCVSNSSPPLTNI--------------TPT-QKLPTSVNQAT-LSQTQGSEKLLV CALJAX_111_PE12 ENSCJAG00000004915 ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV CALJAX_111_PE13 ISOFORMIN ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV CALJAX_111_PE14 ISOFORMIN ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV CANFAX_97_PE7 NOISO ISDVAPCTSNNSPPLPNL--------------TPT-QKLPTSVNQAT-LSQTQGSEKLLV CAVPO69_1_PE1 NOISO ISDVAPCASSNSPPLTSV--------------TPT-QKLPTPVNQAT-LSQTQESETLLV CHICK4_PE425 NOISO ASDQKSCGSGGSPLLTST--------------TST-QKLTSSANQLN-PNQTLSSAESLV DANRE14_36_PE22 NOISO -I--EGAPETKKQKVTNE---EGVA-S--KSSIPQEKKSSER-----------------N DASNOGS_6096_PE1 NOISO ISDVAPCAGSNSPPLTNI--------------TPT-QKLPTSVNQAT-LSQTQGSEKLLV ECHTEGS_7283_PE1 NOISO ISDVAPCASNESTPIASI--------------TPT-QKLMPSVNQVT-LSQTPGSETVLG ERIEUGS_7429_PE1 NOISO ISDVTPCASSSSPPLTNI--------------APA-QKLPTSVNQTT-LSQTQGSEKLLV FELCAGS_4068_PE1 NOISO ISDVAPGASNNSPPLPNV--------------TPT-QKLPTAVNQAT-LSQTQGSEKLLV FUGRU5_1_PE78 ENSTRUG00000010561 -IDVDSADTENVSSKQNDQSAQIAARP--PEKSPTPAKTPDS--------------ELPV FUGRU5_1_PE79 ISOFORMIN --------------KQNDQSAQIAARP--PEKSPTPAKTPDS--------------ELPV GASACGROUPIV_7_PE54 NOISO -IDLEAADLGKAAPKQNEDSNHTVAKQ--K---ETTLKMSPA--------------KPPS GORGOX_121_PE11 ENSGGOG00000010306 ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV GORGOX_121_PE12 ISOFORMIN ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV HORSEX_98_PE2 NOISO ISDVAPCVSNNSPPLTNI--------------TPT-QKLPTSANQAT-LSQTQGSEKLLV HSX_PE2147 NOISO ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV LAMPAGS_2965_PE1 NOISO ISDIAPCASNSSPPLTNI--------------TPT-QKLPTSVNQAT-LSQTQGSEKVLV LOXAF32_11_PE10 NOISO ISDVAPCASSNSPPLTNT--------------TPT-QKLPTSMNQVT-LSQTQGSEKVLV MACMUX_121_PE17 NOISO ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV MONDOX_29_PE16 NOISO YADK-ACGTSSSPPLTN---------------KPL-QTLATSVSQTV-PSQTRNSEETLK MOUSEX_PE465 ENSMUSG00000048047 ISEVTPCASNNSPPVTNI--------------TPT-Q-LPTPVNQAT-LSQTQGSEELLV MOUSEX_PE466 ISOFORMIN ISEVTPCASNNSPPVTNI--------------TPT-Q-LPTPVNQAT-LSQTQGSEELLV MOUSEX_PE467 ISOFORMIN ISEVTPCASNNSPPVTNI--------------TPT-Q-LPTPVNQAT-LSQTQGSEELLV ORNANULTRA390_1_PE18 ISOFORMIN AHDVAPCGSS---SLTNV--------------PPT-QKLTASGNQST-PSQTQDDGESLG ORNANULTRA390_1_PE19 ENSOANG00000002588 AHDVAPCGSS---SLTNV--------------PPT-QKLTASGNQST-PSQTQDDGESLG ORYLA10_6_PE16 NOISO -IDLDKLDVENASKVDGN------------------------------------------ PANTRX_120_PE11 NOISO ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV PIGX_97_PE8 NOISO ISDVAPCASSSSPPLTSI--------------TPP-QKLPTSVNQAT-LSQTQGSEKLLV POEGU4A_10_PE20 NOISO ASDQKSCGSGGSPHLTNT--------------TAA-QNLTLSATQLS-PSQAQSGAESFV PONPYX_120_PE11 NOISO ISDVAPSASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LNQTQGSEKLLV PROCAGS_6305_PE1 NOISO ISDVTPCASNDSPPLANT--------------TPT-QKLPTSVNQVT-LSQTQGSEKVLV PTEVA6684_PE1 NOISO ISDVAPCASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV RABITX_96_PE3 NOISO VSNAVPCTNNNSTPLTNT--------------TPT-QKFPTPVNQAT-LSQTQGSEKLLV RATX_PE34 NOISO ISEVTPCTSSNSPPVTNI--------------TPP-Q-LPTPVNQST-LSQAQGSEELLV SORARGS_6034_PE1 NOISO VSDVTPSASSKSPPLTNI--------------TPT-PKLPPPVNPTV-LNPAQGSEILLG SPETRGS_4895_PE1 NOISO ISDVAPCASNNSPPLTNI--------------TPT-QKLPIPVNQAT-LSQTQGSEQLLV TETNG1_PE265 NOISO -IDVDSE---KVPSKPDHQSDGGSVHP--GDRSPTPAKTLDA--------------KPPV TUPGBGS_4719_PE2 NOISO ISDVAPCASNNSPPLTNI--------------TPT-QKLPTPVNQAT-LSQTQGSEKLLV TURTR110299_PE1 NOISO ISDVAPCASNSSPPLTNI--------------TPT-QKLPTSVNQAT-LNQTQGSEKLLV XENTR10_6_PE3 NOISO VPEVKKVTPAGQVQITQNSLP-SSQQPSKNTTSSTPQKPTPPVNTNTSQNPPPPANGFLS MATCH CONSENSUS ??D????????S????N????????????????PT?QKL????NQ?????Q???????L?

AILMEGL192924_1_1_PE17 NOISO SSAPTHLTPNIILLNQTPLTTPPNVTSSLPNHMSPSINLLVQNQQ-TP-NSAVITGNKAN ANOCA1303_PE6 NOISO PSAPKAAAPNILT--------SPDVSSSHEIEVSPI---PEENQPPCHNDSLT--DMETN BOVINUN_004_305_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSSSLPNHMSPSINLLVQNQQ-PP-NSAVLPGNKAN CALJAX_111_PE12 ENSCJAG00000004915 SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQP-TP-NSAILTGNKAS CALJAX_111_PE13 ISOFORMIN SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQP-TP-NSAILTGNKAS CALJAX_111_PE14 ISOFORMIN SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQP-TP-NSAILTGNKAS CANFAX_97_PE7 NOISO SSAPTHLTPNIILLNQTPLTTPPNVTSSLPNHMSPSINLLVQNQQ-TP-NSAVLTGNKAN CAVPO69_1_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSPSVPNHMSSSINLLVQNQQ-TP-NSAVLTGKKAN CHICK4_PE425 NOISO PVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAV DANRE14_36_PE22 NOISO ASLQNNLDPD-----VVILSS-TENSSSILT--SPVGTG--SN----------------- DASNOGS_6096_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSSSLPNHMSPSINLLVQNQQ-PP-NSAVLKGNEAN ECHTEGS_7283_PE1 NOISO SSAPAHLTPNIILLNQAPLTAPPSVTSSLPTHMSPSINILVQNPQ-PP-NSAVLSGNGAH ERIEUGS_7429_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSSSVPNHMSPSISLLVQNPQ-AP-SSATLPGSKAN FELCAGS_4068_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSSSLPNHMSPSINLLVQNPQ-TP-NSAILTGSKAN FUGRU5_1_PE78 ENSTRUG00000010561 TPCQNPKLPD-----SSPLHS-PNSSFSN----TPSIID--SG----------------- FUGRU5_1_PE79 ISOFORMIN TPCQNPKLPD-----SSPLHS-PNSSFSN----TPSIID--SG----------------- GASACGROUPIV_7_PE54 NOISO VSCPVPSVPD-----GGPLLS-PDSGSDKPA--SPARVP--SR----------------- GORGOX_121_PE11 ENSGGOG00000010306 SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQ-TP-NSAILTGNKAN GORGOX_121_PE12 ISOFORMIN SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQ-TP-NSAILTGNKAN HORSEX_98_PE2 NOISO SSAPTHLTPNIILLNQASHTTPPNVSSSLPNHMSPSINLLVQNQP-TP-NSAVLTGNKAN HSX_PE2147 NOISO SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQ-TP-NSAILTGNKAN LAMPAGS_2965_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSSSLPNHMSPSINLLVQNQQ-PP-NSAVLTGNKAN LOXAF32_11_PE10 NOISO SSAPTHLTPNIILLNQTPLTTPPSVSSSLPNHMSPSLNILVQNQQ-PP-NSAVMTGNEAN MACMUX_121_PE17 NOISO SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHIPSSINLLVQNQQ-TP-NSAILTGNKAN MONDOX_29_PE16 NOISO SAAPKHLTPNIILLNQPSLNSMPS--SSHPSQMSPAVNLLVQNHPQIPNNATALPKHRTN MOUSEX_PE465 ENSMUSG00000048047 SSASTHLTPNIILLNQAPLTAPPSASSSLPNHMSSSVNVLVQNQQ-TP-NSAVLTGNKAE MOUSEX_PE466 ISOFORMIN SSASTHLTPNIILLNQAPLTAPPSASSSLPNHMSSSVNVLVQNQQ-TP-NSAVLTGNKAE MOUSEX_PE467 ISOFORMIN SSASTHLTPNIILLNQAPLTAPPSASSSLPNHMSSSVNVLVQNQQ-TP-NSAVLTGNKAE ORNANULTRA390_1_PE18 ISOFORMIN APAPKHLTPNVILLNQIQQSATPP------------------------------------ ORNANULTRA390_1_PE19 ENSOANG00000002588 APAPKHLTPNVILLNQSRSNSSPSDRSSRPNSLSPSVHLRVRGQQ-APDTVIALTGNEAN ORYLA10_6_PE16 NOISO -------ALG-----KGEPST-PTTNSSHSS--SPLVVS--SR----------------- PANTRX_120_PE11 NOISO SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQ-TP-NSAILTGNKAN PIGX_97_PE8 NOISO SSAPTHLTPNIILLNQTPLTNPPNVSSSLPNHMSPSINLLVPNQQ-PP-NNAVLTGNKAN POEGU4A_10_PE20 NOISO SATPQHFTPNIIVLNKPLLNSSLGASSLHQTHVTPTINLLEENQQPSNNGSVTEVEATAV PONPYX_120_PE11 NOISO SSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQ-TP-NSAILTGNKAN PROCAGS_6305_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSSALPNCMSPSINILVQNQQ-PP-NSAVVTGNEAN PTEVA6684_PE1 NOISO SSAPTHLTPNIILLNQTPLTTPPNVSPSLPNHMSPSINLLVQNQQ-TP-NSAVLTGNKAN RABITX_96_PE3 NOISO SSAPTHLTPNIIVLNQTPLTTPPNVSSSLPNHTSSSVNLLVQNQQ-TP-NSAALTGKKAS RATX_PE34 NOISO SSASTHLTPNIILLNQAPLTAPPSVSSSLPNHMSSSVNVLVQNQQ-AP-NSA-VTGNKAE SORARGS_6034_PE1 NOISO PSAPTHLTPDIILLNQTSLTTPPNVSSSLPNHMSPSINLLMPNQQ-PP-CSAALTGGKAP SPETRGS_4895_PE1 NOISO SSAPTHLTPNIILLNQAPLTTPPNVSSSLPNHMSSSINLLMQNQQ-TP-NSAVLTGNKAS TETNG1_PE265 NOISO GAAQSPSLPT-----GSPLRS-PTAASVA----LPPEST--RT----------------- TUPGBGS_4719_PE2 NOISO SSAPTHLTPNIILLNQTPLT-PPNVSSSLPNHMSSSISLLVQNQQ-TP-NSDALTENKAS TURTR110299_PE1 NOISO SSAPTHLTPNIILLNQTSLTTPPNVSSSLPNHMSPSINVLVQNQQ-PP-NNAVLTGNKAN XENTR10_6_PE3 NOISO PPAQKQATPNTVQDQHSQNVTSGN-------ALSQ-QNTLVDLSSPKPQQISAV------ MATCH CONSENSUS ??A??HLTPN?I?LN???L???P???SS??????????????N?????????????????

AILMEGL192924_1_1_PE17 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADIPPNATFDGSLVQKMQIPTLLQE ANOCA1303_PE6 NOISO AE--DEDEDVED-DDDILGASSPGSASSSSLPTIAAAATTSTTTDNTGLQKTQATSLLQK BOVINUN_004_305_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQAEIPPNTTFDGSLIQKMQIPTLLQE CALJAX_111_PE12 ENSCJAG00000004915 EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQSTSFDGSLIQKMQIPTLLQE CALJAX_111_PE13 ISOFORMIN EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQSTSFDGSLIQKMQIPTLLQE CALJAX_111_PE14 ISOFORMIN EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQSTSFDGSLIQKMQIPTLLQE CANFAX_97_PE7 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADIPQNATFDGSLVQKMQIPTLLQE CAVPO69_1_PE1 NOISO EEEEE--EIIDDDDDDTISSSPDSAVSNTSLV-PQADTSQNPTFDGSLIQKMQIPTFLQE CHICK4_PE425 NOISO DV-E---EVV-EDSDDVISSSSPSSVSNSSSV-QQPSVPKAAPSEGSGVQKKQVVTFPQE DANRE14_36_PE22 NOISO ------------------SNPKPPACPDSVPSDPQNVSLPSDNIEVLGVQKKKVLLEHSP DASNOGS_6096_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADVPQNTIFDGSLIQKMQIPTLPQE ECHTEGS_7283_PE1 NOISO EEEEE--EIIDD-DDGTISSSPDSAVSNTSLV-PQAAIPSNTTFDGSLVQKMPMPTLLHD ERIEUGS_7429_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQAEVPPNTTFDGALIQKMQIPTLLQE FELCAGS_4068_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQAEIPPNATFDGPLIQKMQVPTLLQE FUGRU5_1_PE78 ENSTRUG00000010561 ------------------SSSTPPAGPNTFTSKSPSASQLPEIRDVTGVHKKQISTTCQ- FUGRU5_1_PE79 ISOFORMIN ------------------SSSTPPAGPNTFTSKSPSASQLPEIRDVTGVHKKQISTTCQ- GASACGROUPIV_7_PE54 NOISO ------------------SAPTTPARSVNVTPEPPSASQSSENSGTTGVHQKQVVASSQ- GORGOX_121_PE11 ENSGGOG00000010306 EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTSFDGSLIQKMQIPTLLQE GORGOX_121_PE12 ISOFORMIN EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTSFDGSLIQKMQIPTLLQE HORSEX_98_PE2 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADIPQNTTFDGSLIQKMQIPTLLQE HSX_PE2147 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTSFDGSLIQKMQIPTLLQE LAMPAGS_2965_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADNPPNTTFDGSLIQKMQIPTLLQE LOXAF32_11_PE10 NOISO EEEEE--EMIDD-DDDTISSSPDSAVSNTSLV-PQADVPQNTTFDGSLIQKMPIPTLLQE MACMUX_121_PE17 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTSFDGSLIQKMQIPTLLQE MONDOX_29_PE16 NOISO VDMEA--EIIDD-DDDTISSSPDSGVSNTSLV-PHPDTQKNVSFNGSAIQSKQVSLFHQE MOUSEX_PE465 ENSMUSG00000048047 EE--E--EIIDD-DDDIISSSPDSAVSNTSLV-PQADNSKSTTLDGSLTQKMQIPVLPQE MOUSEX_PE466 ISOFORMIN EE--E--EIIDD-DDDIISSSPDSAVSNTSLV-PQADNSKSTTLDGSLTQKMQIPVLPQE MOUSEX_PE467 ISOFORMIN EE--E--EIIDD-DDDIISSSPDSAVSNTSLV-PQADNSKSTTLDGSLTQKMQIPVLPQE ORNANULTRA390_1_PE18 ISOFORMIN ------------------------------------------------------------ ORNANULTRA390_1_PE19 ENSOANG00000002588 EEEEEEDAMEDEDDDDIISSSPDSAVSNTSLV-PQSEVRKEPAFDGSGVQKKQISPLEQE ORYLA10_6_PE16 NOISO ------------------SAPSTPAGARSFTPEPSSSSQPFDNTDIMGVHKKQVSTLFQ- PANTRX_120_PE11 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTSFDGSLIQKMQIPTLLQE PIGX_97_PE8 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQAEIPQNTTFDGSLIQKMQVPTLLQE POEGU4A_10_PE20 NOISO DD-E---EVV-EDDVDIISSSSPGSVSSSSLV-QQSSVPKAGSTEGSGVQKKQVVTFSQE PONPYX_120_PE11 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTSFDGSLIQKMQIPTLLQE PROCAGS_6305_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADIPQNNTFDGSLIQKMPIPTLLQE PTEVA6684_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAISNTSLV-PQADIPQSTTFDGSLIQKMQIPTLLQE RABITX_96_PE3 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTTFDGSLVQKMQVPTLLQE RATX_PE34 NOISO EE--E--EILDD-DDDIISSSPDSAVSNTSLV-PQADASKSTTFDGSLTQKMQAPILPQE SORARGS_6034_PE1 NOISO EEEE---EIIDD-DDDTISSSPNSAVSNISLV-PQAGILPNDPFDGSLLQKMQLPSLLQE SPETRGS_4895_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTTFDGSLIQKMQIPTLLQE TETNG1_PE265 NOISO ------------------L--LPRRR--PGPTKSSAASQPPESRDIPGVHKKQISTSCQ- TUPGBGS_4719_PE2 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQADTSQNTTFDGSLVQKMQIPTLLQE TURTR110299_PE1 NOISO EEEEE--EIIDD-DDDTISSSPDSAVSNTSLV-PQAEIPPNTAFDGSLIQKMQIPTLLQE XENTR10_6_PE3 NOISO ---QPKTEVIVH-GN---GISPPS-SSVT-PLAQQPITPKHISFD--GVQKKQVVTFTQG MATCH CONSENSUS ???????E?????DDD?ISSS??SA?SNTSLV?PQ?????????DG???QK?Q?????Q?

AILMEGL192924_1_1_PE17 NOISO P----LSNSLKISDIITRNTN--DAGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI ANOCA1303_PE6 NOISO PVPQSNEFNIKISNVISASKKEAPPGVGPKHITEGQKTITLDTATEIDSLSTGCKVYANI BOVINUN_004_305_PE1 NOISO P----VSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI CALJAX_111_PE12 ENSCJAG00000004915 P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI CALJAX_111_PE13 ISOFORMIN P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI CALJAX_111_PE14 ISOFORMIN P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI CANFAX_97_PE7 NOISO P----LSNSLKISDIITRNTN--DAGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI CAVPO69_1_PE1 NOISO P----LSSSLKISDIITRNTN--DTGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI CHICK4_PE425 NOISO QSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANI DANRE14_36_PE22 NOISO D----HPGKITLSDVRSSCSSS-NGPTNVIPALSVKKTITLDKASEIDSLSPGCKVYANI DASNOGS_6096_PE1 NOISO P----LSISLKISDIITRNTN--DPGLGSKHLMEGQKIIXXXXXXXXXXXXXXXXXXXXX ECHTEGS_7283_PE1 NOISO P----LSSSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI ERIEUGS_7429_PE1 NOISO P----PSNSLKISDIITRSTN--GPGLGAKHLTEGQKIITLDTATEIEGLSTGCKVYANI FELCAGS_4068_PE1 NOISO P----LSNSLKISDIITRNTN--DAGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI FUGRU5_1_PE78 ENSTRUG00000010561 E----GNFKIMLKDVSEGPA---NHGDLPKSNVKAVKTVTLNAAAEIDSLSPGCKVYANI FUGRU5_1_PE79 ISOFORMIN A----------------------------------------------------------- GASACGROUPIV_7_PE54 NOISO H----GDSKIKLLDKANL-------TNSPKLTVAAKKTVTLNTTTEIDSISSGCKVYANI GORGOX_121_PE11 ENSGGOG00000010306 P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI GORGOX_121_PE12 ISOFORMIN P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI HORSEX_98_PE2 NOISO P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI HSX_PE2147 NOISO P----LSNSLKISDIITRNTN--DPGVGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI LAMPAGS_2965_PE1 NOISO P----LNNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI LOXAF32_11_PE10 NOISO P----LSNSLKISDIITRNIS--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI MACMUX_121_PE17 NOISO P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI MONDOX_29_PE16 NOISO P----LSNSLKISNVITESSK--DSGGGSKHVMEGQKIITLDTATEIEGLSTGCKVYANI MOUSEX_PE465 ENSMUSG00000048047 P----PSNSLKISDVITRNTN--DPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANI MOUSEX_PE466 ISOFORMIN P----PSNSLKISDVITRNTN--DPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANI MOUSEX_PE467 ISOFORMIN P----PSNSLKISDVITRNTN--DPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANI ORNANULTRA390_1_PE18 ISOFORMIN ------------------------------------------------------------ ORNANULTRA390_1_PE19 ENSOANG00000002588 LPSHPGEFKLKISDILTGNHK--DPGAVSKHMTEGQKIITLDTATEIEGLSTGCKVYANI ORYLA10_6_PE16 NOISO E----G------------------------------------------------------ PANTRX_120_PE11 NOISO P----LSNSLKISDIITRNTN--DPGVGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI PIGX_97_PE8 NOISO P----LSNSLKISDIITRNTN--DPGLGSKHLTEGQKIITLDTATEIEGLSTGCKVYANI POEGU4A_10_PE20 NOISO PPPKAGEFKIKISDVLSGNNKELSSGLTSRNVADGQKIITLDTATEIGGLSTGCKVYANI PONPYX_120_PE11 NOISO P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI PROCAGS_6305_PE1 NOISO P----VSNSLKISDVITRNTN--DTGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI PTEVA6684_PE1 NOISO P----LSNSLKISDIITRNTN--DPGLESKHLMEGQKIITLDTATEIEGLSTGCKVYANI RABITX_96_PE3 NOISO P----LSNSLNISDIITRFTN--DRGLGSKHLMEGQKIITLDTATEIEGLSNGCKIYANI RATX_PE34 NOISO P----PSNSLKISDVITRNTN--DPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANI SORARGS_6034_PE1 NOISO P----IS-TLKVSNVITRNIS--DSGLAVKHLSEGQKIITLDTATEIEGLSTGCKVYANI SPETRGS_4895_PE1 NOISO P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI TETNG1_PE265 NOISO E----GNFKITLKDVSEVPP---SPGRAAPPSVAAVKTVTLNAATEIDSFSTGCKVYANI TUPGBGS_4719_PE2 NOISO P----LSNSLKISDVITRNTN--DPGLGSKHLTEGQKIITLDTATEIEGLSTGCKVYANI TURTR110299_PE1 NOISO P----LSNSLKISDIITRNTN--DPGLGSKHLMEGQKIITLDTATEIEGLSTGCKVYANI XENTR10_6_PE3 NOISO SPSKPGEFKIKIADVVSGSSKDSHKDSEPRRIIDGKKIITLDTASEIEGLSTGCKVYANI MATCH CONSENSUS ??????????KISD???????????G???KH??EGQKIITLDTATEI?GLSTGCKVYANI

AILMEGL192924_1_1_PE17 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSSGETPNK-RMKVKHDDHYELIVDGR ANOCA1303_PE6 NOISO GEDTYDVVIPVKDEAD-GEVRL--D----DVPRTSGDDATDRKRLKVKHDDHYELIMDGK BOVINUN_004_305_PE1 NOISO GEDTYDIVIPVKDDPDEGEARL-GN----EIPKTPSSETANK-RMKVKHDDHYELIVDGR CALJAX_111_PE12 ENSCJAG00000004915 GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGSEMANK-RMKVKHDDHYELIVDGR CALJAX_111_PE13 ISOFORMIN GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGSEMANK-RMKVKHDDHYELIVDGR CALJAX_111_PE14 ISOFORMIN GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGSEMANK-RMKVKHDDHYELIVDGR CANFAX_97_PE7 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSSGEPANK-RMKVKHDDHYELIVDGR CAVPO69_1_PE1 NOISO GEDTYDIVIPVKDDPDEGEAKL-EN----EIPKTSGGESTGK-RMKVKHDDHYELIVDGR CHICK4_PE425 NOISO GEDTYDIVIPIKDDPEEGEAKP--N----EAPRTSDGDSTSRKRMKVKHDDHYELIVDGR DANRE14_36_PE22 NOISO GENTYDIV-PVKDDPGEGAAPGCKSQIQPDSPNTASLSPKSKKKFKPDQEDHYEIIMDGK DASNOGS_6096_PE1 NOISO XXXXXXXXXXX--XXXXXXXXXXXX----XXXXXXXXXXXXX-KRMVKHDDHYELIVDGR ECHTEGS_7283_PE1 NOISO GEDTYDIVIPVKDDPDEGEARL-ES----DMPKTSSSESANK-RMKVKHDDHYELIVDGR ERIEUGS_7429_PE1 NOISO GEDTYDIVIPVKDDPDEGEAKL-EN----EIAKTSGSETANK-RMKVKHDDHYELIVDGR FELCAGS_4068_PE1 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSSGETANK-RMKVK------------ FUGRU5_1_PE78 ENSTRUG00000010561 GTNTYDIV-PVKEDPDEGGSKSKPTDSTPASPKAS----PNRKRSKTELEDHYELIMDGK FUGRU5_1_PE79 ISOFORMIN ----------------------------------S----PNRKRSKTELEDHYELIMDGK GASACGROUPIV_7_PE54 NOISO GENTYDIV-PLKEDPGEGGSKANK-----ALPTGG----SNKKKPKTELEDHYELVMDGK GORGOX_121_PE11 ENSGGOG00000010306 GEDTYDIVIPVKDDPDEGEARL-EN----EIAKTSGSEMANK-RMKVKHDDHYELIVDGR GORGOX_121_PE12 ISOFORMIN GEDTYDIVIPVKDDPDEGEARL-EN----EIAKTSGSEMANK-RMKVKHDDHYELIVDGR HORSEX_98_PE2 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----ETPKTSSSETANK-RMKVKHDDHYELIVDGR HSX_PE2147 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGSEMANK-RMKVKHDDHYELIVDGR LAMPAGS_2965_PE1 NOISO GEDTYDIVIPVKDDPDEEA--RLEN----ELPKHLXXXXXXX-XXXXXXXXXXXXXXXXX LOXAF32_11_PE10 NOISO GEDTYDIVIPVKDDPDEGEARP-EN----DIPKTSGSEMANK-RMKVKHDDHYELIVDGR MACMUX_121_PE17 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGSEMANK-RMKVKHDDHYELIVDGR MONDOX_29_PE16 NOISO GEDTYDIVIPVKDDPDEKEAKH-DN----EVPKTSGDEPSNK-RVKVKHDDHYELIVDGR MOUSEX_PE465 ENSMUSG00000048047 GEDTYDIVIPVKDDPDGGEAKL-DN----ELPKTSGSEPPNK-RMKVKHDDHYELIVDGR MOUSEX_PE466 ISOFORMIN GEDTYDIVIPVKDDPDGGEAKL-DN----ELPKTSGSEPPNK-RMKVKHDDHYELIVDGR MOUSEX_PE467 ISOFORMIN GEDTYDIVIPVKDDPDGGEAKL-DN----ELPKTSGSEPPNK-RMKVKHDDHYELIVDGR ORNANULTRA390_1_PE18 ISOFORMIN -------------------------------------------WCPSLSDDHYELIVDGR ORNANULTRA390_1_PE19 ENSOANG00000002588 GEDTYDIVIPVKDDPDEGEAKL-DS----EVPRTSGDDPSNRKRMKVKHDDHYELIVDGR ORYLA10_6_PE16 NOISO ------------------------------------------------DVKHYEVVMDGK PANTRX_120_PE11 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGSEMANK-RMKVKHDDHYELIVDGR PIGX_97_PE8 NOISO GEDTYDIVIPVKDDPDEGEARLLRN----EIPKTSSSETANK-RMKVKHDDHYELIVDGR POEGU4A_10_PE20 NOISO GEDTYDIVIPVKGDSEEGEAKP--D----DTPKKSDDESPKGKRMKVKHDDHYELIVDGR PONPYX_120_PE11 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGSEMANK-RMKVKHDDHYELIVDGR PROCAGS_6305_PE1 NOISO GEDTYDIVIPVKDDPDEGEARL-ES----DIPKTSGNEMTNK-RTKVKHDDHYELIVDGR PTEVA6684_PE1 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSSSETANK-RMKVKHDDHYELIVDGR RABITX_96_PE3 NOISO GEDTYDIVIPVKDDPDEGESKP-EN----ETPKTSGNETANK-RMKVKHDDHYELIVDGR RATX_PE34 NOISO GEDTYDIVIPVKDDPDGGEAKL-EN----ELPKTSGSEPSNK-RMKVKHDDHYELIVDGR SORARGS_6034_PE1 NOISO GEDTYDIVIPVKDDPDEGEPRL-EN----ELPKTSTGETANK-RMKVKHDDHYELIVDGR SPETRGS_4895_PE1 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSGNESASK-RMKVKHDDHYELIVDGR TETNG1_PE265 NOISO GENTYDIV-PVKEDPGEGGSRSA--TAPPASPKAS----PNRKRSKAELEDHYELIMDGK TUPGBGS_4719_PE2 NOISO GEDTYDIVIPVKNDPDEGEARL-EN----EIPKISGSEMSNK-HMKVEHDDHYELIVDGR TURTR110299_PE1 NOISO GEDTYDIVIPVKDDPDEGEARL-EN----EIPKTSSSETANK-RMKVKHDDHYELIVDGR XENTR10_6_PE3 NOISO GEDTYDIVIPIKEDPEEGEAKLDLD----G--------LPNRKRMKMKHDDHYELIVDGR MATCH CONSENSUS GEDTYDIVIPVK?DP?EGE????????????P??S????????R?KVKHDDHYELIVDGR

AILMEGL192924_1_1_PE17 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR ANOCA1303_PE6 NOISO VYYICIVCRRSYVCLTSLRRHFNVHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR BOVINUN_004_305_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR CALJAX_111_PE12 ENSCJAG00000004915 VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR CALJAX_111_PE13 ISOFORMIN VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR CALJAX_111_PE14 ISOFORMIN VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR CANFAX_97_PE7 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR CAVPO69_1_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR CHICK4_PE425 NOISO VYYICIVCKRSYVCLTSLRRHFNVHS-WE-KKYPCRYCDKVFPLAEYRTKHEIHHTGERR DANRE14_36_PE22 NOISO TFFVCIVCKRPYVCLTSLRRHFNTHS-WE-RKYPCHYCNKVFALAEYRTKHEISHTGERR DASNOGS_6096_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR ECHTEGS_7283_PE1 NOISO IYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR ERIEUGS_7429_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR FELCAGS_4068_PE1 NOISO ------------------------------------------------------------ FUGRU5_1_PE78 ENSTRUG00000010561 TFYVCVVCKRPYVCLTSLRRHFNTHS-WE-KKYPCRYCDKVFALAEYRTKHELQHTGERR FUGRU5_1_PE79 ISOFORMIN TFYVCVVCKRPYVCLTSLRRHFNTHS-WE-KKYPCRYCDKVFALAEYRTKHELQHTGERR GASACGROUPIV_7_PE54 NOISO TFYVCVVCKRPYVCLTSLRRHFNTHS-WE-KQYPCHYCDKVFALAEYRTKHEIHHTGERR GORGOX_121_PE11 ENSGGOG00000010306 VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR GORGOX_121_PE12 ISOFORMIN VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR HORSEX_98_PE2 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR HSX_PE2147 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR LAMPAGS_2965_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX LOXAF32_11_PE10 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERS MACMUX_121_PE17 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR MONDOX_29_PE16 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR MOUSEX_PE465 ENSMUSG00000048047 VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYQCRYCDKVFPLAEYRTKHEIHHTGERR MOUSEX_PE466 ISOFORMIN VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYQCRYCDKVFPLAEYRTKHEIHHTGERR MOUSEX_PE467 ISOFORMIN VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYQCRYCDKVFPLAEYRTKHEIHHTGERR ORNANULTRA390_1_PE18 ISOFORMIN VYYICIVCKRSYVCLTSLRRHFNVHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR ORNANULTRA390_1_PE19 ENSOANG00000002588 VYYICIVCKRSYVCLTSLRRHFNVHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR ORYLA10_6_PE16 NOISO TFFVCVVCKRPYVCLTSLRRHFNTHS-WE-KKYPCRHCNKVFALAEYRTKHEILHTGERR PANTRX_120_PE11 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR PIGX_97_PE8 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR POEGU4A_10_PE20 NOISO VYYICMVCKRSYACLTSLRRHFNVHS-WE-KKYPCRYCDKVFALAEYRTKHELHHTGERR PONPYX_120_PE11 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR PROCAGS_6305_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR PTEVA6684_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR RABITX_96_PE3 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR RATX_PE34 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYQCRYCDKVFPLAEYRTKHEIHHTGERR SORARGS_6034_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR SPETRGS_4895_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR TETNG1_PE265 NOISO TFYVCVVCKRPYVCLTSLRRHFNTHS-WE-KKYPCRYCHKVFALAEYRTKHELQHTGERR TUPGBGS_4719_PE2 NOISO VYYICIICKMSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR TURTR110299_PE1 NOISO VYYICIVCKRSYVCLTSLRRHFNIHS-WE-KKYPCRYCEKVFPLAEYRTKHEIHHTGERR XENTR10_6_PE3 NOISO VYYICIVCKRSYVCLTSLRRHFNVHS-WE-KKYPCRYCERVFPLAEYRTKHEIHHTGERR MATCH CONSENSUS VYYICIVCKRSYVCLTSLRRHFN?HS?WE?KKYPCRYC?KVFPLAEYRTKHEIHHTGERR

AILMEGL192924_1_1_PE17 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD ANOCA1303_PE6 NOISO YQCLACGQCFINYQVMATHLRSVHSQDPSGE-------SKHYRLHPCRSLQIRNYAYISG BOVINUN_004_305_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD CALJAX_111_PE12 ENSCJAG00000004915 YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD CALJAX_111_PE13 ISOFORMIN YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD CALJAX_111_PE14 ISOFORMIN YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD CANFAX_97_PE7 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD CAVPO69_1_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCKSLQIRQYAYLSD CHICK4_PE425 NOISO YQCLTCGKSFINYQIMASHIRSVHSQDPSGD-------NKLYRLHPCKSLQIRQYAYISD DANRE14_36_PE22 NOISO YQCLLCNEMFLNYQILSTHCKQAHNQDPSGRKEKDDSANNLYRLLPCKTVQFKPYSFVSD DASNOGS_6096_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD ECHTEGS_7283_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------AKLYRLHPCRSLQIRQYAYLSD ERIEUGS_7429_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD FELCAGS_4068_PE1 NOISO ------------------------------------------------------------ FUGRU5_1_PE78 ENSTRUG00000010561 YQCLLCSGTFLNYQILATHCKSVHNQDPSGRKEKDDKNNNLYRLLPYKSTHVKPYSWGAD FUGRU5_1_PE79 ISOFORMIN YQCLLCSGTF-------------------------------------------------- GASACGROUPIV_7_PE54 NOISO YQCLVCNETFLNYQILATHCKQAHNQDPSGRKEKDEKDNNLYRLLPCKTVEMKPYSWSAD GORGOX_121_PE11 ENSGGOG00000010306 YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD GORGOX_121_PE12 ISOFORMIN YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD HORSEX_98_PE2 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD HSX_PE2147 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD LAMPAGS_2965_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXLYRLHPCRSLQIRQYAYLSD LOXAF32_11_PE10 NOISO SFKRGKKKK--------------------------------------------------- MACMUX_121_PE17 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD MONDOX_29_PE16 NOISO YQCLTCGKSFINYQFMSSHIKSVHSQDPSGD-------TKLYRLHPCRSLQIRQYAYLTD MOUSEX_PE465 ENSMUSG00000048047 YQCLTCGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCKSLQIRQYAYLSN MOUSEX_PE466 ISOFORMIN YQCLTCGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCKSLQIRQYAYLSN MOUSEX_PE467 ISOFORMIN YQCLTCGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCKSLQIRQYAYLSN ORNANULTRA390_1_PE18 ISOFORMIN YQCLTCGKAFINYQVMASHIRSVHSQD--------------------------------- ORNANULTRA390_1_PE19 ENSOANG00000002588 YQCLTCGKAFINYQVMASHIRSVHSQDPSGD-------TKLYRLHPCRSLQIRQYAYITD ORYLA10_6_PE16 NOISO YQCLLCNDTFLNYQLLSSHCKQAHNQDP-------------------------------- PANTRX_120_PE11 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD PIGX_97_PE8 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD POEGU4A_10_PE20 NOISO YQCLTCGKSFINYQITISHIRSVHSQDPSGD-------TKLYRLHPCRSLQIRQYAYISD PONPYX_120_PE11 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD PROCAGS_6305_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYSYLSD PTEVA6684_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD RABITX_96_PE3 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCKSLQIRQYSYLSD RATX_PE34 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCKSLQIRQYAYLSN SORARGS_6034_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSN SPETRGS_4895_PE1 NOISO YQCLACGKSFINYQFMSSHMKSVHSQDPSGD-------SKLYRLHPCKSLQIRQYAYLSD TETNG1_PE265 NOISO YQCLLCNGTFLNYQILATHCKSVHNQDPSGRKEKEDKNNHLYRLLPCKAPHAKPYPWSGE TUPGBGS_4719_PE2 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------AKLYRLHPCRSLQIRQYAYLSD TURTR110299_PE1 NOISO YQCLACGKSFINYQFMSSHIKSVHSQDPSGD-------SKLYRLHPCRSLQIRQYAYLSD XENTR10_6_PE3 NOISO YQCLTCGSSFINYQVMASHIRSVHSLDPSGD-------SKLYRLNPCKTLQIRQYAYVNN MATCH CONSENSUS YQCL?CG??FINYQ???SH??SVHSQDPSG??????????LYRL?PC?SLQIR?Y?Y???

AILMEGL192924_1_1_PE17 NOISO RSG-------------------AMPVMKDDAIGYKVDAGKDP---AVGAASAP-QNKPMT ANOCA1303_PE6 NOISO SSS------------------NNIPMANDNALVYPVAPAKDA---SSQEPAPNPPTKPMT BOVINUN_004_305_PE1 NOISO RSG-------------------TMPVMKDDGIGYKVDAGKEP---PVGTTSAP-QNKPMT CALJAX_111_PE12 ENSCJAG00000004915 RSS-------------------TMPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT CALJAX_111_PE13 ISOFORMIN RSS-------------------TMPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT CALJAX_111_PE14 ISOFORMIN RSS-------------------TMPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT CANFAX_97_PE7 NOISO RSG-------------------AMPVMKDDAIGYKVDAGKEP---AVGTTSTP-QNKPMT CAVPO69_1_PE1 NOISO RSS-------------------TMPGMKDGNIAYKVDARKEP---PVGTAS-T-QNKPVT CHICK4_PE425 NOISO RSS-------------------SLPVINENRIVYRVDAAKDG---TEGTTSNS-PGKQMS DANRE14_36_PE22 NOISO ESG-------------------GSPVIGEDGTIQYVNSEKEH---CTNQPLPSNQSKALN DASNOGS_6096_PE1 NOISO KSS-------------------TMPVMKDDGIGYKVDAGKEP---PVGTAST-PQSKPMT ECHTEGS_7283_PE1 NOISO RPS-------------------PMPVMKDDGIGYKVDAGKEP---PVGATS-A-PNKPMT ERIEUGS_7429_PE1 NOISO KSG-------------------AMPAMKDDGIGYKVDAGKET---PAGTPSTP-QNKPMT FELCAGS_4068_PE1 NOISO ------------------------------------------------------------ FUGRU5_1_PE78 ENSTRUG00000010561 G-S-------------------GFPVISEDGRVHHIS--SA-----GQDVQGSTQTNMLN FUGRU5_1_PE79 ISOFORMIN ------------------------------------------------------------ GASACGROUPIV_7_PE54 NOISO G-P-------------------GVPVISEDGSVHHIAAGAT-----GGDVRASTQSRMLN GORGOX_121_PE11 ENSGGOG00000010306 RSS-------------------TIPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT GORGOX_121_PE12 ISOFORMIN RSS-------------------TIPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT HORSEX_98_PE2 NOISO RSG-------------------TMPVMKDDGIGYKVDAGKEP---PVGTTSTP-QNKPMT HSX_PE2147 NOISO RSS-------------------TIPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT LAMPAGS_2965_PE1 NOISO RSG-------------------TMPVMKDDGVGYKVDAGKEP---PVGTTSTP-QNKPMT LOXAF32_11_PE10 NOISO ------------------------------------------------------------ MACMUX_121_PE17 NOISO RSS-------------------TMPAMKGDGIGYKVDTGKEP---PVGTTTST-QNKPMT MONDOX_29_PE16 NOISO RPR-------------------SIPVIKEDGIVYKVD-GKEP---SEGTATSTPQNKPMT MOUSEX_PE465 ENSMUSG00000048047 KSS-------------------AMPVMKDDAVGYKVDAGKEP---PVGTTSTPPQNKSTF MOUSEX_PE466 ISOFORMIN KSS-------------------AMPVMKDDAVGYKV------------------------ MOUSEX_PE467 ISOFORMIN KSS-------------------AMPVMKDDAVGYKVDAGKEP---PVGTTSTPPQNKSTF ORNANULTRA390_1_PE18 ISOFORMIN ------------------------------------------------------------ ORNANULTRA390_1_PE19 ENSOANG00000002588 RSS-------------------SIPVINEDGIVYHVDAGKEP---SEGTTSN-PSTKQMT ORYLA10_6_PE16 NOISO ------------------------------------------------------------ PANTRX_120_PE11 NOISO RSS-------------------TIPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT PIGX_97_PE8 NOISO RSG-------------------TMPVMKDDGIGYKVDAGKEP---PVGTTSAP-QNKPMT POEGU4A_10_PE20 NOISO RHS-------------------SVPGISDGGVVYRVGSGKDG---AEGAASNS-PAKQIT PONPYX_120_PE11 NOISO RSS-------------------TIPAMKDDGIGYKVDTGKEP---PVGTTTST-QNKPMT PROCAGS_6305_PE1 NOISO RSS-------------------TMPVMKDDGIGYKVDAGKEP---PVGTTS-T-QNKPMT PTEVA6684_PE1 NOISO RSG-------------------TVPVMKDDGIGYKVDAGKEP---PVGTTS-T-QNKPMT RABITX_96_PE3 NOISO RSS-------------------TVPVMKDDGIGYKVDAGKEP---PVETTSNT-QNKPMT RATX_PE34 NOISO KPS-------------------AMPVMKDDAVGYKVDAGKEP---PVGTTSAPPQNKSTF SORARGS_6034_PE1 NOISO RSG-------------------TMPGMKDDGVGYRVDAGREN---PVGTTST-PQNKPMT SPETRGS_4895_PE1 NOISO RSS-------------------TVPVMKDDGIGYKVDAGKEP---PVGTTS-T-QNKPMT TETNG1_PE265 NOISO G-P-------------------GFPVISEDGRVHHVG--PA-----GQEAQGSAPAAMLN TUPGBGS_4719_PE2 NOISO RSS-------------------TMPVMKDDGIGYKVDAGKEP---PVGTTS-TPQNKPMT TURTR110299_PE1 NOISO KSG-------------------TMPVMKDDGIGYKVDAGKEP---PVGTTSTP-QNKPMT XENTR10_6_PE3 NOISO SNNASVIHDGAINVPVITDGGINVPVINDGGIVYDIDPDKPQQPASEGSHAN-SAPKPVN MATCH CONSENSUS ????????????????????????P????????Y?V????????????????????K???

AILMEGL192924_1_1_PE17 NOISO WEDIFIQQENDS---------IFKQNVTDGSTEFEFIIPESY ANOCA1303_PE6 NOISO WDDIFVPQGNES---------LFKQNPSDGSTEFEFVIPESY BOVINUN_004_305_PE1 NOISO WEDIFIQQENDS---------MFKQNVTDGSTEFEFIIPESY CALJAX_111_PE12 ENSCJAG00000004915 WEDIFIQQENDS---------IFKQNVTDGSTEFEFIIPESY CALJAX_111_PE13 ISOFORMIN WEDIFIQQENDS---------IFKQNVTD