Alignment of the gene Family HOG000264957 of HOGENOM

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Isoforms are ON
ACYPI_11004_PE3 NOISO EIS------DPYLKYKFIVKKWENEFIKTNSRNPKKDDIKLAEQKVRYAYKMYWKIKTSL AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO ---------------------------------PPQEDVEAAPEETRALYREYRALKGAL ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_2_PE1395 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_3_PE1398 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_4_PE1398 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_5_PE1397 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_6_PE1398 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_7_PE1397 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_8_PE1398 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL ANOGA_9_PE1398 HAPLOTYPE -MEEDQAFRAKYQKCKYRVKQWEKEFRKKYGRIPSKLDIRESPSEIRNSYKLYYQLKTNL APIME_119_PE11 NOISO EILEDPVFKTEYQKYKIRVKLWESRFTAKHGRKPNKNDIKEADMKIKESYKMYWKLKTRA APIME_119_PE12 NOISO EILEDPVFKTEYQKYKIRVKLWESRFTAKHGRKPNKNDIKEADMKIKESYKMYWKLKTRA ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN --M------ERLRDVRELLQAWERAFRRQSGRRPGKEDVEAAPEETRALYREYRSLKKAL BOVIN14_1_PE18 ENSBTAG00000010276 --M------ERLRDVRELLQAWERAFRRQSGRRPGKEDVEAAPEETRALYREYRSLKKAL BOVIN14_1_PE19 ISOFORMIN --M------ERLRDVRELLQAWERAFRRQSGRRPGKEDVEAAPEETRALYREYRSLKKAL BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO --M------ERLLDLRERLQAWERAFRQQHGRRPSQDDVKAAPEETRALYREYRTLKRTV CANFA13_42_PE41 NOISO --M------ERLRDVRGRLQAWEQKFVRLVGAQTAKSDEGGDPEAWVS---------GNP CAVPO95_4_PE36 NOISO --M------DRLWNLRARLQEWERKFTRQHGRRPDQEDVEAAPEETRALYRKYRALKQSV CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO --MEDPVFRTKYHKYKYKVKLWEKEFRKKNGRIPSKHDIRDSPAVVRASYKMYYKLKTSL CULQU_602_PE10 NOISO --MEDPVFRTKYHKYKYKVKLWEKEFRKKNGRIPSKHDIRDSPADVRASYKMYYKLKTSL DANRE19_4_PE9 NOISO --M------DRYNDVKILLKKWEQSFFQTNNRKPNKDDIDKAPEETRQLYKEYRSLKVAK DASNOGS_5448_PE2 NOISO --M------ERLRDVRARLLAWERAFRRSHGRRPGQGDVXXXXXXXXXXXXXXXXXXXXX DIPORGS_5063_PE4 NOISO --M------ERLRDVRGRLQAWEREFARLHGRRPCQDDVEAAPEETRDLYREYRTLKQAV DROME3L_9_PE65 NOISO --MDDSVFKLKYQKYKLRVKVWEKDFKKKNGRVPSKYDIRDASQEIRDSYKMYYKLKTSF ECHTEGS_6465_PE2 NOISO --M------ERLRAVRTRLLTWERDFRRRHGRRPGQADVAVAPEETQALYREYA-LKQVL ERIEUGS_6628_PE4 NOISO --M------ERLRDVRTRLQEWERAFRQQRGRKPGQEDVAAAPEETRALYREYRALKGAL FELCAGS_5236_PE10 NOISO ------------------------------------------------------------ FUGRU37_1_PE108 ENSTRUG00000012749 --M------DRYNEVKVLLKNWEQEFVKEHRKKPTKEDIDQAPEETKGLYKEYRRLKQAK FUGRU37_1_PE109 ISOFORMIN --M------DRYNEVKVLLKNWEQEFVKEHRKKPTKEDIDQAPEETKGLYKEYRRLKQAK FUGRU37_1_PE110 ISOFORMIN --M------DRYNEVKVLLKNWEQEFVKEHRKKPTKEDIDQAPEETKGLYKEYRRLKQAK GASACGROUPIII_7_PE38 NOISO --M------DRYNEVKLQLKSWEQRFVKDHQRKPNKEDIDQAPEETRKLYKEYRGLKEAK GORGO8_151_PE6 NOISO --M------ERLRDVREQLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTT HORSE9_86_PE8 NOISO ------------------------------------------------------------ HS8_PE3578 ISOFORMIN --M------ERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTT HS8_PE3579 ENSG00000160957 --M------ERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTT LOXAF185_PE18 NOISO ------------------------------------------------------------ MACEUGS_7560_PE2 NOISO ------------------------------------------------LYREYRALRRGQ MACMU8_150_PE22 NOISO --M------ERLRDVRERLQAWERAFRRERGRRPSQDDVEAAPQETRALYREYRTLKRTV MAIZE_2_PE7014 NOISO ------------------------------------------------------------ MICMUGS_3858_PE24 NOISO --M------ERLRDVRERLQEWERAFGRLHGRRPGQDDVEAAPEETRALYREYSALKRVL MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN --M------ERYQEVRTLLKTWEKAFFQEHKRKPNKSDVESAPEETKELYREYRTLRKSQ MONDO3_446_PE29 ENSMODG00000011014 --M------ERYQEVRTLLKTWEKAFFQEHKRKPNKSDVESAPEETKELYREYRTLRKSQ MOUSE15_PE705 ENSMUSG00000033762 --M------ERLATVRARLQEWERAFARLHGRRPAKGDVEAAPEETRALYREYRNLKQAV MOUSE15_PE706 ISOFORMIN --M------ERLATVRARLQEWERAFARLHGRRPAKGDVEAAPEETRALYREYRNLKQAV MYOLUGS_4426_PE2 NOISO --M------ERLREVRALLQAWERAFRRQRGRRPVQEDVEAAPEETRALYREYRALKETL NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO --M------ERLWDVRLRLQAWEQAFRRERARRPGQEDVQAAPEEIRALYRQYRVLKKAV ORNANCONTIG341_PE6 ENSOANG00000003526 -------------------------------------DVEAAPEETKELYREYRVLKRAL ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO ---------------------------------------------------EYRA-KRIL PANTR8_151_PE26 NOISO --M------ERLRDVRERLQAWERAFRRQRGRRPSQEDVESAPEETRALYREYRTLKRTT PEDHC_890_PE62 NOISO ---------------------------------------------MRESYNKYFKIKTEL PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO --M------ERLRDIRERLQAWERAFRRQRGRRPGQEDVEAAPEETRALYREYRALKETL PIG4_1_PE7 NOISO --M------ERLRDIRERLQAWERAFRRQRGRRPGQEDVEAAPEETRALYREYRALKETL PONPY8_159_PE8 NOISO --M------ERLRDVRERLQAWERAFRQQRGRRPTQDDVEAAPEDTRALYREYRALKRTT POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO --M------ERLQGVRAQLQAWERAFRRRHGRRPDQEDVRAAPQETRALYREYRALKEAL RAT7_PE1328 ENSRNOG00000032446 --M------ERLATVRARLQDWERAFVRLHGRRPAKEDVEAAPEETRALYREYRNLKQAV RAT7_PE1329 ISOFORMIN --M------ERLATVRARLQDWERAFVRLHGRRPAKEDVEAAPEETRALYREYRNLKQAV SORARGS_5380_PE3 NOISO ------------------------------------------------------------ SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO --M------ERLRDVRTRLQEWERGFRRQHRRRAGQEDVEAAPEDVRALYRGYRALKV-- TARSYGS_5559_PE1 NOISO --M------ERLQDMRTRLQDWEQAFYRLHGRRPGQNDVEATTEEIRALYREYRILKRAL TETNG21RD_PE128 ENSTNIG00000017539 --M------DRYNELKVLLKQWEQEFVKEHRNKPTKEDIDQAPEETRNLYKEYRRLKNAK TETNG21RD_PE129 ISOFORMIN --M------DRYNELKVLLKQWEQEFVKEHRNKPTKEDIDQAPEETRNLYKEYRRLKNAK TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO LEKTLIGEVDDA--NDSTIDETLFL----SYINDQTESN--------------------K AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO GRAG------------------------------GIGPH--------------------S ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_2_PE1395 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_3_PE1398 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_4_PE1398 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_5_PE1397 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_6_PE1398 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_7_PE1397 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_8_PE1398 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D ANOGA_9_PE1398 HAPLOTYPE LKHTLLEALDDDDDFDGSLISQEAS-----F-SQDVSG---------------------D APIME_119_PE11 NOISO LEETLIDISFSDEVENNIPTKTTM------------------------------------ APIME_119_PE12 NOISO LEETLIDISFSDEVENNIPTKTTMCTSPKEIKDENKSLKDNNK------QIIENEKDKKD ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN GQAG------------------------------GVEPH--------------------G BOVIN14_1_PE18 ENSBTAG00000010276 GQAG------------------------------GVEPH--------------------G BOVIN14_1_PE19 ISOFORMIN GQAG------------------------------GVEPH--------------------G BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO RPSGG-----------------------------GGGPC--------------------S CANFA13_42_PE41 NOISO ASSG------------------------------HILGP--------------------G CAVPO95_4_PE36 NOISO GQRI------------------------------G-GPH--------------------S CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO LEDTLQDALDDDDDFDSSLVSQVES-----TLSQDCS----------------------- CULQU_602_PE10 NOISO LEDTLQDALDDDDDFDSSLVSQVES-----TLSQDCS----------------------- DANRE19_4_PE9 NOISO ERNDA-----------------------------VKESQ--------------------- DASNOGS_5448_PE2 NOISO XXXXX-----------------------------XXXXX--------------------X DIPORGS_5063_PE4 NOISO RQAC------------------------------G-AAR--------------------S DROME3L_9_PE65 NOISO LEETLNDVLSEDG-YDILEMSQASD-FGVSMLDQDVSLNEGPQLPLDISALVG-PQSSGN ECHTEGS_6465_PE2 NOISO GQADG-----------------------------SWLPD--------------------S ERIEUGS_6628_PE4 NOISO RHAV------------------------------S------------------------- FELCAGS_5236_PE10 NOISO ------------------------------------------------------------ FUGRU37_1_PE108 ENSTRUG00000012749 ENSCK-----------------------------DTVGR--------------------D FUGRU37_1_PE109 ISOFORMIN ENSWG-----------------------------GG------------------------ FUGRU37_1_PE110 ISOFORMIN ENSCK-----------------------------DTVGR--------------------D GASACGROUPIII_7_PE38 NOISO ENGST-----------------------------DGASG--------------------R GORGO8_151_PE6 NOISO GQT-------------------------------GGGPR--------------------S HORSE9_86_PE8 NOISO ------------------------------------------------------------ HS8_PE3578 ISOFORMIN GQA-------------------------------GGGLR--------------------S HS8_PE3579 ENSG00000160957 GQA-------------------------------GGGLR--------------------S LOXAF185_PE18 NOISO ------------------------------------------------------------ MACEUGS_7560_PE2 NOISO VSRL-------------------------------------------------------- MACMU8_150_PE22 NOISO GQA-------------------------------GGGPR--------------------S MAIZE_2_PE7014 NOISO ------------------------------------------------------------ MICMUGS_3858_PE24 NOISO SQADG-------------------------------GPF--------------------S MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN ESVG------------------------------LSQPS--------------------N MONDO3_446_PE29 ENSMODG00000011014 ESVG------------------------------LSQPS--------------------N MOUSE15_PE705 ENSMUSG00000033762 RQAD------------------------------D-RHR--------------------V MOUSE15_PE706 ISOFORMIN RQAD------------------------------D-RHR--------------------V MYOLUGS_4426_PE2 NOISO LPAS------------------------------SAGPR--------------------G NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO RQAGG-----------------------------P------------------------- ORNANCONTIG341_PE6 ENSOANG00000003526 ESTA------------------------------LADAG--------------------N ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO GQA-------------------------------GGGPR--------------------N PANTR8_151_PE26 NOISO GQA-------------------------------GGGPR--------------------S PEDHC_890_PE62 NOISO LASQILNEENGN--LNNLTQ---IC----DFNSTDNGKC--------------------D PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO GQAG------------------------------DVRPN--------------------S PIG4_1_PE7 NOISO GQAG------------------------------DVRPN--------------------S PONPY8_159_PE8 NOISO GQA-------------------------------GGGPR--------------------S POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO GQAG------------------------------DVGRR--------------------G RAT7_PE1328 ENSRNOG00000032446 SQAD------------------------------D-GHR--------------------V RAT7_PE1329 ISOFORMIN SQAD------------------------------D-GHR--------------------V SORARGS_5380_PE3 NOISO ------------------------------------------------------------ SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ------------------------------------------------------------ TARSYGS_5559_PE1 NOISO RQA-------------------------------GSGSR--------------------S TETNG21RD_PE128 ENSTNIG00000017539 ENNCH-----------------------------DTVSR--------------------R TETNG21RD_PE129 ISOFORMIN ENNCH-----------------------------DTVSR--------------------R TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO P-------------I-------------------------------NDDPPVDINKPSVW AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO P-------------K--RS----------LLAT---------------A--EEMQEPSCW ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_2_PE1395 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_3_PE1398 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_4_PE1398 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_5_PE1397 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_6_PE1398 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_7_PE1397 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_8_PE1398 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW ANOGA_9_PE1398 HAPLOTYPE VSGL-LLSSGTI--LNDSALLERSSSMSSLLTKPI--ATAQPSDTHFEAEKLDQHNLVAW APIME_119_PE11 NOISO ------------------------------------------------------------ APIME_119_PE12 NOISO MENT---NEKDVKNTNLQEIENMKKDTENIDPEKYQNQCQNQCNNVTIDEKECKNVKDVW ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN S-------------G--QS----------LPVA---------------A--EQMLEPSCW BOVIN14_1_PE18 ENSBTAG00000010276 S-------------G--QS----------LPVA---------------A--EQMLEPSCW BOVIN14_1_PE19 ISOFORMIN S-------------G--QS----------LPVA---------------A--EQMLEPSCW BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO --------------P--EL----------LPAA---------------A--GEAPEPHCW CANFA13_42_PE41 NOISO G-------------G--SD----------ARRV---------------S--PQMQEPSCW CAVPO95_4_PE36 NOISO H-------------N--QS----------LSAA---------------A--QEAPEPGCW CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO -------FTGSF--SNLSELRDSNVSISALLTDQI--EG---KVTEFVAEEESELNAKAW CULQU_602_PE10 NOISO -------FTGSF--SNLSELRDSNVSISALLTDQI--EG---KVTEFVAEEESELNAKAW DANRE19_4_PE9 NOISO -----------------------------TKPP---------------ESQSSTDGSGCW DASNOGS_5448_PE2 NOISO X-------------X--XX-----------XXX---------------------XXXXXX DIPORGS_5063_PE4 NOISO S-------------G--PP----------LPAV---------------T--QEAPEPSCW DROME3L_9_PE65 NOISO LEEIPQSVEGSF--SNLIDLPNRQVLTN-LVN-----RDENHVIRKFEAVEELPINQNAW ECHTEGS_6465_PE2 NOISO E-------------Q--------------TPEA---------------AQ-----EXXXX ERIEUGS_6628_PE4 NOISO G-------------P--SS----------LPAA---------------A--EEVSEPSCW FELCAGS_5236_PE10 NOISO -----------------------------------------------------VPEPSCS FUGRU37_1_PE108 ENSTRUG00000012749 Q-----------------S----------GDAPEA---T----TALKITACRSVQEPESW FUGRU37_1_PE109 ISOFORMIN --------------------------------------------EDQITACRSVQEPESW FUGRU37_1_PE110 ISOFORMIN Q-----------------S----------GDAPEA---T----TAL--------KEPESW GASACGROUPIII_7_PE38 NOISO A-------------E--QS----------TSTAGI---K---TVQKKINKHRRSKEADCW GORGO8_151_PE6 NOISO --------------S--ES----------LPAA---------------A--EEAPEPRCW HORSE9_86_PE8 NOISO ----------------------------------------------------QALEPSCW HS8_PE3578 ISOFORMIN --------------S--ES----------LPAA---------------A--EEAPEPRCW HS8_PE3579 ENSG00000160957 --------------S--ES----------LPAA---------------A--EEAPEPRCW LOXAF185_PE18 NOISO -------------------------------------------------------EPTCW MACEUGS_7560_PE2 NOISO -------------------------------------------------Y--SAPELDCW MACMU8_150_PE22 NOISO --------------S--EL----------LPVA---------------V--EEVSRPRHP MAIZE_2_PE7014 NOISO ------------------------------------------------------MGNLCW MICMUGS_3858_PE24 NOISO P-------------E--QS----------LSAA---------------A--EEAPENSCW MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN S-------------G--QQ----------DPAV---------------E---QTPELDFW MONDO3_446_PE29 ENSMODG00000011014 S-------------G--QQ----------DPAV---------------EQ--QTPELDFW MOUSE15_PE705 ENSMUSG00000033762 L-------------E--QS----------LAEA---------------A--EEAQEPSCW MOUSE15_PE706 ISOFORMIN L-------------E--QS----------LAEA---------------A--EEAQEPSCW MYOLUGS_4426_PE2 NOISO P-------------V--QA----------PPEA---------------A--EEVPEPSCW NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ------------------------------QAE---------------A--QEDPESSCW ORNANCONTIG341_PE6 ENSOANG00000003526 P-------------E--QP----------SPAL---------------EQENKATEPGCW ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO P-------------D--PS----------LPTE---------------A--EEALESNCW PANTR8_151_PE26 NOISO --------------S--ES----------LPAA---------------A--EEAPEPRCW PEDHC_890_PE62 NOISO L-------------NNESK----------KDNCQL---NTHDKNVNNSNESINKIDPKTW PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO L-------------G--RS----------LSAA---------------A--EETLEPSCW PIG4_1_PE7 NOISO L-------------G--RS----------LSAA---------------A--EETLEPSCW PONPY8_159_PE8 NOISO --------------S--ES----------LPAA---------------A--EEAPESHCW POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO P-------------V--QS----------LPAA---------------A--EEIPELGCW RAT7_PE1328 ENSRNOG00000032446 Q-------------K--QS----------LAKA---------------A--EEEQEPSCW RAT7_PE1329 ISOFORMIN Q-------------K--QS----------LAKA---------------A--EEEQEPSCW SORARGS_5380_PE3 NOISO ------------------------------------------------------------ SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ------------------------------------------------------LEDSCW TARSYGS_5559_PE1 NOISO P-------------D--QS----------LPAT---------------T--EEEPEPSCW TETNG21RD_PE128 ENSTNIG00000017539 T-------------D--QS----------KDKPE----E----TVNKIPACRSLQEPECW TETNG21RD_PE129 ISOFORMIN T-------------D--QS----------KDKPE----E----TVNKIPACRSLQEPECW TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO GKHLNNKPKTEIPTIVKPIE----NNISVKFSKKLFD-GCDF-----------KKRNPRK AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO GPHLNRAATHSPHPTVS---GPSPVGSVPDYGKRLKA-NLKA-TLQGGPALGRIPRTPRR ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_2_PE1395 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_3_PE1398 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_4_PE1398 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_5_PE1397 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_6_PE1398 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_7_PE1397 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_8_PE1398 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK ANOGA_9_PE1398 HAPLOTYPE QGEKSRKAVQST---------KPAEPIEPPKPVTLK---G--ITLLPKSTALIPKRNPRK APIME_119_PE11 NOISO ------------------------------------------------------------ APIME_119_PE12 NOISO GNHLQRNNEKMPKKKES---------LLIGKSSSFQ------LSQNKFTNSNFTKRNPRK ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN GHHLNRAATQSPHPP-S---RWSPQESAQDYGKRLKA-NLKG-SLQARSTLGRIPRLAQR BOVIN14_1_PE18 ENSBTAG00000010276 GHHLNRAATQSPHPP-S---RWSPQESAQDYGKRLKA-NLKG-SLQARSTLGRIPRLAQR BOVIN14_1_PE19 ISOFORMIN GHHLNRAATQSPHPP-S---RWSPQESAQDYGKRLKA-NLKG-SLQARSTLGRIPRLAQR BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO GPHLNRAATQSPQPT-P---GRSCQGSFQDYGQRLKA-NLKG-TLQASPDLGHRPWPLGR CANFA13_42_PE41 NOISO GPHLSRAATRRPHAAGY---APGSAGAVADYGARLKA-NLRA-TRQAGPALGGIPRPPRR CAVPO95_4_PE36 NOISO GSHLNRSATQSPQPT-P---VLSPQGSAQNYGKRLKA-NLKA-TLQAEPTLGCRRQPPGR CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO GKELNRKKTVVEKE-----S-KGSNVL------VMN-------KLMMDASTVVPKRNPRK CULQU_602_PE10 NOISO GKELNRKKSVVEKE-----S-KVGNVLVKPKPKVMN-------KLMMDASTVVPKRNPRK DANRE19_4_PE9 NOISO GSHLNRKNLPVALPKLSSDDKETLKASAQYFGMKLKN-NLGGLTK-ERSFSLKKAATPRR DASNOGS_5448_PE2 NOISO XXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXTPR DIPORGS_5063_PE4 NOISO GPHLNRAATQSPQLTVA---QSRWASSVQDYGKRLKA-NLKDTTLQIGPALGRRFQSSQR DROME3L_9_PE65 NOISO GLNVSKKPPAPPQPVEASKS-APGHGKQPKAGASLKP-SL--SAKLFQSSRGFAKRNPRK ECHTEGS_6465_PE2 NOISO XXXXXX------------------------X-XXXXX-XXXX-----------X------ ERIEUGS_6628_PE4 NOISO GTHLNRAATQSPGPT-P---D-PGQKSLQDYGKRLKA-NLKG-ALQXXXXXXXXXXXXXX FELCAGS_5236_PE10 NOISO GPHLNRAATHSRHPPLS---GPSRPGSVRDYGERLKA-NLKG-TLQAGPALSRIPRTPRR FUGRU37_1_PE108 ENSTRUG00000012749 GAHLNRSAQPTPPPRLTSQERDSLKASAQYFGLKLKS-NLALLTK-DRPLSHKKSFHPGR FUGRU37_1_PE109 ISOFORMIN GAHLNRSAQPTPPPRLTSQ------ASAQYFGLKLKS-NLALLTK-DRPLSHKKSFHPGR FUGRU37_1_PE110 ISOFORMIN GAHLNRSAQPTPPPRLTSQERDSLKASAQYFGLKLKS-NLALLT------------KPGR GASACGROUPIII_7_PE38 NOISO GSHLNRGSLPTSSPRLTPEDRGSLMASAQYYGLKLKN-NLATLCK-ERPLSLKKPVRPGR GORGO8_151_PE6 NOISO GPHLNRAATKSPQPT-P---GRSCQGSVPDYGQRLKA-NLKG-TLQAGPALGRRPWPLGR HORSE9_86_PE8 NOISO GSHLNRAATQSPHPT-P---GPSPQASVQDYGKRLKA-NLKG-ALQAGPALGHTRRPPRR HS8_PE3578 ISOFORMIN GPHLNRAATKSPQST-P---GRSRQGSVPDYGQRLKA-NLKG-TLQAGPALGRRPWPLGR HS8_PE3579 ENSG00000160957 GPHLNRAATKSPQST-P---GRSRQGSVPDYGQRLKA-NLKG-TLQAGPALGRRPWPLGR LOXAF185_PE18 NOISO GPHLNRAVRQSPHPT-P---APSTQRSVPDYGKRLKA-NLKG-TLQAEPALGHVPRAPRR MACEUGS_7560_PE2 NOISO GAHLNRNV-KPPLPT-P---PALLQEPLQCYRMKLKS-NLKA-ALQAGSSSDRIPRLPRR MACMU8_150_PE22 NOISO SL--LPLSCLAEWQE-P---RS--RGQASVGTQAVSA-AILF-PSQAGPALGRRPWPLGR MAIZE_2_PE7014 NOISO STNRERWRRTAPSPSVPACSDLPAAVS--SFADAFVDFAVSDIFFPTFPSSSSLPPRPKT MICMUGS_3858_PE24 NOISO GPHLNRAATKSPHPA-P---EQSSGGSVQDYGKRLKA-NLKG-TLQAGPALVRISWPPRR MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN GAHLNRNMTKPPLPT-Q---TAILQVPSQCYGKKLKS-NLKA-ALQVGPSSGRIPRLPCR MONDO3_446_PE29 ENSMODG00000011014 GAHLNRNMTKPPLPT-Q---TAILQVPSQCYGKKLKS-NLKA-ALQVGPSSGRIPRLPCR MOUSE15_PE705 ENSMUSG00000033762 GPHLSRAATQNTQSM-P---KQSLLSSVQDYGKRLKA-NLKN-TTQTGPTQSRKLQLQKR MOUSE15_PE706 ISOFORMIN GPHLSRAATQNTQSM-P---KQSLLSSVQDYGKRLKA-NLKN-TTQTGPTQSRKLQLQKR MYOLUGS_4426_PE2 NOISO GSHLNRAVTQSLPAA-A---GPSPRGSVPDYGKRLKA-NLKD-ALQAGPALRRIPRPPQR NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO GSHLNRSVAGSSRPT-S---GQKPLASGQDYGKRLKA-NLQV-KVRXXXXXXXXXXXXXX ORNANCONTIG341_PE6 ENSOANG00000003526 GAHLNRNAVGIR--------EQTLGSSVPYFGRKLKS-NLKA-VIRVSVQGDSSESRSR- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO GPHLNRAAARSPEPE-P---ARRCRGLVQDYGGRLKA-NLRG-ALKAGS----LSPPPQR PANTR8_151_PE26 NOISO GPHLNRAATKSPQPT-P---GRSCQGSVPDYGQRLKA-NLKG-TLQAGPALGRRPWPLGR PEDHC_890_PE62 NOISO GENLNVPKENKKPKI-EKCNSMSVLSQKLFKGSKF------------------NKRNPRK PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO GPHLNRAATQTPHST-S---RLIPQGSVQDYGKRLKA-NLKD-SLQTGPALGRVPRLERT PIG4_1_PE7 NOISO GPHLNRAATQTPHST-S---RLIPQGSVQDYGKRLKA-NLKD-SLQTGPALGRVPRLERT PONPY8_159_PE8 NOISO GPHLNRAATQSPQPT-P---GRSCQGSVPDYGQRLKA-NLKG-NLQAGPALGRRPWPLGR POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO GSHLNRAATQSSHPS-P---EQSSRGSAQDYGERIAN---LG-ALQAGPALGRIPRPPRR RAT7_PE1328 ENSRNOG00000032446 GSHLNRAATQNTQSI-P---KQSPLSSIQDYGKRLKA-NLKN-TLQGGPTLSRKLQHQKR RAT7_PE1329 ISOFORMIN GSHLNRAATQNTQSI-P---KQSPLSSIQDYGKRLKA-NLKN-TLQGGPTLSRKLQHQKR SORARGS_5380_PE3 NOISO ----------------------------------------------ARPAVGHQSLSPPG SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO GPHLNRAATQSPQPT-P---QMSPRGSVQDYGKRLKA-NLKV-ILQAEPTLGRRLQPPRR TARSYGS_5559_PE1 NOISO GPHLNRAVTQSPQPA-P---GHSART-----------------------TTGRIPWLPVP TETNG21RD_PE128 ENSTNIG00000017539 GKHLNRSAQPTPPPRLTSQERDGLRASAQYYGLKLKS-NLASLSK-DRPFSLKKSFLPGR TETNG21RD_PE129 ISOFORMIN GKHLNRSAQPTPPPRLTSQERDGLRASAQYYGLKLKS-NLASLSK-DRPFSLKKSFLPGR TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ----------------------------------------------ERPVSLKKSFTPRS MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO SIVKKKTSELD---------CSQN------------------------------VSECIT AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO -PSS-KTPSLG------------------------------------------------- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_2_PE1395 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_3_PE1398 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_4_PE1398 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_5_PE1397 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_6_PE1398 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_7_PE1397 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_8_PE1398 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ ANOGA_9_PE1398 HAPLOTYPE -SISR----NSFGP-------SSQGSSTNG-T----APKMVL------------------ APIME_119_PE11 NOISO ------------------------------------------------------------ APIME_119_PE12 NOISO -SLSATKIKTKTEK-------DNDIISNALEQ----NTNKEL------------------ ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN -SSS-KIPSPE------------------------------------------------- BOVIN14_1_PE18 ENSBTAG00000010276 -SSS-KIPSPE------------------------------------------------- BOVIN14_1_PE19 ISOFORMIN -SSS-KIPSPE------------------------------------------------- BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO -SSS-KTPTPK------------------------------------------------- CANFA13_42_PE41 NOISO -LSS-EMPFPG------------------------------------------------- CAVPO95_4_PE36 NOISO -FLS-KKPTLK------------------------------------------------- CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO -SLSSRLSSSSFAS-------TSGLNSSSG-S----SWKDTL------------------ CULQU_602_PE10 NOISO -SLSSRLSSSSFAS-------TSALNSSSG-S----SWKDTL------------------ DANRE19_4_PE9 NOISO TPQK-LIKDTVDSNAAA----------TD--VESHTPKPA-------------------- DASNOGS_5448_PE2 NOISO -PRA-PSETPG------------------------------------------------- DIPORGS_5063_PE4 NOISO -PLS-KVPTPR------------------------------------------------- DROME3L_9_PE65 NOISO -PLSRCVSSSSSTT-------S---LSSVP-T----DHHEEL------------------ ECHTEGS_6465_PE2 NOISO --X--XX-XXX------------------------------------------------- ERIEUGS_6628_PE4 NOISO -XXX-XXXXXX------------------------------------------------- FELCAGS_5236_PE10 NOISO -PSS-EMPTPR------------------------------------------------- FUGRU37_1_PE108 ENSTRUG00000012749 VPLN-SLKVEHGQ-A------SQGTAATT--IDPLSPHHLSL--KLQVTIMQNK--EKLN FUGRU37_1_PE109 ISOFORMIN VPLN-SLKVEHGQ-A------SQGTAATT--IDPLSPQ---------------------- FUGRU37_1_PE110 ISOFORMIN VPLN-SLKVEHGQ-A------SQGTAATT--IDPLSPQKSV------------------- GASACGROUPIII_7_PE38 NOISO LPLN-SVKDGQRGQSNSSVAAAGQIASCNPKSSPLTPSKKVLGKKLSSLSAMHYLQIALF GORGO8_151_PE6 NOISO -SSS-KTSTPK------------------------------------------------- HORSE9_86_PE8 NOISO -PSS-KMLSSG------------------------------------------------- HS8_PE3578 ISOFORMIN -ASS-KASTPK------------------------------------------------- HS8_PE3579 ENSG00000160957 -ASS-KASTPK------------------------------------------------- LOXAF185_PE18 NOISO -PSS-ETPALR------------------------------------------------- MACEUGS_7560_PE2 NOISO -AAK-ES-SPK------------------------------------------------- MACMU8_150_PE22 NOISO -SSS-KTPTPN------------------------------------------------- MAIZE_2_PE7014 NOISO -PTT-FLPSPSRLV------AIGDLH-------------GDLPKSLSV------------ MICMUGS_3858_PE24 NOISO -PTS-KITTPK------------------------------------------------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN -QQP-KT-CPS------------------------------------------------- MONDO3_446_PE29 ENSMODG00000011014 -QQP-KT-CPS------------------------------------------------- MOUSE15_PE705 ENSMUSG00000033762 -SLS-TVPAPR------------------------------------------------- MOUSE15_PE706 ISOFORMIN -SLS-TVPAPR------------------------------------------------- MYOLUGS_4426_PE2 NOISO -PPP-TVPSPG------------------------------------------------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO -XXX-XXXXXX------------------------------------------------- ORNANCONTIG341_PE6 ENSOANG00000003526 --SQ-KT-APS------------------------------------------------- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO -PAS-RTTSPK------------------------------------------------- PANTR8_151_PE26 NOISO -ASS-KASTPK------------------------------------------------- PEDHC_890_PE62 NOISO KPSFNKTLSTSSLQENS------TLETTNLNS---------------------------S PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO -PFS-KKSSPG------------------------------------------------- PIG4_1_PE7 NOISO -PFS-KKSSPG------------------------------------------------- PONPY8_159_PE8 NOISO -SSS-KTPTPK------------------------------------------------- POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO -TP--SMPSTG------------------------------------------------- RAT7_PE1328 ENSRNOG00000032446 -SLS-IVPTSR------------------------------------------------- RAT7_PE1329 ISOFORMIN -SLS-IVPTSR------------------------------------------------- SORARGS_5380_PE3 NOISO -TSS-KLPSPE------------------------------------------------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO -PLS-KMPTTG------------------------------------------------- TARSYGS_5559_PE1 NOISO -SS--KMP-TS------------------------------------------------- TETNG21RD_PE128 ENSTNIG00000017539 VPLN-SWKDTQSGQASSPIGASGKTAATS--VNPFSPQYNSM--FIVQLFSQSYSSKCVY TETNG21RD_PE129 ISOFORMIN VPLN-SWKDTQSGQASSPIGASGKTAATS--VNPFSPQYNSM--FIVQLFSQSYSSKCVY TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO RPAI-GSPDVKTRNHLA------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO NITSNDS-------------------------------NVQEDS-----AFHDDSNLSVI AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO ----------------------------PPGGEAV--RIFPEVV-----S---------- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_2_PE1395 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_3_PE1398 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_4_PE1398 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_5_PE1397 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_6_PE1398 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_7_PE1397 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_8_PE1398 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- ANOGA_9_PE1398 HAPLOTYPE --------------PDL-------------------------ET-----LLTAKSKEI-- APIME_119_PE11 NOISO ------------------------------------------------------------ APIME_119_PE12 NOISO --------------NN-----------------------------------KDNSNII-- ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN ----------------------------PSGTAAA--PISPENV-----N---------- BOVIN14_1_PE18 ENSBTAG00000010276 ----------------------------PSGTAAA--PISPENV-----N---------- BOVIN14_1_PE19 ISOFORMIN ----------------------------PSGTAAA--PISPENV-----N---------- BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO ----------------------------LPGTGPA--PTFAEKV-----S---------- CANFA13_42_PE41 NOISO ----------------------------PPDAGAA--PVSAE-V-----S---------- CAVPO95_4_PE36 NOISO ----------------------------TLSPGIP--PTSPEEL-----S---------- CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO --------------PDL-------------------------ET-----LLNEKSKQV-- CULQU_602_PE10 NOISO --------------PDL-------------------------ET-----LLNEKSKQV-- DANRE19_4_PE9 NOISO ---NTCP-D----------------------PSAA--PVQAAKM-----DFEDDPSDP-- DASNOGS_5448_PE2 NOISO ----------------------------TPGAAAA--PTSPEEP-----R---------- DIPORGS_5063_PE4 NOISO ----------------------------PPDAKTT--STHADEI-----G---------- DROME3L_9_PE65 NOISO --------------LDF-------------------------ET-----ILIRKAQEY-- ECHTEGS_6465_PE2 NOISO -------------------------------XXXX--X---------------------- ERIEUGS_6628_PE4 NOISO ----------------------------XXXXXXX--XXXXXXX-----X---------- FELCAGS_5236_PE10 NOISO ----------------------------PPGAGAA--LISPEEV-----S---------- FUGRU37_1_PE108 ENSTRUG00000012749 NTSSFCP-FYRNAAAS---LAPGTDQPLASGDQYK--PFDPVSD-----SFDDSFHTN-- FUGRU37_1_PE109 ISOFORMIN -----------NAAAS---LAPGTDQPLASGDQYK--PFDPVSD-----SFDDSFHTN-- FUGRU37_1_PE110 ISOFORMIN --------CVGNAAAS---LAPGTDQPLARSTGFQ--RTR-------------------- GASACGROUPIII_7_PE38 NOISO SLLNTFPSPWGHVCRRLTS--GLRSLKVEPEESFQ--PFEPLRD-----SSEELAGAASG GORGO8_151_PE6 NOISO ----------------------------PPGTGPV--PSFAEKV-----S---------- HORSE9_86_PE8 NOISO ----------------------------LPAAGAA--LIAPEEV-----S---------- HS8_PE3578 ISOFORMIN ----------------------------PPGTGPV--PSFAEKV-----S---------- HS8_PE3579 ENSG00000160957 ----------------------------PPGTGPV--PSFAEKV-----S---------- LOXAF185_PE18 NOISO ----------------------------LPDTGAT--LTSPG-L-----S---------- MACEUGS_7560_PE2 NOISO --------------------------------SFV--PSAPTEV-----I-------PNP MACMU8_150_PE22 NOISO ----------------------------PPGTRPV--PTFAEKV-----S---------- MAIZE_2_PE7014 NOISO --------------LRLAGLVPPSCTPTPPPPPASSWPAGPTLAVQLGDILNRSDDELRL MICMUGS_3858_PE24 NOISO ----------------------------PSGTGAD--PTAPNEV-----S---------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN ----------------------------PKSHLSV--PFAPPEV-----I-------PSS MONDO3_446_PE29 ENSMODG00000011014 ----------------------------PKSHLSV--PFAPPEV-----I-------PSS MOUSE15_PE705 ENSMUSG00000033762 ----------------------------PPGSKTE--SPCPDEA-----D---------- MOUSE15_PE706 ISOFORMIN ----------------------------PPGSKTE--SPCPDEA-----D---------- MYOLUGS_4426_PE2 NOISO ----------------------------LPAAGAS--PASPEEV-----S---------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ----------------------------XXXXXXX--XXXXXXX-----X---------- ORNANCONTIG341_PE6 ENSOANG00000003526 ----------------------------PNVL---------GEV-----Q-------SAK ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO ----------------------------PSDPEAI--LLSPNEA-----S---------- PANTR8_151_PE26 NOISO ----------------------------PPGTGPV--PSFAEKV-----S---------- PEDHC_890_PE62 NOISO SLSSNCA----------------------------------EEN-----N---DNKSDGI PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO ----------------------------SPGTAAA--LISPEEV-----G---------- PIG4_1_PE7 NOISO ----------------------------SPGTAAA--LISPEEV-----G---------- PONPY8_159_PE8 NOISO ----------------------------PPGTGPV--PSFAEKA-----S---------- POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO ----------------------------PPDAGVT--TVSP-KV-----S---------- RAT7_PE1328 ENSRNOG00000032446 ----------------------------PPGPRTE--SPCPEQA-----N---------- RAT7_PE1329 ISOFORMIN ----------------------------PPGPRTE--SPCPEQA-----N---------- SORARGS_5380_PE3 NOISO ----------------------------PPHTEA--------VV-----S---------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ----------------------------PPSPRTA--PTSPEEV-----S---------- TARSYGS_5559_PE1 NOISO ----------------------------PSGTEAD--PTSP-EV-----S---------- TETNG21RD_PE128 ENSTNIG00000017539 VLLNLPS-FYRNSVASLVSLDSATVQPAVPEDQFK--PLEPVKE-----SFDDSSHAN-- TETNG21RD_PE129 ISOFORMIN VLLNLPS-FYRNSVASLVSLDSATVQPAVPEDQFK--PLEPVKE-----SFDDSSHAN-- TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ----------------------------FPKPPGT--PISPPE------LLQDTPSEP-- MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO AAD---------------SNVLINSTI---QISNTSSYIPQPLSILQK------------ AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO ------------------------------------EVLLQP------------------ ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_2_PE1395 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_3_PE1398 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_4_PE1398 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_5_PE1397 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_6_PE1398 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_7_PE1397 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_8_PE1398 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- ANOGA_9_PE1398 HAPLOTYPE ESN---------------ATKVEE-K-----LPA-------------------------- APIME_119_PE11 NOISO ---------------------------------------------FHSI----------- APIME_119_PE12 NOISO EET---------------KSIFGE-S-----MKI---TYMESTSTVHSI----------- ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN ------------------------------------EVLPQP------------------ BOVIN14_1_PE18 ENSBTAG00000010276 ------------------------------------EVLPQP------------------ BOVIN14_1_PE19 ISOFORMIN ------------------------------------EVLPQP------------------ BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO ------------------------------------DTPPQP------------------ CANFA13_42_PE41 NOISO ------------------------------------EELLQL------------------ CAVPO95_4_PE36 NOISO ------------------------------------DSLTKP------------------ CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO EET---------------S------P-----IQA-------------------------- CULQU_602_PE10 NOISO EET---------------S------P-----IQA-------------------------- DANRE19_4_PE9 NOISO -----------------F-----------PSI-----TPSKPCST-----VVG------- DASNOGS_5448_PE2 NOISO ------------------------------------EVPLPP------------------ DIPORGS_5063_PE4 NOISO ------------------------------------DVFLQP------------------ DROME3L_9_PE65 NOISO KEK---------------QQAIAN---------N-------------------------- ECHTEGS_6465_PE2 NOISO -----------------------------XXXXXXXXXXXXX------------------ ERIEUGS_6628_PE4 NOISO ------------------------------------XXXXXX------------------ FELCAGS_5236_PE10 NOISO ------------------------------------EVPLQP------------------ FUGRU37_1_PE108 ENSTRUG00000012749 CDN----------SKSSFKKTVGTDNVNVSGLNPSPAGASVPSSSLASPANVG------- FUGRU37_1_PE109 ISOFORMIN CDN----------SKSSFKKTVGTDNVNVSGLNPSPAGASVPSSSLASPANVG------- FUGRU37_1_PE110 ISOFORMIN ------------------------------------------------------------ GASACGROUPIII_7_PE38 NOISO CGTTN--NIS---IESSTSKVIGSQNPNVPCPAPSPARPSALLSSVSSSPGAG------- GORGO8_151_PE6 NOISO ------------------------------------DEPPQL------------------ HORSE9_86_PE8 NOISO ------------------------------------EVPPQA------------------ HS8_PE3578 ISOFORMIN ------------------------------------DEPPQL------------------ HS8_PE3579 ENSG00000160957 ------------------------------------DEPPQL------------------ LOXAF185_PE18 NOISO ------------------------------------QVPPQC------------------ MACEUGS_7560_PE2 NOISO CEDPS------------------------------FPGL--------------------- MACMU8_150_PE22 NOISO ------------------------------------DEPPQP------------------ MAIZE_2_PE7014 NOISO LYLLHRLSLSAETRGGAFLPILGNHEV----MNVSGDFRFATPQGFHDRAVCGGVLACAG MICMUGS_3858_PE24 NOISO ------------------------------------DVPPKP------------------ MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN CEGDV------------------------VMLKPSIPTWSCG------------------ MONDO3_446_PE29 ENSMODG00000011014 CEGDV------------------------VMLKPSIPTWSCG------------------ MOUSE15_PE705 ENSMUSG00000033762 ------------------------------------DALPRV------------------ MOUSE15_PE706 ISOFORMIN ------------------------------------DALPRV------------------ MYOLUGS_4426_PE2 NOISO ------------------------------------EVLPQL------------------ NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ------------------------------------XXXXXX------------------ ORNANCONTIG341_PE6 ENSOANG00000003526 CTPPS-----------------------------PYSGRPGG------------------ ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO ------------------------------------DVQLKP------------------ PANTR8_151_PE26 NOISO ------------------------------------DEPPQL------------------ PEDHC_890_PE62 NOISO CDSRE-----------SGLESISTSSLSSSSMSIS----PLL--TSSVLPSSG------- PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO ------------------------------------KVPSQL------------------ PIG4_1_PE7 NOISO ------------------------------------KVPSQL------------------ PONPY8_159_PE8 NOISO ------------------------------------DEPPHP------------------ POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO ------------------------------------DVPSQP------------------ RAT7_PE1328 ENSRNOG00000032446 ------------------------------------DALPQV------------------ RAT7_PE1329 ISOFORMIN ------------------------------------DALPQV------------------ SORARGS_5380_PE3 NOISO ------------------------------------SGPLQS------------------ SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ------------------------------------GGHPQP------------------ TARSYGS_5559_PE1 NOISO ------------------------------------DVSPLS------------------ TETNG21RD_PE128 ENSTNIG00000017539 CYT----------GKDSSKNNISADHLNVSGLNSPPARASVPLS-----DNVG------- TETNG21RD_PE129 ISOFORMIN CYT----------GKDSSKNNISADHLNVSGLNSPPARASVPLS-----DNVG------- TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO SDT----------SS----------H---ISLKEPPPKPAWNPSA------LG------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO ------------LNNSFEASP----------------KMMTVNRKLDEGWLERCNENNSK AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO ------------------HGPQL-RPGRL---QQLQASLSLRLSSLDPDWLQRCHNGAPD ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_2_PE1395 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_3_PE1398 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_4_PE1398 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_5_PE1397 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_6_PE1398 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_7_PE1397 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_8_PE1398 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- ANOGA_9_PE1398 HAPLOTYPE --------------------------PPL---V---PTQSEPINQLDERWINRLSGGTG- APIME_119_PE11 NOISO --------------------------GTV---QQ-LIEGHTVNRNLNPGWLSRCAKQNNL APIME_119_PE12 NOISO --------------------------GTV---QQ-LIEGHTVNRNLNPGWLSRCAKQNNL ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN ------------------PRPQL-RPGRL---QQLRASLSLRLGSLDPDWLQRCHNRTPD BOVIN14_1_PE18 ENSBTAG00000010276 ------------------PRPQL-RPGRL---QQLRASLSLRLGSLDPDWLQRCHNRTPD BOVIN14_1_PE19 ISOFORMIN ------------------PRPQL-RPGRL---QQLRASLSLRLGSLDPDWLQRCHNRTPD BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO ------------------SGLRP-RPGRL---QHLRASLSVRLGSLDPGWLQRCHSGVPD CANFA13_42_PE41 NOISO ------------------PGPQP-RPGRL---QQLQASLSLRLSSLDPGWLERCHSAASD CAVPO95_4_PE36 NOISO ------------------SEPPP-KPGQF---QQLQASLSLRLCSLDPGWLQRCQNGALD CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO --------------------------PTL---N---QQPKEVVNQLDQGWLNRQTGQSG- CULQU_602_PE10 NOISO --------------------------PTL---N---QQPKEVVNQLDQGWLNRQTGQSG- DANRE19_4_PE9 NOISO ---------SAQKSV---ERVQ-----------FLRQSITRRFSSVDSGWLARCQVFDEV DASNOGS_5448_PE2 NOISO ------------------PGPQP-RPGRL---QQLQLSLSLRLSSLDPGWLQRCHGGAPD DIPORGS_5063_PE4 NOISO ------------------SGPQP-MPGRL---QRLQASRRLGLGSLDPHWLQRCQNMASD DROME3L_9_PE65 NOISO --------------------------PML---AS-EHSKESIKTLVDDGWLRRNTKENTL ECHTEGS_6465_PE2 NOISO ------------------XXPQP-RPAWL---QQLQSPLSRRLASLDPGWLQRCQDGSPE ERIEUGS_6628_PE4 NOISO ------------------XXXXX-XXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXX FELCAGS_5236_PE10 NOISO ------------------AGPQL-RPGCL---QQLQASLSLRLGSLDPGWLERCHNGAPD FUGRU37_1_PE108 ENSTRUG00000012749 ---------IAKRDSAFKEDQQVFR-----------------LSLIDTKWLERCQVFGEM FUGRU37_1_PE109 ISOFORMIN ---------IAKRDSAFKEDQQVFRGVRG---IAARPSPVGRLSLIDTKWLERCQVFGEM FUGRU37_1_PE110 ISOFORMIN -------------------PSPVGR-----------------LSLIDTKWLERCQVFGEM GASACGROUPIII_7_PE38 NOISO ---------SSRRADE-TSGCRRGIGVSG---LGGKSSPASRLSFVDRKWLERCQVFGEM GORGO8_151_PE6 NOISO ------------------PEPQP-RPGRL---QHLQASLSQRLGSLDPGWLQRCHSEVPD HORSE9_86_PE8 NOISO ------------------LKPQL-RPGRL---QQLRASLSLRLNSLDPGWLQRCHNEAPD HS8_PE3578 ISOFORMIN ------------------PEPQP-RPGRL---QHLQASLSQRLGSLDPGWLQRCHSEVPD HS8_PE3579 ENSG00000160957 ------------------PEPQP-RPGRL---QHLQASLSQRLGSLDPGWLQRCHSEVPD LOXAF185_PE18 NOISO ------------------PGPQP-RPGRL---KHLQSSLSLRLGSLDPGWLQRCHDGAPD MACEUGS_7560_PE2 NOISO ------------------------WTGLF---QHLQHTLGQRLSSLDPGWLQRCQDGTR- MACMU8_150_PE22 NOISO ------------------PGPQP-RPGQL---QHLQACLSQQLASLDLDWLQRCHSEIPD MAIZE_2_PE7014 NOISO FAAWAAEAGVAGAAGCWRTGVAG--AGAVYTASLIVSRDCLKLNSTLGLWTCFCPIRSKP MICMUGS_3858_PE24 NOISO ------------------PEPQP-RPGRL---QQLRASLSLRLGSLDPGWLHRCHNGASD MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN ------------------PKFIP-QLGKL---KQLQHTLGQRLSSLDPGWLQRCQDEAKE MONDO3_446_PE29 ENSMODG00000011014 ------------------PKFIP-QLGKL---KQLQHTLGQRLSSLDPGWLQRCQDEAKE MOUSE15_PE705 ENSMUSG00000033762 ------------------PEPRP-RLGQL---QQLRSSLSRRLTSLDPGWLERCHNRVSD MOUSE15_PE706 ISOFORMIN ------------------PEPRP-RLGQL---QQLRSSLSRRLTSLDPGWLERCHNRVSD MYOLUGS_4426_PE2 NOISO ------------------PRPQL-RPGRL---QQLQESLSLRLGSLDPGWLQRCHET-EG NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ------------------XXXXX-XXXXX---XXXXXXXXXXXXXXXPDWLQ-CHHGSPG ORNANCONTIG341_PE6 ENSOANG00000003526 ------------------VTPNP-RPGRL---RQVRRSLNRRLSSLDPGWLERCQNGTGE ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO ------------------SGPQP-RPGRL---QQLQASLNLRLVSLDPGWLQRCHTGASD PANTR8_151_PE26 NOISO ------------------PEPQP-RPGRL---QHLQASLSQRLGSLDPGWLQRCHSEVPD PEDHC_890_PE62 NOISO ---------SLIERCSFIDGKTTPNVQKF---NFLQDMTSRQLSTFQEDWVERCTNFDDN PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO ------------------PRTQL-RSGRL---QELRASLSLRLSSLDPGWLQRCHSGTPD PIG4_1_PE7 NOISO ------------------PRTQL-RSGRL---QELRASLSLRLSSLDPGWLQRCHSGTPD PONPY8_159_PE8 NOISO ------------------PEPQP-RPGRL---QHLQASLSQRLGSLDPGWLQRCHSEVPD POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO ------------------PRPQL-RPGRL---QQLQASLSLRLGSLNPDWLQRCHSGAPD RAT7_PE1328 ENSRNOG00000032446 ------------------PVPQP-RQGQL---QKLQSSLSLRLSSLDPGWLERCQNRVSD RAT7_PE1329 ISOFORMIN ------------------PVPQP-RQGQL---QKLQSSLSLRLSSLDPGWLERCQNRVSD SORARGS_5380_PE3 NOISO ------------------SRPQP-KPVRP---QQLRASLSLRLGSLDPDWLQRCDREPDD SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ------------------SEPKR-SPGRL---QQLRASLRLRLGSLDPGWLQRCHSGPLD TARSYGS_5559_PE1 NOISO ------------------PGPQP-RPGRL---QKLQTSLSLRLGSLDPDWLQRCHEGVSD TETNG21RD_PE128 ENSTNIG00000017539 ---------VAKEDVAVREGPQVFRGVRG---TGARASSISRLSLIDKKWLERCQVFGEM TETNG21RD_PE129 ISOFORMIN ---------VAKEDVAVREGPQVFRGVRG---TGARASSISRLSLIDKKWLERCQVFGEM TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ---------QPIK-----K---------Q---HQLQAMVGQRMASLNQEWLQRCELRNGA MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO ITNSNI-------------------------------TQPDLKKEIES-----DTDVVYE AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO FLGAS------------------------------KACQPNLG----------------- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_2_PE1395 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_3_PE1398 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_4_PE1398 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_5_PE1397 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_6_PE1398 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_7_PE1397 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_8_PE1398 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA ANOGA_9_PE1398 HAPLOTYPE DSNVTTTGARPSSERPTPTNFGLRNVNVASL----------ASA---------TSFGMSA APIME_119_PE11 NOISO EYPAFDSQR--LSGT---SDSGIESTESS-IYSPKENVILSLPP---------KSFEISD APIME_119_PE12 NOISO EYPAFDSQR--LSGT---SDSGIESTESS-IYSPKENVILSLPP---------KSFEISD ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN FLEVP------------------------------RTCQPGLG----------------- BOVIN14_1_PE18 ENSBTAG00000010276 FLEVP------------------------------RTCQPGLG----------------- BOVIN14_1_PE19 ISOFORMIN FLEVP------------------------------RTCQPGLG----------------- BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO ILGAP------------------------------KPCRSGLG----------------- CANFA13_42_PE41 NOISO CLRAS------------------------------AACQPSLG----------------- CAVPO95_4_PE36 NOISO FLPAS------------------------------DPCK--------------------- CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO QTP---------SATPQPVRYGLRNITIPPVVESPAIVTPVDTS---------TSFGMSA CULQU_602_PE10 NOISO QTP---------SATPQPVRYGLRNITIPPIVEPPAIATPVDTS---------TSFGMSA DANRE19_4_PE9 NOISO EEPQKP---------------VAGNSEL-----AK-DEKSFLQPAVGSKSGSPGTHGERV DASNOGS_5448_PE2 NOISO SLGIP------------------------------KASGPHLG----------------- DIPORGS_5063_PE4 NOISO FPEAP------------------------------SACWPGLG----------------- DROME3L_9_PE65 NOISO DEEVPFAEANNNSGTSKKTNFGLANLDLSKLKPTVKEE-KVLQA---------KPDQMAI ECHTEGS_6465_PE2 NOISO LLEAT------------------------------DACGPGLS----------------- ERIEUGS_6628_PE4 NOISO XXXXX------------------------------XXXXXXXX----------------- FELCAGS_5236_PE10 NOISO FLGAS------------------------------KACQPNLG----------------- FUGRU37_1_PE108 ENSTRUG00000012749 ETEVKP---------------GAGNQEK-----PP-GMREEE---VDRIAGNKEKDGLRD FUGRU37_1_PE109 ISOFORMIN ETEVKP---------------GAGNQEK-----PP-GMREEE---VDRIAGNKEKDGLRD FUGRU37_1_PE110 ISOFORMIN ETEVKP---------------GAGNQEK-----PP-GMREEE------------------ GASACGROUPIII_7_PE38 NOISO GAEVKP---------------GAGNQEV-----EQENGGEGEG--------GRETEGKIQ GORGO8_151_PE6 NOISO FLGAP------------------------------KTCRPDLG----------------- HORSE9_86_PE8 NOISO FQGAP------------------------------EACHPGLD----------------- HS8_PE3578 ISOFORMIN FLGAP------------------------------KACRPDLG----------------- HS8_PE3579 ENSG00000160957 FLGAP------------------------------KACRPDLG----------------- LOXAF185_PE18 NOISO LLGVP------------------------------GACRPSLG----------------- MACEUGS_7560_PE2 NOISO ------------------------------------------------------------ MACMU8_150_PE22 NOISO FLGAP------------------------------KACRPGLG----------------- MAIZE_2_PE7014 NOISO NPL--------------PSYIDI------------------------------------- MICMUGS_3858_PE24 NOISO FLEAP------------------------------KACRPGLD----------------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN KPERLEHSSSLS-----S-------LSEVQEPCPEKKCTESQH----------------- MONDO3_446_PE29 ENSMODG00000011014 KPERLEHSSSLS-----S-------LS--------------------------------- MOUSE15_PE705 ENSMUSG00000033762 LLEVP------------------------------GACGLDLS----------------- MOUSE15_PE706 ISOFORMIN LLEVP------------------------------GACGLDLS----------------- MYOLUGS_4426_PE2 NOISO FLGTS------------------------------EACQPVPG----------------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO VGV-----------------------------------SPGLE----------------- ORNANCONTIG341_PE6 ENSOANG00000003526 RSPGREAISAPP-----PP--PPGPQTRPEDPSPPGRCRPRAP----------------- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO FLGAP------------------------------KACRSGLG----------------- PANTR8_151_PE26 NOISO FLGAP------------------------------KACRPDLG----------------- PEDHC_890_PE62 NOISO IKPQRNS-------------------------------DSGFDSIASE-----EVKL--N PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO FPGVP------------------------------RARGPGGD----------------- PIG4_1_PE7 NOISO FPGVP------------------------------RARGPGGD----------------- PONPY8_159_PE8 NOISO FLGAP------------------------------KACRPDLG----------------- POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO FLGTP------------------------------EVCQPVLG----------------- RAT7_PE1328 ENSRNOG00000032446 PLEVP------------------------------GACGLDLS----------------- RAT7_PE1329 ISOFORMIN PLEVP------------------------------GACGLDLS----------------- SORARGS_5380_PE3 NOISO P-----------------------------------------G----------------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO FLKPP------------------------------SACSPGLG----------------- TARSYGS_5559_PE1 NOISO FLGAP------------------------------EACRPGLG----------------- TETNG21RD_PE128 ENSTNIG00000017539 ENEAKP---------------GAGNQEN-----VL-NMGKEE---AERKLRNEEEDGGRE TETNG21RD_PE129 ISOFORMIN ENEAKP---------------GAGNQEN-----VL-NMGKEE---AERKLRNEEEDGGRE TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO EPMEVT---------------AAEQRNV-----NREQCDSTLEPLAEGAIESTDLHITSN MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO --------------------------SDNETQD-----IPLYSSQ--------------- AEDAE_4224_PE7 NOISO ------------------------------------------------------------ AILMEGL192891_1_1_PE17 NOISO ---------------------------VQESQ-------PLTPG------------V--- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_2_PE1395 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_3_PE1398 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_4_PE1398 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_5_PE1397 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_6_PE1398 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_7_PE1397 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_8_PE1398 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV ANOGA_9_PE1398 HAPLOTYPE L-----SMTDKAGGTAVKR----KIFTS--INR-----SP-VER-VEAKQPKPSIETNNV APIME_119_PE11 NOISO EEDFVCNSDSEEGHKNKRIRNIKKEFSNQESYS-----SKRMC--LENTSTLNKINVQTI APIME_119_PE12 NOISO EEDFVCNSDSEEGHKNKRIRNIKKEFSNQESYS-----SKRMC--LENTSTLNKINVQTI ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN ---------------------------AEDSQ-------LLTPV------------V--- BOVIN14_1_PE18 ENSBTAG00000010276 ---------------------------AEDSQ-------LLTPV------------V--- BOVIN14_1_PE19 ISOFORMIN ---------------------------AEDSQ-------LLTPV------------V--- BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO ---------------------------LEESQ-------LLTAG------------E--- CANFA13_42_PE41 NOISO ---------------------------VEESQ-------PLTSG------------V--- CAVPO95_4_PE36 NOISO ---------------------------AEESQ-------PVTAG------------E--- CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO L-----SMSSFVAEAPTSE----TVTVQNTAYA-----AP-VQS-DS----DGVVENSED CULQU_602_PE10 NOISO L-----SMSSFVAEAPARE----TVTVQNTAYA-----AP-VQS-DS----DGVVENSED DANRE19_4_PE9 NOISO ----S------------------HKNSPNEGQTFS----NTLLGRKKSSLPEEEAQIDLV DASNOGS_5448_PE2 NOISO ---------------------------GQEAGVAA------------------------- DIPORGS_5063_PE4 NOISO ---------------------------AEESH-------SVASG------------D--- DROME3L_9_PE65 NOISO IQELQTDMNSSMNQKPD------------HLNH-----TPPASS-QKSVAPKNKPPPSEQ ECHTEGS_6465_PE2 NOISO ---------------------------SEEPGKEP--QLPQTSG------------V--- ERIEUGS_6628_PE4 NOISO ---------------------------XXXXX-------XXXXX------------X--- FELCAGS_5236_PE10 NOISO ---------------------------VEQSQ-------SLTSC------------V--- FUGRU37_1_PE108 ENSTRUG00000012749 ----A------------------GHS--EGGEAL------------KGHAPDEDVHKRR- FUGRU37_1_PE109 ISOFORMIN ----A------------------GHS--EGGEAL------------KGHAPAYI------ FUGRU37_1_PE110 ISOFORMIN ------------------------------------------------------------ GASACGROUPIII_7_PE38 NOISO TDDKV------------------------EGQE-----------------KDAEVIR--- GORGO8_151_PE6 NOISO ---------------------------SEESQ-------LLIPG------------E--- HORSE9_86_PE8 NOISO ---------------------------TDLSQ-------PLT-L------------S--- HS8_PE3578 ISOFORMIN ---------------------------SEESQ-------LLIPG------------E--- HS8_PE3579 ENSG00000160957 ---------------------------SEESQ-------LLIPG------------E--- LOXAF185_PE18 NOISO ---------------------------AEELCSPGEGSQPPTSG------------V--- MACEUGS_7560_PE2 NOISO ------------------------------------------------------------ MACMU8_150_PE22 NOISO ---------------------------SEESQ-------LLIPG------------E--- MAIZE_2_PE7014 NOISO --------GSWAGLVNPRRRKKYMLPSA-NWQEM----KKLSSGKKSGK-GDGLG-R--- MICMUGS_3858_PE24 NOISO ---------------------------SEESQ-------TLTLG------------K--- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN ---------------------------SAKTDLRSVFNDGDGFSDASLP-------E--- MONDO3_446_PE29 ENSMODG00000011014 --------------------------------------------------------E--- MOUSE15_PE705 ENSMUSG00000033762 ---------------------------AEESQ-------PQMSG------------K--- MOUSE15_PE706 ISOFORMIN ---------------------------AEESQ-------PQMSG------------K--- MYOLUGS_4426_PE2 NOISO ---------------------------TGEPP-------PLTSG------------V--- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ----------------------------PECQ-------LLTIG------------Q--- ORNANCONTIG341_PE6 ENSOANG00000003526 ---------------------------AAKKRQRESG----------------------- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO ---------------------------SEESQ-------TLNFG------------A--- PANTR8_151_PE26 NOISO ---------------------------SEESQ-------LLIPG------------E--- PEDHC_890_PE62 NOISO ----------------------------NEKS--------LF-S-------DNNDDD--- PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO ---------------------------AEESQ-------LTS-G------------V--- PIG4_1_PE7 NOISO ---------------------------AEESQ-------LTS-G------------V--- PONPY8_159_PE8 NOISO ---------------------------SEESQ-------LLTPG------------E--- POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO ---------------------------TEKPQ-------PQTSG------------V--- RAT7_PE1328 ENSRNOG00000032446 ---------------------------AKESQ-------PQMSG------------K--- RAT7_PE1329 ISOFORMIN ---------------------------AKESQ-------PQMSG------------K--- SORARGS_5380_PE3 NOISO ---------------------------TVTSQ-------P-------------------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ---------------------------RKESQ-------HLTSG------------E--- TARSYGS_5559_PE1 NOISO ---------------------------LE-TQ-------PLTSG------------E--- TETNG21RD_PE128 ENSTNIG00000017539 ----T------------------ENF--ER-DGL------------KSQSPDKNVP---- TETNG21RD_PE129 ISOFORMIN ----T------------------ENF--ER-DGL------------KSQSPDKNVP---- TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO NDEFAHSVTSPTHS--------VLAFTPGPSQHAASPSLPLTFGR-LDKSPEKPKQK-AV MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO ------------------------------------------------------------ AEDAE_4224_PE7 NOISO -----------------------------------------------------------M AILMEGL192891_1_1_PE17 NOISO ---------------PSVLGPSTGPE---------------------------------- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_2_PE1395 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_3_PE1398 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_4_PE1398 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_5_PE1397 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_6_PE1398 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_7_PE1397 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_8_PE1398 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA ANOGA_9_PE1398 HAPLOTYPE VSV-ESKDVENQDPCGVAE--EAEQGA--TPKGAPKK---RVQKRVSKAKQVAKKMVEKA APIME_119_PE11 NOISO HCIEDVNTIFNEEKCNVVLSKNNSTNN--N---I------NI------------------ APIME_119_PE12 NOISO HCIEDVNTIFNEEKCNVVLSKNNSTNN--N---I------NI------------------ ARALY_1_PE2902 NOISO ------------------------------------------------------------ ARATH_1_PE3672 NOISO ------------------------------------------------------------ BOVIN14_1_PE17 ISOFORMIN ---------------ESVLSPSAGPEV----------------------------PL--- BOVIN14_1_PE18 ENSBTAG00000010276 ---------------ESVLSPSAGPEV----------------------------PL--- BOVIN14_1_PE19 ISOFORMIN ---------------ESVLSPSAGPEV----------------------------PL--- BRADI_5_PE1289 NOISO ------------------------------------------------------------ CALJA16_53_PE9 NOISO ---------------SAVLGPGAGSQ---------------------------------- CANFA13_42_PE41 NOISO ---------------PSVLGASPGPE---------------------------------- CAVPO95_4_PE36 NOISO ---------------LPVLVSSTCSKA----------------------------SS--- CIOIN3Q_5_PE89 NOISO ------------------------------------------------------------ CULQU_306_PE9 NOISO ESV-G------------------------------------------------------- CULQU_602_PE10 NOISO ESV-GGGSLNTSAVRHVVKKRKVEAEE--EPK---AK---RVRKAV---APKAKKVVKKA DANRE19_4_PE9 NOISO ---------TSSVRNNVVLNAISGSPG----------------------------TH--- DASNOGS_5448_PE2 NOISO ----------------LGQDPSVVSEA----------------------------SS--- DIPORGS_5063_PE4 NOISO ---------------LAILGPDTGPP---------------------------------- DROME3L_9_PE65 NOISO --------ETDSDSDSVVA--ESEEEQ--EPQEYRQLS--KRRKIV----STASGKVEVA ECHTEGS_6465_PE2 NOISO ---------------LATLG------N----------------------------TG--- ERIEUGS_6628_PE4 NOISO ---------------XXXXXXXXXXXX----------------------------XX--- FELCAGS_5236_PE10 NOISO ---------------PSVPGPSTSS----------------------------------- FUGRU37_1_PE108 ENSTRUG00000012749 -------------------------PK-----------------------------Q--- FUGRU37_1_PE109 ISOFORMIN ------------------------------------------------------------ FUGRU37_1_PE110 ISOFORMIN ------------------------------------------------------------ GASACGROUPIII_7_PE38 NOISO -------------------RAVKDLES----------------------------DK-AF GORGO8_151_PE6 NOISO ---------------SAVLGPGAGSQ---------------------------------- HORSE9_86_PE8 NOISO ---------------VPSVGPSTGPEA----------------------------PL--- HS8_PE3578 ISOFORMIN ---------------SAVLGPGAGSQ---------------------------------- HS8_PE3579 ENSG00000160957 ---------------SAVLGPGAGSQ---------------------------------- LOXAF185_PE18 NOISO ---------------LAAPRTCSGSE---------------------------------- MACEUGS_7560_PE2 NOISO ------------------------------------------------------------ MACMU8_150_PE22 NOISO ---------------SAVLGPGAGSP---------------------------------- MAIZE_2_PE7014 NOISO ----PGESLDSQARQIAVRSPLPWREAYQSSPQIPRYSPLRLRSRLRRRAPPSPPAPHRA MICMUGS_3858_PE24 NOISO ---------------LAVLGPGTGSEA----------------------------LS--- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN ---------------TLTTKPVFGSLP--------------------------------- MONDO3_446_PE29 ENSMODG00000011014 ---------------TLTTKPVFGSLP--------------------------------- MOUSE15_PE705 ENSMUSG00000033762 ---------------VNIADPDIQSEV----------------------------SV--- MOUSE15_PE706 ISOFORMIN ---------------VNIADPDIQSEV----------------------------SV--- MYOLUGS_4426_PE2 NOISO ---------------PSDPGPSTGPEA----------------------------PF--- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ---------------QSSVDPIAGCEA--------------------------------- ORNANCONTIG341_PE6 ENSOANG00000003526 ------------------------------------------------------------ ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------------------------------------------------------ ORYSJ_7_PE4100 NOISO ------------------------------------------------------------ OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO ---------------VATLGPGTGSEV----------------------------LS--- PANTR8_151_PE26 NOISO ---------------SAVLGPGAGSQ---------------------------------- PEDHC_890_PE62 NOISO ------------------------------------------------------------ PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO ---------------PCVLSPSIGPKV----------------------------PL--- PIG4_1_PE7 NOISO ---------------PCVLSPSIGPKV----------------------------PL--- PONPY8_159_PE8 NOISO ---------------SAVLGPGGGSQ---------------------------------- POPTR_2_PE618 NOISO ------------------------------------------------------------ PTEVAGS_3119_PE13 NOISO ---------------LSVLGPSTGPGE----------------------------PL--- RAT7_PE1328 ENSRNOG00000032446 ---------------VNVISPDILSEV----------------------------SS--- RAT7_PE1329 ISOFORMIN ---------------VNVISPDILSEV----------------------------SS--- SORARGS_5380_PE3 NOISO ----------------SISAPHTGPDA----------------------------Y---- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ---------------FLVFGPNTCSEE----------------------------FS--- TARSYGS_5559_PE1 NOISO ---------------SAGLGLVTGSEI----------------------------LS--- TETNG21RD_PE128 ENSTNIG00000017539 --------------------------Q-----------------------------H--- TETNG21RD_PE129 ISOFORMIN --------------------------Q-----------------------------H--- TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ---------ETPGRNSIVRSRVTDSVS----------------------------SRNKR MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO ------------------------------------------------------RIKAQE AEDAE_4224_PE7 NOISO ISSWVPVRRTTRGCKPIQYNQPNESE---------------------------------- AILMEGL192891_1_1_PE17 NOISO ------------------------------------------------------------ ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_2_PE1395 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_3_PE1398 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_4_PE1398 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_5_PE1397 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_6_PE1398 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_7_PE1397 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_8_PE1398 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- ANOGA_9_PE1398 HAPLOTYPE KTVVVPRARSSRT-------------NA-------------------------------- APIME_119_PE11 NOISO -----------QTNLLNNIDKCNEKIKH-------------------------------- APIME_119_PE12 NOISO -----------QTNLLNNIDKCNEKIKH-------------------------------- ARALY_1_PE2902 NOISO ----------------MD-------------------SDSDSDGS-----H------VSA ARATH_1_PE3672 NOISO ----------------MD-------------------FDSDSDGS-----H------VSA BOVIN14_1_PE17 ISOFORMIN Q------------------------------------------DP--------------- BOVIN14_1_PE18 ENSBTAG00000010276 Q------------------------------------------DP--------------- BOVIN14_1_PE19 ISOFORMIN Q------------------------------------------DP--------------- BRADI_5_PE1289 NOISO MNLWSH---------AAA-------------------ADSDSDGS-----L---LSDVSA CALJA16_53_PE9 NOISO -------------------------------------------GP--------------- CANFA13_42_PE41 NOISO ------------------------------------------------------------ CAVPO95_4_PE36 NOISO Q------------------------------------------DP--------------- CIOIN3Q_5_PE89 NOISO -----------MKK--MEE-------------EISNTCEMPSKDDKTNLIKDTERAGLGE CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO QPVKVPARKIPTRGRKANYKQCVEGEGE-------------------------------- DANRE19_4_PE9 NOISO ----------------------------------------------------GERVSLKS DASNOGS_5448_PE2 NOISO G------------------------------------------DP--------------- DIPORGS_5063_PE4 NOISO -------------------------------------------GP--------------- DROME3L_9_PE65 NOISO APVEIPNKVEPET------------ETF-------------------------------- ECHTEGS_6465_PE2 NOISO P------------------------------------------DP--------------- ERIEUGS_6628_PE4 NOISO X------------------------------------------XX--------------- FELCAGS_5236_PE10 NOISO ------------------------------------------------------------ FUGRU37_1_PE108 ENSTRUG00000012749 ----------------------------------------------------S-----QQ FUGRU37_1_PE109 ISOFORMIN ------------------------------------------------------------ FUGRU37_1_PE110 ISOFORMIN ----------------------------------------------------S-----QQ GASACGROUPIII_7_PE38 NOISO KGT------------TSEETVCAA------------------------------------ GORGO8_151_PE6 NOISO -------------------------------------------GP--------------- HORSE9_86_PE8 NOISO P------------------------------------------AP--------------- HS8_PE3578 ISOFORMIN -------------------------------------------GP--------------- HS8_PE3579 ENSG00000160957 -------------------------------------------GP--------------- LOXAF185_PE18 NOISO ------------------------------------------------------------ MACEUGS_7560_PE2 NOISO ------------------------------------------------------------ MACMU8_150_PE22 NOISO -------------------------------------------DP--------------- MAIZE_2_PE7014 NOISO TPMYSQ---------LVD-------------------GDSDSEGS-----L---ISDISA MICMUGS_3858_PE24 NOISO Q------------------------------------------AP--------------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN E------------------------------------------KE--------------- MONDO3_446_PE29 ENSMODG00000011014 E------------------------------------------KE--------------- MOUSE15_PE705 ENSMUSG00000033762 Q------------------------------------------SP--------------- MOUSE15_PE706 ISOFORMIN Q------------------------------------------SP--------------- MYOLUGS_4426_PE2 NOISO L------------------------------------------GS--------------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ------------------------------------------------------------ ORNANCONTIG341_PE6 ENSOANG00000003526 ------------------------------------------------------------ ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO --MYSP---------PHA-------------------ADSDSEGS-----L---LSDVSA ORYSJ_7_PE4100 NOISO --MYSP---------PHA-------------------ADSDSEGS-----L---LSDVSA OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO Q------------------------------------------GS--------------- PANTR8_151_PE26 NOISO -------------------------------------------GP--------------- PEDHC_890_PE62 NOISO ----------------DDDVICGS------------DNEL-------------------- PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO L------------------------------------------SP--------------- PIG4_1_PE7 NOISO L------------------------------------------SP--------------- PONPY8_159_PE8 NOISO -------------------------------------------GP--------------- POPTR_2_PE618 NOISO ----------------ME-------------------SDSDSDGS-----H------VSS PTEVAGS_3119_PE13 NOISO Q------------------------------------------GP--------------- RAT7_PE1328 ENSRNOG00000032446 Q------------------------------------------SP--------------- RAT7_PE1329 ISOFORMIN Q------------------------------------------SP--------------- SORARGS_5380_PE3 NOISO T------------------------------------------DS--------------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO Q------------------------------------------GP--------------- TARSYGS_5559_PE1 NOISO Q------------------------------------------GP--------------- TETNG21RD_PE128 ENSTNIG00000017539 ----------------------------------------------------S-----HQ TETNG21RD_PE129 ISOFORMIN ----------------------------------------------------S-----HQ TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO EGVWDPDQQPLERKFPVRQRICVESKASLAEAGMGAHNQLDSKGPMSNGSKQLQDIDVGQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO ------FSDSQNS-----MNQ-----ETIVDNNETS---RSSKKRYNSDEEF-------- AEDAE_4224_PE7 NOISO ----------------EEGGDFDPDDDDKDPD----FK-ETAGDHSLHDEEPTEEVTE-P AILMEGL192891_1_1_PE17 NOISO ------TRALQIAGVSAGSPR---------------PGNSQDKKWRWSREPE-------- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_2_PE1395 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_3_PE1398 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_4_PE1398 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_5_PE1397 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_6_PE1398 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_7_PE1397 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_8_PE1398 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S ANOGA_9_PE1398 HAPLOTYPE ---------------RKVEHEFSADDEDKDPD----YK-EQLERESRGLLPADGDDLE-S APIME_119_PE11 NOISO ---------------VPEIETNTYDEENAEKSSKERLVNHKIQRKF-KHISSDDSDFE-N APIME_119_PE12 NOISO ---------------VPEIETNTYDEENAEKSSKERLVNHKIQRKF-KHISSDDSDFE-N ARALY_1_PE2902 NOISO TPPRDSFPPSPPPLLQPP-------PKYVPPVSRKITSSSSRSKPKAPTQPPPNPSQEAP ARATH_1_PE3672 NOISO TPPRDSFPSSPP-QLQSP-------AKHVPPVSRKMTSSSSRSKPKAPTHPPPNPSQEAP BOVIN14_1_PE17 ISOFORMIN -----EAPALPAAAVSAGKCQ---------------PVDRQGKKRRQSGELE-------- BOVIN14_1_PE18 ENSBTAG00000010276 -----EAPALPAAAVSAGKCQ---------------PVDRQGKKRRQSGELE-------- BOVIN14_1_PE19 ISOFORMIN -----EAPALPAAAVSAGKCQ---------------PVDRQGKKRRQSGELE-------- BRADI_5_PE1289 NOISO SPPRRCSPPRPPPPPP---PP--P-KRRPRPDPT--------SKPKRKPKPTPLPS---- CALJA16_53_PE9 NOISO -----EASALQEVSIGAGNPQ---------------PSGSRGEKRRRNEVPW-------- CANFA13_42_PE41 NOISO ------GRALQRAAVGAGSPE---------------AGNSQGKKRRRTKETG-------- CAVPO95_4_PE36 NOISO -----YGPVPQAAQTNAGSFQ---------------LCNHRSKKQKWTKEKG-------- CIOIN3Q_5_PE89 NOISO IP------------------VFVT------------------------------------ CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO ---------------EDKDPYEDFDDSDKDPD----FN-DGKKEE--HEE-SAEDVSM-E DANRE19_4_PE9 NOISO SPKLRVDD-ENLSEEPEFTPNTKQ-RKTKARKDQDSGAKTKG--RKRQREADNGDDMD-E DASNOGS_5448_PE2 NOISO -----EAPALPATSVPGGSSQ---------------PSHRQSKKRRWSGGPR-------- DIPORGS_5063_PE4 NOISO -----EASSPQAARVALGSPP---------------LSNS-KKKWKWSKENW-------- DROME3L_9_PE65 NOISO ---------------AQENPDFSADEDQ-DAT----YVPENKKKDKAKRKQAAGKQKT-T ECHTEGS_6465_PE2 NOISO -----EGPTLQEAGGNKGNPR---------------PSKTPTPGWDPQGA---------- ERIEUGS_6628_PE4 NOISO -----XXXXXXXXXXXXXXXX---------------XXXXXXXXXXXXXXXX-------- FELCAGS_5236_PE10 NOISO ------AQALQTAGVSAGSPQ---------------PGDSPGKRWXXXXXXX-------- FUGRU37_1_PE108 ENSTRUG00000012749 LMQENVTDGQQESPETSLIPLANTEDKNKLKKN-GDYTKKKG--KKRQR---EGETMG-G FUGRU37_1_PE109 ISOFORMIN ------------------------------------------------------------ FUGRU37_1_PE110 ISOFORMIN LMQENVTDGQQESPETSLIPLANTEDKNKLKKN-GDYTKKKG--KKRQR---EGETMG-G GASACGROUPIII_7_PE38 NOISO ------TSSHQSNMEKELTPPLTAEDDNKTSN--------------RSK----------- GORGO8_151_PE6 NOISO -----EASALQEVSIRAGSPQ---------------PSSSGGKKRRRNEEPW-------- HORSE9_86_PE8 NOISO -----EAPTLQAVRVSAGSPQ---------------PSNTRGKKRRRSEEPG-------- HS8_PE3578 ISOFORMIN -----EASAFQEVSIRVGSPQ---------------PSSSGGEKRRWNEEPW-------- HS8_PE3579 ENSG00000160957 -----EASAFQEVSIRVGSPQ---------------PSSSGGEKRRWNEEPW-------- LOXAF185_PE18 NOISO ------APVLEGAS----DNK---------------RSIQPNKKQRQSGDAG-------- MACEUGS_7560_PE2 NOISO ------------------------------------------------------------ MACMU8_150_PE22 NOISO -----EASALQEVSIRAGSPQ---------------PSSSRGKKQRRNKELW-------- MAIZE_2_PE7014 NOISO SPPRGRSPSPPPPPP----PP--P-EHRPNPKHT---ATVKPKPPKSKAKPKLAAS---- MICMUGS_3858_PE24 NOISO -----KPPALQAAQPGTGSPQ---------------PSNSQGKKRRWSEEPW-------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN -----DAPSMSEGVWE----S---------------GSSGD------P------------ MONDO3_446_PE29 ENSMODG00000011014 -----DAPSMSEVRTL----Q---------------RNLTQKRQRDESQDRT--LKH--- MOUSE15_PE705 ENSMUSG00000033762 -----EAIAQQPAQVLSQSPK---------------SINSKGRKRKWNEK---------- MOUSE15_PE706 ISOFORMIN -----EAIAQQPAQVLSQSPK---------------SINSKGRKRKWNEK---------- MYOLUGS_4426_PE2 NOISO -----EAPAMKVPGVSAGNPL---------------LGGSQGKKRRKSGELK-------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO -------SGALAAHTHADDL-------------------QPGQKRSRNEGPG-------- ORNANCONTIG341_PE6 ENSOANG00000003526 --------------EE----E---------------EAAAPKRQRKRPDDPV--S----- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO SPPRRRSPPRPAPPPPPPPPP--P-KHRTRPAA--------PTKPKLKPTPPAASA---- ORYSJ_7_PE4100 NOISO SPPRRRSPPRPAPPPPPPPPP--P-KHRTRPAA--------PTKPKLKPTPPAASA---- OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO -----EVSGLQNARAR--SPQ---------------PS-KKSNKPRWSEEPW-------- PANTR8_151_PE26 NOISO -----EASALQEVSIRAGSPQ---------------PSSSGGEKRRWNEEPW-------- PEDHC_890_PE62 NOISO ----------------------NKEDNNII---------SLSQKRKSQV----------- PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO -----EAPAPQAAGVSAGSPQ---------------PGNSQGKKRRLSWELQ-------- PIG4_1_PE7 NOISO -----EAPAPQAAGVSAGSPQ---------------PGNSQGKKRRLSWELQ-------- PONPY8_159_PE8 NOISO -----EISAFQEVSIGAGRPQ---------------PSSSRGEKRRRNEEPW-------- POPTR_2_PE618 NOISO TPPRNPMPPPPSPRRPTLLSS--H-KSKIRLKSSSFSSKSQRKLPFEPAEPPPQPSLDDT PTEVAGS_3119_PE13 NOISO -----EAPALPAARVSAGSPP---------------LGSSQSKKQRQEGELE-------- RAT7_PE1328 ENSRNOG00000032446 -----QALAQQPAQVLSQIPK---------------SSNSKDRKRKRNEK---------- RAT7_PE1329 ISOFORMIN -----QALAQQPAQVLSQIPK---------------SSNSKDRKRKRNEK---------- SORARGS_5380_PE3 NOISO -----EAPALQTVTSQ--------------------SCTSEDKKRRQSE-P--------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO -----ETPAPQAAQNDMGSPQ---------------PSNPQGKKPKWSET-G-------- TARSYGS_5559_PE1 NOISO -----EDPILQSTTVGSGSLQ---------------PSNCQGKKQRWRQGSQ-------- TETNG21RD_PE128 ENSTNIG00000017539 KPREKVNNRQKEAIEPP-PMLSNTEEESK-----------------QRK---NSNSRQ-N TETNG21RD_PE129 ISOFORMIN KPREKVNNRQKEAIEPP-PMLSNTEEESK-----------------QRK---NSNSRQ-N TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO VMKNRTRPRQQSPQEVDGMPQ------ETIAGGEASAILSKGKRKKRQREIS---AEQ-D MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO ---------------------------EE-----C------------SIQS--------- AEDAE_4224_PE7 NOISO IEA-EV-SPQAKPAR------KSVARKSR---AKQPSSTGERKRRSGSAKKSPSAPRIGG AILMEGL192891_1_1_PE17 NOISO -----GS-----P-----------AQAQQ-----D------------GGQ---------- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_2_PE1395 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_3_PE1398 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_4_PE1398 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_5_PE1397 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_6_PE1398 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_7_PE1397 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_8_PE1398 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR ANOGA_9_PE1398 HAPLOTYPE DQEEEP-KPKSAPAK------RLSP---------------------GSSKP---APQRGR APIME_119_PE11 NOISO DEKEKKNKKNISKTK------RITTRKNKST--KES------------STKEIKTRTRKR APIME_119_PE12 NOISO DEKEKKNKKNISKTK------RITTRKNKST--KES------------STKEIKTRTRKR ARALY_1_PE2902 NOISO TS-FSPPPPPPSPLF--TD---LPFRICE------------SQPARFSSSIS-------- ARATH_1_PE3672 NOISO VPSPYPPPPPPSPLF--TN---LPFRICQ------------SQPARFSSSVS-------- BOVIN14_1_PE17 ISOFORMIN -----GR-----L-----------AQTQQ-----G------------TDQ---------- BOVIN14_1_PE18 ENSBTAG00000010276 -----GR-----L-----------AQTQQ-----G------------TDQ---------- BOVIN14_1_PE19 ISOFORMIN -----GR-----L-----------AQTQQ-----G------------TDQ---------- BRADI_5_PE1289 NOISO -STSAPASAPPLPAAALSDPHGLTARIAPASAL--------TANASTVSFSS-------- CALJA16_53_PE9 NOISO -----GS-----P-----------TQVQQ-----Q------------SSQ---------- CANFA13_42_PE41 NOISO -----GG-----P-----------AQAQQ-----D------------SGQ---------- CAVPO95_4_PE36 NOISO -----SS-----P-----------MQAQQ-----D------------YSQ---------- CIOIN3Q_5_PE89 NOISO ---ENPSVSMASTE----------NEASK-----DIST--------LSVPSNPV------ CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO VPEEKQ-KPKKE---------VKAPRKSRAKAVTTSPTTGRKRRSGSAAKKSPAAPRIGG DANRE19_4_PE9 NOISO SEEKEGGVKKRRK-----------TKKGE-----TA-----------GEDQ-PK------ DASNOGS_5448_PE2 NOISO -----GV-----A-----------GQAQQ-----D------------SSQ---------- DIPORGS_5063_PE4 NOISO -----GS-----P-----------AQGHW-----V------------SSH---------- DROME3L_9_PE65 NOISO KPKAEP-KPKTEKK-------------AK-----------------VKAEKKPKAEKKPR ECHTEGS_6465_PE2 NOISO ------------P-----------PQTQW-----D------------QDH---------- ERIEUGS_6628_PE4 NOISO -----XX-----X-----------XXXXX-----X------------XXX---------- FELCAGS_5236_PE10 NOISO -----XX-----X-----------XXXXX-----X------------XXX---------- FUGRU37_1_PE108 ENSTRUG00000012749 EVSEEGGAKKRRRN----------AKKES-----SD-----------GNPS-PD------ FUGRU37_1_PE109 ISOFORMIN ------------------------------------------------------------ FUGRU37_1_PE110 ISOFORMIN EVSEEGGAKKRRRN----------AKKES-----SD-----------GNPS-PD------ GASACGROUPIII_7_PE38 NOISO ---------DTSRN----------VKKTE-----ES-----------SN----I------ GORGO8_151_PE6 NOISO -----GS-----P-----------AQVQQ-----E------------SSQ---------- HORSE9_86_PE8 NOISO -----GS-----P-----------AQAQQ-----D------------SSQ---------- HS8_PE3578 ISOFORMIN -----ES-----P-----------AQVQQ-----E------------SSQ---------- HS8_PE3579 ENSG00000160957 -----ES-----P-----------AQVQQ-----E------------SSQ---------- LOXAF185_PE18 NOISO -----GA-----P-----------SQAQW-----D------------SSY---------- MACEUGS_7560_PE2 NOISO ------------------------------------------------------------ MACMU8_150_PE22 NOISO -----GS-----P-----------AQVQQ-----Q------------SSQ---------- MAIZE_2_PE7014 NOISO -ACTAAVSPPPLPSAALSDPHGLVSRIAAAPAL--------VTATSTVSSSS-------- MICMUGS_3858_PE24 NOISO -----AS-----P-----------TQVQR-----D------------SGQ---------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN -----------------------------------Q-----------G------------ MONDO3_446_PE29 ENSMODG00000011014 --QKIGTKKKKLRS----------ESAPE-----SN-----------GEH---------- MOUSE15_PE705 ENSMUSG00000033762 -----GE-----D-----------FAQDQ-----P------------SSG---------- MOUSE15_PE706 ISOFORMIN -----GE-----D-----------FAQDQ-----P------------SSG---------- MYOLUGS_4426_PE2 NOISO -----GT-----AA----------AQARQ-----H------------SSQ---------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO -----GS-----L-----------ACVQQ-----E------------GGQ---------- ORNANCONTIG341_PE6 ENSOANG00000003526 ------------RD----------RQASD-----SS-----------GRH---------- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO -PAPAPPPPPTLRAAALSDPHGLAARIAAGSAL--------TAASGTASSSS-------- ORYSJ_7_PE4100 NOISO -PAPAPPPPPTLRAAALSDPHGLAARIAAGSAL--------TAASGTASSSS-------- OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO -----AS-----P-----------AQVEQ-----D------------SGQ---------- PANTR8_151_PE26 NOISO -----ES-----P-----------AQVQQ-----E------------SSQ---------- PEDHC_890_PE62 NOISO --------------------------LQD-----EN-----------SSQE--K------ PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO -----GS-----P-----------AQPQQ-----D------------GNQ---------- PIG4_1_PE7 NOISO -----GS-----P-----------AQPQQ-----D------------GNQ---------- PONPY8_159_PE8 NOISO -----GS-----P-----------AQVQQ-----E------------SSH---------- POPTR_2_PE618 NOISO SLN--------LPSL--ST---LPFQIRCSSNLHRP-NLIETLPAGYFSKST-------- PTEVAGS_3119_PE13 NOISO -----ES-----P-----------AQAQQ-----N------------SGH---------- RAT7_PE1328 ENSRNOG00000032446 -----GE-----D-----------FAQAQ-----P------------SSQ---------- RAT7_PE1329 ISOFORMIN -----GE-----D-----------FAQAQ-----P------------SSQ---------- SORARGS_5380_PE3 NOISO ------------------------YRAQE-----D------------QGA---------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO -----GS-----P-----------VQSQQ-----D------------ISQ---------- TARSYGS_5559_PE1 NOISO -----GS-----S-----------AQAQW-----H------------SSK---------- TETNG21RD_PE128 ENSTNIG00000017539 KMSEESGVKKRRRK----------AKKES-----CE-----------DNLS-PD------ TETNG21RD_PE129 ISOFORMIN KMSEESGVKKRRRK----------AKKES-----CE-----------DNLS-PD------ TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO AVEESPKVSKKRRK----------TKMSP-----DN-----------GEKSSPV------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO ---------------------------------KILKTHDHDS----------------- AEDAE_4224_PE7 NOISO NTGKGKKRV-ARKPA--VKVPVSDEEPD---KEDGFNDYVLEF----G--IESLNNAPRV AILMEGL192891_1_1_PE17 NOISO ------------------AGSLPEEAGAAEHTGDCPGEPLW----V-QP-P--------- ANOCA1050_PE2 NOISO ------------------------------------------------------------ ANOGA_1_PE1398 AGAP005917 KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_2_PE1395 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_3_PE1398 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_4_PE1398 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_5_PE1397 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_6_PE1398 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_7_PE1397 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_8_PE1398 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL ANOGA_9_PE1398 HAPLOTYPE KAK---KIT-KRKMDVD---GEEEEAAP---EAEQPQEYVPEF----G--LARLRSIPRL APIME_119_PE11 NOISO SSR-KKKDI-QDEDDLFETDNVNHEITK---SRNHEDKKSEIY----G--IETLEAVPRF APIME_119_PE12 NOISO SSR-KKKDI-QDEDDLFETDNVNHEITK---SRNHEDKKSEIY----G--IETLEAVPRF ARALY_1_PE2902 NOISO ----SFSRL--RSR--ASFTPNEKLKSD---GVDFVPEPP-------------------- ARATH_1_PE3672 NOISO ----SFSRL--CSR--ASFTSVEKLKSD---GVDFVPEPPLVEVIA-------------- BOVIN14_1_PE17 ISOFORMIN ------------------AGPLPEGAGAAGPAEDCPDQPVK----A-QP-P--------- BOVIN14_1_PE18 ENSBTAG00000010276 ------------------AGPLPEGAGAAGPAEDCPDQPVK----A-QP-P--------- BOVIN14_1_PE19 ISOFORMIN ------------------AGPLPEGAGAAGPAEDCPDQPVK----A-QP-P--------- BRADI_5_PE1289 NOISO ----FRRLV-ESRN--LSIDPVATCTAP---APDPPPASDPVPAEIPSAAPCPSTAAAAA CALJA16_53_PE9 NOISO ------------------AGPPSETAEAIALEEDSPGEPVQ----EQPPQPCSSRSTPRY CANFA13_42_PE41 NOISO ------------------AGPPPEEAGAVGPAEDCPGEPLR----V-QP-A--------- CAVPO95_4_PE36 NOISO ------------------ARLLSEGAGATALKDPTRGA-----VQVQTPQ---------- CIOIN3Q_5_PE89 NOISO QAEDKI-------SDDFPANLNKSEESPPVRIKGQPEKIESEN----------------- CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO NTGKGKKRP-VRQVKAKGKAPPPEEEEP---KEEEFNEYVLEF----G--IDSLNNAPRI DANRE19_4_PE9 NOISO KRGKKKGKV--EEDDDDGSSENKKPQKRAMPQENLLGEVDEEE----------------- DASNOGS_5448_PE2 NOISO ------------------AGPLPGEAGPVEPKGGPVKEPPSQL---------SKTPPPRY DIPORGS_5063_PE4 NOISO ------------------TAPEGAVAMASALEKDSSEEQIE----VKPPQP--------- DROME3L_9_PE65 NOISO N---SKKAI-AVEP---APDPEEDERQP---LNPEDLKYVLAL----E--AGDITSVPRI ECHTEGS_6465_PE2 NOISO ------------------VRPWLKDAGATELNEDALED--------QSPRPRISSSTPRY ERIEUGS_6628_PE4 NOISO ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX-------XX FELCAGS_5236_PE10 NOISO ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXX FUGRU37_1_PE108 ENSTRUG00000012749 QAGGKKRRV--KKKDGETEEEKDTKLPKEDPKENLLGELEEEY----------------- FUGRU37_1_PE109 ISOFORMIN ------------------------------------------------------------ FUGRU37_1_PE110 ISOFORMIN QAGGKKRRV--KKKDGETEEEKDTKLPKE------------------------------- GASACGROUPIII_7_PE38 NOISO NPRPKKGWLVSL----YSSLHSVNAVRGEVPHENLLGEIEEEY----------------- GORGO8_151_PE6 NOISO ------------------AGPPSEGAGAVALEEDLPGEPVQ----AQPPQPCSSPSNPRY HORSE9_86_PE8 NOISO ------------------PELPPEGAGATAHAEGCLGEPVQ----A-QL-P--------- HS8_PE3578 ISOFORMIN ------------------AGPPSEGAGAVAVEEDPPGEPVQ----AQPPQPCSSPSNPRY HS8_PE3579 ENSG00000160957 ------------------AGPPSEGAGAVAVEEDPPGEPVQ----AQPPQPCSSPSNPRY LOXAF185_PE18 NOISO ------------------VGPQPKDAGAAEPKEDPLGEQSPRP-------P----SGPTT MACEUGS_7560_PE2 NOISO ------------------------------------------------------------ MACMU8_150_PE22 NOISO ------------------AGPPSEGAGAVALEEDPPGEPVQ----AQPPQPCSSLSTPRY MAIZE_2_PE7014 NOISO ----FRRLV-QSRN--PSFDPAAAFSAP---TPAPTLAPTEIATA--ATAQ---CPAPDA MICMUGS_3858_PE24 NOISO ------------------AGPPSEGARAIALEEDPAGESVQ----AQQPQPCSTPSALRY MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN -------------------RPSGRNGRGE-----------------------DG----QD MONDO3_446_PE29 ENSMODG00000011014 ------------------TRESGRVAALEIPKEDLLGEMVV----ERMAKTVTGAKAPRY MOUSE15_PE705 ENSMUSG00000033762 ------------------AGPLSEGARATVHGQDPPGEPTQVN----VPQP--------- MOUSE15_PE706 ISOFORMIN ------------------AGPLSEGARATVHGQDPPGEPTQVN----VPQP--------- MYOLUGS_4426_PE2 NOISO ------------------EGSPPEGARAVLHAEDCPGEPTQ----AQPHG----PSAPRC NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO ------------------EAE-----------KDTVGGPAG----G-------------- ORNANCONTIG341_PE6 ENSOANG00000003526 ------------------GKKPVQM-AAPEAEEDLLGEIAG----ANTPRPLASVSTRRY ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ----FRRLV-QSRN--PSFDPATAFTAP---ASSA---PSEVPSAAPRPPP---TAATDA ORYSJ_7_PE4100 NOISO ----FRRLV-QSRN--PSFDPATAFTAP---ASSA---PSEVPSAAPRPPP---TAATDA OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO ------------------AEPLCDRGGAVALEEDPAGKPAP----GQPPLPCISPLAPRY PANTR8_151_PE26 NOISO ------------------AGPPSEGAGAVAVEEDPPGEPVQ----AQPPQPCSSPSNPRY PEDHC_890_PE62 NOISO SHNDKMGN--------FSFHHLLNSATTHVTKKFKMDASSETT-----------LKSSSY PHPAT1_665_PE34 NOISO ------------------------------------------------------------ PIG4_1_PE21 NOISO ------------------GGPPPEGAAAAGHTEDCLEEPVR----A-QP-L--------- PIG4_1_PE7 NOISO ------------------GGPPPEGAAAAGHTEDCLEEPVR----A-QP-L--------- PONPY8_159_PE8 NOISO ------------------AGSPSEGAGAVALEEDPPGEPVQ----AQPPQPCSSPSTPRY POPTR_2_PE618 NOISO ----FFSKI-QRPS--LNFEPSESFTCP---PVSADRAPPENK----------------- PTEVAGS_3119_PE13 NOISO ------------------AGSLPGGAGAAALSGHCPGAPVQ----AQPRS----PTARRY RAT7_PE1328 ENSRNOG00000032446 ------------------AGPLSEGAGATAHGQGPPGEPTQVT----VPQH--------- RAT7_PE1329 ISOFORMIN ------------------AGPLSEGAGATAHGQGPPGEPTQVT----VPQH--------- SORARGS_5380_PE3 NOISO ------------------VGFPTHSAGPALVDEASPGVPTH----PF------CTPVPRC SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO ------------------TGPLSEGTGAVALEEDLPGQPVQ----AQPSQPRSSSSSPS- TARSYGS_5559_PE1 NOISO ------------------ARSP---TGSVTLEEDPPEEPVQ----AEPPQPCSLPSVSRY TETNG21RD_PE128 ENSTNIG00000017539 QEGGKKKRV--NL------------CPAKVPKENLLGEIEEEL----------------- TETNG21RD_PE129 ISOFORMIN QEGGKKKRV--NL------------CPAKVPKENLLGEIEEEL----------------- TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO QNRRKRGARRNDSSDDPSMESPASEQGAKPVSEDLFGELEEET----------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO --------------------VQ-----L-------STKDRRKKVVLESKISSGKASENFV AEDAE_4224_PE7 NOISO DIGELIKSTQVVESFIQGVPVKKAKVKAK--KSDDEEVLTPKEAALRSKAAAGKLNENFV AILMEGL192891_1_1_PE17 NOISO S---------------A---PR-----ASRRDRVGQALGML--SSYVLSRSALRSGGNYV ANOCA1050_PE2 NOISO --------------------------------------------------------GNFV ANOGA_1_PE1398 AGAP005917 DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_2_PE1395 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_3_PE1398 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_4_PE1398 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_5_PE1397 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_6_PE1398 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_7_PE1397 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_8_PE1398 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV ANOGA_9_PE1398 HAPLOTYPE DINELVRDTKLADSFILGVAGSAAEGPSSSGKTRTTVAGSTKETALRKKMAAGKLNENFV APIME_119_PE11 NOISO AIYKNCQGD-LIEQFAKSVSLKTNDLSSK-S-IIKPRGQLTDKEKLEKKIAEGKTNENFV APIME_119_PE12 NOISO AIYKNCQGD-LIEQFAKSVSLKTNDLSSK-S-IIKPRGQLTDKEKLEKKIAEGKTNENFV ARALY_1_PE2902 NOISO -----------------QPP-----------NLI-TDTITSPPVKPMVFRSSGNGEGNFV ARATH_1_PE3672 NOISO P----------PKSVRRKPP-----------NLI-TDTITSPPVKPMVFRSNGNGEGNFV BOVIN14_1_PE17 ISOFORMIN G---------------R---TP-----AS--------------------RSAIQDRGNYV BOVIN14_1_PE18 ENSBTAG00000010276 G---------------R---TP-----ASS---VGRAVGTA--DLCVSSRSAIQDRGNYV BOVIN14_1_PE19 ISOFORMIN G---------------R---TP-----AS--------------------RSAIQDRGNYV BRADI_5_PE1289 NOISO P---------PQARPKRVHP-----------NSV-SEVP--MAAAEQPKRPRGGGEGNFV CALJA16_53_PE9 NOISO H---------------R---LS-----PSSQARAEKAEGIA--HLHIFPRLAGYDRGNYI CANFA13_42_PE41 NOISO S---------------G---PT-----ATR---YHSALGTT--RSYILSSSAVRDQGNYV CAVPO95_4_PE36 NOISO L---------------Y---SG-----TSSPAEAGKAESTP--HLHTSPRTAIRDKGNYV CIOIN3Q_5_PE89 NOISO --------------------ME-----TSQQNEK-GAKSTSKSGGSSGGGGGGLASTNFR CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO DLGELKKSTQAVESFIQGIPTGKSAVLTK---VKGEEVVTSKEAAMRKKVAAGKLNENFV DANRE19_4_PE9 NOISO ---------------------------------ARAAAYAM--KNTVRVRPTKNTDGNFV DASNOGS_5448_PE2 NOISO P---------------SPDPPE-----PPSRAGTGVAECPA--HPRVPSRPAPQDRGNYV DIPORGS_5063_PE4 NOISO --------------------HS-----SSSGVRAEKAEVMA--HMHTPPRPAGLDRGNYV DROME3L_9_PE65 NOISO NVQDLEEADATAQRYIRTFAAGPNPGLSEGSNIRVDEKRAAARKKLEERIAAGKLNENFV ECHTEGS_6465_PE2 NOISO H---------------TPTPST-----PVSGL-LQVESDVE--TLLVSPRSTFQERGNYV ERIEUGS_6628_PE4 NOISO X---------------X---XX-----XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXX FELCAGS_5236_PE10 NOISO X---------------X---XX-----XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXX FUGRU37_1_PE108 ENSTRUG00000012749 ---------------------------------K-TRRTRL--SLPVRARNPNGPEGNFV FUGRU37_1_PE109 ISOFORMIN -----------------------------------------------LHRNPNGPEGNFV FUGRU37_1_PE110 ISOFORMIN ------------------------------------------------VKNPNGPEGNFV GASACGROUPIII_7_PE38 NOISO ---------------------------------A-ARRTYR--TPPVKASGKKGLEGNFV GORGO8_151_PE6 NOISO Y---------------G---LS-----PSSQARAGKAEGTA--HLHIFPRLARHDRGNYV HORSE9_86_PE8 NOISO S---------------I---PA-----APSPARW-EASGMA--HLCVLSRPAIQDRGNYV HS8_PE3578 ISOFORMIN H---------------G---LS-----PSSQARAGKAEGTA--PLHIFPRLARHDRGNYV HS8_PE3579 ENSG00000160957 H---------------G---LS-----PSSQARAGKAEGTA--PLHIFPRLARHDRGNYV LOXAF185_PE18 NOISO P---------------R---WV-----TSELSWVRRAVGTA--HPDISPRSTLQEGGNYV MACEUGS_7560_PE2 NOISO ------------------------------------------------------DSGNFV MACMU8_150_PE22 NOISO H---------------R---FS-----TSSQARAGKAEGTA--HLHI-SRLARHDRGNYV MAIZE_2_PE7014 NOISO P---------PQTRPKRVHP-----------NSV-SEVVPPAAEAEQPKRPRGGAEGNFV MICMUGS_3858_PE24 NOISO H---------------S---FS-----PLSQARAGKAEGMS--HLHISPRPAVPDRGNYI MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN C------------------HWG-----Q--SPQRWQSSSVT--ELWVFFRTFSKANGNFV MONDO3_446_PE29 ENSMODG00000011014 C---------------SQVKLG-----R---QTSNHSDHFT--ELWVFFRTFSKANGNFV MOUSE15_PE705 ENSMUSG00000033762 --------------------CN-----SSNQARTEKAKGTT--HLHASPRPASLDRGNYI MOUSE15_PE706 ISOFORMIN --------------------CN-----SSNQARTEKAKGTT--HLHASPRPASLDRGNYI MYOLUGS_4426_PE2 NOISO --------------------FS-----PLSW-AKGDAMGKA--HLYVPSRPAARDRGNYV NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO --------------------GS-----LSCGACVGQTVGTA--PLCSSPRTGVQERGNYV ORNANCONTIG341_PE6 ENSOANG00000003526 F---------------LV-----------------EGGGTF--EMGGSVGAAPKASGNFV ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO P---------PQTRPKRVHP-----------NSV-SEVAAASAAAEQPKRARGGSEGNFV ORYSJ_7_PE4100 NOISO P---------PQTRPKRVHP-----------NSV-SEVAAASAAAEQPKRARGGSEGNFV OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO R---------------G---FS-----PLSV--RAGAEGMS--HLHISFRSAVKSKGNYV PANTR8_151_PE26 NOISO H---------------G---LS-----PSSQARAGKAEGTA--PLHIFPRLARHDRGNYI PEDHC_890_PE62 NOISO N---------------N------------------EENAKM--KILERKIQCGTLNDNYV PHPAT1_665_PE34 NOISO --------------------------------------------ASGPTKLRTGERDNFV PIG4_1_PE21 NOISO S---------------N---PT-----TSSQGEW-AS-RTA--HLCISSRPAIQDRGNYV PIG4_1_PE7 NOISO S---------------N---PT-----TSSQGEW-AS-RTA--HLCISSRPAIQDRGNYV PONPY8_159_PE8 NOISO H---------------R---LS-----PSSQARAGKAEGTA--HLHIFPRLARHDRGNYV POPTR_2_PE618 NOISO -----------PNNFIKKHP-----------NLI-GANAPLPPA---KL--RKCSEGNFV PTEVAGS_3119_PE13 NOISO H---------------N---FG-----TLSA-RVERALGTA--HLCVPCRPAVCDRGNYV RAT7_PE1328 ENSRNOG00000032446 --------------------RC-----SSNQARTENAKSAA--HLPMSPRPASLDRGNYV RAT7_PE1329 ISOFORMIN --------------------RC-----SSNQARTENAKSAA--HLPMSPRPASLDRGNYV SORARGS_5380_PE3 NOISO H---------------S---PS-----PLRRAWVNSTLGKA--HLCIPSRPTRHNRGNYV SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO --------------------------------RRKKPKG----MAYVVPRPAIQDRSNYV TARSYGS_5559_PE1 NOISO H---------------G---FG-----PSSQAKAGKAED-------VSPRLTSHHKGNYV TETNG21RD_PE128 ENSTNIG00000017539 ---------------------------------K-TRRTHL--THPIRARSTKAAEGNFV TETNG21RD_PE129 ISOFORMIN ---------------------------------K-TRRTHL--THPIRARSTKAAEGNFV TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------------------------ XENTR1850_PE1 NOISO ---------------------------------AQ--RISV--KTAKATRMPQIKSENFV MATCH CONSENSUS ?????????????????????????????????????????????????????????N?V

ACYPI_11004_PE3 NOISO KLDMKRKIYSRGKRSVK---TTTYKKKQWKNRKQELGGDFSATNR------------TTL AEDAE_4224_PE7 NOISO RVDLRKKVFVRGKKTVN---YSKYKKSLWKKKK-AAALSGPDMDM------GG--CDGGV AILMEGL192891_1_1_PE17 NOISO RLNMKRKRSVRGPALRGRLLRKQMWKQKWQKKGERFGGGQPRAA--------------AK ANOCA1050_PE2 NOISO CLNLKKRSHVKGFALRGKHLRKQVWKQKWQKKGELFGGGGG---------------GRSS ANOGA_1_PE1398 AGAP005917 RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_2_PE1395 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_3_PE1398 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_4_PE1398 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_5_PE1397 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_6_PE1398 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_7_PE1397 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_8_PE1398 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT ANOGA_9_PE1398 HAPLOTYPE RIDIRKKVFVKGKKTIN---YSRYKKSQWKAKK-AAALTGPEMDM------RG--CDGGT APIME_119_PE11 NOISO RINLKKKVFVRGKKHFN---FSKYKKNQWKQRKKDLGSSENSLAI------ADFVEKNSV APIME_119_PE12 NOISO RINLKKKVFVRGKKHFN---FSKYKKNQWKQRKKDLGSSENSLAI------ADFVEKNSV ARALY_1_PE2902 NOISO KLNLNGKRGKKFP--SK-YKGVSKSRSNYAFRGKR-Y--KKKEAD------G------DG ARATH_1_PE3672 NOISO KLNLNGKRGKKFP--SK-YKGVSKSRSSYSFRGKR-Y--KKKEAD------G------DG BOVIN14_1_PE17 ISOFORMIN RLNMKQRRYVRGRALRGRLLRKQAWKQKWQKKGECFGGGQPRAP--------------AQ BOVIN14_1_PE18 ENSBTAG00000010276 RLNMKQRRYVRGRALRGRLLRKQAWKQKWQKKGECFGGGQPRAP--------------AQ BOVIN14_1_PE19 ISOFORMIN RLNMKQRRYVRGRALRGRLLRKQAWKQKWQKKGECFGGGQPRAP--------------AQ BRADI_5_PE1289 NOISO RLNINGYGRKRTFK-SQ-ARRSTKYRS------WRRQQPGGAKAR------G------GV CALJA16_53_PE9 NOISO RLNMKQKRYVRGRVLRGRLLRKQAWKQKWQKKGECFGSGDATFT--------------IK CANFA13_42_PE41 NOISO RLNLKQKRYVRGPAQRGRLLRKQMWKQKWRKKGEHFGGSQARAT--------------AD CAVPO95_4_PE36 NOISO RLNMKQRRYVRGGALRGRLLRKQVWKQKWQKKREHFGGGRPRAI--------------VE CIOIN3Q_5_PE89 NOISO RLNMKQKTFSRKG-GQGRFLRKQVFREKLSKKGFSFRSGWKGRSGGSSLGGGGGYRDRSD CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO RVDLRKKVFVKGKKTIN---FSKYKKSLWKQKK-AAALSGPEMDM------GG--CDGGV DANRE19_4_PE9 NOISO KINLKKKSHVKGFALRGAALRKQMYMQKFQLKGERFGGGFG---R--GRGRFGG-FNRQG DASNOGS_5448_PE2 NOISO RLNLKHKRYARGPALQGRRLRRQVWKQKWQKKGECFGGGQSRAT--------------GE DIPORGS_5063_PE4 NOISO RLNMKQKRYVQGRTSRGRLLQKQVQKQKWQKKGERFRGGRLRAT--------------VE DROME3L_9_PE65 NOISO TINIQKKKFVRGKKSVN---FSKYKKQQWRHKKRVAALSGPDMDM------GG--CDGGV ECHTEGS_6465_PE2 NOISO KLNLKQKRYARGPALRGAHLRKQVRKQSGRRRRVCFRSSYSGTP--------------AQ ERIEUGS_6628_PE4 NOISO XXXMKRKCYVRGLALPGRFFSKLMWKQKWQKKEEYLGRRQPRST--------------DG FELCAGS_5236_PE10 NOISO XXXXKQKRYVRGPALRGRLLRKQMWKQKWQKKEERFVGGRPXXX--------------XX FUGRU37_1_PE108 ENSTRUG00000012749 KINLKKKSHVKGYALRGVGLRKQLYMQKFQLKGERFGGGAGYFGRGS----------RQG FUGRU37_1_PE109 ISOFORMIN KINLKKKSHVKGYALRGVGLRKQLYMQKFQLKGERFGGGAGYFGRG-------------- FUGRU37_1_PE110 ISOFORMIN KINLKKKSHVKGYALRGVGLRKQLYMQKFQLKGERFGGGGGF----S----------RQG GASACGROUPIII_7_PE38 NOISO KINLKKKSHVKGYAVRGAGLRKQMYMQKFQLKGEPFGGGGGFFGRGRRGGFRGG-ISRQG GORGO8_151_PE6 NOISO RLNMKQKHYVRGRALRGRLLRKQAWKQKWRKKGKCFGGGGATVT--------------TK HORSE9_86_PE8 NOISO RLNLKQKRYARGPALRGRLLRKQVWKQKWQKKGERFGGGKLRAT--------------VK HS8_PE3578 ISOFORMIN RLNMKQKHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGATVT--------------TK HS8_PE3579 ENSG00000160957 RLNMKQKHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGATVT--------------TK LOXAF185_PE18 NOISO RLNLRQKRYVRGPALRGSQLRKQVWKQKWQKKQECFGGSHPKST--------------FK MACEUGS_7560_PE2 NOISO RLNLKKKCYVKGFGLRGNLLRKQIWKKKWQMKGEQFGGGWPRDR--------------GK MACMU8_150_PE22 NOISO RLNMKQKRYVQGRALRGRLLRKQAWKQKWRKKGECFGGGGATVT--------------IK MAIZE_2_PE7014 NOISO RLNINGYGRRRTFRNAQ-ARRPTKYRS------WRRQRHGGAKPQ------G------RG MICMUGS_3858_PE24 NOISO RLNMKQKRYTRGRALRGRLLRKQAWKQKWQKKGECFGGDGPRAT--------------V- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN RLNLKKKCYAKGFVLRGKHLRKQIWKKKWQMKGEQFGGGWSRGR--------------GK MONDO3_446_PE29 ENSMODG00000011014 RLNLKKKCYAKGFVLRGKHLRKQIWKKKWQMKGEQFGGGWSRGR--------------GK MOUSE15_PE705 ENSMUSG00000033762 RLNMKNKRFVRVGANRGRLLRKQVWKQKWKKKQAAFGGSGPRAT--------------DK MOUSE15_PE706 ISOFORMIN RLNMKNKRFVRVGANRGRLLRKQVWKQKWKKKQAAFGGSGPRAT--------------DK MYOLUGS_4426_PE2 NOISO RLNLKQKRYVWGPALRGRLLRKQAWKQKWKKKAEHLGGGQSNAP--------------VK NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO RLNMKQRRYVRWA--FGRALLRQARKQKWQKKATGLTGGRPKAT--------------SR ORNANCONTIG341_PE6 ENSOANG00000003526 RLNMKKKCYVKASALRGNHLRKQVWKQKWQKKGQQFGGGGSHGS-------------HEN ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO RLNINGYGRRRTFKNSQ-AKRSTKCRS------WRRQRAAGATPR------S------QG ORYSJ_7_PE4100 NOISO RLNINGYGRRRTFKNSQ-AKRSTKCRS------WRRQRAAGATPR------S------QG OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO RLNMKHRRCTRGQALRGRLLRRQARMQKWKKRGECFRTGESRTT--------------V- PANTR8_151_PE26 NOISO RLNMKRKHYVRGQALRSRLLRKQAWKQKWRKKGECFGGGGATVT--------------TK PEDHC_890_PE62 NOISO KLNLEKKTYARGKKKFN---FSKYKKQKWKKDKKALNSERESG---------------GI PHPAT1_665_PE34 NOISO KLNINGRGGRRKFTNGIRAKRPSVYGR------RKTFKRYKKTSQ------D------DG PIG4_1_PE21 NOISO RLNMKQKRYVRGLAPRSRLLRRQVWKQKWQKKGESFGGGQPRAT--------------AK PIG4_1_PE7 NOISO RLNMKQKRYVRGLAPRSRLLRRQVWKQKWQKKGESFGGGQPRAT--------------AK PONPY8_159_PE8 NOISO RLNMKQKHYVRGRALRGRLLRKQAWKQKWRKKGECFGGGGATVE--------------IK POPTR_2_PE618 NOISO KLNLNHGRRKFVN--RK-GK----KKSSYASSSRGFYRRSKRKSK------G------EG PTEVAGS_3119_PE13 NOISO RLNMKRKCHVRGPALRGHLLRKQVYKQKWQKKRECFGGGQPRTT--------------AK RAT7_PE1328 ENSRNOG00000032446 RLNMKTKCFVRVGASRGRLLRKQVWKQKWKKKQEWFGKSGPRAT--------------VK RAT7_PE1329 ISOFORMIN RLNMKTKCFVRVGASRGRLLRKQVWKQKWKKKQEWFGKSGPRAT--------------VK SORARGS_5380_PE3 NOISO RLNLKHKHYMRGPALRGRFLRRQVWKQKWQKKEG-LDRVRRRPM--------------SQ SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO RLNMKHKRYVWGGALRGRLLRRQAWKQKWQKKGECFGGGGARPP--------------AK TARSYGS_5559_PE1 NOISO RLNMKQKRYMRGRALGGRLLRKQAWKQKWQKKRECFGGGGPRAS--------------VK TETNG21RD_PE128 ENSTNIG00000017539 KINLKKKSHVKGYALRGVGLRKQLYMEKFQLKGERFGGGGRHFGRGRRGGFRGG-FGRPG TETNG21RD_PE129 ISOFORMIN KINLKKKSHVKGYALRGVGLRKQLYMEKFQLKGERFGGGGRHF-------------GRPG TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------------------------------------MAM------G------ES XENTR1850_PE1 NOISO RINLKKKSHVKSFALNGQRLRKQMWKQKWQKKGEQFGGGGKHFN-------------RGG MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO LKCFKCGDIGHYSKHCNKSNDLVPLEDIGEED-------SPY-LTLEEAEQLALEKKEKA AEDAE_4224_PE7 NOISO LTCFQCGGVGHMARSCKVK-GEQLL----PLEADDT-EESPF-PTLEEAESMANAQSLAV AILMEGL192891_1_1_PE17 NOISO NSCFQCGQLGRWSSQCPQ---SEPTLDPQKSS-EDEEDVQTQ-LTLEEVVRRTGT----A ANOCA1050_PE2 NOISO DTCFRCGEVGHWASQCKGKVINTDE------NGCDAEEEVPL-LTLEEVAQMTNT----A ANOGA_1_PE1398 AGAP005917 LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_2_PE1395 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_3_PE1398 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_4_PE1398 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_5_PE1397 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_6_PE1398 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_7_PE1397 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_8_PE1398 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV ANOGA_9_PE1398 HAPLOTYPE LTCFQCGGTGHMAFQCKKPLEDKLL----PYDADTI-EESSF-PTLEEAEAMANSRTLAV APIME_119_PE11 NOISO STCFKCQNIGHFAKNCPNVKNDDLI----PINE--IDESSQF-PTLEEAEQMASQNAIIA APIME_119_PE12 NOISO STCFKCQNIGHFAKNCPNVKNDDLI----PINE--IDESSQF-PTLEEAEQMASQNAIIA ARALY_1_PE2902 NOISO ES--------------------------------LLEEESDL----QKQVEE-------- ARATH_1_PE3672 NOISO ES--------------------------------LLEEESDL----QKQIED-------- BOVIN14_1_PE17 ISOFORMIN DSCSQHGQLSQWASRCPQ---PEPLLVPQKDV-KVADGAQTQ-PTLQEASLRTGA----A BOVIN14_1_PE18 ENSBTAG00000010276 DSCSQHGQLSQWASRCPQ---PEPLLVPQKDV-KVADGAQTQ-PTLQEASLRTGA----A BOVIN14_1_PE19 ISOFORMIN DSCSQHGQLSQWASRCPQ---PEPLLVPQKDV-KVADGAQTQ-PTLQEASLRTGA----A BRADI_5_PE1289 NOISO DE--------------------------------E----GDF----VAEALLERE----- CALJA16_53_PE9 NOISO DSCFLNGRFDHRAPQCPQP----------------------------------------- CANFA13_42_PE41 NOISO DSCFRCGQLGHWSSQCPQ---PKPTWGPQTSS-EKEEEVQPQ-LTPEEGPRRTGT----T CAVPO95_4_PE36 NOISO KSHFQSEQFGYWKSQCPQLSIPGPGSTPQKEGGDDKDDVQSS-PTLKEVTQRIDA----A CIOIN3Q_5_PE89 NOISO DKCFKCGETGHWASKCTGKFKGKAKEQD-------AENKASWDKFLENLVS--------- CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO LTCFQCGGVGHMARQCKVK-GEQLL----PLGAEGE-EESPF-PTLEEAESMAKAKTLVV DANRE19_4_PE9 NOISO DTCYKCGGTGHWAQDCRGKVPVNTSA--EQQETPVEEEEFEL-PTLEEVARATGT----L DASNOGS_5448_PE2 NOISO DSCFCCGQPGHWASQCPQP----------------------------------------- DIPORGS_5063_PE4 NOISO DSCFQCGKLGHWASHCPQP----------------------------------------- DROME3L_9_PE65 NOISO LTCFQCGGVGHFAQQCKVK-GDSLL----PLSAQLEEDPSPF-PTLAEAQEMASQGAVVA ECHTEGS_6465_PE2 NOISO D-SASLGHSRHWASQSPQSXXXXXXXXXX------------------------------- ERIEUGS_6628_PE4 NOISO NCCFQCGKLGHWASQCSQP----------------------------------------- FELCAGS_5236_PE10 NOISO XXXXXXXXX------------------------------------------XXXX----X FUGRU37_1_PE108 ENSTRUG00000012749 DTCYKCGETGHWAIDCKGRAPPPSA----PEDPPAVEEPFEL-PTLEEVARATGT----L FUGRU37_1_PE109 ISOFORMIN DTCYKCGETGHWAIDCKGRAPPPSA----PEDPPAVE----------------------- FUGRU37_1_PE110 ISOFORMIN DTCYKCGETGHWAIDCKGRAPPPSA----PEDPPAVEEPFEL-PTLEEVARATGT----L GASACGROUPIII_7_PE38 NOISO DTCFKCGGTGHWSMDCKGLAPPTPVA----EDQPAEEEPFEL-PTLEEVARATGT----L GORGO8_151_PE6 NOISO ESCFLNEQFDRWAAQCPRP----------------------------------------- HORSE9_86_PE8 NOISO DSCFWCGQLGHWASQCTH---PEPTLASQKEGGEDEGDTQTL-PTLEEVAQQPGT----A HS8_PE3578 ISOFORMIN ESCFLNEQFDHWAAQCPRP----------------------------------------- HS8_PE3579 ENSG00000160957 ESCFLNEQFDHWAAQCPRP----------------------------------------- LOXAF185_PE18 NOISO NSCFRCGQLGHWASQCHQ---PEPA--PAQKKGTRDEGTQLL-SILEEVAQKTGA----A MACEUGS_7560_PE2 NOISO ESCFRCGDAGHWASQCPGRGSEE--------EAV-------------------------- MACMU8_150_PE22 NOISO ESCFLNEQFDHWAPQCPQP----------------------------------------- MAIZE_2_PE7014 NOISO DE--------------------------------E----GDF----VAEAMIERE----- MICMUGS_3858_PE24 NOISO KACLSCGQFSHWAPQCPQP----------------------------------------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN ESCFRCGGAGHWASQCPGRDSKT--------LEEQEEEEPPL-PTLEEVAQRVSS----A MONDO3_446_PE29 ENSMODG00000011014 ESCFRCGGAGHWASQCPGRESKK--------WSRQSQ----------------------- MOUSE15_PE705 ENSMUSG00000033762 DTCFRCGQFGHWASQCSQ---PGPTLTVQEEG--DRDDKQPI-STLEEVAQRTGT----A MOUSE15_PE706 ISOFORMIN DTCFRCGQFGHWASQCSQ---PGPTLTVQEEG--DRDDKQPI-STLEEVAQRTGT----A MYOLUGS_4426_PE2 NOISO DSCFRCGQLGHWASQCPRP----------------------------------------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO DSCFRCGQPGHWASHCPQP----------------------------------------- ORNANCONTIG341_PE6 ENSOANG00000003526 DTCFRCGGRGHWAAQCRRRGAPSH--QPPEQESSHAQEEPPL-PTLEEVAQRTNT----A ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO DE--------------------------------E----GDL----VAEALLERE----- ORYSJ_7_PE4100 NOISO DE--------------------------------E----GDL----VAEALLERE----- OSTLU_4_PE413 NOISO ------------------------------------------------------------ OTOGAGS_5082_PE6 NOISO TACLSSGQLGHWAQQCPQS----------------------------------------- PANTR8_151_PE26 NOISO ESCFLNEQFDHWAAQCPLP----------------------------------------- PEDHC_890_PE62 NOISO LECFTCGEKGHFSRNCKKNKEDKLL---DVDDEFENDCDVHL-PTLEEARALAEE----K PHPAT1_665_PE34 NOISO EP--------------------------------VID---------------EGD----- PIG4_1_PE21 NOISO DSCFRCGQLGHWASQCPQ---PGPEPAPQKEGGKDEDDTGTL-PMLEEVPQRTGT----T PIG4_1_PE7 NOISO DSCFRCGQLGHWASQCPQ---PGPEPAPQKEGGKDEDDTGTL-PMLEEVPQRTGT----T PONPY8_159_PE8 NOISO ESCFLNEQSDHRAAQCPQP----------------------------------------- POPTR_2_PE618 NOISO DV--------------------------------EMESVCDE----EGLVTEIGQ----- PTEVAGS_3119_PE13 NOISO DSCFRCGQLGHWASQCPQT----------------------------------------- RAT7_PE1328 ENSRNOG00000032446 DTCFRCGQFGHWASQCSQ---PGSTLTIQPKG--DRNDKHPI-STLGGVAQKTGT----T RAT7_PE1329 ISOFORMIN DTCFRCGQFGHWASQCSQ---PGSTLTIQPKG--DRNDKHPI-STLGGVAQKTGT----T SORARGS_5380_PE3 NOISO DSCFKCGQLGHWGSECPQH----------------------------------------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO DSCFQSGPFGRWVPQCSKP----------------------------------------- TARSYGS_5559_PE1 NOISO ESCFPCEQFGHWASQCPQP----------------------------------------- TETNG21RD_PE128 ENSTNIG00000017539 DTCYKCGGTGHWAMHCKGPAPAPSV----PEDPPADEEPFEL-PTLEEVARATGT----L TETNG21RD_PE129 ISOFORMIN DTCYKCGGTGHWAMHCKGPAPAPSV----PEDPPADEEPFEL-PTLEEVARATGT----L TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO -----------------------------------LQ--TRA----RERVTMHRQ----- XENTR1850_PE1 NOISO DTCFRCGGIGHWASQCPGSVPVVRQE----VVEIEEEEEVSL-PTLEDVARMTNT----Q MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO HCKKWARES-K------D--------------QNYS--------------I--------- AEDAE_4224_PE7 NOISO HSNKIEKLPAASNPLWKLDETD-----------TPED-----------NEY--------- AILMEGL192891_1_1_PE17 NOISO SCQLPVSEK-------------------DTEPAGPE--------------P--------- ANOCA1050_PE2 NOISO YSKVS------------------------------G--------------E--------- ANOGA_1_PE1398 AGAP005917 HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_2_PE1395 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_3_PE1398 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_4_PE1398 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_5_PE1397 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_6_PE1398 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_7_PE1397 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_8_PE1398 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD ANOGA_9_PE1398 HAPLOTYPE HSNRIERLPPVANPVWKEQEQEDLPAEEEVGEPGKEEPSTLPV----EDDLDEPMEQESD APIME_119_PE11 NOISO HANRIDRLPEIPSFSSKMYEST--VNEEIKDKTND------------DDDL--------- APIME_119_PE12 NOISO HANRIDRLPEIPSFSSKMYEST--VNEEIKDKTND------------DDDL--------- ARALY_1_PE2902 NOISO ------------------------------EANGFI------------SSV--------- ARATH_1_PE3672 NOISO ------------------------------EANGFI------------SSV--------- BOVIN14_1_PE17 ISOFORMIN CCQVSAGEE-------------------DAEPGAPE--------------L--------- BOVIN14_1_PE18 ENSBTAG00000010276 CCQVS-GEE-------------------DAEPGAPE--------------L--------- BOVIN14_1_PE19 ISOFORMIN CCQVSAGEE-------------------DAEPGAPE--------------L--------- BRADI_5_PE1289 NOISO -----------------------------KNGAGGG------------NGV--------- CALJA16_53_PE9 NOISO -----GNEE-------------------DTDPAWSE--------------P--------- CANFA13_42_PE41 NOISO SCRLPVSEE-------------------DTEPAGPE--------------R--------- CAVPO95_4_PE36 NOISO CCYLPG--K-------------------DPEPTGPE--------------L--------- CIOIN3Q_5_PE89 NOISO ------------------------------DPAS-E------------------------ CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO HSNKMQNLPAVANPLWKEEGEPSTSKAEPTDQPEEVD-----------DEY--------- DANRE19_4_PE9 NOISO RSEPIVAPPSA------DGDS------SEKEEQGAE--------------I--------- DASNOGS_5448_PE2 NOISO -----AREV-------------------DQQPEPPR--------------M--------- DIPORGS_5063_PE4 NOISO ------AGE-------------------DTEPTEPQ--------------L--------- DROME3L_9_PE65 NOISO HSRNISRLPQAANAAILQGDELNESEEDDQESSGDEEVQQHPDPNWSSDEMDVDFEALDA ECHTEGS_6465_PE2 NOISO -----------------------------------X--------------X--------- ERIEUGS_6628_PE4 NOISO -----ADEE-------------------GTELMGPK--------------L--------- FELCAGS_5236_PE10 NOISO XXXXXXSEK-------------------DPEPAGPE--------------L--------- FUGRU37_1_PE108 ENSTRUG00000012749 RSG-----------------------------PLDE--------------V--------- FUGRU37_1_PE109 ISOFORMIN ----------------------------------DE--------------V--------- FUGRU37_1_PE110 ISOFORMIN RSG-----------------------------PLDE--------------V--------- GASACGROUPIII_7_PE38 NOISO QPRPHETEV--------------------DSEHKDE--------------V--------- GORGO8_151_PE6 NOISO -----ASEE-------------------DTDPVGPE--------------P--------- HORSE9_86_PE8 NOISO YCQLPG-KE-------------------DTEPAGPE--------------L--------- HS8_PE3578 ISOFORMIN -----ASEE-------------------DTDAVGPE--------------P--------- HS8_PE3579 ENSG00000160957 -----ASEE-------------------DTDAVGPE--------------P--------- LOXAF185_PE18 NOISO HCKLPD--E-------------------DTGSARPH--------------T--------- MACEUGS_7560_PE2 NOISO ----S------------------------------T--------------H--------- MACMU8_150_PE22 NOISO -----VSEE-------------------DTDPAGPE--------------P--------- MAIZE_2_PE7014 NOISO -----------------------------KKRAGGD------------GGV--------- MICMUGS_3858_PE24 NOISO -----VDEE-------------------DTRPAGPE--------------P--------- MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN ACRVL------------------------------E--------------E--------- MONDO3_446_PE29 ENSMODG00000011014 ----P------------------------------E--------------E--------- MOUSE15_PE705 ENSMUSG00000033762 SCHHSG--E-------------------ETQPAAPE--------------L--------- MOUSE15_PE706 ISOFORMIN SCHHSG--E-------------------ETQPAAPE--------------L--------- MYOLUGS_4426_PE2 NOISO -----AGEE-------------------DTDPAGSE--------------L--------- NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO -----GDRD-------------------REPPELE------------------------- ORNANCONTIG341_PE6 ENSOANG00000003526 YSKIPG-DE-------------------GTEVTGSE--------------L--------- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO -----------------------------KQAA--S------------DSV--------- ORYSJ_7_PE4100 NOISO -----------------------------KQAA--S------------DSV--------- OSTLU_4_PE413 NOISO --------------------------------------------------M--------- OTOGAGS_5082_PE6 NOISO -----TAEE-------------------DTESARPX--------------X--------- PANTR8_151_PE26 NOISO -----ASEK-------------------DTDPVGPE--------------P--------- PEDHC_890_PE62 NOISO GKQYQ---------------------------FNHK--------------N--------- PHPAT1_665_PE34 NOISO -----------------------------NNSPEDL------------ERC--------- PIG4_1_PE21 NOISO CCQLPG-EE-------------------DTEPAGPE--------------L--------- PIG4_1_PE7 NOISO CCQLPG-EE-------------------DTEPAGPE--------------L--------- PONPY8_159_PE8 NOISO -----ASEE-------------------DTHPVGPE--------------L--------- POPTR_2_PE618 NOISO -----------------------------QKPKKGC------------ELI--------- PTEVAGS_3119_PE13 NOISO -----AGEE-------------------NA------------------------------ RAT7_PE1328 ENSRNOG00000032446 SCNHSG--E-------------------ETEPAGPV--------------L--------- RAT7_PE1329 ISOFORMIN SCNHSG--E-------------------ETEPAGPV--------------L--------- SORARGS_5380_PE3 NOISO -----EDVE-------------------TSNLQCPG--------------S--------- SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO -----VGEN--------------------TGLAGPE--------------L--------- TARSYGS_5559_PE1 NOISO -----XXXX-------------------XXXXXXXX--------------X--------- TETNG21RD_PE128 ENSTNIG00000017539 RPQPTAAAAS------------------TSEEPSDE--------------V--------- TETNG21RD_PE129 ISOFORMIN RPQPTAAAAS------------------TSEEPSDE--------------V--------- TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO -----------------------------GRVKFDG------------ELI--------- XENTR1850_PE1 NOISO LQSTSAEVPSG-------------------WCQGPV--------------A--------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

ACYPI_11004_PE3 NOISO --------E---YPPILED-------------------------ISK-SENISPVYQLKD AEDAE_4224_PE7 NOISO -----EYLPEEPSPPAETKPNYIGHVIPTDFLKKSGILELTVM--N--KDKVGSLYQLNP AILMEGL192891_1_1_PE17 NOISO --------LVTVERPVPQA-------------------------HCPS-PIVPPLYPPGP ANOCA1050_PE2 NOISO --------KDRLEGPTYEP-------------------------PPPP-KPIEPLYGLGP ANOGA_1_PE1398 AGAP005917 EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_2_PE1395 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_3_PE1398 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_4_PE1398 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_5_PE1397 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_6_PE1398 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_7_PE1397 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_8_PE1398 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG ANOGA_9_PE1398 HAPLOTYPE EHQ--KETEQNAAASQPAAPAYIGHKIPEEFLKQSGLLEVTVS--GGFKGTVEPLYQQRG APIME_119_PE11 NOISO ------------WEPIEDEEILCGHKIPDDLIQKLL---------PPEIGTVQPLYKLKD APIME_119_PE12 NOISO ------------WEPIEDEEILCGHKIPDDLIQKLL---------PPEIGTVQPLYKLKD ARALY_1_PE2902 NOISO ------------EDAILAV---------------------------KTEASDENL----- ARATH_1_PE3672 NOISO ------------EDAILAV---------------------------KTEASDENL----- BOVIN14_1_PE17 ISOFORMIN --------LVPTGQSVSRM-------------------------PCPP-LSVPPLYPPGP BOVIN14_1_PE18 ENSBTAG00000010276 --------LVPTGQSVSRM-------------------------PCPP-LSVPPLYPPGP BOVIN14_1_PE19 ISOFORMIN --------LVPTGQSVSRM-------------------------PCPP-LSVPPLYPPGP BRADI_5_PE1289 NOISO ------------LEAVEVA---------------------------REDPSEQNL----- CALJA16_53_PE9 NOISO --------LVPVPQPVPEV-------------------------PGLA-PTVLPLYSLGP CANFA13_42_PE41 NOISO --------LVTTERPVLQA-------------------------PCPP-PTVPPLYPPGP CAVPO95_4_PE36 NOISO --------QAPNT-----------------------------------VPSVLPLYPLGP CIOIN3Q_5_PE89 NOISO --------PLSYSSQQFQQ-------------------------TQITLEHAEPLYTEDS CULQU_306_PE9 NOISO ------------------------------------------------------------ CULQU_602_PE10 NOISO -----EDVPDEPSQPEQLPASYIGHAIPADFLKKSGILEYTVG--N--KDQSQSLYQLLP DANRE19_4_PE9 NOISO --------LLNIIRPDYER-------------------------PAPP-PPMEPLYKLKD DASNOGS_5448_PE2 NOISO ------------------------------------------------HPTVPPLYPPRP DIPORGS_5063_PE4 NOISO --------QAT-------------------------------------LPTVRPLYPPGP DROME3L_9_PE65 NOISO AVEASLSQPVSQEKAASPIKTYVGHKIPEEFLKQAGLDTTASSSNRSQHGGVKPLYDLLP ECHTEGS_6465_PE2 NOISO --------XXXXXXXXXXX-------------------------XXXPAPMVPPLYPPGP ERIEUGS_6628_PE4 NOISO --------SVPMEQPVPEA-------------------------PCPP-PAVPPLYPLGP FELCAGS_5236_PE10 NOISO --------LVTVEQPVPRV-------------------------PCLP-PTVPPLYPPGP FUGRU37_1_PE108 ENSTRUG00000012749 --------LLNVMRPDYER-------------------------PAPP-PPVEPLYDLDD FUGRU37_1_PE109 ISOFORMIN --------LLNVMRPDYER-------------------------PAPP-PPVEPLYDLDD FUGRU37_1_PE110 ISOFORMIN --------LLNVMRPDYER-------------------------PAPP-PPVEPLYDLDD GASACGROUPIII_7_PE38 NOISO --------LLNVIRPDYER-------------------------PAPP-PPMEPLYPLTD GORGO8_151_PE6 NOISO --------LVPSPQPVPEV-------------------------PSLD-PTVLPLYSLGP HORSE9_86_PE8 NOISO --------LAPTQQPVPRA-------------------------PSPP-PTMPPLYLREP HS8_PE3578 ISOFORMIN --------LVPSPQPVPEV-------------------------PSLD-PTVLPLYSLGP HS8_PE3579 ENSG00000160957 --------LVPSPQPVPEV-------------------------PSLD-PTVLPLYSLGP LOXAF185_PE18 NOISO ------------------------------------------------PNVVLPLYLPGP MACEUGS_7560_PE2 NOISO --------LVPPRKPVFDP-------------------------PLLP-RAVEPLYGLGP MACMU8_150_PE22 NOISO --------LVPAPQPVPGV-------------------------PGLA-STMLPLYSLGP MAIZE_2_PE7014 NOISO ------------LEAVEAA---------------------------REDPSEQNL----- MICMUGS_3858_PE24 NOISO --------K---------V-------------------------PHLA-PAVLPLYPLRP MICSR_3_PE377 NOISO ------------------------------------------------------------ MONDO3_446_PE28 ISOFORMIN --------PVPPKGPECKA-------------------------PELP-SAVEPLYGLGP MONDO3_446_PE29 ENSMODG00000011014 --------PVPPKGPECKA-------------------------PELP-SAVEPLYGLGP MOUSE15_PE705 ENSMUSG00000033762 --------QVPHC-----------------------------------PTPMSPLYPPGP MOUSE15_PE706 ISOFORMIN --------QVPHC-----------------------------------PTPMSPLYPPGP MYOLUGS_4426_PE2 NOISO --------LVPMEAPVPGG-------------------------PCPS-PAVPPLYLPGP NEMVE_4617_PE16 NOISO ------------------------------------------------------------ OCHPRGS_3806_PE4 NOISO --------------------------------------------SPLP-PPVPPLYPMEP ORNANCONTIG341_PE6 ENSOANG00000003526 --------LVPTERPAHVA-------------------------PAPP-PAVKPLYGLGP ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ------------LEAVESV---------------------------REDPSEQNL----- ORYSJ_7_PE4100 NOISO ------------LEAVESV---------------------------REDPSEQNL----- OSTLU_4_PE413 NOISO ------------QAAVLRA---------------------------KSDPSEANL----- OTOGAGS_5082_PE6 NOISO --------XXXXXXXXXXX-------------------------XXXX-XXXXXXXXXXX PANTR8_151_PE26 NOISO --------LVPSPQPVPEV-------------------------PSLD-PTVLPLYSLGP PEDHC_890_PE62 NOISO --------IFNLQEPSEEI---------------------------INFGKVEPLYELKE PHPAT1_665_PE34 NOISO ------------KEAANKA---------------------------LLDPTEENL----- PIG4_1_PE21 NOISO --------SVPMQSSMPRA-------------------------PCPPPPPVPPLYPLGP PIG4_1_PE7 NOISO --------SVPMQSSMPRA-------------------------PCPPPPPVPPLYPLGP PONPY8_159_PE8 NOISO --------LVPAPQPVPEV-------------------------PSLD-PAVLPLYSLGP POPTR_2_PE618 NOISO ------------DEAVLEV---------------------------QNEASDENL----- PTEVAGS_3119_PE13 NOISO ---------------QPGP-------------------------PCPP-QPMPPLYQPGC RAT7_PE1328 ENSRNOG00000032446 --------PVPHC-----------------------------------PTPVLPLYPPGP RAT7_PE1329 ISOFORMIN --------PVPHC-----------------------------------PTPVLPLYPPGP SORARGS_5380_PE3 NOISO -----------PQRHLPEA-------------------------PCP--SPMLPLYQPAP SORBI_7_PE1508 NOISO ------------------------------------------------------------ SPETRGS_4687_PE12 NOISO --------QVC---------------------------------SPPS-PPVLPLYPPGP TARSYGS_5559_PE1 NOISO --------XXXXXXXXXXX-------------------------XXXX-XXXXXXXXXXX TETNG21RD_PE128 ENSTNIG00000017539 --------LLNVIRPDYER-------------------------PAPP-PPVEPLYDLDD TETNG21RD_PE129 ISOFORMIN --------LLNVIRPDYER-------------------------PAPP-PPVEPLYDLDD TRIAD_1_PE1288 NOISO ------------------------------------------------------------ VITVI_1_PE1156 NOISO ------------EAAALEV---------------------------QNEASDEKL----- XENTR1850_PE1 NOISO --------TLNVVRAVYEP-------------------------PEPP-SPMQALYELEP MATCH CONSENSUS ??????????????????????????????????????????????????????L?????

ACYPI_11004_PE3 NOISO N-SIIDTPDEVFEALKLFGHTKFRPGQEKAIMRILSGLSTLVTLSTGSGKS-LCYQLPAY AEDAE_4224_PE7 NOISO DGSLPETPKAVFDALKMFGHQQFRSGQERAVMRVLCGMSTLVTLSTGSGKS-LCYQLPAY AILMEGL192891_1_1_PE17 NOISO SGQVAETPAEVFQALEELGHQAFRPGQERVVMRILSGMSTLLVLPTGAGKS-LCYQLPAL ANOCA1050_PE2 NOISO DAKVKETPPEVFQALAELGFTSFRAGQETAVMRILSGLSTLVVLSTGMGKS-LCYQLPAY ANOGA_1_PE1398 AGAP005917 DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_2_PE1395 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_3_PE1398 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_4_PE1398 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_5_PE1397 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_6_PE1398 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_7_PE1397 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_8_PE1398 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY ANOGA_9_PE1398 HAPLOTYPE DCTVPPTPPEVFEALRMFGHQSFRHGQERAVMRVLCGLSTLVTLSTGAGKS-LCYQLPAY APIME_119_PE11 NOISO DQSCIETPSEVFDALRKFGHTTFRHGQEKAIMRILSGQSTLVTLSTGSGKS-LCYQLPAY APIME_119_PE12 NOISO DQSCIETPSEVFDALRKFGHTTFRHGQEKAIMRILSGQSTLVTLSTGSGKS-LCYQLPAY ARALY_1_PE2902 NOISO ----------TKLLNLVYGYDSFRDGQLEAIKMILGGSSTMLVLPTGAGKS-LCYQIPAM ARATH_1_PE3672 NOISO ----------TKLLNLVYGYDSFRDGQLQAIKMILGGSSTMLVLPTGAGKS-LCYQIPAM BOVIN14_1_PE17 ISOFORMIN SGQVADTPAEVFQALEQLGHHAFYPGQERVVMRVLSGMSTLLVLPTGAGKS-LCYQLPAL BOVIN14_1_PE18 ENSBTAG00000010276 SGQVADTPAEVFQALEQLGHHAFYPGQERVVMRVLSGMSTLLVLPTGAGKS-LCYQLPAL BOVIN14_1_PE19 ISOFORMIN SGQVADTPAEVFQALEQLGHHAFYPGQERVVMRVLSGMSTLLVLPTGAGKS-LCYQLPAL BRADI_5_PE1289 NOISO ----------ESLLRLVFGHDSFREGQLEAIQNVVLGESTVLVLPTGAGKS-LCYQLPAM CALJA16_53_PE9 NOISO SGQVAETPAEVFHALEQLGHRAFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL CANFA13_42_PE41 NOISO SGQVAETPAEVFQALEQLGHRAFRPRQEQVVMRVLSGMSTLLVLPTGAGKS-LCYQLPAL CAVPO95_4_PE36 NOISO SGQVAETPAEVFQALEQLGHKAFRPGQERTIMRILSGISTLLVLPTGAGKS-LCYQLPAL CIOIN3Q_5_PE89 NOISO -----FNEDEVYSVLKKFGFSEFRTGQLQAMKRILLGKPTLLVLSTGSGKS-LCYQLPAY CULQU_306_PE9 NOISO ---------GVFDALKQFGHANFRAGQERAVMRVLCGMSTLVTLSTGSGKS-LCYQLPAY CULQU_602_PE10 NOISO DGSLPPTPPEVFDALKQFGHANFRAGQERAVMRVLCGMSTLVTLSTGSGKS-LCYQLPAY DANRE19_4_PE9 NOISO DGKVQDVPPEVYEALRDFGYKSFRPGQEAAIMRILSGLSTLVVLSTGMGKS-LCYQLPAY DASNOGS_5448_PE2 NOISO SGQVVETPAEVFQALEQLGHQAFRPGQERAVMRILSGLSTLLVLPTGAGKS-LCYQLPAL DIPORGS_5063_PE4 NOISO SGQVAETPLEVFQALKQLGHQAFRPGQEQAIMRILSGISTLLVLPTGAGKS-LCYQLPAL DROME3L_9_PE65 NOISO DGSVQDTTPEVLEALHMFGHTNFRKGQDRAIMRTLSGLSSLVTLSTGSGKS-LCYQLPAY ECHTEGS_6465_PE2 NOISO SKQVAETPPEVLQALRQLGHQAFRPWQEQAVMRVLSGISTLLVLPTGTGKS-LCYQLPAL ERIEUGS_6628_PE4 NOISO SGQVAETPVEVFQALEHLGHQTFRPGQEQVIMRILSGVSTLLVLPTGAGKS-LCYQLPAL FELCAGS_5236_PE10 NOISO SGQVAETPAEVFQALEQLGHRAFRPGQEHAVMRILSGISTLLVLPTGAGKS-LCYQLPAL FUGRU37_1_PE108 ENSTRUG00000012749 AGNVRGTPADVHAALRELGYQSFRPGQEEAIMRILSGLSTLVVLSTGMGKS-LCYQLPAY FUGRU37_1_PE109 ISOFORMIN AGNVRGTPADVHAALRELGYQSFRPGQEEAIMRILSGLSTLVVLSTGMGKS-LCYQLPAY FUGRU37_1_PE110 ISOFORMIN AGNVRGTPADVHAALRELGYQSFRPGQEEAIMRILSGLSTLVVLSTGMGKS-LCYQLPAY GASACGROUPIII_7_PE38 NOISO DGKVQETPAEVYAALTEIGYQSFRPGQEEAIMRILSGLSTLVVLSTGMGKS-LCYQLPAF GORGO8_151_PE6 NOISO SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL HORSE9_86_PE8 NOISO SGQVAETPAEVFQALEQLGYQAFRPGQEQAVMRILSGMSTLLVLPTGAGKS-LCYQLPAL HS8_PE3578 ISOFORMIN SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL HS8_PE3579 ENSG00000160957 SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL LOXAF185_PE18 NOISO LGQVAETPPEVFQALGQLGYQAFRPGQEQAVMRILSGISTLLVLPTGAGKS-LCYQLPAL MACEUGS_7560_PE2 NOISO SGQVAETPSEVFETLTQFGHHTFRPGQEAAIMRILSGLSTLVVLPTGMGKS-LCYQLPAL MACMU8_150_PE22 NOISO SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL MAIZE_2_PE7014 NOISO ----------ENLLRIIYGYNSFREGQLEAIQKVVAGESTMLVLPTGAGKS-LCYQVPAM MICMUGS_3858_PE24 NOISO SGQVAETPTEVFQALEQLGHQAFRPGQEHTVMRILSGISTLLVLPTGAGKS-LCYQLPAL MICSR_3_PE377 NOISO -----------------------------------------------------------M MONDO3_446_PE28 ISOFORMIN SGQVAETPLEVFETLTRFGYHTFRPGQEAAIMRILSGLSTLVVLPTGMGKS-LCYQLPAL MONDO3_446_PE29 ENSMODG00000011014 SGQVAETPLEVFETLTRFGYHTFRPGQEAAIMRILSGLSTLVVLPTGMGKS-LCYQLPAL MOUSE15_PE705 ENSMUSG00000033762 LGQVAETPAEVFQALERLGYRAFRPGQERAIMRILSGISTLLVLPTGAGKS-LCYQLPAL MOUSE15_PE706 ISOFORMIN LGQVAETPAEVFQALERLGYRAFRPGQERAIMRILSGISTLLVLPTGAGKS-LCYQLPAL MYOLUGS_4426_PE2 NOISO LGQVAATPVEVLQALEQLGHRAFRPGQEHAVMRILSGMSTLLVLPTGAGKS-LCYQLPAL NEMVE_4617_PE16 NOISO -------------------------------MRILSGMSSLVVLSTGAGKS-LCYQLPAY OCHPRGS_3806_PE4 NOISO SKQMAETPAEVYQALEELGYQAFRPGQERAIMRILSGVSTLLVLPTGAGKS-LCYQLPAL ORNANCONTIG341_PE6 ENSOANG00000003526 SGQVKETPAEVFQALSQLGHKTFRPGQEAAVMRILSGESRFPLNPPSPR---RCY--PXL ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO ----------KSLLNAAYGHDSFRQGQLEAIQQIVAGESTMLVLPTGAGKS-LCYQVPAM ORYSJ_7_PE4100 NOISO ----------KSLLNAAYGHDSFRQGQLEAIQQIVAGESTMLVLPTGAGKS-LCYQVPAM OSTLU_4_PE413 NOISO ----------TEVLNRGFGHEQFRPGQLEIVQRVLRGENTLALLPTGAGKS-LTYQLPAL OTOGAGS_5082_PE6 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX PANTR8_151_PE26 NOISO SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL PEDHC_890_PE62 NOISO NGDVIETPPEVYEALEKFGHTYFRPGQEETIMRMLSGLSTLLIISTGGGKS-LCYQLPAY PHPAT1_665_PE34 NOISO ----------SFILKRVFGHETFRQGQLVAIQRVLARKSTLLVLPTGAGKS-LSYQLPAY PIG4_1_PE21 NOISO SGQVADTPAEVFQALEQLGHQAFNPGQEHVVMRILSGMSTLLVLPTGGGKS-LCYQLPAL PIG4_1_PE7 NOISO SGQVADTPAEVFQALEQLGHQAFNPGQEHVVMRILSGMSTLLVLPTGGGKS-LCYQLPAL PONPY8_159_PE8 NOISO SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL POPTR_2_PE618 NOISO ----------ARLLNVMYGYDSFREGQLEAIKMVLDGKSTMLVLPTGAGKS-LCYQIPAT PTEVAGS_3119_PE13 NOISO SGQVAETPAEVFQALKQLGHQAFRPGQERAVMQVLSGMSTLLVLPTGAGKS-LCYQLPAL RAT7_PE1328 ENSRNOG00000032446 LGQVADTPAEVFQVLEQLGHHTFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL RAT7_PE1329 ISOFORMIN LGQVADTPAEVFQVLEQLGHHTFRPGQERAVMRILSGISTLLVLPTGAGKS-LCYQLPAL SORARGS_5380_PE3 NOISO SGEMPETPAEVFQALHHLGHQAFRPGQEQAIMRILCGMSTLLVLPTGAGKS-LCYQLPAL SORBI_7_PE1508 NOISO ----------------------------------------MLVLPTGAGKS-LCYQVPAM SPETRGS_4687_PE12 NOISO SGQVAETPAEVFQALEQLGYRAFRPGQEHAVMRILSGISTLLELPTGAGKS-LCYQLPAL TARSYGS_5559_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TETNG21RD_PE128 ENSTNIG00000017539 AGKVRGTTAEVYEALRELGYQSFRPGQEEAIMRILSGLSTLVVLSTGMGKS-LCYQLPAY TETNG21RD_PE129 ISOFORMIN AGKVRGTTAEVYEALRELGYQSFRPGQEEAIMRILSGLSTLVVLSTGMGKS-LCYQLPAY TRIAD_1_PE1288 NOISO -------------SLKEFGYCAFKTGQRKVISRILCGMSTLAILPTGGGKS-LCYQLPAR VITVI_1_PE1156 NOISO ----------VKLLGLTHGYDSFRDGQLEAIRMVLEGKSTMLVLPTGAGKS-LCYQLPAL XENTR1850_PE1 NOISO DGKVKETPAEVYDTLSELGYSSFRPGQEQAVMRILSGLSSLVILSTGMGKS-LCYQLPAY MATCH CONSENSUS ??????????V???L???G???FR?GQ?????R?L?G?STL??L?TG?GKS?LCYQLPA?

ACYPI_11004_PE3 NOISO LFSKKSKCITLVISPLISLMEDQVGGISA--VNIACLHNSQTPKERDIIMEKLANGELSI AEDAE_4224_PE7 NOISO LYRKHRKCITLVISPLVSLMEDQVHGVPG-FLNAQCLHMNQSPKVRARTMDAITNGELDV AILMEGL192891_1_1_PE17 NOISO LYARRSPCLTLVISPLLSLMDDQMSGLPP-CLKAACIHSGMTRKQQESALKKVQAAQVHV ANOCA1050_PE2 NOISO LYSKRSTCITLVISPLVSLMDDQVSGLPQ-HLKAVCIHSNMSKTQREAAMEKVKAGKVHV ANOGA_1_PE1398 AGAP005917 LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_2_PE1395 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_3_PE1398 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_4_PE1398 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_5_PE1397 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_6_PE1398 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_7_PE1397 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_8_PE1398 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV ANOGA_9_PE1398 HAPLOTYPE LYRKNRSCITLVISPLVSLMEDQVHGMPD-FLNAHCLHTNQTPKVRDRTMQAIAAGEVDV APIME_119_PE11 NOISO LYSQYSTCITLVISPLVSLMDDQVTGVPS-FLSAACLHTNQTQKVRDNTMKMIKQGKINI APIME_119_PE12 NOISO LYSQYSTCITLVISPLVSLMDDQVTGVPS-FLSAACLHTNQTQKVRDNTMKMIKQGKINI ARALY_1_PE2902 NOISO IL----PGITLVVSPLVSLMIDQLKHLPS-IIKGGLLSSSQRPEETTETLRKLREGIIKV ARATH_1_PE3672 NOISO IL----PGITLVVSPLVSLMIDQLKHLPS-IIKGGLLSSSQRPEEATETLRKLKEGIIKV BOVIN14_1_PE17 ISOFORMIN LYFRRSPCLTLVISPLTSLMDDQLSGLPP-GLKGACIHSGMTKKQRDSALQKARAARVQV BOVIN14_1_PE18 ENSBTAG00000010276 LYFRRSPCLTLVISPLTSLMDDQLSGLPP-GLKGACIHSGMTKKQRDSALQKARAARVQV BOVIN14_1_PE19 ISOFORMIN LYFRRSPCLTLVISPLTSLMDDQLSGLPP-GLKGACIHSGMTKKQRDSALQKARAARVQV BRADI_5_PE1289 NOISO IL----PGLTLVVSPLLSLMVDQLRKLPA-FLPGGLLASSQTGDEFHETLQRLCAGEIKV CALJA16_53_PE9 NOISO LYAQRSPCLTLVISPLLSLMDDQVSGLPP-CLKAACIHSGMTRKQRESVLQKIQAGQVHM CANFA13_42_PE41 NOISO LYARRSPCLTLVISPLLSLMDDQVSSLPP-CLKGVCIHSGMSQKQRESALQKVHAAQVQL CAVPO95_4_PE36 NOISO LYARRSPCLTLVISPLLSLMDDQLSHLSP-SLKAACLHSGMTRKQRDSVLQKVQAAQVHV CIOIN3Q_5_PE89 NOISO MYAMKRSSITLVISPLVSLMDDQVHGLPK-FLRATRLHSGMTKEQREKSMVEIQNGNVDI CULQU_306_PE9 NOISO LLRKRQNCVTLVISPLVSLMEDQVHGVPN-FLNAQCLHTNQTPKVRERTMAAITAGELDV CULQU_602_PE10 NOISO LLRKRQNCVTLVISPLVSLMEDQVHGVPN-FLNAQCLHTNQTPKVRERTMAAITAGELDV DANRE19_4_PE9 NOISO LYAQRSKSITLVVSPLVSLMDDQLSGLPP-KLKAACIHSNMSAKQREAAIEKVKAGQVHV DASNOGS_5448_PE2 NOISO LYARRSPCLTLVISPLLSLMDDQVAGLPP-GLKAVCVHSGMTPKQRDKVLQKVQMAKVHV DIPORGS_5063_PE4 NOISO LYGQRGPCVTLVVSPLLSLMDDQVSGLPP-CLKVACLHSGMTRKQQESVLKKVQAAQVQV DROME3L_9_PE65 NOISO LYSRKVGAITLVISPLVSLMEDQVTGVPH-FLRAHCLHTNQTAPQRMKIQQMIANGEIDI ECHTEGS_6465_PE2 NOISO LYARRSPCLTLVISPLVALMDDQVLGLPP-GLKAACLHSGLNRKQRESVLQKARTAQVHL ERIEUGS_6628_PE4 NOISO LYARRSSCLTLVVSPLLSLMDDQVSGLPP-GLKAACLHSGMTRKQRDSVLQKVQAAQVHV FELCAGS_5236_PE10 NOISO LYARRSPCLTLVISPLLSLMDDQVSGLPP-CLKAACIHSGMTRKERDSALKKVQAAQVHV FUGRU37_1_PE108 ENSTRUG00000012749 LYAKRSDSITLVISPLVSLMDDQLSGLPA-NLKAACIHSNMTMKQREAAVEKVKSGQVCV FUGRU37_1_PE109 ISOFORMIN LYAKRSDSITLVISPLVSLMDDQLSGLPA-NLKAACIHSNMTMKQREAAVEKVKSGQVCV FUGRU37_1_PE110 ISOFORMIN LYAKRSDSITLVISPLVSLMDDQLSGLPA-NLKAACIHSNMTMKQREAAVEKVKSGQVCV GASACGROUPIII_7_PE38 NOISO LFARRSKSIALVISPLVSLMDDQLSGLPD-NLKAACIHSNMTMKQREAAIEKVKSGQVCV GORGO8_151_PE6 NOISO LYTRRSPCLTLVVSPLLSLMDDQVSGLPP-CLKAACIHSGMTRKQRESVLQKIRAAQVHV HORSE9_86_PE8 NOISO LYARRSPCLTLVISPLLSLMDDQVSGLPP-GLKATCIHSGMTRKQRDTALRKVRAAQVHV HS8_PE3578 ISOFORMIN LYSRRSPCLTLVVSPLLSLMDDQVSGLPP-CLKAACIHSGMTRKQRESVLQKIRAAQVHV HS8_PE3579 ENSG00000160957 LYSRRSPCLTLVVSPLLSLMDDQVSGLPP-CLKAACIHSGMTRKQRESVLQKIRAAQVHV LOXAF185_PE18 NOISO LYAQRSPCLTIVISPLLALMDDQVSRLPP-GLKAACLHSGMNRKQREGVLRKVLAAQVHV MACEUGS_7560_PE2 NOISO LYAQRSCCITLVVSPLVSLMDDQVSGLPR-GLRAVCVHSNMTRKQRETAMEKVMTGKAQV MACMU8_150_PE22 NOISO LYARRSPCLTLVISPLLSLMDDQVSGLPP-CLKAACIHSGMTRKQRESVLQKVRAAQVHV MAIZE_2_PE7014 NOISO IL----PGLTLVVSPLLSLMVDQLMKLPA-FLPGGFLASNQTSDEFHETLQRLRGGEIKV MICMUGS_3858_PE24 NOISO LYSRRSPCLTLVISPLLSLMDDQLSGLPP-CLKAACIHSGMTRKRQESVLQKVRAAQLHV MICSR_3_PE377 NOISO LL----PGLTLVVSPLLALMTDQLHGLPP-ALPGAALRSDQKPAQLFGTLDELRAGRLKV MONDO3_446_PE28 ISOFORMIN LYAQRSCCITLVVSPLLSLMDDQVSGLPP-GLKAVCVHSNMTRKQRETAMEKVMTGKVQV MONDO3_446_PE29 ENSMODG00000011014 LYAQRSCCITLVVSPLLSLMDDQVSGLPP-GLKAVCVHSNMTRKQRETAMEKVMTGKVQV MOUSE15_PE705 ENSMUSG00000033762 LYAQRSPCLTLVVSPLLSLMDDQVSDLPS-CLKAACLHSGMTKKQRESVLKKVRAAQVHV MOUSE15_PE706 ISOFORMIN LYAQRSPCLTLVVSPLLSLMDDQVSDLPS-CLKAACLHSGMTKKQRESVLKKVRAAQVHV MYOLUGS_4426_PE2 NOISO LYAQRSPCLTLVISPLLSLMDDQVSGLPQ-GLKAACVHSGMTRKQRDSALQRARAGQVHV NEMVE_4617_PE16 NOISO MYHKRSPCLTLVISPLVSLMEDQITGLPF-GLKGACLHNNQTKPQRLKILTDITAGKVAV OCHPRGS_3806_PE4 NOISO MFARRSPCLSLVISPLLSLMDDQVSGLPR-SLKAACLHSGMSRKQRDSVLQKVRAAQVHV ORNANCONTIG341_PE6 ENSOANG00000003526 FFTSPHQFFEHLPGPLASVSARQVSGLPP-GLRAACVHSNMSKKQRDLAVEKVKAGQVEV ORNANCONTIG341_PE7 ISOFORMIN ------------------------------------------------------------ ORYSI_7_PE1798 NOISO IL----PGLTLVVSPLLSLMVDQLRKLPA-FLPGGLLASSQTSDEFHDTLQRLRAGEIKV ORYSJ_7_PE4100 NOISO IL----PGLTLVVSPLLSLMVDQLRKLPA-FLPGGLLASSQTSDEFHDTLQRLRAGEIKV OSTLU_4_PE413 NOISO LL----PGLTIVISPLLALMADQMDSLPP-SLPGGALRSDMDRRDMWETLTRLRAGELKV OTOGAGS_5082_PE6 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PANTR8_151_PE26 NOISO LYSRRSPCLTLVVSPLLSLMDDQVSGLPP-CLKAACIHSGMTRKQRESVLQKIRAAQVHV PEDHC_890_PE62 NOISO LYAKRSKCITLVISPLVSLMEDQVSGSSCSFFKIGCLHTGLTDRQRENVLENTKNGKLHA PHPAT1_665_PE34 NOISO IL----TGLTLVISPLVALMADQLQKLPP-LLPGGLINSSQTASESTEIMSKVISGHIKV PIG4_1_PE21 NOISO LYSRRSPCLTLVISPLMSLMDDQVSGLPP-GLKAACIHSGMSKKQRNSALQKARSAQVQV PIG4_1_PE7 NOISO LYSRRSPCLTLVISPLMSLMDDQVSGLPP-GLKAACIHSGMSKKQRNSALQKARSAQVQV PONPY8_159_PE8 NOISO LYTRRSPCLTLVVSPLLSLMDDQVSGLPP-CLKAACIHSGMTRKQRESVLQKVRAAQVHV POPTR_2_PE618 NOISO VF----SGVTLVVSPLVALMIDQLKQLPP-VIQGGLLCSSQTPQEVSETLRLLQEGGIKV PTEVAGS_3119_PE13 NOISO LYARRSPCLTLVISPLLSLMDDQVSGLPP-GLKAACVHSGMNRKQRNSALQKARAAQVHV RAT7_PE1328 ENSRNOG00000032446 LYAKRSPCLTLVVSPLLSLMDDQVSDLPS-CLKAACLHSGMTKKQRESVLKKVRAAQVHV RAT7_PE1329 ISOFORMIN LYAKRSPCLTLVVSPLLSLMDDQVSDLPS-CLKAACLHSGMTKKQRESVLKKVRAAQVHV SORARGS_5380_PE3 NOISO LYFQRSPCLTLVVSPLLSLMDDQXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX SORBI_7_PE1508 NOISO IL----PGLTLVVSPLLSLMVDQLRKLPA-FLPGGLLASNQTSDEFHETLQRLRGGEIKV SPETRGS_4687_PE12 NOISO LCARRSSCLTLVVSPLLSLMDDQMSSLPP-CLKAACLHSGMTKKQQESVLQKVQAAQXXX TARSYGS_5559_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXEQVQT TETNG21RD_PE128 ENSTNIG00000017539 MYAKRFKTITLVISPLVSLMDDQLSGLPA-SLKAACIHSNMTMKQREAAVEKVKSGQVCV TETNG21RD_PE129 ISOFORMIN MYAKRFKTITLVISPLVSLMDDQLSGLPA-SLKAACIHSNMTMKQREAAVEKVKSGQVCV TRIAD_1_PE1288 NOISO LYAARSECITLVISPLVSLMEDQVSKFPP-FLKGACLHSNLSQSQRKKVYKQLEDKKISV VITVI_1_PE1156 NOISO VL----PGITLVVSPLVALMIDQLKQLPP-MIPGGLLSSSQSAEETSETLRQLREGTIKV XENTR1850_PE1 NOISO MYAKRSRCITLVISPLVSLMDDQVSGLPP-KLKAVCIHSNMTRTQRETAIEKVKQGKVHV MATCH CONSENSUS ?????????TLV?SPL?SLM?DQ????P???L?????H?????????????????????V

ACYPI_11004_PE3 NOISO LLLSPEAVVSGFNT-----DWLLKLP-PIAFVCLDEAHCLSQWSHNFRPSYLMICQV--- AEDAE_4224_PE7 NOISO LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFRPSYLMICRV--- AILMEGL192891_1_1_PE17 NOISO LMLSPEALVGAGAGIPGRL---PQLP-PVAFACVDEAHCLSQWSHNFRPCYLRVCKV--- ANOCA1050_PE2 NOISO LLLSPEALVGGGLSGSSCLPPADQLP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- ANOGA_1_PE1398 AGAP005917 LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_2_PE1395 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_3_PE1398 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_4_PE1398 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_5_PE1397 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_6_PE1398 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_7_PE1397 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_8_PE1398 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ ANOGA_9_PE1398 HAPLOTYPE LLISPEAVVSGEKS-TGFGSLLRQLP-PIAFACIDEAHCVSQWSHNFQ------------ APIME_119_PE11 NOISO LLISPEAVVAGEKS-TGFGALLRELP-PIAFACIDEAHCISQWSHNFRPSYLMVCRV--- APIME_119_PE12 NOISO LLISPEAVVAGEKS-TGFGALLRELP-PIAFACIDEAHCISQWSHNFRPSYLMVCRV--- ARALY_1_PE2902 NOISO LFVSPERLLNVE-----FLSMFRMSL-SVPLVVVDEAHCVSEWSHNFRPSYMRLKAS--- ARATH_1_PE3672 NOISO LFVSPERLLNVE-----FLSMFRMSL-SVSLVVVDEAHCVSEWSHNFRPSYMRLKAS--- BOVIN14_1_PE17 ISOFORMIN LMLSPEALVGAGAS--TLL---SQLP-PVAFACLDEAHCLSQWSHNFRPCYLRVCQT--- BOVIN14_1_PE18 ENSBTAG00000010276 LMLSPEALVGAGAS--TLL---SQLP-PVAFACLDEAHCLSQWSHNFRPCYLRVCQT--- BOVIN14_1_PE19 ISOFORMIN LMLSPEALVGAGAS--TLL---SQLP-PVAFACLDEAHCLSQWSHNFRPCYLRVCQT--- BRADI_5_PE1289 NOISO LFVSPERFLNEE-----FLLIFRDTL-PISLVVIDEAHCISEWSHNFRPSYLRLRAS--- CALJA16_53_PE9 NOISO LLLTPEALVGAG-----GLPPATKLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCRV--- CANFA13_42_PE41 NOISO LVLSPETLVGAGAGMPGHL---PQLP-PVAFACIDEAHCISQWSHNFRPCYLRVCKV--- CAVPO95_4_PE36 NOISO LMLSPEALVRAGSGGPGGLLQAARLP-PVAFACIDEAHCLSTWSHNFRPCYLRICKV--- CIOIN3Q_5_PE89 NOISO LLVSPEALTSWAGMS-PYYSPLAKLP-PISFVCVDECHCLSEWSHSFRPSYLRVCKV--- CULQU_306_PE9 NOISO LLISPEAVVSGEKS-TGFGSLLKQLP-PIAFACIDEAHCVSQWSHNFRPSYLMICRV--- CULQU_602_PE10 NOISO LLISPEAVVSGEKS-TGFGSLLKQLP-PIAFACIDEAHCVSQWSHNFRPSYLMICRV--- DANRE19_4_PE9 NOISO LLLSPEALVGGGHSGSGCLPPADQLP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- DASNOGS_5448_PE2 NOISO LMLSPEALVGVGAGGPACLPRLGQLP-PVAFACIDEAXXXXXXXXXXXXXXXXXXXX--- DIPORGS_5063_PE4 NOISO LLLSPEALVGVGTRSPGALPQAAQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- DROME3L_9_PE65 NOISO LLVSPEAVVAGERA-TGFGAILRQLP-PIAFACIDEAHCVSQWSHNFRPSYLMICKV--- ECHTEGS_6465_PE2 NOISO LLLSPEAVVGAGSGGATCLPQASQLP-PVPFACID-AHCLSQWXXXXXXXXXXXXXXXXX ERIEUGS_6628_PE4 NOISO LLLSPEALVGAGDL--------PQLP-PIAFACLDEAHCLSQWSHNFRPCYLRVCKV--- FELCAGS_5236_PE10 NOISO LMLSPEALVGAGPLA---P---SQLP-PVAFACVDEAHCLSQWSHNFRPCYLRVCKV--- FUGRU37_1_PE108 ENSTRUG00000012749 LLLSPEALVGGGGSGSGCLPSAQELP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- FUGRU37_1_PE109 ISOFORMIN LLLSPEALVGGGGSGSGCLPSAQELP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- FUGRU37_1_PE110 ISOFORMIN LLLSPEALVGGGGSGSGCLPSAQELP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- GASACGROUPIII_7_PE38 NOISO LLLSPEALVGGGGSGSGCLPSAQELP-PVSFACIDEAHCVSEWSHNFRPCYLRLCKV--- GORGO8_151_PE6 NOISO LMLTPEALVGAG-----GLPPAAQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- HORSE9_86_PE8 NOISO LMLSPEALAGAGEGGPACL---TQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- HS8_PE3578 ISOFORMIN LMLTPEALVGAG-----GLPPAAQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- HS8_PE3579 ENSG00000160957 LMLTPEALVGAG-----GLPPAAQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- LOXAF185_PE18 NOISO LMLSPEALVEAGTGGPVCLPPASQLP-PVAFACIDEVHCLSQWSHNFRPCYLRVCKV--- MACEUGS_7560_PE2 NOISO LLLSPEAVVGAGAGGFSCLPPAARLP-PVAFACIDEAHCLSQWSHNFRPCYLRLCKV--- MACMU8_150_PE22 NOISO LMLTPEALVGAG-----GLSPATQLP-PVAFACIDEVHCLSQWSHNFRPCYLRVCRV--- MAIZE_2_PE7014 NOISO LFVSPERFLNEE-----FLLIFRDGL-QISLVAIDEAHCISEWSHNFRPSYLRLRAS--- MICMUGS_3858_PE24 NOISO LMLSPEALMGAG-----GPAILTQLP-PVAFACVDEAHCLSQWSHNFRPCYLRVCKM--- MICSR_3_PE377 NOISO LFVSPERLLNER-----FLSDLRCVPGGVSLAVVDEAHCVSEWSHNFRPAYHRLGRI--- MONDO3_446_PE28 ISOFORMIN LLLSPEAVVG--AGGFSCLPPAARLP-PVAFACIDEAHCLSQWSHNFRPCYLRLCKV--- MONDO3_446_PE29 ENSMODG00000011014 LLLSPEAVVG--AGGFSCLPPAARLP-PVAFACIDEAHCLSQWSHNFRPCYLRLCKV--- MOUSE15_PE705 ENSMUSG00000033762 LIVSPEALVGCGARGPGSLPQAAQLP-PIAFACIDEVHCLSQWSHNFRPCYLRVCKV--- MOUSE15_PE706 ISOFORMIN LIVSPEALVGCGARGPGSLPQAAQLP-PIAFACIDEVHCLSQWSHNFRPCYLRVCKV--- MYOLUGS_4426_PE2 NOISO LMLSPEALVGAGA---L---PATQLP-PVAFVCIDEAHCLSQWSHNFRPCYLRVCKV--- NEMVE_4617_PE16 NOISO LLVSPEALVGGGMGGSGCLPSSTKMP-PIAFACIDEAHCLSEWSHNFRPSYLRVCKI--- OCHPRGS_3806_PE4 NOISO LMLSPEALVGAG-----AIPLTTQLP-PVAFVCIDEAHCLSQWSHNFRPCYLHVCKV--- ORNANCONTIG341_PE6 ENSOANG00000003526 LLLSPEAV--------GCLPAAAQLP-PMAFACIDEAHCLSQWSHNFRPCYLRLCKV--- ORNANCONTIG341_PE7 ISOFORMIN ------------------------------FACIDEAHCLSQWSHNFRPCYLRLCKVRPR ORYSI_7_PE1798 NOISO LFVSPERFLNEE-----FLLIFRDTL-PISLVAIDEAHCISEWSHNFRPSYLRLRAS--- ORYSJ_7_PE4100 NOISO LFVSPERFLNEE-----FLLIFRDTL-PISLVAIDEAHCISEWSHNFRPSYLRLRAS--- OSTLU_4_PE413 NOISO LFVSPERLLNEH-----FVNDLQNVPGGVSLACIDEAHCVSEWSHNFRPAYHRLGRI--- OTOGAGS_5082_PE6 NOISO LMLSPEALMGSGG--PASLPHAVQLP-PVAFACVDEAHCISQWSHNFRPCYLRICKM--- PANTR8_151_PE26 NOISO LMLTPEALVGAG-----GLPPATQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- PEDHC_890_PE62 NOISO LLVSPEAIVSGDSS-KGFGSILKQLP-PIAFACIDEVHCISQWSHNFRPSYLMVNKV--- PHPAT1_665_PE34 NOISO LFISPERLFSET-----FLTAMDSLP-EISLAVVDEAHCLSEWSHNFRPSYYRLGK---- PIG4_1_PE21 NOISO LMLSPEALAGAGAAGLAFL---TQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- PIG4_1_PE7 NOISO LMLSPEALAGAGAAGLAFL---TQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- PONPY8_159_PE8 NOISO LMLTPEALVGAG-----GLPPAAQLP-PVAFACIDEAHCLSQWSHNFRPCYLRVCKV--- POPTR_2_PE618 NOISO LFVSPERFLNAE-----FLSILSP-I-PISLLVVDEAHCISEWSHNFRPSYMRLRAS--- PTEVAGS_3119_PE13 NOISO LMLSPEALVGAGA---GGPACLAQLP-PVAFACIDEAHCLSQWSHNFRPCYLRICKV--- RAT7_PE1328 ENSRNOG00000032446 LIVSPEALVGCGAKGPANLPPAAQLP-PVAFACIDEVHCLSQWSHNFRPCYLRVCKV--- RAT7_PE1329 ISOFORMIN LIVSPEALVGCGAKGPANLPPAAQLP-PVAFACIDEVHCLSQWSHNFRPCYLRVCKV--- SORARGS_5380_PE3 NOISO XXXXXXXXXXXX-----XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXV--- SORBI_7_PE1508 NOISO LFVSPERFLNEE-----FLLIFRDGL-PISLVAIDEAHCISEWSHNFRPSYLRLRAS--- SPETRGS_4687_PE12 NOISO XXXXXXXXXXXX------------------------XXXXXXXXXXXXXXWMDKGPV--- TARSYGS_5559_PE1 NOISO LLRSQEEVVGTEVWSLANIPQAAQLP-PVAFACIDEVHCLSQWSHNFRPCYLSVCKM--- TETNG21RD_PE128 ENSTNIG00000017539 LLLSPEALVGGGGSGSGCLPSAQELP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- TETNG21RD_PE129 ISOFORMIN LLLSPEALVGGGGSGSGCLPSAQELP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- TRIAD_1_PE1288 NOISO LLTSPETLVSALNDGERL---RTLLP-PVAFACIDEIHCVSEWSHHFRPCYLLLCKL--- VITVI_1_PE1156 NOISO LFVSPERFLNAE-----FLSIVSAGP-PISLVVVDEAHCVSEWSHNFRPSYMRLRAS--- XENTR1850_PE1 NOISO LLLSPEALVGGGQSGSSCLPPAEQLP-PVAFACIDEAHCVSEWSHNFRPCYLRLCKV--- MATCH CONSENSUS L??SPE??????????????????LP?P??FAC?DEAHC?S?WSHNFRP?Y?????????

ACYPI_11004_PE3 NOISO ----------------------LREKFGVKTFLGLTATATIS--------TVSSIASELM AEDAE_4224_PE7 NOISO ----------------------LKEKLGVQTILGLTATATVQ--------TRLSIVEHLA AILMEGL192891_1_1_PE17 NOISO ----------------------LREHMGVHCFLGLTATATRS--------TARDVAQHLG ANOCA1050_PE2 NOISO ----------------------LRERLGVRCFLGLTATATLS--------TARDVAHHLG ANOGA_1_PE1398 AGAP005917 -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_2_PE1395 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_3_PE1398 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_4_PE1398 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_5_PE1397 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_6_PE1398 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_7_PE1397 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_8_PE1398 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA ANOGA_9_PE1398 HAPLOTYPE -------------------------KLGVKTILGLTATATVICLIRLSSICRQSIVSHLA APIME_119_PE11 NOISO ----------------------LKEKLGVKTVLALTATARKA--------TAESIVNHLG APIME_119_PE12 NOISO ----------------------LKEKLGVKTVLALTATARKA--------TAESIVNHLG ARALY_1_PE2902 NOISO ---------------------MLFSELKAKCILAMTATATTM--------TLQAVMSALE ARATH_1_PE3672 NOISO ---------------------MLFSELKAECILAMTATATTM--------TLQAVMSSLE BOVIN14_1_PE17 ISOFORMIN ----------------------LRDQMGVHCFLGLTATATRS--------TALDVAWHLG BOVIN14_1_PE18 ENSBTAG00000010276 ----------------------LRDQMGVHCFLGLTATATRS--------TALDVAWHLG BOVIN14_1_PE19 ISOFORMIN ----------------------LRDQMGVHCFLGLTATATRS--------TALDVAWHLG BRADI_5_PE1289 NOISO ---------------------LLRRKLNIQCILAMTATATTQ--------TLQEIVNALE CALJA16_53_PE9 NOISO ----------------------LRERMGVHCFLGLTATATRR--------TASDVAQHLA CANFA13_42_PE41 NOISO ----------------------LREHMGVRCFLGLTATATRS--------TARDVARHLG CAVPO95_4_PE36 NOISO ----------------------LRERMGVHCFLGLTATATHS--------TARDVAHHLG CIOIN3Q_5_PE89 NOISO ----------------------LKDQLGIKCLVGLTATSTRS--------TCISVAKQLG CULQU_306_PE9 NOISO ----------------------LKEKLGVKTILGLTATATVQ--------TRVSIVEHLG CULQU_602_PE10 NOISO ----------------------LKEKLGVKTILGLTATATVQ--------TRVSIVEHLG DANRE19_4_PE9 NOISO ----------------------LRDRLGVRCLLGLTATATLS--------TALDIARHLD DASNOGS_5448_PE2 NOISO ----------------------XXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXX DIPORGS_5063_PE4 NOISO ----------------------LREQLGVRCFLGLTATATRG--------TARDVAWHLG DROME3L_9_PE65 NOISO ----------------------LRKNLGVRTVLGLTATATLP--------TRVSIINHLG ECHTEGS_6465_PE2 NOISO XXXXXXXXXX------------------XXXXXXXXXXXX-X--------XX-XXX-XXX ERIEUGS_6628_PE4 NOISO ----------------------LRERLGVRCFLGLTATATRS--------TARDVAHHLG FELCAGS_5236_PE10 NOISO ----------------------LREHMGVRCFLGLTATATHS--------TSRDMAQHLG FUGRU37_1_PE108 ENSTRUG00000012749 ----------------------LRERLGVQCFLGLTATATLS--------TALDIARHLD FUGRU37_1_PE109 ISOFORMIN ----------------------LRERLGVQCFLGLTATATLS--------TALDIARHLD FUGRU37_1_PE110 ISOFORMIN ----------------------LRERLGVQCFLGLTATATLS--------TALDIARHLD GASACGROUPIII_7_PE38 NOISO ----------------------LRERLGVQCLLGLTATATLS--------TAMDIARHLD GORGO8_151_PE6 NOISO ----------------------LRERMGVHCFLGLTATATRR--------TASDVAQHLA HORSE9_86_PE8 NOISO ----------------------LRERMGVHCFLGLTATATRS--------TARDVAWHLG HS8_PE3578 ISOFORMIN ----------------------LRERMGVHCFLGLTATATRR--------TASDVAQHLA HS8_PE3579 ENSG00000160957 ----------------------LRERMGVHCFLGLTATATRR--------TASDVAQHLA LOXAF185_PE18 NOISO ----------------------LREHMGVHCFLGLTATAPRS--------TALDVARHLG MACEUGS_7560_PE2 NOISO ----------------------LRERLGVRCFLGLTATATRT--------TARDVGQHLG MACMU8_150_PE22 NOISO ----------------------LRERMGVHCFLGLTATATRR--------TASDVAQHLA MAIZE_2_PE7014 NOISO ---------------------LLRRKLNVQSILAMTATATTQ--------TLEEIVTVLE MICMUGS_3858_PE24 NOISO ----------------------LREHIGVQCFLGLTATATRS--------TARDVAQHLG MICSR_3_PE377 NOISO ---------------------LQSRLQLQGPVLALSATATAR--------TERHLRSQLC MONDO3_446_PE28 ISOFORMIN ----------------------LRERLGVRCFLGLTATATCA--------TARDVGEHLG MONDO3_446_PE29 ENSMODG00000011014 ----------------------LRERLGVRCFLGLTATATCA--------TARDVGEHLG MOUSE15_PE705 ENSMUSG00000033762 ----------------------LREHMGVRCFLGLTATATRS--------TARDVAQHLG MOUSE15_PE706 ISOFORMIN ----------------------LREHMGVRCFLGLTATATRS--------TARDVAQHLG MYOLUGS_4426_PE2 NOISO ----------------------LRESLGVGCFLGLTATATRS--------TTLDVAEHLG NEMVE_4617_PE16 NOISO ----------------------LRDRYGVQCFLGLTATATQS--------TADSVAQHLG OCHPRGS_3806_PE4 NOISO ----------------------LRERVGVRCFLGLTATATRS--------TARDVARHLG ORNANCONTIG341_PE6 ENSOANG00000003526 ----------------------LRERLGVKCFLGLTATATRA--------TARDVAQHLG ORNANCONTIG341_PE7 ISOFORMIN AWGAVGRGSRRTRERAPPPSQVLRERLGVKCFLGLTATATRA--------TARDVAQHLG ORYSI_7_PE1798 NOISO ---------------------LLRRKLNVQCILAMTATATTQ--------TLEEIMNALE ORYSJ_7_PE4100 NOISO ---------------------LLRRKLNVQCILAMTATATTQ--------TLEEIMNALE OSTLU_4_PE413 NOISO ---------------------LNDRVQAQT-TLALTATATKK--------TEVSLIKQLG OTOGAGS_5082_PE6 NOISO ----------------------LREHLDVHCFLGLTATATHS--------TARDVAQHLG PANTR8_151_PE26 NOISO ----------------------LRERMGVHCFLGLTATATRR--------TASDVAQHLA PEDHC_890_PE62 NOISO ----------------------LREKFGIATVLGLTATATVS--------TIRSITRELK PHPAT1_665_PE34 NOISO ---------------------ILKQRLSVPCLLALTATATKD--------TECSITKALS PIG4_1_PE21 NOISO ----------------------LRERVGVSCFLGLTATATRS--------TALDVAQHLG PIG4_1_PE7 NOISO ----------------------LRERVGVSCFLGLTATATRS--------TALDVAQHLG PONPY8_159_PE8 NOISO ----------------------LRERMGVHCFLGLTATATHR--------TASDVAQHLA POPTR_2_PE618 NOISO ---------------------LLCTRLNIGCILAMTATATTT--------TLNAIMSALE PTEVAGS_3119_PE13 NOISO ----------------------LREHLGVCCFLGLTATATHS--------TALDVAQHLG RAT7_PE1328 ENSRNOG00000032446 ----------------------LREHMGVRCFLGLTATATRS--------TARDVAQHLG RAT7_PE1329 ISOFORMIN ----------------------LREHMGVRCFLGLTATATRS--------TARDVAQHLG SORARGS_5380_PE3 NOISO ----------------------LREQVGVHTFLGLTATATRS--------TTLDVAQHLG SORBI_7_PE1508 NOISO ---------------------LLRRKLNVQCILAMTATATTQ--------TLEEIVTALE SPETRGS_4687_PE12 NOISO ----------------------LREHMGVRCFLGLTATPTRS--------TARDVAQHLG TARSYGS_5559_PE1 NOISO ----------------------LRERKGVRCFLGITATATRS--------TVRVIAQHLG TETNG21RD_PE128 ENSTNIG00000017539 ----------------------LRDRLGVQCLLGLTATATLS--------TALDIARHLD TETNG21RD_PE129 ISOFORMIN ----------------------LRDRLGVQCLLGLTATATLS--------TALDIARHLD TRIAD_1_PE1288 NOISO ----------------------LKERLGVKCLLGLTATATVP--------TINSVCAHLG VITVI_1_PE1156 NOISO ---------------------LLHAVLNAKCILAMTATATSR--------TLHAVMHALE XENTR1850_PE1 NOISO ----------------------LRERLGVNCLLGLTATATRA--------TAEDVARHLG MATCH CONSENSUS ??????????????????????L????GV???LGLTATAT??????????T???????L?

ACYPI_11004_PE3 NOISO LDDDPNSIIKDTPLPDNLMLSVSRDKD------------RDKALINLLNGDRFKHCSSII AEDAE_4224_PE7 NOISO VPDGINGIISDIPLPDNLILTVSKDAN------------RDAALLNLLRSDRFTDLHSNI AILMEGL192891_1_1_PE17 NOISO VAEELVLRGP-VTIPTNLYLSVSMDRD------------PDQALVTLLQSDRFRALSSVI ANOCA1050_PE2 NOISO ISGGEGIAVRSAAVPPNLHLSVSTDRD------------KDQALLSLLQGERFGGLDSII ANOGA_1_PE1398 AGAP005917 IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_2_PE1395 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_3_PE1398 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_4_PE1398 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_5_PE1397 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_6_PE1398 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_7_PE1397 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_8_PE1398 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII ANOGA_9_PE1398 HAPLOTYPE IPDGVQGIISDIPLPDNLLLTVSRDAN------------RDVALVELLQSERFSSLQSII APIME_119_PE11 NOISO IQDGIAGIISDVPIPKNLLLTISKDEN------------RDQALIKLLQSERFQECNSII APIME_119_PE12 NOISO IQDGIAGIISDVPIPKNLLLTISKDEN------------RDQALIKLLQSERFQECNSII ARALY_1_PE2902 NOISO IPST--NLIQKSQLRDNFELSVSLSGANRQ---------LMKDLLILMESHPYKEIRSII ARATH_1_PE3672 NOISO IPST--NLIQKSQLRDNFELSVSLSGANR-----------MKDLLILMESPPYKEIRSII BOVIN14_1_PE17 ISOFORMIN VTEESVLRGP-ATIPDNLHLSVSSDRD------------PDQALVTLLRSDRFRALGSVI BOVIN14_1_PE18 ENSBTAG00000010276 VTEESVLRGP-ATIPDNLHLSVSSDRD------------PDQALVTLLRSDRFRALGSVI BOVIN14_1_PE19 ISOFORMIN VTEESVLRGP-ATIPDNLHLSVSSDRD------------PDQALVTLLRSDRFRALGSVI BRADI_5_PE1289 NOISO IPSG--NLIQTSQVRENLQLSISMSEN------------RLKDLMLLLKSPPFVDMRSII CALJA16_53_PE9 NOISO VAEEPGLHGP-APVPANLHLSVSMDRD------------TDQALLTLLQGKRFRNLDSII CANFA13_42_PE41 NOISO VAEELVLRGP-ATVPSNLHLSVSRDRD------------PDQALVTLLQSDRFRALSSVI CAVPO95_4_PE36 NOISO ITEELSPRKG-SVIPANLHLSVSMDRN------------PDQALVTLLQGDRFRSLDSVI CIOIN3Q_5_PE89 NOISO ITDPRHGMILSMSLPKNLSLSISKDRY------------KDEALEMLLNGDRFRKLDSVI CULQU_306_PE9 NOISO IPDGTNGIISDIPLPDNLNLTVSRDAN------------RDAALLHLLQSDRFADLRSII CULQU_602_PE10 NOISO IPDGTNGIISDIPLPDNLNLTVSRDAN------------RDAALLNLLQSERFADLRSII DANRE19_4_PE9 NOISO ISDEDGIAVRSAAVPHNLQLSVSMDRD------------KDQALVSLLKGERFGALDSVI DASNOGS_5448_PE2 NOISO XXXXXXXXXX-XXXXXXXXXXXXXXXX------------XXXXXXXXXXXXXXXXLDSVI DIPORGS_5063_PE4 NOISO VSEDLDLVGTSPTIPANLHLSVSMDRD------------PEQALVTLLQSDRFRSLDSVI DROME3L_9_PE65 NOISO ISDGERGIISDIPLPDNLVLSVSKDEN------------RDAALLQLLNSERFEPCQSII ECHTEGS_6465_PE2 NOISO XXXX--XXXX---XXXXXXXXXXXXXX------------XXXXXXXXXXXXXXXXXXXXX ERIEUGS_6628_PE4 NOISO IAEDPSLRES-AAIPSNLHLSVSMDRD------------PDQALVTLLQSDRFRTLNSVI FELCAGS_5236_PE10 NOISO VAEEHVLRGP-VTIPTNLYLSVSTDRN------------PDQALVTLLQSDRFRDLNSVI FUGRU37_1_PE108 ENSTRUG00000012749 IRNQDGIAVRSAAVPPNLHLSVSMDRE------------KDQALVSLLKGERFDCLDSVI FUGRU37_1_PE109 ISOFORMIN IRNQDGIAVRSAAVPPNLHLSVSMDRE------------KDQALVSLLKGERFDCLDSVI FUGRU37_1_PE110 ISOFORMIN IRNQDGIAVRSAAVPPNLHLSVSMDRE------------KDQALVSLLKGERFDCLDSVI GASACGROUPIII_7_PE38 NOISO ITDQDGIAVRSAAVPPNLQLSVSMDRE------------KDQALVSLLKGDRFGCLDSVI GORGO8_151_PE6 NOISO VAEGPDLHGP-APVPANLHLSVSMDRD------------TDQALLTLLQGKRFRNLDSII HORSE9_86_PE8 NOISO VAEEAVLRGP-VTIPANLHLSVSMDRD------------PDQALVTLLQSERFRALDSVI HS8_PE3578 ISOFORMIN VAEEPDLHGP-APVPTNLHLSVSMDRD------------TDQALLTLLQGKRFQNLDSII HS8_PE3579 ENSG00000160957 VAEEPDLHGP-APVPTNLHLSVSMDRD------------TDQALLTLLQGKRFQNLDSII LOXAF185_PE18 NOISO VTEGPSPSGLPATIPTNLHLSVSMDRD------------PEQALVTLLQGERFRSLDSAI MACEUGS_7560_PE2 NOISO IPEEAIFGVHLATIPPNLYLSVSLDRD------------KDQALVTLLKGERFGSLGSII MACMU8_150_PE22 NOISO VNEEPGLHGP-APVPANLHLSVSMDRD------------TDQALLTLLQGKRFRNLDSII MAIZE_2_PE7014 NOISO IPSD--NLIKTSQIRDNLQLFISMSNN------------RLKDLLLLLKASPFVDMKSII MICMUGS_3858_PE24 NOISO IMEELGPCGP-SPIPANLHLSVSMDRD------------PEQALVTLLQGDRFRALDSII MICSR_3_PE377 NOISO IPKE--GAYRNDTIRPNLTLAAMRVPAN----------SRDPTLFYMLTKEPEYSEGSVI MONDO3_446_PE28 ISOFORMIN IPEEAIFGTHLAAIPPNLHLSVSLDRD------------KDQALVSLLQGERFRDLSSII MONDO3_446_PE29 ENSMODG00000011014 IPEEAIFGTHLAAIPPNLHLSVSLDRD------------KDQALVSLLQGERFRDLSSII MOUSE15_PE705 ENSMUSG00000033762 IAGEFELSGS-ANIPANLHLSVSMDRD------------SDQALVTLLQGDRFRTLDSVI MOUSE15_PE706 ISOFORMIN IAGEFELSGS-ANIPANLHLSVSMDRD------------SDQALVTLLQGDRFRTLDSVI MYOLUGS_4426_PE2 NOISO IAKEGVLRGP-VTIPANLHLSVSMDRD------------PDQALVTLLRGDRFRTLDSVI NEMVE_4617_PE16 NOISO IADA-GAVIRGAAVPPNLRLSVSRDRD------------KDKALIELLQGPRFSRCESII OCHPRGS_3806_PE4 NOISO VADELGLREP-VAVPLNLHLSVSMDRE------------PEQALVTLLQGDRFRVLDSII ORNANCONTIG341_PE6 ENSOANG00000003526 THEGVDLGVHLAAIPPNLHLSVSLDRD------------KDQALVTLLKGERFRSLGSII ORNANCONTIG341_PE7 ISOFORMIN THEGVDLGVHLAAIPPNLHLSVSLDRD------------KDQALVTLLKGERFRSLGSII ORYSI_7_PE1798 NOISO IPSD--NLIQTSQIRENLQLSISTSDN------------RLKDLMLLLKSPPFVDMRSII ORYSJ_7_PE4100 NOISO IPSD--NLIQTSQIRENLQLSISTSDN------------RLKDLMLLLKSPPFVDMRSII OSTLU_4_PE413 NOISO IPSE--GVMRNVRVRDNLILSVMRVPDV----------ARERTLCHMLKHDELLQEGSII OTOGAGS_5082_PE6 NOISO VVGELSLLGP-APIPANLNLSVSIDKD------------PDKALVTLLQGDRFRTLDSII PANTR8_151_PE26 NOISO VAEEPDLHGP-APVPTNLHLSVSMDRD------------TDQALLTLLQGKRFRNLDSII PEDHC_890_PE62 NOISO IESEKGVIKD-IPIPDNILLSVSVDDD------------KDEALIKLLTSEKFQDFNSIL PHPAT1_665_PE34 NOISO IPSS--GILEASCVRHNLRLSVSRSSHRQVTSQ-----ALHYDLLLLLQSIPFSDIKSII PIG4_1_PE21 NOISO VAEESVLRGQ-GTIPANLHLSVSMDRD------------PDQALVTLLQSDRFCALDSII PIG4_1_PE7 NOISO VAEESVLRGQ-GTIPANLHLSVSMDRD------------PDQALVTLLQSDRFCALDSII PONPY8_159_PE8 NOISO VAEEPGLHRP-APVPANLHLSVSMDRD------------TDQALLTLLRGERFRDLDSII POPTR_2_PE618 NOISO IPST--NLIQNAKLRDNMQLSVSLSGNRQLTYHHYLEFNRTKDLLTLIKSPPFVELQSII PTEVAGS_3119_PE13 NOISO VAKEHVLRGP-VIIPPNLYLSVSMDRD------------PDQALVTLLQSDRFRSLDSVI RAT7_PE1328 ENSRNOG00000032446 IAEELEVSGS-ASIPANLHLSVSMDRD------------SDQALVTLLQGDRFRTLDSII RAT7_PE1329 ISOFORMIN IAEELEVSGS-ASIPANLHLSVSMDRD------------SDQALVTLLQGDRFRTLDSII SORARGS_5380_PE3 NOISO VAGP--GQGP-TAIPSNLQLSVSMDRD------------PDQALVTLLQSDRFRALDSVI SORBI_7_PE1508 NOISO IPSD--NLIKTSQIRDNLQLSISTSNN------------RLKDLLLLLKSSPFVDMKSII SPETRGS_4687_PE12 NOISO VAEE--LQGP-APIPANLHLSVSVDRN------------PHQALVTLLQGDRFRALDSII TARSYGS_5559_PE1 NOISO VAEEVGMRGP-APIPANLHLSVSMDRD------------TDQALVTLLQGDRFRTLDSVI TETNG21RD_PE128 ENSTNIG00000017539 INDQDGIAVRSAAVPPNLHLSVSTDRE------------KDQALVSLLKGERFGCLDSII TETNG21RD_PE129 ISOFORMIN INDQDGIAVRSAAVPPNLHLSVSTDRE------------KDQALVSLLKGERFGCLDSII TRIAD_1_PE1288 NOISO IANSDDGVIQGITLPENLHISVSCDDR------------KDNALVTLLNGNRFLFKNSII VITVI_1_PE1156 NOISO IPAA--NLIQKAQLRDNLQLSVSLSKNR--------------------QSPPFIEVQSII XENTR1850_PE1 NOISO VSQEGGIPVRMASVPPNLHLSVSMDRN------------RDQALVTLLKGERFGCLDSVI MATCH CONSENSUS ??????????????P?NL?L?VS?D?????????????????AL??LL???RF????S?I

ACYPI_11004_PE3 NOISO VYCIRREECERIASFIRTTFQVISQHTSN-----------------------GKRGQLSQ AEDAE_4224_PE7 NOISO VYCTRRDECERIASFLRTCFQDAQRAAESEA--------------SASAPTSRKRKKLNY AILMEGL192891_1_1_PE17 NOISO VYCNRREDTERVAALLRTCLREARDLGRR-------------------------GQAPKA ANOCA1050_PE2 NOISO IYCTRREETARIAALIRTCLQGRAVPLRK-------------------------GRNPKW ANOGA_1_PE1398 AGAP005917 VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_2_PE1395 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_3_PE1398 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_4_PE1398 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_5_PE1397 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_6_PE1398 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_7_PE1397 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_8_PE1398 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY ANOGA_9_PE1398 HAPLOTYPE VYCTRRDDCERVATFIRTCFQDAARAAAA--------------------ANAHKRKRLNY APIME_119_PE11 NOISO IYCTRREECVRIAGFLRISLQNVNNPEK-------------------------PNNKISF APIME_119_PE12 NOISO IYCTRREECVRIAGFLRISLQNVNNPEK-------------------------PNNKISF ARALY_1_PE2902 NOISO VYCKFQYETDMISKYLRD----------N-----------------------------NI ARATH_1_PE3672 NOISO VYCKFQYETDMISKYLRD----------N-----------------------------NI BOVIN14_1_PE17 ISOFORMIN IYCHRREDTERVAALLRTCLCDAQDPGPH-------------------------GRALEA BOVIN14_1_PE18 ENSBTAG00000010276 IYCHRREDTERVAALLRTCLCDAQDPGPH-------------------------GRALEA BOVIN14_1_PE19 ISOFORMIN IYCHRREDTERVAALLRTCLCDAQDPGPH-------------------------GRALEA BRADI_5_PE1289 NOISO VYCKFQSETDYVCKHLCD----------N-----------------------------NI CALJA16_53_PE9 NOISO IYCNRREDTERVAALLRTCLHPAQGPGPK-------------------------GRAPKT CANFA13_42_PE41 NOISO VYCHRRGDTERVAALLRTCLREAWDLRPG-------------------------GEVSRT CAVPO95_4_PE36 NOISO VYCNRREDTLRVAALLRTCLPTVQDPKAR-------------------------GRVPRA CIOIN3Q_5_PE89 NOISO IYCTRRDEVARVSSYLRTRMQREPTEAEPEP-EEQIVESNSKKRKRSTKPKSSKKRAVTI CULQU_306_PE9 NOISO VYCTRRDECERISGFLRTCFQDAQRESEAKE--------------G---AASKKRKRVNY CULQU_602_PE10 NOISO VYCTRRDECERISGFLRTCFQDAQRESEAKE--------------G---AASKKRKRVNY DANRE19_4_PE9 NOISO VYCTRREETSRIAALLRTCLQGVMLRESSKHTALQEDDDNPVGKKKKALARKKIRKPLKW DASNOGS_5448_PE2 NOISO IYCNRREDTERVAALLRTCLPS----GSG-------------------------GGAREA DIPORGS_5063_PE4 NOISO VYCNRRETTERVAALLRTCLCVERGPGPR-------------------------GQAPEA DROME3L_9_PE65 NOISO IYCTRRDECERIAGFIRTCVQDRREPTQ---------------------DQTKKRKRVNW ECHTEGS_6465_PE2 NOISO XXXXRREDTERTAARLRTALQES--PRPR-------------------------GVGTEK ERIEUGS_6628_PE4 NOISO VYCNRREDTERVAALLRTCLRGDRGPGSR-------------------------G---EA FELCAGS_5236_PE10 NOISO VYCNRREDTERIAALLRTCLCEAWDLGPR-------------------------GQAPEA FUGRU37_1_PE108 ENSTRUG00000012749 VYCTRREETVRVAALLRTCLQGVLVKENKQ-IKGGQDQNNPVGRKKKELARKKIRKPLKW FUGRU37_1_PE109 ISOFORMIN VYCTRREETVRVAALLRTCLQGVLVKENK----------------------KKIRKPLKW FUGRU37_1_PE110 ISOFORMIN VYCTRREETVRVAALLRTCLQGVLL------------------------ARKKIRKPLKW GASACGROUPIII_7_PE38 NOISO VYCTRRQETTRVAALLRTCLNGVLVKENKETNSGGQTLHNPLGQRKKDLARKKIRKPLKW GORGO8_151_PE6 NOISO IYCNRREDTERIAALLRTCLHAARVPGSG-------------------------GHAPKT HORSE9_86_PE8 NOISO VYCNRREDTERVAALLRTCLREAWAPGPG-------------------------GRAPEA HS8_PE3578 ISOFORMIN IYCNRREDTERIAALLRTCLHAAWVPGSG-------------------------GRAPKT HS8_PE3579 ENSG00000160957 IYCNRREDTERIAALLRTCLHAAWVPGSG-------------------------GRAPKT LOXAF185_PE18 NOISO VYCNRREDTERVAALLRTCLHK--TPGPR-------------------------GGVPEA MACEUGS_7560_PE2 NOISO VYCNRRDETVRVAALLRTCLQESQIPGPR-------------------------GQLPEA MACMU8_150_PE22 NOISO IYCNRREDTERIAALLRTCLHAAQGPGPG-------------------------GRAPKT MAIZE_2_PE7014 NOISO VYCKFQGETDYVSKYLCD----------N-----------------------------NI MICMUGS_3858_PE24 NOISO VYCNRREDTERVAALLRTCLCAVRGPAPG-------------------------DHAPEA MICSR_3_PE377 NOISO VYTAFQNQAETVAAYLQT----------K-----------------------------GV MONDO3_446_PE28 ISOFORMIN VYCNRRDETVRVAALIRTCLQDFPVPF-A-------------------------GRLPEA MONDO3_446_PE29 ENSMODG00000011014 VYCNRRDETVRVAALIRTCLQDFPVPF-A-------------------------GRLPEA MOUSE15_PE705 ENSMUSG00000033762 IYCTRRKDTERVAALLRTCLSMVGDSRPR-------------------------GCGPEA MOUSE15_PE706 ISOFORMIN IYCTRRKDTERVAALLRTCLSMVGDSRPR-------------------------GCGPEA MYOLUGS_4426_PE2 NOISO VYCNRREDTERVAALLRTCLPEARAPGPG-------------------------GQAPEA NEMVE_4617_PE16 NOISO IYCTRREVTERVATLIRTCMQHMQPTIRHDDV------------------------ISGS OCHPRGS_3806_PE4 NOISO VYCPRREDTERLAALLRTCLRDT--PEAR-------------------------GRDPEA ORNANCONTIG341_PE6 ENSOANG00000003526 VYCNRREETVRVAALIRTCLQGTPGP-PE-------------------------GRGQEA ORNANCONTIG341_PE7 ISOFORMIN VYCNRREETVRVAALIRTCLQGTPGP-PE-------------------------GNAREA ORYSI_7_PE1798 NOISO VYCKFQAETDFVSKYLCD----------N-----------------------------NI ORYSJ_7_PE4100 NOISO VYCKFQAETDFVSKYLCD----------N-----------------------------NI OSTLU_4_PE413 NOISO VYTATQRDSERVASYLYN----------E-----------------------------GI OTOGAGS_5082_PE6 NOISO VYCNRREDTERVAALLRTCLCAVQGLGFG-------------------------GCAPEA PANTR8_151_PE26 NOISO IYCNRREDTERIAALLRTCLHADWVPGSG-------------------------GRAPKT PEDHC_890_PE62 NOISO IYCTRRDDCERLATYIRTVMQNFFDCNET---------------------HKKKNRKLSW PHPAT1_665_PE34 NOISO IYCTYQAEADDISRYLEE----------N-----------------------------KI PIG4_1_PE21 NOISO IYCNRREDTERVAALLRTCLRETWALGPG-------------------------GWAPEA PIG4_1_PE7 NOISO IYCNRREDTERVAALLRTCLRETWALGPG-------------------------GWAPEA PONPY8_159_PE8 NOISO IYCNRREDTERIAALLRTCLHAARVPGSG-------------------------GRAPKT POPTR_2_PE618 NOISO IYCKFQSETDIISRYLCD----------N-----------------------------NI PTEVAGS_3119_PE13 NOISO IYCNRREDTERVSALLRTCLREAWAPGPR-------------------------GRVLEA RAT7_PE1328 ENSRNOG00000032446 IYCARRKDTERVAALLRTCLSTVRDSKPR-------------------------GRGPET RAT7_PE1329 ISOFORMIN IYCARRKDTERVAALLRTCLSTVRDSKPR-------------------------GRGPET SORARGS_5380_PE3 NOISO VYCNRREDTERVAALLRTCLHGARR--PG-------------------------GQAPET SORBI_7_PE1508 NOISO VYCKFQGETDYVSKYLCD----------N-----------------------------NI SPETRGS_4687_PE12 NOISO IYCNRREDTERVAALLRTCLYAGQDPGSR-------------------------GHAPET TARSYGS_5559_PE1 NOISO VYCNRRVDTERVAALLRTCLCATQGQEPG-------------------------GHAPKT TETNG21RD_PE128 ENSTNIG00000017539 VYCTRREETVRVAALLRTCLQGVFVKENKQ-TGSSQEHNNPVGQRKKDLARKKIRKPLKW TETNG21RD_PE129 ISOFORMIN VYCTRREETVRVAALLRTCLQGVFVKENKQ-TGSSQEHNNPVGQRKKDLARKKIRKPLKW TRIAD_1_PE1288 NOISO IYCTRRDETERIAQLIRSYLLRQTFEGMSNVTEVTY-----------TL---SREVDLEH VITVI_1_PE1156 NOISO IYCKFQSETDSISKYLCD----------N-----------------------------NI XENTR1850_PE1 NOISO VYCTRREETQRISALLRTSLQGVTVSNL----NSQEQEEATVSDRKKAQALKKIRRPLKW MATCH : . : CONSENSUS ?YC?RR????R?A???RT??????????????????????????????????????????

ACYPI_11004_PE3 NOISO IAEPYHAGLTAAKRKRTQKYFMDGQLKIVVATVAFGMGINKADLQGIIHYNMAKSLESYV AEDAE_4224_PE7 NOISO FAEPYHAGLSSARRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV AILMEGL192891_1_1_PE17 NOISO VAEAYHAGMCSRERRRVQQAFMDGRLRVVVATVAFGMGLDRPDVRAVLHLGLPASFESYV ANOCA1050_PE2 NOISO IADAYHAGLSSAERRRVQNNFMSGQLRVVAATVAFGMGLDKSDVRGVIHYNMPKNFESYV ANOGA_1_PE1398 AGAP005917 VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_2_PE1395 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_3_PE1398 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_4_PE1398 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_5_PE1397 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_6_PE1398 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_7_PE1397 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_8_PE1398 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV ANOGA_9_PE1398 HAPLOTYPE VAEPYHAGMPASRRRTIQNAFMSGELRIVVATIAFGMGINKADIRAIIHYNMPKNFESYV APIME_119_PE11 NOISO IAEAYHAGLSAHRRKIVQKAFMNGQTRIVVATVAFGMGINKPDIRAVIHYNMPGSFENYI APIME_119_PE12 NOISO IAEAYHAGLSAHRRKIVQKAFMNGQTRIVVATVAFGMGINKPDIRAVIHYNMPGSFENY