Alignment of the gene Family HOG000265824 of HOGENOM

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Isoforms are OFF
ACYPI_16299_PE4 NOISO -------------------------MS---------D-S---------SNSS-------- AEDAE_2225_PE16 AAEL008084 -----------------------MSLN---------E-G---------EVKL-------- AEDAE_4634_PE10 NOISO -----------------------MSLN---------E-G---------EVKL-------- AILMEGL192595_1_1_PE1 NOISO ---------------------------------------------------M-------- ALLMA_1_6023 NOISO -MP------PSDSTGAA-IDTADASTTR-----PSATSDTPAPVAGQKRPSPSPAPEDGS ALLMA_1_9354 NOISO -MP------PSGSTGAA-VDSADGSTPR-----PQAAGDTLAPVAGQKRPSPSPAPEDGS ANOCA19_6_PE11 NOISO ---------------------------------------------------M-------- ANOGA_172_PE170 NOISO --------------------------M---------A-E---------PVKL-------- APIME_303_PE18 NOISO -------------------------MM---------D-----------ELKL-------- BOVIN19_58_PE7 NOISO ---------------------------------------------------M-------- CABRI1_4_PE2016 NOISO -----------------------MSLG---------K-D---------RYS--------- CAEELIV_PE1070 F29B9.4 -----------------------MSLG---------R-D---------RYS--------- CALJA5_131_PE30 ENSCJAG00000013442 ---------------------------------------------------M-------- CANFA9_8_PE5 NOISO ---------------------------------------------------M-------- CAOWC1_1_8400 NOISO -------------------------MS---------E-K---------RVEL-------- CAVPO76_3_PE4 NOISO ---------------------------------------------------M-------- CHICK18_PE111 NOISO ---------------------------------------------------M-------- CHLRE_PE10084 NOISO ------------------------------------------------------------ CHOHOGS_636_PE1 NOISO ---------------------------------------------------M-------- CIOIN3P_2_PE37 NOISO --------------------------------------------------MS-------- CIOSAREFTIG_1_3_PE57 NOISO --------------------------------------------------MS-------- CULQU_1077_PE2 NOISO -----------------------MSSE---------A-G---------EVKL-------- DANRE3_63_PE21 ENSDARG00000034358 ---------------------------------------------------M-------- DASNOGS_542_PE1 NOISO ---------------------------------------------------M-------- DIPORGS_524_PE1 NOISO ---------------------------------------------------M-------- DROME3R_19_PE82 NOISO --------------------------M---------S-E---------EFKL-------- ECHTE281550_PE1 NOISO ------------------------------------------------------------ ECHTEGS_620_PE1 NOISO ---------------------------------------------------M-------- ECTSI_12_PE336 NOISO -----------------------------------------MVYRGDNGNQTSSWQ---S ERIEUGS_670_PE1 NOISO ---------------------------------------------------M-------- FELCAGS_359_PE3 NOISO ---------------------------------------------------M-------- FUGRU519_PE27 NOISO ---------------------------------------------------M-------- GASACGROUPXI_17_PE70 NOISO ---------------------------------------------------M-------- GORGO5_7_PE10 NOISO ---------------------------------------------------M-------- HORSE11_6_PE5 NOISO ---------------------------------------------------M-------- HS17_PE3079 ENSG00000070495 ---------------------------------------------------M-------- LOXAF49_6_PE7 NOISO ------------------------------------------------------------ MACEUGS_795_PE1 NOISO ---------------------------------------------------M-------- MACMU16_76_PE14 NOISO ---------------------------------------------------M-------- MICMUGS_352_PE3 NOISO ------------------------------------------------------------ MICSR_1_PE830 NOISO ------------------------------------------------------------ MONDO2_250_PE9 ENSMODG00000001566 ---------------------------------------------------M-------- MOUSE11_PE4108 ENSMUSG00000056962 ---------------------------------------------------M-------- MYOLUGS_462_PE2 NOISO ---------------------------------------------------M-------- NEMVE_8927_PE28 NOISO ---------------------------------------------------M-------- OCHPRGS_360_PE1 NOISO ------------------------------------------------------------ ORNANULTRA430_PE7 NOISO ------------------------------------------------------------ ORYLA1014_PE2 NOISO ---------------------------------------------------M-------- OSTLU_12_PE171 NOISO -----------------------MRNV-------DRECGTTA----ERRGKY-------- PANTR17_81_PE17 ENSPTRG00000009690 ---------------------------------------------------M-------- PEDHC_835_PE20 NOISO ---------------------------------------------------M-------- PHATR_4_PE173 NOISO ------------------------------------------------------------ PHINF1_2557_PE80 NOISO AMQSKKKLRRSPSLTSSSSDSSDSSSSSSS------SSSDSDAYTTSSVPRFPPVP---A PHSOJ1_1449_PE121 NOISO AMHSKKKFRRSPSVTSSSSDSSDSSSSSSSSSSSSSDGEDSDVCTTSKGPRFPPVP---A PHYRM_347_PE4 NOISO ------------------------------------------------------------ POEGU18_8_PE14 NOISO ---------------------------------------------------M-------- PONPY17_70_PE10 NOISO ---------------------------------------------------M-------- PROCAGS_604_PE1 NOISO ---------------------------------------------------M-------- RABITUN0145_PE3 NOISO ------------------------------------------------------------ RAT10_PE2538 ENSRNOG00000000250 ---------------------------------------------------M-------- SPETRGS_5110_PE2 NOISO ------------------------------------------------------------ SPIPN_1_5937 NOISO -----------------------MTAS---------ADE---------RLKYL--P--TK STRPU_20779_PE1 NOISO ------------------------------------------------------------ TARSYGS_644_PE1 NOISO ------------------------------------------------------------ TETNG3_PE1108 NOISO ---------------------------------------------------M-------- THTRA1_1_11407 NOISO -MIG-----WSSWLGGSWLVLAAMLAV---------VAVVVV------VVVFVAVA--VE THTRA1_1_8501 NOISO ------------------------------------------------------------ TRIAD_1_PE435 NOISO ---------------------------------------------------M-------- TUPGBGS_5346_PE2 NOISO ---------------------------------------------------M-------- TURTRGS_3026_PE2 NOISO ---------------------------------------------------M-------- XENTR178_2_PE28 NOISO ---------------------------------------------------M-------- MATCH CONSENSUS ???????????????????????????????????????????????????M????????

ACYPI_16299_PE4 NOISO ------ESRTRKRIQEAKNK--ARPGIEMSDKHAWHAHGYADNFKP---FTK-------- AEDAE_2225_PE16 AAEL008084 ------SHRTRKRVREVKRK--ARP--ELADKSAWVQLEYHRKFDK---FRE-------- AEDAE_4634_PE10 NOISO ------SHRTRKRVREVKRK--ARP--ELADKSAWVQLEYHRKFDK---FRE-------- AILMEGL192595_1_1_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLN--PAA-------- ALLMA_1_6023 NOISO KPAPPSDRKFLKRIIKTKAR--ARS--ELDPSVGWSSRRYQHRSLWH------------R ALLMA_1_9354 NOISO KPAQPSDRKFLKRIAKTKVR--ARS--ELDPSVGWSSRRYQHRSLWH------------R ANOCA19_6_PE11 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYCESFPLS--PAT-------- ANOGA_172_PE170 NOISO ------SHRTRKRVREVKRK--ARP--------AWVQLGYHQTFET---FSK-------- APIME_303_PE18 NOISO ------DHRAKKRIKEVKRK--ARP--ELGDKAAWIQHGYSKKFES---FWN-------- BOVIN19_58_PE7 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYFESFPLN--PAA-------- CABRI1_4_PE2016 NOISO ------LPRSYKRVSHAKEK--ARP--ELR-KFGWDTLGYAESFNPP------------P CAEELIV_PE1070 F29B9.4 ------LPRTYKRVSHAKDK--ARP--ELR-KFGWETLGYSESFNLP------------P CALJA5_131_PE30 ENSCJAG00000013442 ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- CANFA9_8_PE5 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLN--PAA-------- CAOWC1_1_8400 NOISO ------EEKVKRRIRRAKNR--GRS--ELKQDGGWTKYGYAQPGVLSLAPEP------TI CAVPO76_3_PE4 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFPLN--PAA-------- CHICK18_PE111 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYCETFPLS--PAA-------- CHLRE_PE10084 NOISO -----------------------------------TKHGYARSDLCS----T------EG CHOHOGS_636_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLN--PAA-------- CIOIN3P_2_PE37 NOISO ------NHKSRKRIRAAKKA--ARP--ELKGEEGWSGLKYQQWFDVS--FST-------- CIOSAREFTIG_1_3_PE57 NOISO ------DHKSRKRIRAAKKA--ARP--ELKGEDGWRGHKYQEWFDTS--ISA-------- CULQU_1077_PE2 NOISO ------SHRTRKRVREVKRK--ARP--ELADKVAWMQLEYYRKFDK---FRE-------- DANRE3_63_PE21 ENSDARG00000034358 ------NHKSKKRIKEAKRS--ARP--ELKDSSDWTKHEYCKSFDLS--HRS-------- DASNOGS_542_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLN--PAA-------- DIPORGS_524_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFPLS--PAA-------- DROME3R_19_PE82 NOISO ------PKRSRKRTREVKRK--ARP--ELDGENAWSAMRYCEKFEPF-----------WD ECHTE281550_PE1 NOISO -----MKHKSRKRTQGAKGS--V--WLELKDVLGWTGHNCYKSFLLNA----------EA ECHTEGS_620_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDALDWTRHNYYESFSLN--PAA-------- ECTSI_12_PE336 NOISO SSSPPRLERWERRIGDAKKS--HRPRL-----RDWGRDRFGVEG-CRAAAAFEELRDERD ERIEUGS_670_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- FELCAGS_359_PE3 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLN--QAA-------- FUGRU519_PE27 NOISO ------NHKSKKRIKEAKRS--ARP--ELKDSLDWIKHGYHDNFDLS--PRS-------- GASACGROUPXI_17_PE70 NOISO ------NHKSKKRIKEARRS--ARP--ELKDSLDWIKHDYHGSFDVS--HRT-------- GORGO5_7_PE10 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- HORSE11_6_PE5 NOISO ------NHKSKKRIREAKRRV-CRG--KLKTPLAGASPNQFGGCCRN--PAR-------- HS17_PE3079 ENSG00000070495 ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- LOXAF49_6_PE7 NOISO ---------------------------------------------MN--PAA-------- MACEUGS_795_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYFESFSLN--PAA-------- MACMU16_76_PE14 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- MICMUGS_352_PE3 NOISO ------------------------------------------------------------ MICSR_1_PE830 NOISO --------RCEKKIRAAKRA--TRSELSV-SGGEWQKHGYAYDPKVLS-ADG------L- MONDO2_250_PE9 ENSMODG00000001566 ------NHKSKKRIPEAKRN--ARP--ELKDSLDWTRHNYFESFSLN--PAF------TL MOUSE11_PE4108 ENSMUSG00000056962 ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESYPLN--PAA-------- MYOLUGS_462_PE2 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLN--PAA-------- NEMVE_8927_PE28 NOISO ------DSKTERRILAVKRK--ARP--ELKDEDAWTKMNCLKNFDAC--LTS-------- OCHPRGS_360_PE1 NOISO ------------------------------------------------------------ ORNANULTRA430_PE7 NOISO ------------------------------------------------------------ ORYLA1014_PE2 NOISO ------NHKSKKRIKEAKRS--ARP--ELKDSLDWIKHGYHESFDLS--HRT-------- OSTLU_12_PE171 NOISO RSSETHEEHVNKKIHAAKRR--TRSELSV-RQGGWAKHGYAYEDADAT-SRS------LK PANTR17_81_PE17 ENSPTRG00000009690 ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- PEDHC_835_PE20 NOISO ------EHRTRKRIREVKKKQDQVT--ELCEKGSWESLQIFKKFNEF-----------TN PHATR_4_PE173 NOISO ------------------------------------------------------------ PHINF1_2557_PE80 NOISO PVYPPK---VERVLHSAKKK--HRSDI---DPEAWNREGFAGSDVCDL---------PLD PHSOJ1_1449_PE121 NOISO PVYPPK---VERAVYSAKKK--HRSDI---DPEAWNREGFAGSNVCDL---------PLD PHYRM_347_PE4 NOISO -----------------------------------------------------------D POEGU18_8_PE14 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYCETFPLS--PTA-------- PONPY17_70_PE10 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- PROCAGS_604_PE1 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFPLS--PAA-------- RABITUN0145_PE3 NOISO -----------------------------KNSLDWTRHNYYESFPLN--PGE-------- RAT10_PE2538 ENSRNOG00000000250 ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESYPLS--PAA-------- SPETRGS_5110_PE2 NOISO ------------------------------------------------------------ SPIPN_1_5937 NOISO ----IKKHRYERKLAKAKAA--ARS--E-LDSFGWSKHCFSTRSFLV------------C STRPU_20779_PE1 NOISO ------------------------------------------------------------ TARSYGS_644_PE1 NOISO ------------------------------------------------------------ TETNG3_PE1108 NOISO ------NHKSKKRIKEAKRS--ARP--ELKDSLDWIKHGYHDHFDLS--PRS-------- THTRA1_1_11407 NOISO VEQAESREDFELRVRKIKKR--VNPDV---SSRKWGVKRHADVPEEVL-RGS------GE THTRA1_1_8501 NOISO ---------------------MCLPLWLYFEEDDWSKHGYAKLDILAT-FG--------T TRIAD_1_PE435 NOISO ------DKRTRKRIRQAKKK--ARP--ELKGSYGWKKFNYAKTMDLS--LNS-------- TUPGBGS_5346_PE2 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWTRHNYYESFSLS--PAA-------- TURTRGS_3026_PE2 NOISO ------NHKSKKRIREAKRS--ARP--ELKDSLDWIRHNYYESFSLN--PAA-------- XENTR178_2_PE28 NOISO ------NHKSKKRIKEAKRS--ARP--ELKDSQDWCRHNYCELYSLN--PSV-------- MATCH CONSENSUS ???????HKSKKRIREAKR???ARP??ELKDS?DW??H?Y???F?L??????????????

ACYPI_16299_PE4 NOISO VHDNVDRIDVEIVSPE-EFVEKYERPYKPVVIRGLQN---------NWRAS-----YKWT AEDAE_2225_PE16 AAEL008084 FEDNVERIHVKDVSPR-EFIERFESIYKPVVIEGITE---------GWKAE-----YKWT AEDAE_4634_PE10 NOISO FEDNVERIHVKDVSPR-EFIERFESIYKPVVIEGITE---------GWKAE-----YKWT AILMEGL192595_1_1_PE1 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT ALLMA_1_6023 NOISO IIDTVPRADVEGLSVR-DFVAQYEIPSKPVVLTGVTK---------DWSAN-----ANWQ ALLMA_1_9354 NOISO IIDTVPRVDVEDLSVR-DFVAQYEVPSKPVVLTGVTK---------DWSAN-----ANWQ ANOCA19_6_PE11 NOISO CKDNVERADALHLSLE-EFIERYEKPYKPVVLLNAQV---------GWPAQ-----EKWT ANOGA_172_PE170 NOISO FEDNVERIHVDKVSAR-EFIERFERIYQPVVIEGMQD---------GWRAG-----HKWT APIME_303_PE18 NOISO FTDNVDRIDESKVSTE-EFIEKYEKPYKPVIIQGVQN---------GWKAQ-----YKWT BOVIN19_58_PE7 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT CABRI1_4_PE2016 NOISO LKDTIPRVDGKKISVD-EFRRDFERPRIPVILTGLTD---------DWNAH-----EKWT CAEELIV_PE1070 F29B9.4 FRDSIQRVDGNNLTVE-EFRRDFERPRIPVIITGLTD---------NWAAK-----DKWT CALJA5_131_PE30 ENSCJAG00000013442 VADNVERADALQLSVE-EFVERYEKPYKPVVLLNAQE---------GWSAQ-----EKWT CANFA9_8_PE5 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT CAOWC1_1_8400 NOISO AKDTIERVHVDSLSEA-EFIERYERPGVPVVITGCAD---------DWPAT-----KNWT CAVPO76_3_PE4 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT CHICK18_PE111 NOISO CKDNMERADALQLTVE-EFVERYEKPYKPVVLLNAQV---------GWSAQ-----EKWT CHLRE_PE10084 NOISO LVDRIPRIHWKDLSVA-EFVERFERPRIPVVITGLAE---------HWPAT-----RRWT CHOHOGS_636_PE1 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT CIOIN3P_2_PE37 NOISO VRDNVERVDVGKLSCAD-FIEQYEKPNIPVVLLNTQN---------SWLAN-----QKWT CIOSAREFTIG_1_3_PE57 NOISO VSDNVLRVDAEKLSCVKTLLHKYERPNVPIVLLNTQN---------SWLAN-----QKWT CULQU_1077_PE2 NOISO FEDNVERIHVDEVSPE-QFIERYESIYKPVVIEGVQN---------GWKAL-----EKWT DANRE3_63_PE21 ENSDARG00000034358 VKDNVERADVQRLSPE-EFIQRFEKPYKPVVLLNVED---------SWPAR-----EKWT DASNOGS_542_PE1 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT DIPORGS_524_PE1 NOISO VADNVERADALQLSVG-EFVERYEKPYKPVVLLNAQE---------GWSAQ-----EKWT DROME3R_19_PE82 NOISO FTDNLERIEESQVPES-EFIERFERPYKPVVIRGCTD---------GWLAL-----EKWT ECHTE281550_PE1 NOISO EADNMDRAP-LHLSVE-EFVVRYERPNS-VVLLNIQE---------GWSAQ-----EEWT ECHTEGS_620_PE1 NOISO VADNVERADALQLSVD-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT ECTSI_12_PE336 NOISO GIRGIARERRDDLTPD-QFWRHYEKRRLPVVVSGIPS-------DEGWRAE-----ERWG ERIEUGS_670_PE1 NOISO VADNVERADALQLSVE-EFVERYEKPYKPVVLLNAQE---------GWSAQ-----EKWT FELCAGS_359_PE3 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT FUGRU519_PE27 NOISO VKDSVERVDALQLSPE-EFIQRFERPYKPVVLLNCQE---------NWPAR-----EKWT GASACGROUPXI_17_PE70 NOISO VKDNVERVDAHHLGPD-EFIRRFERPYRPVVLQGCQE---------AWPAR-----EKWT GORGO5_7_PE10 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT HORSE11_6_PE5 NOISO VSDNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT HS17_PE3079 ENSG00000070495 VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT LOXAF49_6_PE7 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT MACEUGS_795_PE1 NOISO VADNVERVDALQLSVE-EFVERYERPYKPVVLLKAQE---------GWSAQ-----EKWT MACMU16_76_PE14 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT MICMUGS_352_PE3 NOISO --DNVDRADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT MICSR_1_PE830 NOISO -GDDIERISAKDVSVE-EFIERFERPCRPCVITDAMD---------GWAAN-----TEWT MONDO2_250_PE9 ENSMODG00000001566 IPDNVERVDALQLSVE-EFVERYERPYKPVVLLKAQE---------GWSAQ-----EKWT MOUSE11_PE4108 ENSMUSG00000056962 VPDNVERADALQLSVK-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT MYOLUGS_462_PE2 NOISO VADNVERADALQLSVE-DFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT NEMVE_8927_PE28 NOISO VNDNIDRIDCNKISRS-EFVEQYERPRKPVVLTHAID---------HWQAS-----RKWT OCHPRGS_360_PE1 NOISO ------RADARQLSVE-EFVERYERPYKPVVLLHAQE---------GWSAP-----EKWT ORNANULTRA430_PE7 NOISO --DNVERADALQLSVQ-EFVERYERPYKPVVLLNAQV---------GWSAQ-----EKWT ORYLA1014_PE2 NOISO VKDNVERVDTRHLSAV-EFIERFERPYKPVVLLHCQD---------SWAAR-----EKWT OSTLU_12_PE171 NOISO HLHAIERISVKTTTKE-EFIERFERTRTPCVITDAME---------DWGCYKNDGGRFWS PANTR17_81_PE17 ENSPTRG00000009690 VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT PEDHC_835_PE20 NOISO VEDNCERINVSDVSPQ-DFIEKYEKWYKPVVICGLQE---------NWKAK-----HKWN PHATR_4_PE173 NOISO --------LDAKFLST-KEFHMYETSGIPCVIRSIPDGYDGGRFASEWAAS-----RYWS PHINF1_2557_PE80 NOISO ESNPIKREHCSELSVK-RFIDEYERPAVPVVIDGVPE-------ADGWGAL-----KHWS PHSOJ1_1449_PE121 NOISO ESNPIKREHCSELSVK-RFIDEYELPEVPVVIDGIPE-------AEGWGAV-----KHWS PHYRM_347_PE4 NOISO EANPIKREHCSELSVK-RFIEEYESPMVPVVIDGIPE-------ADGWGAV-----KHWP POEGU18_8_PE14 NOISO CKDNVERADALQLTVE-EFVERYEKPYKPVVLLNAQV---------GWSAQ-----EKWT PONPY17_70_PE10 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT PROCAGS_604_PE1 NOISO VADNVERADALQLSVE-AFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT RABITUN0145_PE3 NOISO RADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT RAT10_PE2538 ENSRNOG00000000250 VPDNVERADALQLSVK-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT SPETRGS_5110_PE2 NOISO --------------SV-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT SPIPN_1_5937 NOISO SRDCVERINYDEVSEE-EFIRRFEEPAIPVVIEGATR---------TWPAE-----KRWC STRPU_20779_PE1 NOISO ------------------------------------------------------------ TARSYGS_644_PE1 NOISO ------------------------------------------------------------ TETNG3_PE1108 NOISO VKDSVERVDALQITPE-DFIQRFERPYKPVVLLNCQE---------NWPAQ-----EKWT THTRA1_1_11407 NOISO LDHLLPRFDARTMTEA-E-WFAFEALDRPCVIENLMD---------DWKAP-----AKWT THTRA1_1_8501 NOISO DADSVPRVDYKTTDTK-AFVAGYDAGEMPCLLIGATD---------DWKAM-----RKWN TRIAD_1_PE435 NOISO VRDNVERVDVRSITHQ-EFIRQFEKPLKPVVLTGAME---------KWPAM-----KKWT TUPGBGS_5346_PE2 NOISO VADNVERADALQLSVE-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT TURTRGS_3026_PE2 NOISO VADNVERADALQLSVG-EFVERYERPYKPVVLLNAQE---------GWSAQ-----EKWT XENTR178_2_PE28 NOISO VRDNVERVDAAHFTIE-EFIERYEKPYKPVVILNATA---------DWPAQ-----EKWT MATCH CONSENSUS V?DNVER?DA??LSVE?EFVERYERPYKPVVLLNAQE?????????GWSAQ?????EKWT

ACYPI_16299_PE4 NOISO -LERIGK--KYRNQRFKCGEDNQGYSVKMKMKYFVHYMNN-----NKDDSPLYIFDSSYG AEDAE_2225_PE16 AAEL008084 -LERLAK--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMRN-----TTDDSPLYIFDSSFG AEDAE_4634_PE10 NOISO -LERLAK--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMRN-----TTDDSPLYIFDSSFG AILMEGL192595_1_1_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG ALLMA_1_6023 NOISO -PEAFYS--KFKKYKFKVGEDDDGETVYLRYKHFARYCNS---VGLEDDSPLYIFDSSFA ALLMA_1_9354 NOISO -PEVFYN--KYKKYKFKVGEDDDGNTVYLRYKHFARYCNS---VGLEDDSPLYIFDSSFA ANOCA19_6_PE11 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMET-----TRDDSPLYIFDSSYG ANOGA_172_PE170 NOISO -LERLAK--KYRNQKFKCGEDNDGYSVKMKMKYYVEYMRT-----TTDDSPLYIFDSSFG APIME_303_PE18 NOISO -IERLVK--KYRNQKFKCGEDNEGYSVKMKMKYYVRYMLN-----NEDDSPLYIFDSSFG BOVIN19_58_PE7 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG CABRI1_4_PE2016 NOISO -LERLSK--KYRNQNFKCGEDDHGNSVRMKMKYYHDYMLN-----NRDDSPLYIFDSSFA CAEELIV_PE1070 F29B9.4 -VERLSK--KYRNQNFKCGEDDNGNSVRMKMKYYHDYMLN-----NKDDSPLYIFDSSFA CALJA5_131_PE30 ENSCJAG00000013442 -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG CANFA9_8_PE5 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG CAOWC1_1_8400 NOISO -EEKLLR--KFGGQRFKCGEDDEGYPVKLRFRYYVQYMNHGTGRGNRDDSPMYVFDSSFG CAVPO76_3_PE4 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG CHICK18_PE111 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMET-----TRDDSPLYIFDSSYG CHLRE_PE10084 NOISO DPEDMRR--RFGDHKFKVGSDDDGYAVRLRLSHYLAYLQHG----AVDDSPLYVFDGTFA CHOHOGS_636_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG CIOIN3P_2_PE37 NOISO -LERLKK--KYRNQKFKCGEDNDGYSVKLKMKYYIDYMRT-----TKDDSPLYIFDSNYG CIOSAREFTIG_1_3_PE57 NOISO -LERLKK--KYRNQKFKCGEDNDGYSVKMKMKYYIDYMKT-----TRDDSPLYIFDSNYG CULQU_1077_PE2 NOISO -TGRLAK--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMRS-----TTDDSPLYIFDSSFG DANRE3_63_PE21 ENSDARG00000034358 -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYVEYLES-----THDDSPLYIFDSSFG DASNOGS_542_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG DIPORGS_524_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG DROME3R_19_PE82 NOISO -LARLAK--KYRNQKFKCGEDNEGYSVKMKMKYYVEYMQS-----TRDDSPLYIFDSSFG ECHTE281550_PE1 NOISO ----------LECQKFKCGEDN-GCSLKMKVKY--EYMGS-----IRDDRPLYIFD---- ECHTEGS_620_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYLES-----TRDDSPLYIFDSSYG ECTSI_12_PE336 NOISO -LEQLYR--RYGDCKLKCGEDDDGYSVKVKLKYFLRYMDH-----QTDDSPLYIFDSHFD ERIEUGS_670_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG FELCAGS_359_PE3 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG FUGRU519_PE27 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYTEYLES-----TKDDSPLYIFDSSYG GASACGROUPXI_17_PE70 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYMEYLET-----TSDDSPLYIFDSSYG GORGO5_7_PE10 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG HORSE11_6_PE5 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG HS17_PE3079 ENSG00000070495 -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG LOXAF49_6_PE7 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG MACEUGS_795_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG MACMU16_76_PE14 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG MICMUGS_352_PE3 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG MICSR_1_PE830 NOISO -YDKLRA--KFGRHKFKVGSDDDGYAVRLKFNHIHHYVND--PAHMRDDSPLYIFDGSFG MONDO2_250_PE9 ENSMODG00000001566 -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG MOUSE11_PE4108 ENSMUSG00000056962 -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG MYOLUGS_462_PE2 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG NEMVE_8927_PE28 NOISO -LERLAR--KFRHQKFKVGEDDDGYAVKMKMKYYSEYIQH-----NKDDSPLYIFDSSFG OCHPRGS_360_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG ORNANULTRA430_PE7 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG ORYLA1014_PE2 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYMEYLES-----TKDDSPLYIFDSSYG OSTLU_12_PE171 NOISO -VDTLAE--RFREVKFKVGTDDDGYPVRLKMKHIQHYVND--PVHMRDDSPMYAFDGSVF PANTR17_81_PE17 ENSPTRG00000009690 -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG PEDHC_835_PE20 NOISO -LESLGK--KYRNQKFKCGEDNEGYSVKMKLKYYIEYMKT-----TLDDSPLYIFDSSFG PHATR_4_PE173 NOISO -LEKLAADPDLRDRFFKCGEDDDGKSVKVKLKHFIKYLQS-----NADDSPLYIFDTSFE PHINF1_2557_PE80 NOISO -LKKLRK--KYKRVQLKCGEDDHGKSIRMKFKYFMTYINN-----QTDDSPLYIFDSTFD PHSOJ1_1449_PE121 NOISO -LKKLRK--NYKRVMLKCGEDDNGKTIRMKFKYFMTYLNH-----QTDDSPLYIFDSTFD PHYRM_347_PE4 NOISO -LKKLRK--KYKRVELKCGEDDNGKSIRMKFKYFMAYLND-----QTDDSPLYIFDSTFE POEGU18_8_PE14 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMET-----TRDDSPLYIFDSSYG PONPY17_70_PE10 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG PROCAGS_604_PE1 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG RABITUN0145_PE3 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG RAT10_PE2538 ENSRNOG00000000250 -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG SPETRGS_5110_PE2 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG SPIPN_1_5937 NOISO -PESFLD--TYREEKFKVGEDDDGDPVYLPVKYFMHYALV-SGEAAKDDSPLYIFDSTFG STRPU_20779_PE1 NOISO -------------------------------------------------------MKNNL TARSYGS_644_PE1 NOISO ------------------------------------------------------------ TETNG3_PE1108 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYTEYLET-----TKDDSPLYIFDSSYG THTRA1_1_11407 NOISO -PRRFMR--KYADKTFDVGSFNY---TDMTWAQFVRYALT-----NDDDSPLYVFDPYYG THTRA1_1_8501 NOISO -RAKFSK--RFGSSRFDVGSYNH---TYMTYEQYLRYCDT-----NTDDSPLYIFEPQYA TRIAD_1_PE435 NOISO -IERLKR--KYKNQRFKCGEDDEGYSVKVKLKHLLEYMKH-----QDDDSPFYIFDGSFA TUPGBGS_5346_PE2 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG TURTRGS_3026_PE2 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES-----TRDDSPLYIFDSSYG XENTR178_2_PE28 NOISO -LERLKR--KYRNQKFKCGEDNDGYSVKMKMKYYIEYLEG-----TRDDSPLYIFDSSYG MATCH CONSENSUS ?LERLKR??KYRNQKFKCGEDNDGYSVKMKMKYYIEYMES?????TRDDSPLYIFDSSYG

ACYPI_16299_PE4 NOISO DHHR---------------------------------RKKLLDDYDIPLYFQDD---LFK AEDAE_2225_PE16 AAEL008084 EHHR---------------------------------RKKLLEDYDIPLYFRDD---LFK AEDAE_4634_PE10 NOISO EHHR---------------------------------RKKLLEDYDIPLYFRDD---LFK AILMEGL192595_1_1_PE1 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ ALLMA_1_6023 NOISO DRKVGKNGD------------------------PPRPMRPILDDYEVPKYFSDD---LFD ALLMA_1_9354 NOISO DRKVGKNGD------------------------LPRPMRPILDDYEVPKYFSDD---LFD ANOCA19_6_PE11 NOISO EHPK---------------------------------RRKLLEDYRVPKFFTDD---LFK ANOGA_172_PE170 NOISO EHHR---------------------------------RRKLLEDYEVPLYFRDD---LFK APIME_303_PE18 NOISO EHPR---------------------------------RKKLLEDYVIPKYFRDD---LFQ BOVIN19_58_PE7 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ CABRI1_4_PE2016 NOISO ERRK---------------------------------TKKLSEDYKVPKFFEDD---LFH CAEELIV_PE1070 F29B9.4 ERRK---------------------------------TKKLSEDYSVPKFFEDD---LFH CALJA5_131_PE30 ENSCJAG00000013442 EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ CANFA9_8_PE5 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ CAOWC1_1_8400 NOISO KHRK---------------------------------KKQLLDDYTVPKFFRDD---LFK CAVPO76_3_PE4 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ CHICK18_PE111 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ CHLRE_PE10084 NOISO DRAG---------------------------------SKAMRRDYEVPAYFRED---LFG CHOHOGS_636_PE1 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ CIOIN3P_2_PE37 NOISO EHPK---------------------------------RKQLLEDFEIPNYFKDD---LFR CIOSAREFTIG_1_3_PE57 NOISO EHNK---------------------------------RKQLLEDFEIPKYFKDD---LFR CULQU_1077_PE2 NOISO EHHR---------------------------------RKKLLEDYDIPLYFRDD---LFK DANRE3_63_PE21 ENSDARG00000034358 EHAK---------------------------------RRKLLEDYQVPLFFRDD---LFQ DASNOGS_542_PE1 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ DIPORGS_524_PE1 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ DROME3R_19_PE82 NOISO EHHR---------------------------------RRKLLDDYVVPKYFRDD---LFQ ECHTE281550_PE1 NOISO EHPQ---------------------------------IRKLLEDCKAPKFT--D---LFQ ECHTEGS_620_PE1 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ ECTSI_12_PE336 NOISO DHEV---------------------------------AKGLLEDFFVPHYFPDD---LFS ERIEUGS_670_PE1 NOISO EHPK---------------------------------RKKLLEDYKVPKFFTDD---LFQ FELCAGS_359_PE3 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ FUGRU519_PE27 NOISO EHAK---------------------------------RRKLLDDYQVPVFFRDD---LFQ GASACGROUPXI_17_PE70 NOISO EHAK---------------------------------RRKLLEDYQVPVFFRDD---LFQ GORGO5_7_PE10 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ HORSE11_6_PE5 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ HS17_PE3079 ENSG00000070495 EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ LOXAF49_6_PE7 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ MACEUGS_795_PE1 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ MACMU16_76_PE14 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ MICMUGS_352_PE3 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ MICSR_1_PE830 NOISO DKEG---------------------------------SQPLLKDYDVPKYFKED---LFR MONDO2_250_PE9 ENSMODG00000001566 EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ MOUSE11_PE4108 ENSMUSG00000056962 EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ MYOLUGS_462_PE2 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ NEMVE_8927_PE28 NOISO EHPV---------------------------------KKKLLEEYEVPRFFADD---LFR OCHPRGS_360_PE1 NOISO EHPK---------------------------------RKKLLEDYKVPKFFTDD---LFQ ORNANULTRA430_PE7 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ ORYLA1014_PE2 NOISO EHAK---------------------------------RQKLLEDYEVPVFFRDD---LFQ OSTLU_12_PE171 NOISO DKPE---------------------------------TKSLLEDFKIPDWFEED---LFK PANTR17_81_PE17 ENSPTRG00000009690 EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ PEDHC_835_PE20 NOISO EHAR---------------------------------RKKLLDDYEVPIYFRDD---LLH PHATR_4_PE173 NOISO EDRK---------------------------------AKRVLADYRVPSYFSDD---LFQ PHINF1_2557_PE80 NOISO DHKD---------------------------------TKPLLDDYNVPKYFPED---LFS PHSOJ1_1449_PE121 NOISO DHKD---------------------------------TKPLLDDYKVPKYFPED---LFS PHYRM_347_PE4 NOISO DHKD---------------------------------TKPLLDDYKVPKYFPED---LFS POEGU18_8_PE14 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ PONPY17_70_PE10 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ PROCAGS_604_PE1 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ RABITUN0145_PE3 NOISO EHPK---------------------------------RRKLLEDYRVPKFFTDD---LFQ RAT10_PE2538 ENSRNOG00000000250 EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ SPETRGS_5110_PE2 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ SPIPN_1_5937 NOISO ERKYNNSGRSKRRQKKQKSKRALEGEDWDSERKESQPTCKLLEDYEVPKYFRDD---LFR STRPU_20779_PE1 NOISO SHPK---------------------------------RKKLLEDYVVPHFFQDD---LFQ TARSYGS_644_PE1 NOISO ------------------------------------------------------------ TETNG3_PE1108 NOISO EHAK---------------------------------RRKLLEDYQVPVFFRDD---LFQ THTRA1_1_11407 NOISO SKYP-----------------------------------KLLQQYTVPRFFRDD---YHQ THTRA1_1_8501 NOISO TKFP-----------------------------------KLLKEFSIPKYFTPEDMDLQS TRIAD_1_PE435 NOISO EHSK---------------------------------KKRLLNNYEIPEFFQDD---LFN TUPGBGS_5346_PE2 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ TURTRGS_3026_PE2 NOISO EHPK---------------------------------RRKLLEDYKVPKFFTDD---LFQ XENTR178_2_PE28 NOISO EHPK---------------------------------RKKLLEDYEVPKYFRDD---LFQ MATCH CONSENSUS EHPK?????????????????????????????????RRKLLEDYKVPKFF?DD???LFQ

ACYPI_16299_PE4 NOISO YAGEKKRPPYRWFVMGPSRSGTGIHIDPLGTS-AWNS-LITGHKRWCLFPTHTPK--ELL AEDAE_2225_PE16 AAEL008084 HAGEERRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVSGHKRWCLFPTHTPK--ELL AEDAE_4634_PE10 NOISO HAGEERRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVSGHKRWCLFPTHTPK--ELL AILMEGL192595_1_1_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI ALLMA_1_6023 NOISO MISYSRRPPHRWIVIGPDRSGTGIHLDPLGTS-AWNT-LVVGYKRWCLFPPHISK--QVV ALLMA_1_9354 NOISO MISYSRRPPHRWIVIGPDRSGTGIHLDPLGTS-AWNT-LVVGYKRWCLFPPHISK--QVV ANOCA19_6_PE11 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNS-LVQGHKRWCLFPTSTPR--ELI ANOGA_172_PE170 NOISO HAGEVRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVHGHKRWCLFPTHTPK--ELL APIME_303_PE18 NOISO YAGEHRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LISGHKRWCLFPTHTPR--DLL BOVIN19_58_PE7 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI CABRI1_4_PE2016 NOISO YADHKKRPPHRWFVMGPARSGTAIHIDPLGTS-AWNS-LLLGYKRWVLIPPNAPR--DLV CAEELIV_PE1070 F29B9.4 YADDKKRPPHRWFVMGPARSGTAIHIDPLGTS-AWNS-LLQGHKRWVLIPPIAPR--DLV CALJA5_131_PE30 ENSCJAG00000013442 YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI CANFA9_8_PE5 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI CAOWC1_1_8400 NOISO HAGS-QRPPFRWFVMGPKRSGTGIHIDPLSTS-AWNT-LIQGHKRWCLFPPHAPR--ELV CAVPO76_3_PE4 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI CHICK18_PE111 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI CHLRE_PE10084 NOISO LVGEGRRPPYRWVVMGPARSGSGLHIDPLATS-AWNT-LLAGHKRWALFPPGTPR--AHV CHOHOGS_636_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHVDSLGTS-AWNA-XXXXXXXXXXXXXXXXX--XXX CIOIN3P_2_PE37 NOISO YAGEKKRPPYRWFVMGPGLSGTGIHIDPLGTS-AWNA-LVKGHKRWCMFPNKTPK--EMI CIOSAREFTIG_1_3_PE57 NOISO YSGEKKRPPYRWFVMGPRLSGTGIHIDPLGTS-AWNA-LVSGHKRWCMFPNKTPK--DLI CULQU_1077_PE2 NOISO HAGEERRPPYRWFVMGPGRSGTGIHIDPLGTS-AWNA-LVKGHKRWCLFPTHTPK--ELL DANRE3_63_PE21 ENSDARG00000034358 FAGEKRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTHTPR--ELI DASNOGS_542_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI DIPORGS_524_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI DROME3R_19_PE82 NOISO YCGENRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNT-LIRGHKRWCLFPTQTPK--ELL ECHTE281550_PE1 NOISO SVRGKCSPP-------PPRSGTGIHSDPLGTS-VWS---VVGRKPWCLFLTSMCL--ELI ECHTEGS_620_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI ECTSI_12_PE336 NOISO LVGERRRPPYRWFLVGPKRSGTSVHIDPLGTS-AWNT-VVSGRKLWVLFPPHVDK--NVA ERIEUGS_670_PE1 NOISO YAGEKRRPPYXXXXXXXXXXXXXXXXXXXXXX-XXXX-XXXXXXXXXXXXXXXXX--XXX FELCAGS_359_PE3 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI FUGRU519_PE27 NOISO FAGEKRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTNTPR--EII GASACGROUPXI_17_PE70 NOISO FAGEKRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVHGHKRWCLFPTNTPR--ELI GORGO5_7_PE10 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI HORSE11_6_PE5 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI HS17_PE3079 ENSG00000070495 YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI LOXAF49_6_PE7 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI MACEUGS_795_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI MACMU16_76_PE14 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI MICMUGS_352_PE3 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI MICSR_1_PE830 NOISO HVGEKRRPPYRWVVIGPPRSGSSVHVDPLATS-AWNA-LVSGHKRWALYPPSAGLTKPDL MONDO2_250_PE9 ENSMODG00000001566 YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI MOUSE11_PE4108 ENSMUSG00000056962 YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTNTPR--ELI MYOLUGS_462_PE2 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI NEMVE_8927_PE28 NOISO YAGEKRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNS-VVSGHKRWAMFPTFVPQ--EML OCHPRGS_360_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI ORNANULTRA430_PE7 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI ORYLA1014_PE2 NOISO FAGEKRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTNTPR--ELI OSTLU_12_PE171 NOISO HVGAKRRPPYRWIVFGPPRSGSSVHVDPLATS-AWNA-LISGRKRWALYPPRS-VDKATI PANTR17_81_PE17 ENSPTRG00000009690 YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI PEDHC_835_PE20 NOISO HAGEERRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVVGYKRWCLFPTHTPR--ELI PHATR_4_PE173 NOISO LVSEARRPPYRWFLVGPERSGSTVHVDPLATS-AWNT-LMFGKKRWVLFPPQVPK--QVV PHINF1_2557_PE80 NOISO LVGEDRRPPYRWFLVGPKRSGTTLHLDPLGTS-AWNT-LIVGRKRWVLFPPHLPK--TVV PHSOJ1_1449_PE121 NOISO LVGEDRRPPYRWFLVGPKRSGTTLHLDPLGTS-AWNT-LLVGRKRWVLFPPHLPK--NLV PHYRM_347_PE4 NOISO QVGEDRRPPYRWFLVGPKRSGTTLHLDPLGTS-AWNT-LIVGRKRWVLFPPHVPK--NLV POEGU18_8_PE14 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI PONPY17_70_PE10 NOISO YAGEKRRPPY-------------------------------------------------- PROCAGS_604_PE1 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI RABITUN0145_PE3 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI RAT10_PE2538 ENSRNOG00000000250 YAGEKRRPPYRWFVMGPPRSGTGIHISPGSACSPWLFAEVSAELDECSFHQLKAR--GPL SPETRGS_5110_PE2 NOISO YAGEKRRPPYXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXX--XXX SPIPN_1_5937 NOISO LCGERRRPPYRWMVVGPARSGTGIHVDPLGTS-AWNA-IVYGHKRWVLFPPGTPR--DII STRPU_20779_PE1 NOISO FAGDEKRPPYRWFVMGPGRSGTGIHIDPLGTS-AWNA-LVKGHKRWCMFPTQTPK--ELV TARSYGS_644_PE1 NOISO -----------WFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI TETNG3_PE1108 NOISO FAGEKRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTNTPR--EMI THTRA1_1_11407 NOISO YAGEKDRPLYRWFLVGPKRSGTGIHQDPGNTS-AWNA-LVMGQKRWAFFPPSTKG--SVV THTRA1_1_8501 NOISO CMDDDPRPYYRWVLMGPVRSGTGIHQDPHMTS-AWNA-LIQGHKRWCMFPPHIKG--SIV TRIAD_1_PE435 NOISO YSEEKRRPPHRWFVLGPARSGTGIHIDPLGTS-AWNS-LISGHKRWALFPTTTPK--ELL TUPGBGS_5346_PE2 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTNTPR--ELI TURTRGS_3026_PE2 NOISO YAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTS-AWNA-LVQGHKRWCLFPTSTPR--ELI XENTR178_2_PE28 NOISO FAGEKRRPPYRWFVMGPARSGTGIHIDPLGTS-AWNS-LVHGHKRWCLFPTNVPR--ELI MATCH CONSENSUS YAGEKRRPPYRWFVMGP?RSGTGIHIDPLGTS?AWNA?LVQGHKRWCLFPT?TPR??ELI

ACYPI_16299_PE4 NOISO K----V------------TSAEGGKQRDEAITWFK-IIYPRTQLP-----NWPK---DCS AEDAE_2225_PE16 AAEL008084 K----V------------TGAIGGKQRDEAITWFN-LIYPKTKQL-----DWPS---DCK AEDAE_4634_PE10 NOISO K----V------------TGAIGGKQRDEAITWFN-LIYPKTKQL-----DWPS---DCK AILMEGL192595_1_1_PE1 NOISO K----V------------TREEGGNQQDEAITWFS-VIHPRTQLP-----TWPP---EFK ALLMA_1_6023 NOISO SPRKNSVYYDPRDLRYGIKRVAHTVHDYEAATWFN-EVFPNLAPY-------RD---QLE ALLMA_1_9354 NOISO SPRKNSVYYDPRDMRYGIKRVAHTVHDYEAATWFN-EVYPNLAPY-------RD---QLE ANOCA19_6_PE11 NOISO K----V------------TREDGGNQQDEAITWFR-VIYPRTQLP-----TWPS---EFK ANOGA_172_PE170 NOISO K----V------------TGSIGGKQRDEAITWFS-LIYPRTKQP-----DWPA---DCK APIME_303_PE18 NOISO K----V------------SAAEGGKQRDEAITWFS-IIYPRTKLP-----TWPQ---DCL BOVIN19_58_PE7 NOISO K----V------------TREEGGNQQDEAITWFN-IIYPRTQLP-----TWPP---EFK CABRI1_4_PE2016 NOISO K----P------------MAHEKGKHPDEGITWFQ-TVYKRVRSP-----AWPK---EYA CAEELIV_PE1070 F29B9.4 K----P------------MAHEKGKHPDEGITWFQ-TVYKRVRSP-----SWPK---EYA CALJA5_131_PE30 ENSCJAG00000013442 K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK CANFA9_8_PE5 NOISO K----V------------TREEGGNQQDEAITWFS-IIHPRTQLP-----TWPP---EFK CAOWC1_1_8400 NOISO KPAIS-------------------GMDSEAACWFS-SVYPRTQSP-----NWPA---ELR CAVPO76_3_PE4 NOISO K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK CHICK18_PE111 NOISO K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK CHLRE_PE10084 NOISO LPKEQ-------------------GVEREAVSWFG-KVWPRAQAP-----DWPT---A-R CHOHOGS_636_PE1 NOISO X----X------------XXXXXXXXXXXXXXXXX-XXXXXXXXX-----XXXX---XFK CIOIN3P_2_PE37 NOISO K----V------------KRSEGLLQQDEAITWFK-TIYPRTLSK-----DWPE---EFK CIOSAREFTIG_1_3_PE57 NOISO K----V------------KRSEGLLQQDEAITWFQ-IVYPRTKSK-----DWPQ---EFK CULQU_1077_PE2 NOISO K----V------------TGAIGGKQRDEAITWFN-LIYPKTKQL-----DWPA---DCK DANRE3_63_PE21 ENSDARG00000034358 K----V------------TRDEGGNQQDEAITWFN-VIYPRTQQS-----TWPD---EFR DASNOGS_542_PE1 NOISO K----V------------TREEGGNQQDEAITWFN-VIHPRTQLP-----TWPP---EFK DIPORGS_524_PE1 NOISO K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK DROME3R_19_PE82 NOISO K----V------------TSAMGGKQRDEAITWFS-TIYPRTQLP-----SWPE---QYR ECHTE281550_PE1 NOISO T----V------------NAE-EGDNQDDAITWFI-ILHAQTQL------TWLP---EFK ECHTEGS_620_PE1 NOISO K----V------------TREEGGNQQDEAITWFN-VVHPRTQLP-----TWPP---EFK ECTSI_12_PE336 NOISO KGKDVI----------------RQGEDDEPINYFV-DLLPRIRRKHG---------NSIK ERIEUGS_670_PE1 NOISO X----X------------XXXXXXXXXXXXXXXXX-XXXXXXXXX-----XXXX---XXX FELCAGS_359_PE3 NOISO K----V------------TREEGGNQQDEAITWFS-IIHPRTQLP-----TWPP---EFK FUGRU519_PE27 NOISO K----V------------AREEGGNQQDEAVTWFS-VIYPRTQQP-----NWPP---EFL GASACGROUPXI_17_PE70 NOISO K----V------------SREDGGNQQDEAITWFS-VVYPRTQQP-----NWPP---EFT GORGO5_7_PE10 NOISO K----V------------TRDEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK HORSE11_6_PE5 NOISO K----V------------TREEGGNQQDEAITWFN-IIHPRTQLP-----TWPP---EFK HS17_PE3079 ENSG00000070495 K----V------------TRDEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK LOXAF49_6_PE7 NOISO K----V------------TREEGGNQQDEAITWFN-IIHPRTQLP-----TWPP---EFK MACEUGS_795_PE1 NOISO K----V------------TRDEGGNQQDEAITWFN-TIYPRTQLP-----TWPP---EFK MACMU16_76_PE14 NOISO K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK MICMUGS_352_PE3 NOISO K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK MICSR_1_PE830 NOISO KPK-------------------GIGLDGESVTWFQ-RMYPKTRGK-----EWTEVRGFPK MONDO2_250_PE9 ENSMODG00000001566 K----V------------TRDEGGNQQDEAITWFN-TIYPRTQLP-----TWPP---EFK MOUSE11_PE4108 ENSMUSG00000056962 K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK MYOLUGS_462_PE2 NOISO K----V------------TRDEGGNQQDEAITWFK-IIYPRTQLP-----TWPP---EFK NEMVE_8927_PE28 NOISO K----V------------PSSEGGKQRDEAITWFT-HVYPKTQLS-----SWPE---EYK OCHPRGS_360_PE1 NOISO K----V------------TREEGGSQQDEAITWFH-IIYPRTQLP-----TWPA---EFK ORNANULTRA430_PE7 NOISO K----V------------TRDEGGNQQDEAITWFS-TIYPRTQLG-----TWPA---EFR ORYLA1014_PE2 NOISO K----V------------TREEGGNQQDEAITWFS-VVYPRSQQP-----TWPQ---EFR OSTLU_12_PE171 NOISO KPR-------------------GIGLDGESVTWFN-KMYPRTTTE-----EWKR-QGLPP PANTR17_81_PE17 ENSPTRG00000009690 K----V------------TRDEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK PEDHC_835_PE20 NOISO K----V------------TGIEGGKQRDEAITWFS-VIYPRTKLP-----DWPQ---DCK PHATR_4_PE173 NOISO KGRGLV----------------RRDEDDEAIHYFM-FILPRIKRKAASLKHHE-DYKDFA PHINF1_2557_PE80 NOISO NGKKFI----------------RGDEDDEAVNYFM-DLLPRLKRANS--------PKTLQ PHSOJ1_1449_PE121 NOISO NGKKHV----------------RGNEDDEAVNYFM-DLLPRLKRASP--------PETLQ PHYRM_347_PE4 NOISO NGKKHI----------------RGDEDDEAVNYFM-DLLPRLKRASS--------PETLQ POEGU18_8_PE14 NOISO K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK PONPY17_70_PE10 NOISO ------------------------------------------------------------ PROCAGS_604_PE1 NOISO K----V------------TREEGGNQQDEAITWFS-IIYPRTQLP-----TWPP---EFK RABITUN0145_PE3 NOISO K----V------------TREEGGNQQDEAITWFS-IIYPRTQLP-----TWPP---EFK RAT10_PE2538 ENSRNOG00000000250 R----K------------CWPQ--LAYQEALSLLH-SSVERVQAP-----ELDP---RVS SPETRGS_5110_PE2 NOISO XXXXXX------------XGEERRRQQDEAITWFN-VIYP-TQLP-----PWPP---ESK SPIPN_1_5937 NOISO EPAHV--------------------PDHEAASWFA-HVYPSMEARTSDGKTLGE---RLG STRPU_20779_PE1 NOISO K----P------------SINDGGKQRDEAIMWFS-HVYPRTQDP-----SWPQ---EFK TARSYGS_644_PE1 NOISO K----V------------TREEGGNQQDEAITWFN-VIYPRTQLP-----TWPP---EFK TETNG3_PE1108 NOISO K----V------------SREEGGNQQDEAITWFS-VIYPRTQQP-----GWPP---DFL THTRA1_1_11407 NOISO KPPKG--------------------AGDEGIDWWL-DVYPQLRPR-------AE---ELG THTRA1_1_8501 NOISO KPKKG--------------------EPDSGIYWFH-SVYPRLVDR-------AD---ELG TRIAD_1_PE435 NOISO K----V------------SGKLGGNQRDEAVTWFS-IIYPKTQLS-----TWPL---QFK TUPGBGS_5346_PE2 NOISO K----V------------TREEGGNQQDEAITWFN-IIHPRTQLP-----TWPP---EFK TURTRGS_3026_PE2 NOISO K----V------------TREEGGNQQDEAITWFN-IIYPRTQLP-----TWPP---EFK XENTR178_2_PE28 NOISO K----V------------TRDEGGNQQDEAITWFT-VIYPRTQLP-----SWPP---DFK MATCH CONSENSUS K????V????????????TR?EGGNQQDEAITWF???IYPRTQLP?????TWP????EFK

ACYPI_16299_PE4 NOISO PIEILQGPGETVYVPGGWWHVVLNLDTTIAVTQNFCSRTNFPVVWHKTVRGRPKL----- AEDAE_2225_PE16 AAEL008084 PLEILQKPGETVFVPGGWWHVVLNMDDTIAVTQNFCSKTNFPVVWHKTVRGRPKL----- AEDAE_4634_PE10 NOISO PLEILQKPGETVFVPGGWWHVVLNLATR-------------------------------- AILMEGL192595_1_1_PE1 NOISO PLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKL----- ALLMA_1_6023 NOISO MVEIVQKPGETVYVPGGWHHVVINLSFTVAITQNFCSVANFDQVYLQARAGRPKM----- ALLMA_1_9354 NOISO MVEIVQKPGETVYVPGGWHHVVINLSLTVAITQNYCSVANFDQVYLQARAGRPKM----- ANOCA19_6_PE11 NOISO PLEIVQKPGETVFVPGGWWHVVLNLDTTIAVTQNFASCTNFPVVWHKTVRGRPKL----- ANOGA_172_PE170 NOISO PLEILQKPGETVFVPGGWWHVVLNLDDTVAVTQNFCSRTNFPVVWHKTVRGRPKL----- APIME_303_PE18 NOISO PIEILQNPGETVFVPGGWWHVVLNLDETIAVTQ