Alignment of the gene Family HOG000293418 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL193042_1_1_PE3 ISOFORMIN ------------------VTEGVKCLAHQQSRRADRLLAAGKFEEAISCHKKASAYLSEA AILMEGL193042_1_1_PE4 ENSAMEG00000009590 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKFEEAISCHKKASAYLSEA ANOCA390_1_PE11 NOISO ----------------MEVMEGPLNLAHQQSRKADRSLAVGKYEEAISCHKKAAAYLSDA BOVIN28_19_PE1 ENSBTAG00000012476 CPGSVAPLLQAAVTRGLWKYGRTPHLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA BOVIN28_19_PE2 ISOFORMIN --------------MEVW---KDPHLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA BOVIN28_19_PE3 ISOFORMIN ----------MTILCGFWD------LAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA CALJA12_63_PE8 ENSCJAG00000007142 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA CALJA12_63_PE9 ISOFORMIN ----------------MRSCEALLNHAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA CALJA1_35_PE1 NOISO FPSTTTPLPKATAC-------------------------PGVYG-SKGRTPQAAAYLSEA CANFA4_19_PE2 ENSCAFG00000013055 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKASAYLSEA CANFA4_19_PE3 ISOFORMIN ----------------MWITEGVKCVAHQQSRRADRLLAAGKYEEAISCHKKASAYLSEA CAVPO15_14_PE3 NOISO ----------------FHPTEGPYYEAHQQSRRADRLLAAGKYEEAISCHKKAAACLCEA CHICK6_PE110 NOISO ----------------LNTFHHQVTLAHQQSRKADRLLAAGKYEEAISCHRKAAAYLTEA CHOHOGS_4560_PE1 NOISO ----------------MEVMEGPLNLAHQQSRRADRLLATGKYEEAISCHKKAAAYLSEA DANRE12_10_PE5 NOISO ----------------MEVVDSPLNLAHQQCRKADRLLAAGKFEDAISCHRKAADLLKEA DANRE17_46_PE23 NOISO ----------------MEVIDSPLNRAHHYGRRADQLVMKGKYEEAIECHQEAAELLKEA DASNOGS_4146_PE1 NOISO ----------------MEVMEGPLNLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX DIPORGS_3851_PE1 NOISO ----------------MEVMEGPLNLAHQQSRRADRLLASGKYEEAISCHKKAAAYLCEA ECHTEGS_4902_PE1 NOISO ----------------MEVMEGPLNLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYLSEA FELCAGS_2770_PE1 NOISO ----------------MEVMEGPLNLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYLSEA FUGRU316_PE5 ISOFORMIN ----------------MEVVDSPLNLAHQHCRKADRLLAAGKYEEAILCHGKAADLLTEA FUGRU316_PE6 ENSTRUG00000000608 ----------------MEVVDSPLNLAHQHCRKADRLLAAGKYEEAILCHGKAADLLTEA GASAC48_2_PE13 ENSGACG00000015347 ----------------MEVADSPLNLAHQQCRKADRLLAAGKYEEAISCHGKAADFLTDA GASAC48_2_PE14 ISOFORMIN ----------------MEVADSPLNLAHQQCRKADRLLAAGKYEEAISCHGKAADFLTDA GORGO10_78_PE1 ENSGGOG00000013016 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA GORGO10_78_PE2 ISOFORMIN -----------------VEECESLKEAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA HORSE1_55_PE1 NOISO -------------------MEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA HS10_PE1341 ENSG00000148572 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA HS10_PE1342 ISOFORMIN FPGATTPLPKAAAYPGVYGS---------------------------NGRTPQPAYLSEA HS10_PE1343 ISOFORMIN -------------------MEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA LAMPAGS_1951_PE1 NOISO --------------------------AHQQSRRADRLLAAGKYEEAISCHKKAAGYLSEA LOXAF10_46_PE2 ENSLAFG00000007532 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA LOXAF10_46_PE3 ISOFORMIN ----------------VGVLPSPLLQAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA MACEUGS_5751_PE1 NOISO --------------------------AHQQSRKADRSLAAGKYEEAILCHQKAAXXXXXX MACMU9_77_PE11 ENSMMUG00000017726 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA MACMU9_77_PE12 ISOFORMIN ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA MICMUGS_2528_PE1 NOISO --------------------------AHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA MONDO1_36_PE5 NOISO ----------------MEVMDGPLNLAHQQSRKADRSLAAGKYEEAISCHQKAAAYLSEA MOUSE10_PE821 ENSMUSG00000075000 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHRKATTYLSEA OCHPRGS_2884_PE1 NOISO ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAXXXXXXX ORNAN3_53_PE6 ISOFORMIN ------------------VEENQLVQAHQQSRKADRYLAAGKFEEAISCHKKAAAYLSEA ORNAN3_53_PE7 ENSOANG00000015265 ------------------VEENQLVQAHQQSRKADRYLAAGKFEEAISCHKKAAAYLSEA ORYLA19_22_PE36 NOISO ----------------MEVMDSPLNLAHQQSRKAERLVAAGKYEEAICCHRRAADLLTDA OTOGA13222_PE1 NOISO -------------------------------------------------------YLSEA PANTR10_65_PE10 ISOFORMIN ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA PANTR10_65_PE9 ENSPTRG00000002539 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA PIG14_72_PE3 NOISO ----------------MEVMEGPLNLAHQQSRQADRLLAAGKYEEAISCHKKAAAYLSEA POEGU6_5_PE10 NOISO ----------------MEVMEGPLILASAQSRKADRLLAAGKYEEAISCHKKAAGYLTDA POEGU6_5_PE9 NOISO --------------------------AHQQSRKADRLLAAGKYEEAISCHKKAAGYLTDA PONPY10_75_PE4 ENSPPYG00000002411 ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA PONPY10_75_PE5 ISOFORMIN ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEA PROCAGS_4265_PE1 NOISO ----------------MEVMEGPLNLXXXXXXXXXXXXXXXXXXXAISCHKKAAAYLSEA PTEVAGS_2145_PE1 NOISO ----------------MEVMEGPLNLAHQHSRRADRLLAAGKYEEAISCHKKAAAYLSEA RABIT18_24_PE4 ISOFORMIN ----------------VLILRGFIRGAHQQSRRADRLLAGGKYEEAISCHKKAAAYLSEA RABIT18_24_PE5 ENSOCUG00000006920 ----------------MEVMEGPLNLAHQQSRRADRLLAGGKYEEAISCHKKAAAYLSEA RAT1_PE2255 NOISO -------------------------------------------EEAISCHKKATAYLSEA RAT20_PE614 NOISO ----------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKATAYLSEA SORARGS_4091_PE1 NOISO --------------------------AHQQSRQADRLLAAGKYEEAISCHKKAAAYLSEA SPETR110907_PE1 NOISO -------------------------------------------------------YLSDA SPETR116878_PE1 NOISO ----------------MEVMEAPLNLAYQQSRRADRLLAAGKYEEAISCHKKAAAYLSDA SPETR148055_PE1 NOISO -------------------------------------------------------YLSDA SPETR148057_PE1 NOISO --------------------------AYQQSRRADHLLAAGKYEEAISCHKKAAAYLSDA SPETRGS_3249_PE1 NOISO ----------------MEVMEAPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAXXXXXX TARSY34485_PE1 NOISO --------------------------AHQQSRRADRFLAAGKYEEAISCHKKAAAYLTEA TUPGB140453_PE1 NOISO -------------------------------------------------------YLSEA TURTRGS_1881_PE1 NOISO ----------------MEVMEGPLNLAHQQSRRADRLVAAGKYEEAISCHKKAAAYLSEA XENTR670_PE10 NOISO ----------------MEVMESPLNLAHQQSRKADRFLATGKYEEAIACHKKAAAYLSEA MATCH CONSENSUS ??????????????????????????A?Q??R?ADR??A?GK?EEAI?CH?KA??YL??A

AILMEGL193042_1_1_PE3 ISOFORMIN MKLTQSEQAHLSLELQRESHAKQLLVIQERWTRAKREERLKAQRS---ADREAAAQLQTS AILMEGL193042_1_1_PE4 ENSAMEG00000009590 MKLTQSEQAHLSLELQRESHAKQLLVIQERWTRAKREERLKAQRS---ADREAAAQLQTS ANOCA390_1_PE11 NOISO MKLTQSDQAQLSLQLQKESHLKQILLIQERWKRAKREERLKIQQA---MDRDGVTHPQAS BOVIN28_19_PE1 ENSBTAG00000012476 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKDAAAQLQAS BOVIN28_19_PE2 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKDAAAQLQAS BOVIN28_19_PE3 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKDAAAQLQAS CALJA12_63_PE8 ENSCJAG00000007142 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDVAAYLQAS CALJA12_63_PE9 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDVAAYLQAS CALJA1_35_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKTAQREERLKAQQN---TDKDIAAHLQAS CANFA4_19_PE2 ENSCAFG00000013055 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKEAAAPLQAS CANFA4_19_PE3 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKEAAAPLQAS CAVPO15_14_PE3 NOISO MKLTQSEQARLSLELQRDSHMKQLLLIQERWKRAKREERLKAPQN---TDRD--AHLQAS CHICK6_PE110 NOISO MKLTQSEQAQLSLELQRDSHMKQLLLIQERWKRAKREEKMKAQQN---ADKELAAHLQTS CHOHOGS_4560_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQN---TDKDVATHLQAS DANRE12_10_PE5 NOISO MKLTECEQARLSLELQRDSHVKQQRLIEERWKRAKREDKPRTLQAS-----EQPAR---- DANRE17_46_PE23 NOISO SSMTQSQQVRLSLELQRDRHLQQQRLIQMSCRQTQLK----------------------- DASNOGS_4146_PE1 NOISO XXXXXXXXAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQN---TDKDVATYLQAS DIPORGS_3851_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQN---TDKDVAAHLQAS ECHTEGS_4902_PE1 NOISO MTLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQN---PDKDVATHLQAS FELCAGS_2770_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKDAAAQLQAP FUGRU316_PE5 ISOFORMIN MKTSKFDQACLSMELQRDSHIKQQKLIQERLKREARREATKAQASVAQT-SNTPALL--- FUGRU316_PE6 ENSTRUG00000000608 MKTSKFDQACLSMELQRDSHIKQQKLIQERLKREARREATKAQASVAQT-SNTPALL--- GASAC48_2_PE13 ENSGACG00000015347 MKTTECEQARLSLELQRDSHIKQQRLIQERWKREARREATKARPDQVQ-PPGCPARL--- GASAC48_2_PE14 ISOFORMIN MKTTECEQARLSLELQRDSHIKQQRLIQERWKREARREATKARPDQ-------------- GORGO10_78_PE1 ENSGGOG00000013016 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDVAAHLQTS GORGO10_78_PE2 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDVAAHLQTS HORSE1_55_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---IDKDAAAQLQAS HS10_PE1341 ENSG00000148572 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDAAAHLQTS HS10_PE1342 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDAAAHLQTS HS10_PE1343 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQQG----------------------- LAMPAGS_1951_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDRDAAAQLQAS LOXAF10_46_PE2 ENSLAFG00000007532 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDRDIANYLQAS LOXAF10_46_PE3 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDRDIANYLQAS MACEUGS_5751_PE1 NOISO XXXXXXXXAQLSLELQRDSHMKQLLLIQERWKRAKREERWKAQQT---PDE--TPHLLMS MACMU9_77_PE11 ENSMMUG00000017726 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDVAAHLQAS MACMU9_77_PE12 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDVAAHLQAS MICMUGS_2528_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQN---TDRDVATHLQAS MONDO1_36_PE5 NOISO MKLTQSEQAQLSLELQRDSHMKQLLLIQERWKRAKREERWKAQQT---PDG--TPHLLTS MOUSE10_PE821 ENSMUSG00000075000 MKLTESEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TERDGAPHLQAP OCHPRGS_2884_PE1 NOISO XXXXXXXXAQLSLELQRDSHMKQLLLIQERWKRARREERLRAQQD---LGKDT-----AS ORNAN3_53_PE6 ISOFORMIN MKLTQSEQAQLSLELQRDSHLKQLMLIEERWKRAKREERLRVQHT---TDREAAGPLQAS ORNAN3_53_PE7 ENSOANG00000015265 MKLTQSEQAQLSLELQRDSHLKQLMLIEERWKRAKREERLRVQHT---TDREAAGPLQAS ORYLA19_22_PE36 NOISO MKTTESIQARLSMELQRDSHIKQQQLIQERWKRELRRQASKARPGLAAHLQGGPAPL--- OTOGA13222_PE1 NOISO MTLTQSEQAHLSLELQRDSHMKQLLLIQELWKRAKREERLKAQQN---ADKDVSPHLQTS PANTR10_65_PE10 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN--------------- PANTR10_65_PE9 ENSPTRG00000002539 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDAAAHLQTS PIG14_72_PE3 NOISO MKLTQSEQAHLSLELQRESHMKQLLLIQERWKRAKREERLKAQQS---SDKDAAAQLQAS POEGU6_5_PE10 NOISO MKLTQSEQAQLSLELQRDSHMKQLLLIQERWKRAKREEKLKAQQS---ADKEAATHLQTS POEGU6_5_PE9 NOISO MKLTQSEQAQLSLELQRDSHMKQLLLIQERWKRAKREEKLKAQQS---ADKEAATHLQTS PONPY10_75_PE4 ENSPPYG00000002411 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN---TDKDVAAHLQTS PONPY10_75_PE5 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQN--------------- PROCAGS_4265_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQN---ADKDIAVHLQAC PTEVAGS_2145_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKDAAAQLQAS RABIT18_24_PE4 ISOFORMIN MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLRAQQH---PDRDATAHLQAS RABIT18_24_PE5 ENSOCUG00000006920 MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLRAQQH---PDRDATAHLQAS RAT1_PE2255 NOISO MKLTQSEQAHLSLELQRD--MRQLLVIQERWERAKPEEQLKAQQS---TDRDE-AHLQAS RAT20_PE614 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDRDGVPHLQAS SORARGS_4091_PE1 NOISO MKLTQSEQAHLSLELQRDSHLKQLLLIQERWKRAKREERLKAQQS---TDKEAGAQLQVA SPETR110907_PE1 NOISO MKLTKSEQAHLSLELKRDSHMKQSLLIQEKWKRTKCEERSKA-QN---TDKDVATQLQAS SPETR116878_PE1 NOISO MKLTKSEQAHLSLELKRDSHMKQSLLIQEKWKRAKCEERSKA-QN---TDKDVATQLQAS SPETR148055_PE1 NOISO MKLTKSEQAHLSLELKRDSHMKQALLIQEKWKRAKCEERSKA-QN---TDKDVATQLQAS SPETR148057_PE1 NOISO MKLTKSEQAHLSLELKRDSHMKQALLIQEKWKRAKCEERSKA-QN---TDKDVATQLQAS SPETRGS_3249_PE1 NOISO XXXXXXXXAHLSLELKRDSHMKQSLLIQEKWKRAKCEEQSKA-QN---TDKDVATHLQAS TARSY34485_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLRAQQS---TDKDGAALPQAS TUPGB140453_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQFLLIQERWKRAKREERWKAQQS---MDRDAAAHVQTS TURTRGS_1881_PE1 NOISO MKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQS---TDKDAAAQLQAS XENTR670_PE10 NOISO KKLTQSEQAQLSLELQRESHIKHQLLIQERLKRARREEKLRTQQKAIVAERELSAHLQAS MATCH . **::*::: :: :*: CONSENSUS MKLT?SEQA?LSLELQRDSH?KQ?LLIQERWKRA?REE??KAQQ?????D??????LQ??

AILMEGL193042_1_1_PE3 ISOFORMIN HRPPADDAE-GQG-PLLSEKYSPS-AEKRLPEVQAVFDRDPDTLLFLLQQKS-----EPA AILMEGL193042_1_1_PE4 ENSAMEG00000009590 HRPPADDAE-GQG-PLLSEKYSPS-AEKRLPEVQAVFDRDPDTLLFLLQQKS-----EPA ANOCA390_1_PE11 NOISO SKPSAEESDDQSVAAPASLKYSPS-PEKDLQAKLSVLDRDPDTLLFLLQKRK-----EPQ BOVIN28_19_PE1 ENSBTAG00000012476 HRPSAEDAD-SQS-PLLSQKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKR-----EPT BOVIN28_19_PE2 ISOFORMIN HRPSAEDAD-SQS-PLLSQKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKR-----EPT BOVIN28_19_PE3 ISOFORMIN HRPSAEDAD-SQS-PLLSQKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKR-----EPT CALJA12_63_PE8 ENSCJAG00000007142 HKPSAEDAE-GQS-P-LSQKYSPS-TEQRLPEMQGIFDRDPDTLLYLLQQKS-----EPV CALJA12_63_PE9 ISOFORMIN HKPSAEDAE-GQS-P-LSQKYSPS-TEQRLPEMQGIFDRDPDTLLYLLQQKS-----EPV CALJA1_35_PE1 NOISO HKSSAEDAE-GQS-P-LSQKYSPS-TEQHLPEIQGICDRDPDTVLYLLQQKS-----EPV CANFA4_19_PE2 ENSCAFG00000013055 HRPSSEEAE-GQS-PLLSEKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKR-----EPA CANFA4_19_PE3 ISOFORMIN HRPSSEEAE-GQS-PLLSEKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKR-----EPA CAVPO15_14_PE3 NOISO PRPFAEDAE-HQS-PILAQKHSPC-TEKRLPEVQGIFDRDPDTLLYLLQQKS-----EPA CHICK6_PE110 NOISO FKPSAEESDDQNVLIPVTQKYSPS-TEKHLQDIQGVFDRDPDTLLFLLQKKN-----EPV CHOHOGS_4560_PE1 NOISO HKPSAEDAE-GQS-PLLTQKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKS-----EPT DANRE12_10_PE5 NOISO ----------RH---LHP-------AGV-ADTTSQPPDREYDTWLYLLKNKG-----TVP DANRE17_46_PE23 NOISO ----------GE---------------------------------------LLVSSARPS DASNOGS_4146_PE1 NOISO HKPFAEDAE-GQS-SLLTQKYSPS-TEKHPPEIQGVFDRDPDTLLFLLKQKS-----EPT DIPORGS_3851_PE1 NOISO HKPSAEDGE-AQS-PLLSHKYSPS-VEKHLPEIHGVFDRDPDTLLFLLQRKS-----EPT ECHTEGS_4902_PE1 NOISO HKPSVEDTE-GQS-PLLSQKYSPS-TERHLPEVQGLFDRDPDTLLFLLQQKS-----EPA FELCAGS_2770_PE1 NOISO HKPPSEDAE-GQS-PLLSEKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKR-----EPA FUGRU316_PE5 ISOFORMIN ----SQT---------------------HSSMHGGVKEREFDTLLYQIQRRQTRAAHPLT FUGRU316_PE6 ENSTRUG00000000608 ----SQT---------------------HSSMHGGVKEREFDTLLYQIQRRQTRAAHPLT GASAC48_2_PE13 ENSGACG00000015347 ----TQTQSAGQLQPLGP-------PGLSAAEGAGSREREYDTLLFQLQTRQTGGCQRST GASAC48_2_PE14 ISOFORMIN ---------------------------------------------------------RST GORGO10_78_PE1 ENSGGOG00000013016 HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA GORGO10_78_PE2 ISOFORMIN HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA HORSE1_55_PE1 NOISO HKPSAEDTE-GHS-PLLSQKHSPP-TEKHLSEIQRVFDRDPDTLLFLLQQKS-----EPT HS10_PE1341 ENSG00000148572 HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA HS10_PE1342 ISOFORMIN HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA HS10_PE1343 ISOFORMIN -----------QS-P-L-------------------SQKDPDTLLYLLQQKS-----EPA LAMPAGS_1951_PE1 NOISO HKPPADDAE-GHS-PLLSQKYSPS-TEKHLPEVQGVFDRDPDTLLFLLQQKS-----EPT LOXAF10_46_PE2 ENSLAFG00000007532 HRPSAEDAE-GQS-PLVLQKGSPS-TEKHLPENQRVFDRDPDTLLFLLQQKS-----EPT LOXAF10_46_PE3 ISOFORMIN HRPSAEDAE-GQS-PLVLQKGSPS-TEKHLPENQRVFDRDPDTLLFLLQQKS-----EPT MACEUGS_5751_PE1 NOISO TRPLTEDGSEGPS-VPRSQQFSPA-------SVPGVLDRDPDTLLFLLQKRK-----DPT MACMU9_77_PE11 ENSMMUG00000017726 HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA MACMU9_77_PE12 ISOFORMIN HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA MICMUGS_2528_PE1 NOISO HKPSAEDTE-GQS-PLLSQKYSPS-TEKHLPEIQGIFDRDPDTLLFLLQQKS-----EPT MONDO1_36_PE5 NOISO CKPSAEDGSEGPS-GPRPQLLSPA-PERLSPAVPGVFDRDPDTLLFLLQKRK-----DPT MOUSE10_PE821 ENSMUSG00000075000 PRPS-EDAE-GQS-PLLSQPYIPS-TERRLPEVQGVFDRDPDTLLFLLQQKN-----EPS OCHPRGS_2884_PE1 NOISO HRASAEDAE-GQS-PPRAPKCSPA-AERRLPPIPGVFDRDPDTLLFLLQQRS-----EPA ORNAN3_53_PE6 ISOFORMIN PKAPADDAE-GPA-GPRIPRRSPS-MERRLPEIQGIFDRDPDTLLFLLQKRK-----EPT ORNAN3_53_PE7 ENSOANG00000015265 PKAPADDAE-GPA-GPRIPRRSPS-MERRLPEIQGIFDRDPDTLLFLLQKRK-----EPT ORYLA19_22_PE36 NOISO ----TKSPLSGQPQAH----------GLS-QENGETREREYDTLLYQLQVRQTGSSQTPT OTOGA13222_PE1 NOISO HKPSAEDTE-GQS-PLRFQKYSPS-TERHLPEIHGVFDRDPDTLLFLLQQKS-----EPT PANTR10_65_PE10 ISOFORMIN ------------------------------------------TVLYLLQQKS-----EPA PANTR10_65_PE9 ENSPTRG00000002539 HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA PIG14_72_PE3 NOISO HKPSAEDAD-GES-PLLSQRYSPS-TEKHLPEIQGVFDREPDTLLFLLQQKS-----EPT POEGU6_5_PE10 NOISO YKPSAEDSDDQNVLVPVAQKYSSS-TEKHSQDIRGVFDRDPDTLLFLLQKKK-----EPV POEGU6_5_PE9 NOISO YKPSAEDSDDQNVLVPVAQKYSSS-TEKHSQDIRGVFDRDPDTLLFLLQKKK-----EPV PONPY10_75_PE4 ENSPPYG00000002411 HKPSAEDAE-GQS-P-LSQKYSPS-TEKCLPEIQGIFDRDPDTLLYLLQQKS-----EPA PONPY10_75_PE5 ISOFORMIN ------------------------------------------TVLYLLQQKS-----EPA PROCAGS_4265_PE1 NOISO HRPSVEDAE-GQG-PLLPQKFSPSSTEKQLPENHRVFDRDPDTLLYILQQKS-----EPA PTEVAGS_2145_PE1 NOISO HKPSAEDAE-GQS-LLLSQKYSPS-TEKHRPETQGIFDRDPDTLLFLLQQKS-----EPT RABIT18_24_PE4 ISOFORMIN PRPCAEDAE-GHS-LLLPHKYSPS-TERRLPELRGAFDRDPDTLLFLLQQKS-----EPA RABIT18_24_PE5 ENSOCUG00000006920 PRPCAEDAE-GHS-LLLPHKYSPS-TERRLPELRGAFDRDPDTLLFLLQQKS-----EPA RAT1_PE2255 NOISO HRPS-EDAE-GQS-PH-------PSTEKRLPEVQGVFDWDPDTLLFLLQQKN-----EPS RAT20_PE614 NOISO HRPS-EDSE-GQS-PLLSQTYIPS-TEKRLPEVQGVFDRDPDTLLFLLQQKN-----EPS SORARGS_4091_PE1 NOISO LKPAAEDVD-SQS-SLLF-QNSPS-TEKRLPEIQGVFDRDPDTLLFLLQQKN-----EPT SPETR110907_PE1 NOISO HKPSAEDAE-GQS-PLLSPNYSPC-TEKHLSEIHGVFDRNSETLLCLLQQKS-----EPT SPETR116878_PE1 NOISO HKPSAENAE-SQS-PLLSPNYSPC-TEKHLSEIHGVFDRNSETLLCLLQQKS-----EPT SPETR148055_PE1 NOISO HKPFAEDAE-GQS-PLLSPNYSPC-TEKHLSEIHGVFDRNSETLLCLLQQKS-----EPT SPETR148057_PE1 NOISO HKPFAEDAE-GQS-PLLSPNYSPC-TEKHLSEIHGVFDRNSETLLCLLQQKS-----EPT SPETRGS_3249_PE1 NOISO HKPSAENAE-SQS-PLLSQKYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKS-----EPT TARSY34485_PE1 NOISO HRPSAEDTE-GQS-PLLPQKYRPP-TEKHLPEIQGVFDRDPDTLLFLLQQKS-----EPT TUPGB140453_PE1 NOISO HKPPAEDAE-GHS-PLLAQKYSPS-TERHPPGIQGVFDRDPDTLLFLLQQKN-----EPA TURTRGS_1881_PE1 NOISO HRPSAEDAD-SQS-PLLSQNYSPS-TEKHLPEIQGVFDRDPDTLLFLLQQKS-----EPT XENTR670_PE10 NOISO YRSAADNADSQNTLGSAGQK-SGSNPGKYVQDIPSVLDREPDSLMYLLQRRK-----EPM MATCH CONSENSUS ??????????????????????????E??????????DR?PDTLL?LLQ?K??????EP?

AILMEGL193042_1_1_PE3 ISOFORMIN GPRLGSKAPKDEKTVLEEQATEIADLKRHVELLVAENERLRKENTQLRAEKARLLKGPVE AILMEGL193042_1_1_PE4 ENSAMEG00000009590 GPRLGSKAPKDEKTVLEEQATEIADLKRHVELLVAENERLRKENTQLRAEKARLLKGPVE ANOCA390_1_PE11 NOISO EACVRSKTPKDDKTKMEEQATKIALLERHVEVLLAENERLRQENKQLKAERARLLKSPLE BOVIN28_19_PE1 ENSBTAG00000012476 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAEKARLLKGPTE BOVIN28_19_PE2 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAEKARLLKGPTE BOVIN28_19_PE3 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAEKARLLKGPTE CALJA12_63_PE8 ENSCJAG00000007142 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEMARLLKGPLE CALJA12_63_PE9 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEMARLLKGPLE CALJA1_35_PE1 NOISO EPYIGNKTPKDKKIVIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE CANFA4_19_PE2 ENSCAFG00000013055 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPVD CANFA4_19_PE3 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPVD CAVPO15_14_PE3 NOISO EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLRAEKARLIKGSLE CHICK6_PE110 NOISO ETCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAERARLQKSPVE CHOHOGS_4560_PE1 NOISO EACIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAEERR--KENKQLK--RARLLKG--- DANRE12_10_PE5 NOISO EPCAGSKAQKDDKTRLEEQQTTINDLRKLVDRLVSENQRLKQENERLCAENSRLKK---- DANRE17_46_PE23 NOISO SSVLGCKTAKDDKTRLEEQSTAIADLWRLVLVLLMDNKRLLEENKRLNAEN--------- DASNOGS_4146_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIVDLKRHVEFLVAENERLRRENKQLKVERAKLLKGPVE DIPORGS_3851_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIAELKRHVEFLVVENERLRKENKQLKAEKARLLKGPVD ECHTEGS_4902_PE1 NOISO EPYIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPME FELCAGS_2770_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIADLERHVEFLVAENERLRKENKHLKAEKARLLKGPVE FUGRU316_PE5 ISOFORMIN PPLSGSRTTKDDKTRLEEQQTTIEDLRRLVDHLMDENQRLTADKKRLVAENARLRS---- FUGRU316_PE6 ENSTRUG00000000608 PPLSGSRTTKDDKTRLEEQQTTIEDLRRLVDHLMDENQRLTADKKRLVAENARLRS---- GASAC48_2_PE13 ENSGACG00000015347 PPCPGSKTAKDDKTRLEEQQTTIIDLRRLVDHLMDENERLASDNKQLQSENGRLRA---- GASAC48_2_PE14 ISOFORMIN PPCPGSKTAKDDKTRLEEQQTTIIDLRRLVDHLMDENERLASDNKQLQSENGRLRA---- GORGO10_78_PE1 ENSGGOG00000013016 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE GORGO10_78_PE2 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE HORSE1_55_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIADLKRLVEFLVAENERLRKENKQLKAEKARLLKGPID HS10_PE1341 ENSG00000148572 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE HS10_PE1342 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE HS10_PE1343 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE LAMPAGS_1951_PE1 NOISO ELRIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE LOXAF10_46_PE2 ENSLAFG00000007532 EPCIGSKAPKDDKTIIEEQATKIAALKRHVEFLVAENERLRKENKQLKAEKARLLKGPVE LOXAF10_46_PE3 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIAALKRHVEFLVAENERLRKENKQLKAEKARLLKGPVE MACEUGS_5751_PE1 NOISO ELCPGSKVPKDDKTTIEEQATKIADLKRHVEFLVADNERLRRENKQLRAEKAKLQKAPPE MACMU9_77_PE11 ENSMMUG00000017726 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE MACMU9_77_PE12 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE MICMUGS_2528_PE1 NOISO EPCIGSK-PKDDKTIIEEQATKIAELKRHVEFLVAENERLRKENKQLKAEKARLIKGPIE MONDO1_36_PE5 NOISO EPCTVSKAPKDDKTIIEEQATKIADLKRHVEFLVADNERLRRENKQLRAEKARLQKAPLE MOUSE10_PE821 ENSMUSG00000075000 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGTAE OCHPRGS_2884_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIADLMRHVEFLVAENERLRKENKQLKAEKARLLKGPVE ORNAN3_53_PE6 ISOFORMIN ETCIGSRAPKDDKTIIEEQATQIEDLKRHVEFLVAENDRLRRENRQLKADKARLQKAPRD ORNAN3_53_PE7 ENSOANG00000015265 ETCIGSRAPKDDKTIIEEQATQIEDLKRHVEFLVAENDRLRRENRQLKADKARLQKAPRD ORYLA19_22_PE36 NOISO PSCAGSKTTKDDKTRLEEQQTTIKDLRRLVDHLLNENQRLTADNERLRSENVRLQS---- OTOGA13222_PE1 NOISO EPCMGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE PANTR10_65_PE10 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE PANTR10_65_PE9 ENSPTRG00000002539 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE PIG14_72_PE3 NOISO ELCIGSKTPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPVE POEGU6_5_PE10 NOISO EACIGSKAPKDDKTIIEEQATKIADLKQLIESLVAENERLRRENKQLKAERARLQKSPVD POEGU6_5_PE9 NOISO EACIGSKAPKDDKTIIEEQATKIADLKQLIESLVAENERLRRENKQLKAERARLQKSPVD PONPY10_75_PE4 ENSPPYG00000002411 EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE PONPY10_75_PE5 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIE PROCAGS_4265_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLRAEKARLLKGPLE PTEVAGS_2145_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARRLKGSVE RABIT18_24_PE4 ISOFORMIN EPCIGSKAPKDDKTIIEEQATKIADLMKHVEFLVAENERLRKENKQLKAEKARLLKGPVE RABIT18_24_PE5 ENSOCUG00000006920 EPCIGSKAPKDDKTIIEEQATKIADLMKHVEFLVAENERLRKENKQLKAEKARLLKGPVE RAT1_PE2255 NOISO EPCIGSKAPKDDKTIIEEQATKTAELKRHVEFLVAENERLRKENKQLKAEKARLLKGPTE RAT20_PE614 NOISO EPCIGSKAPKDDKTIIEEQATKIAELKRHVEFLVAENERLRKENKQLKAEKARLLKGPAE SORARGS_4091_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLKKENKQLRAEKARLLKSPIE SPETR110907_PE1 NOISO QPCIGSKAPKDDKTIIENQATKIADLKRHVECLVAENERLRKENKALKAEKARLVKVPVD SPETR116878_PE1 NOISO QPCIGSKAPKDDKTIIENQATKIADLKRHVECLVAENERLRKENKALKAEKARLVKVPVD SPETR148055_PE1 NOISO QPCIRSKAPKDDKTIIENQATKIADLKRHVECLVAENERLRKENKALKAEKARLVKVPVH SPETR148057_PE1 NOISO QPCIGSKAPKDDKTIIENQATKIADLKRHVECLVAENERLRKENKALKAEKARLVKVPVD SPETRGS_3249_PE1 NOISO EPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPVD TARSY34485_PE1 NOISO EPCLGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPVE TUPGB140453_PE1 NOISO EPCMGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAEKTRLVKGPVE TURTRGS_1881_PE1 NOISO ELCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAEKARLLKGPIE XENTR670_PE10 NOISO ETCKVSKAPKDDKTKLEEQATTIKELNQLVDTLLAENEALRKENKKLRAEVARLQKNP-E MATCH : **.* :*:* * * : : *: :: :: * CONSENSUS E?C?GSKAPKDDKTIIEEQATKIADLKRHVE?LVAENERLR?ENKQL?AE?ARL?K?P??

AILMEGL193042_1_1_PE3 ISOFORMIN KELDVDADFVEKSELWNLPPRSDTAA--ASASWQKFA-AGTGKAKDIPIPSLPPLDFPSP AILMEGL193042_1_1_PE4 ENSAMEG00000009590 KELDVDADFVEKSELWNLPPRSDTAA--ASASWQKFA-AGTGKAKDIPIPSLPPLDFPSP ANOCA390_1_PE11 NOISO KELDVDADFVEKSELWGLQQHSETAAATSASSWQKFT-SSAGKAKDIPIPSLPPLDIPSP BOVIN28_19_PE1 ENSBTAG00000012476 KELDVDADFVEKSELWSLPPHSETAA--ASSTWQKFA-SNTGKAKDIPIPNLPPLDFPSP BOVIN28_19_PE2 ISOFORMIN KELDVDADFVEKSELWSLPPHSETAA--ASSTWQKFA-SNTGKAKDIPIPNLPPLDFPSP BOVIN28_19_PE3 ISOFORMIN KELDVDADFVEKSELWSLPPHSETAA--ASSTWQKFA-SNTGKAKDIPIPNLPPLDFPSP CALJA12_63_PE8 ENSCJAG00000007142 KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP CALJA12_63_PE9 ISOFORMIN KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP CALJA1_35_PE1 NOISO KEVYIDADFVEMSALQSLPPHSETAI--ASSTLQKFA-ANTWKAKDIPIPNLPPLDFPSP CANFA4_19_PE2 ENSCAFG00000013055 KELDVDADFVEKSELWSLPPHSETAA--ASSTWQKFA-SSTGKAKDIPIPNLPPLDFPSP CANFA4_19_PE3 ISOFORMIN KELDVDADFVEKSELWSLPPHSETAA--ASSTWQKFA-SSTGKAKDIPIPNLPPLDFPSP CAVPO15_14_PE3 NOISO KELDVDADFVEKSELWSLSPHSENAA--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP CHICK6_PE110 NOISO KELDVDADFVEKSELWGLQQHSETAS--SAASWQDFA-TTAGKAKDIPIPNLPPLDIPSP CHOHOGS_4560_PE1 NOISO ------------------------------------------------------------ DANRE12_10_PE5 NOISO -EHYAD----ADSELWVLPQPNEE-----------------RKAKDIPIPQLPPLEMPTQ DANRE17_46_PE23 NOISO ------------------------------------------------------------ DASNOGS_4146_PE1 NOISO KELDVDTDFVEKSELWSLPPHSETAT--S--SWQ-FA-ANTG------------------ DIPORGS_3851_PE1 NOISO KELDVDADFVEKSELWSLPPQAEAAT--ASSTWQKFS-ASTGKAKDIPIPSLPPLDFPSP ECHTEGS_4902_PE1 NOISO KELDVDTDFVEKSELWSLPPHSETAT--ASSTWQKFA-TNTGKAKDIPIPNLPPLDFPSP FELCAGS_2770_PE1 NOISO KELDVDADFVEKSELWSLPPHSETAT--ASPTWQKFS-ANTGKAKDIPIPNLPPLDFPSP FUGRU316_PE5 ISOFORMIN -E---SADFVERSELWVLPQAAAVQE----------RRSTGKVGSEIAIPQLPPLEMPAQ FUGRU316_PE6 ENSTRUG00000000608 -E---SADFVERSELWVLPQAAAVQE----------RRSTGKVGSEIAIPQLPPLEMPAQ GASAC48_2_PE13 ENSGACG00000015347 -EAVEAVDFVERSELWVLPQAGGAMGTG-----SGQERKGTGKGKEIAIPQLPPLEMPAR GASAC48_2_PE14 ISOFORMIN -EAVEAVDFVERSELWVLPQAGGAMGTG-----SGQERKGTGKGKEIAIPQLPPLEMPAR GORGO10_78_PE1 ENSGGOG00000013016 KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP GORGO10_78_PE2 ISOFORMIN KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP HORSE1_55_PE1 NOISO KELDVDADFVEKSELWSLPPHSETAA--ASPTWQKFA-ANTGKAKDIPIPNLPPLDFPSP HS10_PE1341 ENSG00000148572 KELDVDADFVETSELWSLPPHAETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP HS10_PE1342 ISOFORMIN KELDVDADFVETSELWSLPPHAETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP HS10_PE1343 ISOFORMIN KELDVDADFVETSELWSLPPHAETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP LAMPAGS_1951_PE1 NOISO KELDVDADFVEKSELWSLPPHSETAA--ASSTWQKFA-SNTGKAKDIPIPNLPPLDFPSS LOXAF10_46_PE2 ENSLAFG00000007532 KELDVDADFVETSELWSLPPHSETPA--VSSTWQEFA-TNSGKAKDIPIPNLPPLDFPSP LOXAF10_46_PE3 ISOFORMIN KELDVDADFVETSELWSLPPHSETPA--VSSTWQEFA-TNSGKAKDIPIPNLPPLDFPSP MACEUGS_5751_PE1 NOISO KELDVDADFVEKSELWSLPPSAQTAT--ASSPWQEFA-ASTGKSKDIPIPNLPPLDFPSP MACMU9_77_PE11 ENSMMUG00000017726 KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP MACMU9_77_PE12 ISOFORMIN KELDVDADFVETSELWSLPPHRNCYS--LLD-LAEVR-SKYGKPRTFQSPIFLPWIFHLQ MICMUGS_2528_PE1 NOISO KELDVDADFVEKSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP MONDO1_36_PE5 NOISO KELDVDADFVEKSELWSLPPPTETAS--SASAWPEFA-ANTGKAKDIPIPNLPPLDFPSP MOUSE10_PE821 ENSMUSG00000075000 KELDVDADFVEKSELWGLPSHSESAA--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP OCHPRGS_2884_PE1 NOISO KELDVDADFVEKSELWSLPPQPEAAA--ASSTWQKLA-ANPGKAKDIPIPNLPPLDFPSP ORNAN3_53_PE6 ISOFORMIN KELEGDADFVEKSELWGLQPQRNGHG--VLNVAEI--RCRRGRPRTFQFPIFLLWTFRLR ORNAN3_53_PE7 ENSOANG00000015265 KELEGDADFVEKSELWGLQPQSEMAT--ASSTWQKFAAANTGKAKDIPIPNLPPLDFPSP ORYLA19_22_PE36 NOISO -E---AADFVERSELWVLPQPGGAMGGG-----A--DRKIPGKSKEITVPQLPPLEMPAQ OTOGA13222_PE1 NOISO KELEVDADFVEKSELWSLPPPSETAA--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP PANTR10_65_PE10 ISOFORMIN KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP PANTR10_65_PE9 ENSPTRG00000002539 KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP PIG14_72_PE3 NOISO KELDVDADFVEKSELWSLPPHSETAT--ASSTWQKFA-SNPGKAKDIPIPNLPPLDFPSP POEGU6_5_PE10 NOISO KELDVDTDFVEKSELWGLQQHSESAS--SAATWQKFA-TTAGKAKDIPIPNLPPLDIPSP POEGU6_5_PE9 NOISO KELDVDTDFVEKSELWGLQQHSESAS--SAATWQKFA-TTAGKAKDIPIPNLPPLDIPSP PONPY10_75_PE4 ENSPPYG00000002411 KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP PONPY10_75_PE5 ISOFORMIN KELDVDADFVETSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP PROCAGS_4265_PE1 NOISO KELDVDADFVETSELWSLPPLSETPT--ASSTWQKFA-TNTGKAKDIPIPNLPPLDFPSP PTEVAGS_2145_PE1 NOISO KELDVDADFMEKSELWSLQPHSETAT--ASSTWQKFS-ANTGKAKDIPIPNLPPLDFPSP RABIT18_24_PE4 ISOFORMIN KELEVDADFVEKSELWSLPPQSDAAA--ASASWQKFA-ANPGKAKDIPIPNLPPLDFPSP RABIT18_24_PE5 ENSOCUG00000006920 KELEVDADFVEKSELWSLPPQSDAAA--ASASWQKFA-ANPGKAKDIPIPNLPPLDFPSP RAT1_PE2255 NOISO KELDADADFVEKSELWGLQSHSDTVT--ASSTWQKFA-GNT-EAKDIPMPNLLPLDFPSP RAT20_PE614 NOISO KELDVDADFVEKSELWGLPPHSDTAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP SORARGS_4091_PE1 NOISO KELEVDADFVEKSELWSLPPHSETAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP SPETR110907_PE1 NOISO KELNVDTDFIEKSALWSLPLHSDTAT--AFSTWHKFA-ANTGKAKDIPIPNLPSLDFPSP SPETR116878_PE1 NOISO KELNVDADFIEKSALWSLPLHSDTAT--AFSTWHKFA-ANTGKAKDIPIPNLPSLDFSSP SPETR148055_PE1 NOISO KELDVDADFIEKSALWSLPLYSDTAT--ASSTWHKFA-ANTGKAKDIPIPNLPPLDFPSP SPETR148057_PE1 NOISO KELNVDTDFIEKSALWSLPLHSDTA-----------A-ANTGKAKDIPIPNLPSLDFLSP SPETRGS_3249_PE1 NOISO KELDVDADFVEKSELWSLPPHSDTAT--ASSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP TARSY34485_PE1 NOISO KELDVDADFVEKSELWSLPPHSETAT--TSSTWQKFA-ANTGKAKDIPIPNLPPLDFPSP TUPGB140453_PE1 NOISO KELDVDTDFVEKSELWSLPPQSETAA--ASSTWQKFA-ASTGKAKDIPIPSLPPLDFPSP TURTRGS_1881_PE1 NOISO KELDVDADFVEKSELWSLPPHAETAT--ASSTWQRFA-SNTGKAKDIPIPNLPPLDFPSP XENTR670_PE10 NOISO KDLDIDTDFVEKSELWNLQQPTGSAA-NPTSAWQKFV-AHSGKGTDIPIPNLPPLDIPLP MATCH CONSENSUS KEL?VDADFVE?SELW?LP?????????????W??F?????GKAKDIPIP?LPPLD?PSP

AILMEGL193042_1_1_PE3 ISOFORMIN ------ELPLMELSEDI---LKGFMNN-------- AILMEGL193042_1_1_PE4 ENSAMEG00000009590 ------ELPLMELSEDI---LKGFMNN-------- ANOCA390_1_PE11 NOISO ------ELPLLELSEDI---LKGLMNS-------- BOVIN28_19_PE1 ENSBTAG00000012476 ------ELPLMELSEDF---LKGFMNN-------- BOVIN28_19_PE2 ISOFORMIN ------ELPLMELSEDF---LKGFMNN-------- BOVIN28_19_PE3 ISOFORMIN ------ELPLMELSEDF---LKGFMNN-------- CALJA12_63_PE8 ENSCJAG00000007142 ------ELPLMELSEDI---LKGFMNN-------- CALJA12_63_PE9 ISOFORMIN ------ELPLMELSEDI---LKGFMNN-------- CALJA1_35_PE1 NOISO ------ELPLMELSEDI---LKRFMNN-------- CANFA4_19_PE2 ENSCAFG00000013055 ------ELPLMELSEDI---LKGFMSN-------- CANFA4_19_PE3 ISOFORMIN ------ELPLMELSEDI---LKGFMSN-------- CAVPO15_14_PE3 NOISO ------ELPLMELSEDI---LKGFMSN-------- CHICK6_PE110 NOISO ------ELPLLELSEDM---LKGLMNS-------- CHOHOGS_4560_PE1 NOISO ----------------------------------- DANRE12_10_PE5 NOISO E-IPLEDLPGLELPEDILQELDGDK---------- DANRE17_46_PE23 NOISO ----------------------------------- DASNOGS_4146_PE1 NOISO ----------------------------------- DIPORGS_3851_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- ECHTEGS_4902_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- FELCAGS_2770_PE1 NOISO ------ELPLMELSEDI---LKGFMNN-------- FUGRU316_PE5 ISOFORMIN EDLYMYDLPPLELPEDIVKNYMNK----------- FUGRU316_PE6 ENSTRUG00000000608 EDLYMYDLPPLELPEDIENELQELLDRDK------ GASAC48_2_PE13 ENSGACG00000015347 EDLGLDDLPPLELPEDIKHELQELLDRDKMTRDVS GASAC48_2_PE14 ISOFORMIN EDLGLDDLPPLELPEDIKHELQEL----------- GORGO10_78_PE1 ENSGGOG00000013016 ------ELPLMELSEDI---LKGFMNN-------- GORGO10_78_PE2 ISOFORMIN ------ELPLMELSEDI---LKGFMNN-------- HORSE1_55_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- HS10_PE1341 ENSG00000148572 ------ELPLMELSEDI---LKGFMNN-------- HS10_PE1342 ISOFORMIN ------ELPLMELSEDI---LKGFMNN-------- HS10_PE1343 ISOFORMIN ------ELPLMELSEDI---LKGFMNN-------- LAMPAGS_1951_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- LOXAF10_46_PE2 ENSLAFG00000007532 ------ELPLMELSEDI---LKGLMNN-------- LOXAF10_46_PE3 ISOFORMIN ------ELPLMELSEDI---LKGLMNN-------- MACEUGS_5751_PE1 NOISO ------ELPLLELSEDI---LKGLMNS-------- MACMU9_77_PE11 ENSMMUG00000017726 ------ELPLMELSEDI---LKGFMSN-------- MACMU9_77_PE12 ISOFORMIN ------NFPLWSSLRIF------------------ MICMUGS_2528_PE1 NOISO ------ELPLMDLSEDI---LKGLMNN-------- MONDO1_36_PE5 NOISO ------ELPLLELPEDI---LKGLMNS-------- MOUSE10_PE821 ENSMUSG00000075000 ------ELPLMELSEDI---LKGFMND-------- OCHPRGS_2884_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- ORNAN3_53_PE6 ISOFORMIN ------NF--LSWSC-------------------- ORNAN3_53_PE7 ENSOANG00000015265 ------ELPLLELSEDI---LKGLMNS-------- ORYLA19_22_PE36 NOISO EDLCLDDLPPLELPEDIQHELQEL----------- OTOGA13222_PE1 NOISO ------ELPLMDLSEDI---LKGLMNN-------- PANTR10_65_PE10 ISOFORMIN ------ELPLMELSEDI---LKGFMNN-------- PANTR10_65_PE9 ENSPTRG00000002539 ------ELPLMELSEDI---LKGFMNN-------- PIG14_72_PE3 NOISO ------ELPLMELSEDI---LKG------------ POEGU6_5_PE10 NOISO ------ELPLLELSDDI---LKGLMNS-------- POEGU6_5_PE9 NOISO ------ELPLLELSDDI---LKGLMNS-------- PONPY10_75_PE4 ENSPPYG00000002411 ------ELPLMELSEDI---LKGFMNN-------- PONPY10_75_PE5 ISOFORMIN ------ELPLMELSEDI---LKGFMNN-------- PROCAGS_4265_PE1 NOISO ------ELPLMELSEDI---LKGFMNN-------- PTEVAGS_2145_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- RABIT18_24_PE4 ISOFORMIN ------ELPLMELSEDI---LKGFMND-------- RABIT18_24_PE5 ENSOCUG00000006920 ------ELPLMELSEDI---LKGFMND-------- RAT1_PE2255 NOISO ------ELPLMELSEDI---LKGFIKD-------- RAT20_PE614 NOISO ------ELPLMELSEDI---LKGFMND-------- SORARGS_4091_PE1 NOISO ------ELPIMELSEDI---LKGFMNNY------- SPETR110907_PE1 NOISO ------QLPLMELSEDF---LKGIMNN-------- SPETR116878_PE1 NOISO ------QLPLMELSEDF---LKGIMNN-------- SPETR148055_PE1 NOISO ------QLPLMELSEDF---LKGIMNN-------- SPETR148057_PE1 NOISO ------QLPLMELSEDF---LKGIMNN-------- SPETRGS_3249_PE1 NOISO ------ELPLMELSEEI---LRGLTNN-------- TARSY34485_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- TUPGB140453_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- TURTRGS_1881_PE1 NOISO ------ELPLMELSEDI---LKGLMNN-------- XENTR670_PE10 NOISO ------ELPPLELPEDIQSQLKGLMDS-------- MATCH CONSENSUS ???????LPL?ELSEDI???LKG????????????


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