And/or enter a keyword [Help] Keyword: IS IS NOT
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in FASTA format or as a list for further analyses: FASTA LIST
BLASTP 2.0.5 [May-5-1998] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= genomic|GENSCAN_predicted_peptide_1|110_aa (110 letters) Database: sptrembl: Non-redundant SWISSPROT + TREMBL database (from SWISS-PROT Rel. 38 + TrEMBL Rel. 11 + TrEMBL_NEW: Last Updated: Oct 25, 1999) 361,918 sequences; 113,768,070 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value INS_PANTR 110 INSULIN PRECURSOR. 184 1e-46 INS_HUMAN 110 INSULIN PRECURSOR. 184 1e-46 INS_MACFA 110 INSULIN PRECURSOR. 182 1e-45 INS_CERAE 110 INSULIN PRECURSOR. 182 1e-45 INS_RABIT 110 INSULIN PRECURSOR. 169 5e-42 INS_CANFA 110 INSULIN PRECURSOR. 166 4e-41 INS2_MOUSE 110 INSULIN 2 PRECURSOR. 157 2e-38 INS2_RAT 110 INSULIN 2 PRECURSOR. 157 2e-38 INS_HORSE 86 INSULIN PRECURSOR. 157 2e-38 INS_CRILO 110 INSULIN PRECURSOR. 157 3e-38 INS_AOTTR 108 INSULIN PRECURSOR. 156 5e-38 INS1_RAT 110 INSULIN 1 PRECURSOR. 154 2e-37 AAC77920 127 PREPROINSULIN (FRAGMENT). 152 6e-37 INS_PIG 84 INSULIN PRECURSOR. 152 6e-37 INS_PSAOB 110 INSULIN PRECURSOR. 151 2e-36 INS1_MOUSE 108 INSULIN 1 PRECURSOR. 146 6e-35 INS_BOVIN 105 INSULIN PRECURSOR. 145 8e-35 INS_SHEEP 105 INSULIN PRECURSOR. 144 2e-34 INS_RODSP 108 INSULIN PRECURSOR. 132 6e-31 INS_CAVPO 110 INSULIN PRECURSOR. 126 4e-29 INS_OCTDE 109 INSULIN PRECURSOR. 111 2e-24 INS_SELRF 103 INSULIN PRECURSOR (FRAGMENT). 109 6e-24 INS_CHICK 107 INSULIN PRECURSOR. 106 4e-23 INS2_XENLA 106 INSULIN 2 PRECURSOR. 105 1e-22 INS1_XENLA 106 INSULIN 1 PRECURSOR. 104 3e-22 INS_ANAPL 81 INSULIN PRECURSOR. 102 1e-21 INS_BALPH 51 INSULIN. 97 4e-20 INS_ELEMA 51 INSULIN. 97 4e-20 INS_ACOCA 51 INSULIN. 95 1e-19 INS_CAMDR 51 INSULIN. 93 5e-19 INS_BALBO 51 INSULIN. 93 5e-19 INS_CAPHI 51 INSULIN. 93 5e-19 INS_FELCA 51 INSULIN. 93 7e-19 BAA82315 115 PREPROINSULIN. 90 3e-18 INS_DIDMA 51 INSULIN. 90 3e-18 INS_ANSAN 51 INSULIN. 87 3e-17 INS_LOPPI 116 INSULIN PRECURSOR. 87 5e-17 AAD22742 113 INSULIN PRECURSOR. 85 2e-16 INS_ONCKE 105 INSULIN PRECURSOR. 83 5e-16 O73727 108 PREPROINSULIN PRECURSOR. 83 8e-16 INS_CYPCA 108 INSULIN PRECURSOR. 81 2e-15 CAA08766 59 INSULIN (FRAGMENT). 79 9e-15 Q62543 41 INSULIN 2 (FRAGMENT). 78 2e-14 INS_HYDCO 59 INSULIN. 77 3e-14 INS_TORMA 70 INSULIN PRECURSOR (FRAGMENTS). 76 8e-14 INS_MYXGL 115 INSULIN PRECURSOR. 73 9e-13 INS_SQUAC 54 INSULIN. 71 3e-12 INS_CALMI 52 INSULIN. 70 6e-12 Q62542 39 INSULIN 1 (FRAGMENT). 67 5e-11 G1699408 30 INSULIN B CHAIN. 64 3e-10 >INS_PANTR 110 INSULIN PRECURSOR. Length = 110 Score = 184 bits (463), Expect = 1e-46 Identities = 86/86 (100%), Positives = 86/86 (100%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 SLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_HUMAN 110 INSULIN PRECURSOR. Length = 110 Score = 184 bits (463), Expect = 1e-46 Identities = 86/86 (100%), Positives = 86/86 (100%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 SLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_MACFA 110 INSULIN PRECURSOR. Length = 110 Score = 182 bits (456), Expect = 1e-45 Identities = 85/86 (98%), Positives = 85/86 (98%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEG Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEG 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 SLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_CERAE 110 INSULIN PRECURSOR. Length = 110 Score = 182 bits (456), Expect = 1e-45 Identities = 85/86 (98%), Positives = 85/86 (98%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEG Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEG 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 SLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_RABIT 110 INSULIN PRECURSOR. Length = 110 Score = 169 bits (424), Expect = 5e-42 Identities = 78/86 (90%), Positives = 81/86 (93%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK+RRE E+LQVGQ ELGGGPGAG LQP ALE Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKSRREVEELQVGQAELGGGPGAGGLQPSALEL 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 +LQKRGIVEQCCTSICSLYQLENYCN Sbjct: 85 ALQKRGIVEQCCTSICSLYQLENYCN 110 >INS_CANFA 110 INSULIN PRECURSOR. Length = 110 Score = 166 bits (417), Expect = 4e-41 Identities = 77/86 (89%), Positives = 78/86 (90%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE EDLQV VEL G PG G LQPLALEG Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEDLQVRDVELAGAPGEGGLQPLALEG 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 +LQKRGIVEQCCTSICSLYQLENYCN Sbjct: 85 ALQKRGIVEQCCTSICSLYQLENYCN 110 >INS2_MOUSE 110 INSULIN 2 PRECURSOR. Length = 110 Score = 157 bits (394), Expect = 2e-38 Identities = 73/86 (84%), Positives = 77/86 (88%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED QV Q+ELGGGPGAG LQ LALE Sbjct: 25 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAGDLQTLALEV 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 85 AQQKRGIVDQCCTSICSLYQLENYCN 110 >INS2_RAT 110 INSULIN 2 PRECURSOR. Length = 110 Score = 157 bits (394), Expect = 2e-38 Identities = 73/86 (84%), Positives = 77/86 (88%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED QV Q+ELGGGPGAG LQ LALE Sbjct: 25 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAGDLQTLALEV 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 85 ARQKRGIVDQCCTSICSLYQLENYCN 110 >INS_HORSE 86 INSULIN PRECURSOR. Length = 86 Score = 157 bits (394), Expect = 2e-38 Identities = 73/86 (84%), Positives = 74/86 (85%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK EAED QVG+VELGGGPG G LQPLAL G Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKAXXEAEDPQVGEVELGGGPGLGGLQPLALAG 60 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 Q GIVEQCCT ICSLYQLENYCN Sbjct: 61 PQQXXGIVEQCCTGICSLYQLENYCN 86 >INS_CRILO 110 INSULIN PRECURSOR. Length = 110 Score = 157 bits (392), Expect = 3e-38 Identities = 73/86 (84%), Positives = 77/86 (88%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK+RR ED QV Q+ELGGGPGA LQ LALE Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKSRRGVEDPQVAQLELGGGPGADDLQTLALEV 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 85 AQQKRGIVDQCCTSICSLYQLENYCN 110 >INS_AOTTR 108 INSULIN PRECURSOR. Length = 108 Score = 156 bits (390), Expect = 5e-38 Identities = 73/86 (84%), Positives = 77/86 (88%), Gaps = 2/86 (2%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCG HLVEALYLVCGERGFFY PKTRREAEDLQVGQVELGGG GSL P LEG Sbjct: 25 FVNQHLCGPHLVEALYLVCGERGFFYAPKTRREAEDLQVGQVELGGGSITGSLPP--LEG 82 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 +QKRG+V+QCCTSICSLYQL+NYCN Sbjct: 83 PMQKRGVVDQCCTSICSLYQLQNYCN 108 >INS1_RAT 110 INSULIN 1 PRECURSOR. Length = 110 Score = 154 bits (385), Expect = 2e-37 Identities = 72/86 (83%), Positives = 76/86 (87%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED QV Q+ELGGGP AG LQ LALE Sbjct: 25 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVPQLELGGGPEAGDLQTLALEV 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 85 ARQKRGIVDQCCTSICSLYQLENYCN 110 >AAC77920 127 PREPROINSULIN (FRAGMENT). Length = 127 Score = 152 bits (381), Expect = 6e-37 Identities = 74/86 (86%), Positives = 75/86 (87%), Gaps = 2/86 (2%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q G VELGG G G LQ LALEG Sbjct: 44 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVELGG--GLGGLQALALEG 101 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 QKRGIVEQCCTSICSLYQLENYCN Sbjct: 102 PPQKRGIVEQCCTSICSLYQLENYCN 127 >INS_PIG 84 INSULIN PRECURSOR. Length = 84 Score = 152 bits (381), Expect = 6e-37 Identities = 74/86 (86%), Positives = 75/86 (87%), Gaps = 2/86 (2%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q G VELGG G G LQ LALEG Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVELGG--GLGGLQALALEG 58 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 QKRGIVEQCCTSICSLYQLENYCN Sbjct: 59 PPQKRGIVEQCCTSICSLYQLENYCN 84 >INS_PSAOB 110 INSULIN PRECURSOR. Length = 110 Score = 151 bits (377), Expect = 2e-36 Identities = 70/86 (81%), Positives = 75/86 (86%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK RR +D Q+ Q+ELGG PGAG L+ LALE Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKFRRGVDDPQMPQLELGGSPGAGDLRALALEV 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 + QKRGIVEQCCT ICSLYQLENYCN Sbjct: 85 ARQKRGIVEQCCTGICSLYQLENYCN 110 >INS1_MOUSE 108 INSULIN 1 PRECURSOR. Length = 108 Score = 146 bits (364), Expect = 6e-35 Identities = 70/86 (81%), Positives = 74/86 (85%), Gaps = 2/86 (2%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED QV Q+ELGG P G LQ LALE Sbjct: 25 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVEQLELGGSP--GDLQTLALEV 82 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 83 ARQKRGIVDQCCTSICSLYQLENYCN 108 >INS_BOVIN 105 INSULIN PRECURSOR. Length = 105 Score = 145 bits (363), Expect = 8e-35 Identities = 69/86 (80%), Positives = 71/86 (82%), Gaps = 5/86 (5%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E QVG +EL GGPGAG LEG Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAG-----GLEG 79 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 QKRGIVEQCC S+CSLYQLENYCN Sbjct: 80 PPQKRGIVEQCCASVCSLYQLENYCN 105 >INS_SHEEP 105 INSULIN PRECURSOR. Length = 105 Score = 144 bits (359), Expect = 2e-34 Identities = 68/86 (79%), Positives = 70/86 (81%), Gaps = 5/86 (5%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E QVG +EL GGPGAG LEG Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAG-----GLEG 79 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 QKRGIVEQCC +CSLYQLENYCN Sbjct: 80 PPQKRGIVEQCCAGVCSLYQLENYCN 105 >INS_RODSP 108 INSULIN PRECURSOR. Length = 108 Score = 132 bits (330), Expect = 6e-31 Identities = 69/87 (79%), Positives = 73/87 (83%), Gaps = 3/87 (3%) Query: 25 FVNQHLCGSHLVEALY-LVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALE 83 FVNQHLCGSHLVEALY LVCGERGFFYTP +RRE ED QVGQVELG GPGAGS Q LALE Sbjct: 24 FVNQHLCGSHLVEALYILVCGERGFFYTPMSRREVEDPQVGQVELGAGPGAGSEQTLALE 83 Query: 84 GSLQKRGIVEQCCTSICSLYQLENYCN 110 + Q R IV+QC + ICSLYQ ENYCN Sbjct: 84 VARQAR-IVQQCTSGICSLYQ-ENYCN 108 >INS_CAVPO 110 INSULIN PRECURSOR. Length = 110 Score = 126 bits (314), Expect = 4e-29 Identities = 59/86 (68%), Positives = 69/86 (79%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FV++HLCGS+LVE LY VC + GFFY PK RRE ED QV Q ELG G GAG LQPLALE Sbjct: 25 FVSRHLCGSNLVETLYSVCQDDGFFYIPKDRRELEDPQVEQTELGMGLGAGGLQPLALEM 84 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 +LQKRGIV+QCCT C+ +QL++YCN Sbjct: 85 ALQKRGIVDQCCTGTCTRHQLQSYCN 110 >INS_OCTDE 109 INSULIN PRECURSOR. Length = 109 Score = 111 bits (274), Expect = 2e-24 Identities = 56/86 (65%), Positives = 64/86 (74%), Gaps = 3/86 (3%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 + +QHLCGS+LVEALY+ CG GF Y P RRE EDLQV Q ELG AG LQP ALE Sbjct: 25 YSSQHLCGSNLVEALYMTCGRSGF-YRPHDRRELEDLQVEQAELG--LEAGGLQPSALEM 81 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 LQKRGIV+QCC +IC+ QL+NYCN Sbjct: 82 ILQKRGIVDQCCNNICTFNQLQNYCN 107 >INS_SELRF 103 INSULIN PRECURSOR (FRAGMENT). Length = 103 Score = 109 bits (270), Expect = 6e-24 Identities = 57/88 (64%), Positives = 61/88 (68%), Gaps = 9/88 (10%) Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL--- 82 VNQHLCGSHLVEALYLVCGERGFFY+PK RR+AE L GP G + L Sbjct: 22 VNQHLCGSHLVEALYLVCGERGFFYSPKARRDAEH------PLVNGPLHGEVGDLPFQQE 75 Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110 E KRGIVEQCC + CSLYQLENYCN Sbjct: 76 EFEKVKRGIVEQCCHNTCSLYQLENYCN 103 >INS_CHICK 107 INSULIN PRECURSOR. Length = 107 Score = 106 bits (263), Expect = 4e-23 Identities = 55/84 (65%), Positives = 58/84 (68%), Gaps = 3/84 (3%) Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86 NQHLCGSHLVEALYLVCGERGFFY+PK RR+ E V G AG L E Sbjct: 27 NQHLCGSHLVEALYLVCGERGFFYSPKARRDVEQPLVSSPLRG---EAGVLPFQQEEYEK 83 Query: 87 QKRGIVEQCCTSICSLYQLENYCN 110 KRGIVEQCC + CSLYQLENYCN Sbjct: 84 VKRGIVEQCCHNTCSLYQLENYCN 107 >INS2_XENLA 106 INSULIN 2 PRECURSOR. Length = 106 Score = 105 bits (259), Expect = 1e-22 Identities = 53/87 (60%), Positives = 58/87 (65%), Gaps = 9/87 (10%) Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL---E 83 NQHLCGSHLVEALYLVCG+RGFFY PK +R+ E QV GP L + E Sbjct: 26 NQHLCGSHLVEALYLVCGDRGFFYYPKIKRDIEQAQV------NGPQDNELDGMQFQPQE 79 Query: 84 GSLQKRGIVEQCCTSICSLYQLENYCN 110 KRGIVEQCC S CSL+QLENYCN Sbjct: 80 YQKMKRGIVEQCCHSTCSLFQLENYCN 106 >INS1_XENLA 106 INSULIN 1 PRECURSOR. Length = 106 Score = 104 bits (256), Expect = 3e-22 Identities = 53/88 (60%), Positives = 59/88 (66%), Gaps = 9/88 (10%) Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL--- 82 VNQHLCGSHLVEALYLVCG+RGFFY PK +R+ E V GP L + L Sbjct: 25 VNQHLCGSHLVEALYLVCGDRGFFYYPKVKRDMEQALV------SGPQDNELDGMQLQPQ 78 Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110 E KRGIVEQCC S CSL+QLE+YCN Sbjct: 79 EYQKMKRGIVEQCCHSTCSLFQLESYCN 106 >INS_ANAPL 81 INSULIN PRECURSOR. Length = 81 Score = 102 bits (251), Expect = 1e-21 Identities = 52/85 (61%), Positives = 57/85 (66%), Gaps = 7/85 (8%) Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALE-GS 85 NQHLCGSHLVEALYLVCGERGFFY+PKT + E L GP G + L + Sbjct: 3 NQHLCGSHLVEALYLVCGERGFFYSPKTXXDVEQ------PLVNGPLHGEVGELPFQHEE 56 Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110 Q GIVEQCC + CSLYQLENYCN Sbjct: 57 YQXXGIVEQCCENPCSLYQLENYCN 81 >INS_BALPH 51 INSULIN. Length = 51 Score = 97.1 bits (238), Expect = 4e-20 Identities = 50/86 (58%), Positives = 50/86 (58%), Gaps = 35/86 (40%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCCTSICSLYQLENYCN Sbjct: 31 -----GIVEQCCTSICSLYQLENYCN 51 >INS_ELEMA 51 INSULIN. Length = 51 Score = 97.1 bits (238), Expect = 4e-20 Identities = 49/86 (56%), Positives = 50/86 (57%), Gaps = 35/86 (40%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPKT Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKT------------------------------ 30 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCCT +CSLYQLENYCN Sbjct: 31 -----GIVEQCCTGVCSLYQLENYCN 51 >INS_ACOCA 51 INSULIN. Length = 51 Score = 95.2 bits (233), Expect = 1e-19 Identities = 48/86 (55%), Positives = 51/86 (58%), Gaps = 35/86 (40%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FV+QHLCGSHLVEALYLVCGERGFFYTPK+ Sbjct: 1 FVBQHLCGSHLVEALYLVCGERGFFYTPKS------------------------------ 30 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 GIV+QCCTSICSLYQLENYCN Sbjct: 31 -----GIVDQCCTSICSLYQLENYCN 51 >INS_CAMDR 51 INSULIN. Length = 51 Score = 93.2 bits (228), Expect = 5e-19 Identities = 47/86 (54%), Positives = 48/86 (55%), Gaps = 35/86 (40%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 F NQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FANQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCC S+CSLYQLENYCN Sbjct: 31 -----GIVEQCCASVCSLYQLENYCN 51 >INS_BALBO 51 INSULIN. Length = 51 Score = 93.2 bits (228), Expect = 5e-19 Identities = 48/86 (55%), Positives = 48/86 (55%), Gaps = 35/86 (40%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCC S CSLYQLENYCN Sbjct: 31 -----GIVEQCCASTCSLYQLENYCN 51 >INS_CAPHI 51 INSULIN. Length = 51 Score = 93.2 bits (228), Expect = 5e-19 Identities = 47/86 (54%), Positives = 48/86 (55%), Gaps = 35/86 (40%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCC +CSLYQLENYCN Sbjct: 31 -----GIVEQCCAGVCSLYQLENYCN 51 >INS_FELCA 51 INSULIN. Length = 51 Score = 92.8 bits (227), Expect = 7e-19 Identities = 47/86 (54%), Positives = 49/86 (56%), Gaps = 35/86 (40%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCC S+CSLYQLE+YCN Sbjct: 31 -----GIVEQCCASVCSLYQLEHYCN 51 >BAA82315 115 PREPROINSULIN. Length = 115 Score = 90.5 bits (221), Expect = 3e-18 Identities = 46/89 (51%), Positives = 58/89 (64%), Gaps = 8/89 (8%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAG---SLQPLALEG 84 QHLCG+HLV+ALYLVCGERGFFYTPK R+ + L GG AG + A + Sbjct: 29 QHLCGAHLVDALYLVCGERGFFYTPK--RDVDPLLGFLPAKSGGAAAGGENEVAEFAFKD 86 Query: 85 SLQ---KRGIVEQCCTSICSLYQLENYCN 110 ++ KRGIVEQCC C+++ L+NYCN Sbjct: 87 QMEMMVKRGIVEQCCHKPCNIFDLQNYCN 115 >INS_DIDMA 51 INSULIN. Length = 51 Score = 90.5 bits (221), Expect = 3e-18 Identities = 47/85 (55%), Positives = 47/85 (55%), Gaps = 35/85 (41%) Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85 VNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 2 VNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------- 30 Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCC SICSLYQLE YCN Sbjct: 31 ----GIVEQCCNSICSLYQLETYCN 51 >INS_ANSAN 51 INSULIN. Length = 51 Score = 87.4 bits (213), Expect = 3e-17 Identities = 45/84 (53%), Positives = 47/84 (55%), Gaps = 35/84 (41%) Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86 NQHLCGSHLVEALYLVCGERGFFY+PKT Sbjct: 3 NQHLCGSHLVEALYLVCGERGFFYSPKT-------------------------------- 30 Query: 87 QKRGIVEQCCTSICSLYQLENYCN 110 GIVEQCC + CSLYQLENYCN Sbjct: 31 ---GIVEQCCENPCSLYQLENYCN 51 >INS_LOPPI 116 INSULIN PRECURSOR. Length = 116 Score = 86.6 bits (211), Expect = 5e-17 Identities = 46/91 (50%), Positives = 62/91 (67%), Gaps = 11/91 (12%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV--ELGGGPGAGS---LQPLAL 82 QHLCGSHLV+ALYLVCG+RGFFY PK R+ + L +G + + GG AG+ + A Sbjct: 29 QHLCGSHLVDALYLVCGDRGFFYNPK--RDVDQL-LGFLPPKSGGAAAAGADNEVAEFAF 85 Query: 83 EGSLQ---KRGIVEQCCTSICSLYQLENYCN 110 + ++ KRGIVEQCC C+++ L+NYCN Sbjct: 86 KDQMEMMVKRGIVEQCCHRPCNIFDLQNYCN 116 >AAD22742 113 INSULIN PRECURSOR. Length = 113 Score = 85.0 bits (207), Expect = 2e-16 Identities = 43/88 (48%), Positives = 59/88 (66%), Gaps = 8/88 (9%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV--ELGGGPGAGSLQPLALEGS 85 QHLCGSHLV+ALYLVCG+RGFFY P RR+ + L +G + + GG G + + Sbjct: 29 QHLCGSHLVDALYLVCGDRGFFYNP--RRDVDPL-LGFLPPKAGGAVVQGGENEVTFKDQ 85 Query: 86 LQ---KRGIVEQCCTSICSLYQLENYCN 110 ++ KRGIVE+CC C+++ L+NYCN Sbjct: 86 MEMMVKRGIVEECCHKPCTIFDLQNYCN 113 >INS_ONCKE 105 INSULIN PRECURSOR. Length = 105 Score = 83.5 bits (203), Expect = 5e-16 Identities = 42/83 (50%), Positives = 53/83 (63%), Gaps = 3/83 (3%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 87 QHLCGSHLV+ALYLVCGE+GFFYTPK R+ + L +G + + Sbjct: 26 QHLCGSHLVDALYLVCGEKGFFYTPK--RDVDPL-IGFLSPKSAKENEEYPFKDQTEMMV 82 Query: 88 KRGIVEQCCTSICSLYQLENYCN 110 KRGIVEQCC C+++ L+NYCN Sbjct: 83 KRGIVEQCCHKPCNIFDLQNYCN 105 >O73727 108 PREPROINSULIN PRECURSOR. Length = 108 Score = 82.7 bits (201), Expect = 8e-16 Identities = 44/90 (48%), Positives = 56/90 (61%), Gaps = 15/90 (16%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS-- 85 QHLCGSHLV+ALYLVCG GFFY PK R+ E L LG P + + + + Sbjct: 27 QHLCGSHLVDALYLVCGPTGFFYNPK--RDVEPL------LGFLPPKSAQETEVADFAFK 78 Query: 86 -----LQKRGIVEQCCTSICSLYQLENYCN 110 ++KRGIVEQCC CS+++L+NYCN Sbjct: 79 DHAELIRKRGIVEQCCHKPCSIFELQNYCN 108 >INS_CYPCA 108 INSULIN PRECURSOR. Length = 108 Score = 81.1 bits (197), Expect = 2e-15 Identities = 43/96 (44%), Positives = 55/96 (56%), Gaps = 27/96 (28%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS-- 85 QHLCGSHLV+ALYLVCG GFFY PK R+ + P G L P + + + Sbjct: 27 QHLCGSHLVDALYLVCGPTGFFYNPK--RDVD------------PPLGFLPPKSAQETEV 72 Query: 86 -----------LQKRGIVEQCCTSICSLYQLENYCN 110 ++KRGIVEQCC CS+++L+NYCN Sbjct: 73 ADFAFKDHAEVIRKRGIVEQCCHKPCSIFELQNYCN 108 >CAA08766 59 INSULIN (FRAGMENT). Length = 59 Score = 79.2 bits (192), Expect = 9e-15 Identities = 35/35 (100%), Positives = 35/35 (100%) Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59 >Q62543 41 INSULIN 2 (FRAGMENT). Length = 41 Score = 78.0 bits (189), Expect = 2e-14 Identities = 35/41 (85%), Positives = 37/41 (89%) Query: 70 GGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110 GGPGAG LQ LALE + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 1 GGPGAGDLQTLALEVAQQKRGIVDQCCTSICSLYQLENYCN 41 >INS_HYDCO 59 INSULIN. Length = 59 Score = 77.3 bits (187), Expect = 3e-14 Identities = 41/83 (49%), Positives = 44/83 (52%), Gaps = 27/83 (32%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 87 Q LCGSHLV+ALY VCGERGFFY+PK RE E L Sbjct: 4 QRLCGSHLVDALYFVCGERGFFYSPKPIRELEPL-------------------------- 37 Query: 88 KRGIVEQCCTSICSLYQLENYCN 110 GIVEQCC + CSL LE YCN Sbjct: 38 -LGIVEQCCHNTCSLANLEGYCN 59 >INS_TORMA 70 INSULIN PRECURSOR (FRAGMENTS). Length = 70 Score = 76.1 bits (184), Expect = 8e-14 Identities = 38/84 (45%), Positives = 44/84 (52%), Gaps = 16/84 (19%) Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86 +QHLCGSHLVEALY VCG +GF+Y PK + L GG Sbjct: 3 SQHLCGSHLVEALYFVCGPKGFYYLPKAXXFVDSLAGYSKHQNGGIS------------- 49 Query: 87 QKRGIVEQCCTSICSLYQLENYCN 110 GIVE CC + CSL+ LE YCN Sbjct: 50 ---GIVEHCCHNTCSLFDLEGYCN 70 >INS_MYXGL 115 INSULIN PRECURSOR. Length = 115 Score = 72.6 bits (175), Expect = 9e-13 Identities = 38/85 (44%), Positives = 44/85 (51%), Gaps = 3/85 (3%) Query: 29 HLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL---EGS 85 HLCG LV ALY+ CG RGFFY P + + L S ++ E Sbjct: 31 HLCGKDLVNALYIACGVRGFFYDPTKMKRDTGALAAFLPLAYAEDNESQDDESIGINEVL 90 Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110 KRGIVEQCC CS+Y LENYCN Sbjct: 91 KSKRGIVEQCCHKRCSIYDLENYCN 115 >INS_SQUAC 54 INSULIN. Length = 54 Score = 70.6 bits (170), Expect = 3e-12 Identities = 36/84 (42%), Positives = 41/84 (47%), Gaps = 33/84 (39%) Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86 +QHLCGSHLVEALY VCG +GF+Y PK Sbjct: 3 SQHLCGSHLVEALYFVCGPKGFYYLPK--------------------------------- 29 Query: 87 QKRGIVEQCCTSICSLYQLENYCN 110 + GIVE CC + CSLY LE YCN Sbjct: 30 BZVGIVEHCCHNTCSLYDLEGYCN 53 >INS_CALMI 52 INSULIN. Length = 52 Score = 69.9 bits (168), Expect = 6e-12 Identities = 37/83 (44%), Positives = 41/83 (48%), Gaps = 34/83 (40%) Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 87 Q LCGSHLV+ALY VCGERGFFY+PK Sbjct: 4 QRLCGSHLVDALYFVCGERGFFYSPK---------------------------------- 29 Query: 88 KRGIVEQCCTSICSLYQLENYCN 110 + GIVEQCC + CSL LE YCN Sbjct: 30 QIGIVEQCCHNTCSLVNLEGYCN 52 >Q62542 39 INSULIN 1 (FRAGMENT). Length = 39 Score = 66.7 bits (160), Expect = 5e-11 Identities = 30/36 (83%), Positives = 32/36 (88%) Query: 75 GSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110 G LQ LALE + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 4 GDLQTLALEVARQKRGIVDQCCTSICSLYQLENYCN 39 >G1699408 30 INSULIN B CHAIN. Length = 30 Score = 64.4 bits (154), Expect = 3e-10 Identities = 27/28 (96%), Positives = 28/28 (99%) Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKT 54 NQHLCGSHLVEALYLVCGERGFFY+PKT Sbjct: 3 NQHLCGSHLVEALYLVCGERGFFYSPKT 30 Database: sptrembl: Non-redundant SWISSPROT + TREMBL database (from SWISS-PROT Rel. 38 + TrEMBL Rel. 11 + TrEMBL_NEW: Last Updated: Oct 25, 1999) Posted date: Nov 8, 1999 9:06 AM Number of letters in database: 113,768,070 Number of sequences in database: 361,918 Lambda K H 0.322 0.141 0.438 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21279034 Number of Sequences: 361918 Number of extensions: 794424 Number of successful extensions: 1963 Number of sequences better than 10: 195 Number of HSP's better than 10.0 without gapping: 187 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 1632 Number of HSP's gapped (non-prelim): 242 length of query: 110 length of database: 113768070 effective HSP length: 47 effective length of query: 63 effective length of database: 96757924 effective search space: 6095749212 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.9 bits) S2: 64 (29.3 bits)