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in FASTA format or as a list for further analyses: FASTA LIST
BLASTP 2.0.5 [May-5-1998] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Grail_seq (120 letters) Database: sptrembl: Non-redundant SWISSPROT + TREMBL database (from SWISS-PROT Rel. 38 + TrEMBL Rel. 11 + TrEMBL_NEW: Last Updated: Oct 25, 1999) 361,918 sequences; 113,768,070 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value INS_PANTR 110 INSULIN PRECURSOR. 146 8e-35 INS_HUMAN 110 INSULIN PRECURSOR. 146 8e-35 INS_MACFA 110 INSULIN PRECURSOR. 143 5e-34 INS_CERAE 110 INSULIN PRECURSOR. 143 5e-34 INS_CANFA 110 INSULIN PRECURSOR. 139 1e-32 INS_RABIT 110 INSULIN PRECURSOR. 133 6e-31 INS_PIG 84 INSULIN PRECURSOR. 131 3e-30 AAC77920 127 PREPROINSULIN (FRAGMENT). 131 3e-30 INS_AOTTR 108 INSULIN PRECURSOR. 127 2e-29 INS_CRILO 110 INSULIN PRECURSOR. 126 7e-29 INS1_RAT 110 INSULIN 1 PRECURSOR. 124 2e-28 INS1_MOUSE 108 INSULIN 1 PRECURSOR. 123 4e-28 INS2_MOUSE 110 INSULIN 2 PRECURSOR. 123 4e-28 INS2_RAT 110 INSULIN 2 PRECURSOR. 123 4e-28 INS_HORSE 86 INSULIN PRECURSOR. 123 5e-28 INS_BOVIN 105 INSULIN PRECURSOR. 122 8e-28 INS_PSAOB 110 INSULIN PRECURSOR. 122 1e-27 INS_SHEEP 105 INSULIN PRECURSOR. 121 2e-27 INS_SELRF 103 INSULIN PRECURSOR (FRAGMENT). 107 4e-23 INS_CHICK 107 INSULIN PRECURSOR. 106 5e-23 INS_CAVPO 110 INSULIN PRECURSOR. 102 1e-21 INS2_XENLA 106 INSULIN 2 PRECURSOR. 102 1e-21 INS1_XENLA 106 INSULIN 1 PRECURSOR. 101 2e-21 INS_BALPH 51 INSULIN. 99 1e-20 INS_RODSP 108 INSULIN PRECURSOR. 99 1e-20 INS_ELEMA 51 INSULIN. 99 1e-20 INS_ANAPL 81 INSULIN PRECURSOR. 98 2e-20 INS_ACOCA 51 INSULIN. 97 4e-20 INS_OCTDE 109 INSULIN PRECURSOR. 96 1e-19 INS_CAMDR 51 INSULIN. 95 2e-19 INS_BALBO 51 INSULIN. 95 2e-19 INS_CAPHI 51 INSULIN. 95 2e-19 INS_FELCA 51 INSULIN. 95 2e-19 INS_DIDMA 51 INSULIN. 92 1e-18 INS_CHIBR 51 INSULIN. 90 4e-18 INS_ANSAN 51 INSULIN. 89 1e-17 INS_ONCKE 105 INSULIN PRECURSOR. 85 2e-16 O73727 108 PREPROINSULIN PRECURSOR. 84 4e-16 BAA82315 115 PREPROINSULIN. 83 1e-15 INS_ALLMI 51 INSULIN. 83 1e-15 AAD22742 113 INSULIN PRECURSOR. 82 2e-15 INS_LEPSP 52 INSULIN. 81 3e-15 INS_CYPCA 108 INSULIN PRECURSOR. 80 6e-15 INS_LOPPI 116 INSULIN PRECURSOR. 80 8e-15 CAA08766 59 INSULIN (FRAGMENT). 79 1e-14 INS_HYDCO 59 INSULIN. 79 1e-14 INS_TORMA 70 INSULIN PRECURSOR (FRAGMENTS). 77 4e-14 INS_MYXGL 115 INSULIN PRECURSOR. 73 1e-12 O42485 74 PROINSULIN (FRAGMENT). 66 1e-10 G1699408 30 INSULIN B CHAIN. 64 3e-10 >INS_PANTR 110 INSULIN PRECURSOR. Length = 110 Score = 146 bits (364), Expect = 8e-35 Identities = 74/88 (84%), Positives = 74/88 (84%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ-------GEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ G P A QPLAL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSL--QPLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 EGSLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_HUMAN 110 INSULIN PRECURSOR. Length = 110 Score = 146 bits (364), Expect = 8e-35 Identities = 74/88 (84%), Positives = 74/88 (84%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ-------GEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ G P A QPLAL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSL--QPLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 EGSLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_MACFA 110 INSULIN PRECURSOR. Length = 110 Score = 143 bits (357), Expect = 5e-34 Identities = 73/88 (82%), Positives = 73/88 (82%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED-------LQGEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED L G P A QPLAL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSL--QPLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 EGSLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_CERAE 110 INSULIN PRECURSOR. Length = 110 Score = 143 bits (357), Expect = 5e-34 Identities = 73/88 (82%), Positives = 73/88 (82%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED-------LQGEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED L G P A QPLAL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSL--QPLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 EGSLQKRGIVEQCCTSICSLYQLENYCN Sbjct: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110 >INS_CANFA 110 INSULIN PRECURSOR. Length = 110 Score = 139 bits (346), Expect = 1e-32 Identities = 70/88 (79%), Positives = 71/88 (80%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ-------GEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE EDLQ G P QPLAL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEDLQVRDVELAGAPGEG--GLQPLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 EG+LQKRGIVEQCCTSICSLYQLENYCN Sbjct: 83 EGALQKRGIVEQCCTSICSLYQLENYCN 110 >INS_RABIT 110 INSULIN PRECURSOR. Length = 110 Score = 133 bits (331), Expect = 6e-31 Identities = 68/88 (77%), Positives = 71/88 (80%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ-------GEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPK+RRE E+LQ G P A QP AL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKSRREVEELQVGQAELGGGPGAG--GLQPSAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 E +LQKRGIVEQCCTSICSLYQLENYCN Sbjct: 83 ELALQKRGIVEQCCTSICSLYQLENYCN 110 >INS_PIG 84 INSULIN PRECURSOR. Length = 84 Score = 131 bits (325), Expect = 3e-30 Identities = 66/84 (78%), Positives = 67/84 (79%), Gaps = 3/84 (3%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQG---EPTAHCCPWQPLALEGSL 96 FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q E Q LALEG Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVELGGGLGGLQALALEGPP 60 Query: 97 QKRGIVEQCCTSICSLYQLENYCN 120 QKRGIVEQCCTSICSLYQLENYCN Sbjct: 61 QKRGIVEQCCTSICSLYQLENYCN 84 >AAC77920 127 PREPROINSULIN (FRAGMENT). Length = 127 Score = 131 bits (325), Expect = 3e-30 Identities = 66/84 (78%), Positives = 67/84 (79%), Gaps = 3/84 (3%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQG---EPTAHCCPWQPLALEGSL 96 FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q E Q LALEG Sbjct: 44 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVELGGGLGGLQALALEGPP 103 Query: 97 QKRGIVEQCCTSICSLYQLENYCN 120 QKRGIVEQCCTSICSLYQLENYCN Sbjct: 104 QKRGIVEQCCTSICSLYQLENYCN 127 >INS_AOTTR 108 INSULIN PRECURSOR. Length = 108 Score = 127 bits (317), Expect = 2e-29 Identities = 63/89 (70%), Positives = 67/89 (74%), Gaps = 13/89 (14%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ--------GEPTAHCCPWQPLA 91 FVNQHLCG HLVEALYLVCGERGFFY PKTRREAEDLQ G T P Sbjct: 25 FVNQHLCGPHLVEALYLVCGERGFFYAPKTRREAEDLQVGQVELGGGSITGSLPP----- 79 Query: 92 LEGSLQKRGIVEQCCTSICSLYQLENYCN 120 LEG +QKRG+V+QCCTSICSLYQL+NYCN Sbjct: 80 LEGPMQKRGVVDQCCTSICSLYQLQNYCN 108 >INS_CRILO 110 INSULIN PRECURSOR. Length = 110 Score = 126 bits (313), Expect = 7e-29 Identities = 65/88 (73%), Positives = 68/88 (76%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED-------LQGEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPK+RR ED L G P A Q LAL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKSRRGVEDPQVAQLELGGGPGAD--DLQTLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 E + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 83 EVAQQKRGIVDQCCTSICSLYQLENYCN 110 >INS1_RAT 110 INSULIN 1 PRECURSOR. Length = 110 Score = 124 bits (309), Expect = 2e-28 Identities = 64/88 (72%), Positives = 67/88 (75%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED-------LQGEPTAHCCPWQPLAL 92 FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED L G P A Q LAL Sbjct: 25 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVPQLELGGGPEAG--DLQTLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 E + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 83 EVARQKRGIVDQCCTSICSLYQLENYCN 110 >INS1_MOUSE 108 INSULIN 1 PRECURSOR. Length = 108 Score = 123 bits (307), Expect = 4e-28 Identities = 62/84 (73%), Positives = 65/84 (76%), Gaps = 3/84 (3%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPT---AHCCPWQPLALEGSL 96 FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED Q E Q LALE + Sbjct: 25 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVEQLELGGSPGDLQTLALEVAR 84 Query: 97 QKRGIVEQCCTSICSLYQLENYCN 120 QKRGIV+QCCTSICSLYQLENYCN Sbjct: 85 QKRGIVDQCCTSICSLYQLENYCN 108 >INS2_MOUSE 110 INSULIN 2 PRECURSOR. Length = 110 Score = 123 bits (307), Expect = 4e-28 Identities = 64/88 (72%), Positives = 67/88 (75%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED-------LQGEPTAHCCPWQPLAL 92 FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED L G P A Q LAL Sbjct: 25 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAG--DLQTLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 E + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 83 EVAQQKRGIVDQCCTSICSLYQLENYCN 110 >INS2_RAT 110 INSULIN 2 PRECURSOR. Length = 110 Score = 123 bits (307), Expect = 4e-28 Identities = 64/88 (72%), Positives = 67/88 (75%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED-------LQGEPTAHCCPWQPLAL 92 FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED L G P A Q LAL Sbjct: 25 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAG--DLQTLAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 E + QKRGIV+QCCTSICSLYQLENYCN Sbjct: 83 EVARQKRGIVDQCCTSICSLYQLENYCN 110 >INS_HORSE 86 INSULIN PRECURSOR. Length = 86 Score = 123 bits (306), Expect = 5e-28 Identities = 64/86 (74%), Positives = 64/86 (74%), Gaps = 5/86 (5%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ-GEPTAHCCP----WQPLALEG 94 FVNQHLCGSHLVEALYLVCGERGFFYTPK EAED Q GE P QPLAL G Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKAXXEAEDPQVGEVELGGGPGLGGLQPLALAG 60 Query: 95 SLQKRGIVEQCCTSICSLYQLENYCN 120 Q GIVEQCCT ICSLYQLENYCN Sbjct: 61 PQQXXGIVEQCCTGICSLYQLENYCN 86 >INS_BOVIN 105 INSULIN PRECURSOR. Length = 105 Score = 122 bits (304), Expect = 8e-28 Identities = 62/88 (70%), Positives = 64/88 (72%), Gaps = 14/88 (15%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE-------DLQGEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E +L G P A L Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAG-------GL 77 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 EG QKRGIVEQCC S+CSLYQLENYCN Sbjct: 78 EGPPQKRGIVEQCCASVCSLYQLENYCN 105 >INS_PSAOB 110 INSULIN PRECURSOR. Length = 110 Score = 122 bits (303), Expect = 1e-27 Identities = 63/88 (71%), Positives = 66/88 (74%), Gaps = 9/88 (10%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED-------LQGEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPK RR +D L G P A + LAL Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKFRRGVDDPQMPQLELGGSPGAG--DLRALAL 82 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 E + QKRGIVEQCCT ICSLYQLENYCN Sbjct: 83 EVARQKRGIVEQCCTGICSLYQLENYCN 110 >INS_SHEEP 105 INSULIN PRECURSOR. Length = 105 Score = 121 bits (300), Expect = 2e-27 Identities = 61/88 (69%), Positives = 63/88 (71%), Gaps = 14/88 (15%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE-------DLQGEPTAHCCPWQPLAL 92 FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E +L G P A L Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAG-------GL 77 Query: 93 EGSLQKRGIVEQCCTSICSLYQLENYCN 120 EG QKRGIVEQCC +CSLYQLENYCN Sbjct: 78 EGPPQKRGIVEQCCAGVCSLYQLENYCN 105 >INS_SELRF 103 INSULIN PRECURSOR (FRAGMENT). Length = 103 Score = 107 bits (264), Expect = 4e-23 Identities = 57/86 (66%), Positives = 61/86 (70%), Gaps = 10/86 (11%) Query: 41 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE------DLQGEPTAHCCPWQPLALEG 94 VNQHLCGSHLVEALYLVCGERGFFY+PK RR+AE L GE P+Q E Sbjct: 22 VNQHLCGSHLVEALYLVCGERGFFYSPKARRDAEHPLVNGPLHGE--VGDLPFQQEEFE- 78 Query: 95 SLQKRGIVEQCCTSICSLYQLENYCN 120 KRGIVEQCC + CSLYQLENYCN Sbjct: 79 -KVKRGIVEQCCHNTCSLYQLENYCN 103 >INS_CHICK 107 INSULIN PRECURSOR. Length = 107 Score = 106 bits (263), Expect = 5e-23 Identities = 56/85 (65%), Positives = 61/85 (70%), Gaps = 10/85 (11%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAED------LQGEPTAHCCPWQPLALEGS 95 NQHLCGSHLVEALYLVCGERGFFY+PK RR+ E L+GE A P+Q E Sbjct: 27 NQHLCGSHLVEALYLVCGERGFFYSPKARRDVEQPLVSSPLRGE--AGVLPFQQEEYE-- 82 Query: 96 LQKRGIVEQCCTSICSLYQLENYCN 120 KRGIVEQCC + CSLYQLENYCN Sbjct: 83 KVKRGIVEQCCHNTCSLYQLENYCN 107 >INS_CAVPO 110 INSULIN PRECURSOR. Length = 110 Score = 102 bits (252), Expect = 1e-21 Identities = 51/86 (59%), Positives = 61/86 (70%), Gaps = 5/86 (5%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPT-----AHCCPWQPLALEG 94 FV++HLCGS+LVE LY VC + GFFY PK RRE ED Q E T QPLALE Sbjct: 25 FVSRHLCGSNLVETLYSVCQDDGFFYIPKDRRELEDPQVEQTELGMGLGAGGLQPLALEM 84 Query: 95 SLQKRGIVEQCCTSICSLYQLENYCN 120 +LQKRGIV+QCCT C+ +QL++YCN Sbjct: 85 ALQKRGIVDQCCTGTCTRHQLQSYCN 110 >INS2_XENLA 106 INSULIN 2 PRECURSOR. Length = 106 Score = 102 bits (251), Expect = 1e-21 Identities = 51/81 (62%), Positives = 55/81 (66%), Gaps = 2/81 (2%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ--GEPTAHCCPWQPLALEGSLQKR 99 NQHLCGSHLVEALYLVCG+RGFFY PK +R+ E Q G Q E KR Sbjct: 26 NQHLCGSHLVEALYLVCGDRGFFYYPKIKRDIEQAQVNGPQDNELDGMQFQPQEYQKMKR 85 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIVEQCC S CSL+QLENYCN Sbjct: 86 GIVEQCCHSTCSLFQLENYCN 106 >INS1_XENLA 106 INSULIN 1 PRECURSOR. Length = 106 Score = 101 bits (249), Expect = 2e-21 Identities = 50/82 (60%), Positives = 56/82 (67%), Gaps = 2/82 (2%) Query: 41 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED--LQGEPTAHCCPWQPLALEGSLQK 98 VNQHLCGSHLVEALYLVCG+RGFFY PK +R+ E + G Q E K Sbjct: 25 VNQHLCGSHLVEALYLVCGDRGFFYYPKVKRDMEQALVSGPQDNELDGMQLQPQEYQKMK 84 Query: 99 RGIVEQCCTSICSLYQLENYCN 120 RGIVEQCC S CSL+QLE+YCN Sbjct: 85 RGIVEQCCHSTCSLFQLESYCN 106 >INS_BALPH 51 INSULIN. Length = 51 Score = 99.1 bits (243), Expect = 1e-20 Identities = 50/81 (61%), Positives = 50/81 (61%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIVEQCCTSICSLYQLENYCN Sbjct: 31 GIVEQCCTSICSLYQLENYCN 51 >INS_RODSP 108 INSULIN PRECURSOR. Length = 108 Score = 99.1 bits (243), Expect = 1e-20 Identities = 58/87 (66%), Positives = 63/87 (71%), Gaps = 8/87 (9%) Query: 40 FVNQHLCGSHLVEALY-LVCGERGFFYTPKTRREAEDLQ-GEPTAHCCPW----QPLALE 93 FVNQHLCGSHLVEALY LVCGERGFFYTP +RRE ED Q G+ P Q LALE Sbjct: 24 FVNQHLCGSHLVEALYILVCGERGFFYTPMSRREVEDPQVGQVELGAGPGAGSEQTLALE 83 Query: 94 GSLQKRGIVEQCCTSICSLYQLENYCN 120 + Q R IV+QC + ICSLYQ ENYCN Sbjct: 84 VARQAR-IVQQCTSGICSLYQ-ENYCN 108 >INS_ELEMA 51 INSULIN. Length = 51 Score = 99.1 bits (243), Expect = 1e-20 Identities = 49/81 (60%), Positives = 50/81 (61%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 FVNQHLCGSHLVEALYLVCGERGFFYTPKT Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKT------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIVEQCCT +CSLYQLENYCN Sbjct: 31 GIVEQCCTGVCSLYQLENYCN 51 >INS_ANAPL 81 INSULIN PRECURSOR. Length = 81 Score = 98.3 bits (241), Expect = 2e-20 Identities = 48/79 (60%), Positives = 52/79 (65%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKRGI 101 NQHLCGSHLVEALYLVCGERGFFY+PKT + E H + Q GI Sbjct: 3 NQHLCGSHLVEALYLVCGERGFFYSPKTXXDVEQPLVNGPLHGEVGELPFQHEEYQXXGI 62 Query: 102 VEQCCTSICSLYQLENYCN 120 VEQCC + CSLYQLENYCN Sbjct: 63 VEQCCENPCSLYQLENYCN 81 >INS_ACOCA 51 INSULIN. Length = 51 Score = 97.1 bits (238), Expect = 4e-20 Identities = 48/81 (59%), Positives = 51/81 (62%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 FV+QHLCGSHLVEALYLVCGERGFFYTPK+ Sbjct: 1 FVBQHLCGSHLVEALYLVCGERGFFYTPKS------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIV+QCCTSICSLYQLENYCN Sbjct: 31 GIVDQCCTSICSLYQLENYCN 51 >INS_OCTDE 109 INSULIN PRECURSOR. Length = 109 Score = 96.0 bits (235), Expect = 1e-19 Identities = 49/84 (58%), Positives = 57/84 (67%), Gaps = 4/84 (4%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTA---HCCPWQPLALEGSL 96 + +QHLCGS+LVEALY+ CG GF Y P RRE EDLQ E QP ALE L Sbjct: 25 YSSQHLCGSNLVEALYMTCGRSGF-YRPHDRRELEDLQVEQAELGLEAGGLQPSALEMIL 83 Query: 97 QKRGIVEQCCTSICSLYQLENYCN 120 QKRGIV+QCC +IC+ QL+NYCN Sbjct: 84 QKRGIVDQCCNNICTFNQLQNYCN 107 >INS_CAMDR 51 INSULIN. Length = 51 Score = 95.2 bits (233), Expect = 2e-19 Identities = 47/81 (58%), Positives = 48/81 (59%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 F NQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FANQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIVEQCC S+CSLYQLENYCN Sbjct: 31 GIVEQCCASVCSLYQLENYCN 51 >INS_BALBO 51 INSULIN. Length = 51 Score = 95.2 bits (233), Expect = 2e-19 Identities = 48/81 (59%), Positives = 48/81 (59%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIVEQCC S CSLYQLENYCN Sbjct: 31 GIVEQCCASTCSLYQLENYCN 51 >INS_CAPHI 51 INSULIN. Length = 51 Score = 95.2 bits (233), Expect = 2e-19 Identities = 47/81 (58%), Positives = 48/81 (59%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIVEQCC +CSLYQLENYCN Sbjct: 31 GIVEQCCAGVCSLYQLENYCN 51 >INS_FELCA 51 INSULIN. Length = 51 Score = 94.8 bits (232), Expect = 2e-19 Identities = 47/81 (58%), Positives = 49/81 (60%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 FVNQHLCGSHLVEALYLVCGERGFFYTPK Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIVEQCC S+CSLYQLE+YCN Sbjct: 31 GIVEQCCASVCSLYQLEHYCN 51 >INS_DIDMA 51 INSULIN. Length = 51 Score = 92.4 bits (226), Expect = 1e-18 Identities = 47/80 (58%), Positives = 47/80 (58%), Gaps = 30/80 (37%) Query: 41 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKRG 100 VNQHLCGSHLVEALYLVCGERGFFYTPK G Sbjct: 2 VNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------G 31 Query: 101 IVEQCCTSICSLYQLENYCN 120 IVEQCC SICSLYQLE YCN Sbjct: 32 IVEQCCNSICSLYQLETYCN 51 >INS_CHIBR 51 INSULIN. Length = 51 Score = 90.5 bits (221), Expect = 4e-18 Identities = 44/81 (54%), Positives = 49/81 (60%), Gaps = 30/81 (37%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKR 99 FVN+HLCGSHLV+ALYLVCG+RGFFYTP Sbjct: 1 FVNKHLCGSHLVDALYLVCGDRGFFYTPMA------------------------------ 30 Query: 100 GIVEQCCTSICSLYQLENYCN 120 GIV+QCCTSIC+LYQLENYCN Sbjct: 31 GIVDQCCTSICTLYQLENYCN 51 >INS_ANSAN 51 INSULIN. Length = 51 Score = 89.3 bits (218), Expect = 1e-17 Identities = 45/79 (56%), Positives = 47/79 (58%), Gaps = 30/79 (37%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKRGI 101 NQHLCGSHLVEALYLVCGERGFFY+PKT GI Sbjct: 3 NQHLCGSHLVEALYLVCGERGFFYSPKT------------------------------GI 32 Query: 102 VEQCCTSICSLYQLENYCN 120 VEQCC + CSLYQLENYCN Sbjct: 33 VEQCCENPCSLYQLENYCN 51 >INS_ONCKE 105 INSULIN PRECURSOR. Length = 105 Score = 85.0 bits (207), Expect = 2e-16 Identities = 44/82 (53%), Positives = 55/82 (66%), Gaps = 6/82 (7%) Query: 43 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQG---EPTAHCCPWQPLALEGSLQ-K 98 QHLCGSHLV+ALYLVCGE+GFFYTPK R+ + L G +A P + + K Sbjct: 26 QHLCGSHLVDALYLVCGEKGFFYTPK--RDVDPLIGFLSPKSAKENEEYPFKDQTEMMVK 83 Query: 99 RGIVEQCCTSICSLYQLENYCN 120 RGIVEQCC C+++ L+NYCN Sbjct: 84 RGIVEQCCHKPCNIFDLQNYCN 105 >O73727 108 PREPROINSULIN PRECURSOR. Length = 108 Score = 83.9 bits (204), Expect = 4e-16 Identities = 44/84 (52%), Positives = 54/84 (63%), Gaps = 8/84 (9%) Query: 43 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQG---EPTAHCCPWQPLALEGS---L 96 QHLCGSHLV+ALYLVCG GFFY PK R+ E L G +A A + + Sbjct: 27 QHLCGSHLVDALYLVCGPTGFFYNPK--RDVEPLLGFLPPKSAQETEVADFAFKDHAELI 84 Query: 97 QKRGIVEQCCTSICSLYQLENYCN 120 +KRGIVEQCC CS+++L+NYCN Sbjct: 85 RKRGIVEQCCHKPCSIFELQNYCN 108 >BAA82315 115 PREPROINSULIN. Length = 115 Score = 82.7 bits (201), Expect = 1e-15 Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 13/89 (14%) Query: 43 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCC--------PWQPLALEG 94 QHLCG+HLV+ALYLVCGERGFFYTPK R+ + L G A A + Sbjct: 29 QHLCGAHLVDALYLVCGERGFFYTPK--RDVDPLLGFLPAKSGGAAAGGENEVAEFAFKD 86 Query: 95 SLQ---KRGIVEQCCTSICSLYQLENYCN 120 ++ KRGIVEQCC C+++ L+NYCN Sbjct: 87 QMEMMVKRGIVEQCCHKPCNIFDLQNYCN 115 >INS_ALLMI 51 INSULIN. Length = 51 Score = 82.7 bits (201), Expect = 1e-15 Identities = 42/79 (53%), Positives = 45/79 (56%), Gaps = 30/79 (37%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKRGI 101 NQ LCGSHLV+ALYLVCGERGFFY+P K GI Sbjct: 3 NQRLCGSHLVDALYLVCGERGFFYSP------------------------------KGGI 32 Query: 102 VEQCCTSICSLYQLENYCN 120 VEQCC + CSLYQLENYCN Sbjct: 33 VEQCCHNTCSLYQLENYCN 51 >AAD22742 113 INSULIN PRECURSOR. Length = 113 Score = 81.9 bits (199), Expect = 2e-15 Identities = 44/87 (50%), Positives = 55/87 (62%), Gaps = 11/87 (12%) Query: 43 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQG--EPTAHCCPWQPLALEGSLQ--- 97 QHLCGSHLV+ALYLVCG+RGFFY P RR+ + L G P A Q E + + Sbjct: 29 QHLCGSHLVDALYLVCGDRGFFYNP--RRDVDPLLGFLPPKAGGAVVQGGENEVTFKDQM 86 Query: 98 ----KRGIVEQCCTSICSLYQLENYCN 120 KRGIVE+CC C+++ L+NYCN Sbjct: 87 EMMVKRGIVEECCHKPCTIFDLQNYCN 113 >INS_LEPSP 52 INSULIN. Length = 52 Score = 81.1 bits (197), Expect = 3e-15 Identities = 40/79 (50%), Positives = 44/79 (55%), Gaps = 29/79 (36%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKRGI 101 NQHLCGSHLVEALYLVCGE+GFFY P K GI Sbjct: 3 NQHLCGSHLVEALYLVCGEKGFFYNP-----------------------------NKVGI 33 Query: 102 VEQCCTSICSLYQLENYCN 120 VEQCC C++Y+LENYCN Sbjct: 34 VEQCCHKPCTIYELENYCN 52 >INS_CYPCA 108 INSULIN PRECURSOR. Length = 108 Score = 80.0 bits (194), Expect = 6e-15 Identities = 42/84 (50%), Positives = 53/84 (63%), Gaps = 8/84 (9%) Query: 43 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQG---EPTAHCCPWQPLALEGS---L 96 QHLCGSHLV+ALYLVCG GFFY PK R+ + G +A A + + Sbjct: 27 QHLCGSHLVDALYLVCGPTGFFYNPK--RDVDPPLGFLPPKSAQETEVADFAFKDHAEVI 84 Query: 97 QKRGIVEQCCTSICSLYQLENYCN 120 +KRGIVEQCC CS+++L+NYCN Sbjct: 85 RKRGIVEQCCHKPCSIFELQNYCN 108 >INS_LOPPI 116 INSULIN PRECURSOR. Length = 116 Score = 79.6 bits (193), Expect = 8e-15 Identities = 42/90 (46%), Positives = 53/90 (58%), Gaps = 14/90 (15%) Query: 43 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQG---------EPTAHCCPWQPLALE 93 QHLCGSHLV+ALYLVCG+RGFFY PK R+ + L G A + Sbjct: 29 QHLCGSHLVDALYLVCGDRGFFYNPK--RDVDQLLGFLPPKSGGAAAAGADNEVAEFAFK 86 Query: 94 GSLQ---KRGIVEQCCTSICSLYQLENYCN 120 ++ KRGIVEQCC C+++ L+NYCN Sbjct: 87 DQMEMMVKRGIVEQCCHRPCNIFDLQNYCN 116 >CAA08766 59 INSULIN (FRAGMENT). Length = 59 Score = 79.2 bits (192), Expect = 1e-14 Identities = 35/35 (100%), Positives = 35/35 (100%) Query: 40 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 74 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59 >INS_HYDCO 59 INSULIN. Length = 59 Score = 79.2 bits (192), Expect = 1e-14 Identities = 41/78 (52%), Positives = 44/78 (55%), Gaps = 22/78 (28%) Query: 43 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKRGIV 102 Q LCGSHLV+ALY VCGERGFFY+PK RE E L GIV Sbjct: 4 QRLCGSHLVDALYFVCGERGFFYSPKPIRELEPL----------------------LGIV 41 Query: 103 EQCCTSICSLYQLENYCN 120 EQCC + CSL LE YCN Sbjct: 42 EQCCHNTCSLANLEGYCN 59 >INS_TORMA 70 INSULIN PRECURSOR (FRAGMENTS). Length = 70 Score = 77.3 bits (187), Expect = 4e-14 Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 11/79 (13%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGEPTAHCCPWQPLALEGSLQKRGI 101 +QHLCGSHLVEALY VCG +GF+Y PK + L G G + GI Sbjct: 3 SQHLCGSHLVEALYFVCGPKGFYYLPKAXXFVDSLAGYSKHQ---------NGGIS--GI 51 Query: 102 VEQCCTSICSLYQLENYCN 120 VE CC + CSL+ LE YCN Sbjct: 52 VEHCCHNTCSLFDLEGYCN 70 >INS_MYXGL 115 INSULIN PRECURSOR. Length = 115 Score = 72.6 bits (175), Expect = 1e-12 Identities = 41/91 (45%), Positives = 51/91 (55%), Gaps = 20/91 (21%) Query: 44 HLCGSHLVEALYLVCGERGFFYTP-KTRRE------------AEDLQGEPTAHCCPWQPL 90 HLCG LV ALY+ CG RGFFY P K +R+ AED + + + + Sbjct: 31 HLCGKDLVNALYIACGVRGFFYDPTKMKRDTGALAAFLPLAYAEDNESQDD------ESI 84 Query: 91 ALEGSLQ-KRGIVEQCCTSICSLYQLENYCN 120 + L+ KRGIVEQCC CS+Y LENYCN Sbjct: 85 GINEVLKSKRGIVEQCCHKRCSIYDLENYCN 115 >O42485 74 PROINSULIN (FRAGMENT). Length = 74 Score = 65.6 bits (157), Expect = 1e-10 Identities = 37/75 (49%), Positives = 42/75 (55%), Gaps = 10/75 (13%) Query: 55 YLVCGERGFFYTPKTRREAEDLQG----EPTAHC-----CPWQPLALEGSLQKRGIVEQC 105 Y VCGERGFFY+PK R+ L EP P++ L GS KRGIVEQC Sbjct: 1 YFVCGERGFFYSPKQIRDVGPLSAFRDLEPPLDTEMEDRFPYRQ-QLAGSKMKRGIVEQC 59 Query: 106 CTSICSLYQLENYCN 120 C + CSL LE YCN Sbjct: 60 CHNTCSLVNLEGYCN 74 >G1699408 30 INSULIN B CHAIN. Length = 30 Score = 64.4 bits (154), Expect = 3e-10 Identities = 27/28 (96%), Positives = 28/28 (99%) Query: 42 NQHLCGSHLVEALYLVCGERGFFYTPKT 69 NQHLCGSHLVEALYLVCGERGFFY+PKT Sbjct: 3 NQHLCGSHLVEALYLVCGERGFFYSPKT 30 Database: sptrembl: Non-redundant SWISSPROT + TREMBL database (from SWISS-PROT Rel. 38 + TrEMBL Rel. 11 + TrEMBL_NEW: Last Updated: Oct 25, 1999) Posted date: Nov 8, 1999 9:06 AM Number of letters in database: 113,768,070 Number of sequences in database: 361,918 Lambda K H 0.325 0.140 0.486 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23143049 Number of Sequences: 361918 Number of extensions: 701617 Number of successful extensions: 1883 Number of sequences better than 10: 197 Number of HSP's better than 10.0 without gapping: 184 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 1538 Number of HSP's gapped (non-prelim): 226 length of query: 120 length of database: 113768070 effective HSP length: 42 effective length of query: 78 effective length of database: 98567514 effective search space: 7688266092 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.6 bits) S2: 65 (29.7 bits)