Score E
Sequences producing significant alignments: (bits) Value
gi|4557671|ref|NP_000198.1| proinsulin precursor [Homo sapi... 167 2e-41
gi|266377|sp|P30410|INS_PANTR INSULIN PRECURSOR >gi|283944|... 167 2e-41
gi|208668|gb|AAA72172.1| (J02547) synthetic preproinsulin [... 167 2e-41
gi|266362|sp|P30407|INS_CERAE INSULIN PRECURSOR >gi|283935|... 166 4e-41
gi|266373|sp|P30406|INS_MACFA INSULIN PRECURSOR >gi|86627|p... 165 5e-41
gi|58103|emb|CAA23424.1| (V00082) reading frame proinsulin ... 160 2e-39
gi|223965|prf||1006230A insulin,pro- [Macaca mulatta] 158 7e-39
gi|307072|gb|AAA59179.1| (L15440) insulin [Homo sapiens] 156 3e-38
gi|124575|sp|P01321|INS_CANFA INSULIN PRECURSOR >gi|69312|p... 151 1e-36
gi|9506817|ref|NP_062003.1| insulin 2 [Rattus norvegicus] >... 146 4e-35
gi|124588|sp|P01313|INS_CRILO INSULIN PRECURSOR >gi|2137094... 145 7e-35
gi|6680463|ref|NP_032413.1| insulin II [Mus musculus] >gi|1... 144 1e-34
gi|9506815|ref|NP_062002.1| insulin [Rattus norvegicus] >gi... 143 2e-34
gi|124553|sp|P10604|INS_AOTTR INSULIN PRECURSOR >gi|104987|... 143 4e-34
gi|2497407|sp|Q62587|INS_PSAOB INSULIN PRECURSOR >gi|137028... 140 3e-33
gi|229392|prf||720460B insulin 2,pro [Rattus norvegicus] 140 3e-33
gi|229391|prf||720460A insulin 1,pro [Rattus norvegicus] 138 8e-33
gi|6680461|ref|NP_032412.1| insulin I [Mus musculus] >gi|12... 134 1e-31
gi|1352467|sp|P01311|INS_RABIT INSULIN PRECURSOR >gi|108315... 134 2e-31
gi|12841054|dbj|BAB25058.1| (AK007482) putative [Mus musculus] 134 2e-31
gi|14906249|gb|AAK72558.1| (AY038604) insulin [Spermophilus... 131 1e-30
gi|3885494|gb|AAC77920.1| (AF064555) preproinsulin [Sus scr... 119 3e-27
gi|124615|sp|P21563|INS_RODSP INSULIN PRECURSOR >gi|102414|... 119 6e-27
gi|12643972|sp|P01315|INS_PIG INSULIN PRECURSOR 117 3e-26
gi|69306|pir||IPPG insulin precursor - pig 114 1e-25
gi|124616|sp|P01310|INS_HORSE INSULIN PRECURSOR >gi|69301|p... 112 8e-25
gi|124564|sp|P01317|INS_BOVIN INSULIN PRECURSOR >gi|1070561... 107 2e-23
gi|387059|gb|AAA37041.1| (K02233) insulin [Cavia porcellus] 105 7e-23
gi|1708500|sp|P01318|INS_SHEEP INSULIN PRECURSOR >gi|405982... 105 9e-23
gi|124581|sp|P01329|INS_CAVPO INSULIN PRECURSOR >gi|69322|p... 104 1e-22
gi|124651|sp|P17715|INS_OCTDE INSULIN PRECURSOR >gi|538567|... 102 7e-22
gi|1708499|sp|P51463|INS_SELRF INSULIN PRECURSOR >gi|214796... 98 1e-20
gi|124587|sp|P01332|INS_CHICK INSULIN PRECURSOR >gi|69325|p... 98 2e-20
gi|7546360|pdb|1EFE|A Chain A, An Active Mini-Proinsulin, M2pi 97 2e-20
gi|124526|sp|P12707|INS2_XENLA INSULIN 2 PRECURSOR >gi|6933... 96 5e-20
gi|124513|sp|P12706|INS1_XENLA INSULIN 1 PRECURSOR >gi|6933... 94 2e-19
gi|9408409|gb|AAF87285.1|AF227187_1 (AF227187) preproinsuli... 91 2e-18
gi|11275220|pir||PC7082 epidermal growth factor/single chai... 90 3e-18
gi|13517227|gb|AAK28713.1| (AF199589) preproinsulin [Osteog... 88 1e-17
gi|3127060|gb|AAC78289.1| (AF050524) proinsulin-like protei... 88 1e-17
gi|124547|sp|P01333|INS_ANAPL INSULIN PRECURSOR >gi|69328|p... 88 2e-17
gi|13517225|gb|AAK28712.1| (AF199588) preproinsulin [Pantod... 87 3e-17
gi|69309|pir||INSH insulin precursor - sheep 86 7e-17
gi|69317|pir||INMSSP insulin - Egyptian spiny mouse (tentat... 84 2e-16
gi|14161273|gb|AAK54684.1| (AF282408) preproinsulin [Hiodon... 84 3e-16
gi|13517221|gb|AAK28710.1| (AF199586) preproinsulin [Chital... 83 3e-16
gi|69316|pir||INHY insulin - hamster 81 1e-15
gi|69303|pir||INWHP insulin - sperm whale >gi|69304|pir||IN... 81 2e-15
gi|4558198|pdb|1ZEI|A Chain A, Cross-Linked B28 Asp Insulin... 80 3e-15
gi|494923|pdb|6INS|E Chain E, Insulin (Peptide-Linked, 29b ... 80 3e-15
gi|9973534|sp|Q9W7R2|INS_VERMO INSULIN PRECURSOR >gi|538126... 80 4e-15
gi|69307|pir||INEL insulin - elephant 80 4e-15
gi|124657|sp|P04667|INS_ONCKE INSULIN PRECURSOR >gi|69342|p... 79 7e-15
gi|13517223|gb|AAK28711.1| (AF199587) preproinsulin [Gnatho... 79 7e-15
gi|12644021|sp|P81025|INS_ORENI INSULIN PRECURSOR >gi|45587... 79 7e-15
gi|3776078|emb|CAA08766.1| (AJ009655) insulin [Homo sapiens] 79 8e-15
gi|213445|gb|AAA49414.1| (J00936) preproinsulin [Oncorhynch... 79 1e-14
gi|7438602|pir||A59151 insulin precursor - jack bean (fragm... 79 1e-14
gi|13517219|gb|AAK28709.1| (AF199585) preproinsulin [Catost... 78 2e-14
gi|538566|pir||INMKSQ insulin - common squirrel monkey 78 2e-14
gi|124594|sp|P01335|INS_CYPCA INSULIN PRECURSOR >gi|69334|p... 77 2e-14
gi|124638|sp|P01341|INS_LOPPI INSULIN PRECURSOR >gi|69346|p... 77 2e-14
gi|69320|pir||INCB insulin - Chinchilla brevicaudata 77 2e-14
gi|69305|pir||INWH1S insulin - sei whale 77 2e-14
gi|12053668|emb|CAC20109.1| (AJ237750) insulin [Danio rerio] 77 2e-14
gi|9973509|sp|O73727|INS_BRARE INSULIN PRECURSOR >gi|293570... 77 3e-14
gi|69311|pir||INCMA insulin - Arabian camel (tentative sequ... 77 3e-14
gi|13991923|gb|AAK51558.1|AF373021_1 (AF373021) preproinsul... 77 3e-14
gi|69313|pir||INCT insulin - cat 77 4e-14
gi|12643999|sp|P13190|INS_CALMI INSULIN PRECURSOR 77 4e-14
gi|69310|pir||INGT insulin - goat 77 4e-14
gi|64362|emb|CAA24983.1| (X00148) preproinsulin [Oncorhynch... 76 6e-14
gi|2981815|pdb|1SJU| Mini-Proinsulin, Single Chain Insul... 75 9e-14
gi|13517217|gb|AAK28708.1| (AF199584) preproinsulin [Amblop... 75 1e-13
gi|86565|pir||JQ0362 insulin - North American opossum 75 1e-13
gi|69344|pir||INBN2 insulin - skipjack tuna (tentative sequ... 75 2e-13
gi|7438595|pir||S44470 insulin I2 - North American paddlefi... 72 8e-13
gi|69329|pir||INGS insulin - goose 72 1e-12
gi|69321|pir||INPQ insulin - crested porcupine 72 1e-12
gi|7438594|pir||S44469 insulin I1 - North American paddlefi... 72 1e-12
gi|69326|pir||INTK insulin - turkey (tentative sequence) >g... 71 2e-12
gi|470321|gb|AAA17540.1| (M61153) insulin [Oryctolagus cuni... 70 3e-12
gi|124650|sp|P01342|INS_MYXGL INSULIN PRECURSOR >gi|69353|p... 69 6e-12
gi|7438596|pir||S63590 insulin - duckbill platypus 68 1e-11
gi|7438597|pir||S61361 insulin - Amphiuma tridactylum 68 1e-11
gi|229541|prf||753014A insulin [Cricetinae gen. sp.] 68 2e-11
gi|63530|emb|CAA23707.1| (V00416) part of reading frame [Ga... 68 2e-11
gi|69345|pir||INGXA insulin - alligator gar 67 3e-11
gi|69349|pir||INFI insulin precursor - spotted ratfish (fra... 67 3e-11
gi|69330|pir||INAQ insulin - American alligator 67 3e-11
gi|2143547|pir||I49419 insulin II precursor - western wild ... 67 4e-11
gi|85933|pir||JQ0359 insulin - colubrid snake (Zaocys dhumn... 66 7e-11
gi|69331|pir||INRS insulin - western diamondback rattlesnake 65 9e-11
gi|124535|sp||INS_ACOCA_1 [Segment 1 of 2] INSULIN 65 1e-10
gi|929915|emb|CAA24707.1| (V01461) insulin C chain [synthet... 65 1e-10
gi|69354|pir||INLMS insulin - sea lamprey 65 2e-10
gi|69343|pir||INFLE insulin - European flounder 65 2e-10
gi|208664|gb|AAA72171.1| (J02545) insulin B chain [syntheti... 64 2e-10
gi|69351|pir||INDF insulin - spiny dogfish (tentative seque... 64 2e-10
gi|225446|prf||1303322A insulin [Oncorhynchus keta] 64 2e-10
Alignments
>gi|4557671|ref|NP_000198.1| proinsulin precursor [Homo sapiens]
gi|14773144|ref|XP_028180.1| proinsulin precursor [Homo sapiens]
gi|124617|sp|P01308|INS_HUMAN INSULIN PRECURSOR
gi|69300|pir||IPHU insulin precursor - human
gi|386828|gb|AAA59172.1| (J00268) insulin [Homo sapiens]
gi|386829|gb|AAA59173.1| (M10039) insulin [Homo sapiens]
gi|394766|emb|CAA49913.1| (X70508) pre-proinsulin [Homo sapiens]
gi|758088|emb|CAA23828.1| (V00565) preproinsulin [Homo sapiens]
gi|13528924|gb|AAH05255.1|AAH05255 (BC005255) insulin [Homo sapiens]
gi|223160|prf||0601246A insulin,prepro [Homo sapiens]
Length = 110
Score = 167 bits (423), Expect = 2e-41
Identities = 86/86 (100%), Positives = 86/86 (100%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|266377|sp|P30410|INS_PANTR INSULIN PRECURSOR
gi|283944|pir||A42179 insulin precursor - chimpanzee
gi|38252|emb|CAA43403.1| (X61089) Preproinsulin [Pan troglodytes]
Length = 110
Score = 167 bits (423), Expect = 2e-41
Identities = 86/86 (100%), Positives = 86/86 (100%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|208668|gb|AAA72172.1| (J02547) synthetic preproinsulin [synthetic construct]
Length = 114
Score = 167 bits (422), Expect = 2e-41
Identities = 86/86 (100%), Positives = 86/86 (100%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG
Sbjct: 29 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 88
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 89 SLQKRGIVEQCCTSICSLYQLENYCN 114
>gi|266362|sp|P30407|INS_CERAE INSULIN PRECURSOR
gi|283935|pir||B42179 insulin precursor - green monkey
gi|22809|emb|CAA43405.1| (X61092) Preproinsulin [Cercopithecus aethiops]
Length = 110
Score = 166 bits (419), Expect = 4e-41
Identities = 85/86 (98%), Positives = 85/86 (98%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEG
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEG 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|266373|sp|P30406|INS_MACFA INSULIN PRECURSOR
gi|86627|pir||JQ0178 insulin precursor - crab-eating macaque
gi|342122|gb|AAA36849.1| (J00336) preproinsulin [Macaca fascicularis]
Length = 110
Score = 165 bits (418), Expect = 5e-41
Identities = 85/86 (98%), Positives = 85/86 (98%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEG
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEG 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|58103|emb|CAA23424.1| (V00082) reading frame proinsulin [synthetic construct]
gi|208670|gb|AAA72531.1| (M12913) proinsulin [synthetic construct]
Length = 87
Score = 160 bits (405), Expect = 2e-39
Identities = 86/86 (100%), Positives = 86/86 (100%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG
Sbjct: 2 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 61
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 62 SLQKRGIVEQCCTSICSLYQLENYCN 87
>gi|223965|prf||1006230A insulin,pro- [Macaca mulatta]
Length = 86
Score = 158 bits (400), Expect = 7e-39
Identities = 85/86 (98%), Positives = 85/86 (98%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEG
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEG 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 SLQKRGIVEQCCTSICSLYQLENYCN 86
>gi|307072|gb|AAA59179.1| (L15440) insulin [Homo sapiens]
Length = 107
Score = 156 bits (394), Expect = 3e-38
Identities = 83/86 (96%), Positives = 83/86 (96%), Gaps = 3/86 (3%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE VGQVELGGGPGAGSLQPLALEG
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE---VGQVELGGGPGAGSLQPLALEG 81
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 82 SLQKRGIVEQCCTSICSLYQLENYCN 107
>gi|124575|sp|P01321|INS_CANFA INSULIN PRECURSOR
gi|69312|pir||IPDG insulin precursor - dog
gi|995|emb|CAA23475.1| (V00179) preproinsulin [Canis sp.]
Length = 110
Score = 151 bits (382), Expect = 1e-36
Identities = 77/86 (89%), Positives = 78/86 (90%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE EDLQV VEL G PG G LQPLALEG
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEDLQVRDVELAGAPGEGGLQPLALEG 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+LQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 85 ALQKRGIVEQCCTSICSLYQLENYCN 110
>gi|9506817|ref|NP_062003.1| insulin 2 [Rattus norvegicus]
gi|124520|sp|P01323|INS2_RAT INSULIN 2 PRECURSOR
gi|69315|pir||IPRT2 insulin 2 precursor - rat
gi|56490|emb|CAA24560.1| (V01243) preproinsulin [Rattus norvegicus]
gi|204952|gb|AAA41440.1| (M25585) insulin 2 [Rattus norvegicus]
gi|204959|gb|AAA41443.1| (J00748) preproinsulin II [Rattus norvegicus]
Length = 110
Score = 146 bits (368), Expect = 4e-35
Identities = 73/86 (84%), Positives = 77/86 (88%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED QV Q+ELGGGPGAG LQ LALE
Sbjct: 25 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAGDLQTLALEV 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 85 ARQKRGIVDQCCTSICSLYQLENYCN 110
>gi|124588|sp|P01313|INS_CRILO INSULIN PRECURSOR
gi|2137094|pir||I48166 insulin precursor - golden hamster
gi|305360|gb|AAA37089.1| (M26328) preproinsulin [Mesocricetus auratus]
Length = 110
Score = 145 bits (365), Expect = 7e-35
Identities = 73/86 (84%), Positives = 77/86 (88%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK+RR ED QV Q+ELGGGPGA LQ LALE
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKSRRGVEDPQVAQLELGGGPGADDLQTLALEV 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 85 AQQKRGIVDQCCTSICSLYQLENYCN 110
>gi|6680463|ref|NP_032413.1| insulin II [Mus musculus]
gi|124519|sp|P01326|INS2_MOUSE INSULIN 2 PRECURSOR
gi|625280|pir||INMS2 insulin 2 precursor - mouse
gi|52715|emb|CAA28433.1| (X04724) preproinsulin II [Mus musculus]
gi|12841261|dbj|BAB25135.1| (AK007612) putative [Mus musculus]
gi|744259|prf||2014276B insulin [Mus musculus]
Length = 110
Score = 144 bits (364), Expect = 1e-34
Identities = 73/86 (84%), Positives = 77/86 (88%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED QV Q+ELGGGPGAG LQ LALE
Sbjct: 25 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAGDLQTLALEV 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 85 AQQKRGIVDQCCTSICSLYQLENYCN 110
>gi|9506815|ref|NP_062002.1| insulin [Rattus norvegicus]
gi|124512|sp|P01322|INS1_RAT INSULIN 1 PRECURSOR
gi|69314|pir||IPRT1 insulin 1 precursor - rat
gi|56488|emb|CAA24559.1| (V01242) insulin I [Rattus norvegicus]
gi|204948|gb|AAA41439.1| (M25584) insulin 1 [Rattus norvegicus]
gi|204957|gb|AAA41442.1| (J00747) preproinsulin I [Rattus norvegicus]
Length = 110
Score = 143 bits (361), Expect = 2e-34
Identities = 72/86 (83%), Positives = 76/86 (87%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED QV Q+ELGGGP AG LQ LALE
Sbjct: 25 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVPQLELGGGPEAGDLQTLALEV 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 85 ARQKRGIVDQCCTSICSLYQLENYCN 110
>gi|124553|sp|P10604|INS_AOTTR INSULIN PRECURSOR
gi|104987|pir||A39883 insulin precursor - douroucouli
gi|176556|gb|AAA35374.1| (J02989) preproinsulin [Aotus trivirgatus]
Length = 108
Score = 143 bits (360), Expect = 4e-34
Identities = 73/86 (84%), Positives = 77/86 (88%), Gaps = 2/86 (2%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCG HLVEALYLVCGERGFFY PKTRREAEDLQVGQVELGGG GSL P LEG
Sbjct: 25 FVNQHLCGPHLVEALYLVCGERGFFYAPKTRREAEDLQVGQVELGGGSITGSLPP--LEG 82
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+QKRG+V+QCCTSICSLYQL+NYCN
Sbjct: 83 PMQKRGVVDQCCTSICSLYQLQNYCN 108
>gi|2497407|sp|Q62587|INS_PSAOB INSULIN PRECURSOR
gi|1370283|emb|CAA66897.1| (X98241) preproinsulin [Psammomys obesus]
Length = 110
Score = 140 bits (352), Expect = 3e-33
Identities = 70/86 (81%), Positives = 75/86 (86%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RR +D Q+ Q+ELGG PGAG L+ LALE
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKFRRGVDDPQMPQLELGGSPGAGDLRALALEV 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIVEQCCT ICSLYQLENYCN
Sbjct: 85 ARQKRGIVEQCCTGICSLYQLENYCN 110
>gi|229392|prf||720460B insulin 2,pro [Rattus norvegicus]
Length = 86
Score = 140 bits (352), Expect = 3e-33
Identities = 73/86 (84%), Positives = 77/86 (88%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED QV Q+ELGGGPGAG LQ LALE
Sbjct: 1 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVPQLELGGGPGAGDLQTLALEV 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 ARQKRGIVDQCCTSICSLYQLENYCN 86
>gi|229391|prf||720460A insulin 1,pro [Rattus norvegicus]
Length = 86
Score = 138 bits (348), Expect = 8e-33
Identities = 72/86 (83%), Positives = 76/86 (87%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED QV Q+ELGGGP AG LQ LALE
Sbjct: 1 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVPQLELGGGPEAGDLQTLALEV 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 ARQKRGIVDQCCTSICSLYQLENYCN 86
>gi|6680461|ref|NP_032412.1| insulin I [Mus musculus]
gi|124511|sp|P01325|INS1_MOUSE INSULIN 1 PRECURSOR
gi|625279|pir||INMS1 insulin 1 precursor - mouse
gi|52713|emb|CAA28434.1| (X04725) preproinsulin I (AA 1-108) [Mus musculus]
gi|12840833|dbj|BAB24974.1| (AK007345) putative [Mus musculus]
gi|12842500|dbj|BAB25628.1| (AK008358) putative [Mus musculus]
gi|744258|prf||2014276A insulin [Mus musculus]
Length = 108
Score = 134 bits (338), Expect = 1e-31
Identities = 70/86 (81%), Positives = 74/86 (85%), Gaps = 2/86 (2%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED QV Q+ELGG P G LQ LALE
Sbjct: 25 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVEQLELGGSP--GDLQTLALEV 82
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 83 ARQKRGIVDQCCTSICSLYQLENYCN 108
>gi|1352467|sp|P01311|INS_RABIT INSULIN PRECURSOR
gi|1083159|pir||A53438 insulin precursor - rabbit
gi|7428584|pir||INRB insulin precursor - rabbit
gi|467971|gb|AAA19033.1| (U03610) insulin [Oryctolagus cuniculus]
Length = 110
Score = 134 bits (336), Expect = 2e-31
Identities = 78/86 (90%), Positives = 81/86 (93%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK+RRE E+LQVGQ ELGGGPGAG LQP ALE
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKSRREVEELQVGQAELGGGPGAGGLQPSALEL 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+LQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 85 ALQKRGIVEQCCTSICSLYQLENYCN 110
>gi|12841054|dbj|BAB25058.1| (AK007482) putative [Mus musculus]
Length = 108
Score = 134 bits (336), Expect = 2e-31
Identities = 69/86 (80%), Positives = 74/86 (85%), Gaps = 2/86 (2%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCG HLV+ALYLVCGERGFFYTPK+RRE ED QV Q+ELGG P G LQ LALE
Sbjct: 25 FVKQHLCGPHLVKALYLVCGERGFFYTPKSRREVEDPQVEQLELGGSP--GDLQTLALEV 82
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 83 ARQKRGIVDQCCTSICSLYQLENYCN 108
>gi|14906249|gb|AAK72558.1| (AY038604) insulin [Spermophilus tridecemlineatus]
Length = 110
Score = 131 bits (329), Expect = 1e-30
Identities = 77/86 (89%), Positives = 80/86 (92%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK+RRE E+ Q GQVELGGGPGAG QPLALE
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKSRREVEEQQGGQVELGGGPGAGLPQPLALEM 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+LQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 85 ALQKRGIVEQCCTSICSLYQLENYCN 110
>gi|3885494|gb|AAC77920.1| (AF064555) preproinsulin [Sus scrofa]
Length = 127
Score = 119 bits (299), Expect = 3e-27
Identities = 72/86 (83%), Positives = 73/86 (84%), Gaps = 2/86 (2%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q G VE G G G LQ LALEG
Sbjct: 44 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVE--LGGGLGGLQALALEG 101
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
QKRGIVEQCCTSICSLYQLENYCN
Sbjct: 102 PPQKRGIVEQCCTSICSLYQLENYCN 127
>gi|124615|sp|P21563|INS_RODSP INSULIN PRECURSOR
gi|102414|pir||S09278 insulin precursor - Geodia cydonium
Length = 108
Score = 119 bits (298), Expect = 6e-27
Identities = 69/87 (79%), Positives = 73/87 (83%), Gaps = 3/87 (3%)
Query: 25 FVNQHLCGSHLVEALY-LVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALE 83
FVNQHLCGSHLVEALY LVCGERGFFYTP +RRE ED QVGQVELG GPGAGS Q LALE
Sbjct: 24 FVNQHLCGSHLVEALYILVCGERGFFYTPMSRREVEDPQVGQVELGAGPGAGSEQTLALE 83
Query: 84 GSLQKRGIVEQCCTSICSLYQLENYCN 110
+ Q R IV+QC + ICSLYQ ENYCN
Sbjct: 84 VARQAR-IVQQCTSGICSLYQ-ENYCN 108
>gi|12643972|sp|P01315|INS_PIG INSULIN PRECURSOR
Length = 108
Score = 117 bits (292), Expect = 3e-26
Identities = 72/86 (83%), Positives = 73/86 (84%), Gaps = 2/86 (2%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q G VE G G G LQ LALEG
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVE--LGGGLGGLQALALEG 82
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
QKRGIVEQCCTSICSLYQLENYCN
Sbjct: 83 PPQKRGIVEQCCTSICSLYQLENYCN 108
>gi|69306|pir||IPPG insulin precursor - pig
Length = 84
Score = 114 bits (285), Expect = 1e-25
Identities = 72/86 (83%), Positives = 73/86 (84%), Gaps = 2/86 (2%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q G VE G G G LQ LALEG
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVE--LGGGLGGLQALALEG 58
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
QKRGIVEQCCTSICSLYQLENYCN
Sbjct: 59 PPQKRGIVEQCCTSICSLYQLENYCN 84
>gi|124616|sp|P01310|INS_HORSE INSULIN PRECURSOR
gi|69301|pir||IPHO insulin precursor - horse
Length = 86
Score = 112 bits (279), Expect = 8e-25
Identities = 73/86 (84%), Positives = 74/86 (85%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK EAED QVG+VELGGGPG G LQPLAL G
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKAXXEAEDPQVGEVELGGGPGLGGLQPLALAG 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
Q GIVEQCCT ICSLYQLENYCN
Sbjct: 61 PQQXXGIVEQCCTGICSLYQLENYCN 86
>gi|124564|sp|P01317|INS_BOVIN INSULIN PRECURSOR
gi|1070561|pir||IPBO insulin precursor - bovine
gi|163579|gb|AAA30722.1| (M54979) preproinsulin [Bos taurus]
Length = 105
Score = 107 bits (266), Expect = 2e-23
Identities = 67/86 (77%), Positives = 70/86 (80%), Gaps = 5/86 (5%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E QVG +EL GGPGAG L+
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAGGLEGPP--- 81
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
QKRGIVEQCC S+CSLYQLENYCN
Sbjct: 82 --QKRGIVEQCCASVCSLYQLENYCN 105
>gi|387059|gb|AAA37041.1| (K02233) insulin [Cavia porcellus]
Length = 110
Score = 105 bits (262), Expect = 7e-23
Identities = 59/86 (68%), Positives = 69/86 (79%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV++HLCGS+LVE LY VC + GFFY PK RRE ED QV Q ELG G GAG LQPLALE
Sbjct: 25 FVSRHLCGSNLVETLYSVCQDDGFFYIPKDRRELEDPQVEQTELGMGLGAGGLQPLALEM 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+LQKRGIV+QCCT C+ +QL++YCN
Sbjct: 85 ALQKRGIVDQCCTGTCTRHQLQSYCN 110
>gi|1708500|sp|P01318|INS_SHEEP INSULIN PRECURSOR
gi|405982|gb|AAB60625.1| (U00668) insulin [Ovis aries]
Length = 105
Score = 105 bits (261), Expect = 9e-23
Identities = 66/86 (76%), Positives = 69/86 (79%), Gaps = 5/86 (5%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E QVG +EL GGPGAG L+
Sbjct: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAGGLEGPP--- 81
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
QKRGIVEQCC +CSLYQLENYCN
Sbjct: 82 --QKRGIVEQCCAGVCSLYQLENYCN 105
>gi|124581|sp|P01329|INS_CAVPO INSULIN PRECURSOR
gi|69322|pir||IPGP insulin precursor - guinea pig
gi|305337|gb|AAA37042.1| (M11713) preproinsulin [Cavia porcellus]
Length = 110
Score = 104 bits (260), Expect = 1e-22
Identities = 59/86 (68%), Positives = 69/86 (79%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV++HLCGS+LVE LY VC + GFFY PK RRE ED QV Q ELG G GAG LQPLALE
Sbjct: 25 FVSRHLCGSNLVETLYSVCQDDGFFYIPKDRRELEDPQVEQTELGMGLGAGGLQPLALEM 84
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+LQKRGIV+QCCT C+ +QL++YCN
Sbjct: 85 ALQKRGIVDQCCTGTCTRHQLQSYCN 110
>gi|124651|sp|P17715|INS_OCTDE INSULIN PRECURSOR
gi|538567|pir||IPRTDU insulin precursor - degu
gi|202472|gb|AAA40590.1| (M57671) insulin [Octodon degus]
Length = 109
Score = 102 bits (254), Expect = 7e-22
Identities = 56/86 (65%), Positives = 64/86 (74%), Gaps = 3/86 (3%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
+ +QHLCGS+LVEALY+ CG G FY P RRE EDLQV Q EL G AG LQP ALE
Sbjct: 25 YSSQHLCGSNLVEALYMTCGRSG-FYRPHDRRELEDLQVEQAEL--GLEAGGLQPSALEM 81
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
LQKRGIV+QCC +IC+ QL+NYCN
Sbjct: 82 ILQKRGIVDQCCNNICTFNQLQNYCN 107
>gi|1708499|sp|P51463|INS_SELRF INSULIN PRECURSOR
gi|2147962|pir||I51221 insulin precursor - Selaphorus rufus (fragment)
gi|451262|gb|AAC64211.1| (S66612) preproinsulin [Selasphorus rufus]
Length = 103
Score = 98.2 bits (243), Expect = 1e-20
Identities = 57/88 (64%), Positives = 61/88 (68%), Gaps = 9/88 (10%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL--- 82
VNQHLCGSHLVEALYLVCGERGFFY+PK RR+AE L GP G + L
Sbjct: 22 VNQHLCGSHLVEALYLVCGERGFFYSPKARRDAEH------PLVNGPLHGEVGDLPFQQE 75
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110
E KRGIVEQCC + CSLYQLENYCN
Sbjct: 76 EFEKVKRGIVEQCCHNTCSLYQLENYCN 103
>gi|124587|sp|P01332|INS_CHICK INSULIN PRECURSOR
gi|69325|pir||IPCH insulin precursor - chicken
gi|212212|gb|AAA48925.1| (J00874) preproinsulin (second expressed [Gallus gallus]
gi|853836|emb|CAA41738.1| (X58993) preproinsulin [Gallus gallus]
Length = 107
Score = 97.8 bits (242), Expect = 2e-20
Identities = 55/84 (65%), Positives = 58/84 (68%), Gaps = 3/84 (3%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
NQHLCGSHLVEALYLVCGERGFFY+PK RR+ E V G AG L E
Sbjct: 27 NQHLCGSHLVEALYLVCGERGFFYSPKARRDVEQPLVSSPLRG---EAGVLPFQQEEYEK 83
Query: 87 QKRGIVEQCCTSICSLYQLENYCN 110
KRGIVEQCC + CSLYQLENYCN
Sbjct: 84 VKRGIVEQCCHNTCSLYQLENYCN 107
>gi|7546360|pdb|1EFE|A Chain A, An Active Mini-Proinsulin, M2pi
Length = 60
Score = 97.4 bits (241), Expect = 2e-20
Identities = 56/86 (65%), Positives = 57/86 (66%), Gaps = 26/86 (30%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRR D+
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRRYPGDV----------------------- 37
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
KRGIVEQCCTSICSLYQLENYCN
Sbjct: 38 ---KRGIVEQCCTSICSLYQLENYCN 60
>gi|124526|sp|P12707|INS2_XENLA INSULIN 2 PRECURSOR
gi|69333|pir||IPXL2 insulin II precursor - African clawed frog
gi|214535|gb|AAA49887.1| (M24442) preproinsulin II [Xenopus laevis]
Length = 106
Score = 95.9 bits (237), Expect = 5e-20
Identities = 53/87 (60%), Positives = 58/87 (65%), Gaps = 9/87 (10%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL---E 83
NQHLCGSHLVEALYLVCG+RGFFY PK +R+ E QV GP L + E
Sbjct: 26 NQHLCGSHLVEALYLVCGDRGFFYYPKIKRDIEQAQV------NGPQDNELDGMQFQPQE 79
Query: 84 GSLQKRGIVEQCCTSICSLYQLENYCN 110
KRGIVEQCC S CSL+QLENYCN
Sbjct: 80 YQKMKRGIVEQCCHSTCSLFQLENYCN 106
>gi|124513|sp|P12706|INS1_XENLA INSULIN 1 PRECURSOR
gi|69332|pir||IPXL1 insulin I precursor - African clawed frog
gi|214537|gb|AAA49888.1| (M24443) preproinsulin I [Xenopus laevis]
Length = 106
Score = 94.4 bits (233), Expect = 2e-19
Identities = 53/88 (60%), Positives = 59/88 (66%), Gaps = 9/88 (10%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL--- 82
VNQHLCGSHLVEALYLVCG+RGFFY PK +R+ E V GP L + L
Sbjct: 25 VNQHLCGSHLVEALYLVCGDRGFFYYPKVKRDMEQALV------SGPQDNELDGMQLQPQ 78
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110
E KRGIVEQCC S CSL+QLE+YCN
Sbjct: 79 EYQKMKRGIVEQCCHSTCSLFQLESYCN 106
>gi|9408409|gb|AAF87285.1|AF227187_1 (AF227187) preproinsulin [Rana pipiens]
Length = 106
Score = 90.9 bits (224), Expect = 2e-18
Identities = 47/86 (54%), Positives = 60/86 (69%), Gaps = 3/86 (3%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
F NQ+LCGSHLVEALY+VCG+RGFFY+P++RR+ E V ++ G +Q +
Sbjct: 24 FDNQYLCGSHLVEALYMVCGDRGFFYSPRSRRDLEQPLVNGLQ---GSELDEMQVQSQAF 80
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+K GIVEQCC + CSLY LENYCN
Sbjct: 81 QKRKPGIVEQCCHNTCSLYDLENYCN 106
>gi|11275220|pir||PC7082 epidermal growth factor/single chain insulin fusion protein -
Bacillus brevis (fragment)
Length = 96
Score = 90.1 bits (222), Expect = 3e-18
Identities = 50/86 (58%), Positives = 50/86 (58%), Gaps = 36/86 (41%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK
Sbjct: 47 FVNQHLCGSHLVEALYLVCGERGFFYTPK------------------------------- 75
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCCTSICSLYQLENYCN
Sbjct: 76 -----GIVEQCCTSICSLYQLENYCN 96
>gi|13517227|gb|AAK28713.1| (AF199589) preproinsulin [Osteoglossum bicirrhosum]
Length = 111
Score = 88.2 bits (217), Expect = 1e-17
Identities = 46/85 (54%), Positives = 58/85 (68%), Gaps = 1/85 (1%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+Q LCGSHLV+ALY+VCG+RGFFY+PK+RREAE L G P +G L
Sbjct: 27 SQRLCGSHLVDALYMVCGDRGFFYSPKSRREAEPLLGFLSPKSGQENEVDEYPYKEQGEL 86
Query: 87 Q-KRGIVEQCCTSICSLYQLENYCN 110
+ KRGIVEQCC C+++ L+NYCN
Sbjct: 87 KVKRGIVEQCCHRPCNIFDLQNYCN 111
>gi|3127060|gb|AAC78289.1| (AF050524) proinsulin-like protein BKRA [synthetic construct]
Length = 54
Score = 88.2 bits (217), Expect = 1e-17
Identities = 53/86 (61%), Positives = 53/86 (61%), Gaps = 33/86 (38%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Sbjct: 2 FVNQHLCGSHLVEALYLVCGERGFFYTPKT------------------------------ 31
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
KRGIVEQCCTSICSLYQLENYCN
Sbjct: 32 ---KRGIVEQCCTSICSLYQLENYCN 54
>gi|124547|sp|P01333|INS_ANAPL INSULIN PRECURSOR
gi|69328|pir||IPDK insulin precursor - duck (tentative sequence)
Length = 81
Score = 87.8 bits (216), Expect = 2e-17
Identities = 52/85 (61%), Positives = 57/85 (66%), Gaps = 7/85 (8%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG-S 85
NQHLCGSHLVEALYLVCGERGFFY+PKT + E L GP G + L +
Sbjct: 3 NQHLCGSHLVEALYLVCGERGFFYSPKTXXDVEQ------PLVNGPLHGEVGELPFQHEE 56
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
Q GIVEQCC + CSLYQLENYCN
Sbjct: 57 YQXXGIVEQCCENPCSLYQLENYCN 81
>gi|13517225|gb|AAK28712.1| (AF199588) preproinsulin [Pantodon buchholzi]
Length = 110
Score = 86.7 bits (213), Expect = 3e-17
Identities = 43/85 (50%), Positives = 56/85 (65%), Gaps = 1/85 (1%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+QHLCGSHLV+ALY+VCGE+GFFY PKT+R+ + L P +G L
Sbjct: 26 SQHLCGSHLVDALYMVCGEKGFFYQPKTKRDVDPLLGFLSPKSAQENEADEYPYKDQGDL 85
Query: 87 Q-KRGIVEQCCTSICSLYQLENYCN 110
+ KRGIVEQCC C+++ L+NYCN
Sbjct: 86 KVKRGIVEQCCHHPCNIFDLQNYCN 110
>gi|69309|pir||INSH insulin precursor - sheep
Length = 77
Score = 85.5 bits (210), Expect = 7e-17
Identities = 61/86 (70%), Positives = 65/86 (74%), Gaps = 9/86 (10%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK E E QVG +EL GGPGAG L+
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA--EVEGPQVGALELAGGPGAGGLEGPP--- 55
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+GIVEQCC +CSLYQLENYCN
Sbjct: 56 ----QGIVEQCCAGVCSLYQLENYCN 77
>gi|69317|pir||INMSSP insulin - Egyptian spiny mouse (tentative sequence)
Length = 51
Score = 84.3 bits (207), Expect = 2e-16
Identities = 48/86 (55%), Positives = 51/86 (58%), Gaps = 35/86 (40%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV+QHLCGSHLVEALYLVCGERGFFYTPK+
Sbjct: 1 FVBQHLCGSHLVEALYLVCGERGFFYTPKS------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIV+QCCTSICSLYQLENYCN
Sbjct: 31 -----GIVDQCCTSICSLYQLENYCN 51
>gi|14161273|gb|AAK54684.1| (AF282408) preproinsulin [Hiodon alosoides]
Length = 110
Score = 84.0 bits (206), Expect = 3e-16
Identities = 42/85 (49%), Positives = 54/85 (63%), Gaps = 1/85 (1%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+QHLCGSHLV+ALY+VCGE+GFFY PKT+R+ + L P +G L
Sbjct: 26 SQHLCGSHLVDALYMVCGEKGFFYQPKTKRDVDPLLGFLSPKSAQENEADEYPYKDQGDL 85
Query: 87 Q-KRGIVEQCCTSICSLYQLENYCN 110
+ KRGIVEQCC C+++ L YCN
Sbjct: 86 KVKRGIVEQCCHRPCNIFDLNQYCN 110
>gi|13517221|gb|AAK28710.1| (AF199586) preproinsulin [Chitala chitala]
Length = 111
Score = 83.2 bits (204), Expect = 3e-16
Identities = 46/86 (53%), Positives = 54/86 (62%), Gaps = 2/86 (2%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKT-RREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
NQHLCGSHLVEALYLVCGERGFFY PK +R+AE L G P +G
Sbjct: 26 NQHLCGSHLVEALYLVCGERGFFYNPKMDKRDAEPLLGFLSPKSGLENEVDEYPFKDQGD 85
Query: 86 LQ-KRGIVEQCCTSICSLYQLENYCN 110
++ KRGIVEQCC C+++ YCN
Sbjct: 86 VKMKRGIVEQCCHRPCNIFDQNQYCN 111
>gi|69316|pir||INHY insulin - hamster
Length = 51
Score = 81.3 bits (199), Expect = 1e-15
Identities = 49/86 (56%), Positives = 51/86 (58%), Gaps = 35/86 (40%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK+
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKS------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIV+QCCTSICSLYQLENYCN
Sbjct: 31 -----GIVDQCCTSICSLYQLENYCN 51
>gi|69303|pir||INWHP insulin - sperm whale
gi|69304|pir||INWHF insulin - finback whale (tentative sequence)
Length = 51
Score = 80.9 bits (198), Expect = 2e-15
Identities = 50/86 (58%), Positives = 50/86 (58%), Gaps = 35/86 (40%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCCTSICSLYQLENYCN
Sbjct: 31 -----GIVEQCCTSICSLYQLENYCN 51
>gi|4558198|pdb|1ZEI|A Chain A, Cross-Linked B28 Asp Insulin
gi|4558199|pdb|1ZEI|B Chain B, Cross-Linked B28 Asp Insulin
gi|4558200|pdb|1ZEI|C Chain C, Cross-Linked B28 Asp Insulin
gi|4558201|pdb|1ZEI|D Chain D, Cross-Linked B28 Asp Insulin
gi|4558202|pdb|1ZEI|E Chain E, Cross-Linked B28 Asp Insulin
gi|4558203|pdb|1ZEI|F Chain F, Cross-Linked B28 Asp Insulin
Length = 53
Score = 80.1 bits (196), Expect = 3e-15
Identities = 49/86 (56%), Positives = 50/86 (57%), Gaps = 33/86 (38%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYT K
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTDKA------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+GIVEQCCTSICSLYQLENYCN
Sbjct: 31 ---AKGIVEQCCTSICSLYQLENYCN 53
>gi|494923|pdb|6INS|E Chain E, Insulin (Peptide-Linked, 29b - 1a, Des-30b)
gi|494924|pdb|6INS|F Chain F, Insulin (Peptide-Linked, 29b - 1a, Des-30b)
Length = 50
Score = 80.1 bits (196), Expect = 3e-15
Identities = 50/86 (58%), Positives = 50/86 (58%), Gaps = 36/86 (41%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPK------------------------------- 29
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCCTSICSLYQLENYCN
Sbjct: 30 -----GIVEQCCTSICSLYQLENYCN 50
Database: nr
Posted date: Oct 1, 2001 12:31 AM
Number of letters in database: 242,984,850
Number of sequences in database: 764,431
Lambda K H
0.322 0.141 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,640,526
Number of Sequences: 764431
Number of extensions: 1733243
Number of successful extensions: 4269
Number of sequences better than 10.0: 476
Number of HSP's better than 10.0 without gapping: 468
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3522
Number of HSP's gapped (non-prelim): 582
length of query: 110
length of database: 242,984,850
effective HSP length: 86
effective length of query: 24
effective length of database: 177,243,784
effective search space: 4253850816
effective search space used: 4253850816
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
