Legend:
- means that the alignment score was below the threshold on the previous iteration
- means that the alignment was checked on the previous iteration
Hit list size
Sequences with E-value BETTER than threshold
Score E
Sequences producing significant alignments: (bits) Value
gi|4557671|ref|NP_000198.1| proinsulin precursor [Homo sapiens] ... 143 2e-34
gi|266373|sp|P30406|INS_MACFA INSULIN PRECURSOR >gi|86627|pir||J... 143 3e-34
gi|266377|sp|P30410|INS_PANTR INSULIN PRECURSOR >gi|283944|pir||... 142 5e-34
gi|9506815|ref|NP_062002.1| insulin [Rattus norvegicus] >gi|1245... 142 6e-34
gi|266362|sp|P30407|INS_CERAE INSULIN PRECURSOR >gi|283935|pir||... 141 8e-34
gi|124588|sp|P01313|INS_CRILO INSULIN PRECURSOR >gi|2137094|pir|... 141 8e-34
gi|2497407|sp|Q62587|INS_PSAOB INSULIN PRECURSOR >gi|1370283|emb... 140 3e-33
gi|9506817|ref|NP_062003.1| insulin 2 [Rattus norvegicus] >gi|12... 139 4e-33
gi|6680463|ref|NP_032413.1| insulin II [Mus musculus] >gi|124519... 138 1e-32
gi|307072|gb|AAA59179.1| (L15440) insulin [Homo sapiens] 135 9e-32
gi|124587|sp|P01332|INS_CHICK INSULIN PRECURSOR >gi|69325|pir||I... 133 3e-31
gi|208668|gb|AAA72172.1| (J02547) synthetic preproinsulin [synth... 133 4e-31
gi|124575|sp|P01321|INS_CANFA INSULIN PRECURSOR >gi|69312|pir||I... 130 2e-30
gi|6680461|ref|NP_032412.1| insulin I [Mus musculus] >gi|124511|... 127 1e-29
gi|124553|sp|P10604|INS_AOTTR INSULIN PRECURSOR >gi|104987|pir||... 127 2e-29
gi|124526|sp|P12707|INS2_XENLA INSULIN 2 PRECURSOR >gi|69333|pir... 126 3e-29
gi|12841054|dbj|BAB25058.1| (AK007482) putative [Mus musculus] 126 3e-29
gi|223965|prf||1006230A insulin,pro- [Macaca mulatta] 125 8e-29
gi|12644021|sp|P81025|INS_ORENI INSULIN PRECURSOR >gi|4558782|gb... 125 1e-28
gi|58103|emb|CAA23424.1| (V00082) reading frame proinsulin [synt... 124 1e-28
gi|124594|sp|P01335|INS_CYPCA INSULIN PRECURSOR >gi|69334|pir||I... 124 2e-28
gi|229391|prf||720460A insulin 1,pro [Rattus norvegicus] 123 2e-28
gi|229392|prf||720460B insulin 2,pro [Rattus norvegicus] 123 2e-28
gi|14906249|gb|AAK72558.1| (AY038604) insulin [Spermophilus trid... 122 5e-28
gi|124513|sp|P12706|INS1_XENLA INSULIN 1 PRECURSOR >gi|69332|pir... 122 6e-28
gi|13517225|gb|AAK28712.1| (AF199588) preproinsulin [Pantodon bu... 121 1e-27
gi|13991923|gb|AAK51558.1|AF373021_1 (AF373021) preproinsulin [C... 121 1e-27
gi|13517219|gb|AAK28709.1| (AF199585) preproinsulin [Catostomus ... 120 2e-27
gi|124638|sp|P01341|INS_LOPPI INSULIN PRECURSOR >gi|69346|pir||I... 120 3e-27
gi|14161273|gb|AAK54684.1| (AF282408) preproinsulin [Hiodon alos... 120 3e-27
gi|9408409|gb|AAF87285.1|AF227187_1 (AF227187) preproinsulin [Ra... 116 3e-26
gi|13517227|gb|AAK28713.1| (AF199589) preproinsulin [Osteoglossu... 116 4e-26
gi|9973534|sp|Q9W7R2|INS_VERMO INSULIN PRECURSOR >gi|5381267|dbj... 115 1e-25
gi|124581|sp|P01329|INS_CAVPO INSULIN PRECURSOR >gi|69322|pir||I... 114 1e-25
gi|1708499|sp|P51463|INS_SELRF INSULIN PRECURSOR >gi|2147962|pir... 114 2e-25
gi|387059|gb|AAA37041.1| (K02233) insulin [Cavia porcellus] 114 2e-25
gi|13517221|gb|AAK28710.1| (AF199586) preproinsulin [Chitala chi... 113 3e-25
gi|1352467|sp|P01311|INS_RABIT INSULIN PRECURSOR >gi|1083159|pir... 111 1e-24
gi|12053668|emb|CAC20109.1| (AJ237750) insulin [Danio rerio] 109 6e-24
gi|124651|sp|P17715|INS_OCTDE INSULIN PRECURSOR >gi|538567|pir||... 108 9e-24
gi|9973509|sp|O73727|INS_BRARE INSULIN PRECURSOR >gi|2935704|gb|... 108 1e-23
gi|3885494|gb|AAC77920.1| (AF064555) preproinsulin [Sus scrofa] 107 2e-23
gi|12643972|sp|P01315|INS_PIG INSULIN PRECURSOR 106 3e-23
gi|2135482|pir||I76705 insulin-like growth factor II precursor -... 105 8e-23
gi|124615|sp|P21563|INS_RODSP INSULIN PRECURSOR >gi|102414|pir||... 105 9e-23
gi|13517223|gb|AAK28711.1| (AF199587) preproinsulin [Gnathonemus... 105 1e-22
gi|213445|gb|AAA49414.1| (J00936) preproinsulin [Oncorhynchus ke... 104 2e-22
gi|87954|pir||S02423 insulin-like growth factor II precursor, sp... 103 3e-22
gi|2135956|pir||I67610 insulin-like growth factor II, domains A-... 103 3e-22
gi|33004|emb|CAA27249.1| (X03562) put. IGF-II [Homo sapiens] 103 4e-22
gi|4504609|ref|NP_000603.1| insulin-like growth factor 2 (somato... 102 5e-22
gi|124657|sp|P04667|INS_ONCKE INSULIN PRECURSOR >gi|69342|pir||I... 102 5e-22
gi|1708500|sp|P01318|INS_SHEEP INSULIN PRECURSOR >gi|405982|gb|A... 102 6e-22
gi|124650|sp|P01342|INS_MYXGL INSULIN PRECURSOR >gi|69353|pir||I... 102 8e-22
gi|33044|emb|CAA29517.1| (X06160) precursor polypeptide (AA -24 ... 101 1e-21
gi|64362|emb|CAA24983.1| (X00148) preproinsulin [Oncorhynchus keta] 101 1e-21
gi|12643999|sp|P13190|INS_CALMI INSULIN PRECURSOR 100 2e-21
gi|124564|sp|P01317|INS_BOVIN INSULIN PRECURSOR >gi|1070561|pir|... 100 3e-21
gi|124616|sp|P01310|INS_HORSE INSULIN PRECURSOR >gi|69301|pir||I... 100 4e-21
gi|56710|emb|CAA25427.1| (X00911) pot. MSA-precursor [Rattus nor... 99 6e-21
gi|69306|pir||IPPG insulin precursor - pig 99 8e-21
gi|13937375|ref|NP_113699.1| insulin-like growth factor II (soma... 99 8e-21
gi|13517217|gb|AAK28708.1| (AF199584) preproinsulin [Ambloplites... 98 9e-21
gi|14773148|ref|XP_028183.1| insulin-like growth factor 2 (somat... 98 1e-20
gi|3041701|sp|P51459|IGF2_HORSE INSULIN-LIKE GROWTH FACTOR II PR... 98 2e-20
gi|1289271|emb|CAA65862.1| (X97225) insulin-like growth factor I... 97 3e-20
gi|729826|sp|Q08279|IGF2_CAVPO INSULIN-LIKE GROWTH FACTOR II PRE... 97 3e-20
gi|6754310|ref|NP_034644.1| insulin-like growth factor 2 [Mus mu... 97 3e-20
gi|729827|sp|Q02816|IGF2_ONCMY INSULIN-LIKE GROWTH FACTOR II PRE... 97 3e-20
gi|33048|emb|CAA29518.1| (X06161) precursor polypeptide (AA -24 ... 97 4e-20
gi|124547|sp|P01333|INS_ANAPL INSULIN PRECURSOR >gi|69328|pir||I... 95 8e-20
gi|56713|emb|CAA25429.1| (X00911) pot. MSA-precursor [Rattus nor... 95 1e-19
gi|124365|sp|P22334|ILP_BRACL INSULIN-LIKE PEPTIDE PRECURSOR >gi... 95 1e-19
gi|14758705|ref|XP_052653.1| insulin-like growth factor 1 (somat... 92 7e-19
gi|14571867|gb|AAK67297.1|AF282621_1 (AF282621) IGFII-GFP fusion... 92 8e-19
gi|12644472|sp|Q95222|IGF1_RABIT INSULIN-LIKE GROWTH FACTOR I PR... 92 1e-18
gi|12231523|gb|AAG49142.1|AF225573_1 (AF225573) SooQI-507GFP fus... 92 1e-18
gi|124265|sp|P08024|IGFB_RAT INSULIN-LIKE GROWTH FACTOR IB PRECU... 92 1e-18
gi|124253|sp|P16501|IGF1_XENLA INSULIN-LIKE GROWTH FACTOR I PREC... 91 1e-18
gi|1100903|gb|AAA96152.1| (U40870) insulin-like growth factor-I ... 91 2e-18
gi|108319|pir||A34938 insulin-like growth factor IA precursor - ... 91 2e-18
gi|1850346|gb|AAB48032.1| (U75390) insulin-like growth factor 1 ... 91 2e-18
gi|14758736|ref|XP_052652.1| insulin-like growth factor 1 (somat... 90 2e-18
gi|109037|pir||S22878 insulin-like growth factor I precursor, sp... 90 3e-18
gi|109035|pir||B33390 insulin-like growth factor I precursor (cl... 90 3e-18
gi|8100793|gb|AAF72409.1| (AF210387) insulin-like growth factor ... 90 3e-18
gi|69362|pir||IGGP1 insulin-like growth factor I precursor - gui... 90 3e-18
gi|124262|sp|P08025|IGFA_RAT INSULIN-LIKE GROWTH FACTOR IA PRECU... 90 3e-18
gi|164474|gb|AAA31043.1| (M31175) insulin-like growth factor I p... 90 3e-18
gi|124248|sp|P17647|IGF1_CAVPO INSULIN-LIKE GROWTH FACTOR I PREC... 90 4e-18
gi|462403|sp|P33712|IGF1_CANFA INSULIN-LIKE GROWTH FACTOR I PREC... 90 4e-18
gi|6754308|ref|NP_034642.1| insulin-like growth factor 1 [Mus mu... 90 4e-18
gi|3309072|gb|AAC26006.1| (AF074980) insulin-like growth factor-... 90 5e-18
gi|92423|pir||A26859 insulin-like growth factor IB precursor - r... 89 5e-18
gi|165931|gb|AAA80533.1| (M30653) insulin-like growth factor I [... 89 6e-18
gi|183120|gb|AAA52543.1| (M29644) insulin-like growth factor I p... 89 6e-18
gi|14571865|gb|AAK67296.1|AF282620_1 (AF282620) SIGF1-GFP fusion... 89 7e-18
gi|204752|gb|AAA41386.1| (M17335) insulin like growth factor I [... 89 7e-18
gi|1815685|gb|AAB47485.1| (U85272) prepro IGF-Ia [Equus caballus] 89 8e-18
gi|124251|sp|P16545|IGF1_PIG INSULIN-LIKE GROWTH FACTOR I PRECUR... 89 9e-18
gi|1708431|sp|P51462|IGF1_COTJA INSULIN-LIKE GROWTH FACTOR I PRE... 88 9e-18
gi|1070562|pir||IGBO1 insulin-like growth factor IA precursor - ... 88 9e-18
gi|14279401|gb|AAK58584.1|AF268051_1 (AF268051) insulin-like gro... 88 1e-17
gi|124261|sp|P05017|IGFA_MOUSE INSULIN-LIKE GROWTH FACTOR IA PRE... 88 1e-17
gi|124247|sp|P07455|IGF1_BOVIN INSULIN-LIKE GROWTH FACTOR I PREC... 88 1e-17
gi|13936438|gb|AAK49814.1|AF246977_1 (AF246977) 45 kDa IGFI-GFP ... 88 1e-17
gi|1083101|pir||JC2483 insulin-like growth factor-I precursor - ... 88 1e-17
gi|2118612|pir||A33390 insulin-like growth factor I precursor, s... 88 1e-17
gi|124252|sp|P10763|IGF1_SHEEP INSULIN-LIKE GROWTH FACTOR I PREC... 88 1e-17
gi|223828|prf||1001199A insulin-like growth factor I precursor [... 88 1e-17
gi|11024682|ref|NP_000609.1| insulin-like growth factor 1 (somat... 88 1e-17
gi|111863|pir||B40912 insulin-like growth factor I precursor for... 88 2e-17
gi|124249|sp|P18254|IGF1_CHICK INSULIN-LIKE GROWTH FACTOR I PREC... 88 2e-17
gi|7677623|gb|AAF67202.1|AF260131_1 (AF260131) IGF-I [Coturnix j... 87 2e-17
gi|13249283|gb|AAK16727.1|AF332865_1 (AF332865) insulin-like gro... 87 2e-17
gi|63530|emb|CAA23707.1| (V00416) part of reading frame [Gallus ... 87 3e-17
gi|1708430|sp|P51457|IGF1_CAPHI INSULIN-LIKE GROWTH FACTOR I PRE... 87 3e-17
gi|111862|pir||A40912 insulin-like growth factor I precursor for... 87 3e-17
gi|2497406|sp|Q90326|IGFB_CYPCA INSULIN-LIKE GROWTH FACTOR I, JU... 87 3e-17
gi|225446|prf||1303322A insulin [Oncorhynchus keta] 87 3e-17
gi|9457240|gb|AAB37702.2| (S82374) insulin-like growth factor I ... 87 3e-17
gi|124259|sp|P10764|IGF2_SHEEP INSULIN-LIKE GROWTH FACTOR II PRE... 87 3e-17
gi|2497405|sp|Q90325|IGFA_CYPCA INSULIN-LIKE GROWTH FACTOR I, AD... 86 5e-17
gi|3982555|gb|AAC83444.1| (AF001006) insulin-like growth factor-... 86 5e-17
gi|345552|pir||B44012 proIGF-IA-2=insulin-like growth factor I p... 86 5e-17
gi|1352443|sp|P23695|IGF2_PIG INSULIN-LIKE GROWTH FACTOR II PREC... 86 6e-17
gi|124254|sp|P07456|IGF2_BOVIN INSULIN-LIKE GROWTH FACTOR II PRE... 86 7e-17
gi|420123|pir||B60738 insulin-like growth factor II precursor - pig 85 8e-17
gi|3158363|gb|AAC17495.1| (AF033801) insulin-like growth factor ... 85 9e-17
gi|1994|emb|CAA35527.1| (X17492) insulin like growth factor I (1... 85 1e-16
gi|2282046|gb|AAB64195.1| (AF007943) insulin-like growth factor ... 85 1e-16
gi|7546360|pdb|1EFE|A Chain A, An Active Mini-Proinsulin, M2pi 85 1e-16
gi|1708432|sp|P51458|IGF1_HORSE INSULIN-LIKE GROWTH FACTOR I PRE... 84 2e-16
gi|2118611|pir||S58036 insulin-like growth factor I, precursor -... 84 3e-16
gi|423313|pir||S32558 insulin-like growth factor II - sheep >gi|... 84 3e-16
gi|345553|pir||C44012 insulin-like growth factor I precursor, sp... 83 3e-16
gi|738041|prf||1924192A insulin-like growth factor I [Oncorhynch... 83 4e-16
gi|7649259|gb|AAF65819.1| (AF247658) insulin-like growth factor-... 83 5e-16
gi|124250|sp|P17085|IGF1_ONCKI INSULIN-LIKE GROWTH FACTOR I PREC... 83 5e-16
gi|2133793|pir||S66484 insulin-like growth factor II precursor -... 83 6e-16
gi|213811|gb|AAA18211.1| (M81904) insulin-like growth factor I [... 83 6e-16
gi|729825|sp|Q02815|IGF1_ONCMY INSULIN-LIKE GROWTH FACTOR I PREC... 83 6e-16
gi|56435|emb|CAA29436.1| (X06043) IGF-IA precursor [Rattus norve... 82 7e-16
gi|461660|sp|P33719|BXA2_SAMCY BOMBYXIN A-2 HOMOLOG PRECURSOR >g... 82 7e-16
gi|8571480|gb|AAF76900.1|AF276074_1 (AF276074) insulin-like grow... 82 8e-16
gi|345551|pir||A44012 insulin-like growth factor I prohormone (a... 82 9e-16
gi|3687742|gb|AAC62228.1| (AF061278) insulin-like growth factor ... 82 9e-16
gi|2894577|emb|CAA17123.1| (AL021880) insulin-like growth factor... 82 1e-15
gi|58145|emb|CAA28759.1| (X05113) synthetic somatomedin C (AA 1-... 82 1e-15
gi|632198|pir||B54270 insulin-like growth factor-I precursor (cl... 82 1e-15
gi|224256|prf||1012293A insulin-like growth factor II precursor ... 82 1e-15
gi|2808535|emb|CAA11145.1| (AJ223165) IGF-II precursor [Taenopyg... 82 1e-15
gi|7438601|pir||T10897 insulin-like growth factor II precursor -... 82 1e-15
gi|632197|pir||A54270 insulin-like growth factor-I precursor (cl... 82 1e-15
gi|3176823|gb|AAC18833.1| (AF063216) insulin-like growth factor ... 81 1e-15
gi|2136466|pir||I53642 insulin-like growth factor II precursor -... 81 2e-15
gi|69309|pir||INSH insulin precursor - sheep 81 2e-15
gi|224501|prf||1106261A insulin-like growth factor II variant [H... 81 2e-15
gi|5103031|dbj|BAA78767.1| (AB028636) IGF1 [Mesocricetus auratus] 81 2e-15
gi|1364191|emb|CAA37620.1| (X53553) insulin-like growth factor I... 81 2e-15
gi|1808660|emb|CAA71789.1| (Y10830) prepro insulin-like growth f... 81 2e-15
gi|1170518|sp|P41694|IGF2_MUSVI INSULIN-LIKE GROWTH FACTOR II PR... 81 2e-15
gi|488155|gb|AAA18212.1| (M81904) insulin-like growth factor I [... 81 2e-15
gi|3158361|gb|AAC17494.1| (AF033800) insulin-like growth factor ... 81 2e-15
gi|69352|pir||IPRYM insulin precursor - marbled electric ray (fr... 80 3e-15
gi|2625161|gb|AAB86652.1| (AF033796) insulin-like growth factor ... 80 3e-15
gi|115182|sp|P26742|BXB8_BOMMO BOMBYXIN B-8 PRECURSOR (BBX-B8) (... 80 3e-15
gi|3776078|emb|CAA08766.1| (AJ009655) insulin [Homo sapiens] 80 3e-15
gi|2143806|pir||I52680 insulin-like growth factor II - rat (frag... 80 4e-15
gi|632199|pir||C54270 insulin-like growth factor-I precursor (cl... 80 4e-15
gi|115175|sp|P26733|BXB1_BOMMO BOMBYXIN B-1 PRECURSOR (BBX-B1) (... 80 4e-15
gi|69357|pir||IPMTB1 bombyxin B-1 precursor - silkworm >gi|15596... 80 4e-15
gi|4104007|gb|AAD01917.1| (AF030573) prepro-insulin-like growth ... 80 4e-15
gi|2569961|emb|CAA73162.1| (Y12583) insulin-like growth factor [... 80 4e-15
gi|115176|sp|P26734|BXB2_BOMMO BOMBYXIN B-2 PRECURSOR (BBX-B2) (... 80 5e-15
gi|69358|pir||IPMTB2 bombyxin B-2 precursor - silkworm >gi|15596... 80 5e-15
gi|115186|sp|P26735|BXC2_BOMMO BOMBYXIN C-2 PRECURSOR (BBX-C2) (... 80 5e-15
gi|632196|pir||D54270 insulin-like growth factor-I precursor (cl... 80 5e-15
gi|115184|sp|P15410|BXC1_BOMMO BOMBYXIN C-1 PRECURSOR (BBX-C1) (... 79 6e-15
gi|9664869|gb|AAF97244.1|AF283002_1 (AF283002) insulin-like grow... 79 6e-15
gi|2736077|gb|AAB94052.1| (AF016922) insulin-like growth factor ... 79 7e-15
gi|115181|sp|P26741|BXB7_BOMMO BOMBYXIN B-7 PRECURSOR (BBX-B7) (... 79 8e-15
gi|3483058|emb|CAA09268.1| (AJ010603) preproinsulin-like growth ... 79 8e-15
gi|115178|sp|P26738|BXB4_BOMMO BOMBYXIN B-4 PRECURSOR (BBX-B4) (... 78 1e-14
gi|3483056|emb|CAA09267.1| (AJ010602) preproinsulin-like growth ... 78 1e-14
gi|6319169|gb|AAF07193.1|AF194333_1 (AF194333) insulin-like grow... 78 1e-14
gi|11275220|pir||PC7082 epidermal growth factor/single chain ins... 78 1e-14
gi|102907|pir||JQ0832 bombyxin B-7 - silkworm strain Showa >gi|2... 78 1e-14
gi|102895|pir||JQ0816 bombyxin A-7 - silkworm strain Showa >gi|2... 78 1e-14
gi|208030|gb|AAA72971.1| (M60420) insulin-like growth factor 2 [... 78 1e-14
gi|2289113|gb|AAB64356.1| (U82395) proinsulin [Callorhinchus milii] 78 1e-14
gi|3127060|gb|AAC78289.1| (AF050524) proinsulin-like protein BKR... 78 2e-14
gi|2655872|emb|CAA04657.1| (AJ001297) IGF2 protein [Callithrix j... 77 2e-14
gi|9972779|sp|Q17194|BXBA_BOMMO BOMBYXIN B-10 PRECURSOR (BBX-B10... 77 2e-14
gi|227567|prf||1707201B insulin-like growth factor 2 [Sus scrofa... 77 3e-14
gi|3982553|gb|AAC83443.1| (AF001005) insulin-like growth factor-... 77 3e-14
gi|115180|sp|P26740|BXB6_BOMMO BOMBYXIN B-6 PRECURSOR (BBX-B6) (... 77 3e-14
gi|738556|prf||2001274C insulin-like growth factor II [Odocoileu... 77 3e-14
gi|9973400|sp|Q28933|IGF1_SUNMU INSULIN-LIKE GROWTH FACTOR I PRE... 77 3e-14
gi|115171|sp|P26730|BXA7_BOMMO BOMBYXIN A-7 PRECURSOR (BBX-A7) (... 77 4e-14
gi|1000058|pdb|1IGL| Insulin-Like Growth Factor Ii (Igf-Ii, I... 77 4e-14
gi|738557|prf||2001274D insulin-like growth factor II [Ovis aries] 77 4e-14
gi|115170|sp|P26729|BXA6_BOMMO BOMBYXIN A-6 PRECURSOR (BBX-A6) (... 76 5e-14
gi|115177|sp|P26737|BXB3_BOMMO BOMBYXIN B-3 PRECURSOR (BBX-B3) (... 76 5e-14
gi|115168|sp|P26727|BXA4_BOMMO BOMBYXIN A-4 PRECURSOR (BBX-A4) (... 76 6e-14
gi|738554|prf||2001274A insulin-like growth factor I [Odocoileus... 76 6e-14
gi|5107517|pdb|1BQT| Three-Dimensional Structure Of Human Ins... 76 8e-14
gi|209366|gb|AAA72455.1| (M10170) synthetic somatomedin-C/insuli... 75 8e-14
gi|231658|sp|P29519|BXBC_BOMMO BOMBYXIN B-12 PRECURSOR (BBX-B12)... 75 8e-14
gi|109033|pir||S07198 insulin-like growth factor - sheep >gi|738... 75 8e-14
gi|208526|gb|AAA72579.1| (M16249) insulin-like growth factor [sy... 75 8e-14
gi|69349|pir||INFI insulin precursor - spotted ratfish (fragment... 75 9e-14
gi|208429|gb|AAA72201.1| (J03738) insulin-like growth factor I [... 75 9e-14
gi|9972776|sp|Q17192|BXA1_BOMMO BOMBYXIN A-1 PRECURSOR (BBX-A1) ... 75 1e-13
gi|146446|gb|AAA53535.1| (M22044) insulin-like growth factor I [... 75 1e-13
gi|461659|sp|P33718|BXA1_SAMCY BOMBYXIN A-1 HOMOLOG PRECURSOR >g... 75 1e-13
gi|2133584|pir||S69479 bombyxin A-5 precursor - silkworm 75 1e-13
gi|115173|sp|P26732|BXA9_BOMMO BOMBYXIN A-9 PRECURSOR (BBX-A9) (... 75 1e-13
gi|85535|pir||S09146 insulin II precursor - chum salmon (fragment) 75 1e-13
gi|2133591|pir||S69490 bombyxin B-10 precursor - silkworm 75 1e-13
gi|213447|gb|AAA49415.1| (K03487) preproinsulin [Oncorhynchus ke... 75 2e-13
gi|2808466|emb|CAA76136.1| (Y16248) IGF-1 [Bubalus bubalis] 74 2e-13
gi|109123|pir||S08567 insulin-like growth factor - sheep 74 2e-13
gi|115169|sp|P26728|BXA5_BOMMO BOMBYXIN A-5 PRECURSOR (BBX-A5) (... 74 3e-13
gi|208431|gb|AAA72202.1| (J03739) insulin-like growth factor [sy... 73 3e-13
gi|3158368|gb|AAC17496.1| (AF033804) insulin-like growth factor ... 73 3e-13
gi|115167|sp|P26726|BXA3_BOMMO BOMBYXIN A-3 PRECURSOR (BBX-A3) (... 73 3e-13
gi|1103534|emb|CAA92276.1| (Z68151) IGF2 [Bos taurus] 73 3e-13
gi|208433|gb|AAA72203.1| (J03740) insulin-like growth factor [sy... 73 4e-13
gi|461662|sp|P33721|BXB1_SAMCY BOMBYXIN B-1 HOMOLOG PRECURSOR >g... 73 4e-13
gi|69335|pir||INCD insulin - cod (Gadus sp.) 73 6e-13
gi|8569480|pdb|3LRI|A Chain A, Solution Structure And Backbone D... 73 6e-13
gi|227566|prf||1707201A insulin-like growth factor 1 [Sus scrofa... 73 6e-13
gi|69339|pir||INTU2 insulin 2 - tuna 72 7e-13
gi|12644159|sp|P21808|BXE1_BOMMO BOMBYXIN E-1 PRECURSOR (BBX-E1)... 72 7e-13
gi|4558198|pdb|1ZEI|A Chain A, Cross-Linked B28 Asp Insulin >gi|... 72 9e-13
gi|69307|pir||INEL insulin - elephant 72 1e-12
gi|69316|pir||INHY insulin - hamster 72 1e-12
gi|69303|pir||INWHP insulin - sperm whale >gi|69304|pir||INWHF i... 72 1e-12
gi|69347|pir||INAFP insulin - allmouth goosefish 72 1e-12
gi|461663|sp|P33722|BXB2_SAMCY BOMBYXIN B-2 HOMOLOG PRECURSOR >g... 72 1e-12
gi|69317|pir||INMSSP insulin - Egyptian spiny mouse (tentative s... 72 1e-12
gi|69345|pir||INGXA insulin - alligator gar 72 1e-12
gi|165928|gb|AAA31544.1| (M89787) insulin-like growth factor I [... 72 1e-12
gi|69343|pir||INFLE insulin - European flounder 71 2e-12
gi|69338|pir||INFIS insulin - shorthorn sculpin 71 2e-12
gi|7532878|gb|AAF63265.1| (AF216775) insulin-like growth factor ... 71 2e-12
gi|69336|pir||INTF1 insulin 1 - toadfish (tentative sequence) 71 2e-12
gi|494923|pdb|6INS|E Chain E, Insulin (Peptide-Linked, 29b - 1a,... 71 2e-12
gi|69326|pir||INTK insulin - turkey (tentative sequence) >gi|693... 71 2e-12
gi|7438595|pir||S44470 insulin I2 - North American paddlefish (P... 71 2e-12
gi|7438597|pir||S61361 insulin - Amphiuma tridactylum 71 2e-12
gi|85464|pir||A24634 insulin - spotted ratfish 71 2e-12
gi|930004|emb|CAA37861.1| (X53867) insulin-like growth factor II... 71 2e-12
gi|69329|pir||INGS insulin - goose 70 3e-12
gi|7767505|gb|AAF69129.1| (AF225876) insulin-like growth factor ... 70 3e-12
gi|551232|emb|CAA55831.1| (X79244) ubiquitous insulin-like growt... 70 3e-12
gi|69320|pir||INCB insulin - Chinchilla brevicaudata 70 4e-12
gi|69305|pir||INWH1S insulin - sei whale 70 4e-12
gi|69310|pir||INGT insulin - goat 70 4e-12
gi|69340|pir||INON insulin [validated] - pink salmon >gi|69341|p... 70 5e-12
gi|7438594|pir||S44469 insulin I1 - North American paddlefish (P... 70 5e-12
gi|115183|sp|P26743|BXB9_BOMMO BOMBYXIN B-9 PRECURSOR (BBX-B9) (... 69 6e-12
gi|69321|pir||INPQ insulin - crested porcupine 69 6e-12
gi|7438602|pir||A59151 insulin precursor - jack bean (fragments) 69 6e-12
gi|69330|pir||INAQ insulin - American alligator 69 7e-12
gi|482755|pir||A61125 insulin - American eel 69 7e-12
gi|462404|sp|P33717|IGF2_CHICK INSULIN-LIKE GROWTH FACTOR II (IG... 69 8e-12
gi|86565|pir||JQ0362 insulin - North American opossum 69 9e-12
gi|115179|sp|P26739|BXB5_BOMMO BOMBYXIN B-5 PRECURSOR (BBX-B5) (... 69 9e-12
gi|69311|pir||INCMA insulin - Arabian camel (tentative sequence) 68 1e-11
gi|124266|sp|P22618|IGF_MYXGL INSULIN-LIKE GROWTH FACTOR PRECURS... 68 1e-11
gi|69354|pir||INLMS insulin - sea lamprey 68 1e-11
gi|1083924|pir||A53697 insulin-like growth factor I, brain-speci... 67 2e-11
gi|69313|pir||INCT insulin - cat 67 3e-11
gi|126335|sp|P15131|LIRP_LOCMI LIRP PRECURSOR (LOCUSTA INSULIN-R... 67 3e-11
gi|9530|emb|CAA34889.1| (X17024) precursor polypeptide (AA -31 t... 67 3e-11
gi|69348|pir||INEN insulin - elephantfish (Callorhynchus milii) 67 3e-11
gi|538566|pir||INMKSQ insulin - common squirrel monkey 67 3e-11
gi|69351|pir||INDF insulin - spiny dogfish (tentative sequence) 67 3e-11
gi|2981815|pdb|1SJU| Mini-Proinsulin, Single Chain Insulin An... 67 4e-11
gi|7438596|pir||S63590 insulin - duckbill platypus 66 6e-11
gi|102897|pir||JQ0822 bombyxin A-8 - silkworm >gi|2133589|pir||S... 66 6e-11
gi|115166|sp|P15411|BXA2_BOMMO BOMBYXIN A-2 PRECURSOR (BBX-A2) (... 66 7e-11
gi|115172|sp|P26731|BXA8_BOMMO BOMBYXIN A-8 PRECURSOR (BBX-A8) (... 66 7e-11
gi|7522609|pir||JE0286 insulin-like protein 1 [imported] - Caeno... 65 9e-11
gi|461661|sp|P33720|BXA3_SAMCY BOMBYXIN A-3 HOMOLOG PRECURSOR >g... 65 9e-11
gi|15787614|gb|AAL06242.1| (AY049735) insulin-like growth factor... 65 1e-10
gi|418830|pir||A60740 insulin-like growth factor II - chicken 65 1e-10
gi|85933|pir||JQ0359 insulin - colubrid snake (Zaocys dhumnades) 65 2e-10
gi|9972781|sp|Q17196|BXBB_BOMMO BOMBYXIN B-11 PRECURSOR (BBX-B11... 65 2e-10
gi|2230767|emb|CAA71694.1| (Y10691) pro-insulin like growth fact... 64 2e-10
gi|69331|pir||INRS insulin - western diamondback rattlesnake 64 2e-10
gi|69337|pir||INTO2 insulin 2 - toadfish (tentative sequence) 64 2e-10
gi|33031|emb|CAA27155.1| (X03425) put. IGF-II precursor (175 is ... 64 3e-10
gi|4558029|pdb|1B9G|A Chain A, Insulin-Like-Growth-Factor-1 63 3e-10
gi|103795|pir||S15426 insulin - bowfin 63 5e-10
gi|102890|pir||JQ0826 bombyxin A-10 - silkworm >gi|2133582|pir||... 63 6e-10
gi|224061|prf||1009206A somatomedin A [Homo sapiens] 63 6e-10
gi|213465|gb|AAA72357.1| (L11712) [Oncorhynchus keta insulin gen... 61 1e-09
gi|8132123|gb|AAF73227.1|AF152588_1 (AF152588) insulin-like grow... 61 2e-09
gi|2143547|pir||I49419 insulin II precursor - western wild mouse... 61 2e-09
gi|8132125|gb|AAF73228.1|AF152589_1 (AF152589) insulin-like grow... 60 4e-09
gi|124688|sp||INS_TORMA_1 [Segment 1 of 2] INSULIN PRECURSOR 60 5e-09
gi|393423|emb|CAA50737.1| (X71921) insulin-like growth factor II... 60 5e-09
gi|229541|prf||753014A insulin [Cricetinae gen. sp.] 59 7e-09
gi|213449|gb|AAA49416.1| (K03488) preproinsulin [Oncorhynchus keta] 58 1e-08
gi|13646958|dbj|BAB41098.1| (AB050012) insulin like growth facto... 58 1e-08
gi|69344|pir||INBN2 insulin - skipjack tuna (tentative sequence) 57 2e-08
gi|124621|sp||INS_HYDCO_1 [Segment 1 of 2] INSULIN 57 3e-08
gi|1170570|sp|P41522|INS_ANGAN INSULIN PRECURSOR 57 4e-08
gi|1071942|pir||JL0099 insulin precursor - European eel (fragments) 56 4e-08
gi|2143546|pir||I49418 insulin I precursor - western wild mouse ... 56 5e-08
gi|470321|gb|AAA17540.1| (M61153) insulin [Oryctolagus cuniculus] 56 6e-08
gi|124603|sp||INS_ELEMA_1 [Segment 1 of 2] INSULIN >gi|11514587|... 56 6e-08
gi|208664|gb|AAA72171.1| (J02545) insulin B chain [synthetic con... 56 7e-08
gi|124683|sp||INS_SQUAC_1 [Segment 1 of 2] INSULIN 56 8e-08
gi|124557|sp||INS_BALBO_1 [Segment 1 of 2] INSULIN >gi|124562|sp... 55 1e-07
gi|1127137|pdb|1HLS|B Chain B, Nmr Structure Of The Human Insuli... 55 1e-07
gi|6573507|pdb|1B9E|B Chain B, Human Insulin Mutant Serb9glu >gi... 55 1e-07
gi|69323|pir||INCU insulin - nutria 55 1e-07
gi|115187|sp|P26736|BXD1_BOMMO BOMBYXIN D-1 PRECURSOR (BBX-D1) (... 55 2e-07
gi|1633388|pdb|1LPH|B Chain B, Lys(B28)pro(B29)-Human Insulin >g... 55 2e-07
gi|2392616|pdb|1XDA|B Chain B, Structure Of Insulin >gi|2392618|... 55 2e-07
gi|1633281|pdb|1BEN|B Chain B, Insulin Complexed With 4-Hydroxyb... 55 2e-07
gi|124626|sp||INS_HYSCR_1 [Segment 1 of 2] INSULIN 54 2e-07
gi|2116614|dbj|BAA20145.1| (AB003905) prepro-bombyxin D1'(K) [Bo... 54 2e-07
gi|124535|sp||INS_ACOCA_1 [Segment 1 of 2] INSULIN 54 2e-07
gi|124524|sp||INS2_THUTH_1 [Segment 1 of 2] INSULIN 2 54 2e-07
gi|443064|pdb|1IZB|B Chain B, Insulin Mutant With Glu B 13 Repla... 54 2e-07
gi|1431691|pdb|1MHI|B Chain B, Mol_id: 1; Molecule: Insulin; Cha... 54 2e-07
gi|780260|emb|CAA27250.1| (X03563) pot. IGF-I precursor [Homo sa... 54 2e-07
gi|124573|sp||INS_CAMDR_1 [Segment 1 of 2] INSULIN 54 2e-07
gi|4139763|pdb|1ZEH|B Chain B, Structure Of Insulin >gi|4139765|... 54 3e-07
gi|124509|sp||INS1_BATSP_1 [Segment 1 of 2] INSULIN 1 >gi|124613... 54 3e-07
gi|494172|pdb|1HIT|B Chain B, Insulin (Human) Mutant With Phe B ... 53 3e-07
gi|1334734|emb|CAA23708.1| (V00418) reading frame (part 2) [Gall... 53 3e-07
gi|230591|pdb|2INS|B Chain B, Des-Phe B1 Insulin >gi|230593|pdb|... 53 3e-07
gi|124648|sp||INS_MYOSC_1 [Segment 1 of 2] INSULIN 53 4e-07
gi|5542385|pdb|1QIZ|B Chain B, Human Insulin Hexamers With Chain... 53 4e-07
gi|1364249|emb|CAA36296.1| (X52077) insulin-like growth factor I... 53 4e-07
gi|69324|pir||INKS insulin - casiragua 53 4e-07
gi|124551|sp||INS_ANSAN_1 [Segment 1 of 2] INSULIN >gi|1699408|g... 53 4e-07
gi|124598|sp||INS_DIDMA_1 [Segment 1 of 2] INSULIN >gi|104952|pi... 53 4e-07
gi|223836|prf||1002178A insulin [Cyprinus carpio] 53 5e-07
gi|229122|prf||600165A insulin [Homo sapiens] 53 5e-07
gi|12084408|pdb|1HO0|A Chain A, New B-Chain Mutant Of Bovine Ins... 53 5e-07
gi|494168|pdb|1HIQ|B Chain B, Insulin (Human) Mutant With Phe B ... 53 5e-07
gi|124667|sp||INS_PLAFE_1 [Segment 1 of 2] INSULIN 53 5e-07
gi|124585|sp||INS_CHIBR_1 [Segment 1 of 2] INSULIN 53 6e-07
gi|6225564|sp||INS_PIAME_1 [Segment 1 of 2] INSULIN 53 6e-07
gi|2116682|dbj|BAA20092.1| (D63148) prepro-Agrius bombyxin-relat... 53 6e-07
gi|229405|prf||720921A insulin [Acomys cahirinus] 52 7e-07
gi|229103|prf||560164A insulin [Equus caballus] 52 8e-07
gi|2160512|dbj|BAA05113.1| (D26119) insulin-like growth factor-I... 52 8e-07
gi|9972743|sp|O61271|BXG1_BOMMO BOMBYXIN G-1 PRECURSOR (BBX-G1) ... 52 8e-07
gi|228833|prf||1812293B insulin:SUBUNIT=B [Anguilliformes] 52 8e-07
gi|229096|prf||550086A insulin [Sus scrofa domestica] 52 8e-07
gi|10720238|sp||INS_TRASC_1 [Segment 1 of 2] INSULIN 52 8e-07
gi|2098440|pdb|1VKS|B Chain B, Nmr Structure Of Human Insulin Mu... 52 9e-07
gi|229285|prf||690500A insulin [Lophiiformes] 52 9e-07
gi|5542387|pdb|1QIZ|D Chain D, Human Insulin Hexamers With Chain... 52 1e-06
gi|1586832|prf||2204398B insulin:SUBUNIT=B chain [Typhlonectes n... 52 1e-06
gi|229097|prf||550086B insulin [Ovis aries] 52 1e-06
gi|3913912|sp||INS_ACIGU_1 [Segment 1 of 2] INSULIN 52 1e-06
gi|1911406|gb|AAB50640.1| insulin B-chain [Tilapia nilotica=Nile... 51 1e-06
gi|229095|prf||550085A insulin [Bos taurus] 51 1e-06
gi|33021|emb|CAA27152.1| (X03420) put. IGF-I precursor (169 is 1... 51 1e-06
gi|124655|sp||INS_ONCGO_1 [Segment 1 of 2] INSULIN >gi|226149|pr... 51 1e-06
gi|84804|pir||B28986 bombyxin precursor (clone 204) - silkworm (... 51 1e-06
gi|124636|sp||INS_LEPSP_1 [Segment 1 of 2] INSULIN 51 1e-06
gi|223223|prf||0609237A insulin [Hystrix cristata] 51 2e-06
gi|12643519|sp||INS_ORNAN_1 [Segment 1 of 2] INSULIN >gi|2134450... 51 2e-06
gi|229412|prf||721138A insulin [Bauhinia purpurea] 51 2e-06
gi|124540|sp||INS_ALLMI_1 [Segment 1 of 2] INSULIN 51 2e-06
gi|6671375|gb|AAF23181.1| (AF218827) insulin-like growth factor-... 51 3e-06
gi|225727|prf||1312249A insulin [Oncorhynchus gorbuscha] 50 3e-06
gi|1246088|gb|AAB35904.1| insulin B-chain [Amphiuma tridactylum=... 50 3e-06
gi|3402072|pdb|1A7F|B Chain B, Insulin Mutant B16 Glu, B24 Gly, ... 50 3e-06
gi|1170571|sp||INS_ANGRO_1 [Segment 1 of 2] INSULIN 50 3e-06
gi|229408|prf||720927A insulin [Meleagris gallopavo] 50 3e-06
gi|1000429|gb|AAB35034.1| insulin-like growth factor II A, IGF I... 50 4e-06
gi|2981814|pdb|1SJT|B Chain B, Mini-Proinsulin, Two Chain Insuli... 50 4e-06
gi|229168|prf||640291A insulin [Balaenoptera physalus] 50 4e-06
gi|14488761|pdb|1HTV|B Chain B, Crystal Structure Of Destripepti... 50 4e-06
gi|229406|prf||720922A insulin 1 [Mus musculus] 50 4e-06
gi|124631|sp||INS_KATPE_1 [Segment 1 of 2] INSULIN 50 5e-06
gi|1311298|pdb|1MHJ|B Chain B, Mol_id: 1; Molecule: Insulin; Cha... 50 6e-06
gi|124517|sp||INS2_BATSP_1 [Segment 1 of 2] INSULIN 2 50 6e-06
gi|482673|pir||A61008 insulin-like growth factor II - sheep (fra... 50 6e-06
gi|2116678|dbj|BAA20090.1| (D63146) prepro-Agrius bombyxin-relat... 49 6e-06
gi|89870|pir||S07965 insulin-like growth factor I - sheep (fragm... 49 6e-06
gi|229407|prf||720922B insulin 2 [Mus musculus] 49 7e-06
gi|1942189|pdb|1HUI|B Chain B, Insulin Mutant (B1, B10, B16, B27... 49 8e-06
gi|4588105|gb|AAD25989.1| (AF097586) insulin-like growth factor ... 48 1e-05
gi|4376058|emb|CAA77265.1| (Y18691) insulin-like growth factor I... 48 1e-05
gi|124661|sp||INS_PETMA_1 [Segment 1 of 2] INSULIN >gi|1311695|g... 48 1e-05
gi|124545|sp||INS_AMICA_1 [Segment 1 of 2] INSULIN 48 1e-05
gi|2133946|pir||I51240 insulin-like growth factor I - chum salmo... 48 1e-05
gi|124693|sp||INS_ZAODH_1 [Segment 1 of 2] INSULIN >gi|104347|pi... 48 1e-05
gi|1842146|dbj|BAA19223.1| (AB001049) preprobombyxin F1 [Bombyx ... 48 1e-05
gi|1470095|gb|AAB05252.1| (U62106) insulin-like growth factor I ... 48 2e-05
gi|755742|emb|CAA27156.1| (X03426) put. IGF-II precursor (aa 29-... 48 2e-05
gi|1000430|gb|AAB35035.1| insulin-like growth factor II B, IGF I... 48 2e-05
gi|5107540|pdb|1BZV|B Chain B, [d-Alab26]-Des(B27-B30)-Insulin-B... 47 3e-05
gi|1942947|pdb|1PID|B Chain B, Bovine Despentapeptide Insulin >g... 47 3e-05
gi|124592|sp||INS_CROAT_1 [Segment 1 of 2] INSULIN 47 3e-05
gi|12643702|sp|P91896|BXF1_BOMMO BOMBYXIN F-1 PRECURSOR (BBX-F1)... 47 3e-05
gi|204924|gb|AAA41432.1| (M30273) insulin-like growth factor II ... 47 3e-05
gi|15212232|gb|AAK85304.1| (AY043225) insulin-like growth factor... 46 4e-05
gi|229113|prf||580107B insulin [Physeter catodon] 46 5e-05
gi|229112|prf||580107A insulin [Balaenoptera borealis] 46 6e-05
gi|213451|gb|AAA49417.1| (K01655) insulin B-chain [Oncorhynchus ... 46 7e-05
gi|229492|prf||742487A insulin [Crotalus atrox] 45 1e-04
gi|1942327|pdb|1SDB|B Chain B, Porcine Desb1-2 Despentapeptide(B... 45 2e-04
gi|13358513|ref|NP_078716.1| orf111 [lymphocystis disease virus 1] 45 2e-04
gi|85806|pir||A34049 insulin-like growth factor I' - African cla... 45 2e-04
gi|194496|gb|AAA37925.1| (M14983) insulin-like growth factor-I [... 44 2e-04
gi|10303217|emb|CAC10055.1| (Y16643) Pro-IGF-II [Myoxocephalus s... 44 2e-04
gi|1335707|emb|CAA82852.1| (Z29964) insulin related peptide, fra... 44 3e-04
gi|9973413|sp|Q9VT51|INL2_DROME PROBABLE INSULIN-LIKE PEPTIDE 2 ... 44 3e-04
gi|755741|emb|CAA27153.1| (X03421) IGF-I [Homo sapiens] 44 3e-04
gi|540508|dbj|BAA05114.1| (D26119) insulin-like growth factor-I ... 44 3e-04
gi|2147603|pir||S61360 insulin A-chain - Amphiuma tridactylum (f... 43 4e-04
gi|2392264|pdb|1DEI|B Chain B, Desheptapeptide (B24-B30) Insulin... 43 5e-04
gi|124637|sp||INS_LEPSP_2 [Segment 2 of 2] INSULIN 42 0.001
gi|225033|prf||1207048A prothoracicotropic hormone II [Bombyx mo... 41 0.001
gi|124614|sp||INS_GADCA_2 [Segment 2 of 2] INSULIN 41 0.001
gi|1911405|gb|AAB50639.1| insulin A-chain [Tilapia nilotica=Nile... 41 0.002
gi|1170572|sp||INS_ANGRO_2 [Segment 2 of 2] INSULIN >gi|6225565|... 41 0.002
gi|124541|sp||INS_ALLMI_2 [Segment 2 of 2] INSULIN >gi|10720239|... 41 0.002
gi|124525|sp||INS2_THUTH_2 [Segment 2 of 2] INSULIN 2 >gi|124656... 41 0.002
gi|3913913|sp||INS_ACIGU_2 [Segment 2 of 2] INSULIN >gi|632094|p... 41 0.002
gi|124649|sp||INS_MYOSC_2 [Segment 2 of 2] INSULIN 41 0.002
gi|4389174|pdb|1IOH|A Chain A, Insulin Mutant A8 His,(B1, B10, B... 41 0.002
gi|124662|sp||INS_PETMA_2 [Segment 2 of 2] INSULIN >gi|1311694|g... 41 0.003
gi|4376142|emb|CAA25151.1| (X00462) insulin B-chain [synthetic c... 40 0.003
gi|1699409|gb|AAB37516.1| insulin A chain [Cairina moschata=Musc... 40 0.003
gi|299299|gb|AAB25816.1| insulin A-chain [Equus przewalskii=hors... 40 0.004
gi|124510|sp||INS1_BATSP_2 [Segment 2 of 2] INSULIN 1 40 0.004
gi|124552|sp||INS_ANSAN_2 [Segment 2 of 2] INSULIN 40 0.004
gi|124643|sp||INS_MYOCO_1 [Segment 1 of 2] INSULIN 40 0.004
Sequences with E-value WORSE than threshold
gi|632093|pir||S44467 insulin I1 chain A - Polyodon spathula 40 0.005
gi|124536|sp||INS_ACOCA_2 [Segment 2 of 2] INSULIN 40 0.005
gi|124586|sp||INS_CHIBR_2 [Segment 2 of 2] INSULIN 40 0.005
gi|208662|gb|AAA72170.1| (J02544) insulin A chain [synthetic con... 40 0.006
gi|124563|sp||INS_BALPH_2 [Segment 2 of 2] INSULIN >gi|11514586|... 40 0.006
gi|229401|prf||720710A insulin [Myocastor coypus] 40 0.006
gi|124593|sp||INS_CROAT_2 [Segment 2 of 2] INSULIN 39 0.006
gi|124684|sp||INS_SQUAC_2 [Segment 2 of 2] INSULIN 39 0.007
gi|1586109|prf||2203282B insulin:SUBUNIT=B chain [Geotria austra... 39 0.008
gi|14719690|pdb|1JCA|A Chain A, Non-Standard Design Of Unstable ... 39 0.008
gi|124689|sp||INS_TORMA_2 [Segment 2 of 2] INSULIN PRECURSOR 39 0.008
gi|124694|sp||INS_ZAODH_2 [Segment 2 of 2] INSULIN 39 0.009
gi|124604|sp||INS_ELEMA_2 [Segment 2 of 2] INSULIN 39 0.009
gi|124672|sp||INS_PROGU_1 [Segment 1 of 2] INSULIN 39 0.009
gi|14488703|pdb|1J73|A Chain A, Crystal Structure Of An Unstable... 38 0.013
gi|124599|sp||INS_DIDMA_2 [Segment 2 of 2] INSULIN >gi|226296|pr... 38 0.014
gi|124518|sp||INS2_BATSP_2 [Segment 2 of 2] INSULIN 2 38 0.014
gi|1586108|prf||2203282A insulin:SUBUNIT=A chain [Geotria austra... 38 0.014
gi|929915|emb|CAA24707.1| (V01461) insulin C chain [synthetic co... 38 0.016
gi|124622|sp||INS_HYDCO_2 [Segment 2 of 2] INSULIN 38 0.018
gi|124627|sp||INS_HYSCR_2 [Segment 2 of 2] INSULIN 38 0.019
gi|12643520|sp||INS_ORNAN_2 [Segment 2 of 2] INSULIN >gi|1881820... 38 0.019
gi|127278|sp|P07223|MPI1_LYMST MOLLUSCAN INSULIN-RELATED PEPTIDE... 38 0.019
gi|124580|sp||INS_CAPHI_2 [Segment 2 of 2] INSULIN 38 0.020
gi|124558|sp||INS_BALBO_2 [Segment 2 of 2] INSULIN 38 0.020
gi|4389188|pdb|1IOG|A Chain A, Insulin Mutant A3 Gly,(B1, B10, B... 37 0.027
gi|7689351|gb|AAF67742.1| (AF254740) relaxin-like protein [Cervu... 37 0.027
gi|1431690|pdb|1MHI|A Chain A, Mol_id: 1; Molecule: Insulin; Cha... 37 0.027
gi|124574|sp||INS_CAMDR_2 [Segment 2 of 2] INSULIN >gi|1942946|p... 37 0.030
gi|84754|pir||JT0412 bombyxin-IV chain B - silkworm 37 0.037
gi|454239|emb|CAA82851.1| (Z29963) insulin related peptide, frag... 36 0.044
gi|124546|sp||INS_AMICA_2 [Segment 2 of 2] INSULIN 36 0.045
gi|226246|prf||1503112B bombyxin IV B [Bombyx mori] 36 0.047
gi|99035|pir||S19631 ribosomal protein AT-L30 - Microtetraspora ... 36 0.048
gi|1709087|sp|P80090|MPI3_LYMST MOLLUSCAN INSULIN-RELATED PEPTID... 36 0.057
gi|625940|pir||A61576 insulin-like growth factor I - unidentifie... 36 0.071
gi|124644|sp||INS_MYOCO_2 [Segment 2 of 2] INSULIN 36 0.072
gi|124673|sp||INS_PROGU_2 [Segment 2 of 2] INSULIN 36 0.085
gi|124609|sp||INS_FELCA_2 [Segment 2 of 2] INSULIN 35 0.10
Alignments
>gi|4557671|ref|NP_000198.1| proinsulin precursor [Homo sapiens]
gi|14773144|ref|XP_028180.1| proinsulin precursor [Homo sapiens]
gi|124617|sp|P01308|INS_HUMAN INSULIN PRECURSOR
gi|69300|pir||IPHU insulin precursor - human
gi|386828|gb|AAA59172.1| (J00268) insulin [Homo sapiens]
gi|386829|gb|AAA59173.1| (M10039) insulin [Homo sapiens]
gi|394766|emb|CAA49913.1| (X70508) pre-proinsulin [Homo sapiens]
gi|758088|emb|CAA23828.1| (V00565) preproinsulin [Homo sapiens]
gi|13528924|gb|AAH05255.1|AAH05255 (BC005255) insulin [Homo sapiens]
gi|223160|prf||0601246A insulin,prepro [Homo sapiens]
Length = 110
Score = 143 bits (361), Expect = 2e-34
Identities = 110/110 (100%), Positives = 110/110 (100%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED
Sbjct: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|266373|sp|P30406|INS_MACFA INSULIN PRECURSOR
gi|86627|pir||JQ0178 insulin precursor - crab-eating macaque
gi|342122|gb|AAA36849.1| (J00336) preproinsulin [Macaca fascicularis]
Length = 110
Score = 143 bits (360), Expect = 3e-34
Identities = 108/110 (98%), Positives = 108/110 (98%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMRLLPLLALLALWGPDPA AFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED
Sbjct: 1 MALWMRLLPLLALLALWGPDPAPAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 PQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|266377|sp|P30410|INS_PANTR INSULIN PRECURSOR
gi|283944|pir||A42179 insulin precursor - chimpanzee
gi|38252|emb|CAA43403.1| (X61089) Preproinsulin [Pan troglodytes]
Length = 110
Score = 142 bits (359), Expect = 5e-34
Identities = 108/110 (98%), Positives = 109/110 (98%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMRLLPLL LLALWGPDPA+AFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED
Sbjct: 1 MALWMRLLPLLVLLALWGPDPASAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|9506815|ref|NP_062002.1| insulin [Rattus norvegicus]
gi|124512|sp|P01322|INS1_RAT INSULIN 1 PRECURSOR
gi|69314|pir||IPRT1 insulin 1 precursor - rat
gi|56488|emb|CAA24559.1| (V01242) insulin I [Rattus norvegicus]
gi|204948|gb|AAA41439.1| (M25584) insulin 1 [Rattus norvegicus]
gi|204957|gb|AAA41442.1| (J00747) preproinsulin I [Rattus norvegicus]
Length = 110
Score = 142 bits (358), Expect = 6e-34
Identities = 91/110 (82%), Positives = 95/110 (85%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMR LPLLALL LW P PA AFV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED
Sbjct: 1 MALWMRFLPLLALLVLWEPKPAQAFVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q+ELGGGP AG LQ LALE + QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 PQVPQLELGGGPEAGDLQTLALEVARQKRGIVDQCCTSICSLYQLENYCN 110
>gi|266362|sp|P30407|INS_CERAE INSULIN PRECURSOR
gi|283935|pir||B42179 insulin precursor - green monkey
gi|22809|emb|CAA43405.1| (X61092) Preproinsulin [Cercopithecus aethiops]
Length = 110
Score = 141 bits (357), Expect = 8e-34
Identities = 107/110 (97%), Positives = 107/110 (97%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMRLLPLLALLALWGPDP AFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED
Sbjct: 1 MALWMRLLPLLALLALWGPDPVPAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 PQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
>gi|124588|sp|P01313|INS_CRILO INSULIN PRECURSOR
gi|2137094|pir||I48166 insulin precursor - golden hamster
gi|305360|gb|AAA37089.1| (M26328) preproinsulin [Mesocricetus auratus]
Length = 110
Score = 141 bits (357), Expect = 8e-34
Identities = 91/110 (82%), Positives = 96/110 (86%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M LWMRLLPLL LL LW P+PA AFVNQHLCGSHLVEALYLVCGERGFFYTPK+RR ED
Sbjct: 1 MTLWMRLLPLLTLLVLWEPNPAQAFVNQHLCGSHLVEALYLVCGERGFFYTPKSRRGVED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q+ELGGGPGA LQ LALE + QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 PQVAQLELGGGPGADDLQTLALEVAQQKRGIVDQCCTSICSLYQLENYCN 110
>gi|2497407|sp|Q62587|INS_PSAOB INSULIN PRECURSOR
gi|1370283|emb|CAA66897.1| (X98241) preproinsulin [Psammomys obesus]
Length = 110
Score = 140 bits (352), Expect = 3e-33
Identities = 89/110 (80%), Positives = 94/110 (84%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMRLLPLLA L LW P PA AFVNQHLCGSHLVEALYLVCGERGFFYTPK RR +D
Sbjct: 1 MALWMRLLPLLAFLILWEPSPAHAFVNQHLCGSHLVEALYLVCGERGFFYTPKFRRGVDD 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
Q+ Q+ELGG PGAG L+ LALE + QKRGIVEQCCT ICSLYQLENYCN
Sbjct: 61 PQMPQLELGGSPGAGDLRALALEVARQKRGIVEQCCTGICSLYQLENYCN 110
>gi|9506817|ref|NP_062003.1| insulin 2 [Rattus norvegicus]
gi|124520|sp|P01323|INS2_RAT INSULIN 2 PRECURSOR
gi|69315|pir||IPRT2 insulin 2 precursor - rat
gi|56490|emb|CAA24560.1| (V01243) preproinsulin [Rattus norvegicus]
gi|204952|gb|AAA41440.1| (M25585) insulin 2 [Rattus norvegicus]
gi|204959|gb|AAA41443.1| (J00748) preproinsulin II [Rattus norvegicus]
Length = 110
Score = 139 bits (351), Expect = 4e-33
Identities = 91/110 (82%), Positives = 96/110 (86%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW+R LPLLALL LW P PA AFV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED
Sbjct: 1 MALWIRFLPLLALLILWEPRPAQAFVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q+ELGGGPGAG LQ LALE + QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 PQVAQLELGGGPGAGDLQTLALEVARQKRGIVDQCCTSICSLYQLENYCN 110
>gi|6680463|ref|NP_032413.1| insulin II [Mus musculus]
gi|124519|sp|P01326|INS2_MOUSE INSULIN 2 PRECURSOR
gi|625280|pir||INMS2 insulin 2 precursor - mouse
gi|52715|emb|CAA28433.1| (X04724) preproinsulin II [Mus musculus]
gi|12841261|dbj|BAB25135.1| (AK007612) putative [Mus musculus]
gi|744259|prf||2014276B insulin [Mus musculus]
Length = 110
Score = 138 bits (347), Expect = 1e-32
Identities = 90/110 (81%), Positives = 94/110 (84%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMR LPLLALL LW P AFV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED
Sbjct: 1 MALWMRFLPLLALLFLWESHPTQAFVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q+ELGGGPGAG LQ LALE + QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 PQVAQLELGGGPGAGDLQTLALEVAQQKRGIVDQCCTSICSLYQLENYCN 110
>gi|307072|gb|AAA59179.1| (L15440) insulin [Homo sapiens]
Length = 107
Score = 135 bits (339), Expect = 9e-32
Identities = 107/110 (97%), Positives = 107/110 (97%), Gaps = 3/110 (2%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE
Sbjct: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE- 59
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 60 --VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 107
>gi|124587|sp|P01332|INS_CHICK INSULIN PRECURSOR
gi|69325|pir||IPCH insulin precursor - chicken
gi|212212|gb|AAA48925.1| (J00874) preproinsulin (second expressed [Gallus gallus]
gi|853836|emb|CAA41738.1| (X58993) preproinsulin [Gallus gallus]
Length = 107
Score = 133 bits (335), Expect = 3e-31
Identities = 70/110 (63%), Positives = 75/110 (67%), Gaps = 3/110 (2%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW+R LPLLALL GP + A NQHLCGSHLVEALYLVCGERGFFY+PK RR+ E
Sbjct: 1 MALWIRSLPLLALLVFSGPGTSYAAANQHLCGSHLVEALYLVCGERGFFYSPKARRDVEQ 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
V G AG L E KRGIVEQCC + CSLYQLENYCN
Sbjct: 61 PLVSSPLRG---EAGVLPFQQEEYEKVKRGIVEQCCHNTCSLYQLENYCN 107
>gi|208668|gb|AAA72172.1| (J02547) synthetic preproinsulin [synthetic construct]
Length = 114
Score = 133 bits (334), Expect = 4e-31
Identities = 106/114 (92%), Positives = 108/114 (93%), Gaps = 4/114 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAA----FVNQHLCGSHLVEALYLVCGERGFFYTPKTRR 56
M LW+RLLPL+ALL LWGPDPAAA FVNQHLCGSHLVEALYLVCGERGFFYTPKTRR
Sbjct: 1 MGLWIRLLPLIALLILWGPDPAAAEFRMFVNQHLCGSHLVEALYLVCGERGFFYTPKTRR 60
Query: 57 EAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 EAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 114
>gi|124575|sp|P01321|INS_CANFA INSULIN PRECURSOR
gi|69312|pir||IPDG insulin precursor - dog
gi|995|emb|CAA23475.1| (V00179) preproinsulin [Canis sp.]
Length = 110
Score = 130 bits (327), Expect = 2e-30
Identities = 97/110 (88%), Positives = 98/110 (88%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWMRLLPLLALLALW P P AFVNQHLCGSHLVEALYLVCGERGFFYTPK RRE ED
Sbjct: 1 MALWMRLLPLLALLALWAPAPTRAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
LQV VEL G PG G LQPLALEG+LQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 LQVRDVELAGAPGEGGLQPLALEGALQKRGIVEQCCTSICSLYQLENYCN 110
>gi|6680461|ref|NP_032412.1| insulin I [Mus musculus]
gi|124511|sp|P01325|INS1_MOUSE INSULIN 1 PRECURSOR
gi|625279|pir||INMS1 insulin 1 precursor - mouse
gi|52713|emb|CAA28434.1| (X04725) preproinsulin I (AA 1-108) [Mus musculus]
gi|12840833|dbj|BAB24974.1| (AK007345) putative [Mus musculus]
gi|12842500|dbj|BAB25628.1| (AK008358) putative [Mus musculus]
gi|744258|prf||2014276A insulin [Mus musculus]
Length = 108
Score = 127 bits (320), Expect = 1e-29
Identities = 86/110 (78%), Positives = 91/110 (82%), Gaps = 2/110 (1%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MAL + LPLLALLALW P P AFV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED
Sbjct: 1 MALLVHFLPLLALLALWEPKPTQAFVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q+ELGG PG LQ LALE + QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 PQVEQLELGGSPG--DLQTLALEVARQKRGIVDQCCTSICSLYQLENYCN 108
>gi|124553|sp|P10604|INS_AOTTR INSULIN PRECURSOR
gi|104987|pir||A39883 insulin precursor - douroucouli
gi|176556|gb|AAA35374.1| (J02989) preproinsulin [Aotus trivirgatus]
Length = 108
Score = 127 bits (320), Expect = 2e-29
Identities = 94/110 (85%), Positives = 99/110 (89%), Gaps = 2/110 (1%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWM LLPLLALLALWGP+PA AFVNQHLCG HLVEALYLVCGERGFFY PKTRREAED
Sbjct: 1 MALWMHLLPLLALLALWGPEPAPAFVNQHLCGPHLVEALYLVCGERGFFYAPKTRREAED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
LQVGQVELGGG GSL P LEG +QKRG+V+QCCTSICSLYQL+NYCN
Sbjct: 61 LQVGQVELGGGSITGSLPP--LEGPMQKRGVVDQCCTSICSLYQLQNYCN 108
>gi|124526|sp|P12707|INS2_XENLA INSULIN 2 PRECURSOR
gi|69333|pir||IPXL2 insulin II precursor - African clawed frog
gi|214535|gb|AAA49887.1| (M24442) preproinsulin II [Xenopus laevis]
Length = 106
Score = 126 bits (318), Expect = 3e-29
Identities = 62/110 (56%), Positives = 72/110 (65%), Gaps = 4/110 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWM+ LPL+ +L P+ A NQHLCGSHLVEALYLVCG+RGFFY PK +R+ E
Sbjct: 1 MALWMQCLPLVLVLLFSTPNT-EALANQHLCGSHLVEALYLVCGDRGFFYYPKIKRDIEQ 59
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV + +Q E KRGIVEQCC S CSL+QLENYCN
Sbjct: 60 AQVNGPQDN---ELDGMQFQPQEYQKMKRGIVEQCCHSTCSLFQLENYCN 106
>gi|12841054|dbj|BAB25058.1| (AK007482) putative [Mus musculus]
Length = 108
Score = 126 bits (317), Expect = 3e-29
Identities = 85/110 (77%), Positives = 91/110 (82%), Gaps = 2/110 (1%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MAL + LPLLALLALW P P AFV QHLCG HLV+ALYLVCGERGFFYTPK+RRE ED
Sbjct: 1 MALLVHFLPLLALLALWEPKPTQAFVKQHLCGPHLVKALYLVCGERGFFYTPKSRREVED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q+ELGG PG LQ LALE + QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 PQVEQLELGGSPG--DLQTLALEVARQKRGIVDQCCTSICSLYQLENYCN 108
>gi|223965|prf||1006230A insulin,pro- [Macaca mulatta]
Length = 86
Score = 125 bits (314), Expect = 8e-29
Identities = 85/86 (98%), Positives = 85/86 (98%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEG
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEG 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 SLQKRGIVEQCCTSICSLYQLENYCN 86
>gi|12644021|sp|P81025|INS_ORENI INSULIN PRECURSOR
gi|4558782|gb|AAD22742.1| (AF038123) insulin precursor [Oreochromis niloticus]
Length = 113
Score = 125 bits (313), Expect = 1e-28
Identities = 50/113 (44%), Positives = 65/113 (57%), Gaps = 6/113 (5%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
ALW++ LL L+ + P A QHLCGSHLV+ALYLVCG+RGFFY P RR+ + L
Sbjct: 3 ALWLQAFSLLVLMMVSWPGSQAVGGPQHLCGSHLVDALYLVCGDRGFFYNP--RRDVDPL 60
Query: 62 QVGQVELGGG----PGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
GG G + + KRGIVE+CC C+++ L+NYCN
Sbjct: 61 LGFLPPKAGGAVVQGGENEVTFKDQMEMMVKRGIVEECCHKPCTIFDLQNYCN 113
>gi|58103|emb|CAA23424.1| (V00082) reading frame proinsulin [synthetic construct]
gi|208670|gb|AAA72531.1| (M12913) proinsulin [synthetic construct]
Length = 87
Score = 124 bits (311), Expect = 1e-28
Identities = 86/86 (100%), Positives = 86/86 (100%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG
Sbjct: 2 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 61
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
SLQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 62 SLQKRGIVEQCCTSICSLYQLENYCN 87
>gi|124594|sp|P01335|INS_CYPCA INSULIN PRECURSOR
gi|69334|pir||IPCA insulin precursor - common carp
gi|62628|emb|CAA25496.1| (X00989) preproinsulin [Cyprinus carpio]
gi|224208|prf||1012233A insulin,prepro [Cyprinus carpio]
Length = 108
Score = 124 bits (311), Expect = 2e-28
Identities = 49/111 (44%), Positives = 64/111 (57%), Gaps = 4/111 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA+W++ LL LLA+ + A A QHLCGSHLV+ALYLVCG GFFY PK R+ +
Sbjct: 1 MAVWIQAGALLFLLAVSSVN-ANAGAPQHLCGSHLVDALYLVCGPTGFFYNPK--RDVDP 57
Query: 61 LQVGQVELGGGPGAGSLQPLALEGS-LQKRGIVEQCCTSICSLYQLENYCN 110
+ ++KRGIVEQCC CS+++L+NYCN
Sbjct: 58 PLGFLPPKSAQETEVADFAFKDHAEVIRKRGIVEQCCHKPCSIFELQNYCN 108
>gi|229391|prf||720460A insulin 1,pro [Rattus norvegicus]
Length = 86
Score = 123 bits (310), Expect = 2e-28
Identities = 72/86 (83%), Positives = 76/86 (87%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCG HLVEALYLVCGERGFFYTPK+RRE ED QV Q+ELGGGP AG LQ LALE
Sbjct: 1 FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVPQLELGGGPEAGDLQTLALEV 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 ARQKRGIVDQCCTSICSLYQLENYCN 86
>gi|229392|prf||720460B insulin 2,pro [Rattus norvegicus]
Length = 86
Score = 123 bits (310), Expect = 2e-28
Identities = 73/86 (84%), Positives = 77/86 (88%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FV QHLCGSHLVEALYLVCGERGFFYTP +RRE ED QV Q+ELGGGPGAG LQ LALE
Sbjct: 1 FVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVPQLELGGGPGAGDLQTLALEV 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+ QKRGIV+QCCTSICSLYQLENYCN
Sbjct: 61 ARQKRGIVDQCCTSICSLYQLENYCN 86
>gi|14906249|gb|AAK72558.1| (AY038604) insulin [Spermophilus tridecemlineatus]
Length = 110
Score = 122 bits (307), Expect = 5e-28
Identities = 98/110 (89%), Positives = 101/110 (91%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW RLLPLLALLAL GPDPA AFVNQHLCGSHLVEALYLVCGERGFFYTPK+RRE E+
Sbjct: 1 MALWTRLLPLLALLALLGPDPAQAFVNQHLCGSHLVEALYLVCGERGFFYTPKSRREVEE 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
Q GQVELGGGPGAG QPLALE +LQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 QQGGQVELGGGPGAGLPQPLALEMALQKRGIVEQCCTSICSLYQLENYCN 110
>gi|124513|sp|P12706|INS1_XENLA INSULIN 1 PRECURSOR
gi|69332|pir||IPXL1 insulin I precursor - African clawed frog
gi|214537|gb|AAA49888.1| (M24443) preproinsulin I [Xenopus laevis]
Length = 106
Score = 122 bits (306), Expect = 6e-28
Identities = 61/110 (55%), Positives = 72/110 (65%), Gaps = 4/110 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWM+ LPL+ +L P+ A VNQHLCGSHLVEALYLVCG+RGFFY PK +R+ E
Sbjct: 1 MALWMQCLPLVLVLFFSTPNT-EALVNQHLCGSHLVEALYLVCGDRGFFYYPKVKRDMEQ 59
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
V + +Q E KRGIVEQCC S CSL+QLE+YCN
Sbjct: 60 ALVSGPQDN---ELDGMQLQPQEYQKMKRGIVEQCCHSTCSLFQLESYCN 106
>gi|13517225|gb|AAK28712.1| (AF199588) preproinsulin [Pantodon buchholzi]
Length = 110
Score = 121 bits (304), Expect = 1e-27
Identities = 53/111 (47%), Positives = 68/111 (60%), Gaps = 2/111 (1%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW++ LL LL L P +A +QHLCGSHLV+ALY+VCGE+GFFY PKT+R+ +
Sbjct: 1 MALWLQAFTLLVLLVLSSPGAQSA-SSQHLCGSHLVDALYMVCGEKGFFYQPKTKRDVDP 59
Query: 61 LQVGQVELGGGPGAGSLQPLALEGS-LQKRGIVEQCCTSICSLYQLENYCN 110
L P +G KRGIVEQCC C+++ L+NYCN
Sbjct: 60 LLGFLSPKSAQENEADEYPYKDQGDLKVKRGIVEQCCHHPCNIFDLQNYCN 110
>gi|13991923|gb|AAK51558.1|AF373021_1 (AF373021) preproinsulin [Catla catla]
Length = 108
Score = 121 bits (303), Expect = 1e-27
Identities = 49/111 (44%), Positives = 64/111 (57%), Gaps = 4/111 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA+W++ LL LLA+ + A QHLCGSHLV+ALYLVCG GFFY PK R+ +
Sbjct: 1 MAVWLQAGALLFLLAVSSVN-ANPGAPQHLCGSHLVDALYLVCGPTGFFYNPK--RDVDP 57
Query: 61 LQVGQVELGGGPGAGSLQPLALEGS-LQKRGIVEQCCTSICSLYQLENYCN 110
L + ++KRGIVEQCC CS+++L+NYCN
Sbjct: 58 LMGFLPPKSAQETEVADFAFKDHAEVIRKRGIVEQCCHKPCSIFELQNYCN 108
>gi|13517219|gb|AAK28709.1| (AF199585) preproinsulin [Catostomus commersoni]
Length = 108
Score = 120 bits (301), Expect = 2e-27
Identities = 51/111 (45%), Positives = 64/111 (56%), Gaps = 4/111 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA+W++ LL LLA+ G + A QHLCGSHLV+ALYLVCG GFFY PK R+ +
Sbjct: 1 MAVWLQAGALLFLLAVSGVN-ANGVAPQHLCGSHLVDALYLVCGPTGFFYNPK--RDVDP 57
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSL-QKRGIVEQCCTSICSLYQLENYCN 110
L G + L +KRGIVEQCC C+++ LE YCN
Sbjct: 58 LIGFLPPKSGPENEVADFAFKDHAELIRKRGIVEQCCHRPCNIFDLEKYCN 108
>gi|124638|sp|P01341|INS_LOPPI INSULIN PRECURSOR
gi|69346|pir||IPAF insulin precursor - American goosefish
gi|64026|emb|CAA23907.1| (V00634) reading frame preproinsulin [Lophius americanus]
Length = 116
Score = 120 bits (301), Expect = 3e-27
Identities = 51/116 (43%), Positives = 63/116 (53%), Gaps = 9/116 (7%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
ALW++ LL LL + P A QHLCGSHLV+ALYLVCG+RGFFY PK R+ + L
Sbjct: 3 ALWLQSFSLLVLLVVSWPGSQAVAPAQHLCGSHLVDALYLVCGDRGFFYNPK--RDVDQL 60
Query: 62 QVGQVELGGGP-------GAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
GG + KRGIVEQCC C+++ L+NYCN
Sbjct: 61 LGFLPPKSGGAAAAGADNEVAEFAFKDQMEMMVKRGIVEQCCHRPCNIFDLQNYCN 116
>gi|14161273|gb|AAK54684.1| (AF282408) preproinsulin [Hiodon alosoides]
Length = 110
Score = 120 bits (300), Expect = 3e-27
Identities = 52/111 (46%), Positives = 66/111 (58%), Gaps = 2/111 (1%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW++ LL LL L P +A +QHLCGSHLV+ALY+VCGE+GFFY PKT+R+ +
Sbjct: 1 MALWLQAFTLLVLLVLSSPGAQSA-SSQHLCGSHLVDALYMVCGEKGFFYQPKTKRDVDP 59
Query: 61 LQVGQVELGGGPGAGSLQPLALEGS-LQKRGIVEQCCTSICSLYQLENYCN 110
L P +G KRGIVEQCC C+++ L YCN
Sbjct: 60 LLGFLSPKSAQENEADEYPYKDQGDLKVKRGIVEQCCHRPCNIFDLNQYCN 110
>gi|9408409|gb|AAF87285.1|AF227187_1 (AF227187) preproinsulin [Rana pipiens]
Length = 106
Score = 116 bits (292), Expect = 3e-26
Identities = 56/110 (50%), Positives = 73/110 (65%), Gaps = 4/110 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW++ L + LL+L+ P F NQ+LCGSHLVEALY+VCG+RGFFY+P++RR+ E
Sbjct: 1 MALWIQCLHIAVLLSLFTP-TLKTFDNQYLCGSHLVEALYMVCGDRGFFYSPRSRRDLEQ 59
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
V + G +Q + +K GIVEQCC + CSLY LENYCN
Sbjct: 60 PLVNGL---QGSELDEMQVQSQAFQKRKPGIVEQCCHNTCSLYDLENYCN 106
>gi|13517227|gb|AAK28713.1| (AF199589) preproinsulin [Osteoglossum bicirrhosum]
Length = 111
Score = 116 bits (290), Expect = 4e-26
Identities = 55/111 (49%), Positives = 70/111 (62%), Gaps = 1/111 (0%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA+W++ PLL LL L A + +Q LCGSHLV+ALY+VCG+RGFFY+PK+RREAE
Sbjct: 1 MAIWLQAFPLLVLLVLSSSPGAESSSSQRLCGSHLVDALYMVCGDRGFFYSPKSRREAEP 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGS-LQKRGIVEQCCTSICSLYQLENYCN 110
L G P +G KRGIVEQCC C+++ L+NYCN
Sbjct: 61 LLGFLSPKSGQENEVDEYPYKEQGELKVKRGIVEQCCHRPCNIFDLQNYCN 111
>gi|9973534|sp|Q9W7R2|INS_VERMO INSULIN PRECURSOR
gi|5381267|dbj|BAA82315.1| (AB029318) preproinsulin [Verasper moseri]
Length = 115
Score = 115 bits (287), Expect = 1e-25
Identities = 49/115 (42%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
ALW++ + LL L+ + A QHLCG+HLV+ALYLVCGERGFFYTPK R+ + L
Sbjct: 3 ALWLQSVSLLVLMLVSWSGSQAVLPPQHLCGAHLVDALYLVCGERGFFYTPK--RDVDPL 60
Query: 62 QVGQVELG------GGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
G + KRGIVEQCC C+++ L+NYCN
Sbjct: 61 LGFLPAKSGGAAAGGENEVAEFAFKDQMEMMVKRGIVEQCCHKPCNIFDLQNYCN 115
>gi|124581|sp|P01329|INS_CAVPO INSULIN PRECURSOR
gi|69322|pir||IPGP insulin precursor - guinea pig
gi|305337|gb|AAA37042.1| (M11713) preproinsulin [Cavia porcellus]
Length = 110
Score = 114 bits (286), Expect = 1e-25
Identities = 76/110 (69%), Positives = 88/110 (79%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWM LL +LALLALWGP+ AFV++HLCGS+LVE LY VC + GFFY PK RRE ED
Sbjct: 1 MALWMHLLTVLALLALWGPNTGQAFVSRHLCGSNLVETLYSVCQDDGFFYIPKDRRELED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q ELG G GAG LQPLALE +LQKRGIV+QCCT C+ +QL++YCN
Sbjct: 61 PQVEQTELGMGLGAGGLQPLALEMALQKRGIVDQCCTGTCTRHQLQSYCN 110
>gi|1708499|sp|P51463|INS_SELRF INSULIN PRECURSOR
gi|2147962|pir||I51221 insulin precursor - Selaphorus rufus (fragment)
gi|451262|gb|AAC64211.1| (S66612) preproinsulin [Selasphorus rufus]
Length = 103
Score = 114 bits (285), Expect = 2e-25
Identities = 68/106 (64%), Positives = 74/106 (69%), Gaps = 3/106 (2%)
Query: 5 MRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVG 64
++ LPLLALLAL GP + A VNQHLCGSHLVEALYLVCGERGFFY+PK RR+AE V
Sbjct: 1 IQSLPLLALLALSGPGTSHAAVNQHLCGSHLVEALYLVCGERGFFYSPKARRDAEHPLVN 60
Query: 65 QVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
G G L E KRGIVEQCC + CSLYQLENYCN
Sbjct: 61 GPLHG---EVGDLPFQQEEFEKVKRGIVEQCCHNTCSLYQLENYCN 103
>gi|387059|gb|AAA37041.1| (K02233) insulin [Cavia porcellus]
Length = 110
Score = 114 bits (285), Expect = 2e-25
Identities = 76/110 (69%), Positives = 88/110 (79%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALWM LL +LALLALWGP+ AFV++HLCGS+LVE LY VC + GFFY PK RRE ED
Sbjct: 1 MALWMHLLTVLALLALWGPNTNQAFVSRHLCGSNLVETLYSVCQDDGFFYIPKDRRELED 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QV Q ELG G GAG LQPLALE +LQKRGIV+QCCT C+ +QL++YCN
Sbjct: 61 PQVEQTELGMGLGAGGLQPLALEMALQKRGIVDQCCTGTCTRHQLQSYCN 110
>gi|13517221|gb|AAK28710.1| (AF199586) preproinsulin [Chitala chitala]
Length = 111
Score = 113 bits (283), Expect = 3e-25
Identities = 57/112 (50%), Positives = 66/112 (58%), Gaps = 3/112 (2%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPK-TRREAE 59
MA+W+R LL LL + P A A NQHLCGSHLVEALYLVCGERGFFY PK +R+AE
Sbjct: 1 MAVWLRAFSLLVLLVVSSPG-ANAASNQHLCGSHLVEALYLVCGERGFFYNPKMDKRDAE 59
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGS-LQKRGIVEQCCTSICSLYQLENYCN 110
L G P +G KRGIVEQCC C+++ YCN
Sbjct: 60 PLLGFLSPKSGLENEVDEYPFKDQGDVKMKRGIVEQCCHRPCNIFDQNQYCN 111
>gi|1352467|sp|P01311|INS_RABIT INSULIN PRECURSOR
gi|1083159|pir||A53438 insulin precursor - rabbit
gi|7428584|pir||INRB insulin precursor - rabbit
gi|467971|gb|AAA19033.1| (U03610) insulin [Oryctolagus cuniculus]
Length = 110
Score = 111 bits (278), Expect = 1e-24
Identities = 93/110 (84%), Positives = 96/110 (86%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA LLPLLALL L DPA AFVNQHLCGSHLVEALYLVCGERGFFYTPK+RRE E+
Sbjct: 1 MASLAALLPLLALLVLCRLDPAQAFVNQHLCGSHLVEALYLVCGERGFFYTPKSRREVEE 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
LQVGQ ELGGGPGAG LQP ALE +LQKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 LQVGQAELGGGPGAGGLQPSALELALQKRGIVEQCCTSICSLYQLENYCN 110
>gi|12053668|emb|CAC20109.1| (AJ237750) insulin [Danio rerio]
Length = 108
Score = 109 bits (272), Expect = 6e-24
Identities = 49/111 (44%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA+W++ LL LL + QHLCGSHLV+ALYLVCG GFFY PK R+ E
Sbjct: 1 MAVWIQAGALLVLLVVSSVST-NPGTPQHLCGSHLVDALYLVCGPTGFFYNPK--RDVEP 57
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSL-QKRGIVEQCCTSICSLYQLENYCN 110
L + L +KRGIVEQCC CS+++L+NYCN
Sbjct: 58 LLGFLPPKSAQETEVADFAFKDHAELIRKRGIVEQCCHKPCSIFELQNYCN 108
>gi|124651|sp|P17715|INS_OCTDE INSULIN PRECURSOR
gi|538567|pir||IPRTDU insulin precursor - degu
gi|202472|gb|AAA40590.1| (M57671) insulin [Octodon degus]
Length = 109
Score = 108 bits (270), Expect = 9e-24
Identities = 72/110 (65%), Positives = 82/110 (74%), Gaps = 3/110 (2%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA WM LL +LALLALWGP+ A+ +QHLCGS+LVEALY+ CG GF Y P RRE ED
Sbjct: 1 MAPWMHLLTVLALLALWGPNSVQAYSSQHLCGSNLVEALYMTCGRSGF-YRPHDRRELED 59
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
LQV Q EL G AG LQP ALE LQKRGIV+QCC +IC+ QL+NYCN
Sbjct: 60 LQVEQAEL--GLEAGGLQPSALEMILQKRGIVDQCCNNICTFNQLQNYCN 107
>gi|9973509|sp|O73727|INS_BRARE INSULIN PRECURSOR
gi|2935704|gb|AAC41261.1| (AF036326) preproinsulin [Danio rerio]
Length = 108
Score = 108 bits (269), Expect = 1e-23
Identities = 49/111 (44%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA+W++ LL LL + QHLCGSHLV+ALYLVCG GFFY PK R+ E
Sbjct: 1 MAVWLQAGALLVLLVVSSVST-NPGTPQHLCGSHLVDALYLVCGPTGFFYNPK--RDVEP 57
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSL-QKRGIVEQCCTSICSLYQLENYCN 110
L + L +KRGIVEQCC CS+++L+NYCN
Sbjct: 58 LLGFLPPKSAQETEVADFAFKDHAELIRKRGIVEQCCHKPCSIFELQNYCN 108
>gi|3885494|gb|AAC77920.1| (AF064555) preproinsulin [Sus scrofa]
Length = 127
Score = 107 bits (267), Expect = 2e-23
Identities = 92/110 (83%), Positives = 93/110 (83%), Gaps = 2/110 (1%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW RLLPLLALLALW P PA AFVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+
Sbjct: 20 MALWTRLLPLLALLALWAPAPAQAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREAEN 79
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
Q G VE G G G LQ LALEG QKRGIVEQCCTSICSLYQLENYCN
Sbjct: 80 PQAGAVE--LGGGLGGLQALALEGPPQKRGIVEQCCTSICSLYQLENYCN 127
>gi|12643972|sp|P01315|INS_PIG INSULIN PRECURSOR
Length = 108
Score = 106 bits (266), Expect = 3e-23
Identities = 92/110 (83%), Positives = 93/110 (83%), Gaps = 2/110 (1%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW RLLPLLALLALW P PA AFVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+
Sbjct: 1 MALWTRLLPLLALLALWAPAPAQAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREAEN 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
Q G VE G G G LQ LALEG QKRGIVEQCCTSICSLYQLENYCN
Sbjct: 61 PQAGAVE--LGGGLGGLQALALEGPPQKRGIVEQCCTSICSLYQLENYCN 108
>gi|2135482|pir||I76705 insulin-like growth factor II precursor - human
gi|183122|gb|AAA52544.1| (M29645) insulin-like growth factor II precursor [Homo sapiens]
Length = 180
Score = 105 bits (262), Expect = 8e-23
Identities = 35/109 (32%), Positives = 46/109 (42%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M + +L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 3 MPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR---- 58
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 59 -----------------------VSRRSRGIVEECCFRSCDLALLETYC 84
>gi|124615|sp|P21563|INS_RODSP INSULIN PRECURSOR
gi|102414|pir||S09278 insulin precursor - Geodia cydonium
Length = 108
Score = 105 bits (261), Expect = 9e-23
Identities = 86/111 (77%), Positives = 90/111 (80%), Gaps = 4/111 (3%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALY-LVCGERGFFYTPKTRREAE 59
M LLPLLALL LWGPDPA AFVNQHLCGSHLVEALY LVCGERGFFYTP +RRE E
Sbjct: 1 M-ALWILLPLLALLILWGPDPAQAFVNQHLCGSHLVEALYILVCGERGFFYTPMSRREVE 59
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
D QVGQVELG GPGAGS Q LALE + Q R IV+QC + ICSLYQ ENYCN
Sbjct: 60 DPQVGQVELGAGPGAGSEQTLALEVARQAR-IVQQCTSGICSLYQ-ENYCN 108
>gi|13517223|gb|AAK28711.1| (AF199587) preproinsulin [Gnathonemus petersii]
Length = 87
Score = 105 bits (261), Expect = 1e-22
Identities = 40/86 (46%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
QHLCGSHLVEAL+LVCGERGFF+ P T+R+ + L G +
Sbjct: 2 PAQHLCGSHLVEALFLVCGERGFFFNPDTKRDVDSLLGFLSPKSGPENEADEYRYKEQAE 61
Query: 86 -LQKRGIVEQCCTSICSLYQLENYCN 110
KRGIVEQCC C+++ L YCN
Sbjct: 62 VKVKRGIVEQCCHHPCNIFDLNQYCN 87
>gi|213445|gb|AAA49414.1| (J00936) preproinsulin [Oncorhynchus keta]
gi|223664|prf||0906264A insulin,prepro [Oncorhynchus keta]
Length = 105
Score = 104 bits (259), Expect = 2e-22
Identities = 50/110 (45%), Positives = 60/110 (54%), Gaps = 5/110 (4%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW L L+ L A QHLCGSHLV+ALYLVCGE+GFFYTPK R+ +
Sbjct: 1 MALW--LQAASLLVLLALSPGVDAAAAQHLCGSHLVDALYLVCGEKGFFYTPK--RDVDP 56
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
L E + KRGIVEQCC C+++ L+NYCN
Sbjct: 57 LIGFLSPKSAKENEEYPFKDQTEM-MVKRGIVEQCCHRPCNIFDLQNYCN 105
>gi|87954|pir||S02423 insulin-like growth factor II precursor, splice form II - human
Length = 183
Score = 103 bits (257), Expect = 3e-22
Identities = 35/108 (32%), Positives = 45/108 (41%), Gaps = 24/108 (22%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VCG+RGF++ R
Sbjct: 4 PMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFRLPGRP----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
A S + RGIVE+CC C L LE YC
Sbjct: 59 -------------------ASRVSRRSRGIVEECCFRSCDLALLETYC 87
>gi|2135956|pir||I67610 insulin-like growth factor II, domains A-E - human
gi|182528|gb|AAA52443.1| (M17863) preproinsulin-like growth factor II, domains A-E [Homo
sapiens]
Length = 183
Score = 103 bits (257), Expect = 3e-22
Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 24/108 (22%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VCG+RGF+++
Sbjct: 4 PMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFS---------- 53
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q A S + RGIVE+CC C L LE YC
Sbjct: 54 --------------DFQRPASRVSRRSRGIVEECCFRSCDLALLETYC 87
>gi|33004|emb|CAA27249.1| (X03562) put. IGF-II [Homo sapiens]
Length = 180
Score = 103 bits (256), Expect = 4e-22
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 4 PMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 59 ----------------------VSRRSRGIVEECCFRSCDLALLETYC 84
>gi|4504609|ref|NP_000603.1| insulin-like growth factor 2 (somatomedin A); somatomedin A [Homo
sapiens]
gi|13640880|ref|XP_006402.3| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|14773150|ref|XP_028185.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|14773152|ref|XP_028188.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|14773154|ref|XP_028182.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|14773156|ref|XP_028189.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|14773158|ref|XP_028184.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|14773160|ref|XP_028187.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|14773162|ref|XP_028186.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
gi|124255|sp|P01344|IGF2_HUMAN INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II) (SOMATOMEDIN A)
gi|69363|pir||IGHU2 insulin-like growth factor II precursor - human
gi|32996|emb|CAA25426.1| (X00910) IGF-II precursor [Homo sapiens]
gi|33040|emb|CAA29516.1| (X06159) precursor polypeptide (AA -24 to 156) [Homo sapiens]
gi|182526|gb|AAA52442.1| (M17862) preproinsulin-like growth factor II, domains A-E [Homo
sapiens]
gi|183096|gb|AAA52535.1| (M14118) insulin-like growth factor [Homo sapiens]
gi|183124|gb|AAA52545.1| (J03242) insulin-like growth factor II precursor [Homo sapiens]
gi|189955|gb|AAA60088.1| (M17426) insulin-like growth factor II [Homo sapiens]
gi|914192|gb|AAB34155.1| (S77035) insulin-like growth factor II; IGF-II [Homo sapiens]
gi|10441885|gb|AAG17220.1|AF217977_1 (AF217977) unknown [Homo sapiens]
gi|12653519|gb|AAH00531.1|AAH00531 (BC000531) insulin-like growth factor 2 (somatomedin A) [Homo
sapiens]
gi|224070|prf||1009249A insulin-like growth factor II precursor [Homo sapiens]
gi|224885|prf||1203258B insulin-like growth factor II [Homo sapiens]
Length = 180
Score = 102 bits (255), Expect = 5e-22
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 4 PMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 59 ----------------------VSRRSRGIVEECCFRSCDLALLETYC 84
>gi|124657|sp|P04667|INS_ONCKE INSULIN PRECURSOR
gi|69342|pir||IPON insulin I precursor - chum salmon
gi|295725|emb|CAA31910.1| (X13559) preproinsulin [Oncorhynchus keta]
Length = 105
Score = 102 bits (255), Expect = 5e-22
Identities = 49/110 (44%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MA W L L+ L A QHLCGSHLV+ALYLVCGE+GFFYTPK R+ +
Sbjct: 1 MAFW--LQAASLLVLLALSPGVDAAAAQHLCGSHLVDALYLVCGEKGFFYTPK--RDVDP 56
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
L E + KRGIVEQCC C+++ L+NYCN
Sbjct: 57 LIGFLSPKSAKENEEYPFKDQTEM-MVKRGIVEQCCHKPCNIFDLQNYCN 105
>gi|1708500|sp|P01318|INS_SHEEP INSULIN PRECURSOR
gi|405982|gb|AAB60625.1| (U00668) insulin [Ovis aries]
Length = 105
Score = 102 bits (255), Expect = 6e-22
Identities = 85/110 (77%), Positives = 89/110 (80%), Gaps = 5/110 (4%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW RL+PLLALLALW P PA AFVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E
Sbjct: 1 MALWTRLVPLLALLALWAPAPAHAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEG 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QVG +EL GGPGAG L+ QKRGIVEQCC +CSLYQLENYCN
Sbjct: 61 PQVGALELAGGPGAGGLEGPP-----QKRGIVEQCCAGVCSLYQLENYCN 105
>gi|124650|sp|P01342|INS_MYXGL INSULIN PRECURSOR
gi|69353|pir||IPHF insulin precursor - Atlantic hagfish
gi|64093|emb|CAA23993.1| (V00649) reading frame preproinsulin [Myxine glutinosa]
Length = 115
Score = 102 bits (254), Expect = 8e-22
Identities = 47/116 (40%), Positives = 57/116 (48%), Gaps = 7/116 (6%)
Query: 1 MAL---WMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRRE 57
MAL ++PL+ LL+ P A HLCG LV ALY+ CG RGFFY P +
Sbjct: 1 MALSPFLAAVIPLVLLLSRA-PPSADTRTTGHLCGKDLVNALYIACGVRGFFYDPTKMKR 59
Query: 58 AEDLQVGQVELGGGPGAGSLQPLAL---EGSLQKRGIVEQCCTSICSLYQLENYCN 110
+ L S ++ E KRGIVEQCC CS+Y LENYCN
Sbjct: 60 DTGALAAFLPLAYAEDNESQDDESIGINEVLKSKRGIVEQCCHKRCSIYDLENYCN 115
>gi|33044|emb|CAA29517.1| (X06160) precursor polypeptide (AA -24 to 140) [Homo sapiens]
Length = 164
Score = 101 bits (252), Expect = 1e-21
Identities = 35/108 (32%), Positives = 45/108 (41%), Gaps = 24/108 (22%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VCG+RGF++ R
Sbjct: 4 PMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFRLPGRP----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
A S + RGIVE+CC C L LE YC
Sbjct: 59 -------------------ASRVSRRSRGIVEECCFRSCDLALLETYC 87
>gi|64362|emb|CAA24983.1| (X00148) preproinsulin [Oncorhynchus keta]
Length = 105
Score = 101 bits (251), Expect = 1e-21
Identities = 49/110 (44%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW L L+ L A QHLCG HLV+ALYLVCGE+GFFYTPK R+ +
Sbjct: 1 MALW--LQAASLLVLLALSPGVDAAAAQHLCGLHLVDALYLVCGEKGFFYTPK--RDVDP 56
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
L E + KRGIVEQCC C+++ L+NYCN
Sbjct: 57 LIGFLSPKSAKENEEYPFKDQTEM-MVKRGIVEQCCHRPCNIFDLQNYCN 105
>gi|12643999|sp|P13190|INS_CALMI INSULIN PRECURSOR
Length = 89
Score = 100 bits (250), Expect = 2e-21
Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ---VELGGGPGAGSLQPLAL 82
Q LCGSHLV+ALY VCGERGFFY+PK R+ L + L L
Sbjct: 2 PTQRLCGSHLVDALYFVCGERGFFYSPKQIRDVGPLSAFRDLEPPLDTEMEDRFPYRQQL 61
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYCN 110
GS KRGIVEQCC + CSL LE YCN
Sbjct: 62 AGSKMKRGIVEQCCHNTCSLVNLEGYCN 89
>gi|124564|sp|P01317|INS_BOVIN INSULIN PRECURSOR
gi|1070561|pir||IPBO insulin precursor - bovine
gi|163579|gb|AAA30722.1| (M54979) preproinsulin [Bos taurus]
Length = 105
Score = 100 bits (249), Expect = 3e-21
Identities = 86/110 (78%), Positives = 89/110 (80%), Gaps = 5/110 (4%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW RL PLLALLALW P PA AFVNQHLCGSHLVEALYLVCGERGFFYTPK RRE E
Sbjct: 1 MALWTRLRPLLALLALWPPPPARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEG 60
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
QVG +EL GGPGAG L+ QKRGIVEQCC S+CSLYQLENYCN
Sbjct: 61 PQVGALELAGGPGAGGLEGPP-----QKRGIVEQCCASVCSLYQLENYCN 105
>gi|124616|sp|P01310|INS_HORSE INSULIN PRECURSOR
gi|69301|pir||IPHO insulin precursor - horse
Length = 86
Score = 100 bits (248), Expect = 4e-21
Identities = 73/86 (84%), Positives = 74/86 (85%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK EAED QVG+VELGGGPG G LQPLAL G
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKAXXEAEDPQVGEVELGGGPGLGGLQPLALAG 60
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
Q GIVEQCCT ICSLYQLENYCN
Sbjct: 61 PQQXXGIVEQCCTGICSLYQLENYCN 86
>gi|56710|emb|CAA25427.1| (X00911) pot. MSA-precursor [Rattus norvegicus]
gi|224071|prf||1009250A protein,multiplication stimulating act [Rattus norvegicus]
Length = 191
Score = 99.2 bits (246), Expect = 6e-21
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VC +RGF+++ + R
Sbjct: 15 PVGKSMLVLLISLAFALCCIAAYRPSETLCGGELVDTLQFVCSDRGFYFSRPSSRAN--- 71
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ RGIVE+CC C L LE YC
Sbjct: 72 ------------------------RRSRGIVEECCFRSCDLALLETYC 95
>gi|69306|pir||IPPG insulin precursor - pig
Length = 84
Score = 98.9 bits (245), Expect = 8e-21
Identities = 72/86 (83%), Positives = 73/86 (84%), Gaps = 2/86 (2%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK RREAE+ Q G VE G G G LQ LALEG
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVE--LGGGLGGLQALALEG 58
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
QKRGIVEQCCTSICSLYQLENYCN
Sbjct: 59 PPQKRGIVEQCCTSICSLYQLENYCN 84
>gi|13937375|ref|NP_113699.1| insulin-like growth factor II (somatomedin A) [Rattus norvegicus]
gi|124258|sp|P01346|IGF2_RAT INSULIN-LIKE GROWTH FACTOR II PRECURSOR (MULTIPLICATION STIMULATING
POLYPEPTIDE) (IGF-II) (MULTIPLICATION STIMULATING
ACTIVITY) (MSA)
gi|69365|pir||IGRT2 insulin-like growth factor II precursor - rat
gi|56413|emb|CAA31493.1| (X13101) pre-IGFII [Rattus norvegicus]
gi|56417|emb|CAA32942.1| (X14833) pre-IGFII [Rattus norvegicus]
gi|56421|emb|CAA32943.1| (X14834) pre-IGFII [Rattus norvegicus]
gi|56429|emb|CAA26136.1| (X02213) IGF II precursor [Rattus norvegicus]
gi|56711|emb|CAA25428.1| (X00911) put. MSA-precursor [Rattus norvegicus]
gi|204773|gb|AAA41391.1| (M29880) insulin-like growth factor II [Rattus norvegicus]
gi|2769668|gb|AAB95624.1| (M13871) insulin-like growth factor II [Rattus norvegicus]
Length = 180
Score = 98.9 bits (245), Expect = 8e-21
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VC +RGF+++ + R
Sbjct: 4 PVGKSMLVLLISLAFALCCIAAYRPSETLCGGELVDTLQFVCSDRGFYFSRPSSRAN--- 60
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ RGIVE+CC C L LE YC
Sbjct: 61 ------------------------RRSRGIVEECCFRSCDLALLETYC 84
>gi|13517217|gb|AAK28708.1| (AF199584) preproinsulin [Ambloplites rupestris]
Length = 91
Score = 98.5 bits (244), Expect = 9e-21
Identities = 41/92 (44%), Positives = 49/92 (52%), Gaps = 9/92 (9%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGS-------LQ 78
QHLCGSHLV+ALYLVCG+RGFFY PK R+ + L G A
Sbjct: 2 PPQHLCGSHLVDALYLVCGDRGFFYNPK--RDVDPLMGFLPPKADGAAAPGGENEVAEFA 59
Query: 79 PLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
+ KRGIVEQCC C+++ L YCN
Sbjct: 60 FKDQMEMMVKRGIVEQCCHHPCNIFDLGRYCN 91
>gi|14773148|ref|XP_028183.1| insulin-like growth factor 2 (somatomedin A) [Homo sapiens]
Length = 135
Score = 98.1 bits (243), Expect = 1e-20
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 37 PMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 91
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 92 ----------------------VSRRSRGIVEECCFRSCDLALLETYC 117
>gi|3041701|sp|P51459|IGF2_HORSE INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II) (SOMATOMEDIN A)
gi|2558857|gb|AAC48807.1| (AF020599) insulin-like growth factor 2 [Equus caballus]
Length = 181
Score = 97.7 bits (242), Expect = 2e-20
Identities = 33/108 (30%), Positives = 44/108 (40%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ LL L LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 4 PVGKSLLMLFTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 59 ----------------------INRRSRGIVEECCFRSCDLALLETYC 84
>gi|1289271|emb|CAA65862.1| (X97225) insulin-like growth factor II [Oncorhynchus keta]
Length = 214
Score = 96.9 bits (240), Expect = 3e-20
Identities = 35/109 (32%), Positives = 48/109 (43%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ R+L + L L+ + A+A + LCG LV+AL VC +RGF+++ T R
Sbjct: 29 MSSSNRVLVIALALTLYIVEVASA---ETLCGGELVDALQFVCEDRGFYFSRPTSRSNSR 85
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+CC C L LE YC
Sbjct: 86 RS------------------------QNRGIVEECCFRSCDLNLLEQYC 110
>gi|729826|sp|Q08279|IGF2_CAVPO INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II) (SOMATOMEDIN A)
gi|2144129|pir||I57671 insulin-like growth factor II - guinea pig
gi|300071|gb|AAB26479.1| (S59899) insulin-like growth factor II; IGF-II [Cavia porcellus]
gi|383943|prf||1904317A insulin-like growth factor II [Cavia porcellus]
Length = 128
Score = 96.9 bits (240), Expect = 3e-20
Identities = 34/108 (31%), Positives = 46/108 (42%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
++ +L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 4 SMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 59 ----------------------VSRRSRGIVEECCFRSCDLALLETYC 84
>gi|6754310|ref|NP_034644.1| insulin-like growth factor 2 [Mus musculus]
gi|124256|sp|P09535|IGF2_MOUSE INSULIN-LIKE GROWTH FACTOR II PRECURSOR (MULTIPLICATION STIMULATING
POLYPEPTIDE) (IGF-II)
gi|90969|pir||A24913 insulin-like growth factor II precursor - mouse
gi|194502|gb|AAA37926.1| (M36332) insulin-like growth factor II precursor [Mus musculus]
gi|309250|gb|AAA37683.1| (M14951) preproinsulin-like growth factor II [Mus musculus]
gi|1753231|gb|AAC53516.1| (U71085) insulin-like growth factor II [Mus musculus]
Length = 180
Score = 96.9 bits (240), Expect = 3e-20
Identities = 32/108 (29%), Positives = 43/108 (39%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA + LCG LV+ L VC +RGF+++ + R
Sbjct: 4 PVGKSMLVLLISLAFALCCIAAYGPGETLCGGELVDTLQFVCSDRGFYFSRPSSRAN--- 60
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ RGIVE+CC C L LE YC
Sbjct: 61 ------------------------RRSRGIVEECCFRSCDLALLETYC 84
>gi|729827|sp|Q02816|IGF2_ONCMY INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II) (ERYTHROTROPIN)
gi|422578|pir||B46244 insulin-like growth factor II precursor - rainbow trout
gi|213434|gb|AAA49411.1| (M95184) insulin-like growth factor II [Oncorhynchus mykiss]
Length = 214
Score = 96.5 bits (239), Expect = 3e-20
Identities = 35/109 (32%), Positives = 48/109 (43%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ R+L + L L+ + A+A + LCG LV+AL VC +RGF+++ T R
Sbjct: 29 MSSSNRVLVIALALTLYIVEVASA---ETLCGGELVDALQFVCEDRGFYFSRPTSRSNSR 85
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+CC C L LE YC
Sbjct: 86 RS------------------------QNRGIVEECCFRSCDLNLLEQYC 110
>gi|33048|emb|CAA29518.1| (X06161) precursor polypeptide (AA -24 t0 82) (423 is 1st base in
codon) [Homo sapiens]
Length = 105
Score = 96.5 bits (239), Expect = 4e-20
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ +L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 4 PMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 59 ----------------------VSRRSRGIVEECCFRSCDLALLETYC 84
>gi|124547|sp|P01333|INS_ANAPL INSULIN PRECURSOR
gi|69328|pir||IPDK insulin precursor - duck (tentative sequence)
Length = 81
Score = 95.4 bits (236), Expect = 8e-20
Identities = 50/85 (58%), Positives = 53/85 (61%), Gaps = 5/85 (5%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
NQHLCGSHLVEALYLVCGERGFFY+PKT + E V G P
Sbjct: 2 ANQHLCGSHLVEALYLVCGERGFFYSPKTXXDVEQPLVNGPLH----GEVGELPFQ-HEE 56
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
Q GIVEQCC + CSLYQLENYCN
Sbjct: 57 YQXXGIVEQCCENPCSLYQLENYCN 81
>gi|56713|emb|CAA25429.1| (X00911) pot. MSA-precursor [Rattus norvegicus]
Length = 172
Score = 94.6 bits (234), Expect = 1e-19
Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 27/103 (26%)
Query: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66
+L LL LA AA ++ LCG LV+ L VC +RGF+++ + R
Sbjct: 1 MLVLLISLAFALCCIAAYRPSETLCGGELVDTLQFVCSDRGFYFSRPSSRAN-------- 52
Query: 67 ELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ RGIVE+CC C L LE YC
Sbjct: 53 -------------------RRSRGIVEECCFRSCDLALLETYC 76
>gi|124365|sp|P22334|ILP_BRACL INSULIN-LIKE PEPTIDE PRECURSOR
gi|103686|pir||A38422 insulin-like protein precursor - California lancelet
gi|156051|gb|AAA62720.1| (M55302) insulin-like peptide [Branchiostoma californiense]
Length = 305
Score = 94.6 bits (234), Expect = 1e-19
Identities = 34/107 (31%), Positives = 56/107 (51%), Gaps = 16/107 (14%)
Query: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPK---TRREAEDLQV 63
+L LA++ L + A ++LCGS L + L VCG RG+ P+ ++R + +
Sbjct: 8 VLASLAVVCLLVKETQA----EYLCGSTLADVLSFVCGNRGYNSQPRRSVSKRAIDFISE 63
Query: 64 GQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
Q + G A+ ++RG+VE+CC ++C QLE+YCN
Sbjct: 64 QQAKDYMG---------AMPHIRRRRGLVEECCYNVCDYSQLESYCN 101
>gi|14758705|ref|XP_052653.1| insulin-like growth factor 1 (somatomedin C) [Homo sapiens]
gi|14758749|ref|XP_052648.1| insulin-like growth factor 1 (somatomedin C) [Homo sapiens]
gi|124263|sp|P05019|IGFB_HUMAN INSULIN-LIKE GROWTH FACTOR IB PRECURSOR (IGF-IB) (SOMATOMEDIN C)
gi|69361|pir||IGHU1B insulin-like growth factor I precursor, splice form B [validated] -
human
gi|32992|emb|CAA40093.1| (X56774) IGF-1b [Homo sapiens]
gi|183109|gb|AAA52537.1| (M14156) insulin-like growth factor IB [Homo sapiens]
gi|183112|gb|AAA52539.1| (M11568) insulin-like growth factor IB prepropeptide [Homo sapiens]
Length = 195
Score = 92.3 bits (228), Expect = 7e-19
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 32 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|14571867|gb|AAK67297.1|AF282621_1 (AF282621) IGFII-GFP fusion protein [synthetic construct]
Length = 512
Score = 91.9 bits (227), Expect = 8e-19
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ R L L L+ + A+A + LCG LV+AL VC +RGF+++ T R +
Sbjct: 82 MSSSSRALLFALALTLYVVEMASA---ETLCGGELVDALQFVCEDRGFYFSRPTSRGSNR 138
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+CC C L LE YC
Sbjct: 139 RP------------------------QNRGIVEECCFRSCDLNLLEQYC 163
>gi|12644472|sp|Q95222|IGF1_RABIT INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|2522202|gb|AAB80950.1| (AF022961) insulin-like growth factor IB [Oryctolagus cuniculus]
Length = 143
Score = 91.5 bits (226), Expect = 1e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 16 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 72
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 73 ---------------------TGIVDECCFRSCDLRRLEMYC 93
>gi|12231523|gb|AAG49142.1|AF225573_1 (AF225573) SooQI-507GFP fusion protein [synthetic construct]
gi|14150459|gb|AAK54503.1|AF267910_1 (AF267910) 48 kDa IGF-II fusion protein [synthetic construct]
Length = 459
Score = 91.5 bits (226), Expect = 1e-18
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ R L L L+ + A+A + LCG LV+AL VC +RGF+++ T R +
Sbjct: 29 MSSSSRALLFALALTLYVVEMASA---ETLCGGELVDALQFVCEDRGFYFSRPTSRGSNR 85
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+CC C L LE YC
Sbjct: 86 RP------------------------QNRGIVEECCFRSCDLNLLEQYC 110
>gi|124265|sp|P08024|IGFB_RAT INSULIN-LIKE GROWTH FACTOR IB PRECURSOR (IGF-IB) (SOMATOMEDIN)
gi|111860|pir||A27804 insulin-like growth factor I precursor - rat
gi|204299|gb|AAA41214.1| (M15651) insulin-like growth factor [Rattus norvegicus]
Length = 181
Score = 91.5 bits (226), Expect = 1e-18
Identities = 33/102 (32%), Positives = 43/102 (41%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 32 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|124253|sp|P16501|IGF1_XENLA INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|104165|pir||A36079 insulin-like growth factor I'' precursor - African clawed frog
gi|214288|gb|AAA70330.1| (M29857) insulin-like growth factor [Xenopus laevis]
Length = 153
Score = 91.1 bits (225), Expect = 1e-18
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 24/106 (22%)
Query: 5 MRLLPLL-ALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQV 63
M + LL +L +AA + LCG+ LV+ L VCG+RGF+++ T + +
Sbjct: 27 MSCIHLLYLVLCFLTLTHSAAAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGSNNR-- 84
Query: 64 GQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C +LE YC
Sbjct: 85 ---------------------RSHHRGIVDECCFQSCDFRRLEMYC 109
>gi|1100903|gb|AAA96152.1| (U40870) insulin-like growth factor-I [Homo sapiens]
Length = 139
Score = 91.1 bits (225), Expect = 2e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 13 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 69
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 70 ---------------------TGIVDECCFRSCDLRRLEMYC 90
>gi|108319|pir||A34938 insulin-like growth factor IA precursor - pig (fragment)
Length = 134
Score = 90.8 bits (224), Expect = 2e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 13 LFYLALCLLSFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 69
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 70 ---------------------TGIVDECCFRSCDLRRLEMYC 90
>gi|1850346|gb|AAB48032.1| (U75390) insulin-like growth factor 1 precursor [Oryctolagus
cuniculus]
Length = 137
Score = 90.8 bits (224), Expect = 2e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 16 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 72
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 73 ---------------------TGIVDECCFRSCDLRRLEMYC 93
>gi|14758736|ref|XP_052652.1| insulin-like growth factor 1 (somatomedin C) [Homo sapiens]
gi|106739|pir||A36552 insulin-like growth factor 1a precursor - human
gi|184834|gb|AAA52789.1| (M37484) insulin-like growth factor I [Homo sapiens]
Length = 137
Score = 90.4 bits (223), Expect = 2e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 16 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 72
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 73 ---------------------TGIVDECCFRSCDLRRLEMYC 93
>gi|109037|pir||S22878 insulin-like growth factor I precursor, splice form 2 - sheep
gi|1839018|emb|CAA35098.1| (X17229) insuline-like growth factor-I (2) [Ovis aries]
Length = 138
Score = 90.4 bits (223), Expect = 3e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 17 LFYLALCLLAFTTSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 73
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 74 ---------------------TGIVDECCFRSCDLRRLEMYC 94
>gi|109035|pir||B33390 insulin-like growth factor I precursor (clone A21) - sheep
gi|165933|gb|AAA80534.1| (M31734) insulin-like growth factor I [Ovis aries]
gi|833787|emb|CAA49231.1| (X69472) insulin like growth factor-I [Ovis aries]
Length = 138
Score = 90.4 bits (223), Expect = 3e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 17 LFYLALCLLAFSSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 73
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 74 ---------------------TGIVDECCFRSCDLRRLEMYC 94
>gi|8100793|gb|AAF72409.1| (AF210387) insulin-like growth factor I [Bos taurus]
Length = 133
Score = 90.4 bits (223), Expect = 3e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 12 LFYLALCLLAFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 68
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 69 ---------------------TGIVDECCFRSCDLRRLEMYC 89
>gi|69362|pir||IGGP1 insulin-like growth factor I precursor - guinea pig
Length = 137
Score = 90.0 bits (222), Expect = 3e-18
Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 24/108 (22%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
A+ L LA L A A + LCG+ LV+AL VCG+RGF++ T +
Sbjct: 10 AVSSSHLFYLAFCLLVLTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSR 68
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ Q GIV++CC C L +LE YC
Sbjct: 69 RAPQ-----------------------TGIVDECCFRSCDLRRLEMYC 93
>gi|124262|sp|P08025|IGFA_RAT INSULIN-LIKE GROWTH FACTOR IA PRECURSOR (IGF-IA) (SOMATOMEDIN)
gi|111865|pir||B27804 insulin-like growth factor IA precursor - rat
gi|204300|gb|AAA41215.1| (M15651) insulin-like growth factor [Rattus norvegicus]
Length = 153
Score = 90.0 bits (222), Expect = 3e-18
Identities = 33/102 (32%), Positives = 43/102 (41%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 32 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|164474|gb|AAA31043.1| (M31175) insulin-like growth factor I precursor [Sus scrofa]
Length = 130
Score = 90.0 bits (222), Expect = 3e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 9 LFYLALCLLSFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 65
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 66 ---------------------TGIVDECCFRSCDLRRLEMYC 86
>gi|124248|sp|P17647|IGF1_CAVPO INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|49548|emb|CAA37127.1| (X52951) precursor protein (AA -25 to 105) [Cavia porcellus]
Length = 130
Score = 90.0 bits (222), Expect = 4e-18
Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 24/108 (22%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
A+ L LA L A A + LCG+ LV+AL VCG+RGF++ T +
Sbjct: 3 AVSSSHLFYLAFCLLVLTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSR 61
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ Q GIV++CC C L +LE YC
Sbjct: 62 RAPQ-----------------------TGIVDECCFRSCDLRRLEMYC 86
>gi|462403|sp|P33712|IGF1_CANFA INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|484995|pir||PN0622 insulin-like growth factor Ia precursor - dog (fragment)
Length = 122
Score = 90.0 bits (222), Expect = 4e-18
Identities = 35/102 (34%), Positives = 46/102 (44%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L P PA A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 3 LFYLALCLLTFPSPATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 59
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 60 ---------------------TGIVDECCFRSCDLRRLEMYC 80
>gi|6754308|ref|NP_034642.1| insulin-like growth factor 1 [Mus musculus]
gi|124264|sp|P05018|IGFB_MOUSE INSULIN-LIKE GROWTH FACTOR IB PRECURSOR (IGF-IB) (SOMATOMEDIN)
gi|51807|emb|CAA28170.1| (X04482) prepro IGF-IB (aa -22 to 111) [Mus musculus]
gi|15214569|gb|AAH12409.1|AAH12409 (BC012409) Similar to insulin-like growth factor 1 [Mus musculus]
Length = 133
Score = 89.6 bits (221), Expect = 4e-18
Identities = 32/102 (31%), Positives = 42/102 (40%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 6 LFYLALCLLTFTSSTTAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 62
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 63 ---------------------TGIVDECCFRSCDLRRLEMYC 83
>gi|3309072|gb|AAC26006.1| (AF074980) insulin-like growth factor-I precursor [Meleagris
gallopavo]
Length = 153
Score = 89.6 bits (221), Expect = 5e-18
Identities = 33/102 (32%), Positives = 45/102 (43%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
LAL L AAA + LCG+ LV+AL VCG+RGF+++ T +
Sbjct: 32 FFYLALCLLTLTSSAAAGP-ETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSR------ 84
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
L +GIV++CC C L +LE YC
Sbjct: 85 -----------------RLHHKGIVDECCFQSCDLRRLEMYC 109
>gi|92423|pir||A26859 insulin-like growth factor IB precursor - rat
gi|56425|emb|CAA29480.1| (X06107) IGF-I (AA 1-159) [Rattus norvegicus]
gi|56427|emb|CAA29481.1| (X06108) IGF-I (AA 1-159) [Rattus norvegicus]
Length = 159
Score = 89.2 bits (220), Expect = 5e-18
Identities = 33/102 (32%), Positives = 43/102 (41%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 32 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|165931|gb|AAA80533.1| (M30653) insulin-like growth factor I [Ovis aries]
gi|165934|gb|AAA80535.1| (M31734) insulin-like growth factor I [Ovis aries]
gi|165936|gb|AAA31545.1| (M31736) insulin-like growth factor I precursor [Ovis aries]
gi|165939|gb|AAA31547.1| (M31735) insulin-like growth factor I precursor A' [Ovis aries]
gi|833788|emb|CAA49232.1| (X69473) insulin like growth factor-I [Ovis aries]
Length = 130
Score = 89.2 bits (220), Expect = 6e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 9 LFYLALCLLAFSSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 65
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 66 ---------------------TGIVDECCFRSCDLRRLEMYC 86
>gi|183120|gb|AAA52543.1| (M29644) insulin-like growth factor I precursor [Homo sapiens]
gi|224884|prf||1203258A insulin-like growth factor I [Homo sapiens]
Length = 130
Score = 89.2 bits (220), Expect = 6e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 9 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 65
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 66 ---------------------TGIVDECCFRSCDLRRLEMYC 86
>gi|14571865|gb|AAK67296.1|AF282620_1 (AF282620) SIGF1-GFP fusion protein [synthetic construct]
Length = 526
Score = 88.8 bits (219), Expect = 7e-18
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 146 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPN----------- 194
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 195 --------------ARRSRGIVDECCFQSCELRRLEMYC 219
>gi|204752|gb|AAA41386.1| (M17335) insulin like growth factor I [Rattus norvegicus]
gi|220781|dbj|BAA00604.1| (D00698) insulin-like growth factor I precursor [Rattus sp.]
Length = 127
Score = 88.8 bits (219), Expect = 7e-18
Identities = 33/102 (32%), Positives = 43/102 (41%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 6 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 62
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 63 ---------------------TGIVDECCFRSCDLRRLEMYC 83
>gi|1815685|gb|AAB47485.1| (U85272) prepro IGF-Ia [Equus caballus]
Length = 127
Score = 88.8 bits (219), Expect = 8e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 6 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 62
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 63 ---------------------TGIVDECCFRSCDLRRLEMYC 83
>gi|124251|sp|P16545|IGF1_PIG INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|108318|pir||S12825 insulin-like growth factor I precursor - pig
Length = 153
Score = 88.8 bits (219), Expect = 9e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 32 LFYLALCLLSFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|1708431|sp|P51462|IGF1_COTJA INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
Length = 124
Score = 88.5 bits (218), Expect = 9e-18
Identities = 32/102 (31%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L L L AAA + LCG+ LV+AL VCG+RGF+++ T +
Sbjct: 3 FFYLGLCLLTLTSSAAAGP-ETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSR------ 55
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
L +GIV++CC C L +LE YC
Sbjct: 56 -----------------RLHHKGIVDECCFQSCDLRRLEMYC 80
>gi|1070562|pir||IGBO1 insulin-like growth factor IA precursor - bovine (fragment)
gi|455|emb|CAA33746.1| (X15726) prepro-insulin-like growth factor I [Bos taurus]
Length = 153
Score = 88.5 bits (218), Expect = 9e-18
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 32 LFYLALCLLAFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|14279401|gb|AAK58584.1|AF268051_1 (AF268051) insulin-like growth factor 1 precursor; somatomedin
precursor [Danio rerio]
gi|14279476|gb|AAK58609.1| (AF270704) insulin-like growth factor IL precursor; somatomedin
precursor [Danio rerio]
Length = 161
Score = 88.5 bits (218), Expect = 1e-17
Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 28/110 (25%)
Query: 5 MRLLP-----LLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
MR LP L L L + LCG+ LV+ L VCG+RGF+++ T
Sbjct: 19 MRCLPSTHTLSLVLCVLALTPATLEAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGPS 78
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 79 SR-----------------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|124261|sp|P05017|IGFA_MOUSE INSULIN-LIKE GROWTH FACTOR IA PRECURSOR (IGF-IA) (SOMATOMEDIN)
gi|90967|pir||A25540 insulin-like growth factor IA precursor - mouse
gi|51802|emb|CAA28168.1| (X04480) put. preproIGF-IA (AA -22 to 105) [Mus musculus]
Length = 127
Score = 88.5 bits (218), Expect = 1e-17
Identities = 32/102 (31%), Positives = 42/102 (40%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 6 LFYLALCLLTFTSSTTAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 62
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 63 ---------------------TGIVDECCFRSCDLRRLEMYC 83
>gi|124247|sp|P07455|IGF1_BOVIN INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
Length = 154
Score = 88.5 bits (218), Expect = 1e-17
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 33 LFYLALCLLAFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 89
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 90 ---------------------TGIVDECCFRSCDLRRLEMYC 110
>gi|13936438|gb|AAK49814.1|AF246977_1 (AF246977) 45 kDa IGFI-GFP fusion protein [synthetic construct]
gi|14150457|gb|AAK54502.1|AF267909_1 (AF267909) 45 kDa SIGFI-GFP fusion protein [synthetic construct]
Length = 410
Score = 88.5 bits (218), Expect = 1e-17
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPN----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELRRLEMYC 103
>gi|1083101|pir||JC2483 insulin-like growth factor-I precursor - goat
gi|217667|dbj|BAA01976.1| (D11378) prepro IGF-I [Capra hircus]
gi|1094408|prf||2106155A insulin-like growth factor I [Capra hircus]
Length = 154
Score = 88.5 bits (218), Expect = 1e-17
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 33 LFYLALCLLAFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 89
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 90 ---------------------TGIVDECCFRSCDLRRLEMYC 110
>gi|2118612|pir||A33390 insulin-like growth factor I precursor, splice form 1 - sheep
Length = 154
Score = 88.1 bits (217), Expect = 1e-17
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 33 LFYLALCLLAFTTSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 89
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 90 ---------------------TGIVDECCFRSCDLRRLEMYC 110
>gi|124252|sp|P10763|IGF1_SHEEP INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|165930|gb|AAA80532.1| (M30653) insulin-like growth factor I [Ovis aries]
gi|165938|gb|AAA31546.1| (M31735) insulin-like growth factor I precursor A [Ovis aries]
gi|833786|emb|CAA49230.1| (X69472) insulin like growth factor-I [Ovis aries]
Length = 154
Score = 88.1 bits (217), Expect = 1e-17
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 33 LFYLALCLLAFSSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 89
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 90 ---------------------TGIVDECCFRSCDLRRLEMYC 110
>gi|223828|prf||1001199A insulin-like growth factor I precursor [Homo sapiens]
Length = 156
Score = 88.1 bits (217), Expect = 1e-17
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 35 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 91
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 92 ---------------------TGIVDECCFRSCDLRRLEMYC 112
>gi|11024682|ref|NP_000609.1| insulin-like growth factor 1 (somatomedia C); insulin-like growth
factor 1 (somatomedin C) [Homo sapiens]
gi|14758696|ref|XP_052654.1| insulin-like growth factor 1 (somatomedin C) [Homo sapiens]
gi|14758713|ref|XP_052647.1| insulin-like growth factor 1 (somatomedin C) [Homo sapiens]
gi|14758722|ref|XP_052649.1| insulin-like growth factor 1 (somatomedin C) [Homo sapiens]
gi|14758734|ref|XP_052651.1| insulin-like growth factor 1 (somatomedin C) [Homo sapiens]
gi|124260|sp|P01343|IGFA_HUMAN INSULIN-LIKE GROWTH FACTOR IA PRECURSOR (IGF-IA) (SOMATOMEDIN C)
gi|69359|pir||IGHU1 insulin-like growth factor I precursor, splice form A [validated] -
human
gi|32990|emb|CAA40092.1| (X56773) IGF-1a [Homo sapiens]
gi|33008|emb|CAA40342.1| (X57025) insulin-like growth factor I [Homo sapiens]
gi|33016|emb|CAA24998.1| (X00173) insulin-like growth factor 1A precursor [Homo sapiens]
gi|183110|gb|AAA52538.1| (M14156) insulin-like growth factor precursor IA [Homo sapiens]
gi|306927|gb|AAA52787.1| (M27544) insulin-like growth factor precursor [Homo sapiens]
Length = 153
Score = 88.1 bits (217), Expect = 1e-17
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 32 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|111863|pir||B40912 insulin-like growth factor I precursor form 2 - rat
gi|204754|gb|AAA41387.1| (M15481) insulin-like growth factor precursor [Rattus norvegicus]
Length = 127
Score = 87.7 bits (216), Expect = 2e-17
Identities = 33/102 (32%), Positives = 43/102 (41%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 6 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 62
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 63 ---------------------TGIVDECCFRSCDLRRLEMYC 83
>gi|124249|sp|P18254|IGF1_CHICK INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|104738|pir||A41399 insulin-like growth factor IA precursor - chicken
gi|211951|gb|AAA48828.1| (M32791) insulin-like growth factor precursor [Gallus gallus]
gi|7416840|dbj|BAA94079.1| (AB035804) IGF-I [Struthio camelus]
Length = 153
Score = 87.7 bits (216), Expect = 2e-17
Identities = 32/102 (31%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L L L AAA + LCG+ LV+AL VCG+RGF+++ T +
Sbjct: 32 FFYLGLCLLTLTSSAAAGP-ETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSR------ 84
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
L +GIV++CC C L +LE YC
Sbjct: 85 -----------------RLHHKGIVDECCFQSCDLRRLEMYC 109
>gi|7677623|gb|AAF67202.1|AF260131_1 (AF260131) IGF-I [Coturnix japonica]
Length = 153
Score = 87.3 bits (215), Expect = 2e-17
Identities = 32/102 (31%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L L L AAA + LCG+ LV+AL VCG+RGF+++ T +
Sbjct: 32 FFYLGLCLLTLTSSAAAGP-ETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSR------ 84
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
L +GIV++CC C L +LE YC
Sbjct: 85 -----------------RLHHKGIVDECCFQSCDLRRLEMYC 109
>gi|13249283|gb|AAK16727.1|AF332865_1 (AF332865) insulin-like growth factor I [Megalobrama amblycephala]
Length = 161
Score = 87.3 bits (215), Expect = 2e-17
Identities = 29/104 (27%), Positives = 41/104 (38%), Gaps = 24/104 (23%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
L L+ + P A + LCG+ LV+ L VCG+RGF+++ T
Sbjct: 26 HTLSLVLFVLALTPATLEAGP-ETLCGAELVDTLQFVCGDRGFYFSKPTGYGPSSR---- 80
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 -------------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|63530|emb|CAA23707.1| (V00416) part of reading frame [Gallus gallus]
Length = 62
Score = 86.9 bits (214), Expect = 3e-17
Identities = 44/62 (70%), Positives = 48/62 (76%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW+R LPLLALL GP + A NQHLCGSHLVEALYLVCGERGFFY+PK RR+ E
Sbjct: 1 MALWIRSLPLLALLVFSGPGTSYAAANQHLCGSHLVEALYLVCGERGFFYSPKARRDVEQ 60
Query: 61 LQ 62
Sbjct: 61 PL 62
>gi|1708430|sp|P51457|IGF1_CAPHI INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
Length = 154
Score = 86.9 bits (214), Expect = 3e-17
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 33 LFYLALCLLAFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFXKPTGYGSSSRRAPQ-- 89
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 90 ---------------------TGIVDECCFRSCDLRRLEMYC 110
>gi|111862|pir||A40912 insulin-like growth factor I precursor form 1 - rat
gi|204750|gb|AAA41385.1| (M15480) insulin-like growth factor precursor [Rattus norvegicus]
Length = 133
Score = 86.9 bits (214), Expect = 3e-17
Identities = 33/102 (32%), Positives = 43/102 (41%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 6 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ-- 62
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 63 ---------------------TGIVDECCFRSCDLRRLEMYC 83
>gi|2497406|sp|Q90326|IGFB_CYPCA INSULIN-LIKE GROWTH FACTOR I, JUVENILE FORM PRECURSOR
gi|1434896|dbj|BAA11879.1| (D83272) insulin-like growth factor I [Cyprinus carpio]
Length = 161
Score = 86.9 bits (214), Expect = 3e-17
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 28/110 (25%)
Query: 5 MRLL-----PLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
MR L L L L + LCG+ LV+ L VCG+RGF+++ T
Sbjct: 19 MRCLSCTHTLSLVLCVLALTPATLEAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGPS 78
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 79 SR-----------------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|225446|prf||1303322A insulin [Oncorhynchus keta]
Length = 94
Score = 86.9 bits (214), Expect = 3e-17
Identities = 44/99 (44%), Positives = 50/99 (50%), Gaps = 5/99 (5%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
MALW L L+ L A QHLCGSHLV+ALYLVCGE+GFFYTPK R+ +
Sbjct: 1 MALW--LQAASLLVLLALSPGVDAAAAQHLCGSHLVDALYLVCGEKGFFYTPK--RDVDP 56
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSI 99
L E + KRGIVEQCC
Sbjct: 57 LIGFLSPKSAKENEEYPFKDQTEM-MVKRGIVEQCCHRP 94
>gi|9457240|gb|AAB37702.2| (S82374) insulin-like growth factor I subtype Ea2 [Cyprinus carpio]
Length = 178
Score = 86.9 bits (214), Expect = 3e-17
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 28/110 (25%)
Query: 5 MRLL-----PLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
MR L L L L + LCG+ LV+ L VCG+RGF+++ T
Sbjct: 36 MRCLSCTHTLSLVLCVLALTPATLEAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGPS 95
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 96 SR-----------------------RSHNRGIVDECCFQSCELRRLEMYC 122
>gi|124259|sp|P10764|IGF2_SHEEP INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II)
gi|89872|pir||S04858 insulin-like growth factor II precursor - sheep
gi|1263|emb|CAA37621.1| (X53554) precursor polypeptide (AA -24 to 155) [Ovis aries]
gi|1267|emb|CAA39163.1| (X55638) insulin-like growth factor-II prepropeptide [Ovis aries]
gi|1803|emb|CAA33324.1| (X15248) prepro-IGF-II (AA -24 to 155) [Ovis aries]
gi|165941|gb|AAA31548.1| (M89788) insulin-like growth factor II [Ovis aries]
gi|405983|gb|AAB60626.1| (U00668) insulin-like growth factor II [Ovis aries]
Length = 179
Score = 86.5 bits (213), Expect = 3e-17
Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 27/106 (25%)
Query: 4 WMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQV 63
+L LLA LA AA ++ LCG LV+ L VCG+RGF+++ + R
Sbjct: 6 GKSMLALLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSR------- 58
Query: 64 GQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 59 --------------------INRRSRGIVEECCFRSCDLALLETYC 84
>gi|2497405|sp|Q90325|IGFA_CYPCA INSULIN-LIKE GROWTH FACTOR I, ADULT FORM PRECURSOR
gi|1434894|dbj|BAA11878.1| (D83271) insulin-like growth factor I [Cyprinus carpio]
Length = 161
Score = 86.1 bits (212), Expect = 5e-17
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 28/110 (25%)
Query: 5 MRLL-----PLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
MR L L L L + LCG+ LV+ L VCG+RGF+++ T
Sbjct: 19 MRCLSCTHTLSLVLCVLALTPATLEAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGPS 78
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 79 SR-----------------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|3982555|gb|AAC83444.1| (AF001006) insulin-like growth factor-I [Carassius auratus]
Length = 161
Score = 86.1 bits (212), Expect = 5e-17
Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 28/110 (25%)
Query: 5 MRLL-----PLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
MR L L L L P + LCG+ LV+ L VCG+RGF+++ T
Sbjct: 19 MRCLSCTHTLSLVLCVLASTPPTLEAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGPS 78
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 79 SR-----------------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|345552|pir||B44012 proIGF-IA-2=insulin-like growth factor I prohormone (alternatively
spliced) - Oncorhynchus kisutch=coho salmon (fragment)
gi|213441|gb|AAB59948.1| (M81912) insulin-like growth factor I [Oncorhynchus kisutch]
Length = 143
Score = 86.1 bits (212), Expect = 5e-17
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 4 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 54
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 55 --------------RSHNRGIVDECCFQSCELRRLEMYC 79
>gi|1352443|sp|P23695|IGF2_PIG INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II)
gi|288524|emb|CAA39574.1| (X56094) insulin-like-growth factor 2 preproprotein [Sus scrofa]
Length = 181
Score = 85.8 bits (211), Expect = 6e-17
Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ LL LL LAL AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 4 PMRKPLLVLLVFLALASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 59 ----------------------VNRRSRGIVEECCFRSCDLALLETYC 84
>gi|124254|sp|P07456|IGF2_BOVIN INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II) (ERYTHROTROPIN)
gi|1070563|pir||IGBO2 insulin-like growth factor II precursor - bovine
Length = 155
Score = 85.8 bits (211), Expect = 7e-17
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 27/87 (31%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VCG+RGF+++ + R
Sbjct: 1 AYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSR-------------------------- 34
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 35 -INRRSRGIVEECCFRSCDLALLETYC 60
>gi|420123|pir||B60738 insulin-like growth factor II precursor - pig
Length = 181
Score = 85.4 bits (210), Expect = 8e-17
Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 27/108 (25%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ LL LL LAL AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 4 PMRKPLLVLLVPLALASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR----- 58
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 59 ----------------------VNRRSRGIVEECCFRSCDLALLETYC 84
>gi|3158363|gb|AAC17495.1| (AF033801) insulin-like growth factor II [Tilapia sp.]
Length = 215
Score = 85.4 bits (210), Expect = 9e-17
Identities = 35/109 (32%), Positives = 46/109 (42%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ R L L L+ + A+A + LCG LV+AL VC +RGF+++ T R
Sbjct: 29 MSSTSRALLFALALTLYVVEMASA---ETLCGGELVDALQFVCEDRGFYFSRPTSRGNNR 85
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+CC C L LE YC
Sbjct: 86 RP------------------------QTRGIVEECCFRSCDLNLLEQYC 110
>gi|1994|emb|CAA35527.1| (X17492) insulin like growth factor I (118 AA) [Sus scrofa]
Length = 118
Score = 85.0 bits (209), Expect = 1e-16
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 24/98 (24%)
Query: 12 ALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGG 71
AL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 1 ALCLLSFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ------ 53
Query: 72 PGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 54 -----------------TGIVDECCFRSCDLRRLEMYC 74
>gi|2282046|gb|AAB64195.1| (AF007943) insulin-like growth factor II [Lates calcarifer]
Length = 215
Score = 84.6 bits (208), Expect = 1e-16
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ R L L L+ + A+A + LCG LV+AL VC +RGF+++ T R +
Sbjct: 29 MSSSSRALLFALALTLYVVEMASA---ETLCGGELVDALQFVCEDRGFYFSRPTSRGSNR 85
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+CC C L LE YC
Sbjct: 86 RP------------------------QNRGIVEECCFRSCDLNLLEQYC 110
>gi|7546360|pdb|1EFE|A Chain A, An Active Mini-Proinsulin, M2pi
Length = 60
Score = 84.6 bits (208), Expect = 1e-16
Identities = 56/86 (65%), Positives = 57/86 (66%), Gaps = 26/86 (30%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRR D+
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRRYPGDV----------------------- 37
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
KRGIVEQCCTSICSLYQLENYCN
Sbjct: 38 ---KRGIVEQCCTSICSLYQLENYCN 60
>gi|1708432|sp|P51458|IGF1_HORSE INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|881509|gb|AAA68952.1| (U28070) insulin-like growth factor precursor [Equus caballus]
Length = 122
Score = 83.8 bits (206), Expect = 2e-16
Identities = 33/102 (32%), Positives = 44/102 (42%), Gaps = 24/102 (23%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L LAL L A A + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 32 LFYLALCLLTFTSSATAGP-ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-- 88
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 89 ---------------------TGIVDECCFRSCDLRRLEMYC 109
>gi|2118611|pir||S58036 insulin-like growth factor I, precursor - spiny dogfish
gi|2133792|pir||S66485 insulin-like growth factor I precursor - spiny dogfish
gi|902731|emb|CAA90412.1| (Z50081) insulin-like growth factor I [Squalus acanthias]
Length = 126
Score = 83.8 bits (206), Expect = 3e-16
Identities = 30/102 (29%), Positives = 38/102 (36%), Gaps = 26/102 (25%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L L L L A + LCG+ LV+AL VCG+RGF++ +
Sbjct: 9 LFYLTLCVLTLSGVEA--SPETLCGAELVDALQFVCGDRGFYFNKPAGYRSS-------- 58
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV +CC C L LE YC
Sbjct: 59 ----------------VRRPHRGIVNECCFQSCDLKLLEMYC 84
>gi|423313|pir||S32558 insulin-like growth factor II - sheep
gi|552424|gb|AAA31549.1| (M89789) insulin-like growth factor II [Ovis aries]
Length = 120
Score = 83.8 bits (206), Expect = 3e-16
Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 27/106 (25%)
Query: 4 WMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQV 63
+L LLA LA AA ++ LCG LV+ L VCG+RGF+++ + R
Sbjct: 6 GKSMLALLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSR------- 58
Query: 64 GQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 59 --------------------INRRSRGIVEECCFRSCDLALLETYC 84
>gi|345553|pir||C44012 insulin-like growth factor I precursor, splice form 3 - coho salmon
(fragment)
gi|213443|gb|AAA49413.1| (M81913) insulin-like growth factor I [Oncorhynchus kisutch]
Length = 155
Score = 83.4 bits (205), Expect = 3e-16
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 4 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 54
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 55 --------------RSHNRGIVDECCFQSCELRRLEMYC 79
>gi|738041|prf||1924192A insulin-like growth factor I [Oncorhynchus keta]
Length = 176
Score = 83.1 bits (204), Expect = 4e-16
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|7649259|gb|AAF65819.1| (AF247658) insulin-like growth factor-I [Ctenopharyngodon idella]
Length = 117
Score = 82.7 bits (203), Expect = 5e-16
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+ L VCG+RGF+++ T
Sbjct: 2 PETLCGAELVDTLQFVCGDRGFYFSKPTGYGPSSR-----------------------RS 38
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 39 HNRGIVDECCFQSCELRRLEMYC 61
>gi|124250|sp|P17085|IGF1_ONCKI INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|103868|pir||A41396 insulin-like growth factor I precursor, splice form 2 - coho salmon
gi|213432|gb|AAA49410.1| (M32792) insulin-like growth factor I precursor [Oncorhynchus
kisutch]
Length = 176
Score = 82.7 bits (203), Expect = 5e-16
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|2133793|pir||S66484 insulin-like growth factor II precursor - spiny dogfish
gi|2133794|pir||S58053 insulin-like growth factor II, precursor - spiny dogfish
gi|902733|emb|CAA90413.1| (Z50082) insulin-like growth factor II [Squalus acanthias]
Length = 210
Score = 82.7 bits (203), Expect = 6e-16
Identities = 35/104 (33%), Positives = 44/104 (41%), Gaps = 27/104 (25%)
Query: 7 LLPLLALLALWGP-DPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
+ PL LLAL + A + + LCGS LV+ L +C ERGF++ K
Sbjct: 33 VQPLCILLALTVCIGTSEARLEETLCGSELVDTLQFICAERGFYFVSKVVGR-------- 84
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
S Q RGIVE+CC C L LE YC
Sbjct: 85 ------------------RSRQNRGIVEECCFRSCDLLILETYC 110
>gi|213811|gb|AAA18211.1| (M81904) insulin-like growth factor I [Salmo salar]
Length = 145
Score = 82.7 bits (203), Expect = 6e-16
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 4 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 54
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 55 --------------RSHNRGIVDECCFQSCELRRLEMYC 79
>gi|729825|sp|Q02815|IGF1_ONCMY INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|422577|pir||A46244 insulin-like growth factor I precursor - rainbow trout
gi|213436|gb|AAA49412.1| (M95183) insulin-like growth factor I [Oncorhynchus mykiss]
Length = 176
Score = 82.7 bits (203), Expect = 6e-16
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|56435|emb|CAA29436.1| (X06043) IGF-IA precursor [Rattus norvegicus]
gi|204325|gb|AAA41227.1| (M17714) insulin-like growth factor-I precursor [Rattus norvegicus]
Length = 108
Score = 82.3 bits (202), Expect = 7e-16
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 23/87 (26%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 1 ATAGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ----------------- 43
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 44 ------TGIVDECCFRSCDLRRLEMYC 64
>gi|461660|sp|P33719|BXA2_SAMCY BOMBYXIN A-2 HOMOLOG PRECURSOR
gi|102955|pir||JQ0904 bombyxin A-2 homolog precursor - ailanthus silkmoth
gi|217384|dbj|BAA03021.1| (D13924) Samia bombyxin homolog A-2 [Samia cynthia]
Length = 100
Score = 82.3 bits (202), Expect = 7e-16
Identities = 28/105 (26%), Positives = 41/105 (38%), Gaps = 11/105 (10%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++L L+ +LA+ A V CG L L VC + P +
Sbjct: 4 QVLFLIVVLAVMASGDDTAHV---YCGRRLATMLLYVCDNQYQVKRPPYI-------SSE 53
Query: 66 VELGGGPGAGSLQPLALEGSLQKR-GIVEQCCTSICSLYQLENYC 109
E G + L+ + KR GIVE+CC C+ +L YC
Sbjct: 54 NEGYGWKWLERQRARQLDEARGKRQGIVEECCNKPCTENELLGYC 98
>gi|8571480|gb|AAF76900.1|AF276074_1 (AF276074) insulin-like growth factor 2 [Trichosurus vulpecula]
Length = 106
Score = 82.3 bits (202), Expect = 8e-16
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 23/88 (26%)
Query: 22 AAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLA 81
AA ++ LCG LV+ L VCG+RGF+++ R PL+
Sbjct: 2 AAYRPSETLCGGELVDTLQFVCGDRGFYFSLPGR-----------------------PLS 38
Query: 82 LEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIVE+CC C L LE YC
Sbjct: 39 RVSRRLNRGIVEECCFRSCDLALLETYC 66
>gi|345551|pir||A44012 insulin-like growth factor I prohormone (alternatively spliced)
proIGF-IA-1 - Oncorhynchus kisutch=coho salmon
(fragment)
gi|213439|gb|AAB59947.1| (M81911) insulin-like growth factor I [Oncorhynchus kisutch]
Length = 116
Score = 81.9 bits (201), Expect = 9e-16
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 4 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 54
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 55 --------------RSHNRGIVDECCFQSCELRRLEMYC 79
>gi|3687742|gb|AAC62228.1| (AF061278) insulin-like growth factor I [Paralichthys olivaceus]
Length = 186
Score = 81.9 bits (201), Expect = 9e-16
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPN----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELRRLEMYC 103
>gi|2894577|emb|CAA17123.1| (AL021880) insulin-like growth factor II precursor [Takifugu
rubripes]
Length = 215
Score = 81.9 bits (201), Expect = 1e-15
Identities = 31/109 (28%), Positives = 44/109 (39%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ L L L+ + + + LCG LV+AL VC +RGF+++ T R +
Sbjct: 29 MSSSSHALLFALALTLYVVEVTSI---ETLCGGELVDALQFVCEDRGFYFSRPTSRGSSR 85
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+CC C L +E YC
Sbjct: 86 RT------------------------QNRGIVEECCFRSCDLKLMEQYC 110
>gi|58145|emb|CAA28759.1| (X05113) synthetic somatomedin C (AA 1-113) [synthetic construct]
Length = 137
Score = 81.9 bits (201), Expect = 1e-15
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 69 PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 107
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 108 --TGIVDECCFRSCDLRRLEMYC 128
>gi|632198|pir||B54270 insulin-like growth factor-I precursor (clone OtIGFI-117B) -
chinook salmon
Length = 188
Score = 81.5 bits (200), Expect = 1e-15
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|224256|prf||1012293A insulin-like growth factor II precursor [Rattus norvegicus]
Length = 241
Score = 81.5 bits (200), Expect = 1e-15
Identities = 25/85 (29%), Positives = 35/85 (40%), Gaps = 27/85 (31%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
++ LCG LV+ L VC +RGF+++ + R
Sbjct: 1 RPSETLCGGELVDTLQFVCSDRGFYFSRPSGRAN-------------------------- 34
Query: 85 SLQKRGIVEQCCTSICSLYQLENYC 109
+ RGIVE+CC C L LE YC
Sbjct: 35 -RRSRGIVEECCFRSCDLALLETYC 58
>gi|2808535|emb|CAA11145.1| (AJ223165) IGF-II precursor [Taenopygia guttata]
Length = 187
Score = 81.5 bits (200), Expect = 1e-15
Identities = 35/103 (33%), Positives = 42/103 (39%), Gaps = 26/103 (25%)
Query: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66
LL LLA LA AA + LCG LV+ L VCG+RGF+++ R
Sbjct: 8 LLLLLAFLAYAMDSAAAYGTAETLCGGELVDTLQFVCGDRGFYFSRPVGRNN-------- 59
Query: 67 ELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIVE+CC C L LE YC
Sbjct: 60 ------------------RRFNRGIVEECCFRSCDLALLETYC 84
>gi|7438601|pir||T10897 insulin-like growth factor II precursor - chicken
gi|1836006|gb|AAB46818.1| (S82962) prepro-insulin-like growth factor-II; prepro-IGF-II
[Gallus gallus]
Length = 187
Score = 81.5 bits (200), Expect = 1e-15
Identities = 35/103 (33%), Positives = 42/103 (39%), Gaps = 26/103 (25%)
Query: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66
LL LLA LA AA + LCG LV+ L VCG+RGF+++ R
Sbjct: 8 LLLLLAFLAYALDSAAAYGTAETLCGGELVDTLQFVCGDRGFYFSRPVGRNN-------- 59
Query: 67 ELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIVE+CC C L LE YC
Sbjct: 60 ------------------RRINRGIVEECCFRSCDLALLETYC 84
>gi|632197|pir||A54270 insulin-like growth factor-I precursor (clone OtIGFI-117A) -
chinook salmon
gi|558940|gb|AAA67263.1| (U14536) insulin-like growth factor-I [Oncorhynchus tshawytscha]
gi|559007|gb|AAA67266.1| (U15960) insulin-like growth factor-I [Oncorhynchus tshawytscha]
Length = 188
Score = 81.5 bits (200), Expect = 1e-15
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|3176823|gb|AAC18833.1| (AF063216) insulin-like growth factor I precursor [Oncorhynchus
keta]
Length = 188
Score = 81.1 bits (199), Expect = 1e-15
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|2136466|pir||I53642 insulin-like growth factor II precursor - horse (fragment)
gi|508704|gb|AAA73915.1| (U11241) insulin-like growth factor II precursor [Equus caballus]
Length = 93
Score = 81.1 bits (199), Expect = 2e-15
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 27/87 (31%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 1 AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR-------------------------- 34
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 35 -INRRSRGIVEECCFRSCDLALLETYC 60
>gi|69309|pir||INSH insulin precursor - sheep
Length = 77
Score = 81.1 bits (199), Expect = 2e-15
Identities = 61/86 (70%), Positives = 64/86 (73%), Gaps = 9/86 (10%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK E E QVG +EL GGPGAG L+
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA--EVEGPQVGALELAGGPGAGGLEGPPQ-- 56
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC +CSLYQLENYCN
Sbjct: 57 -----GIVEQCCAGVCSLYQLENYCN 77
>gi|224501|prf||1106261A insulin-like growth factor II variant [Homo sapiens]
Length = 90
Score = 80.7 bits (198), Expect = 2e-15
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 25/87 (28%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VCG+RGF+++ +
Sbjct: 1 AYRPSETLCGGELVDTLQFVCGDRGFYFSRPACGD------------------------- 35
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 36 RVSRRSRGIVEECCFRSCDLALLETYC 62
>gi|5103031|dbj|BAA78767.1| (AB028636) IGF1 [Mesocricetus auratus]
Length = 88
Score = 80.7 bits (198), Expect = 2e-15
Identities = 28/94 (29%), Positives = 39/94 (40%), Gaps = 23/94 (24%)
Query: 16 LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAG 75
L +A + LCG+ LV+AL VCG RGF++ T + + Q
Sbjct: 1 LLTFTSSATAGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQ---------- 50
Query: 76 SLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 51 -------------TGIVDECCFRSCDLRRLEMYC 71
>gi|1364191|emb|CAA37620.1| (X53553) insulin-like growth factor II, partial (AA 1-150) (1 is
3rd base in codon) [Bos taurus]
Length = 150
Score = 80.7 bits (198), Expect = 2e-15
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 27/82 (32%)
Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 87
+ LCG LV+ L VCG+RGF+++ + R + +
Sbjct: 1 ETLCGGELVDTLQFVCGDRGFYFSRPSSR---------------------------INRR 33
Query: 88 KRGIVEQCCTSICSLYQLENYC 109
RGIVE+CC C L LE YC
Sbjct: 34 SRGIVEECCFRSCDLALLETYC 55
>gi|1808660|emb|CAA71789.1| (Y10830) prepro insulin-like growth factor I [Oreochromis
mossambicus]
Length = 182
Score = 80.7 bits (198), Expect = 2e-15
Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFNKPTGYGPS----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELQRLEMYC 103
>gi|1170518|sp|P41694|IGF2_MUSVI INSULIN-LIKE GROWTH FACTOR II PRECURSOR (IGF-II)
gi|13325097|gb|AAB27392.2| (S63459) insulin-like growth factor II precursor; proIGF-II
[Mustela vison]
Length = 129
Score = 80.7 bits (198), Expect = 2e-15
Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 26/108 (24%)
Query: 2 ALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDL 61
+ LL L LAL AA ++ LCG LV+ L VCG+RGF++
Sbjct: 4 PMGKSLLAPLTFLALASCCFAAYRPSETLCGGELVDTLQFVCGDRGFYF----------- 52
Query: 62 QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+P + RGIVE+CC C L LE YC
Sbjct: 53 ---------------SRPASRVSRRSSRGIVEECCFRSCDLALLETYC 85
>gi|488155|gb|AAA18212.1| (M81904) insulin-like growth factor I [Salmo salar]
Length = 117
Score = 80.7 bits (198), Expect = 2e-15
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 4 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 54
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 55 --------------RSHNRGIVDECCFQSCELRRLEMYC 79
>gi|3158361|gb|AAC17494.1| (AF033800) insulin-like growth factor I [Oreochromis mossambicus]
Length = 182
Score = 80.7 bits (198), Expect = 2e-15
Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFNKPTGYGPS----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELQRLEMYC 103
>gi|69352|pir||IPRYM insulin precursor - marbled electric ray (fragments)
Length = 68
Score = 80.4 bits (197), Expect = 3e-15
Identities = 37/85 (43%), Positives = 45/85 (52%), Gaps = 18/85 (21%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
+QHLCGSHLVEALY VCG +GF+Y PK + SL + +
Sbjct: 2 PSQHLCGSHLVEALYFVCGPKGFYYLPKAFVD------------------SLAGYSKHQN 43
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIVE CC + CSL+ LE YCN
Sbjct: 44 GGISGIVEHCCHNTCSLFDLEGYCN 68
>gi|2625161|gb|AAB86652.1| (AF033796) insulin-like growth factor I precursor [Oreochromis
mossambicus]
Length = 182
Score = 80.4 bits (197), Expect = 3e-15
Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFNKPTGYGPS----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELQRLEMYC 103
>gi|115182|sp|P26742|BXB8_BOMMO BOMBYXIN B-8 PRECURSOR (BBX-B8) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102908|pir||JQ0833 bombyxin B-8 - silkworm
gi|2133601|pir||S69489 bombyxin B-8 precursor - silkworm
gi|217242|dbj|BAA00680.1| (D00784) bombyxin B-8 precursor [Bombyx mori]
Length = 88
Score = 80.4 bits (197), Expect = 3e-15
Identities = 31/104 (29%), Positives = 44/104 (41%), Gaps = 20/104 (19%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L +L L A V + CGSHL + L +C G
Sbjct: 4 SVIFVLIVLNLMWSGEAQ-EVARTYCGSHLADTLADLC-------------------FGV 43
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V+ GG A A GS KRG+V++CC C+L L +YC
Sbjct: 44 VKRGGAQYAPYFWQKAYLGSRGKRGVVDECCFRPCTLDVLASYC 87
>gi|3776078|emb|CAA08766.1| (AJ009655) insulin [Homo sapiens]
Length = 59
Score = 80.0 bits (196), Expect = 3e-15
Identities = 59/59 (100%), Positives = 59/59 (100%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE
Sbjct: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
>gi|2143806|pir||I52680 insulin-like growth factor II - rat (fragment)
gi|204926|gb|AAA41433.1| (M38688) insulin-like growth factor II [Rattus norvegicus]
Length = 154
Score = 80.0 bits (196), Expect = 4e-15
Identities = 25/85 (29%), Positives = 35/85 (40%), Gaps = 27/85 (31%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
++ LCG LV+ L VC +RGF+++ + R
Sbjct: 1 RPSETLCGGELVDTLQFVCSDRGFYFSRPSGRAN-------------------------- 34
Query: 85 SLQKRGIVEQCCTSICSLYQLENYC 109
+ RGIVE+CC C L LE YC
Sbjct: 35 -RRSRGIVEECCFRSCDLALLETYC 58
>gi|632199|pir||C54270 insulin-like growth factor-I precursor (clone OtIGFI-36) - chinook
salmon
gi|559009|gb|AAA67267.1| (U15961) insulin-like growth factor-I [Oncorhynchus tshawytscha]
Length = 161
Score = 80.0 bits (196), Expect = 4e-15
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCDLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|115175|sp|P26733|BXB1_BOMMO BOMBYXIN B-1 PRECURSOR (BBX-B1) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
Length = 89
Score = 80.0 bits (196), Expect = 4e-15
Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 19/104 (18%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L ++ A V + CG HL + L +C G
Sbjct: 4 SVMFMLVIVISLMCSGEAQEVARTYCGRHLADTLADLC-------------------FGV 44
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ GG A GS KRG+V++CC C+L L +YC
Sbjct: 45 EKRGGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 88
>gi|69357|pir||IPMTB1 bombyxin B-1 precursor - silkworm
gi|155963|gb|AAA27824.1| (M26068) bombysin B-1 [Bombyx mori]
Length = 90
Score = 79.6 bits (195), Expect = 4e-15
Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 19/104 (18%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L ++ A V + CG HL + L +C G
Sbjct: 5 SVMFMLVIVISLMCSGEAQEVARTYCGRHLADTLADLC-------------------FGV 45
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ GG A GS KRG+V++CC C+L L +YC
Sbjct: 46 EKRGGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 89
>gi|4104007|gb|AAD01917.1| (AF030573) prepro-insulin-like growth factor I [Acanthopagrus
schlegeli]
Length = 185
Score = 79.6 bits (195), Expect = 4e-15
Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 26/99 (26%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ G
Sbjct: 30 LLLCVLTLTPTATGASPETLCGAELVDTLQFVCGERGFYFSKP---------------GY 74
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
GP A + RGIV++CC C L +LE YC
Sbjct: 75 GPNA-----------RRSRGIVDECCFQSCELRRLEMYC 102
>gi|2569961|emb|CAA73162.1| (Y12583) insulin-like growth factor [Myoxocephalus scorpius]
Length = 184
Score = 79.6 bits (195), Expect = 4e-15
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ G
Sbjct: 30 LLLCVLTLSLTATRAGPETLCGAELVDTLQFVCGERGFYFSKP----------------G 73
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
G G + + RGIV++CC C L +LE YC
Sbjct: 74 GYGPN---------ARRSRGIVDECCFQSCELRRLEMYC 103
>gi|115176|sp|P26734|BXB2_BOMMO BOMBYXIN B-2 PRECURSOR (BBX-B2) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
Length = 89
Score = 79.6 bits (195), Expect = 5e-15
Identities = 25/104 (24%), Positives = 38/104 (36%), Gaps = 19/104 (18%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L + A V + CG HL + L +C G
Sbjct: 4 SVMFMLVFVISLMCSSEAQEVARTYCGRHLADTLADLC-------------------FGV 44
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ G A GS KRG+V++CC C+L L +YC
Sbjct: 45 EKRSGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 88
>gi|69358|pir||IPMTB2 bombyxin B-2 precursor - silkworm
gi|155966|gb|AAA27826.1| (M26069) bombyxin B-2 [Bombyx mori]
Length = 90
Score = 79.6 bits (195), Expect = 5e-15
Identities = 25/104 (24%), Positives = 38/104 (36%), Gaps = 19/104 (18%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L + A V + CG HL + L +C G
Sbjct: 5 SVMFMLVFVISLMCSSEAQEVARTYCGRHLADTLADLC-------------------FGV 45
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ G A GS KRG+V++CC C+L L +YC
Sbjct: 46 EKRSGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 89
>gi|115186|sp|P26735|BXC2_BOMMO BOMBYXIN C-2 PRECURSOR (BBX-C2) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102912|pir||JQ0839 bombyxin C-2 - silkworm
gi|2133604|pir||S69498 bombyxin C-2 precursor - silkworm
gi|217256|dbj|BAA00688.1| (D00792) bombyxin C-2 precursor [Bombyx mori]
Length = 95
Score = 79.6 bits (195), Expect = 5e-15
Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 16/106 (15%)
Query: 5 MRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVG 64
M+L+ LL +++ A +Q CG L + ++C D+
Sbjct: 1 MKLVILLVVVSAMLVLGGAQTASQFYCGDFLARTMSILCWP--------------DMPKR 46
Query: 65 QVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
G G L P + S KRGIV++CC C+ L+ YC+
Sbjct: 47 SGSQYAGYGWPWLPPFSS--SRGKRGIVDECCYRPCTTDVLKLYCD 90
>gi|632196|pir||D54270 insulin-like growth factor-I precursor (clone OtIGFI-0) - chinook
salmon
gi|559011|gb|AAA67268.1| (U15962) insulin-like growth factor-I [Oncorhynchus tshawytscha]
Length = 149
Score = 79.6 bits (195), Expect = 5e-15
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTSAATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPSSR--------- 80
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 81 --------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|115184|sp|P15410|BXC1_BOMMO BOMBYXIN C-1 PRECURSOR (BBX-C1) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|280587|pir||A60296 bombyxin C-1 precursor - silkworm
gi|2133603|pir||S69497 bombyxin C-1 precursor - silkworm
gi|217252|dbj|BAA00686.1| (D00790) bombyxin C-1 precursor [Bombyx mori]
gi|217254|dbj|BAA00687.1| (D00791) bombyxin C-1 precursor [Bombyx mori]
gi|227979|prf||1714254A bombyxin C1 [Bombyx mori]
Length = 91
Score = 79.2 bits (194), Expect = 6e-15
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 16/106 (15%)
Query: 5 MRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVG 64
M+L+ LL +++ A +Q CG L + +C D+Q
Sbjct: 1 MKLVMLLVVVSAMLVLGGAQTASQFYCGDFLARTMSSLCW--------------SDMQKR 46
Query: 65 QVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
G G L P + S KRGIV++CC C++ L +YC+
Sbjct: 47 SGSQYAGYGWPWLPPFSS--SRGKRGIVDECCYRPCTIDVLMSYCD 90
>gi|9664869|gb|AAF97244.1|AF283002_1 (AF283002) insulin-like growth factor 2 [Bos indicus]
Length = 149
Score = 79.2 bits (194), Expect = 6e-15
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 27/81 (33%)
Query: 29 HLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQK 88
LCG LV+ L VCG+RGF+++ + R + +
Sbjct: 1 TLCGGELVDTLQFVCGDRGFYFSRPSSR---------------------------INRRS 33
Query: 89 RGIVEQCCTSICSLYQLENYC 109
RGIVE+CC C L LE YC
Sbjct: 34 RGIVEECCFRSCDLALLETYC 54
>gi|2736077|gb|AAB94052.1| (AF016922) insulin-like growth factor I [Paralichthys olivaceus]
Length = 185
Score = 79.2 bits (194), Expect = 7e-15
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPN----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELRRLEMYC 103
>gi|115181|sp|P26741|BXB7_BOMMO BOMBYXIN B-7 PRECURSOR (BBX-B7) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102906|pir||JQ0831 bombyxin B-7 - silkworm strain Kinshu
gi|2133600|pir||S69488 bombyxin B-7 precursor - silkworm (strain Kinshu)
gi|217238|dbj|BAA00678.1| (D00782) bombyxin B-7 precursor [Bombyx mori]
Length = 90
Score = 78.8 bits (193), Expect = 8e-15
Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 19/104 (18%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L ++ A V + CG HL + L +C G
Sbjct: 5 SVMLMLVVVISLMCSGEAQEVARTYCGRHLADTLADLC-------------------FGV 45
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ GG A GS KRG+V++CC C+L L +YC
Sbjct: 46 EKRGGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 89
>gi|3483058|emb|CAA09268.1| (AJ010603) preproinsulin-like growth factor Ib [Paralichthys
olivaceus]
Length = 186
Score = 78.8 bits (193), Expect = 8e-15
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ VCGERGF+++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTPQFVCGERGFYFSKPTGYGPN----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELRRLEMYC 103
>gi|115178|sp|P26738|BXB4_BOMMO BOMBYXIN B-4 PRECURSOR (BBX-B4) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102903|pir||JQ0828 bombyxin B-4 - silkworm
gi|2133596|pir||S69485 bombyxin B-4 precursor - silkworm
gi|217232|dbj|BAA00675.1| (D00779) bombyxin B-4 precursor [Bombyx mori]
Length = 90
Score = 78.4 bits (192), Expect = 1e-14
Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 19/103 (18%)
Query: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66
++ +L ++ A V + CG HL + L +C G
Sbjct: 6 VMFMLVVVINLMCSGEAQEVARTYCGRHLADTLADLC-------------------FGVE 46
Query: 67 ELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ G A GS KRG+V++CC C+L L +YC
Sbjct: 47 KRSGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 89
>gi|3483056|emb|CAA09267.1| (AJ010602) preproinsulin-like growth factor Ia [Paralichthys
olivaceus]
Length = 159
Score = 78.4 bits (192), Expect = 1e-14
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 25/99 (25%)
Query: 11 LALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGG 70
L L L A + LCG+ LV+ L VCGERGF+++ T
Sbjct: 30 LLLCVLTLTPTATGAGPETLCGAELVDTLQFVCGERGFYFSKPTGYGPN----------- 78
Query: 71 GPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIV++CC C L +LE YC
Sbjct: 79 --------------ARRSRGIVDECCFQSCELRRLEMYC 103
>gi|6319169|gb|AAF07193.1|AF194333_1 (AF194333) insulin-like growth factor 2 precursor [Danio rerio]
Length = 197
Score = 78.4 bits (192), Expect = 1e-14
Identities = 30/105 (28%), Positives = 39/105 (36%), Gaps = 28/105 (26%)
Query: 5 MRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVG 64
MR L + L A + LCG LV+ L VCGE GF+ + R
Sbjct: 21 MRSLIVFVLSLSMLISNVTAG--ETLCGGELVDTLQFVCGEDGFYISRPNR--------- 69
Query: 65 QVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+RGIVE+CC C L+ L+ YC
Sbjct: 70 -----------------SNSRRPQRGIVEECCFRSCELHLLQQYC 97
>gi|11275220|pir||PC7082 epidermal growth factor/single chain insulin fusion protein -
Bacillus brevis (fragment)
Length = 96
Score = 78.4 bits (192), Expect = 1e-14
Identities = 50/96 (52%), Positives = 51/96 (53%), Gaps = 36/96 (37%)
Query: 15 ALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGA 74
+ FVNQHLCGSHLVEALYLVCGERGFFYTPK
Sbjct: 37 VSMYIEALDKFVNQHLCGSHLVEALYLVCGERGFFYTPK--------------------- 75
Query: 75 GSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCCTSICSLYQLENYCN
Sbjct: 76 ---------------GIVEQCCTSICSLYQLENYCN 96
>gi|102907|pir||JQ0832 bombyxin B-7 - silkworm strain Showa
gi|2133599|pir||S69487 bombyxin B-7 precursor - silkworm (strain Showa)
gi|217240|dbj|BAA00679.1| (D00783) bombyxin B-7 precursor [Bombyx mori]
Length = 90
Score = 78.4 bits (192), Expect = 1e-14
Identities = 24/104 (23%), Positives = 39/104 (37%), Gaps = 19/104 (18%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L ++ A V + CG HL + L +C G
Sbjct: 5 SVMLMLVVVISLICSGEAQEVARTYCGRHLADTLADLC-------------------FGV 45
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ G A G+ KRG+V++CC C+L L +YC
Sbjct: 46 EKRSGAQYAPYFWTRQHLGNRGKRGVVDECCFRPCTLDVLLSYC 89
>gi|102895|pir||JQ0816 bombyxin A-7 - silkworm strain Showa
gi|2133587|pir||S69481 bombyxin A-7 precursor - silkworm (strain Showa)
gi|217220|dbj|BAA00669.1| (D00773) bombyxin A-7 precursor [Bombyx mori]
Length = 92
Score = 78.4 bits (192), Expect = 1e-14
Identities = 28/107 (26%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M+LL +AL+ + CG HL L +C E G
Sbjct: 1 MKLLLAIALMLTIVMWVSTQQPQAVHTYCGRHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + KRGIV++CC CS+ L +YC
Sbjct: 46 VDKRSDAQFASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC 92
>gi|208030|gb|AAA72971.1| (M60420) insulin-like growth factor 2 [synthetic construct]
Length = 69
Score = 78.1 bits (191), Expect = 1e-14
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 27/89 (30%)
Query: 21 PAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPL 80
AA ++ LCG LV+ L VCG+RGF+++ + R
Sbjct: 1 MAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSR------------------------ 36
Query: 81 ALEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 37 ---INRRSRGIVEECCFRSCDLALLETYC 62
>gi|2289113|gb|AAB64356.1| (U82395) proinsulin [Callorhinchus milii]
Length = 74
Score = 78.1 bits (191), Expect = 1e-14
Identities = 35/74 (47%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 40 YLVCGERGFFYTPKTRREAEDLQVGQ---VELGGGPGAGSLQPLALEGSLQKRGIVEQCC 96
Y VCGERGFFY+PK R+ L + L L GS KRGIVEQCC
Sbjct: 1 YFVCGERGFFYSPKQIRDVGPLSAFRDLEPPLDTEMEDRFPYRQQLAGSKMKRGIVEQCC 60
Query: 97 TSICSLYQLENYCN 110
+ CSL LE YCN
Sbjct: 61 HNTCSLVNLEGYCN 74
>gi|3127060|gb|AAC78289.1| (AF050524) proinsulin-like protein BKRA [synthetic construct]
Length = 54
Score = 77.7 bits (190), Expect = 2e-14
Identities = 53/86 (61%), Positives = 53/86 (61%), Gaps = 33/86 (38%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Sbjct: 2 FVNQHLCGSHLVEALYLVCGERGFFYTPKT------------------------------ 31
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
KRGIVEQCCTSICSLYQLENYCN
Sbjct: 32 ---KRGIVEQCCTSICSLYQLENYCN 54
>gi|2655872|emb|CAA04657.1| (AJ001297) IGF2 protein [Callithrix jacchus]
Length = 72
Score = 77.3 bits (189), Expect = 2e-14
Identities = 29/88 (32%), Positives = 37/88 (41%), Gaps = 27/88 (30%)
Query: 22 AAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLA 81
AA + LCG LV+ L VCG+RGF+++ R
Sbjct: 2 AAYRPRETLCGGELVDTLQFVCGDRGFYFSRPASR------------------------- 36
Query: 82 LEGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 37 --VSRRSRGIVEECCFRSCDLALLETYC 62
>gi|9972779|sp|Q17194|BXBA_BOMMO BOMBYXIN B-10 PRECURSOR (BBX-B10) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102899|pir||JQ0836 bombyxin B-10 - silkworm
gi|2133592|pir||S72663 bombyxin B-10 precursor - silkworm
gi|217228|dbj|BAA00683.1| (D00787) bombyxin B-10 precursor [Bombyx mori]
Length = 87
Score = 77.3 bits (189), Expect = 2e-14
Identities = 26/103 (25%), Positives = 38/103 (36%), Gaps = 20/103 (19%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L L +++L A V CG HL + L +C G +
Sbjct: 5 LIFLVVISLMYSGEAQ-EVAHTYCGRHLADTLADLC-------------------FGVEK 44
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 110
G A GS KR +V++CC C+L L +YC+
Sbjct: 45 RSGAQYAPYFWTRQYLGSRGKRSVVDECCFRPCTLDVLLSYCD 87
>gi|227567|prf||1707201B insulin-like growth factor 2 [Sus scrofa domestica]
Length = 67
Score = 77.3 bits (189), Expect = 3e-14
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 27/87 (31%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 1 AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR-------------------------- 34
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 35 -VNRRSRGIVEECCFRSCDLALLETYC 60
>gi|3982553|gb|AAC83443.1| (AF001005) insulin-like growth factor-I [Carassius auratus]
Length = 161
Score = 76.9 bits (188), Expect = 3e-14
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 28/110 (25%)
Query: 5 MRLLP-----LLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
MR L L L L + LCG+ LV+ L VCG+RGF+++ T
Sbjct: 19 MRCLSCTHTLSLLLCVLALTPATLEAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGPN 78
Query: 60 DLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 79 SR-----------------------RSHNRGIVDECCFQSCELRRLEMYC 105
>gi|115180|sp|P26740|BXB6_BOMMO BOMBYXIN B-6 PRECURSOR (BBX-B6) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102905|pir||JQ0830 bombyxin B-6 - silkworm
gi|2133598|pir||S69486 bombyxin B-6 precursor - silkworm
gi|217236|dbj|BAA00677.1| (D00781) bombyxin B-6 precursor [Bombyx mori]
Length = 90
Score = 76.9 bits (188), Expect = 3e-14
Identities = 25/104 (24%), Positives = 38/104 (36%), Gaps = 19/104 (18%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++ +L ++ A V + CG L + L +C E V Q
Sbjct: 5 SVMFMLVVVISLMCSSEAQEVARTYCGRDLADTLADLC------------FGVEKRGVAQ 52
Query: 66 VELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
A GS KRG+V++CC C+L L +YC
Sbjct: 53 Y-------APYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 89
>gi|738556|prf||2001274C insulin-like growth factor II [Odocoileus sp.]
Length = 67
Score = 76.9 bits (188), Expect = 3e-14
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 27/87 (31%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VCG+RGF+++ + R
Sbjct: 1 AYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSR-------------------------- 34
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 35 -INRRSRGIVEECCFRSCDLALLETYC 60
>gi|9973400|sp|Q28933|IGF1_SUNMU INSULIN-LIKE GROWTH FACTOR I PRECURSOR (IGF-I) (SOMATOMEDIN)
gi|1304229|dbj|BAA07897.1| (D43957) insulin-like growth factor I precursor [Suncus murinus]
Length = 81
Score = 76.9 bits (188), Expect = 3e-14
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 23/87 (26%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A+ + LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 2 ASAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ----------------- 44
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 45 ------TGIVDECCFRSCDLRRLEMYC 65
>gi|115171|sp|P26730|BXA7_BOMMO BOMBYXIN A-7 PRECURSOR (BBX-A7) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102894|pir||JQ0824 bombyxin A-7 - silkworm strain Kinshu
gi|2133588|pir||S69482 bombyxin A-7 precursor - silkworm (strain Kinshu)
gi|217218|dbj|BAA00668.1| (D00772) bombyxin A-7 precursor [Bombyx mori]
Length = 92
Score = 76.5 bits (187), Expect = 4e-14
Identities = 28/107 (26%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M+LL +AL+ + CG HL L +C E G
Sbjct: 1 MKLLLAIALMLTIVMWVSTQQPQAVHTYCGRHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + KRGIV++CC CS+ L +YC
Sbjct: 46 VDKRSDAQYASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC 92
>gi|1000058|pdb|1IGL| Insulin-Like Growth Factor Ii (Igf-Ii, Igf-2) (Nmr, 20
Structures)
gi|1449482|prf||0407244A:PDB=1GF2 insulin-like growth factor II [Homo sapiens]
Length = 67
Score = 76.5 bits (187), Expect = 4e-14
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 27/87 (31%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 1 AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR-------------------------- 34
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
S + RGIVE+CC C L LE YC
Sbjct: 35 -VSRRSRGIVEECCFRSCDLALLETYC 60
>gi|738557|prf||2001274D insulin-like growth factor II [Ovis aries]
Length = 67
Score = 76.5 bits (187), Expect = 4e-14
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 27/87 (31%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VCG+RGF+++ + R
Sbjct: 1 AYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSR-------------------------- 34
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 35 -INRRSRGIVEECCFRSCDLALLETYC 60
>gi|115170|sp|P26729|BXA6_BOMMO BOMBYXIN A-6 PRECURSOR (BBX-A6) (BOMBYXIN-II)
(4K-PROTHORACICOTROPIC HORMONE) (4K-PTTH)
gi|102893|pir||JQ0823 bombyxin A-6 - silkworm
gi|2133586|pir||S69478 bombyxin A-6 precursor - silkworm
gi|217216|dbj|BAA00667.1| (D00771) bombyxin A-6 precursor [Bombyx mori]
Length = 92
Score = 76.1 bits (186), Expect = 5e-14
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M++L +AL+ + CG HL L +C E G
Sbjct: 1 MKILLAIALMLSTVMWVSTQQPQAVHTYCGRHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + KRGIV++CC CS+ L +YC
Sbjct: 46 VDKRSGAQFASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC 92
>gi|115177|sp|P26737|BXB3_BOMMO BOMBYXIN B-3 PRECURSOR (BBX-B3) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102902|pir||JQ0827 bombyxin B-3 - silkworm
gi|2133595|pir||S69491 bombyxin B-3 precursor - silkworm
gi|217230|dbj|BAA00674.1| (D00778) bombyxin B-3 precursor [Bombyx mori]
Length = 90
Score = 76.1 bits (186), Expect = 5e-14
Identities = 24/102 (23%), Positives = 37/102 (35%), Gaps = 19/102 (18%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
+ +L ++ V + CG+HL L +C G +
Sbjct: 7 MFMLVVVISLTYSSEEQEVARTYCGAHLANTLADLC-------------------FGVEK 47
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
G A GS KRG+V++CC C+L L +YC
Sbjct: 48 RSGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYC 89
>gi|115168|sp|P26727|BXA4_BOMMO BOMBYXIN A-4 PRECURSOR (BBX-A4) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102891|pir||JQ0814 bombyxin A-4 - silkworm
gi|2133583|pir||S69477 bombyxin A-4 precursor - silkworm
gi|217212|dbj|BAA00665.1| (D00769) bombyxin A-4 precursor [Bombyx mori]
Length = 92
Score = 76.1 bits (186), Expect = 6e-14
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M++L +AL+ + CG HL L +C E G
Sbjct: 1 MKILLAIALMLSTVMWVSTQQPQGVHTYCGRHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + KRGIV++CC CS+ L +YC
Sbjct: 46 VDKRSGAQFASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC 92
>gi|738554|prf||2001274A insulin-like growth factor I [Odocoileus sp.]
Length = 70
Score = 76.1 bits (186), Expect = 6e-14
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 2 PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|5107517|pdb|1BQT| Three-Dimensional Structure Of Human Insulin-Like Growth Factor-I
(Igf-I) Determined By 1h-Nmr And Distance Geometry, 6
Structures
gi|349927|pdb|2GF1| Insulin-Like Growth Factor (Nmr, Minimum Average Structure)
gi|349941|pdb|3GF1| Insulin-Like Growth Factor (Nmr, 10 Structures)
gi|208427|gb|AAA72204.1| (J03741) insulin-like growth factor [synthetic construct]
gi|4261909|gb|AAD14209.1|S76122_1 (S76122) insulin-like growth factor 1 [Bos taurus]
gi|223813|prf||0912651A somatomedin C [Homo sapiens]
Length = 70
Score = 75.7 bits (185), Expect = 8e-14
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 2 PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|209366|gb|AAA72455.1| (M10170) synthetic somatomedin-C/insulin-like growth factor I
[synthetic construct]
Length = 71
Score = 75.4 bits (184), Expect = 8e-14
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 3 PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 41
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 42 --TGIVDECCFRSCDLRRLETYC 62
>gi|231658|sp|P29519|BXBC_BOMMO BOMBYXIN B-12 PRECURSOR (BBX-B12) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102901|pir||JQ0838 bombyxin B-12 - silkworm
gi|2133594|pir||S69492 bombyxin B-12 precursor - silkworm
gi|217250|dbj|BAA00685.1| (D00789) bombyxin B-12 precursor [Bombyx mori]
Length = 90
Score = 75.4 bits (184), Expect = 8e-14
Identities = 24/102 (23%), Positives = 37/102 (35%), Gaps = 19/102 (18%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
+ +L ++ V + CG+HL L +C G +
Sbjct: 7 MFMLVVVISLTYSSEEQEVARTYCGAHLANTLADLC-------------------FGVEK 47
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
G A GS KRG+V++CC C+L L +YC
Sbjct: 48 RSGAQYAPYFWTRQYLGSRGKRGVVDECCFQPCTLDVLLSYC 89
>gi|109033|pir||S07198 insulin-like growth factor - sheep
gi|738555|prf||2001274B insulin-like growth factor I [Ovis aries]
Length = 70
Score = 75.4 bits (184), Expect = 8e-14
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 2 PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|208526|gb|AAA72579.1| (M16249) insulin-like growth factor [synthetic construct]
gi|208675|gb|AAA72763.1| (M26100) synthetic insulin-like growth factor [synthetic construct]
gi|220973|dbj|BAA01200.1| (D10367) Met-somatomedin C polypeptide [synthetic construct]
Length = 71
Score = 75.4 bits (184), Expect = 8e-14
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 3 PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 41
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 42 --TGIVDECCFRSCDLRRLEMYC 62
>gi|69349|pir||INFI insulin precursor - spotted ratfish (fragments)
gi|69350|pir||INRQ insulin - rabbit fish (tentative sequence)
Length = 59
Score = 75.4 bits (184), Expect = 9e-14
Identities = 41/85 (48%), Positives = 44/85 (51%), Gaps = 27/85 (31%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
Q LCGSHLV+ALY VCGERGFFY+PK RE E L
Sbjct: 2 PTQRLCGSHLVDALYFVCGERGFFYSPKPIRELEPLL----------------------- 38
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC + CSL LE YCN
Sbjct: 39 ----GIVEQCCHNTCSLANLEGYCN 59
>gi|208429|gb|AAA72201.1| (J03738) insulin-like growth factor I [synthetic construct]
Length = 70
Score = 75.4 bits (184), Expect = 9e-14
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+ALYLVCG+RGF++ T + + Q
Sbjct: 2 PETLCGAELVDALYLVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|9972776|sp|Q17192|BXA1_BOMMO BOMBYXIN A-1 PRECURSOR (BBX-A1) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|482534|pir||A48322 bombyxin A-1 precursor - silkworm
gi|217208|dbj|BAA00246.1| (D00340) bombyxin [Bombyx mori]
gi|226562|prf||1602144A bombyxin [Bombyx mori]
Length = 92
Score = 75.4 bits (184), Expect = 1e-13
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M++L +AL+ + CG HL L +C E G
Sbjct: 1 MKILLAIALMLSTVMWVSTQQPQRVHTYCGRHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + KRGIV++CC CS+ L +YC
Sbjct: 46 VDKRSGAQFASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC 92
>gi|146446|gb|AAA53535.1| (M22044) insulin-like growth factor I [synthetic construct]
Length = 70
Score = 75.0 bits (183), Expect = 1e-13
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 2 PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAAQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|461659|sp|P33718|BXA1_SAMCY BOMBYXIN A-1 HOMOLOG PRECURSOR
gi|102954|pir||JQ0902 bombyxin A-1 homolog - ailanthus silkmoth
gi|217381|dbj|BAA03019.1| (D13923) Samia bombyxin homolog A-1 [Samia cynthia]
Length = 99
Score = 75.0 bits (183), Expect = 1e-13
Identities = 26/105 (24%), Positives = 37/105 (34%), Gaps = 10/105 (9%)
Query: 6 RLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQ 65
++L L+ LA A CG L L VC + +
Sbjct: 4 QVLFLVFALAAVMVSGDAT--PHVYCGRRLATMLSFVCDNQYQVKRTPYI-------SPE 54
Query: 66 VELGGGPGAGSLQPLALEGSLQKR-GIVEQCCTSICSLYQLENYC 109
E G + L+G+ KR GI E+CC C+ +L YC
Sbjct: 55 NEGYGWRWLEPQRARQLDGARGKRQGIAEECCNKPCTENELLGYC 99
>gi|2133584|pir||S69479 bombyxin A-5 precursor - silkworm
Length = 92
Score = 75.0 bits (183), Expect = 1e-13
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M+LL +AL+ + CG HL L +C E G
Sbjct: 1 MKLLLAIALMLTTVMWASTQQPQTVHTYCGRHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + +RGIV++CC CS+ L +YC
Sbjct: 46 VDKRSDAQFASYGSAWLMPYSEGRDQRGIVDECCLRPCSVDVLLSYC 92
>gi|115173|sp|P26732|BXA9_BOMMO BOMBYXIN A-9 PRECURSOR (BBX-A9) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102898|pir||JQ0825 bombyxin A-9 precursor - silkworm
gi|217226|dbj|BAA00672.1| (D00776) bombyxin A-9 precursor [Bombyx mori]
Length = 92
Score = 75.0 bits (183), Expect = 1e-13
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M+LL +AL+ + CG HL L +C E G
Sbjct: 1 MKLLLAIALMLTTVMWASTQQPQAVHTYCGRHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + +RGIV++CC CS+ L +YC
Sbjct: 46 VDKRSDAQFASYGSAWLMPYSEGRDQRGIVDECCLRPCSVDVLLSYC 92
>gi|85535|pir||S09146 insulin II precursor - chum salmon (fragment)
Length = 66
Score = 74.6 bits (182), Expect = 1e-13
Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
Query: 44 GERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL-QKRGIVEQCCTSICSL 102
GE+GFFY PK R+ + L + P + + KRGIVE+CC C++
Sbjct: 1 GEKGFFYNPK--RDVDPLIGFLSPKSSQENEVAEYPFKDQMDMIVKRGIVEECCHKPCNI 58
Query: 103 YQLENYCN 110
+ L+NYCN
Sbjct: 59 FDLQNYCN 66
>gi|2133591|pir||S69490 bombyxin B-10 precursor - silkworm
Length = 87
Score = 74.6 bits (182), Expect = 1e-13
Identities = 26/102 (25%), Positives = 38/102 (36%), Gaps = 20/102 (19%)
Query: 8 LPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVE 67
L L +++L A V + CG HL + L +C G +
Sbjct: 5 LIFLVVISLMYSGEAQ-EVARTYCGRHLADTLADLC-------------------FGVEK 44
Query: 68 LGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
G A GS KR +V++CC C+L L +YC
Sbjct: 45 RSGAQYAPYFWTRQYLGSRGKRSVVDECCFRPCTLDVLLSYC 86
>gi|213447|gb|AAA49415.1| (K03487) preproinsulin [Oncorhynchus keta]
gi|225447|prf||1303322B insulin [Oncorhynchus keta]
Length = 66
Score = 74.6 bits (182), Expect = 2e-13
Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
Query: 44 GERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL-QKRGIVEQCCTSICSL 102
GE+GFFY PK R+ + L + P + + KRGIVEQCC C++
Sbjct: 1 GEKGFFYNPK--RDVDPLIGFLSPKSSQENEVAEYPFKDQMDMIVKRGIVEQCCHKPCNI 58
Query: 103 YQLENYCN 110
+ L+NYCN
Sbjct: 59 FDLQNYCN 66
>gi|2808466|emb|CAA76136.1| (Y16248) IGF-1 [Bubalus bubalis]
Length = 70
Score = 74.2 bits (181), Expect = 2e-13
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+A VCG RGF++ T + + Q
Sbjct: 2 PETLCGAELVDAFQFVCGPRGFYFNKPTGYGSSIRRAPQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|109123|pir||S08567 insulin-like growth factor - sheep
Length = 67
Score = 74.2 bits (181), Expect = 2e-13
Identities = 26/87 (29%), Positives = 36/87 (40%), Gaps = 27/87 (31%)
Query: 23 AAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLAL 82
A ++ LCG LV+ L VC RGF+++ + R
Sbjct: 1 AYRPSETLCGGELVDTLQFVCDGRGFYFSRPSSR-------------------------- 34
Query: 83 EGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 35 -INRRSRGIVEECCFRSCDLALLETYC 60
>gi|115169|sp|P26728|BXA5_BOMMO BOMBYXIN A-5 PRECURSOR (BBX-A5) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|102892|pir||JQ0817 bombyxin A-5 - silkworm
gi|2133585|pir||S72662 bombyxin A-5 precursor - silkworm
gi|217214|dbj|BAA00666.1| (D00770) bombyxin A-5 precursor [Bombyx mori]
Length = 92
Score = 73.8 bits (180), Expect = 3e-13
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M+LL +AL+ + CG HL L +C E G
Sbjct: 1 MKLLLAIALMLTTVMWASTQQPQTVHTYCGHHLARTLADLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + +RGIV++CC CS+ L +YC
Sbjct: 46 VDKRSDAQFASYGSAWLMPYSEGRDQRGIVDECCLRPCSVDVLLSYC 92
>gi|208431|gb|AAA72202.1| (J03739) insulin-like growth factor [synthetic construct]
Length = 70
Score = 73.4 bits (179), Expect = 3e-13
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
Q LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 2 PQALCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|3158368|gb|AAC17496.1| (AF033804) insulin-like growth factor II [Oreochromis mossambicus]
Length = 215
Score = 73.4 bits (179), Expect = 3e-13
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 27/109 (24%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M+ L L L+ + A+A + L G LV+AL VC +R F+++ T R
Sbjct: 29 MSSTNPALLFALALTLYLMEMASA---ETLFGGKLVDALQFVCEDRSFYFSRPTSRGNNR 85
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q RGIVE+C C L LE YC
Sbjct: 86 RP------------------------QTRGIVEECLFCSCDLNLLEQYC 110
>gi|115167|sp|P26726|BXA3_BOMMO BOMBYXIN A-3 PRECURSOR (BBX-A3) (4K-PROTHORACICOTROPIC HORMONE)
(4K-PTTH)
gi|69356|pir||IPMTA3 bombyxin A-3 precursor - silkworm
gi|155967|gb|AAA27827.1| (M26069) bombyxin A-3 [Bombyx mori]
Length = 92
Score = 73.4 bits (179), Expect = 3e-13
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 17/107 (15%)
Query: 5 MRLLPLLALLA--LWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQ 62
M++L +AL+ + CG HL L +C E G
Sbjct: 1 MKILLAIALMLSTVMWVSTQQPQGVHTYCGRHLARTLANLCWEAG--------------- 45
Query: 63 VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
V + GS + KRGIV++CC CS+ L +YC
Sbjct: 46 VDKRSDAQYVSYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC 92
>gi|1103534|emb|CAA92276.1| (Z68151) IGF2 [Bos taurus]
Length = 72
Score = 73.4 bits (179), Expect = 3e-13
Identities = 26/88 (29%), Positives = 37/88 (41%), Gaps = 27/88 (30%)
Query: 22 AAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLA 81
AA ++ LCG LV+ L VCG+ F+++ + R
Sbjct: 2 AAYRPSETLCGGELVDTLQFVCGDPPFYFSRPSSR------------------------- 36
Query: 82 LEGSLQKRGIVEQCCTSICSLYQLENYC 109
+ + RGIVE+CC C L LE YC
Sbjct: 37 --INRRSRGIVEECCFRSCDLALLETYC 62
>gi|208433|gb|AAA72203.1| (J03740) insulin-like growth factor [synthetic construct]
Length = 70
Score = 73.4 bits (179), Expect = 4e-13
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
Q LCG+ LV+ALYLVCG+RGF++ T + + Q
Sbjct: 2 PQALCGAELVDALYLVCGDRGFYFNKPTGYGSSSRRAPQ--------------------- 40
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 41 --TGIVDECCFRSCDLRRLEMYC 61
>gi|461662|sp|P33721|BXB1_SAMCY BOMBYXIN B-1 HOMOLOG PRECURSOR
gi|102957|pir||JQ0903 bombyxin B-1 homolog - ailanthus silkmoth
gi|217382|dbj|BAA03020.1| (D13923) Samia bombyxin homolog B-1 [Samia cynthia]
Length = 91
Score = 73.4 bits (179), Expect = 4e-13
Identities = 25/105 (23%), Positives = 42/105 (39%), Gaps = 14/105 (13%)
Query: 5 MRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVG 64
M++ + ++ +A + CG L + L +C E E
Sbjct: 1 MKVSMFVVIVLCMVAASSAGRGARRYCGRVLADTLAYLC---------PEMEEVEKRSGA 51
Query: 65 QVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q G P + EG+ KRG+V++CC + C+L L +YC
Sbjct: 52 QYARYGWQS-----PESREGARGKRGVVDECCYNSCTLDVLLSYC 91
>gi|69335|pir||INCD insulin - cod (Gadus sp.)
Length = 51
Score = 72.7 bits (177), Expect = 6e-13
Identities = 35/85 (41%), Positives = 41/85 (48%), Gaps = 36/85 (42%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
QHLCGSHLV+ALYLVCG+RGFFY PK
Sbjct: 3 PPQHLCGSHLVDALYLVCGDRGFFYNPK-------------------------------- 30
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIV+QCC C ++ L+NYCN
Sbjct: 31 ----GIVDQCCHRPCDIFDLQNYCN 51
>gi|8569480|pdb|3LRI|A Chain A, Solution Structure And Backbone Dynamics Of Human Long-
[arg3]insulin-Like Growth Factor 1
Length = 83
Score = 72.7 bits (177), Expect = 6e-13
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 23/83 (27%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
+ LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 15 PRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRACQ--------------------- 53
Query: 87 QKRGIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 54 --TGIVDECCFRSCDLRRLEMYC 74
>gi|227566|prf||1707201A insulin-like growth factor 1 [Sus scrofa domestica]
Length = 70
Score = 72.7 bits (177), Expect = 6e-13
Identities = 26/80 (32%), Positives = 36/80 (44%), Gaps = 23/80 (28%)
Query: 30 LCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKR 89
LCG+ LV+AL VCG+RGF++ T + + Q
Sbjct: 5 LCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-----------------------T 41
Query: 90 GIVEQCCTSICSLYQLENYC 109
GIV++CC C L +LE YC
Sbjct: 42 GIVDECCFRSCDLRRLEMYC 61
>gi|69339|pir||INTU2 insulin 2 - tuna
Length = 51
Score = 72.3 bits (176), Expect = 7e-13
Identities = 36/85 (42%), Positives = 42/85 (49%), Gaps = 36/85 (42%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
QHLCGSHLV+ALYLVCG+RGFFY PK
Sbjct: 3 PPQHLCGSHLVDALYLVCGDRGFFYNPK-------------------------------- 30
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC C+++ L+NYCN
Sbjct: 31 ----GIVEQCCHKPCNIFDLQNYCN 51
>gi|12644159|sp|P21808|BXE1_BOMMO BOMBYXIN E-1 PRECURSOR (BBX-E1) (BOMBYXIN IV)
(4K-PROTHORACICOTROPIC HORMONE IV) (4K-PTTH-IV)
gi|2388538|dbj|BAA22159.1| (D78138) prepro-bombyxin E1 [Bombyx mori]
Length = 98
Score = 72.3 bits (176), Expect = 7e-13
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 11/104 (10%)
Query: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66
+ +L L A V H CG HL L +C + E +
Sbjct: 5 VFLVLLLTGFLCIAAQEANVAHHYCGRHLANTLADLCWDT----------SVEKRSESSL 54
Query: 67 ELGGGPGAGSLQPLALE-GSLQKRGIVEQCCTSICSLYQLENYC 109
G L +++KRG+V++CC C+L L YC
Sbjct: 55 ASYSSRGWPWLPTPNFNKRAIKKRGVVDECCIQPCTLDVLATYC 98
>gi|4558198|pdb|1ZEI|A Chain A, Cross-Linked B28 Asp Insulin
gi|4558199|pdb|1ZEI|B Chain B, Cross-Linked B28 Asp Insulin
gi|4558200|pdb|1ZEI|C Chain C, Cross-Linked B28 Asp Insulin
gi|4558201|pdb|1ZEI|D Chain D, Cross-Linked B28 Asp Insulin
gi|4558202|pdb|1ZEI|E Chain E, Cross-Linked B28 Asp Insulin
gi|4558203|pdb|1ZEI|F Chain F, Cross-Linked B28 Asp Insulin
Length = 53
Score = 71.9 bits (175), Expect = 9e-13
Identities = 49/86 (56%), Positives = 50/86 (57%), Gaps = 33/86 (38%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYT K
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTDKA------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
+GIVEQCCTSICSLYQLENYCN
Sbjct: 31 ---AKGIVEQCCTSICSLYQLENYCN 53
>gi|69307|pir||INEL insulin - elephant
Length = 51
Score = 71.9 bits (175), Expect = 1e-12
Identities = 49/86 (56%), Positives = 50/86 (57%), Gaps = 35/86 (40%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKT------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCCT +CSLYQLENYCN
Sbjct: 31 -----GIVEQCCTGVCSLYQLENYCN 51
>gi|69316|pir||INHY insulin - hamster
Length = 51
Score = 71.9 bits (175), Expect = 1e-12
Identities = 49/86 (56%), Positives = 51/86 (58%), Gaps = 35/86 (40%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK+
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKS------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIV+QCCTSICSLYQLENYCN
Sbjct: 31 -----GIVDQCCTSICSLYQLENYCN 51
>gi|69303|pir||INWHP insulin - sperm whale
gi|69304|pir||INWHF insulin - finback whale (tentative sequence)
Length = 51
Score = 71.9 bits (175), Expect = 1e-12
Identities = 50/86 (58%), Positives = 50/86 (58%), Gaps = 35/86 (40%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPKA------------------------------ 30
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCCTSICSLYQLENYCN
Sbjct: 31 -----GIVEQCCTSICSLYQLENYCN 51
>gi|69347|pir||INAFP insulin - allmouth goosefish
Length = 51
Score = 71.5 bits (174), Expect = 1e-12
Identities = 36/85 (42%), Positives = 42/85 (49%), Gaps = 36/85 (42%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
QHLCGSHLV+ALYLVCG+RGFFY PK
Sbjct: 3 PAQHLCGSHLVDALYLVCGDRGFFYNPK-------------------------------- 30
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC C+++ L+NYCN
Sbjct: 31 ----GIVEQCCHRPCNIFDLQNYCN 51
>gi|461663|sp|P33722|BXB2_SAMCY BOMBYXIN B-2 HOMOLOG PRECURSOR
gi|102958|pir||JQ0905 bombyxin B-2 homolog - ailanthus silkmoth
gi|217385|dbj|BAA03022.1| (D13924) Samia bombyxin homolog B-2 [Samia cynthia]
Length = 91
Score = 71.5 bits (174), Expect = 1e-12
Identities = 28/109 (25%), Positives = 47/109 (42%), Gaps = 18/109 (16%)
Query: 1 MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAED 60
M + M ++ +L ++A+ +A + CG L + L +C E E
Sbjct: 1 MKVSMFVMIVLCMVAV----SSAGRGARRYCGRVLADTLAYLC---------PEMEEVEK 47
Query: 61 LQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
Q G P + EG+ KRG+V++CC + C+L L +YC
Sbjct: 48 RSGAQYARYGWQ-----LPESREGARGKRGVVDECCYNSCTLDVLLSYC 91
>gi|69317|pir||INMSSP insulin - Egyptian spiny mouse (tentative sequence)
Length = 51
Score = 71.5 bits (174), Expect = 1e-12
Identities = 46/83 (55%), Positives = 48/83 (57%), Gaps = 35/83 (42%)
Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 87
QHLCGSHLVEALYLVCGERGFFYTPK+
Sbjct: 4 QHLCGSHLVEALYLVCGERGFFYTPKS--------------------------------- 30
Query: 88 KRGIVEQCCTSICSLYQLENYCN 110
GIV+QCCTSICSLYQLENYCN
Sbjct: 31 --GIVDQCCTSICSLYQLENYCN 51
>gi|69345|pir||INGXA insulin - alligator gar
Length = 52
Score = 71.5 bits (174), Expect = 1e-12
Identities = 40/85 (47%), Positives = 44/85 (51%), Gaps = 34/85 (40%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
NQHLCGSHLVEALYLVCGE+GFFY P
Sbjct: 2 ANQHLCGSHLVEALYLVCGEKGFFYNP--------------------------------- 28
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
K GIVEQCC C++Y+LENYCN
Sbjct: 29 -NKVGIVEQCCHKPCTIYELENYCN 52
>gi|165928|gb|AAA31544.1| (M89787) insulin-like growth factor I [Ovis aries]
Length = 81
Score = 71.5 bits (174), Expect = 1e-12
Identities = 25/79 (31%), Positives = 34/79 (42%), Gaps = 23/79 (29%)
Query: 31 CGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRG 90
CG LV+AL VCG+RGF++ T + + Q G
Sbjct: 1 CGVELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQ-----------------------TG 37
Query: 91 IVEQCCTSICSLYQLENYC 109
IV++CC C L +LE YC
Sbjct: 38 IVDECCFRSCDLRRLEMYC 56
>gi|69343|pir||INFLE insulin - European flounder
Length = 51
Score = 71.1 bits (173), Expect = 2e-12
Identities = 37/85 (43%), Positives = 43/85 (50%), Gaps = 36/85 (42%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
QHLCG+HLV+ALYLVCGERGFFYTPK
Sbjct: 3 PPQHLCGAHLVDALYLVCGERGFFYTPK-------------------------------- 30
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC C+++ L+NYCN
Sbjct: 31 ----GIVEQCCHKPCNIFDLQNYCN 51
>gi|69338|pir||INFIS insulin - shorthorn sculpin
Length = 50
Score = 71.1 bits (173), Expect = 2e-12
Identities = 37/84 (44%), Positives = 41/84 (48%), Gaps = 36/84 (42%)
Query: 27 NQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSL 86
QHLCGSHLV+ALYLVCG+RGFFY PK
Sbjct: 3 PQHLCGSHLVDALYLVCGDRGFFYNPK--------------------------------- 29
Query: 87 QKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC C++ LENYCN
Sbjct: 30 ---GIVEQCCHRPCNIRVLENYCN 50
>gi|7532878|gb|AAF63265.1| (AF216775) insulin-like growth factor 1; igf-1 [Carassius auratus]
Length = 62
Score = 71.1 bits (173), Expect = 2e-12
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 23/82 (28%)
Query: 28 QHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 87
+ LCG+ LV+ L VCG+RGF+++ T
Sbjct: 2 ETLCGAELVDTLQFVCGDRGFYFSKPTGSGPSSR-----------------------RSH 38
Query: 88 KRGIVEQCCTSICSLYQLENYC 109
RGIV++CC C L +LE YC
Sbjct: 39 NRGIVDECCFQSCELRRLEMYC 60
>gi|69336|pir||INTF1 insulin 1 - toadfish (tentative sequence)
Length = 51
Score = 71.1 bits (173), Expect = 2e-12
Identities = 35/85 (41%), Positives = 41/85 (48%), Gaps = 36/85 (42%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
QHLCGSHLV+ALYLVCG+RGFFY PK
Sbjct: 3 PPQHLCGSHLVDALYLVCGDRGFFYNPK-------------------------------- 30
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC C ++ L++YCN
Sbjct: 31 ----GIVEQCCHRPCDIFDLQSYCN 51
>gi|494923|pdb|6INS|E Chain E, Insulin (Peptide-Linked, 29b - 1a, Des-30b)
gi|494924|pdb|6INS|F Chain F, Insulin (Peptide-Linked, 29b - 1a, Des-30b)
Length = 50
Score = 70.7 bits (172), Expect = 2e-12
Identities = 50/86 (58%), Positives = 50/86 (58%), Gaps = 36/86 (41%)
Query: 25 FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEG 84
FVNQHLCGSHLVEALYLVCGERGFFYTPK
Sbjct: 1 FVNQHLCGSHLVEALYLVCGERGFFYTPK------------------------------- 29
Query: 85 SLQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCCTSICSLYQLENYCN
Sbjct: 30 -----GIVEQCCTSICSLYQLENYCN 50
>gi|69326|pir||INTK insulin - turkey (tentative sequence)
gi|69327|pir||INOS insulin - ostrich
gi|280696|pir||A60414 insulin - slider turtle
gi|477645|pir||A61129 insulin - black-bellied slider
Length = 51
Score = 70.7 bits (172), Expect = 2e-12
Identities = 44/85 (51%), Positives = 46/85 (53%), Gaps = 35/85 (41%)
Query: 26 VNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGS 85
NQHLCGSHLVEALYLVCGERGFFY+PK
Sbjct: 2 ANQHLCGSHLVEALYLVCGERGFFYSPKA------------------------------- 30
Query: 86 LQKRGIVEQCCTSICSLYQLENYCN 110
GIVEQCC + CSLYQLENYCN
Sbjct: 31 ----GIVEQCCHNTCSLYQLENYCN 51
Database: nr
Posted date: Oct 1, 2001 12:31 AM
Number of letters in database: 242,984,850
Number of sequences in database: 764,431
Lambda K H
0.317 0.149 0.440
Gapped
Lambda K H
0.267 0.0455 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,199,716
Number of Sequences: 764431
Number of extensions: 1498086
Number of successful extensions: 9787
Number of sequences better than 10.0: 599
Number of HSP's better than 10.0 without gapping: 563
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 8852
Number of HSP's gapped (non-prelim): 681
length of query: 110
length of database: 242,984,850
effective HSP length: 86
effective length of query: 24
effective length of database: 177,243,784
effective search space: 4253850816
effective search space used: 4253850816
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 63 (28.7 bits)
