TP bioinformatique



Exercise : Align large genomic sequences with PipMaker


Objective: compare the human and mouse IL2R-alpha locus to identify conserved regions .
 

Step 1: Identify repeated sequences with RepeatMasker (return format: html) (human repeats)

Step 2: Prepare annotation files  (exons, other features to be colored)

Step 3: Align with PipMaker: use "advanced PipMaker" (***)


For review, see:

 


Ureta-Vidal A, Ettwiller L, Birney E. Related Articles, Links
Abstract Comparative genomics: genome-wide analysis in metazoan eukaryotes.
Nat Rev Genet. 2003 Apr;4(4):251-62.