What's New in NRSub

Release 10.1 (December 1997)

• Complete genome is available.
• Total number of bases: 4,214,814.
• The only sequence is named BACSUCG, to follow the convention used in the NRBact database.
• Integration of cross-references to gene families from HOBACGEN, a database of homologous genes in bacteria, this under the /gene_family qualifier.
• Cross-references to Escherichia coli orthologous genes are no longer integrated in the features.
• Computed map positions with an accuracy in tenth of degree are given for all genes.

Release 9 (September 1996)

• Total number of bases: 1,983,150.
• Integration of data from SubtiList 12.

Release 8 (July 1996)

• Total number of bases: 1,910,443.
• Integration of data from SubtiList 11.
• Integration of cross-references to E.coli orthologous protein genes, this with a /note qualifier. Cross-references are made with SWISS-PROT.
• A Macintosh version of the database and of its retrieval system is now available.

Release 7 (April 1996)

• Total number of bases: 1,616,172.
• Integration of data from SubtiList 10.
• /xref qualifier replaced by /db_xref which is now the standard for EMBL/GenBank/DDBJ repository databases.

Release 6 (October 1995)

• Total number of bases: 1,483,324.
• Integration of data from SubtiList 8 and 9.

Release 5 (June 1995)

• Total number of bases: 1,380,098.
• Integration of data from SubtiList 7.
• Sequences are now named following their position on the chromosome.
• The DE field contains now not only the primary accession number of the sequences used to build the contigs but also those of the duplicates.
• Introduction of cross-references with bibliographic database MEDLINE.
• Introduction of an /alt_name qualifier for all the alternative gene names.
• /map replaces /genetic_map to ensure compatibility with SRS.
• All ORFs have their own name, based on the form yxzN.
• All non-168 sequences are removed from the distribution.

Release 4 (January 1995)

• Total number of bases: 1,251,557.
• Integration of data from SubtiList 6.
• Sequences are numbered following their position on the chromosome of the 168 strain. Sequences with the highest numbers are not mapped or have been sequenced in non-168 strains.
• All the sequences use now a name of the form BSCONTxxx. The form BSORIGxxx is no longer used.
• To retrieve the composite contigs, it is now necessary to use the keyword composite instead of contig.
• WWW access is provided.

Release 3 (December 1994)

• Total number of bases:1,248,008.
• Integration of data from SubtiList 5 and EMBL 39.
• Moving of the contig coordinates from /merge qualifier to DE field.
• Adding of the coordinates on the genetic map for all the genes in the /map qualifier.
• Moving of the cross-references from DR field to /xref qualifier.
• Systematic addition of all the cross-references to SWISS-PROT.
• Definition of accession numbers for all the genes (protein genes and structural RNA genes).
• It is possible to retrieve non-168 sequences using the keyword non-168 strain. Indication of the strain name is given in CC field.

Release 2 (October 1994)

• Total number of bases: 1,038,404.
• Integration of data from EMBL 38.
• Introduction of the contig coordinates in a /merge qualifier.
• Introduction of dedicated accession numbers on the form BSxxxx.
• Non-composite sequences now designed by a name of the form BSORIGxxx.
• Sequence names from the original EMBL database used to build the contigs are replaced by their accession numbers.
• Introduction of the keyword hypothetical protein for accessing directly all the ORFs.
• Systematic use of the gene names and products from SWISS-PROT instead of EMBL/GenBank/DDBJ.

Release 1 (July 1994)

• First release of NRSub, for internal use only.
• Total number of bases: 1,005,179.
• Building of the original contigs starting from EMBL 37.