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Transcriptomics & proteomics : Tools

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EST clustering and analysis

Name Description Link
made in France ADEL Analysis of Distribution of ESTs in cDNA Libraries ADEL online
made in France BLAST on Unigene Identification of an EST as a member of a Unigene cluster greatly enhanced the corresponding gene characterization
made in France Ensembl for SIGENAE Ensembl : Sigenae EST ContigBrowser (Bos taurus, Gallus gallus, Oncorhynchus mykiss, Sus scrofa, Oryctolagus cuniculus) Sigenae EST ContigBrowser
made in France EPA integrated system for EST collection Processing and semi-automatic Annotation EPA online
made in France EST analysis suite a bioinformatics suite to perform EST data analysis more information
made in France Significance of digital gene expression profiles statistical analysis of digital transcription profiles data homepage
made in France SNP detection This system permits the detection via two different strategies : SNP detection in EST databases, and SNP detection in sequences produced by direct DNA sequencing. webpage
TGI Clustering tools fast clustering of large EST datasets TGI Software Tools

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Proteomics

Name Description Link
made in France ASCQ_ME data mining program for the identification of proteins from mass spectrometry raw data homepage
made in France BlastSets New strategy for the representation and the integration of biomolecular knowledge at a cellular scale. webpage
made in France Gelprint generates an in silico 2D-gel from the theoretical pI (isoelectric point) and Mw (molecular weight) data for a set of proteins Gelprint online
made in France Glycoproteomics automatic interpretation of glycans and glycoproteins mass spectra description in Lille
made in France Pepline A tool for high throughput proteomics developped by the Helix team. Pepline’s webpage
made in France Predotar a neural-network-based prediction program capable of identifying ER signal peptides and mitochondrial or plastid transit peptides Predotar online

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Transcriptomics : clustering and analysis

Name Description Link
AMIADA an integrated computer program for organizing, exploring, visualizing, and analyzing microarray data homepage
made in France AnovArray SAS package relying on ANOVA (Analysis of Variance) and multiple hypothesis testing based on FDR (False Discovery Rate)
AQBC Adaptive quality-based clustering of gene expression profiles
Array File Maker generates input files for clustering, helps prepare colored figures and Venn diagrams, and can uncover aneuploidy in yeast microarray data. homepage
Autoclass Unsupervised classification software.
made in France BLAST on Unigene Identification of an EST as a member of a Unigene cluster greatly enhanced the corresponding gene characterization
BRB Array tool an integrated package for the visualization and statistical analysis of DNA microarray gene expression data using an Excel front end homepage
Cleaver facilities for visualization, classification, and clustering homepage
Clusfavor Cluster and Factor Analysis Using Varimax Orthogonal Rotation
ClusPackX Differential expression test, classification and visualisation of expression class profiles.
Cluster A short program for PCA and Hierarchical clustering
Cluster analysis Online software for unsupervised clustering online form
ClusterW Clustering with clustalW
D-chip a software package implementing model-based expression analysis of oligonucleotide arrays and several high-level analysis procedures homepage
Data processing of time course data A suite of Excel spreadsheet templates homepage
made in France Difftool Building and visualizing protein clusters
DNA Microarray Data Analysis Script
EPCLUST EBI’s clutering program
Expression Profiler cluster analysis, pattern discovery, pattern visualization, study and search Gene Ontology categories, ... homepage
fcluster a tool for fuzzy cluster analysis homepage
GeneCluster filter and preprocess data in a variety of ways, cluster expression profiles using the SOM algorithm, view the results. webpage
Genesight explore large data sets from multiple experimental groups using advanced normalization, visualization, and statistical decision support tools webpage
GeneViz Double Conjugated Clustering software list
GEPAS Gene Expression Pattern Analysis Suite homepage
made in France Identitag Tag-to-gene mapping for SAGE data
J-express multidimensional scaling, clustering, and visualisation homepage
MAANOVA a set of functions written in Matlab for the analysis of variance on microarray data webpage
made in France MADTools composed of a local data base (MADSTAR), data processing software (MADSCAN), comprehension support tool (MADSENSE) and an automatic analysis of sequences software
MAExplorer MicroArray Explorer
MeV Multi experiment Viewer
Normalise suite normalise individual arrays across the entire array or by subgrids, group individual arrays into a project and take specific projects and generate results plots homepage
SAM-software Supervised learning software for genomic expression data mining homepage
SMA R-package : Statistics for Microarray Analysis homepage
Snob uses the Minimum Message Length principle to do clustering Snob page
SOTA Self Organising Tree Algorithm online form
svmlight an implementation of Support Vector Machines which solves classification and regression problems homepage
Treeview Graphically browse results of clustering and other analyses from Cluster Eisen software
Xcluster A fast and efficient software for clustering Xcluster homepage

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Transcriptomics : visualization

Name Description Link
AGScan a micro-array image processing software AGScan’s webpage
Array File Maker generates input files for clustering, helps prepare colored figures and Venn diagrams, and can uncover aneuploidy in yeast microarray data. homepage
made in France ArrayPlot Normalization software, with some visualization tools homepage
BRB Array tool an integrated package for the visualization and statistical analysis of DNA microarray gene expression data using an Excel front end homepage
Clusfavor Cluster and Factor Analysis Using Varimax Orthogonal Rotation
ClusPackX Differential expression test, classification and visualisation of expression class profiles.
D-chip a software package implementing model-based expression analysis of oligonucleotide arrays and several high-level analysis procedures homepage
Expression Profiler cluster analysis, pattern discovery, pattern visualization, study and search Gene Ontology categories, ... homepage
Freeview viewing and optimizing gene expression dendrograms homepage
Genesight explore large data sets from multiple experimental groups using advanced normalization, visualization, and statistical decision support tools webpage
GEPAS Gene Expression Pattern Analysis Suite homepage
J-express multidimensional scaling, clustering, and visualisation homepage
MAExplorer MicroArray Explorer
Slcview create image files from .cdt and .gtr files en masse from a Unix command prompt homepage
SOMview Make Xcluster graphics webpage
SOTA Self Organising Tree Algorithm online form
TreeMapClusterView explore microarray data using a tree view webpage
Treeview Graphically browse results of clustering and other analyses from Cluster Eisen software

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Transcriptomics : normalization

Name Description Link
AMIADA an integrated computer program for organizing, exploring, visualizing, and analyzing microarray data homepage
made in France ArrayPlot Normalization software, with some visualization tools homepage
BRB Array tool an integrated package for the visualization and statistical analysis of DNA microarray gene expression data using an Excel front end homepage
D-chip a software package implementing model-based expression analysis of oligonucleotide arrays and several high-level analysis procedures homepage
DNA Microarray Data Analysis Script
Genesight explore large data sets from multiple experimental groups using advanced normalization, visualization, and statistical decision support tools webpage
GEPAS Gene Expression Pattern Analysis Suite homepage
MAANOVA a set of functions written in Matlab for the analysis of variance on microarray data webpage
MAExplorer MicroArray Explorer
MarC-V Microarray Calculation and Visualisation homepage
MIDAS Microarray Data Analysis System Microarray software suite TM4
Normalise suite normalise individual arrays across the entire array or by subgrids, group individual arrays into a project and take specific projects and generate results plots homepage
SMA R-package : Statistics for Microarray Analysis homepage
SNOMAD Standardization and NOrmalization of MicroArray Data online forms
tpWY t-statistics, p-values, and Westfall and Young step-down method homepage

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Transcriptomics : preprocessing

Name Description Link
AMIADA an integrated computer program for organizing, exploring, visualizing, and analyzing microarray data homepage
Array File Maker generates input files for clustering, helps prepare colored figures and Venn diagrams, and can uncover aneuploidy in yeast microarray data. homepage
Data processing of time course data A suite of Excel spreadsheet templates homepage
MeV Multi experiment Viewer
SAM-software Supervised learning software for genomic expression data mining homepage

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Transcriptomics : probe design

Name Description Link
made in France CAPS marker description after restriction profiles analysis
made in France Clone selection
made in France Degenerate primers design Degenerate primers based on a set of proteic sequences
made in France FindExpress internal primer design on a set of nucleotidic sequences
made in France Genofrag Primer design program in two steps, first primer selection then genome fragmentation
Interactive PCR Primer Design Part of GeneFischer package
made in France Microsatellites primers Microsatellite repeat search with Sputnik and primers design with Primer3
Oligo Heat Map an online tool to estimate and display hybridizations of oligonucleotides onto DNA sequences Use Oligo Heat Map
made in France Oligo search
Primo A primer design tool
made in France Roso A software to design optimized oligonucleotide probes (size over 25 nucleotides) for microarrays
made in France Spads design a GST (Gene-Specific Tag) and a specific primer set for its PCR amplification, on a genomic sequence, knowing the gene structure Spads webpage
made in France XXFrag help the biologist in the creation of Biochips by collecting some fragments coming from the pseudogenome required

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