Estimation functions and diagnostic tools for mean length-based total mortality estimators based on Gedamke and Hoenig (2006) <doi:10.1577/T05-153.1>.

Various utilities for the Multiplicative Multinomial distribution.

Gene Expression datasets for the 'MM2S' package. Contains normalized expression data for Human Medulloblastoma ('GSE37418') as well as Mouse Medulloblastoma models ('GSE36594'). Deena Gendoo et al. (2015) <doi:10.1016/j.ygeno.2015.05.002>.

The main function MMEst() performs (Restricted) Maximum Likelihood in a variance component mixed models using a Min-Max (MM) algorithm (Laporte, F., Charcosset, A. & Mary-Huard, T. (2022) <doi:10.1371/journal.pcbi.1009659>).

Used for general multiple mediation analysis. 
	The analysis method is described in Yu and Li (2022) (ISBN: 9780367365479) "Statistical Methods for Mediation, Confounding and Moderation Analysis Using R and SAS", published by Chapman and Hall/CRC; and Yu et al.(2017) <DOI:10.1016/j.sste.2017.02.001> "Exploring racial disparity in obesity: a mediation analysis considering geo-coded environmental factors", published on Spatial and Spatio-temporal Epidemiology, 21, 13-23.

Used for general multiple mediation analysis with big data sets.

Contains the data sets for the first and second editions of the textbook 
    "Mathematical Modeling and Applied Calculus" by Joel Kilty and Alex M. McAllister. 
    The first edition of the book was published by Oxford University Press in 2018 with 
    ISBN-13: 978-019882472. The second edition is expected to be published in January 
    2027.

The minorization-maximization (MM) algorithm is a powerful tool for maximizing nonconcave target function. However, for most existing MM algorithms, the surrogate function in the minorization step is constructed in a case-specific manner and requires manual programming. To address this limitation, we develop the R package MMAD, which systematically integrates the assembly--decomposition technology in the MM framework. This new package provides a comprehensive computational toolkit for one-stop inference of complex target functions, including function construction, evaluation, minorization and optimization via MM algorithm. By representing the target function through a hierarchical composition of assembly functions, we design a hierarchical algorithmic structure that supports both bottom-up operations (construction, evaluation) and top-down operation (minorization).