Generalization of the classification and regression tree (CART) model that partitions subjects into terminal nodes and tailors machine learning model to each terminal node.

Bayesian nonstationary, semiparametric nonlinear regression 
 and design by treed Gaussian processes (GPs) with jumps to the limiting 
 linear model (LLM).  Special cases also implemented include Bayesian 
 linear models, CART, treed linear models, stationary separable and 
 isotropic GPs, and GP single-index models.  Provides 1-d and 2-d plotting functions 
 (with projection and slice capabilities) and tree drawing, designed for 
 visualization of tgp-class output.  Sensitivity analysis and 
 multi-resolution models are supported. Sequential experimental 
 design and adaptive sampling functions are also provided, including ALM, 
 ALC, and expected improvement.  The latter supports derivative-free
 optimization of noisy black-box functions.  For details and tutorials, 
 see Gramacy (2007) <doi:10.18637/jss.v019.i09> and Gramacy & Taddy (2010) 
 <doi:10.18637/jss.v033.i06>.

Functions to compute and plot tracheidograms, as in De Soto et al. (2011) <doi:10.1139/x11-045>.

Rapid advancements in high-throughput gene sequencing
    technologies have resulted in genome-scale time-series datasets. 
    Uncovering the underlying temporal sequence of gene regulatory events 
    in the form of time-varying gene regulatory networks demands 
    accurate and computationally efficient algorithms. Such an
    algorithm is 'TGS'. It is proposed in Saptarshi Pyne, Alok Ranjan 
    Kumar, and Ashish Anand. Rapid reconstruction of time-varying 
    gene regulatory networks. IEEE/ACM Transactions on Computational 
    Biology and Bioinformatics, 17(1):278{291, Jan-Feb 2020. The TGS 
    algorithm is shown to consume only 29 minutes for a microarray 
    dataset with 4028 genes. This package provides an implementation 
    of the TGS algorithm and its variants.

Functions for implementing the targeted gold standard (GS) testing. You provide the true disease or treatment failure status and the risk score, tell 'TGST' the availability of GS tests and which method to use, and it returns the optimal tripartite rules. Please refer to Liu et al. (2013) <doi:10.1080/01621459.2013.810149> for more details.