User-friendly Shiny apps for designing and evaluating phase I cancer clinical trials, with the aim to estimate the maximum tolerated dose (MTD) of a novel drug, using a Bayesian decision procedure based on logistic regression.

Function ModEstM() is the only one of this package, it estimates the modes of an empirical univariate distribution. It relies on the stats::density() function, even for input control. Due to very good performance of the density estimation, computation time is not an issue. The multiple modes are handled using dplyr::group_by(). For conditions and rates of convergences, see Eddy (1980) <doi:10.1214/aos/1176345080>.

Compute important quantities when we consider stochastic systems that are observed continuously. 
             Such as, Cost model, Limiting distribution, Transition matrix, Transition distribution and Occupancy matrix. 
             The methods are described, for example, Ross S. (2014), Introduction to Probability Models. Eleven Edition. Academic Press.

Analyses species distribution models and evaluates their performance. It includes functions for variation partitioning, extracting variable importance, computing several metrics of model discrimination and calibration performance, optimizing prediction thresholds based on a number of criteria, performing multivariate environmental similarity surface (MESS) analysis, and displaying various analytical plots. Initially described in Barbosa et al. (2013) <doi:10.1111/ddi.12100>.

This is a shiny module that presents a file picker user interface to get an Excel file name, and reads the Excel sheets using 'readxl' package and returns the resulting sheet(s) as a vector and data in dataframe(s).

Generation of synthetic data from a real dataset using the combination of rank normal inverse transformation with the calculation of correlation matrix <doi:10.1055/a-2048-7692>. Completely artificial data may be generated through the use of Generalized Lambda Distribution and Generalized Poisson Distribution <doi:10.1201/9781420038040>. Quantitative, binary, ordinal categorical, and survival data may be simulated. Functionalities are offered to generate synthetic data sets according to user's needs.