Designed to ease the application and comparison of multiple
    hypothesis testing procedures for FWER, gFWER, FDR and FDX. Methods are 
    standardized and usable by the accompanying 'mutossGUI'.

Provides a graphical user interface for the MuToss Project.

Cancer cells accumulate DNA mutations as result of DNA damage and DNA repair processes. This computational framework is aimed at deciphering DNA mutational signatures operating in cancer. The framework includes modules that support raw data import and processing, mutational signature extraction, and results interpretation and visualization. The framework accepts widely used file formats storing information about DNA variants, such as Variant Call Format files. The framework performs Non-Negative Matrix Factorization to extract mutational signatures explaining the observed set of DNA mutations. Bootstrapping is performed as part of the analysis. The framework supports parallelization and is optimized for use on multi-core systems. The software was described by Fantini D et al (2020) <doi:10.1038/s41598-020-75062-0> and is based on a custom R-based implementation of the original MATLAB WTSI framework by Alexandrov LB et al (2013) <doi:10.1016/j.celrep.2012.12.008>.

Measure quality of your tests.
    'muttest' introduces small changes (mutations) to your code
    and runs your tests to check if they catch the changes.
    If they do, your tests are good.
    If not, your assertions are not specific enough.
    'muttest' gives you percent score of how often your tests catch the changes.

The Mutual Information Index (M) introduced to social science literature by
    Theil and Finizza (1971) <doi:10.1080/0022250X.1971.9989795> is a multigroup
    segregation measure that is highly decomposable and that according to Frankel
    and Volij (2011) <doi:10.1016/j.jet.2010.10.008> and Mora and Ruiz-Castillo
    (2011) <doi:10.1111/j.1467-9531.2011.01237.x> satisfies the Strong Unit
    Decomposability and Strong Group Decomposability properties. This package allows
    computing and decomposing the total index value into its "between" and
    "within" terms. These last terms can also be decomposed into their
    contributions, either by group or unit characteristics. The factors that produce
    each "within" term can also be displayed at the user's request. The results can
    be computed considering a variable or sets of variables that define separate
    clusters.