The TWN-list (Taxa Waterbeheer Nederland) is the Dutch standard for naming 
    taxons in Dutch Watermanagement. This package makes it easier to use the 
    TWN-list for ecological analyses. It  consists of two parts. First it makes the 
    TWN-list itself available in R. Second, it has a few functions that make it 
    easy to perform some basic and often recurring tasks for checking and consulting
    taxonomic data from the TWN-list.

Comprehensive functions to calculate sample size and power for 
    clinical trials with two co-primary endpoints. The package supports five 
    endpoint combinations: two continuous endpoints (Sozu et al. 2011 
    <doi:10.1080/10543406.2011.551329>), two binary endpoints using asymptotic 
    methods (Sozu et al. 2010 <doi:10.1002/sim.3972>) and exact methods (Homma 
    and Yoshida 2025 <doi:10.1177/09622802251368697>), mixed continuous and 
    binary endpoints (Sozu et al. 2012 <doi:10.1002/bimj.201100221>), and mixed 
    count and continuous endpoints (Homma and Yoshida 2024 
    <doi:10.1002/pst.2337>). All methods appropriately account for correlation 
    between endpoints and provide both sample size and power calculation 
    capabilities.

Provides a calculator for the two-dimensional clinical Disease Activity 
    index for Psoriatic Arthritis (TwoDcDAPSA), a principal component-derived measure 
    that complements the conventional clinical DAPSA score. The TwoDcDAPSA captures 
    residual variation in patient-reported outcomes (pain and patient global assessment) 
    and joint counts (swollen and tender) after adjusting for standardized cDAPSA using 
    natural spline coefficients derived from published models. Residuals are 
    standardized and combined with fixed principal component loadings to yield a 
    continuous PROs-Joint Contrast (PJC) score and quartile groupings. The package 
    applies pre-specified coefficients and loadings to new datasets but does not 
    estimate spline models or principal components itself.