Compute effect sizes and their sampling variances from factorial experimental designs. The package supports calculation of simple effects, overall effects, and interaction effects for use in factorial meta-analyses. See Gurevitch et al. (2000) <doi:10.1086/303337>, Morris et al. (2007) <doi:10.1890/06-0442>, Lajeunesse (2011) <doi:10.1890/11-0423.1> and Macartney et al. (2022) <doi:10.1016/j.neubiorev.2022.104554>.

It can be used to create/encode molecular "license-plates" from sequences and to also decode the "license-plates" back to sequences.  While initially created for transfer RNA-derived small fragments (tRFs), this tool can be used for any genomic sequences including but not limited to: tRFs, microRNAs, etc. The detailed information can reference to Pliatsika V, Loher P, Telonis AG, Rigoutsos I (2016) <doi:10.1093/bioinformatics/btw194>. It can also be used to annotate tRFs. The detailed information can reference to Loher P, Telonis AG, Rigoutsos I (2017) <doi:10.1038/srep41184>.

Provides an extension to the 'lolog' package by introducing the minTriadicClosure() statistic to capture higher-order interactions among triplets of nodes. This function facilitates improved modelling of group formations and 'triadic' closure in networks. A smoothing parameter has been incorporated to avoid numerical errors.

Port the type guesser from 'readr' (so-called 'readr' first edition parsing engine, now superseded by 'vroom').

A toolkit for genomic selection in animal breeding with
    emphasis on multi-breed and multi-trait nested grouping operations.
    Streamlines iterative analysis workflows when working with 'ASReml-R'
    package.  Includes utility functions for phenotypic data processing
    commonly used by animal breeders.

An implementation of the iterative proportional fitting (IPFP), 
    maximum likelihood, minimum chi-square and weighted least squares procedures
    for updating a N-dimensional array with respect to given target marginal 
    distributions (which, in turn can be multidimensional). The package also
    provides an application of the IPFP to simulate multivariate Bernoulli
    distributions.