Derives the most frequent hierarchies along with their probability of occurrence. One can also define complex hierarchy criteria and calculate their probability. Methodology based on Papakonstantinou et al. (2021) <DOI:10.21203/rs.3.rs-858140/v1>.

Calculation and presentation of decision-invariant bias adjustment
    thresholds and intervals for Network Meta-Analysis, as described by 
    Phillippo et al. (2018) <doi:10.1111/rssa.12341>. These describe the 
    smallest changes to the data that would result in a change of decision.

Essentials for PK/PD (pharmacokinetics/pharmacodynamics) such as area under the curve, (geometric) coefficient of variation, and other calculations that are not part of base R. This is not a noncompartmental analysis (NCA) package.

Efficient tools for preparation, checking and post-processing of data in PK/PD (pharmacokinetics/pharmacodynamics) modeling, with focus on use of Nonmem, including consistency, traceability, and Nonmem compatibility of Data. Rigorously checks final Nonmem datasets. Implemented in 'data.table', but easily integrated with 'base' and 'tidyverse'.

Provides a framework to perform Non-negative Matrix
    Factorization (NMF). The package implements a set of already published algorithms
    and seeding methods, and provides a framework to test, develop and plug
    new/custom algorithms. Most of the built-in algorithms have been optimized
    in C++, and the main interface function provides an easy way of performing
    parallel computations on multicore machines.

Factorize binary matrices into rank-k components using the logistic function in the updating process. See e.g. Tomé et al (2015) <doi:10.1007/s11045-013-0240-9> .

Calculates the normalized mutual information (NMI) of two community structures in network analysis.

Contains functions useful for debugging, set operations on vectors,
    and 'UTC' date and time functionality. It adds a few vector manipulation 
    verbs to 'purrr' and 'dplyr' packages. It can also generate an R file to 
    install and update packages to simplify deployment into production. The 
    functions were developed at the data science firm 'Numeract LLC' and are 
    used in several packages and projects.