A minimal set of routines to calculate the Grantham distance
    <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to
    provide a proxy for the evolutionary distance between two amino acids
    based on three key chemical properties: composition, polarity and
    molecular volume. In turn, evolutionary distance is used as a proxy for
    the impact of missense mutations. The higher the distance, the more
    deleterious the substitution is expected to be.

Gene-Ranking Analysis of Pathway Expression (GRAPE) is a tool for
   summarizing the consensus behavior of biological pathways in the form of a
   template, and for quantifying the extent to which individual samples deviate
   from the template. GRAPE templates are based only on the relative rankings
   of the genes within the pathway and can be used for classification of tissue
   types or disease subtypes. GRAPE can be used to represent gene-expression
   samples as vectors of pathway scores, where each pathway score indicates the
   departure from a given collection of reference samples. The resulting pathway-
   space representation can be used as the feature set for various applications,
   including survival analysis and drug-response prediction. 
   Users of GRAPE should use the following citation:
   Klein MI, Stern DF, and Zhao H. GRAPE: A pathway template method to characterize 
   tissue-specific functionality from gene expression profiles. 
   BMC Bioinformatics, 18:317 (June 2017).

Turn arbitrary functions into binary operators.

Allows user to have graphical user interface to perform analysis of Agricultural experimental data. On using the functions in this package a Interactive User Interface will pop up. Apps Works by simple upload of files in CSV format.

Create interactive visualization charts to draw data in three dimensional graphs. The graphs can be included in Shiny apps and R markdown documents, or viewed from the R console and 'RStudio' Viewer. Based on the 'vis.js' Graph3d module and the 'htmlwidgets' R package.