A collection of robust statistical methods based on Wilcox' WRS functions. It implements robust t-tests (independent and dependent samples), robust ANOVA (including between-within subject designs), quantile ANOVA, robust correlation, robust mediation, and nonparametric ANCOVA models based on robust location measures.

Water resources system simulator is a tool for simulation and analysis of large-scale water resources systems. 'WRSS' proposes functions and methods for construction, simulation and analysis of primary storage and hydropower water resources features (e.g. reservoirs, aquifers, and etc.) based on Standard Operating Policy (SOP).

A collection of implementations of classical and
    novel algorithms for weighted sampling without replacement.
    Implementations include the algorithm of Efraimidis and Spirakis (2006)
    <doi:10.1016/j.ipl.2005.11.003> and Wong and Easton (1980)
    <doi:10.1137/0209009>.

An adaptation for estuaries (tidal waters) of weighted regression
    on time, discharge, and season to evaluate trends in water quality time series. 
    Please see Beck and Hagy (2015) <doi:10.1007/s10666-015-9452-8> for 
    details.

Top-Down mass spectrometry aims to identify entire proteins as well as their (post-translational) modifications or ions bound (eg Chen et al (2018) <doi:10.1021/acs.analchem.7b04747>). 
    The pattern of internal fragments (Haverland et al (2017) <doi:10.1007/s13361-017-1635-x>) may reveal important information about the original structure of the proteins studied 
    (Skinner et al (2018) <doi:10.1038/nchembio.2515> and Li et al (2018) <doi:10.1038/nchem.2908>). 
    However, the number of possible internal fragments gets huge with longer proteins and subsequent identification of internal fragments remains challenging, 
    in particular since the the accuracy of measurements with current mass spectrometers represents a limiting factor.   
    This package attempts to deal with the complexity of internal fragments and allows identification of terminal and internal fragments from deconvoluted mass-spectrometry data.