Facilitates the performance of several analyses, including simple and sequential path coefficient analysis, correlation estimate, drawing correlogram, Heatmap, and path diagram. When working with raw data, that includes one or more dependent variables along with one or more independent variables are available, the path coefficient analysis can be conducted. It allows for testing direct effects, which can be a vital indicator in path coefficient analysis. The process of preparing the dataset rule is explained in detail in the vignette file "Path.Analysis_manual.Rmd". You can find this in the folders labelled "data" and "~/inst/extdata". Also see: 1)the 'lavaan', 2)a sample of sequential path analysis in 'metan' suggested by Olivoto and Lúcio (2020) <doi:10.1111/2041-210X.13384>, 3)the simple 'PATHSAS' macro written in 'SAS' by Cramer et al. (1999) <doi:10.1093/jhered/90.1.260>, and 4)the semPlot() function of 'OpenMx' as initial tools for conducting path coefficient analyses and SEM (Structural Equation Modeling). To gain a comprehensive understanding of path coefficient analysis, both in theory and practice, see a 'Minitab' macro developed by Arminian, A. in the paper by Arminian et al. (2008) <doi:10.1080/15427520802043182>.

Provides path_chain class and functions, which facilitates loading and saving 
             directory structure in YAML configuration files via 'config' package. 
             The file structure you created during exploration can be transformed 
             into legible section in the config file, and then easily loaded for further usage.

Enrichment analysis enables researchers to uncover mechanisms 
    underlying a phenotype. However, conventional methods for enrichment 
    analysis do not take into account protein-protein interaction information, 
    resulting in incomplete conclusions. 'pathfindR' is a tool for enrichment 
    analysis utilizing active subnetworks. The main function identifies active 
    subnetworks in a protein-protein interaction network using a user-provided 
    list of genes and associated p values. It then performs enrichment analyses 
    on the identified subnetworks, identifying enriched terms (i.e. pathways or, 
    more broadly, gene sets) that possibly underlie the phenotype of interest.
    'pathfindR' also offers functionalities to cluster the enriched terms and 
    identify representative terms in each cluster, to score the enriched terms 
    per sample and to visualize analysis results. The enrichment, clustering and 
    other methods implemented in 'pathfindR' are described in detail in 
    Ulgen E, Ozisik O, Sezerman OU. 2019. 'pathfindR': An R Package for 
    Comprehensive Identification of Enriched Pathways in Omics Data Through 
    Active Subnetworks. Front. Genet. <doi:10.3389/fgene.2019.00858>.