API for fast data extraction for .hic files that provides programmatic access to the matrices. It doesn't store the pointer data for all the matrices, only the one queried, and currently we are only supporting matrices (not vectors).

This is a modification of 'HDoutliers' package. The 'HDoutliers' algorithm is a powerful 
    unsupervised algorithm for detecting anomalies in high-dimensional data, with a 
    strong theoretical foundation. However, it suffers from some limitations that 
    significantly hinder its performance level, under certain circumstances. This package 
    implements the algorithm proposed in Talagala, Hyndman and Smith-Miles (2019) 
    <arXiv:1908.04000>  for detecting anomalies in high-dimensional data
    that addresses these limitations of 'HDoutliers' algorithm. We define an anomaly as an observation that deviates markedly from the majority
    with a large distance gap. An approach based on extreme value theory is used 
    for the anomalous threshold calculation.

Performs receptor abundance estimation for single cell RNA-sequencing data using a supervised feature selection mechanism and a thresholded gene set scoring procedure. Seurat's normalization method is described in: Hao et al., (2021) <doi:10.1016/j.cell.2021.04.048>, Stuart et al., (2019) <doi:10.1016/j.cell.2019.05.031>, Butler et al., (2018) <doi:10.1038/nbt.4096> and Satija et al., (2015) <doi:10.1038/nbt.3192>. Method for reduced rank reconstruction and rank-k selection is detailed in: Javaid et al., (2022) <doi:10.1101/2022.10.08.511197>. Gene set scoring procedure is described in: Frost et al., (2020) <doi:10.1093/nar/gkaa582>. Clustering method is outlined in: Song et al., (2020) <doi:10.1093/bioinformatics/btaa613> and Wang et al., (2011) <doi:10.32614/RJ-2011-015>.

A framework for data stream modeling and associated data
    mining tasks such as clustering and classification. The development of
    this package was supported in part by NSF IIS-0948893, NSF CMMI
    1728612, and NIH R21HG005912. Hahsler et al (2017)
    <doi:10.18637/jss.v076.i14>.