InfluenceBorrowing: Adaptive Influence-Based Borrowing for Hybrid Control Trials
Implements the adaptive influence-based borrowing framework
proposed by Qinwei Yang, Jingyi Li, Peng Wu, and Shu Yang (2026+) in the paper
“Improving Treatment Effect Estimation in Trials through Adaptive Borrowing
of External Controls" <doi:10.48550/arXiv.2604.13973> for augmenting Randomized Controlled
Trials (RCTs) with External Control (EC) data. This package provides a
comprehensive workflow to: (1) quantify the comparability of external control
samples using influence scores approximated via the influence function of the
M-estimator; (2) construct candidate borrowing subsets and select the optimal
subset that minimizes the Mean Squared Error (MSE); and (3) calibrate systematic
differences in external outcomes using R-learner methods implemented via
Ordinary Least Squares or Kernel Ridge Regression.
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