ceas: Cellular Energetics Analysis Software
Analysis and visualization of cellular energetics data from Agilent Seahorse XF96. Cellular energetics is how cells make, use, and distribute units of energy (primarily ATP). Measuring real-time cellular energetics is essential to understanding a tissue or cell’s bioenergetic state and fuel dependencies. The Seahorse machine measures a cell’s or matrix’s oxygen consumption rate (OCR) – a proxy of oxidative phosphorylation – and extracellular acidification rate – a proxy of glycolysis. This package offers flexible and fast analysis and plotting capabilities for such data using the methods described by Mookerjee et al. (2017) <doi:10.1074/jbc.m116.774471>.
| Version: | 1.0.0 |
| Imports: | data.table, ggplot2, readxl, stats |
| Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
| Published: | 2024-05-07 |
| Author: | Rachel House 
[aut, cre],
James Eapen [aut],
Hui Shen [fnd],
Carrie Graveel
[fnd],
Matthew Steensma
[fnd],
Van Andel Institute [cph] |
| Maintainer: | Rachel House <rachel.house at vai.org> |
| BugReports: | https://github.com/jamespeapen/ceas/issues/ |
| License: | MIT + file LICENSE |
| URL: | https://jamespeapen.github.io/ceas/, https://github.com/jamespeapen/ceas/ |
| NeedsCompilation: | no |
| Materials: | README NEWS |
| CRAN checks: | ceas results |
Documentation:
| Reference manual: | ceas.pdf |
| Vignettes: |
ATP calculation Getting started with CEAS |
Downloads:
| Package source: | ceas_1.0.0.tar.gz |
| Windows binaries: | r-devel: ceas_1.0.0.zip, r-release: ceas_1.0.0.zip, r-oldrel: not available |
| macOS binaries: | r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): ceas_1.0.0.tgz, r-oldrel (x86_64): ceas_1.0.0.tgz |
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