(data stored in ACNUC941 zone)

SWISSPROT: Q9I8I6_TAKRU

ID   Q9I8I6_TAKRU            Unreviewed;       414 AA.
AC   Q9I8I6;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   30-AUG-2017, entry version 73.
DE   SubName: Full=Creatine kinase {ECO:0000313|EMBL:AAF78086.1};
DE            EC=2.7.3.2 {ECO:0000313|EMBL:AAF78086.1};
GN   Name=umtck {ECO:0000313|EMBL:AAF78086.1};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|EMBL:AAF78086.1};
RN   [1] {ECO:0000313|EMBL:AAF78086.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Fu R., Jiang M., Brenner S.;
RT   "Structure of the ubiquitous mitochondrial creatine kinase gene and
RT   its linkage to the protein disulfide isomerase ERp60 gene are
RT   conserved among teleost fish Takifugu rubripes, mouse and human.";
RL   Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU00843,
CC       ECO:0000256|RuleBase:RU000505, ECO:0000256|SAAS:SAAS00541973}.
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DR   EMBL; AF274502; AAF78086.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q9I8I6; -.
DR   PRIDE; Q9I8I6; -.
DR   eggNOG; KOG3581; Eukaryota.
DR   eggNOG; COG3869; LUCA.
DR   HOGENOM; HOG000232165; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004111; F:creatine kinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.135.10; -; 1.
DR   Gene3D; 3.30.590.10; -; 1.
DR   InterPro; IPR000749; ATP-guanido_PTrfase.
DR   InterPro; IPR022415; ATP-guanido_PTrfase_AS.
DR   InterPro; IPR022414; ATP-guanido_PTrfase_cat.
DR   InterPro; IPR022413; ATP-guanido_PTrfase_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   PANTHER; PTHR11547; PTHR11547; 1.
DR   Pfam; PF00217; ATP-gua_Ptrans; 1.
DR   Pfam; PF02807; ATP-gua_PtransN; 1.
DR   SUPFAM; SSF48034; SSF48034; 1.
DR   PROSITE; PS00112; PHOSPHAGEN_KINASE; 1.
DR   PROSITE; PS51510; PHOSPHAGEN_KINASE_C; 1.
DR   PROSITE; PS51509; PHOSPHAGEN_KINASE_N; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q9I8I6.
DR   SWISS-2DPAGE; Q9I8I6.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00843,
KW   ECO:0000256|SAAS:SAAS00424901};
KW   Kinase {ECO:0000256|PROSITE-ProRule:PRU00843,
KW   ECO:0000256|RuleBase:RU000505, ECO:0000256|SAAS:SAAS00424900,
KW   ECO:0000313|EMBL:AAF78086.1};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00843,
KW   ECO:0000256|SAAS:SAAS00424905};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU00843,
KW   ECO:0000256|RuleBase:RU000505, ECO:0000256|SAAS:SAAS00424898,
KW   ECO:0000313|EMBL:AAF78086.1}.
FT   DOMAIN       42    129       Phosphagen kinase N-terminal.
FT                                {ECO:0000259|PROSITE:PS51509}.
FT   DOMAIN      156    398       Phosphagen kinase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51510}.
FT   NP_BIND     159    163       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00843}.
FT   NP_BIND     323    327       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00843}.
FT   NP_BIND     351    356       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00843}.
FT   BINDING     222    222       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00843}.
FT   BINDING     267    267       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00843}.
SQ   SEQUENCE   414 AA;  46482 MW;  68591D087360A4A8 CRC64;
     MASSFSRVLT SRNIRILSLL GGSVTAGILL QRHHVGADGP TRRRYPASAE YPDLRKHNNC
     MASNLTPAIY AQLCDKTTPN GFTLDQAIQT GVDNPGHPFI KTVGLVAGDE ESYEVFAELM
     DPVIKERHNG YDPRGMKHPT DLDSSKVHSA QFDERYVLSS RVRTGRSIRG LSLPPACTRA
     ERREVERVVV DALAGLKGDL AGRYYSLTQM TEKEQQQLID DHFLFDKPVS PLLTCAGMAR
     DWPDARGIWH NNEKNFLVWI NEEDHTRVIS MEKGGNMKRV FDRFCRGLKE VERLIQEKGW
     EFMWNERLGY VLTCPSNLGT GLRAGVHVKL PLLSKDPRFS QILSSLRLQK RGTGGVDTAA
     VGGVFDISNL DRLGQSEVQL VQTVVDGVNY LIECEKMLER GHDIKVPPPR KQFK
//

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