(data stored in ACNUC941 zone)

HOGENOM: BOVIN7_85_PE3

ID   BOVIN7_85_PE3                        STANDARD;      PRT;   419 AA.
AC   BOVIN7_85_PE3; Q3ZBP1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Creatine kinase S-type, mitochondrial; EC=2.7.3 2;AltName:
DE   Full=Basic-type mitochondrial creatine kinase; Short=Mib-CK;AltName:
DE   Full=Sarcomeric mitochondrial creatine kinase; Short=S-MtCK;Flags:
DE   Precursor; (BOVIN7_85.PE3).
GN   Name=CKMT2;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN7_85.PE3.
CC       Bos taurus chromosome 7 Btau_4.0 partial sequence 81898233..82898232
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:KCRS_BOVIN
CC   -!- FUNCTION: Reversibly catalyzes the transfer of phosphate between
CC       ATP and various phosphogens (e.g. creatine phosphate). Creatine
CC       kinase isoenzymes play a central role in energy transduction in
CC       tissues with large, fluctuating energy demands, such as skeletal
CC       muscle, heart, brain and spermatozoa (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + creatine = ADP + phosphocreatine.
CC   -!- SUBUNIT: Exists as an octamer composed of four CKMT2 homodimers
CC       (By similarity).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral
CC       membrane protein; Intermembrane side (By similarity).
CC   -!- MISCELLANEOUS: Mitochondrial creatine kinase binds cardiolipin.
CC   -!- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase C-terminal domain.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase N-terminal domain.
CC   -!- GENE_FAMILY: HOG000232165 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000001003;ENSBTAT00000001330;ENSBTAP00000001330.
DR   EMBL; BC103190; - ;
DR   UniProtKB/Swiss-Prot; Q3ZBP1; -.
DR   EMBL; BC103190; AAI03191.1; -; mRNA.
DR   IPI; IPI00695493; -.
DR   RefSeq; NP_001029828.1; NM_001034656.1.
DR   UniGene; Bt.13980; -.
DR   ProteinModelPortal; Q3ZBP1; -.
DR   SMR; Q3ZBP1; 47-413.
DR   IntAct; Q3ZBP1; 1.
DR   STRING; Q3ZBP1; -.
DR   PRIDE; Q3ZBP1; -.
DR   GeneID; 538944; -.
DR   KEGG; bta:538944; -.
DR   CTD; 1160; -.
DR   eggNOG; maNOG11792; -.
DR   GeneTree; ENSGT00550000074561; -.
DR   InParanoid; Q3ZBP1; -.
DR   OrthoDB; EOG40VVPN; -.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; IEA:EC.
DR   InterPro; IPR000749; ATP-guanido_PTrfase.
DR   InterPro; IPR022415; ATP-guanido_PTrfase_AS.
DR   InterPro; IPR022414; ATP-guanido_PTrfase_cat.
DR   InterPro; IPR022413; ATP-guanido_PTrfase_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   Gene3D; G3DSA:1.10.135.10; ATP-gua_Ptrans; 1.
DR   Gene3D; G3DSA:3.30.590.10; ATP-gua_Ptrans; 1.
DR   PANTHER; PTHR11547; ATP-gua_Ptrans; 1.
DR   Pfam; PF00217; ATP-gua_Ptrans; 1.
DR   Pfam; PF02807; ATP-gua_PtransN; 1.
DR   SUPFAM; SSF48034; ATP-gua_Ptrans; 1.
DR   PROSITE; PS00112; PHOSPHAGEN_KINASE; 1.
DR   PROSITE; PS51510; PHOSPHAGEN_KINASE_C; 1.
DR   PROSITE; PS51509; PHOSPHAGEN_KINASE_N; 1.
DR   HOGENOMDNA; BOVIN7_85.PE3; -.
KW   ENSBTAG00000001003fold_1320000031; ENSBTAP00000001330fold_1320000031;
KW   BC103190;
KW   ATP-binding; Complete proteome; Kinase; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Nucleotide-binding; Reference proteome;
KW   Transferase; Transit peptide.
SQ   SEQUENCE   419 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MASTFSKLLT GRNASLLFAT LGTGALTTGY LLNKQNVCAA AREQHKLFPP SADYPDLRKH
     NNCMAECLTP AIYAKLRNKV TPSGYTLDQC IQTGVDNPGH PFIKTVGMVA GDEESYEVFA
     DLFDPVIKLR HNGYDPRVMK HPTDLDASKI TQGQFDERYV LSSRVRTGRS IRGLSLPPAC
     SRAERREVEN VAITALEGLK GDLAGRYYKL SEMTEQDQQR LIDDHFLFDK PVSPLLTCAG
     MARDWPDARG IWHNYDKTFL IWINEEDHTR VISMEKGGNM KRVFERFCRG LKEVERLIQE
     RGWEFMWNER LGYILTCPSN LGTGLRAGVH VRIPKLSKDP RFSKILENLR LQKRGTGGVD
     TAAVADVYDI SNIDRIGRSE VELVQIVIDG VNYLVDCEKK LERGQDIKVP PPLPQFGKK
//

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