(data stored in ACNUC941 zone)

HOGENOM: CHICKZ_PE832

ID   CHICKZ_PE832                         STANDARD;      PRT;   419 AA.
AC   CHICKZ_PE832; P11009;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Creatine kinase S-type, mitochondrial; EC=2.7.3 2;AltName:
DE   Full=Basic-type mitochondrial creatine kinase; Short=Mib-CK;AltName:
DE   Full=Sarcomeric mitochondrial creatine kinase; Short=S-MtCK;Flags:
DE   Precursor; (CHICKZ.PE832).
GN   Name=CKMT2;
OS   GALLUS GALLUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Sauropsida; Sauria; Archosauria;
OC   Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae;
OC   Galliformes; Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CHICKZ.PE832.
CC       Gallus gallus chromosome Z WASHUC2  sequence 1..74602320 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:KCRS_CHICK
CC   -!- FUNCTION: Reversibly catalyzes the transfer of phosphate between
CC       ATP and various phosphogens (e.g. creatine phosphate). Creatine
CC       kinase isoenzymes play a central role in energy transduction in
CC       tissues with large, fluctuating energy demands, such as skeletal
CC       muscle, heart, brain and spermatozoa.
CC   -!- CATALYTIC ACTIVITY: ATP + creatine = ADP + phosphocreatine.
CC   -!- SUBUNIT: Exists as an octamer composed of four MTCK homodimers.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral
CC       membrane protein; Intermembrane side.
CC   -!- TISSUE SPECIFICITY: Expressed in the leg muscle and heart.
CC   -!- MISCELLANEOUS: Mitochondrial creatine kinase binds cardiolipin.
CC   -!- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase C-terminal domain.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase N-terminal domain.
CC   -!- GENE_FAMILY: HOG000232165 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Gallus_gallus;ENSGALG00000015602;ENSGALT00000025156;ENSGALP00000025110.
DR   EMBL; M18866; - ;
DR   UniProtKB/Swiss-Prot; P11009; -.
DR   EMBL; M18866; AAA48688.1; -; mRNA.
DR   IPI; IPI00585452; -.
DR   PIR; A27708; A27708.
DR   RefSeq; NP_001161216.1; NM_001167744.1.
DR   UniGene; Gga.869; -.
DR   PDB; 1CRK; X-ray; 3.00 A; A/B/C/D=40-419.
DR   PDBsum; 1CRK; -.
DR   ProteinModelPortal; P11009; -.
DR   SMR; P11009; 40-419.
DR   STRING; P11009; -.
DR   GeneID; 396508; -.
DR   KEGG; gga:396508; -.
DR   CTD; 1160; -.
DR   eggNOG; veNOG04753; -.
DR   GeneTree; ENSGT00550000074561; -.
DR   InParanoid; P11009; -.
DR   OrthoDB; EOG40VVPN; -.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; IEA:EC.
DR   InterPro; IPR000749; ATP-guanido_PTrfase.
DR   InterPro; IPR022415; ATP-guanido_PTrfase_AS.
DR   InterPro; IPR022414; ATP-guanido_PTrfase_cat.
DR   InterPro; IPR022413; ATP-guanido_PTrfase_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   Gene3D; G3DSA:1.10.135.10; ATP-gua_Ptrans; 1.
DR   Gene3D; G3DSA:3.30.590.10; ATP-gua_Ptrans; 1.
DR   PANTHER; PTHR11547; ATP-gua_Ptrans; 1.
DR   Pfam; PF00217; ATP-gua_Ptrans; 1.
DR   Pfam; PF02807; ATP-gua_PtransN; 1.
DR   SUPFAM; SSF48034; ATP-gua_Ptrans; 1.
DR   PROSITE; PS00112; PHOSPHAGEN_KINASE; 1.
DR   PROSITE; PS51510; PHOSPHAGEN_KINASE_C; 1.
DR   PROSITE; PS51509; PHOSPHAGEN_KINASE_N; 1.
DR   HOGENOMDNA; CHICKZ.PE832; -.
KW   ENSGALG00000015602fold_1320000031; ENSGALP00000025110fold_1320000031;
KW   M18866;
KW   3D-structure; ATP-binding; Complete proteome;
KW   Direct protein sequencing; Kinase; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Nucleotide-binding; Reference proteome;
KW   Transferase; Transit peptide.
SQ   SEQUENCE   419 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAGTFGRLLA GRVTAALFAA AGTGVLTTGY LLNQQNVKAT VHEKRKLFPP SADYPDLRKH
     NNCMAECLTP AIYAKLRDKL TPNGYSLDQC IQTGVDNPGH PFIKTVGMVA GDEESYEVFA
     EIFDPVIKAR HNGYDPRTMK HHTDLDASKI THGQFDERYV LSSRVRTGRS IRGLSLPPAC
     SRAERREVEN VVVTALAGLK GDLSGKYYSL TNMSERDQQQ LIDDHFLFDK PVSPLLTCAG
     MARDWPDARG IWHNNDKTFL VWINEEDHTR VISMEKGGNM KRVFERFCRG LKEVERLIKE
     RGWEFMWNER LGYVLTCPSN LGTGLRAGVH VKLPRLSKDP RFPKILENLR LQKRGTGGVD
     TAAVADVYDI SNLDRMGRSE VELVQIVIDG VNYLVDCEKK LEKGQDIKVP PPLPQFGRK
//

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