(data stored in ACNUC941 zone)

HOGENOM: MOUSE12_PE1237

ID   MOUSE12_PE1237                       STANDARD;      PRT;   381 AA.
AC   MOUSE12_PE1237; Q04447; Q3KQP4; Q3TKI3; Q3U5P5; Q3UF71; Q9CXK6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Creatine kinase B-type; EC=2.7.3 2;AltName:
DE   Full=B-CK;AltName: Full=Creatine kinase B chain; (MOUSE12.PE1237).
GN   Name=Ckb; Synonyms=Ckbb;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE12.PE1237.
CC       Mus musculus chromosome 12 NCBIM37  sequence 1..121257530 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:KCRB_MOUSE
CC   -!- FUNCTION: Reversibly catalyzes the transfer of phosphate between
CC       ATP and various phosphogens (e.g. creatine phosphate). Creatine
CC       kinase isoenzymes play a central role in energy transduction in
CC       tissues with large, fluctuating energy demands, such as skeletal
CC       muscle, heart, brain and spermatozoa.
CC   -!- CATALYTIC ACTIVITY: ATP + creatine = ADP + phosphocreatine.
CC   -!- SUBUNIT: Dimer of identical or non-identical chains. With MM being
CC       the major form in skeletal muscle and myocardium, MB existing in
CC       myocardium, and BB existing in many tissues, especially brain.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase C-terminal domain.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase N-terminal domain.
CC   -!- GENE_FAMILY: HOG000232165 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000001270;ENSMUST00000001304;ENSMUSP00000001304.
DR   EMBL; AK002467; - ;
DR   EMBL; AK014299; - ;
DR   EMBL; AK148885; - ;
DR   EMBL; AK152388; - ;
DR   EMBL; AK153484; - ;
DR   EMBL; AK161990; - ;
DR   EMBL; AK166980; - ;
DR   EMBL; AK167034; - ;
DR   EMBL; BC015271; - ;
DR   EMBL; BC106109; - ;
DR   EMBL; L09069; - ;
DR   EMBL; M74149; - ;
DR   EMBL; X04591; - ;
DR   UniProtKB/Swiss-Prot; Q04447; Q3KQP4; Q3TKI3; Q3U5P5; Q3UF71; Q9CXK6; -.
DR   EMBL; M74149; AAA37462.1; -; Genomic_DNA.
DR   EMBL; L09069; AAA37455.1; -; Genomic_DNA.
DR   EMBL; AK002467; BAB22121.1; -; mRNA.
DR   EMBL; AK014299; BAB29254.1; -; mRNA.
DR   EMBL; AK148885; BAE28690.1; -; mRNA.
DR   EMBL; AK152388; BAE31176.1; -; mRNA.
DR   EMBL; AK153484; BAE32032.1; -; mRNA.
DR   EMBL; AK166980; BAE39162.1; -; mRNA.
DR   EMBL; AK161990; BAE36669.1; -; mRNA.
DR   EMBL; AK167034; BAE39205.1; -; mRNA.
DR   EMBL; BC015271; AAH15271.1; -; mRNA.
DR   EMBL; BC106109; AAI06110.2; -; mRNA.
DR   EMBL; X04591; CAA28259.1; -; mRNA.
DR   IPI; IPI00136703; -.
DR   PIR; A42078; A42078.
DR   RefSeq; NP_067248.1; NM_021273.4.
DR   UniGene; Mm.16831; -.
DR   ProteinModelPortal; Q04447; -.
DR   SMR; Q04447; 6-381.
DR   IntAct; Q04447; 2.
DR   STRING; Q04447; -.
DR   PhosphoSite; Q04447; -.
DR   REPRODUCTION-2DPAGE; Q04447; -.
DR   UCD-2DPAGE; Q04447; -.
DR   PRIDE; Q04447; -.
DR   Ensembl; ENSMUST00000001304; ENSMUSP00000001304; ENSMUSG00000001270.
DR   GeneID; 12709; -.
DR   KEGG; mmu:12709; -.
DR   UCSC; uc007pdn.2; mouse.
DR   CTD; 1152; -.
DR   MGI; MGI:88407; Ckb.
DR   eggNOG; roNOG15359; -.
DR   GeneTree; ENSGT00550000074561; -.
DR   InParanoid; Q04447; -.
DR   OMA; RGHEFMW; -.
DR   OrthoDB; EOG4R7V9X; -.
DR   NextBio; 281980; -.
DR   ArrayExpress; Q04447; -.
DR   Bgee; Q04447; -.
DR   CleanEx; MM_CKB; -.
DR   Genevestigator; Q04447; -.
DR   GermOnline; ENSMUSG00000001270; Mus musculus.
DR   GO; GO:0005739; C:mitochondrion; IDA:MGI.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; IEA:EC.
DR   InterPro; IPR000749; ATP-guanido_PTrfase.
DR   InterPro; IPR022415; ATP-guanido_PTrfase_AS.
DR   InterPro; IPR022414; ATP-guanido_PTrfase_cat.
DR   InterPro; IPR022413; ATP-guanido_PTrfase_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   Gene3D; G3DSA:1.10.135.10; ATP-gua_Ptrans; 1.
DR   Gene3D; G3DSA:3.30.590.10; ATP-gua_Ptrans; 1.
DR   PANTHER; PTHR11547; ATP-gua_Ptrans; 1.
DR   Pfam; PF00217; ATP-gua_Ptrans; 1.
DR   Pfam; PF02807; ATP-gua_PtransN; 1.
DR   SUPFAM; SSF48034; ATP-gua_Ptrans; 1.
DR   PROSITE; PS00112; PHOSPHAGEN_KINASE; 1.
DR   PROSITE; PS51510; PHOSPHAGEN_KINASE_C; 1.
DR   PROSITE; PS51509; PHOSPHAGEN_KINASE_N; 1.
DR   HOGENOMDNA; MOUSE12.PE1237; -.
KW   ENSMUSG000000012705old_1320000031; ENSMUSP000000013041old_1320000031;
KW   AK002467; AK014299; AK148885; AK152388; AK153484; AK161990; AK166980;
KW   BC015271; BC106109; L09069; M74149; X04591;
KW   ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing;
KW   Kinase; Nitration; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Transferase.
SQ   SEQUENCE   381 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPFSNSHNTQ KLRFPAEDEF PDLSSHNNHM AKVLTPELYA ELRAKCTPSG FTLDDAIQTG
     VDNPGHPYIM TVGAVAGDEE SYDVFKDLFD PIIEERHGGY QPSDEHKTDL NPDNLQGGDD
     LDPNYVLSSR VRTGRSIRGF CLPPHCSRGE RRAIEKLAVE ALSSLDGDLS GRYYALKSMT
     EAEQQQLIDD HFLFDKPVSP LLLASGMARD WPDARGIWHN DNKTFLVWIN EEDHLRVISM
     QKGGNMKEVF TRFCTGLTQI ETLFKSKNYE FMWNPHLGYI LTCPSNLGTG LRAGVHIKLP
     HLGKHEKFSE VLKRLRLQKR GTGGVDTAAV GGVFDVSNAD RLGFSEVELV QMVVDGVKLL
     IEMEQRLEQG QAIDDLMPAQ K
//

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