(data stored in ACNUC941 zone)

HOGENOM: MOUSE7_PE551

ID   MOUSE7_PE551                         STANDARD;      PRT;   381 AA.
AC   MOUSE7_PE551; P07310;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Creatine kinase M-type; EC=2.7.3 2;AltName: Full=Creatine
DE   kinase M chain;AltName: Full=M-CK; (MOUSE7.PE551).
GN   Name=Ckm; Synonyms=Ckmm;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE7.PE551.
CC       Mus musculus chromosome 7 NCBIM37  sequence 1..152524553 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:KCRM_MOUSE
CC   -!- FUNCTION: Reversibly catalyzes the transfer of phosphate between
CC       ATP and various phosphogens (e.g. creatine phosphate). Creatine
CC       kinase isoenzymes play a central role in energy transduction in
CC       tissues with large, fluctuating energy demands, such as skeletal
CC       muscle, heart, brain and spermatozoa.
CC   -!- CATALYTIC ACTIVITY: ATP + creatine = ADP + phosphocreatine.
CC   -!- SUBUNIT: Dimer of identical or non-identical chains. With MM being
CC       the major form in skeletal muscle and myocardium, MB existing in
CC       myocardium, and BB existing in many tissues, especially brain.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase C-terminal domain.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase N-terminal domain.
CC   -!- GENE_FAMILY: HOG000232165 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000030399;ENSMUST00000003643;ENSMUSP00000003643.
DR   EMBL; AK009950; - ;
DR   EMBL; BC132424; - ;
DR   EMBL; BC132426; - ;
DR   EMBL; CH466639; - ;
DR   EMBL; X03233; - ;
DR   UniProtKB/Swiss-Prot; P07310; -.
DR   EMBL; X03233; CAA26979.1; -; mRNA.
DR   IPI; IPI00127596; -.
DR   PIR; A23590; A23590.
DR   RefSeq; NP_031736.1; NM_007710.2.
DR   UniGene; Mm.2375; -.
DR   ProteinModelPortal; P07310; -.
DR   SMR; P07310; 2-381.
DR   IntAct; P07310; 1.
DR   STRING; P07310; -.
DR   PhosphoSite; P07310; -.
DR   SWISS-2DPAGE; P07310; -.
DR   PRIDE; P07310; -.
DR   Ensembl; ENSMUST00000003643; ENSMUSP00000003643; ENSMUSG00000030399.
DR   GeneID; 12715; -.
DR   KEGG; mmu:12715; -.
DR   CTD; 1158; -.
DR   MGI; MGI:88413; Ckm.
DR   InParanoid; P07310; -.
DR   OMA; IRASVMM; -.
DR   OrthoDB; EOG4R7V9X; -.
DR   PhylomeDB; P07310; -.
DR   NextBio; 281984; -.
DR   ArrayExpress; P07310; -.
DR   Bgee; P07310; -.
DR   CleanEx; MM_CKM; -.
DR   Genevestigator; P07310; -.
DR   GermOnline; ENSMUSG00000030399; Mus musculus.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; IDA:MGI.
DR   GO; GO:0046314; P:phosphocreatine biosynthetic process; IDA:MGI.
DR   InterPro; IPR000749; ATP-guanido_PTrfase.
DR   InterPro; IPR022415; ATP-guanido_PTrfase_AS.
DR   InterPro; IPR022414; ATP-guanido_PTrfase_cat.
DR   InterPro; IPR022413; ATP-guanido_PTrfase_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   Gene3D; G3DSA:1.10.135.10; ATP-gua_Ptrans; 1.
DR   Gene3D; G3DSA:3.30.590.10; ATP-gua_Ptrans; 1.
DR   PANTHER; PTHR11547; ATP-gua_Ptrans; 1.
DR   Pfam; PF00217; ATP-gua_Ptrans; 1.
DR   Pfam; PF02807; ATP-gua_PtransN; 1.
DR   SUPFAM; SSF48034; ATP-gua_Ptrans; 1.
DR   PROSITE; PS00112; PHOSPHAGEN_KINASE; 1.
DR   PROSITE; PS51510; PHOSPHAGEN_KINASE_C; 1.
DR   PROSITE; PS51509; PHOSPHAGEN_KINASE_N; 1.
DR   HOGENOMDNA; MOUSE7.PE551; -.
KW   ENSMUSG000000303995old_1320000031; ENSMUSP000000036431old_1320000031;
KW   A2RTA0_MOUSE; Q9D6U7_MOUSE; AK009950; BC132424; BC132426; CH466639;
KW   X03233;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Reference proteome; Transferase.
SQ   SEQUENCE   381 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPFGNTHNKF KLNYKPQEEY PDLSKHNNHM AKVLTPDLYN KLRDKETPSG FTLDDVIQTG
     VDNPGHPFIM TVGCVAGDEE SYTVFKDLFD PIIQDRHGGY KPTDKHKTDL NHENLKGGDD
     LDPNYVLSSR VRTGRSIKGY TLPPHCSRGE RRAVEKLSVE ALNSLTGEFK GKYYPLKSMT
     EQEQQQLIDD HFLFDKPVSP LLLASGMARD WPDARGIWHN DNKSFLVWVN EEDHLRVISM
     EKGGNMKEVF RRFCVGLQKI EEIFKKAGHP FMWNEHLGYV LTCPSNLGTG LRGGVHVKLA
     NLSKHPKFEE ILTRLRLQKR GTGGVDTAAV GAVFDISNAD RLGSSEVEQV QLVVDGVKLM
     VEMEKKLEKG QSIDDMIPAQ K
//

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