(data stored in ACNUC941 zone)

HOGENOM: PIG1_137_PE11

ID   PIG1_137_PE11                        STANDARD;      PRT;   416 AA.
AC   PIG1_137_PE11; Q29577; B2ZF48;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Creatine kinase U-type, mitochondrial; EC=2.7.3 2;AltName:
DE   Full=Acidic-type mitochondrial creatine kinase; Short=Mia-CK;AltName:
DE   Full=Ubiquitous mitochondrial creatine kinase; Short=U-MtCK;Flags:
DE   Precursor; (PIG1_137.PE11).
GN   Name=CKMT1;
OS   SUS SCROFA.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PIG1_137.PE11.
CC       Sus scrofa chromosome 1 Sscrofa9 partial sequence 133525077..134516218
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:KCRU_PIG
CC   -!- FUNCTION: Reversibly catalyzes the transfer of phosphate between
CC       ATP and various phosphogens (e.g. creatine phosphate). Creatine
CC       kinase isoenzymes play a central role in energy transduction in
CC       tissues with large, fluctuating energy demands, such as skeletal
CC       muscle, heart, brain and spermatozoa (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + creatine = ADP + phosphocreatine.
CC   -!- SUBUNIT: Exists as an octamer composed of four MTCK homodimers (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral
CC       membrane protein; Intermembrane side (By similarity).
CC   -!- MISCELLANEOUS: Mitochondrial creatine kinase binds cardiolipin (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase C-terminal domain.
CC   -!- SIMILARITY: Contains 1 phosphagen kinase N-terminal domain.
CC   -!- GENE_FAMILY: HOG000232165 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Sus_scrofa;ENSSSCG00000004703;ENSSSCT00000005194;ENSSSCP00000005068.
DR   EMBL; EU650786; - ;
DR   EMBL; F14801; - ;
DR   UniProtKB/Swiss-Prot; Q29577; B2ZF48; -.
DR   EMBL; EU650786; ACD02423.1; -; mRNA.
DR   EMBL; F14801; CAA23265.1; -; mRNA.
DR   GeneTree; ENSGT00550000074561; -.
DR   OrthoDB; EOG40VVPN; -.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; IEA:EC.
DR   InterPro; IPR000749; ATP-guanido_PTrfase.
DR   InterPro; IPR022415; ATP-guanido_PTrfase_AS.
DR   InterPro; IPR022414; ATP-guanido_PTrfase_cat.
DR   InterPro; IPR022413; ATP-guanido_PTrfase_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   Gene3D; G3DSA:1.10.135.10; ATP-gua_Ptrans; 1.
DR   Gene3D; G3DSA:3.30.590.10; ATP-gua_Ptrans; 1.
DR   PANTHER; PTHR11547; ATP-gua_Ptrans; 1.
DR   Pfam; PF00217; ATP-gua_Ptrans; 1.
DR   Pfam; PF02807; ATP-gua_PtransN; 1.
DR   SUPFAM; SSF48034; ATP-gua_Ptrans; 1.
DR   PROSITE; PS00112; PHOSPHAGEN_KINASE; 1.
DR   PROSITE; PS51510; PHOSPHAGEN_KINASE_C; 1.
DR   PROSITE; PS51509; PHOSPHAGEN_KINASE_N; 1.
DR   HOGENOMDNA; PIG1_137.PE11; -.
KW   ENSSSCG00000004703820036002503210000011;
KW   KCRU_PIG; B2ZF48_PIG; EU650786; F14801;
KW   ATP-binding; Complete proteome; Kinase; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Nucleotide-binding; Transferase;
KW   Transit peptide.
SQ   SEQUENCE   416 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAGPFSRLLS ARPGLRLLAL AGAGSLAAGF LLRPEPIRAA SERRRLYPPS AEYPDLRKHN
     NCMASHLTPA VYARLCDKTT PTGWTLDQCI QTGVDNPGHP FIKTVGMVAG DEETYEVFAE
     LFDPVIQERH NGYDPRTMKH TTDLDASKIR SGFFDERYVL SSRVRTGRSI RGLSLPPACT
     RAERREVERV VVDALSGLKG DLAGRYYRLS EMTEAEQQQL IDDHFLFDKP VSPLLTAAGM
     ARDWPDARGI WHNNEKSFLI WVNEEDHTRV ISMEKGGNMK KVFERFCRGL KEVERLIQER
     GWEFMWNERL GYILTCPSNL GTGLRAGVHI KLPLLSKDSR FPKILENLRL QKRGTGGVDT
     AATGSIFDIS NLDRLGKSEV ELVQLVIDGV NYLIDCERRL ERGQDIRIPP PLPNKH
//

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