Alignment of the gene Family HOG000252992 of HOGENOM

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Isoforms are ON
AILMEGL192669_1_2_PE1 NOISO ------------------------------------------------------------------------------------------------------------------------ AILMEGL194768_1_PE3 NOISO ----------------------------------------------------------------------------------------------------DLP-TPQVSE-----RRDPH ANOCA750_PE11 NOISO ------------------------------------------------------------------------------------------------------------------------ APIME_525_PE7 NOISO ASTDLSFGCIPAFYREVYEKICSSTSGNVEREVFKSLLVKSQLSSSVLSQIWELVDSK-TGYLTRSGLYKGLALVA-----------FAQQGKHPSDKLLENSESQELPVPVLGDLSEVT BOVIN25_44_PE13 NOISO ---------------------------------------------------------------MTGGAMDPLPTAPG----AAAAEAEVDEEADPP--AADSP-VPPVSE-----PRAPD CALJA2_58_PE10 NOISO ---------------------------------------------------------------------------------------------------ADLP-TPQAVEPQVIVQRAPA CANFA6_19_PE3 NOISO ---------------------------------------------------------------MTGGVMDRLSAEAGAAPVVAAAEAEADEEADPP--AAGLP-TPQISE-----RRDPY CAVPO30_12_PE10 NOISO ---------------------------------------------------------------------------------------------------TGSP-ALPVIE-----WEDLV CHICK14_PE93 NOISO ----------------------------------------------------------------------------------------------------------------VNEPRESE CIOIN89_PE119 NOISO ------------------------------------------------------------------------------------------------------------------------ CIOSAREFTIG_16_5_PE145 ISOFORMIN --MSELTGSVPPYYRDVYECLCQND--QISQNVLTQLLTKSGLDRAVLGKIWECIECK-SGSINRSNLYKALALVA-----------FAQQGKPVSANLLGNFAGQELPKPNLGDVSELR CIOSAREFTIG_16_5_PE146 ENSCSAVG00000011578 ------------------------------------------------------------------------------------------------------------------------ DANRE1_12_PE10 NOISO ------------------------------------------------------------------------------------------------------------------------ DANRE1_12_PE24 NOISO ------------------------------------------------------------------------------------------------------------------------ DANRE3_44_PE3 ENSDARG00000074842 MAGDINEGSVPSYYREVHQALCSASDERVPVNVFQRVFTRTSLPITVQNQILEHVNSS-DGFLSKVSLYKALALIA-----------LAQQGKPPSPKLLENF-IQDFPKPQLGEPKELH DANRE3_44_PE4 ISOFORMIN MAGDINEGSVPSYYREVHQALCSASDERVPVNVFQRVFTRTSLPITVQNQILEHVNSS-DGFLSKVSLYKALALIA-----------LAQQGKPPSPKLLENF-IQDFPKPQLGEPKELH DASNOGS_1522_PE1 NOISO -----------------------------------------------------------------------------------------------------------PPSTQAGEQRDTE DIPORGS_1473_PE2 NOISO ---------------------------------------------------------------MTGRAMDPLPAAA----VPAAAEVEADEEADPP--ATGLP-MPQDIE-----HRLSD FUGRU15_1_PE167 NOISO --------------------------------------------------------------------------------------------------------------PQLGDLKDLR GASACGROUPXI_15_PE26 NOISO ------------------------------------------------------------------------------------------------------------------VVRSPQ GORGO7_3_PE8 NOISO ------------------------------------------------------------------------------------------------------------------------ HORSE13_6_PE2 NOISO ----------------------------------------------------------------------------------------------------DLP-VPQVCE-----RRDPD HS7_PE149 ENSG00000106266 ---------------------------------------------------------------MTGRAMDPLPAAA----VGAAAEAEADEEADPP--ASDLP-TPQAIEPQAIVQQVPA HS7_PE150 ISOFORMIN --------------------------------------------------------------------MHPGLPST----L---------TCSCSL--MSDLP-TPQAIEPQAIVQQVPA LOXAF45_5_PE4 ISOFORMIN -----------------------------------------------------------------------------------------------------------------------E LOXAF45_5_PE5 ENSLAFG00000008778 -----------------------------------------------------------------------------------------------------------------------E MACEUGS_2179_PE1 NOISO -----------------------------------------------------------------------------------------------------------MPKPQVIEQREPA MACMU3_41_PE16 NOISO ---------------------------------------------------------------MTGRAMDPLPAAA----VGAAAEAEADEEEDPP--AADQL-TPQAIEPQAIVQQAAA MICMU7227_PE1 NOISO ---------------------------------------------------------------MTGRTMDQRQAAA----VAAAAEAEVDGEADPA--AAELQ-TPQV------TEQDPE MONDO6_75_PE3 NOISO --------------------------------------------------------------------------------------------------------SPDLPKPQVIEQREPD MOUSE5_PE3054 NOISO ---------------------------------------------------------------MTGRAMDPLPSPA----VAAAAEAEADEEADPP--ATGPR-TSQVTE-----WRALD NEMVE_5410_PE2 NOISO MAASLTFGSVPSFYREVYKIVCPNEENRVERDVLIKVLMKSSLPKPTLTLIWESVDPKNDGYVTRDGLYKALALSA-----------LAQQGKPVSEKALESFIDAELPRPSLGDLSDLK ORNAN2_29_PE1 NOISO --------------------------------------------------------------------LDQSPS----------AEIAHSKEKESG--LESFP-SAEFPKPQASKLREPE ORYLA8_8_PE14 NOISO ------------------------------------------------------------------------------------------------------------------------ OTOGAGS_12_PE3 NOISO ---------------------------------------------------------------MTGREMDQQPAVA----VGAAAEAEAEEEADPV--VADLL-MPQVTK-----DRDPE PANTR7_3_PE10 NOISO ---------------------------------------------------------------MTGRAMDPLPAAA----VGAAAEAEADEEADPP--AADLP-TPQAIEPQAIVQQAPA POEGU14_13_PE13 NOISO ----------------------------------------------------------------------------------------------------------------VNEPREAE PONPY7_3_PE6 NOISO ---------------------------------------------------------------MTGRAMDPLPAAA----VGATAEAEADEEADPP--AADLP-TPQAIEPQAIVQQAPA PROCAGS_1614_PE2 NOISO ---------------------------------------------------------------MTGRAMDPLPPAAI----AVAAELEAGEEEAGP-LAAXXX-XXXXXXXXXXXXXXXX PTEVAGS_12_PE3 NOISO ---------------------------------------------------------------MTGGAMDRLPAAA----VAAATEAEAAEEQDPL--AADLP-VPQVNE-----QRDLD RABIT7_131_PE1 NOISO ----------------------------------------------------------------------------------AAAEVEADEEADPP--AAGLP-RPQVLE-----QRDP- RAT12_PE266 NOISO ---------------------------------------------------------------MTGRAMDPLPSPA----VAAAAEAEADEEADPP--ATGPQ-TSQVTE-----WRNLD SORARGS_1510_PE1 NOISO ------------------------------------------------------------------------------------------------------------------------ SPETRGS_1988_PE3 NOISO ---------------------------------------------------------------MTGRAMDPLPAAA----VASATEAEADEEADPL--AAGSP-VPQVTD-----RRDPD STRPU_66545_PE1 NOISO ---------------------------------------------MVWFQIWDAVDSK-QGFITRGGLYKALALTA-----------LAQQGKQP---------NVKLLENYTG-QDLRK TETNG3_PE847 NOISO ------------------------------------------------------------------------------------------------------------------------ TRIAD_373_PE771 NOISO MCDTPLVDTVPSFYREVYQQTCQRGSGKVDKDVFVKVLMKSSLPKQTLSAIYECLGVRKDDDISREKLYKALALAA-----------LAQQGKTYNLEALDAIDSADYPTPSLGDLSDLK TURTRGS_8_PE4 NOISO ---------------------------------------------------------------MTGGAMDPIPAAPA----AAAAEPEADEEADPP--AADSP-VPQVSE-----PKAPD MATCH CONSENSUS ????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????

AILMEGL192669_1_2_PE1 NOISO ---MQM-PQGSPLLLALP-QQLLDGDTVRGELIAKKKGL-FWKHVEYEVSR------------------------------------------------------LLFKSSVYRPCKDFT AILMEGL194768_1_PE3 NOISO PTRMQM-PQGNPLLLSYTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV ANOCA750_PE11 NOISO ---MQA-PPGNPLLLSHTLQELLSKDTVQVELIPEKKGL-FVKHVEYEVSS------------------------------------------------------KRFNCSVYRRYNDFV APIME_525_PE7 NOISO LLAQRLHKGSNPAKLNLTYSDICNLDTIEVNLVPEKKGI-FLKHVEYQVTS------------------------------------------------------KRFNSIVYRRYNDFV BOVIN25_44_PE13 NOISO AGQMQV-PPGNPLLLSLTLQELLARDAVQVELVPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSCVYRRYNDFV CALJA2_58_PE10 NOISO PSRMQM-PQGNPLLLSHSLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV CANFA6_19_PE3 NOISO PNRMQM-PQGNPLLLSYTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFQSSVYRRYNDFV CAVPO30_12_PE10 NOISO PRSMQM-PQGNPLLLSFTLQELLARDSVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKTSVCRRYNDFV CHICK14_PE93 NOISO QFLMQA-PPGNPLLLPHTLQELLSKDSVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------KRFKCSVYRRYNDFV CIOIN89_PE119 NOISO ------------------------------------------------------------------------------------------------------------------------ CIOSAREFTIG_16_5_PE145 ISOFORMIN KLLHQT--KKSPTELDFTYHECCAFDSIDITLVPEKKGI-FLKHSEYEITS------------------------------------------------------RRNNSTVKRRYNDFV CIOSAREFTIG_16_5_PE146 ENSCSAVG00000011578 ------------------------------------------------------------------------------------------------------------------------ DANRE1_12_PE10 NOISO --KMHL-GQQGPLMDGLSLKE--LGDSVLVEIEPRRKGLPFLKHVEYRIVS------------------------------------------------------KCFQIPVQRRYSDFE DANRE1_12_PE24 NOISO ---MHL-GQQGPLMDGLSLKE--LGDSVLVEIEPRRKGLPFLKHVEYRIVS------------------------------------------------------KCFQIPVQRRYSDFE DANRE3_44_PE3 ENSDARG00000074842 SLKMQT-VQDSPLILSLTLAELLKKDTIKIELTPEKKGL-FLKHVEYQVTS------------------------------------------------------ERFTLTVYRRYSDFD DANRE3_44_PE4 ISOFORMIN SLKMQT-VQDSPLILSLTLAELLKKDTIKIELTPEKKGL-FLKHVEYQVTS------------------------------------------------------ERFTLTVYRRYSDFD DASNOGS_1522_PE1 NOISO PTRMQM-PPGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QXXXXXXXXXXXXXX DIPORGS_1473_PE2 NOISO SSRMQR-PQGNPLLLSYSLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV FUGRU15_1_PE167 NOISO ALKMQP-APEDVLTLSQTLDKLLASDFVQVELIPEKKGL-FLKHVEYQLTS------------------------------------------------------QRYKISVYRRYSDFD GASACGROUPXI_15_PE26 NOISO ALRMQP-ARDDALTLSQTLDKLLVGDAVQVELIPEKKGL-FLKHVEYQVTS------------------------------------------------------QRFKISVYRRYNDFD GORGO7_3_PE8 NOISO PSRMQM-PQGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV HORSE13_6_PE2 NOISO PSRMQM-PQGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFQSSVYRRYNDFV HS7_PE149 ENSG00000106266 PSRMQM-PQGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV HS7_PE150 ISOFORMIN PSRMQM-PQGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV LOXAF45_5_PE4 ISOFORMIN PTRMQM-LQGNPLLLSYSLQELLARDTVQVEVIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFQSSVYRRYNDFV LOXAF45_5_PE5 ENSLAFG00000008778 PTRMQM-LQGNPLLLSYSLQELLARDTVQVEVIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFQSSVYRRYNDFV MACEUGS_2179_PE1 NOISO SFRMQV-TQGNPLLLPHTLSELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------LRFKSSVYRRYNDFV MACMU3_41_PE16 NOISO PSRMQM-PQGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV MICMU7227_PE1 NOISO PSRMQM-PRGNPLLLSYTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV MONDO6_75_PE3 NOISO SFRMQM-PQGNPLLLSHTLQELLARDSVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFESSVYRRYNDFV MOUSE5_PE3054 NOISO PGRMQM-PQGNPLLLSYTLQELLAKDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV NEMVE_5410_PE2 NOISO KFSVQVQREQNPNILGYSYEELMALDNIEVELLAEKKGI-LLKHNEYHISSSIWESVDPKNDGYVTRDGLYKALALSALAQQGKPVSEKALESFIDAAGINIISDQRHNLTVSRRYNDFV ORNAN2_29_PE1 NOISO GFRMQM-PQGNPLLLSHTLQELLAKDTIQVELIPEKKGL-FLKHVEYEVTS------------------------------------------------------QRFKSSVYRRYNDFV ORYLA8_8_PE14 NOISO ---MQP-AQEDVLTISQTLDKLLERDKVQVELIPEKKGL-FLKHVEYQVTS------------------------------------------------------QRFKISVYRRYSDFD OTOGAGS_12_PE3 NOISO PNRMQM-PQGNPLLLSYTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QXXXXXXXXXXXXXX PANTR7_3_PE10 NOISO PSRMQM-PQGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV POEGU14_13_PE13 NOISO QFLMQT-PQGNPLLLSHTLQELLSKDSVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------KRFKCSVYRRYNDFV PONPY7_3_PE6 NOISO PSRMQM-PQGNPLLLSHTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV PROCAGS_1614_PE2 NOISO XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX------------------------------------------------------XRFQSSVYRRYNDFV PTEVAGS_12_PE3 NOISO PGRMQM-LQGNPLLLPHSLQELLAKDTVQVALVPERKGL-FLKHVEYEVSS------------------------------------------------------QRFGASVSRRYNDFV RABIT7_131_PE1 NOISO -----D-PTGGPLLLSYSLQDLLARDTVQVELVPEKKGL-FLK-VEYEVSS------------------------------------------------------QRFQASVYRRYNDFV RAT12_PE266 NOISO PRRMQM-PQGNPLLLSYTLQELLAKDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QRFKSSVYRRYNDFV SORARGS_1510_PE1 NOISO PRQKQR-LQG-ILVLLVSLRKLLDMYSVQVELFPEK-NW-FYKHEEYQVAS------------------------------------------------------QRFKSSVYRRYNDFV SPETRGS_1988_PE3 NOISO PSRMQM-PQGNPLLLSYTLQELLARDTVQVELIPEKKGL-FLKHVEYEVSS------------------------------------------------------QXXXXXXXXXXXXXX STRPU_66545_PE1 NOISO LSQDVR-RERAPNILNYNYAQLSALDHVTVDLIPEKKGL-LLKHVEYEVFS------------------------------------------------------RMYKSTVFRRYSDFA TETNG3_PE847 NOISO ---------------------------------PGEEGL-SLKHVEYQVTS------------------------------------------------------QRYKTSVYRRYSDFD TRIAD_373_PE771 NOISO LLNLRLQREKTPTLLNYTYRELEDLNSVNVEIVPEKKGL-FLKHVEYTVYN------------------------------------------------------ERTKSTVCRRYSDFC TURTRGS_8_PE4 NOISO SSRMQM-PPGNPLLLSLTLQELLARDAV-VELIPEKKGL-F-QHVEYEVSS------------------------------------------------------QRFKSCVYRRYNDFV MATCH CONSENSUS ???????????PL?L??????L???D???VEL?PEKKGL?FLKHVEY?V?S???????????????????????????????????????????????????????R????V?RRY?DF?

AILMEGL192669_1_2_PE1 NOISO VFHETLLPKIPYRGVPALPPKSLR-GA------HPEFSE-QRPALRCFITLVARHPCSP---RMWLFLSFSGPAVGNKLKASARCAGDDMNGKPPALP---------------------- AILMEGL194768_1_PE3 NOISO VFHEMLLQKFPYRMVPALPPKRVL-GA------DREFIEARRRALRRFINLVARHPPFSEDVALRLFLSFSGPDVQNKLKESAQCVGDEFLNCKLAPRA--------------------- ANOCA750_PE11 NOISO VFHEMLLQKFPYRMVPALPPKRML-GG----KSDREFIETRRRALKRFVNLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFMICKLATQA--------------------- APIME_525_PE7 NOISO SLHELLLARFPYRLIPKLPPKKIV-GA------DSQFLEERRRSLLRFLTVIARHPVVSKDHIVQFFFTYTGEETQHKIREVFRRVPDEFATSELSSRA--------------------- BOVIN25_44_PE13 NOISO VFHETLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFINLVARHPPFSEDTILKLFLSFSGPDVQNKLKESAQCLGDEFMNCRLAARA--------------------- CALJA2_58_PE10 NOISO VFQEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSVSASAPRVSLSRKPPELLFSSLRFQK--------------------- CANFA6_19_PE3 NOISO VFHEMLLHRFPYRMVPALPPKRVL-GA------DREFIESRRRALRRFINLVARHPPFSEDVALRLFLSFSGPDVQNKLKESTQCVGDEFMNCKLAPRA--------------------- CAVPO30_12_PE10 NOISO VFHEMLLHRFPYRMVPALPPKRML-GA------DREFIEGRRRALKRFINLVARHPPFSEDATLKLFLSFSGPDVQNKLREAAQGVGDEFLNCKLATRA--------------------- CHICK14_PE93 NOISO VFHEMLLQKFPYRMVPALPPKRML-GA------DREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQA--------------------- CIOIN89_PE119 NOISO -------------MVPRLPPKKMM-LS-----ADRDFIEARRKSLRRFLLIISRHPAMYDSALLQFFLTYTGHEVVHKIKEQFRGIPDEFERSSLTDQ---------------------- CIOSAREFTIG_16_5_PE145 ISOFORMIN AFHELLQQFFPYRMIPRLPPKKVMLSS------DHDFIEARRKSLRRFLHIISRHPAMYNSALLQFFLTYSGHEVVHKIKEQYRGSPDEYARSPVAAQA--------------------- CIOSAREFTIG_16_5_PE146 ENSCSAVG00000011578 -------------MIPRLPPKKVM-LS-----SDHDFIEARRKSLRRFLHIISRHPAMYNSALLQFFLTYSGHEVVHKIKEQYRGSPDEYARSPVAAQ---------------------- DANRE1_12_PE10 NOISO VFHGLLLQKFIYRMVPPLPPKRIL-KG------DREFNDSRRRGLQRFMTLVIRHPVLAGDQLVNIFLSASSADVQNKLRDSYKKTGDEFLISQIALHG--------------------- DANRE1_12_PE24 NOISO VFHGLLLQKFIYRMVPPLPPKRIL-KGVLNSLSDREFNDSRRRGLQRFMTLVIRHPVLAGDQLVNIFLSASSADVQNKLRDSYKKTGDEFLISQIALHG--------------------- DANRE3_44_PE3 ENSDARG00000074842 VFHELLLQRYSYRVVPALPPKRAL-KGVLTSVSEREFIEGRRRALTRFLNLVARHPVFSEDELVKTFLTFSGSDVQSKLRDACRKLGDEFMTCKFATQA--------------------- DANRE3_44_PE4 ISOFORMIN VFHELLLQRYSYRVVPALPPKRAL-KGVLTSVSEREFIEGRRRALTRFLNLVARHPVFSEDELVKTFLTFSGSDVQSKLRDACRKLGDEFMTCKFATQA--------------------- DASNOGS_1522_PE1 NOISO XXXXXXX--XXXXXXXXXXXXXXX-XX----XXDREFIEARRRALRRFINLVARHPPFSEDVVLKLFLSFSGPDVQNKLKESAQWVGDEFLNCKLATRA--------------------- DIPORGS_1473_PE2 NOISO VFHEMLLHKFPYRMVPALPPKRML-GA------DREFIEGRRRALKRFINLVARHPPFSDDVILKLFLSFSGSDVQNKLKEAAQCVGDEFMNCKLAARA--------------------- FUGRU15_1_PE167 NOISO VFHEVLLQRFSYRVVPAMPPKRML-KGVLTNVSEREFIEGRRRALGRFINLVARHPILSEDELLKTFLTFNGSDVQTKLRDAYKRMGDEFMTNRIATQA--------------------- GASACGROUPXI_15_PE26 NOISO VFHEVLLQRFAYRVVPALPPKRML-KG------ERDFIEGRRRALARFINLVARHPFFSEDELVKTFLAFSGSDVQSKLRDAYKKTGDEFMTNRVATLA--------------------- GORGO7_3_PE8 NOISO VFQEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLATRA--------------------- HORSE13_6_PE2 NOISO VFHEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFINLVARHPPFSEDVVLKLFLSFSGPDVQNKLKESAQLVGDEFMNCKLATRA--------------------- HS7_PE149 ENSG00000106266 VFQEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLATRA--------------------- HS7_PE150 ISOFORMIN VFQEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLATRA--------------------- LOXAF45_5_PE4 ISOFORMIN VFHEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFINLVARHPPFSEDVVLKLFLSFSGPDVQNKLKESAQCVGDEFLHSRLATRA--------------------- LOXAF45_5_PE5 ENSLAFG00000008778 VFHEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFINLVARHPPFSEDVVLKLFLSFSGPDVQNKLKESAQCVGDEFLHSRLATRA--------------------- MACEUGS_2179_PE1 NOISO VFHEMLLQKFPYRMVPALPPKRML-GA------DREFIETRRRALKRFINLVARHPPFSDDVVLKLFLSFSGSXXXXXXXXXXXXXX-XXXXXXXXXXX--------------------- MACMU3_41_PE16 NOISO VFQEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFMNCKLATRA--------------------- MICMU7227_PE1 NOISO VFHDMLLHRFPYRMVPALPPKRML-GA------DREFIEARRRALKRFINLVARHPPFSEDVILKLFLSFSGSDVQNKLKESAQFVGDEFMNCKLATRA--------------------- MONDO6_75_PE3 NOISO VFHEILLQKFPYRMVPALPPKRML-GA------DREFIETRRRALKRFINLVARHPPFSEDVVLKLFLSFSGSDVQNKLKESVQCVGDEFMICKLATRA--------------------- MOUSE5_PE3054 NOISO VFHEVLLHKFPYRMVPALPPKRVL-GA------DREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFMNCKLAARA--------------------- NEMVE_5410_PE2 NOISO AFHDLLISRFPYRMVPKLPPKKLM-GA------NKEFIEARRRALKRFLTLVARHPILCNDKIVVLFFTIKGSDIGQKMKDQFKMYPDEFATSPLSPRI--------------------- ORNAN2_29_PE1 NOISO VFHEMLLQKFPYRMVPALPPKRML-GA------DREFIETRRRALKRFINLVARHPPFSEDVILKLFLSFSGSDVQNKLKESAQCVGDEFMICKLATQA--------------------- ORYLA8_8_PE14 NOISO VFHEVLLQRFAYRVVPALPPKRML-KG------EREFIEGRRRALGRFINLVACHPFFSVDELVKTFLTFSGSDVQTRLRDTYKKMGDEFMTNRIATLA--------------------- OTOGAGS_12_PE3 NOISO XXXXXXX--XXXXXXXXXXXXXXX-XX----XXDKEFIEARRRALKRFINLVARHPPFSEDVMLKLFLSFSGSXXXXXXXXXXXXXXX-XXXXXXXXXX--------------------- PANTR7_3_PE10 NOISO VFQEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLATRA--------------------- POEGU14_13_PE13 NOISO VFHEMLLQKFPYRMVPALPPKRML-GA------DREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFVTCRLATQA--------------------- PONPY7_3_PE6 NOISO VFQEMLLHKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFMNCKLATRA--------------------- PROCAGS_1614_PE2 NOISO VFHEMLLHKFPYRMVPALPPKRVL-GA------DREFIEARRRALKRFINLVARHPPFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLHCKLATQA--------------------- PTEVAGS_12_PE3 NOISO VFHDLLLQKFPYRMVPALPPKKML-GA------DREFIEARRRALKRFINLVARHPPFSEDVVLKLFLSFSGPDVQSKLKESAQCMGDEFTNCKLATRA--------------------- RABIT7_131_PE1 NOISO VFREVLLHKFPYRLVPALPPKRML-GA------DRECIEGCRRALKRFLNLVAQHPPLCEDGLPQLFLCFSGPDVP------VQCLGDEFMSCELAARA--------------------- RAT12_PE266 NOISO VFHEVLLHKFPYRMVPALPPKRVL-GA------DREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFTNCKLAARA--------------------- SORARGS_1510_PE1 NOISO VLHEMLLHKFPYRMVPALPPKRVL-GA------DREFIEARRRALKRFINLVARHPRLADDALLRLFLAFGGSXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- SPETRGS_1988_PE3 NOISO XXXXXXX--XXXXXXXXXXXXXXX-XX----XXDREFIEGRRRALKRFINLVARHPPFSEDTILKLFLSFSGSXXXXXXXXXXXXXXX-XXXXXXXXXX--------------------- STRPU_66545_PE1 NOISO AMSDMLINCYPYRMVPRLPPKKML-GA------NREFIEQRRKALVRFLTLVVRHPTFHGSEVIRFFLTFTGSDMQHRIKEQFRGIPDEFVTSKLAAQAKDMQHRIKEQFRGIPDEFVTS TETNG3_PE847 NOISO VFHEVLLQRFSYRVVPAMPPKRML-KG------EREFIEGRRRGLGRFINLVARHPIFSEDELLKTFLTFNGSDVQTKLRDAYKRTGDEFMTNRIATQA--------------------- TRIAD_373_PE771 NOISO ALHEVLLQRFPYRAIPRLPPKKLA-G---------RFLEARCRALRRYLSLICRHPVVHDSEIVVYFLTAGVSDFQNKMKDKFRNLPDEFVTSPLAGKA--------------------- TURTRGS_8_PE4 NOISO VFHEMLLQKFPYRMVPALPPKRML-GA------DREFIEARRRALKRFINLVARHPPFSEDVVLKLFLSFSGPDVQNKLKECAQCVGDEFMNCKLAARA--------------------- MATCH : .* :: :: ** *: CONSENSUS ?F???LL??F?YR?VP?LPPK?????????????REFIE?RRRAL?RF??LVARHP????D?????FL?FSG??V??K?????????DEF?????A????????????????????????

AILMEGL192669_1_2_PE1 NOISO -----AKDFLPADIQTLFAVRRELIRNISNSFHKLCDLAEQIAASAIDNAADLMCRK-KLS----ALGSDTTPLPSWEQRVSSTGTT-----ERPVIEFALL----AA-QQDEQEENEVV AILMEGL194768_1_PE3 NOISO ------KDFLPADIQTQFAVSRELIRNVYNSFHKLRDRAERIAARAIDNAADLLIFGKELS----ALGSDTTPLPSWASLNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV ANOCA750_PE11 NOISO -----QADFLPADIQVQFAASRELIRNIYNSFYKLRDRAERIASRAVDNAADLLIFGKELS----ALGSDTTPLPSWAALNSSAWGNLKQALRGLSVEFALL-ADKAV-QQGKQEESDVV APIME_525_PE7 NOISO ------KELVPPETLTEFANSRDQIRVILLGISRLKNIADCLAIRSHSYAVDMAELGTQLS----NLASEPHGTTTWATGGSTIWQEMKKGFHIISKEFNLL-STRAL-QQAVREETMVC BOVIN25_44_PE13 NOISO ------KDFLPADIQTQFAMSRELIRNIYNSFHKLRDRAERMVSRAIDNAADLLIFGKELS----ALGSDTTPLPSWASLNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV CALJA2_58_PE10 NOISO -----QKASIGVKVRACCLVSISWESGLQATHISLKDRGSGAQKRAMGDGAFVLVKGTCID----GLGHICRSLPSGWLHCRCGWGSVVGCAGLVSIKTAGLRGVSAW-SWGKQEENDVV CANFA6_19_PE3 NOISO ------KDFLPADIQTQFAVSRELIRNIYNSFYKLRDRAERIASRAIDNAADLLVFGKELS----ALGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV CAVPO30_12_PE10 NOISO ------KDFLPTDIQTQFAMSRELIRNLYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDMTPLPSWATLHLSTWASLKQAMKGLSVEFAVL-ADKAA-QQGKQEENDVV CHICK14_PE93 NOISO ------KDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELS----ALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALL-ADKAV-QQGKQEENDVV CIOIN89_PE119 NOISO -----TKDLVPPETQTEFAASKEHIRQITTHVVKLRDMATRISERSKGNAADILGFGKELI----AIGNDGTTASAWATGGNDVIATLKRAFRSLSHEFSLI-SEKHS-LQGIREEEGVL CIOSAREFTIG_16_5_PE145 ISOFORMIN ------KDLVPPETQAEFAVSKEQIRQITSHVVKVRDMANRISERSKGNATDML------------------------------------------------------------------ CIOSAREFTIG_16_5_PE146 ENSCSAVG00000011578 -----AKDLVPPETQAEFAVSKEQIRQITSHVVKVRDMANRISERSKGNATDMLGFGKELI----AIGNDATVASRWGTGGNNVLNLLKQSFRSLSVEFAGI-SEKHA-LQGIREEEGVV DANRE1_12_PE10 NOISO ------KVYLPEDIQSQAAANREVIASIHSSFYKLRDVAERMAQRSRENSTDLLMFGKDLS----ELGSDTSDLPEDAIV-SKAWKTQRKSLVELSGEFGLL-ADKAAHQQGTREEDEVV DANRE1_12_PE24 NOISO ------KVYLPEDIQSQAAANREVIASIHSSFYKLRDVAERMAQRSRENSTDLLMFGKDLS----ELGSDTSDLPEDAIV-SKAWKTQRKSLVELSGEFGLL-ADKAAH-QGTREEDEVV DANRE3_44_PE3 ENSDARG00000074842 ------KDYLPADIQSQFSSSRQLIRNIHSSFQKLRDRAEKMAERSKDNATDLLMFGKELS----FLGSDESPVPILVSG-RNPWSALRHSVKGLSVDFSAL-SEKAA-RQGRREEDEVV DANRE3_44_PE4 ISOFORMIN ------KDYLPADIQSQFSSSRQLIRNIHSSFQKLRDRAEKMAERSKDNATDLLMFGKELS----FLGSDESPVPILVSG-RNPWSALRHSVKGLSVDFSAL-SEKAA-RQGRREEDEVV DASNOGS_1522_PE1 NOISO ------KDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRATDSAADLLVFGKELS----ALGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALL-ADKAA-QQXXXXXXXXX DIPORGS_1473_PE2 NOISO ------KDFLPADIQTQFAMSRELIRNIYNSFYKLRDRAERMASRAIDNASDLLIFGKELS----ALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV FUGRU15_1_PE167 NOISO ------KEYLPADIQAQFSTSRELIKKIHNSFNRLRDRAEKMAERSKENATDLLMFGRELS----LLGSDGSSLPPWASS-QATWGTLRESLKSLSVEFAVL-SDKAA-QQGSRENDDVV GASACGROUPXI_15_PE26 NOISO ------KEYLPADIQAQFSTSRELIRNIHNSFQKLRDRAEKMAERSKENATDLLMFGRELS----TLGSDASPLPSLASS-QSTWGALRRSLRSLSVEFAAL-SDKAA-QQGRREEDDVV GORGO7_3_PE8 NOISO ------KDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELRSLGGSCPSTSVPGGSLGAFTLSRGGCQRQNRKVLLIKRALC-ASWTS-HEGKQEENDVV HORSE13_6_PE2 NOISO ------KDFLPADIQTQFAISRELIRNIYNSFYKLRDRAERIASRAIDNAADLLIFGKELRQVTLALGSDTTPLPSWATLNSSAWSFLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV HS7_PE149 ENSG00000106266 ------KDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGSDTTP----LPSWAALNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV HS7_PE150 ISOFORMIN ------KDFLPADIQAQFAISRELIRNIYNSFHKLRDR---------------------------------------------------------------------------------- LOXAF45_5_PE4 ISOFORMIN ------KDFLPADIQVQFAASRELIRNIYNSFYKLRDRAERIASRAIDNAADLLIFGKEVA----ALGSDTTPLPSWASLSSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEESDVV LOXAF45_5_PE5 ENSLAFG00000008778 ------KDFLPADIQVQFAASRELIRNIYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWASLSSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEESDVV MACEUGS_2179_PE1 NOISO -----XXDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWATMNNSTWGTLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV MACMU3_41_PE16 NOISO ------KDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGSDTTP----LPSWAALNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV MICMU7227_PE1 NOISO ------KDFLPADIQTQFAVSRELIRNIYNGFYKLRDRAERIASRAIDNAADLLIFGKELSALGSDTT----PLPSWATLNSSTWGALKQALKGLSVEFALL-ADKAA-QQGKQEENDVV MONDO6_75_PE3 NOISO ------KDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNAADLLIFGKELRQV--ALGSDTTPLPSWATMNNSTWGTLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV MOUSE5_PE3054 NOISO ------KDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALL-ADRAA-QQGKKEENDVV NEMVE_5410_PE2 NOISO ------KELVPMDVQASFNASKKQINALHNSVEKMKDVADHLTARTLGFSSDMLYFAKELS----ALSNDSIPTTVWACGNNDSWGHLKHGFNGLTGHFSKL-SDKAA-EWFRREDVGCG ORNAN2_29_PE1 NOISO ------KDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWATLNNSTWGTLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV ORYLA8_8_PE14 NOISO ------KEYLPADIQAQFSTSRELIRNIHNSFQRLRDRAEKMAERSQENATDLLLFGQELS----TLGSETSPLPPLAPT-QSTWGALCESFKSLSVEFVVL-SDKAT-QQGRREEDDVV OTOGAGS_12_PE3 NOISO -----XXDFLPADIQTQFAVSRELIRNIYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWNTLNSSTWGALKQALXXXXXXXXXX-XXXXX-XXGKQEENDVV PANTR7_3_PE10 NOISO ------KDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGSDTTP----LPSWAALNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV POEGU14_13_PE13 NOISO ------KDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELS----ALGSDTTPLPSWAALNNNTWGTLKQALKGLSVEFALL-ADKAV-QQGKQEENDVV PONPY7_3_PE6 NOISO ------KDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGSDTTP----LPSWAALNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV PROCAGS_1614_PE2 NOISO ------KDFLPADIQVQFAASRELIRNIYNSFYKLRDRAERIASRAIDNAADLLMFGKELS----ALGSDTTPLPSWAALSGSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEESDVV PTEVAGS_12_PE3 NOISO ------KDFLPADIQTQFAVSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWAALHSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKKEENDVV RABIT7_131_PE1 NOISO ------EDFLPADVHAQFAVSRELIRNIYNSFHKLRDRAEQMAARAEDNTANLLIFGKELS----ALGSDTTPLPSWAALHSSTWGSLKQALTGLSVEFTLL-ADGAA-LQGEQEENDVV RAT12_PE266 NOISO ------KDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELRQVTLALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALL-ADKAA-QQGKKEENDVV SORARGS_1510_PE1 NOISO -----XXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALGSDTTPLPSWATQHSSTWGSLKQALRGLSVEFALL-ADKAA-EQGRQEEIDVV SPETRGS_1988_PE3 NOISO -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV STRPU_66545_PE1 NOISO KLAAQAKDLVPMDTQVQFGNSREQIKSLYNSMNLIKGFVDQITMRAMGNAADTLSFAKELS----SLGGDSQPASAWAMGHNDSWPNLKSGLKSVAVEFASL-SDKYT-NQGKRLNEGVA TETNG3_PE847 NOISO ------KEYLPADIQAQFLTSREVIKNIHNSFNRLRDRAETMAERSKENAADLLMFGRELS----VLGSDGSSLPSWASS-QSSWGALRQSLKSLSVEFTVL-SDKAA-QQGRREEDDVV TRIAD_373_PE771 NOISO ------KDLVPIDTQVSFNESKELLRNVLGSVSKLREIIENIITRSGVDARDWQQFGSELS----NLANESHASSAWACGNSHTWNQLKGVFKSLTGYFNEV-ADIGI-NQIQGAEDGSF TURTRGS_8_PE4 NOISO ------KDFLPADIQTQFAISRELIRNIYNSFHKLRDRAERMVSRTIDNAADLLIFGKELS----ALGSDTTPLPSWATLNSSTWGSLKQALKGLSVEFALL-ADKAA-QQGKQEENDVV MATCH CONSENSUS ??????K???P?D?Q??F??SRE?IR????S??KLRD?AE????R???NA?D?L?FG?EL??????????????P??A??????W??L??????LS?EF??L????A???QG??EE??VV

AILMEGL192669_1_2_PE1 NOISO EKLKLFLDLLQSK-DLGER-GRAVLDKQQRPRPRDSLPKRPVMSLSLTV-------QQL------------QSHVRSSFSLRGLHQEMELAHASLPLTSHLL-AFVTSLIQGHKE--MSK AILMEGL194768_1_PE3 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAAVQSREP-DSVEQLESRIVEQENAIQTMELRSYFSLYCLHQEMQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK ANOCA750_PE11 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKRQMMSASVQNKEP-ESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKE--MSK APIME_525_PE7 NOISO ERLNLLLDVLVAHRILCERHERGVSADHQRALSTMLSLKKRQMQGVIRGTDS-DTVEYLENKMVAQESVIANVELRNCFSLHCLHMETQLVHAHLEILATVLQSLVNVQIRGHSE--LAE BOVIN25_44_PE13 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMVSAAVQSREP-ESMEQLESRIVQQENVIQTMELRSHFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK CALJA2_58_PE10 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAAVQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKE--MSK CANFA6_19_PE3 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAAVQSREP-DSVEQLESRIVEQENAIQTMELRSYFSLYCLHQEMQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK CAVPO30_12_PE10 NOISO EKLNLFLDLLQAYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAAVQNCEP-ESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK CHICK14_PE93 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEP-ESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKE--MSK CIOIN89_PE119 NOISO DQLSMLVDILQAYHNLCDRHERGVLRDHHSALKRYGMMKTKRMAATVTNMEQ-GGVDRIESKILAQEHEIANRENRNFFALHCIHLETQLVYANMQILSEVVGTLVATQIKGHKE--MMK CIOSAREFTIG_16_5_PE145 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CIOSAREFTIG_16_5_PE146 ENSCSAVG00000011578 DQLYVLSDLLQAYHDLCERHERGVLRDHHSALKKYGAMKTKRMAATVTNMEQ-GGVDKIESKIQAQENEIANRENRSFYSLHCIHLETQLVYANMQILSEVVATLVATQIKGHQE--MAK DANRE1_12_PE10 NOISO EKLNLLLEQLQSYKDLCDRHDSGVLLEHQRAFEKRSGP------VGTHLKYQ-NSIEQPESRLSQQENTIITMEMRSYFSLLCLHQETQLVFTNLPLVTSILGTFVNSQIQGHKE--MGD DANRE1_12_PE24 NOISO EKLNLLLEQLQSYKDLCDRHDSGVLLEHQRAFEKRSGP------VGTHLKYQ-NSIEQPESRLSQQENTIITMEMRSYFSLLCLHQETQLVFTNLPLVTSILGTFVNSQIQGHKE--MGD DANRE3_44_PE3 ENSDARG00000074842 EKLDMFLDLLQSYRDLCERHEKGVLHDHQRALQKYGIMKRQIMSATVQPKEQ-LSVEQLESRIVQQENAIQAMELRNYFSLFCLHQESQLIFTYLPITSHICIPS--------------- DANRE3_44_PE4 ISOFORMIN EKLDMFLDLLQSYRDLCERHEKGVLHDHQRALQKYGIMKRQIMSATVQPKEQ-LSVEQLESRIVQQENAIQAMELRNYFSLFCLHQESQLIFTYLPITSHI------------------- DASNOGS_1522_PE1 NOISO XXXXXXXXXXXXXXDLCERHEKGVLHKHQRALHKYSLMKKQMMSAAVQSREP-EAVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKE----- DIPORGS_1473_PE2 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAA-HGREP-ETVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK FUGRU15_1_PE167 NOISO EKLNLFLDLLQSYRDLCERHEKGVLHEHQRALHKYSVMKRQMMSATVQPKEQ-ASVEQLESRIVQQENAIQTMELRNYFSLFCLHQETQLIFIYLPITSHILGAFVNSQVQGHRE--MGQ GASACGROUPXI_15_PE26 NOISO EKLNLFLDLLQSYRDLCERHEKGVLHEHQRALHKYGVMKRQMMSATVQPKEQ-ASVEQLESRIVQQENAIQTMELRNYFSLFCLHQETQLIFVYLPITSHILGAFVNSQVQGHRE--MGA GORGO7_3_PE8 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKE--MSK HORSE13_6_PE2 NOISO EKLNLFLDLLQSYKDLCARHEKGLLHKPQRALHSYSLMKRPASGTAGQTREP-ESVQQLESRILEQENAIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK HS7_PE149 ENSG00000106266 EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKE--MSK HS7_PE150 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ LOXAF45_5_PE4 ISOFORMIN EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMVSAA-HSREP-EAVEQLESRIVEQENAIQTMELRNHFSLYCLHQETQLVHAYLPLTSHILGAFVNSQIQGHKEATMSK LOXAF45_5_PE5 ENSLAFG00000008778 EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMVSAA-HSREP-EAVEQLESRIVEQENAIQTMELRNHFSLYCLHQETQLVHAYLPLTSHILGAFVNSQIQGHKE--MSK MACEUGS_2179_PE1 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILGAFVNSQIQGHKE--MSK MACMU3_41_PE16 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAAAQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKE--MSK MICMU7227_PE1 NOISO EKLNLFLDLLQSYKDLCERHERGVLHKHQRALHKYSLMKRQMMSAAVQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILGAFVNSQIQGHKE--MSK MONDO6_75_PE3 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNREP-ESVEQLESRIVEQENAIQIMELRNYFSLYCLHQETQLIHVYLPLTSHILGAFVNSQIQGHKE--MSK MOUSE5_PE3054 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAA-HGREP-ESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK NEMVE_5410_PE2 NOISO EVLALFLELTTSYKELCDRHEKGVLKDHQNSLHKMQQIKKRQISAQAKGQE--NMVDALESKIIEQEVDISNMENRNFFSLHCLQMETQLVHANLKMIAVALKKMVYSNALGNKE--VAQ ORNAN2_29_PE1 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILGAFVNSQIQGHKE--MSK ORYLA8_8_PE14 NOISO EKLNFFLDLLQSYRDLCERHEKGVLHEHQRALQKYGVMKRQMMSATVQSKEH-ATVEQLESRIVQQESAIQTMELRNYFSLFCLHQETQLIFTCLPITSHILGAFVSSQVQGHKE--EKM OTOGAGS_12_PE3 NOISO EKLNLFLDLLQSYKDLCERHERGVLHKHQRALHKYSLMKRQM-SAAVQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILGAFVNSQIQGHKE----- PANTR7_3_PE10 NOISO EKLSLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKE--MSK POEGU14_13_PE13 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEP-ESVEQLESRIVEQENAIITMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKE--MSK PONPY7_3_PE6 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKE--MSK PROCAGS_1614_PE2 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMVSAA-HSREP-ESVEQLESRIVEQENAIQTMELRNHFSLYCLHQETQLVHAYLPLTSHILGAFVNSQIQGHKE--MSK PTEVAGS_12_PE3 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMRRQM-SAAVHGQQP-EAVQQLESRIVEQESTIQTMELRHAFSLYCLHQETQLVHAHLPLTSHILGAFVNSQIQGHKE--MSK RABIT7_131_PE1 NOISO EKLNFFLDLLQSFKDLCERHEKGVLHKHLRALHKYSLMKRQMMSATVQSREP-DAVEQLESRIVEQQSANQTMELRNYFSLYCLHQETQLVHVYLP-TSHILRAFVNSQIQGHKE--MSK RAT12_PE266 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAA-HGREP-ESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKE--MSK SORARGS_1510_PE1 NOISO EKLNLFLDLLQSYRDLCERHERGVLHKHQRALHRYGLMRRQMLSAAVQSREP-QSVEQLESRIVEQESAIQIMELRNHFSLYCLHQETQLVHAYLPLTSHILGAFVNSQIQGHRE--MSK SPETRGS_1988_PE3 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRTLHKDGLMKRQ----AVSNREP-ESVEQLESRILEQENMIQTMELRNYFSLYCLHQETQLIHAYLPLTSHILGAFVNSQIQGHKE--MGK STRPU_66545_PE1 NOISO EKFWLFLDLLQAYKASFNW----------------------------------------------------------------------------------------------------- TETNG3_PE847 NOISO EKLSLFLDLLQSYRDLCERHEKGVLHEHQRALHKYGVMKRQMMSATVQPKEQ-ASVEQLESRIVQQENAIQTMELRNYFSLFCLHQETQLIFIYLPITSHILGAFVNSQVQGHTE--MGQ TRIAD_373_PE771 NOISO EIFNQFMDILTSYKDLCDRHEKGVIKDHQSALQKMSSMKKRQISAQAKGHEAGNTVDQLESRIIEQESEISNMEFRNYYSLHCVHMETQLVHANMELFALSFQELISQQIKNHKE--VLT TURTRGS_8_PE4 NOISO EKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQLMSAAVQNREP-ESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVSSQIQGHKE--XXX MATCH CONSENSUS EKL??FLDLLQSY?DLCERHE?GVL??HQRAL?K???MK?????A?????E????V?QLESRI??QE??I??ME?R??FSL?CLHQETQL????LP??S?IL???V?SQ??GH?E?????

AILMEGL192669_1_2_PE1 NOISO VG-NGLKPKLNCF-MGPSPSLTPRRS-------QQAGISPH-- AILMEGL194768_1_PE3 NOISO VW-NDLKPKLSFLFAGPNSSLTPPRC----P---RDGVSPH-- ANOCA750_PE11 NOISO VW-NELTPKLSCLFAGSSNMQTPPLS----T--QD-------- APIME_525_PE7 NOISO VW-KLIEPTIMKCLPEKSTNGSNGIS----------------- BOVIN25_44_PE13 NOISO VW-NDLQPKLRCLFVGPHGAPAPPRP----P---QDGLSAH-- CALJA2_58_PE10 NOISO VW-NDLRPKLSCLFAGPHSALTPPRSPPQSP--PEDGLCPH-- CANFA6_19_PE3 NOISO VW-NDLKPKLNCLFAGPNSSLTLPRS----P---QDGVSPH-- CAVPO30_12_PE10 NOISO VW-NDLKPKLSCLFSGPHSALTPPRS----P--AEDSLCPH-- CHICK14_PE93 NOISO VW-NELKPKLSCLFVGSSNMPTPPLS----P--PDGNFFSN-- CIOIN89_PE119 NOISO LW-EDVAPRVTDLLPNETR------------------------ CIOSAREFTIG_16_5_PE145 ISOFORMIN ------------------------------------------- CIOSAREFTIG_16_5_PE146 ENSCSAVG00000011578 LW-EDLAPRVSNMLPSELKENGAKSP--NRP------SSPR-- DANRE1_12_PE10 NOISO VW-GDLHPKLKDLF----------------------------- DANRE1_12_PE24 NOISO VW-GDLHPKLKDLFQSADEASSRSSSQTNSSGGQKSCAVNGST DANRE3_44_PE3 ENSDARG00000074842 ------------------------------------------- DANRE3_44_PE4 ISOFORMIN ------------------------------------------- DASNOGS_1522_PE1 NOISO ------------------------------------------- DIPORGS_1473_PE2 NOISO VW-NDLKPKLSCLFAGPHGTLTPPGS----P--QEDGVCPH-- FUGRU15_1_PE167 NOISO VW-NELQPKLGCLFGSNNGLKMPPPRHQ---GEPEDVIWPH-- GASACGROUPXI_15_PE26 NOISO VW-NELEPKLGCLFGG--------------------------- GORGO7_3_PE8 NOISO VW-NDLRPKLSCLFAGPHSTLTPPCS----P--PEDGLCPH-- HORSE13_6_PE2 NOISO VW-NDLKPKLSCLFAGPNSTLTPPRS----P---QDGVSPH-- HS7_PE149 ENSG00000106266 VW-NDLRPKLSCLFAGPHSTLTPPCS----P--PEDGLCPH-- HS7_PE150 ISOFORMIN ------------------------------------------- LOXAF45_5_PE4 ISOFORMIN VW-NDLKPKLHCLFAGPSGTLTLPRS----T--QEDCLLPR-- LOXAF45_5_PE5 ENSLAFG00000008778 VW-NDLKPKLHCLFAGPSGTLTLPRS----T--QEDCLLPR-- MACEUGS_2179_PE1 NOISO VW-NELKPKLSCLFAGPNNMPTPPRS----P--QEGNVFPH-- MACMU3_41_PE16 NOISO VW-NDLRPKLSCLFAGPHSALTPPCS----P--PEDGLCPH-- MICMU7227_PE1 NOISO VW-NDLKK-LSC--AGPHSALT--RS----P--PEDGVCPH-- MONDO6_75_PE3 NOISO VW-NELKPKLSCLFVGPNNLPTPPRS----P--QEGNLFSH-- MOUSE5_PE3054 NOISO VW-NDLKPKLSCLFAGPHSVLTPPRS----P--QEDGVCPH-- NEMVE_5410_PE2 NOISO VW-AEIQPTMENLVPKDSGSSKHSPP--GSP---SL-M----- ORNAN2_29_PE1 NOISO VW-NELKPKLSCLFVGPNNMPTPPRS----P--QEDNLFSH-- ORYLA8_8_PE14 NOISO KYFCKLNCKNDCIK-KNPNLNFPP------------------- OTOGAGS_12_PE3 NOISO ------------------------------------------- PANTR7_3_PE10 NOISO VW-NDLRPKLSCLFAGPHSTLTPPCS----P--PEDGLCPH-- POEGU14_13_PE13 NOISO VW-NELKPKLSCLFVGSSSMPTPPLS----P--PEGNFFSN-- PONPY7_3_PE6 NOISO VW-NDLRPKLSCLFAGPHSALTPPCS----P--PEDGLCPH-- PROCAGS_1614_PE2 NOISO VW-NDLKPKLHCLFAGPGSAVTLPSP---------DSLLPR-- PTEVAGS_12_PE3 NOISO VW-DDLKPKLHCLFAGPNSLTLPG---------SRDGLSPH-- RABIT7_131_PE1 NOISO VW-NELEPKLSCLFAGPHSTTAATAG----G--PAGQLCPH-- RAT12_PE266 NOISO VW-NDLKPKLSCLFAGPHSVLTPPRS----P--QEDGMCPH-- SORARGS_1510_PE1 NOISO VW-NDLKPKLSCLFVGPHSALTPPSSPQ-------DGPAPH-- SPETRGS_1988_PE3 NOISO VW-DDLKPKLSCLFAGPHNALTPPRS----P---QDGVCPH-- STRPU_66545_PE1 NOISO ------------------------------------------- TETNG3_PE847 NOISO VW-NELQPKLGCLF----------------------------- TRIAD_373_PE771 NOISO ML-I--------------------------------------- TURTRGS_8_PE4 NOISO XX-XXXXXXXXXXXXXXXXXXXXXXS----P---QDGLSPH-- MATCH CONSENSUS ???????????????????????????????????????????


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