bpp-phyl3
3.0.0
|
The Goldman and Yang (1994) substitution model for codons. More...
#include <Bpp/Phyl/Model/Codon/GY94.h>
Public Member Functions | |
GY94 (std::shared_ptr< const GeneticCode > gc, std::unique_ptr< CodonFrequencySetInterface > codonFreqs) | |
virtual | ~GY94 () |
GY94 (const GY94 &gy94) | |
GY94 & | operator= (const GY94 &gy94) |
GY94 * | clone () const override |
std::string | getName () const override |
Get the name of the model. More... | |
const SubstitutionModelInterface & | substitutionModel () const override |
std::shared_ptr< const GeneticCode > | getGeneticCode () const |
double | getCodonsMulRate (size_t i, size_t j) const |
std::string | getParNameFromPmodel (const std::string &name) const |
get the name of a parameter from its name in a submodel More... | |
std::string | getPmodelParName (const std::string &name) const |
get the name of a parameter in the submodel from its apparent name More... | |
const FrequencySetInterface & | frequencySet () const override |
const BranchModelInterface & | model () const override |
bool | hasIndependentParameter (const std::string &name) const |
const ParameterList & | getIndependentParameters () const |
size_t | getNumberOfIndependentParameters () const |
void | aliasParameters (const std::string &p1, const std::string &p2) |
void | aliasParameters (std::map< std::string, std::string > &unparsedParams, bool verbose) |
void | unaliasParameters (const std::string &p1, const std::string &p2) |
ParameterList | getAliasedParameters (const ParameterList &pl) const |
ParameterList | getFromParameters (const ParameterList &pl) const |
virtual std::vector< std::string > | getAlias (const std::string &name) const |
virtual std::map< std::string, std::string > | getAliases () const |
std::string | getFrom (const std::string &name) const |
bool | hasParameter (const std::string &name) const override |
const ParameterList & | getParameters () const override |
const Parameter & | parameter (const std::string &name) const override |
const std::shared_ptr< Parameter > & | getParameter (const std::string &name) const |
double | getParameterValue (const std::string &name) const override |
void | setAllParametersValues (const ParameterList ¶meters) override |
void | setParameterValue (const std::string &name, double value) override |
void | setParametersValues (const ParameterList ¶meters) override |
bool | matchParametersValues (const ParameterList ¶meters) override |
void | removeConstraint (const std::string &name) override |
void | setConstraint (const std::string &name, std::shared_ptr< ConstraintInterface > constraint) override |
size_t | getNumberOfParameters () const override |
std::string | getNamespace () const override |
std::string | getParameterNameWithoutNamespace (const std::string &name) const override |
virtual const Eigen::VectorXd & | Lik_t (const Eigen::VectorXd &values, double t) const =0 |
const Eigen::VectorXd & | Lik_t (const Eigen::VectorXd &values, double t) const override |
virtual const Eigen::VectorXd & | dLik_dt (const Eigen::VectorXd &values, double t) const =0 |
const Eigen::VectorXd & | dLik_dt (const Eigen::VectorXd &values, double t) const override |
virtual const Eigen::VectorXd & | d2Lik_dt2 (const Eigen::VectorXd &values, double t) const =0 |
const Eigen::VectorXd & | d2Lik_dt2 (const Eigen::VectorXd &values, double t) const override |
virtual const TransitionModelInterface & | transitionModel () const =0 |
const TransitionModelInterface & | transitionModel () const |
bool | isScalable () const |
returns if model is scalable More... | |
void | setScalable (bool scalable) |
sets if model is scalable, ie scale can be changed. Default : true, set to false to avoid normalization for example. More... | |
void | normalize () |
Normalize the generator. More... | |
void | setDiagonal () |
set the diagonal of the generator such that sum on each line equals 0. More... | |
double | getScale () const |
Get the scalar product of diagonal elements of the generator and the frequencies vector. If the generator is normalized, then scale=1. Otherwise each element must be multiplied by 1/scale. More... | |
void | setScale (double scale) |
Multiplies the current generator by the given scale. More... | |
void | addRateParameter () override |
Methods to supersede TransitionModel methods. More... | |
void | setFreqFromData (const SequenceDataInterface &data, double pseudoCount=0) override |
Set equilibrium frequencies equal to the frequencies estimated from the data. More... | |
void | setFreq (std::map< int, double > &frequ) override |
Set equilibrium frequencies. More... | |
virtual void | fireParameterChanged (const ParameterList ¶meters) override |
Methods to supersede AbstractTransitionModel methods. More... | |
void | setNamespace (const std::string &name) override |
double | freq (size_t i) const override |
Methods to supersede TransitionModel methods. More... | |
double | Pij_t (size_t i, size_t j, double t) const override |
double | dPij_dt (size_t i, size_t j, double t) const override |
double | d2Pij_dt2 (size_t i, size_t j, double t) const override |
const Vdouble & | getFrequencies () const override |
const Matrix< double > & | getPij_t (double t) const override |
const Matrix< double > & | getdPij_dt (double t) const override |
const Matrix< double > & | getd2Pij_dt2 (double t) const override |
double | getInitValue (size_t i, int state) const override |
double | getRate () const override |
Get the rate. More... | |
void | setRate (double rate) override |
Set the rate of the model (must be positive). More... | |
bool | computeFrequencies () const override |
void | computeFrequencies (bool yn) override |
const std::vector< int > & | getAlphabetStates () const override |
const StateMapInterface & | stateMap () const override |
std::shared_ptr< const StateMapInterface > | getStateMap () const override |
int | getAlphabetStateAsInt (size_t i) const override |
std::string | getAlphabetStateAsChar (size_t i) const override |
std::vector< size_t > | getModelStates (int code) const override |
Get the state in the model corresponding to a particular state in the alphabet. More... | |
std::vector< size_t > | getModelStates (const std::string &code) const override |
Get the state in the model corresponding to a particular state in the alphabet. More... | |
const Alphabet & | alphabet () const override |
std::shared_ptr< const Alphabet > | getAlphabet () const override |
size_t | getNumberOfStates () const override |
Get the number of states. More... | |
double | Qij (size_t i, size_t j) const |
Methods to supersede SubstitutionModel methods. More... | |
const Matrix< double > & | generator () const |
const Matrix< double > & | exchangeabilityMatrix () const |
double | Sij (size_t i, size_t j) const |
void | enableEigenDecomposition (bool yn) |
Set if eigenValues and Vectors must be computed. More... | |
bool | enableEigenDecomposition () |
Tell if eigenValues and Vectors must be computed. More... | |
bool | isDiagonalizable () const |
bool | isNonSingular () const |
const Vdouble & | getEigenValues () const |
const Vdouble & | getIEigenValues () const |
const Matrix< double > & | getRowLeftEigenVectors () const |
const Matrix< double > & | getColumnRightEigenVectors () const |
Protected Attributes | |
std::map< std::string, std::string > | mapParNamesFromPmodel_ |
Tools to make the link between the Parameters of the object and those of pmixmodel_. More... | |
ParameterList | lParPmodel_ |
Private Attributes | |
std::shared_ptr< const GranthamAAChemicalDistance > | gacd_ |
std::unique_ptr< CodonDistanceFrequenciesSubstitutionModel > | pmodel_ |
ParameterList | independentParameters_ |
std::map< std::string, std::shared_ptr< AliasParameterListener > > | aliasListenersRegister_ |
ParameterList | parameters_ |
std::string | prefix_ |
Eigen::VectorXd | lik_ |
The Goldman and Yang (1994) substitution model for codons.
This model has one rate of transitions and one rate of transversion. It also allows distinct equilibrium frequencies between codons. A multiplicative factor accounts for the selective restraints at the amino acid level. This factor applies on the distance between amino acids given by Grantham (1974).
For codons and , the generator term is:
0 if 2 or 3 of the pair are different.
if exactly 1 of the pairs is different, and that difference is a transversion.
if exactly 1 of the pairs is different, and that difference is a transition.
is a normalization factor.
This model includes 2 parameters ( and ). The codon frequencies are either observed or inferred.
Reference:
GY94::GY94 | ( | std::shared_ptr< const GeneticCode > | gc, |
std::unique_ptr< CodonFrequencySetInterface > | codonFreqs | ||
) |
Definition at line 14 of file GY94.cpp.
References bpp::AbstractParameterAliasable::addParameter_(), bpp::ParameterList::addParameters(), bpp::AbstractParameterAliasable::addParameters_(), bpp::ParameterAliasable::getParameterNameWithoutNamespace(), bpp::AbstractBiblioTransitionModel::lParPmodel_, bpp::AbstractBiblioTransitionModel::mapParNamesFromPmodel_, pmodel_, bpp::Parameter::R_PLUS_STAR, and bpp::AbstractBiblioSubstitutionModel::updateMatrices_().
Referenced by clone().
|
overridevirtualinherited |
Methods to supersede TransitionModel methods.
Implements bpp::BranchModelInterface.
Definition at line 76 of file AbstractBiblioSubstitutionModel.cpp.
References bpp::AbstractParameterAliasable::addParameter_(), bpp::ParameterList::addParameters(), bpp::BranchModelInterface::addRateParameter(), bpp::AbstractParameterAliasable::getNamespace(), bpp::AbstractParameterAliasable::getParameters(), bpp::AbstractTotallyWrappedTransitionModel::getRate(), bpp::AbstractBiblioTransitionModel::lParPmodel_, bpp::AbstractBiblioTransitionModel::mapParNamesFromPmodel_, bpp::AbstractWrappedTransitionModel::model(), bpp::AbstractWrappedTransitionModel::model_(), bpp::Parameter::R_PLUS_STAR, and bpp::ParameterList::reset().
|
inlineoverridevirtualinherited |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 53 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::alphabet(), and bpp::WrappedModelInterface::model().
Referenced by bpp::RegisterRatesSubstitutionModel::alphabet(), and bpp::OneChangeRegisterTransitionModel::OneChangeRegisterTransitionModel().
|
inlineoverridevirtual |
Implements bpp::ReversibleSubstitutionModelInterface.
Definition at line 66 of file GY94.h.
References GY94().
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 162 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::computeFrequencies(), and bpp::WrappedTransitionModelInterface::transitionModel().
Referenced by bpp::DFP07::DFP07(), and bpp::YN98::YN98().
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 171 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::computeFrequencies(), and bpp::AbstractWrappedTransitionModel::transitionModel_().
|
pure virtualinherited |
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 64 of file AbstractSubstitutionModel.h.
References bpp::TransitionModelInterface::getd2Pij_dt2(), and bpp::AbstractLkTransitionModel::lik_.
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 124 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::d2Pij_dt2(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
pure virtualinherited |
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 47 of file AbstractSubstitutionModel.h.
References bpp::TransitionModelInterface::getdPij_dt(), and bpp::AbstractLkTransitionModel::lik_.
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 123 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::dPij_dt(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inlinevirtualinherited |
Tell if eigenValues and Vectors must be computed.
Implements bpp::SubstitutionModelInterface.
Definition at line 240 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::enableEigenDecomposition(), and bpp::AbstractWrappedSubstitutionModel::substitutionModel_().
|
inlinevirtualinherited |
Set if eigenValues and Vectors must be computed.
Implements bpp::SubstitutionModelInterface.
Definition at line 238 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::enableEigenDecomposition(), and bpp::AbstractWrappedSubstitutionModel::substitutionModel_().
|
inlinevirtualinherited |
Implements bpp::SubstitutionModelInterface.
Definition at line 234 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::exchangeabilityMatrix(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlineoverridevirtualinherited |
Methods to supersede AbstractTransitionModel methods.
Tells the model that a parameter value has changed.
This updates the matrices consequently.
Reimplemented from bpp::AbstractParameterAliasable.
Definition at line 86 of file AbstractBiblioSubstitutionModel.h.
References bpp::AbstractParameterAliasable::getNamespace(), bpp::ParameterList::getParameterValue(), bpp::ParameterList::hasParameter(), bpp::AbstractWrappedTransitionModel::model_(), bpp::BranchModelInterface::setRate(), bpp::ParameterList::size(), and bpp::AbstractBiblioTransitionModel::updateMatrices_().
|
inlineoverridevirtualinherited |
Methods to supersede TransitionModel methods.
Implements bpp::TransitionModelInterface.
Definition at line 120 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::freq(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inlineoverridevirtualinherited |
Exception | if no FrequenceSet is associated to this model. |
Reimplemented from bpp::AbstractWrappedModel.
Reimplemented in bpp::RegisterRatesSubstitutionModel, bpp::OneChangeTransitionModel, bpp::OneChangeRegisterTransitionModel, and bpp::YN98.
Definition at line 93 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::frequencySet(), and bpp::WrappedTransitionModelInterface::transitionModel().
Referenced by bpp::RegisterRatesSubstitutionModel::frequencySet().
|
inlinevirtualinherited |
See Kosiol and Goldman (2005), Molecular Biology And Evolution 22(2) 193-9.
Implements bpp::SubstitutionModelInterface.
Definition at line 232 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::generator(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlineoverridevirtualinherited |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 55 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getAlphabet(), and bpp::WrappedModelInterface::model().
Referenced by bpp::RegisterRatesSubstitutionModel::getAlphabet(), and bpp::OneChangeRegisterTransitionModel::OneChangeRegisterTransitionModel().
|
inlineoverridevirtualinherited |
index | The model state. |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 46 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getAlphabetStateAsChar(), and bpp::WrappedModelInterface::model().
Referenced by bpp::RegisterRatesSubstitutionModel::getAlphabetStateAsChar().
|
inlineoverridevirtualinherited |
index | The model state. |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 44 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getAlphabetStateAsInt(), and bpp::WrappedModelInterface::model().
Referenced by bpp::RegisterRatesSubstitutionModel::getAlphabetStateAsInt().
|
inlineoverridevirtualinherited |
@ brief Methods to supersede TransitionModel methods.
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 38 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getAlphabetStates(), and bpp::WrappedModelInterface::model().
Referenced by bpp::RegisterRatesSubstitutionModel::getAlphabetStates().
|
inline |
|
inlinevirtualinherited |
Implements bpp::SubstitutionModelInterface.
Definition at line 252 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::getColumnRightEigenVectors(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 132 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::getd2Pij_dt2(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 130 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::getdPij_dt(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inlinevirtualinherited |
Implements bpp::SubstitutionModelInterface.
Definition at line 246 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::getEigenValues(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 126 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::getFrequencies(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inlineoverrideprotectedvirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 181 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::getFrequencies_(), and bpp::AbstractWrappedTransitionModel::transitionModel_().
|
inline |
|
inlinevirtualinherited |
Implements bpp::SubstitutionModelInterface.
Definition at line 248 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::getIEigenValues(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlineoverridevirtualinherited |
This method is used to initialize likelihoods in recursions. It typically sends 1 if i = state, 0 otherwise, where i is one of the possible states of the alphabet allowed in the model and state is the observed state in the considered sequence/site.
i | the index of the state in the model. |
state | An observed state in the sequence/site. |
IndexOutOfBoundsException | if array position is out of range. |
BadIntException | if states are not allowed in the associated alphabet. |
Implements bpp::BranchModelInterface.
Definition at line 134 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getInitValue(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inlineoverridevirtualinherited |
Get the state in the model corresponding to a particular state in the alphabet.
code | The alphabet state to check. |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 50 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getModelStates(), and bpp::WrappedModelInterface::model().
|
inlineoverridevirtualinherited |
Get the state in the model corresponding to a particular state in the alphabet.
code | The alphabet state to check. |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 48 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getModelStates(), and bpp::WrappedModelInterface::model().
Referenced by bpp::RegisterRatesSubstitutionModel::getModelStates().
|
inlineoverridevirtual |
|
inlineoverridevirtualinherited |
Get the number of states.
For most models, this equals the size of the alphabet.
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 57 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getNumberOfStates(), and bpp::WrappedModelInterface::model().
|
inherited |
get the name of a parameter from its name in a submodel
name | the name of the parameter in the submodel |
Definition at line 37 of file AbstractBiblioSubstitutionModel.cpp.
References bpp::AbstractBiblioTransitionModel::mapParNamesFromPmodel_.
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 128 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::getPij_t(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inherited |
get the name of a parameter in the submodel from its apparent name
name | the name of the parameter |
Definition at line 47 of file AbstractBiblioSubstitutionModel.cpp.
References bpp::AbstractBiblioTransitionModel::mapParNamesFromPmodel_.
|
inlineoverridevirtualinherited |
Get the rate.
Implements bpp::BranchModelInterface.
Definition at line 139 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getRate(), and bpp::WrappedTransitionModelInterface::transitionModel().
Referenced by bpp::AbstractBiblioTransitionModel::addRateParameter(), and bpp::FromMixtureSubstitutionModel::addRateParameter().
|
inlinevirtualinherited |
Implements bpp::SubstitutionModelInterface.
Definition at line 250 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::getRowLeftEigenVectors(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlinevirtualinherited |
Get the scalar product of diagonal elements of the generator and the frequencies vector. If the generator is normalized, then scale=1. Otherwise each element must be multiplied by 1/scale.
Implements bpp::SubstitutionModelInterface.
Definition at line 278 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::getScale(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlineoverridevirtualinherited |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 42 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::getStateMap(), and bpp::WrappedModelInterface::model().
Referenced by bpp::RegisterRatesSubstitutionModel::getStateMap().
|
inlinevirtualinherited |
Implements bpp::SubstitutionModelInterface.
Definition at line 242 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::isDiagonalizable(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlinevirtualinherited |
Implements bpp::SubstitutionModelInterface.
Definition at line 244 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::isNonSingular(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlinevirtualinherited |
returns if model is scalable
Implements bpp::SubstitutionModelInterface.
Definition at line 258 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::isScalable(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
pure virtualinherited |
This method is used to compute likelihoods in recursions. It computes the probability of a vector given a start state.
values | An vector of states on the site. |
t | time |
IndexOutOfBoundsException | if array position is out of range. |
BadIntException | if states are not allowed in the associated alphabet. |
Implemented in bpp::AbstractLkTransitionModel, bpp::TransitionModelInterface, bpp::TransitionFromTransitionModel, and bpp::MultinomialFromTransitionModel.
|
inlineoverridevirtualinherited |
This method is used to compute likelihoods in recursions. It computes the probability of a vector given a start state.
values | An vector of states on the site. |
t | the branch length |
Implements bpp::TransitionModelInterface.
Definition at line 30 of file AbstractSubstitutionModel.h.
References bpp::TransitionModelInterface::getPij_t(), and bpp::AbstractLkTransitionModel::lik_.
|
inlineoverridevirtualinherited |
Implements bpp::WrappedModelInterface.
Definition at line 98 of file AbstractWrappedModel.h.
References bpp::WrappedTransitionModelInterface::transitionModel().
Referenced by bpp::AbstractBiblioTransitionModel::addRateParameter(), bpp::FromMixtureSubstitutionModel::addRateParameter(), bpp::InMixedSubstitutionModel::getInitValue(), bpp::FromMixtureSubstitutionModel::getName(), bpp::RegisterRatesSubstitutionModel::getRate(), bpp::AbstractBiblioSubstitutionModel::operator=(), bpp::AbstractBiblioTransitionModel::operator=(), bpp::RegisterRatesSubstitutionModel::RegisterRatesSubstitutionModel(), bpp::AbstractBiblioTransitionModel::setFreq(), bpp::AbstractBiblioTransitionModel::setNamespace(), and bpp::BppOSubstitutionModelFormat::write().
|
inlineprotectedinherited |
Definition at line 85 of file AbstractWrappedModel.h.
References bpp::AbstractWrappedTransitionModel::transitionModel_().
Referenced by bpp::AbstractBiblioTransitionModel::addRateParameter(), bpp::FromMixtureSubstitutionModel::addRateParameter(), bpp::AbstractBiblioTransitionModel::fireParameterChanged(), bpp::FromMixtureSubstitutionModel::fireParameterChanged(), bpp::RegisterRatesSubstitutionModel::RegisterRatesSubstitutionModel(), bpp::AbstractBiblioTransitionModel::setNamespace(), bpp::FromMixtureSubstitutionModel::setNamespace(), bpp::RegisterRatesSubstitutionModel::setRate(), and bpp::AbstractBiblioTransitionModel::updateMatrices_().
|
inlinevirtualinherited |
Normalize the generator.
Implements bpp::SubstitutionModelInterface.
Definition at line 268 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::normalize(), and bpp::AbstractWrappedSubstitutionModel::substitutionModel_().
Definition at line 65 of file GY94.cpp.
References bpp::AbstractBiblioSubstitutionModel::operator=(), and pmodel_.
|
inlineoverridevirtualinherited |
Implements bpp::TransitionModelInterface.
Definition at line 122 of file AbstractWrappedModel.h.
References bpp::TransitionModelInterface::Pij_t(), and bpp::WrappedTransitionModelInterface::transitionModel().
|
inlinevirtualinherited |
Methods to supersede SubstitutionModel methods.
Implements bpp::SubstitutionModelInterface.
Definition at line 230 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::Qij(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlinevirtualinherited |
set the diagonal of the generator such that sum on each line equals 0.
Implements bpp::SubstitutionModelInterface.
Definition at line 273 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::setDiagonal(), and bpp::AbstractWrappedSubstitutionModel::substitutionModel_().
|
overridevirtualinherited |
Set equilibrium frequencies.
frequencies | The map of the frequencies to use. |
Implements bpp::TransitionModelInterface.
Reimplemented in bpp::YN98, bpp::MG94, and bpp::KCM.
Definition at line 111 of file AbstractBiblioSubstitutionModel.cpp.
References bpp::ParameterList::addParameter(), bpp::AbstractParameterAliasable::getNamespace(), bpp::AbstractParameterAliasable::getParameterNameWithoutNamespace(), bpp::AbstractParameterAliasable::getParameterValue(), bpp::AbstractBiblioTransitionModel::mapParNamesFromPmodel_, bpp::AbstractParameterAliasable::matchParametersValues(), bpp::AbstractWrappedTransitionModel::model(), and bpp::AbstractTotallyWrappedTransitionModel::setFreq().
Referenced by bpp::KCM::setFreq(), bpp::MG94::setFreq(), bpp::YN98::setFreq(), and bpp::AbstractBiblioTransitionModel::setFreqFromData().
|
overridevirtualinherited |
Set equilibrium frequencies equal to the frequencies estimated from the data.
data | The sequences to use. |
pseudoCount | A quantity to add to adjust the observed values in order to prevent issues due to missing states on small data set. The corrected frequencies shall be computed as
|
Implements bpp::TransitionModelInterface.
Definition at line 125 of file AbstractBiblioSubstitutionModel.cpp.
References bpp::SequenceContainerTools::getFrequencies(), and bpp::AbstractBiblioTransitionModel::setFreq().
|
overridevirtualinherited |
Reimplemented from bpp::AbstractParameterAliasable.
Definition at line 88 of file AbstractBiblioSubstitutionModel.cpp.
References bpp::ParameterList::addParameters(), bpp::ParameterAliasable::getParameterNameWithoutNamespace(), bpp::AbstractParameterAliasable::getParameters(), bpp::AbstractBiblioTransitionModel::lParPmodel_, bpp::AbstractBiblioTransitionModel::mapParNamesFromPmodel_, bpp::AbstractWrappedTransitionModel::model(), bpp::AbstractWrappedTransitionModel::model_(), bpp::ParameterList::reset(), bpp::AbstractParameterAliasable::setNamespace(), and bpp::ParameterAliasable::setNamespace().
|
inlineoverridevirtualinherited |
Set the rate of the model (must be positive).
rate | must be positive. |
Implements bpp::BranchModelInterface.
Definition at line 144 of file AbstractWrappedModel.h.
References bpp::BranchModelInterface::setRate(), and bpp::AbstractWrappedTransitionModel::transitionModel_().
|
inlinevirtualinherited |
sets if model is scalable, ie scale can be changed. Default : true, set to false to avoid normalization for example.
Implements bpp::SubstitutionModelInterface.
Definition at line 263 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::setScalable(), and bpp::AbstractWrappedSubstitutionModel::substitutionModel_().
|
inlinevirtualinherited |
Multiplies the current generator by the given scale.
scale | the scale by which the generator is multiplied. |
Implements bpp::SubstitutionModelInterface.
Definition at line 283 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::setScale(), and bpp::AbstractWrappedSubstitutionModel::substitutionModel_().
|
inlinevirtualinherited |
By definition Sij(i,j) = Sij(j,i).
Implements bpp::SubstitutionModelInterface.
Definition at line 236 of file AbstractWrappedModel.h.
References bpp::SubstitutionModelInterface::Sij(), and bpp::WrappedSubstitutionModelInterface::substitutionModel().
|
inlineoverridevirtualinherited |
Implements bpp::BranchModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 40 of file AbstractWrappedModel.h.
References bpp::WrappedModelInterface::model(), and bpp::BranchModelInterface::stateMap().
Referenced by bpp::RegisterRatesSubstitutionModel::stateMap().
|
inlineoverridevirtual |
Implements bpp::WrappedSubstitutionModelInterface.
Definition at line 71 of file GY94.h.
References pmodel_.
|
inlineoverrideprotectedvirtual |
Implements bpp::AbstractWrappedSubstitutionModel.
Definition at line 78 of file GY94.h.
References pmodel_.
|
inlinevirtualinherited |
Implements bpp::WrappedTransitionModelInterface.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 199 of file AbstractWrappedModel.h.
References bpp::WrappedSubstitutionModelInterface::substitutionModel().
Referenced by bpp::InMixedSubstitutionModel::d2Pij_dt2(), bpp::InMixedSubstitutionModel::dPij_dt(), bpp::InMixedSubstitutionModel::freq(), bpp::InMixedSubstitutionModel::getd2Pij_dt2(), bpp::InMixedSubstitutionModel::getdPij_dt(), bpp::InMixedSubstitutionModel::getFrequencies(), bpp::InMixedSubstitutionModel::getPij_t(), bpp::InMixedSubstitutionModel::getRate(), and bpp::InMixedSubstitutionModel::Pij_t().
|
pure virtualinherited |
Implemented in bpp::RegisterRatesSubstitutionModel, bpp::AbstractFromSubstitutionModelTransitionModel, bpp::AbstractBiblioMixedTransitionModel, and bpp::AbstractWrappedSubstitutionModel.
Referenced by bpp::AbstractTotallyWrappedTransitionModel::computeFrequencies(), bpp::AbstractTotallyWrappedTransitionModel::d2Pij_dt2(), bpp::AbstractTotallyWrappedTransitionModel::dPij_dt(), bpp::AbstractTotallyWrappedTransitionModel::freq(), bpp::AbstractWrappedTransitionModel::frequencySet(), bpp::AbstractTotallyWrappedTransitionModel::getd2Pij_dt2(), bpp::AbstractTotallyWrappedTransitionModel::getdPij_dt(), bpp::AbstractTotallyWrappedTransitionModel::getFrequencies(), bpp::AbstractTotallyWrappedTransitionModel::getInitValue(), bpp::AbstractTotallyWrappedTransitionModel::getPij_t(), bpp::AbstractTotallyWrappedTransitionModel::getRate(), bpp::AbstractWrappedTransitionModel::model(), and bpp::AbstractTotallyWrappedTransitionModel::Pij_t().
|
inlineprotectedvirtualinherited |
Implements bpp::AbstractWrappedTransitionModel.
Reimplemented in bpp::RegisterRatesSubstitutionModel.
Definition at line 205 of file AbstractWrappedModel.h.
References bpp::AbstractWrappedSubstitutionModel::substitutionModel_().
|
protectedpure virtualinherited |
Implemented in bpp::RegisterRatesSubstitutionModel, bpp::AbstractFromSubstitutionModelTransitionModel, bpp::AbstractBiblioMixedTransitionModel, and bpp::AbstractWrappedSubstitutionModel.
Referenced by bpp::AbstractTotallyWrappedTransitionModel::computeFrequencies(), bpp::AbstractTotallyWrappedTransitionModel::getFrequencies_(), bpp::AbstractWrappedTransitionModel::model_(), bpp::AbstractTotallyWrappedTransitionModel::setFreq(), bpp::AbstractTotallyWrappedTransitionModel::setFreqFromData(), and bpp::AbstractTotallyWrappedTransitionModel::setRate().
|
inlineoverrideprotectedvirtualinherited |
Reimplemented from bpp::AbstractBiblioTransitionModel.
Definition at line 129 of file AbstractBiblioSubstitutionModel.h.
References bpp::AbstractBiblioTransitionModel::updateMatrices_().
Referenced by GY94(), bpp::KCM::KCM(), bpp::MG94::MG94(), and bpp::YN98::YN98().
|
private |
|
mutableprivateinherited |
Definition at line 23 of file AbstractSubstitutionModel.h.
Referenced by bpp::AbstractLkTransitionModel::d2Lik_dt2(), bpp::AbstractLkTransitionModel::dLik_dt(), and bpp::AbstractLkTransitionModel::Lik_t().
|
protectedinherited |
Definition at line 30 of file AbstractBiblioSubstitutionModel.h.
Referenced by bpp::AbstractBiblioTransitionModel::addRateParameter(), bpp::DFP07::DFP07(), GY94(), bpp::KCM::KCM(), bpp::LG10_EX_EHO::LG10_EX_EHO(), bpp::LGL08_CAT::LGL08_CAT(), bpp::LLG08_EHO::LLG08_EHO(), bpp::LLG08_EX2::LLG08_EX2(), bpp::LLG08_EX3::LLG08_EX3(), bpp::LLG08_UL2::LLG08_UL2(), bpp::LLG08_UL3::LLG08_UL3(), bpp::MG94::MG94(), bpp::AbstractBiblioTransitionModel::operator=(), bpp::RELAX::RELAX(), bpp::AbstractBiblioTransitionModel::setNamespace(), bpp::AbstractBiblioTransitionModel::updateMatrices_(), bpp::RELAX::updateMatrices_(), bpp::YNGP_M3::updateMatrices_(), bpp::YN98::YN98(), bpp::YNGP_M1::YNGP_M1(), bpp::YNGP_M10::YNGP_M10(), bpp::YNGP_M2::YNGP_M2(), bpp::YNGP_M3::YNGP_M3(), bpp::YNGP_M7::YNGP_M7(), bpp::YNGP_M8::YNGP_M8(), and bpp::YNGP_M9::YNGP_M9().
|
protectedinherited |
Tools to make the link between the Parameters of the object and those of pmixmodel_.
Definition at line 28 of file AbstractBiblioSubstitutionModel.h.
Referenced by bpp::AbstractBiblioTransitionModel::addRateParameter(), bpp::DFP07::DFP07(), bpp::AbstractBiblioTransitionModel::getParNameFromPmodel(), bpp::AbstractBiblioTransitionModel::getPmodelParName(), GY94(), bpp::KCM::KCM(), bpp::LG10_EX_EHO::LG10_EX_EHO(), bpp::LGL08_CAT::LGL08_CAT(), bpp::LLG08_EHO::LLG08_EHO(), bpp::LLG08_EX2::LLG08_EX2(), bpp::LLG08_EX3::LLG08_EX3(), bpp::LLG08_UL2::LLG08_UL2(), bpp::LLG08_UL3::LLG08_UL3(), bpp::MG94::MG94(), bpp::AbstractBiblioTransitionModel::operator=(), bpp::RELAX::RELAX(), bpp::AbstractBiblioTransitionModel::setFreq(), bpp::AbstractBiblioTransitionModel::setNamespace(), bpp::AbstractBiblioTransitionModel::updateMatrices_(), bpp::RELAX::updateMatrices_(), bpp::YNGP_M3::updateMatrices_(), bpp::YN98::YN98(), bpp::YNGP_M1::YNGP_M1(), bpp::YNGP_M10::YNGP_M10(), bpp::YNGP_M2::YNGP_M2(), bpp::YNGP_M3::YNGP_M3(), bpp::YNGP_M7::YNGP_M7(), bpp::YNGP_M8::YNGP_M8(), and bpp::YNGP_M9::YNGP_M9().
|
private |
Definition at line 53 of file GY94.h.
Referenced by getCodonsMulRate(), getGeneticCode(), GY94(), operator=(), substitutionModel(), and substitutionModel_().